Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	CNOT8	39	3	42	979.826
#2	BACH2	38	6	44	1107.186
#3	PRRX1	37	2	39	270.544
#4	RUNX1T1	36	2	38	93.291
#5	ZEB1	35	2	37	2090.826
#6	GTF2I	35	5	40	1734.93
#7	ZFPM2	35	2	37	44.31
#8	CREB1	33	5	38	239.734
#9	SPEN	31	2	33	48.779
#10	SP1	31	0	31	0
#11	TFAM	31	2	33	545.444
#12	NFATC3	31	4	35	531.985
#13	SLC2A4RG	30	5	35	581.487
#14	AEBP1	30	5	35	161.696
#15	PTTG1	30	6	36	898.433
#16	ZKSCAN5	30	5	35	1345.127
#17	SIX5	29	7	36	1114.929
#18	MYBL2	29	8	37	2084.463
#19	HIC1	29	9	38	606.793
#20	TBX5	29	5	34	5680.017
#21	FOXM1	29	2	31	2215.363
#22	ZNF394	29	1	30	20.137
#23	TSHZ3	28	4	32	553.256
#24	ZNF33A	27	8	35	1123.934
#25	EBF1	27	5	32	160.847
#26	BHLHE41	26	12	38	2032.973
#27	TCF4	26	6	32	298.508
#28	MMP14	26	7	33	412.078
#29	ZBTB38	26	5	31	498.073
#30	UBN1	26	7	33	975.065
#31	C5orf41	26	11	37	4500.176
#32	ZNF148	26	10	36	693.927
#33	ZNF277	26	3	29	769.523
#34	NFYB	25	8	33	454.46
#35	MLLT10	25	11	36	709.41
#36	TFEB	25	7	32	1360.744
#37	KLF12	25	15	40	815.003
#38	SMAD9	25	10	35	562.239
#39	ZNF140	25	15	40	2757.318
#40	ZNF444	25	7	32	1562.459
#41	GATAD1	25	10	35	1793.522
#42	GLIS2	25	8	33	437.927
#43	UHRF1	25	3	28	194.041
#44	SNAI2	25	10	35	1179.222
#45	IKZF1	24	2	26	580.096
#46	ZNF268	24	12	36	958.633
#47	MEF2C	24	8	32	972.419
#48	ERG	24	3	27	258.819
#49	TCF7L2	24	13	37	1163.145
#50	LCOR	24	8	32	1018.985
#51	E2F8	24	6	30	382.1
#52	STAT1	24	6	30	478.152
#53	HMGB1	23	10	33	589.521
#54	ETS1	23	6	29	2148.714
#55	AATF	23	12	35	1602.415
#56	TAF4	23	6	29	972.507
#57	SMAD4	23	7	30	1174.828
#58	LHX2	23	4	27	682.289
#59	CREB3L4	23	7	30	1365.375
#60	BHLHE40	23	16	39	2188.736
#61	FOXP2	23	5	28	202.44
#62	SOX4	23	11	34	2354.372
#63	TWIST1	22	12	34	2513.301
#64	ESR1	22	14	36	2115.492
#65	HCLS1	22	1	23	14.92
#66	BACH1	22	6	28	520.668
#67	RUNX2	22	8	30	139.255
#68	FOXO1	22	15	37	563.119
#69	FOXP4	22	5	27	455.099
#70	ENO1	22	9	31	1139.85
#71	ZNF18	22	9	31	1702.311
#72	SMAD5	21	0	21	0
#73	ARID4A	21	7	28	1566.441
#74	KLF6	21	12	33	1325.245
#75	ARNT2	21	14	35	3103.984
#76	YEATS4	21	11	32	1470.334
#77	HOXA5	21	3	24	349.689
#78	ZNF134	21	10	31	2183.774
#79	SPIB	21	2	23	249.165
#80	SMAD1	21	15	36	2113.574
#81	NR3C1	21	13	34	1126.704
#82	SOX7	20	9	29	463.775
#83	YY1	20	9	29	1732.237
#84	TSHZ2	20	10	30	289.944
#85	E2F1	20	7	27	628.205
