Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NR3C2	50	3	53	170.163
#2	KLF9	46	6	52	312.393
#3	SLC26A3	44	8	52	6667.617
#4	TEAD4	43	4	47	74.45
#5	MXD1	42	5	47	3257.776
#6	KLF4	41	2	43	37.968
#7	TCF4	37	5	42	921.682
#8	IRF6	37	5	42	349.589
#9	TGIF2	36	5	41	417.318
#10	NFE2L3	36	5	41	1334.188
#11	ISX	35	12	47	2028.782
#12	EGR1	35	5	40	208.224
#13	FOXM1	35	5	40	307.342
#14	MAFB	34	4	38	2277.412
#15	MYBL2	34	9	43	877.448
#16	SOX9	34	4	38	631.922
#17	HNF4G	32	5	37	112.458
#18	PROX1	32	6	38	100.755
#19	MYC	31	6	37	259.953
#20	SPIB	31	10	41	290.974
#21	NFAT5	30	7	37	563.512
#22	RB1	30	6	36	421.213
#23	ARID3A	30	13	43	1194.399
#24	NR1H4	29	7	36	765.753
#25	ETV4	29	8	37	2291.806
#26	WNT5A	28	6	34	330.995
#27	MEF2C	28	8	36	1161.821
#28	EHF	28	8	36	622.32
#29	FOXQ1	28	11	39	1037.702
#30	ASCL2	28	13	41	374.22
#31	HOPX	27	6	33	190.461
#32	ETV1	27	6	33	457.906
#33	ETS1	26	8	34	316.424
#34	CBFA2T3	26	5	31	2362.284
#35	STAT1	25	9	34	517.971
#36	MMP14	25	12	37	2621.766
#37	HSF1	25	9	34	328.363
#38	FOXA1	24	12	36	7214.018
#39	NFIC	24	11	35	1102.615
#40	AEBP1	24	5	29	288.595
#41	ZNF174	24	11	35	1101.721
#42	MEIS1	24	10	34	382.244
#43	SUPT6H	24	3	27	638.849
#44	PRRX1	23	4	27	396.946
#45	ZEB1	23	5	28	1152.25
#46	TP53	23	12	35	1525.005
#47	KLF16	22	12	34	891.131
#48	FOS	22	7	29	138.356
#49	TCF3	22	16	38	1460.061
#50	ZNF117	22	8	30	2682.611
#51	NR5A2	22	14	36	2425.427
#52	SOX4	21	11	32	345.53
#53	AHCTF1	21	11	32	1810.592
#54	FOXA2	21	12	33	600.231
#55	ZEB2	21	12	33	1109.879
#56	CDKN2A	21	8	29	1652.537
#57	FOXC1	21	15	36	835.854
#58	RARA	21	13	34	1540.677
#59	BCL6	21	15	36	879.43
#60	CREB3L1	21	8	29	1403.608
#61	ZNF3	20	13	33	507.456
#62	NR2F6	20	9	29	1483.966
#63	HOXA5	20	4	24	109.865
#64	SPDEF	20	7	27	154.303
#65	BHLHE40	20	10	30	301.612
#66	HES6	20	13	33	837.718
#67	ETV5	20	12	32	941.311
#68	HOXD4	20	16	36	2730.411
#69	OVOL1	20	10	30	1469.409
#70	FOXL1	20	13	33	1454.242
#71	SMAD2	20	13	33	1187.055
#72	HMGA1	20	12	32	613.595
#73	SIM2	19	8	27	3247.683
#74	HOXB6	19	12	31	2496.257
#75	NFIX	19	9	28	1345.156
#76	GRHL3	19	17	36	1104.434
#77	THRB	19	11	30	1723.46
#78	THRA	19	10	29	1010.003
#79	TCF7L2	19	15	34	1680.106
#80	ZNF277	19	10	29	1659.636
#81	IKZF4	19	9	28	1276.409
#82	SMAD9	19	9	28	265.754
#83	RUNX1T1	19	12	31	1452.983
#84	SLC2A4RG	18	13	31	1240.188
#85	HES5	18	12	30	1683.518
#86	FOXD1	18	13	31	1399.597
#87	NFIB	18	12	30	1033.364
#88	TFE3	18	9	27	260.466
#89	EGR2	18	10	28	1075.51
