About This Web Site
TCNG (The Cancer Network Galaxy) is a database of cancer gene networks estimated from the publicly available cancer gene expression data. The gene networks are estimated using the Japanese national flagship supercomputer "K computer." This is a result of ISLiM project which aims at developing biological software that utilizes "K computer." This is supported by many projects; See Acknowledgements below for the full list.
TCNG is currently under development and available as a beta release.
Members
TCNG is developed by
Yoshinori Tamada
Atsushi Niida
Ayumu Saito
Georg Tremmel
Teppei Shimamura
Rui Yamaguchi
Seiya Imoto
and
Satoru Miyano
Acknowledgements
TCNG is supported by ISLiM (Next-generation integrated simulation of living matter) project in RIKEN Computational Science Research Program, HPCI Strategic Program Computational Life Science and Application in Drug Discovery and Medical Development, and the Systems Cancer project of the Grants-in-Aid for Scientific Research on Innovative Areas, MEXT, Japan. SiGN-BN includes the results of the project "An evolutionary approach to construction of a software development environment for massively-parallel heterogeneous systems" supported by JST, CREST. The computational resource is provided by RIKEN AICS K Computer.
Release Note
Release 0.14 built on Wed Mar 30 15:00:31 2016
256 EGF related networks are added.
The Number of Array Sets: 256 GEO array sets
The Number of Gene Sets: 768 sets
The Number of Networks: 768
The Number of Genes: 22,820
The Number of Nodes: 24,907
The Number of Edges: 16,545,373
Methods: SiGN-BN NNSR, SiGN-BN HC+Bootstrap
Resource: RIKEN AICS K computer
Release 0.13 built on Tue Feb 26 10:55:17 2013
The second update beta release of TCNG.
The Number of Array Sets: 256 GEO array sets
The Number of Gene Sets: 512 sets
The Number of Networks: 512
The Number of Genes: 22,820
The Number of Nodes: 24,896
The Number of Edges: 11,610,582
Methods: SiGN-BN NNSR, SiGN-BN HC+Bootstrap
Resource: RIKEN AICS K computer
Release 0.12 built on Thu Dec 6 17:23:31 2012
The first (beta) release of TCNG.
Number of networks: 256.
Number of unique genes: 22,819.
Number of edges: 9,940,792.
Datasets: 256 GEO Datasets.
Methods: SiGN-BN NNSR.
Resource: RIKEN AICS K computer.