#86	ZIC2	20	17	37	1390.42
#87	POU2F2	20	6	26	253.51
#88	ZEB2	20	8	28	340.04
#89	MLX	20	15	35	2399.273
#90	ETV1	19	9	28	251.932
#91	MEIS2	19	11	30	902.125
#92	ZNF45	19	7	26	767.319
#93	NFX1	19	10	29	769.491
#94	ATF6	19	16	35	1252.44
#95	ATF1	19	5	24	2767.992
#96	HSF1	19	15	34	1698.058
#97	ZNF236	19	12	31	1564.925
#98	HLF	19	13	32	1719.859
#99	BCL11B	19	8	27	1626.858
#100	CREB3	19	9	28	2692.546
#101	GLIS3	19	11	30	657.795
#102	HHEX	19	20	39	3138.928
#103	TCF19	19	3	22	52.602
#104	HOXA7	19	8	27	1473.868
#105	MEF2A	18	8	26	473.966
#106	MAFK	18	12	30	2156.663
#107	SOX10	18	7	25	342.288
#108	THRB	18	16	34	1870.945
#109	MEIS1	18	10	28	764.335
#110	ZKSCAN1	18	9	27	1376.761
#111	ZNF217	18	18	36	2222.261
#112	MLL	18	3	21	33.447
#113	PRDM1	18	14	32	3782.02
#114	EPAS1	18	18	36	1142.973
#115	NFKB1	18	13	31	2047.13
#116	SP140	18	5	23	128.07
#117	GSC	18	10	28	1857.328
#118	TAF4B	18	17	35	1687.989
#119	CREB3L2	18	12	30	1105.924
#120	E2F3	18	11	29	1612.602
#121	GAS7	18	12	30	757.325
#122	MEIS3P1	18	12	30	1549.733
#123	L3MBTL4	18	16	34	1356.589
#124	NFIX	18	23	41	2028.009
#125	ZFP36L2	18	20	38	1472.595
#126	NFIA	18	13	31	691.167
#127	BLZF1	17	9	26	1117.162
#128	LASS2	17	13	30	1563.13
#129	RBCK1	17	19	36	2340.262
#130	NFYC	17	5	22	579.699
#131	HOXB9	17	3	20	429.506
#132	YBX1	17	9	26	487.611
#133	GLI3	17	19	36	1425.7
#134	E2F7	17	10	27	513.266
#135	EGR1	17	4	21	879.239
#136	HOXA9	17	10	27	1146.466
#137	IRF8	17	3	20	801.482
#138	ATF7	17	12	29	1067.544
#139	HOXA2	17	7	24	506.84
#140	CREB3L1	17	16	33	2018.779
#141	FLI1	17	10	27	946.744
#142	BTG2	17	8	25	961.374
#143	FOXO3	17	11	28	1036.436
#144	ELF1	17	9	26	616.615
#145	RORA	17	9	26	1347.156
#146	RERE	17	9	26	1036.068
#147	RCOR1	16	17	33	1776.151
#148	MAFB	16	12	28	446.813
#149	SUPT6H	16	18	34	1941.716
#150	CREBL2	16	8	24	848.77
#151	NFAT5	16	7	23	358.195
#152	SPDEF	16	19	35	1085.997
#153	SMAD6	16	16	32	1344.083
#154	ZFHX4	16	9	25	275.697
#155	HOXA3	16	9	25	1049.819
#156	BTAF1	16	9	25	2864.358
#157	KLF4	16	15	31	4627.764
#158	TCF25	16	9	25	646.059
#159	ZNF33B	16	12	28	1097.406
#160	TRPS1	16	14	30	4245.962
#161	FOXA3	16	13	29	2151.353
#162	ZNF238	16	22	38	2349.329
#163	E2F5	16	16	32	1465.819
#164	TP63	15	8	23	842.068
#165	PEG3	15	17	32	3228.627
#166	WNT5A	15	21	36	1716.015
#167	FOS	15	6	21	1338.421