#90	RFX3	18	16	34	1004.232
#91	MAFK	18	14	32	2429.671
#92	ETV6	18	8	26	698.388
#93	MESP2	18	8	26	816.998
#94	MSX1	18	10	28	310.519
#95	SCAND2	18	14	32	1799.38
#96	HOXA1	17	15	32	1923.974
#97	CITED1	17	15	32	1247.543
#98	GLIS3	17	12	29	872.318
#99	BARX1	17	16	33	2212.946
#100	TCF12	17	12	29	1812.047
#101	TLX1	17	11	28	450.302
#102	NPAS1	17	13	30	1171.397
#103	SALL1	17	11	28	1841.249
#104	NPAS2	17	15	32	2139.893
#105	CREB5	17	17	34	1021.925
#106	ZNF154	17	9	26	1569.121
#107	HOXD11	16	7	23	474.987
#108	ATOH1	16	10	26	375.205
#109	TWIST1	16	5	21	225.126
#110	ZNF132	16	10	26	653.612
#111	HOXA9	16	4	20	273.387
#112	SMAD3	16	10	26	766.721
#113	FOXO3	16	13	29	720.492
#114	HOXA7	16	5	21	538.981
#115	GATA5	16	16	32	1955.206
#116	NFE2	16	11	27	993.779
#117	MEOX1	16	13	29	1275.791
#118	KLF1	16	9	25	1031.68
#119	FOXS1	16	14	30	367.137
#120	HOXD10	16	6	22	670.903
#121	TCF21	16	13	29	1326.794
#122	CTNNB1	16	15	31	1199.429
#123	ZNF92	16	7	23	248.14
#124	RARB	16	11	27	1100.847
#125	ZNF238	15	10	25	636.005
#126	FOSL2	15	6	21	338.095
#127	TEF	15	11	26	403.529
#128	CSDA	15	15	30	1461.887
#129	STRN3	15	17	32	2060.959
#130	HNF1B	15	12	27	1744
#131	TBX3	15	10	25	1136.346
#132	DLX1	15	10	25	646.64
#133	ZFPM2	15	10	25	874.345
#134	YY1	15	14	29	714.438
#135	ISL1	15	11	26	982.94
#136	ZNF93	15	10	25	983.505
#137	BACH2	15	14	29	1601.342
#138	TFEC	15	15	30	1810.031
#139	EMX1	15	12	27	753.896
#140	CREM	15	13	28	1835.298
#141	RORC	15	12	27	882.053
#142	LEF1	15	16	31	2108.196
#143	ETS2	15	11	26	2580.913
#144	PLAG1	15	13	28	3819.282
#145	NR4A1	15	5	20	91.298
#146	HOXB8	15	15	30	1153.195
#147	SMAD1	14	12	26	2881.64
#148	ZNF449	14	8	22	720.037
#149	FOSL1	14	12	26	456.733
#150	NR4A2	14	7	21	469.445
#151	TBX22	14	16	30	2517.68
#152	HOXD3	14	15	29	1776.569
#153	CRX	14	11	25	741.376
#154	ZNF70	14	14	28	1241.369
#155	SEBOX	14	14	28	1935.204
#156	LHX9	14	12	26	1141.876
#157	DMBX1	14	14	28	1955.258
#158	PITX1	14	10	24	918.394
#159	STAT5B	14	19	33	1673.75
#160	VTN	14	16	30	1444.303
#161	TRPS1	14	12	26	551.433
#162	SOX13	14	11	25	693.197
#163	ZSCAN18	14	14	28	1552.035
#164	NFATC2	14	12	26	761.089
#165	TRERF1	14	17	31	1620.587
#166	TULP4	13	16	29	1423.342
#167	TRIM29	13	10	23	1005.429
#168	TBX6	13	10	23	897.147
#169	GSX2	13	10	23	857.666
#170	NR5A1	13	17	30	1938.015
#171	NRL	13	14	27	1965.588
#172	HEY1	13	16	29	1470.861
#173	IRX4	13	11	24	1152.481
#174	GAS7	13	13	26	668.787
#175	SIX1	13	14	27	1284.553
#176	POU2F2	13	14	27	1574.749
#177	ZIC5	13	15	28	975.285
#178	HOXA10	13	10	23	792.023
#179	TFAP2A	13	18	31	1718.545
#180	ZNF134	13	16	29	1561.503
#181	FUBP1	13	19	32	1847.947
#182	IRX3	13	14	27	504.411
#183	PBX1	13	14	27	1256.768
#184	ELK3	13	16	29	1126.137
#185	POU2F3	13	16	29	1464.232
#186	MAF	13	18	31	2473.677
#187	ZNF155	13	10	23	1194.065
#188	ZBTB48	13	12	25	924.181
#189	MLXIPL	13	11	24	868.843
#190	RFXAP	13	12	25	1464.646
#191	RUNX3	13	15	28	2295.425
#192	FOXK1	13	18	31	2297.568
#193	RERE	13	13	26	1111.576
#194	CNOT7	13	11	24	952.518
#195	DLX3	13	16	29	1068.302
#196	TSHZ2	13	18	31	1719.266
#197	ZNF85	13	13	26	1239.465
#198	SCAND1	13	13	26	546.004
#199	ATF6B	13	11	24	412.044
#200	GBX2	13	12	25	1259.966
#201	TAL1	13	17	30	1997.31
#202	E2F2	12	15	27	1151.548
#203	POU4F2	12	15	27	1338.81
#204	SNAPC5	12	12	24	1336.959
#205	SOX18	12	13	25	674.494
#206	NKX6-1	12	17	29	1338.609
#207	CSRNP3	12	15	27	1140.676
#208	GATAD2A	12	14	26	1409.93
#209	MKX	12	13	25	655.479
#210	PGBD1	12	14	26	1332.862
#211	MECOM	12	14	26	1434.871
#212	REST	12	12	24	1330.546
#213	MITF	12	12	24	1655.528
#214	TCF20	12	16	28	961.093
#215	HOXA2	12	10	22	411.853
#216	ZNF215	12	11	23	1206.709
#217	ATF2	12	21	33	1782.13
#218	SOX5	12	14	26	1253.096
#219	TFCP2L1	12	13	25	847.175
#220	ONECUT1	12	12	24	1362.377
#221	BATF	12	16	28	1698.317
#222	GSX1	12	13	25	1173.338
#223	ONECUT2	12	18	30	1627.889
#224	HOXC12	12	7	19	648.927
#225	ESRRG	12	15	27	916.454
#226	HLF	12	10	22	685.701
#227	ZIC1	11	13	24	1492.793
#228	LMO4	11	15	26	1172.422
#229	ZNF483	11	17	28	1279.961
#230	HNRNPAB	11	9	20	1066.699
#231	DLX2	11	14	25	1138.188
#232	FOXP1	11	15	26	577.901
#233	FOXP2	11	13	24	2934.587
#234	ISL2	11	22	33	1373.518
#235	SNAI3	11	13	24	1563.211
#236	SMAD4	11	15	26	1575.271
#237	ENO1	11	13	24	756.479
#238	ARX	11	14	25	576.577
#239	GATA4	11	15	26	1523.774
#240	MBD1	11	8	19	598.626
#241	TAF4	11	13	24	1095.332
#242	NR2E1	11	12	23	1060.788
#243	MTA2	11	14	25	892.652
#244	KLF15	11	12	23	1319.491
#245	NR6A1	11	15	26	1588.486
#246	HOXC11	11	9	20	1283.957
#247	ETV7	11	11	22	1080.738
#248	CREBBP	11	14	25	1329.176
#249	HOXC9	11	9	20	1498.279
#250	ALX1	11	19	30	1231.144
#251	TAF10	11	8	19	996.874
#252	KDM5B	11	11	22	1467.272
#253	SOX12	11	12	23	841.879
#254	HDX	11	11	22	1049.713
#255	DMRT1	11	14	25	1506.494
#256	MSX2	11	18	29	5326.544
#257	ZNF287	11	12	23	934.09
#258	FOXE3	11	8	19	529.977
#259	SOX1	10	15	25	1383.306
#260	PPARA	10	12	22	807.945
#261	PAX8	10	15	25	976.469