#168	NFIB	15	21	36	903.318
#169	HOXB7	15	11	26	1395.394
#170	ATF3	15	9	24	680.335
#171	PAX7	15	12	27	886.807
#172	TEAD2	15	12	27	906.534
#173	EGR2	15	5	20	306.931
#174	ZNF500	15	11	26	1036.493
#175	TEF	15	12	27	1444.229
#176	GRHL2	15	12	27	1439.88
#177	TCF12	15	10	25	1009.858
#178	STAT3	15	16	31	1458.063
#179	MGA	15	9	24	496.06
#180	STAT4	15	9	24	1806.836
#181	KLF10	15	16	31	1436.004
#182	DRAP1	15	17	32	1267.737
#183	TEAD1	15	13	28	788.868
#184	CREBBP	15	9	24	397.203
#185	ZNF193	15	9	24	1153.49
#186	HR	15	18	33	2259.568
#187	CSRNP3	14	14	28	1317.76
#188	NFE2L1	14	7	21	939.372
#189	TFCP2	14	10	24	1329.051
#190	GATA3	14	21	35	2130.069
#191	JUNB	14	3	17	173.105
#192	FOXD1	14	11	25	2801.253
#193	HOXA1	14	6	20	884.022
#194	HOXC10	14	10	24	1020.769
#195	PLSCR1	14	11	25	512.59
#196	STRN3	14	7	21	4417.969
#197	TAF12	14	12	26	1314.781
#198	ETS2	14	9	23	1639.705
#199	BCL3	14	14	28	1052.806
#200	ARX	14	13	27	1655.569
#201	IRF1	14	10	24	1236.366
#202	ZNF24	14	12	26	994.138
#203	TWIST2	14	13	27	255.747
#204	FOSB	14	3	17	107.2
#205	ZHX2	14	12	26	1708.885
#206	CBFA2T2	14	11	25	1757.663
#207	HOXC11	13	7	20	754.806
#208	IRX1	13	10	23	406.535
#209	KDM5A	13	10	23	956.927
#210	PBX1	13	12	25	1033.643
#211	HMGA1	13	19	32	1667.246
#212	HOXC9	13	12	25	876.08
#213	ZNF207	13	20	33	2748.501
#214	HSF2	13	14	27	1029.979
#215	HOXC4	13	10	23	1116.382
#216	SOX8	13	13	26	2253.888
#217	RCAN1	13	14	27	2428.556
#218	NFIC	13	13	26	1562.826
#219	PPARG	13	20	33	1249.24
#220	LASS6	13	17	30	994.134
#221	PURB	13	12	25	1788.907
#222	FOXG1	13	6	19	732.173
#223	IRF9	13	6	19	1920.885
#224	SCAND1	13	13	26	1359.264
#225	CEBPB	13	18	31	2179.454
#226	RFXAP	13	12	25	830.155
#227	SALL1	13	12	25	1701.6
#228	TEAD3	13	13	26	599.555
#229	NANOG	13	15	28	1720.129
#230	ZNF397	13	13	26	1162.733
#231	PITX2	13	6	19	9353.192
#232	FOSL2	13	13	26	1865.989
#233	ZSCAN18	12	16	28	1531.138
#234	TBX3	12	19	31	1424.583
#235	RARA	12	15	27	1079.996
#236	HMGA2	12	9	21	474.693
#237	NR4A1	12	5	17	603.071
#238	ONECUT2	12	11	23	1277.76
#239	ZHX1	12	20	32	1733.55
#240	HOXD1	12	9	21	523.188
#241	RUNX3	12	9	21	525.606
#242	ZNF639	12	15	27	1953.164
#243	HMGB2	12	9	21	236.964
#244	ZHX3	12	12	24	2499.77
#245	SALL2	12	19	31	1523.396
#246	MYCL1	12	13	25	1290.084
#247	ZNF117	12	15	27	2094.787
#248	SATB1	12	18	30	869.626
#249	CNOT7	12	13	25	835.62