#262	PDX1	10	10	20	520.509
#263	FOXH1	10	13	23	1145.914
#264	CBL	10	18	28	786.598
#265	ARNT	10	14	24	1109.145
#266	RUNX1	10	15	25	947.22
#267	TWIST2	10	11	21	1396.142
#268	FOXI1	10	9	19	1266.955
#269	HOXA13	10	9	19	675.039
#270	FOSB	10	7	17	687.562
#271	ZNF131	10	14	24	1131.67
#272	SIX2	10	17	27	1809.721
#273	VENTX	10	14	24	969.592
#274	TLX3	10	11	21	1029.522
#275	WT1	10	17	27	838.916
#276	ESX1	10	13	23	944.696
#277	FOXJ1	10	13	23	1957.922
#278	ZSCAN20	10	15	25	998.863
#279	HOXA11	10	14	24	687.342
#280	BRD8	10	18	28	1197.927
#281	ST18	10	20	30	1265.367
#282	TEAD2	10	12	22	386.191
#283	POU3F3	10	12	22	973.326
#284	MYF5	10	11	21	914.051
#285	ZNF256	10	13	23	1079.891
#286	TADA2A	10	10	20	346.34
#287	CREB3L3	10	13	23	997.796
#288	NPAT	10	15	25	1181.218
#289	MYOG	10	12	22	686.781
#290	MZF1	10	11	21	345.541
#291	TFAP2C	10	16	26	2003.819
#292	NCOR1	10	15	25	737.788
#293	NFKB2	10	14	24	1552.954
#294	HOXD9	10	12	22	976.959
#295	TSC22D2	10	15	25	1023.888
#296	HOXA4	10	12	22	559.433
#297	MYT1L	10	14	24	1554.639
#298	FOXC2	10	12	22	1093.744
#299	MESP1	10	18	28	1878.259
#300	FOXE1	10	16	26	2138.838
#301	MYCN	10	15	25	1053.619
#302	RCAN1	10	13	23	797.757
#303	MLL	10	13	23	1364.23
#304	TGIF2LY	10	15	25	1078.35
#305	ASCL1	10	11	21	775.938
#306	HOXD1	9	10	19	820.205
#307	ZSCAN10	9	13	22	1041.074
#308	TAF1B	9	8	17	309.385
#309	IRF4	9	5	14	180.821
#310	NFYA	9	9	18	864.472
#311	LASS5	9	11	20	990.462
#312	PAX6	9	16	25	1000.507
#313	PPARD	9	13	22	787.853
#314	RORA	9	18	27	1406.693
#315	DMRT2	9	16	25	1519.088
#316	AFF4	9	10	19	548.122
#317	SOX2	9	20	29	1085.449
#318	ZNF175	9	19	28	2483.437
#319	NR1I3	9	12	21	664.739
#320	SIN3A	9	13	22	1042.608
#321	ERG	9	12	21	734.397
#322	KLF12	9	15	24	1114.581
#323	ZSCAN4	9	14	23	1018.593
#324	IRX5	9	10	19	816.364
#325	GCM1	9	12	21	930.544
#326	HIRA	9	11	20	752.621
#327	CTBP1	9	9	18	415.89
#328	SREBF1	9	15	24	1543.23
#329	NANOGNB	9	14	23	918.723
#330	POU2F1	9	19	28	1642.822
#331	RUNX2	9	9	18	437.198
#332	ZXDC	9	10	19	539.887
#333	CREBZF	9	14	23	690.839
#334	PHF1	9	14	23	1157.779
#335	HEY2	9	12	21	535.166
#336	LHX2	8	14	22	738.55
#337	HOXB13	8	15	23	904.005
#338	HOXD13	8	14	22	1117.458
#339	MEOX2	8	16	24	941.05
#340	DLX6	8	14	22	650.431
#341	NR4A3	8	15	23	833.471
#342	LHX8	8	17	25	1143.823
#343	SOX11	8	14	22	505.747
#344	EN2	8	11	19	1025.228
#345	OTX2	8	14	22	954.353
#346	FOXD3	8	16	24	922.809
#347	ZNF80	8	16	24	1036.259
#348	EBF1	8	15	23	948.178