#250	BUD31	12	7	19	647.393
#251	HIF1A	12	14	26	529.88
#252	MEOX1	12	15	27	1794.95
#253	GCM1	12	8	20	666.336
#254	KLF5	12	20	32	1612.958
#255	FOXA1	12	22	34	1898.989
#256	TGIF2	12	13	25	664.854
#257	HOXD4	12	10	22	700.363
#258	HOXD3	12	13	25	829.708
#259	AHCTF1	12	12	24	616.933
#260	SOX17	12	13	25	1575.207
#261	MEOX2	12	7	19	1205.049
#262	KLF9	12	16	28	1264.145
#263	ETV7	12	8	20	1206.544
#264	KDM5B	12	15	27	1166.45
#265	TBX2	12	14	26	1346.236
#266	MSRB2	12	13	25	1159.661
#267	FOXN3	12	15	27	2043.22
#268	ETV6	12	12	24	462.897
#269	TCF3	12	16	28	1052.892
#270	EGR3	11	18	29	1984.907
#271	AFF4	11	11	22	409.128
#272	TSHZ1	11	16	27	1495.417
#273	SOX13	11	16	27	873.409
#274	TAF5L	11	15	26	709.648
#275	HOXC13	11	16	27	877.002
#276	SLC26A3	11	25	36	1890.912
#277	VTN	11	9	20	637.327
#278	MNX1	11	15	26	970.71
#279	HMG20B	11	16	27	742.753
#280	ZNF138	11	10	21	837.212
#281	CEBPD	11	11	22	778.351
#282	NR4A2	11	24	35	2397.459
#283	CSRNP1	11	10	21	1326.8
#284	CTNNB1	11	13	24	607.752
#285	PHTF1	11	16	27	1361.631
#286	NR2C1	11	23	34	864.29
#287	NFATC2	11	10	21	421.408
#288	EOMES	11	7	18	715.587
#289	CSRNP2	11	17	28	6856.175
#290	CREBZF	11	18	29	2118.123
#291	TRIM29	11	17	28	2763.197
#292	JUN	11	8	19	992.437
#293	IRX3	11	13	24	1108.506
#294	JDP2	11	19	30	1194.992
#295	FOXO6	10	16	26	1598.57
#296	ELF4	10	15	25	885.058
#297	NFYA	10	17	27	1084.93
#298	HDX	10	12	22	681.027
#299	ZNF85	10	13	23	824.045
#300	FOXN2	10	13	23	1021.038
#301	NR4A3	10	5	15	339.823
#302	CSDA	10	14	24	750.365
#303	IRX5	10	10	20	814.861
#304	MYNN	10	19	29	1302.756
#305	ZNF367	10	9	19	615.193
#306	MESP2	10	10	20	1102.09
#307	HOXB6	10	7	17	713.149
#308	IRX2	10	27	37	1254.126
#309	FOXP1	10	9	19	692.618
#310	ZNF232	10	12	22	605.141
#311	RORB	10	10	20	644.756
#312	HOXB2	10	15	25	1316.038
#313	NKX3-1	10	19	29	786.784
#314	ZFHX3	10	18	28	975.816
#315	NR1H3	10	17	27	1549.551
#316	HEY2	10	17	27	1804.058
#317	DLX3	10	13	23	611.385
#318	NOLC1	10	18	28	1021.914
#319	JUND	10	14	24	1150.885
#320	MYC	10	22	32	1851.092
#321	TCEAL1	10	18	28	1168.25
#322	NR2F6	10	7	17	1216.513
#323	TFEC	10	9	19	944.728
#324	DLX1	10	12	22	1169.236
#325	SOLH	9	12	21	1868.535
#326	GATA2	9	18	27	1328.55
#327	MAF	9	22	31	1114.268
#328	IRF6	9	21	30	737.882
#329	RUNX1	9	17	26	815.467
#330	REL	9	17	26	912.82
#331	MYT1	9	17	26	423.921
#332	SCAND3	9	18	27	1167.542
#333	ZNF323	9	19	28	1843.024
#334	ZNF135	9	11	20	2451.565
#335	BATF2	9	11	20	453.688
#336	SATB2	9	18	27	1349.516
#337	PCGF2	9	19	28	1323.116
#338	HOXD8	9	12	21	501.005
#339	DBP	9	17	26	2347.515
#340	NFIL3	9	22	31	1248.768
#341	TFCP2L1	9	16	25	905.662
#342	ETV4	9	22	31	1284.84
#343	KLF7	9	14	23	357.543
#344	ZFP36L1	9	20	29	1084.056
#345	NR2F2	9	22	31	1656.466
#346	THRA	9	11	20	539.911
#347	GATAD2B	9	18	27	1813.032
#348	HOPX	9	15	24	1152.664
#349	SMAD3	9	16	25	1698.639
#350	ARNTL	9	12	21	367.539
#351	HOXA10	9	17	26	776.347
#352	NPAS2	9	23	32	1308.574
#353	VAX2	9	13	22	769.21
#354	RXRB	9	13	22	976.619
#355	SP4	9	21	30	1460.337
#356	SOX11	9	22	31	1133.905
#357	NFXL1	9	16	25	1383.956
#358	FUBP1	9	19	28	2208.95
#359	HEYL	9	12	21	882.745
#360	HES1	9	17	26	716.051
#361	LHX8	9	6	15	259.198
#362	CBFA2T3	8	19	27	1002.64
#363	BCL6	8	15	23	537.027
#364	TGIF1	8	20	28	1842.607
#365	HOXB5	8	10	18	365.715
#366	SIM2	8	17	25	1136.668
#367	GATA4	8	5	13	329.528
#368	WT1	8	20	28	618.097
#369	MSX2	8	23	31	1360.88
#370	ZNF281	8	17	25	954.504
#371	HOXB3	8	4	12	182.496
#372	TFAP2B	8	25	33	804.729
#373	CCRN4L	8	22	30	2039.544
#374	TFAP2C	8	15	23	684.591
#375	GTF2H2	8	20	28	830.596
#376	PAX6	8	5	13	208.075
#377	AR	8	17	25	1196.692
#378	CEBPA	8	18	26	836.804
#379	RARB	8	14	22	1187.074
#380	MAX	8	8	16	182.821
#381	MSX1	8	20	28	1547.633
#382	MYCN	8	17	25	1063.908
#383	SOX12	8	15	23	781.948
#384	NFATC4	8	23	31	864.769
#385	GATA6	8	21	29	1250.408
#386	HOXB4	8	6	14	279.824
#387	ZNF496	8	18	26	876.174
#388	CUX2	8	15	23	1158.749
#389	ZNF83	8	19	27	804.797
#390	IRX4	7	18	25	781.287
#391	ZNF92	7	19	26	689.975
#392	TFAP2A	7	11	18	641.716
#393	FOXF2	7	8	15	286.628
#394	MTA1	7	18	25	638.865
#395	SIX4	7	16	23	758.32
#396	HMBOX1	7	20	27	1340.266
#397	OVOL1	7	22	29	1388.432
#398	CREM	7	19	26	1878.306
#399	ETV5	7	13	20	209.248
#400	NCOR1	7	13	20	1577.527
#401	NR2E3	7	18	25	1851.422
#402	CTBP1	7	25	32	1253.792
#403	ARNT	7	16	23	560.298
#404	ZNF167	7	15	22	827.673
#405	VAV1	7	12	19	1999.567
#406	TRERF1	7	19	26	1347.697
#407	NR2F1	7	23	30	545.684
#408	MESP1	7	16	23	800.416
#409	PITX1	7	27	34	2147.28
#410	ZFP90	7	18	25	531.891
#411	ESRRG	7	26	33	685.553
#412	TSC22D1	7	13	20	996.987
#413	GATA5	7	12	19	1399.126
#414	KLF3	7	14	21	627.093
#415	TRIM22	7	17	24	335.335
#416	SIX3	7	15	22	1130.446
#417	FOXC2	7	14	21	910.345
#418	STAT6	7	19	26	699.114
#419	HOXB13	7	15	22	578.281
#420	ISL1	7	12	19	472.01
#421	EN1	7	12	19	1056.261
#422	FOXQ1	7	14	21	2516.866
#423	ZNF274	7	15	22	881.556
#424	PBX3	7	25	32	1412.639
#425	ZSCAN16	6	21	27	1289.726
#426	NR1D2	6	12	18	341.373
#427	TBX1	6	21	27	665.178
#428	TEAD4	6	13	19	493.792
#429	TFDP1	6	22	28	1047.945
#430	ANKRD30A	6	22	28	926.353
#431	TP53	6	18	24	992.418
#432	NFATC1	6	18	24	1248.293
#433	SIX2	6	24	30	1189.332
#434	TCFL5	6	15	21	683.096
#435	KLF2	6	18	24	674.621
#436	NFE2L3	6	18	24	499.688
#437	TFDP2	6	14	20	503.218
#438	SREBF1	6	19	25	511.411
#439	VDR	6	18	24	1265.512
#440	CUX1	6	15	21	557.259
#441	ZNF70	6	12	18	272.723
#442	RORC	6	21	27	855.739
#443	FOXK1	6	18	24	529.903
#444	BATF	6	20	26	611.766
#445	ZNF165	6	21	27	639.795
#446	SOX9	6	23	29	867.055
#447	NFE2L2	6	18	24	878.965
#448	SIX1	6	26	32	776.691
#449	FOXK2	6	17	23	748.631
#450	HOXB8	6	10	16	376.329
#451	SLC30A9	6	17	23	735.285
#452	ZNF131	6	17	23	962.181
#453	FOXI1	6	27	33	1552.879
#454	SOX2	5	17	22	877.627
#455	PGBD1	5	14	19	673.798
#456	FOXC1	5	19	24	728.245
#457	LMO4	5	22	27	667.758
#458	MECOM	5	21	26	993.888
#459	TSC22D3	5	17	22	550.056
#460	MXD1	5	17	22	456.461
#461	ASCL1	5	25	30	656.383
#462	CDKN2A	5	18	23	566.5
#463	MBD1	5	15	20	569.69
#464	PPARA	5	19	24	687.064
#465	AHR	5	20	25	959.014
#466	TCF7L1	5	16	21	557.699
#467	SCML1	4	13	17	848.239
#468	MTA3	4	20	24	471.083
#469	CITED2	4	19	23	426.041
#470	PTH	4	5	9	132.023
#471	SREBF2	4	19	23	386.928
#472	ELF5	4	16	20	397.213
#473	ASCL2	4	23	27	500.425
#474	MITF	4	14	18	335.966
#475	MKX	4	22	26	1330.234
#476	C1orf85	4	16	20	383.853
#477	ZNF93	4	14	18	362.385
#478	GRHL3	4	21	25	265.866
#479	ZNF174	4	18	22	249.809
#480	CREB5	4	18	22	471.423
#481	IRF7	4	17	21	382.035
#482	CITED1	4	18	22	648.177
#483	TULP4	4	13	17	268.578
#484	DLX2	3	19	22	125.83
#485	LEF1	3	24	27	772.393
#486	ZNF91	3	19	22	238.007
#487	EHF	3	31	34	1023.158
#488	TAF7	3	15	18	1438.148
#489	HOXD10	3	16	19	445.646
#490	ELF3	2	24	26	209.406
#491	ATF5	2	18	20	784.883
#492	NR3C2	2	17	19	860.603
#493	HES6	2	19	21	155.025
#494	ZIC1	2	24	26	859.564
#495	MAFF	2	20	22	351.713
#496	POU2F3	2	18	20	239.624
#497	SOX6	2	23	25	187.493
#498	HEY1	1	14	15	65.464
#499	PGR	1	28	29	289.766
#500	IRF5	0	21	21	0