#349	NEUROD1	8	15	23	2747.661
#350	L3MBTL4	8	15	23	1068.958
#351	POU6F2	8	14	22	1391.322
#352	SIX4	8	17	25	992.3
#353	ZNF90	8	11	19	1600.835
#354	HSF5	8	14	22	1050.635
#355	LMX1A	8	12	20	1339.112
#356	ZNF135	8	17	25	760.119
#357	VSX1	8	15	23	655.568
#358	TBX2	8	14	22	981.957
#359	TADA3	8	13	21	994.035
#360	POU3F2	8	11	19	675.508
#361	ELK1	8	14	22	456.312
#362	ZNF24	8	11	19	1175.165
#363	GATA3	8	12	20	588.058
#364	ESRRB	8	16	24	1309.028
#365	TBX5	8	9	17	567.428
#366	FOXL2	8	15	23	1177.72
#367	GSC2	8	11	19	510.267
#368	TBX20	8	12	20	943.783
#369	ZSCAN1	8	13	21	1152.919
#370	MYT1	8	14	22	1057.874
#371	ZNF81	8	16	24	1703.652
#372	SIX6	8	17	25	986.199
#373	RARG	8	13	21	1046.614
#374	ZNF496	8	14	22	1152.607
#375	POU5F2	8	14	22	677.678
#376	GATAD1	8	8	16	512.542
#377	KDM5A	8	13	21	912.335
#378	HMG20B	8	12	20	681.53
#379	NEUROD2	8	12	20	525.961
#380	HIC1	8	15	23	837.902
#381	C11orf9	8	13	21	1258.135
#382	FOXN4	8	12	20	400.385
#383	PKNOX2	8	12	20	394.556
#384	ELF5	7	18	25	5067.242
#385	ZFP36L1	7	11	18	480.941
#386	ZNF207	7	15	22	1177.041
#387	FOXO1	7	11	18	1032.961
#388	SOX6	7	11	18	729.006
#389	HCFC1	7	11	18	487.763
#390	ANKRD30A	7	19	26	1139.922
#391	POU4F1	7	15	22	1077.41
#392	ZIC2	7	21	28	1228.594
#393	ZNF397	7	12	19	674.476
#394	NR0B1	7	21	28	1266.464
#395	GATA1	7	12	19	1015.819
#396	ZKSCAN3	7	18	25	1025.282
#397	SIM1	7	18	25	1094.392
#398	FLI1	7	14	21	793.088
#399	TBR1	7	12	19	835.611
#400	PAX4	7	11	18	1051.194
#401	PAX7	7	18	25	978.028
#402	ELK4	7	13	20	1067.908
#403	GLI3	7	14	21	718.629
#404	CUX2	7	17	24	863.128
#405	NKX2-1	7	14	21	563.806
#406	SOX30	7	15	22	1371.184
#407	ZFHX3	7	15	22	741.832
#408	PAX3	7	18	25	1177.326
#409	ALX4	7	16	23	679.102
#410	MLLT10	7	12	19	723.431
#411	TSC22D3	7	14	21	883.925
#412	BCL11B	7	12	19	1400.583
#413	TP73	7	17	24	848.611
#414	RXRG	7	16	23	832.567
#415	HESX1	7	15	22	503.549
#416	IKZF3	7	19	26	1034.019
#417	POU3F4	7	13	20	766.502
#418	LZTS1	7	13	20	1120.877
#419	MIXL1	7	13	20	826.901
#420	BACH1	7	13	20	812.533
#421	PEG3	7	15	22	781.395
#422	ALS2CR8	7	12	19	607.053
#423	ZNF167	7	14	21	562.851
#424	MYF6	7	14	21	813.342
#425	ZFP42	6	19	25	1416.542
#426	OLIG2	6	14	20	796.108
#427	EGR4	6	12	18	389.381
#428	FOXP3	6	12	18	739.295
#429	PHOX2B	6	12	18	717.83
#430	NFATC1	6	14	20	642.955
#431	IKZF1	6	12	18	385.582
#432	ZNF639	6	17	23	766.916
#433	NANOG	6	15	21	865.046
#434	EN1	6	15	21	724.149
#435	SOX10	6	18	24	830.432
#436	ESR1	6	14	20	654.767
#437	ZNF169	6	11	17	567.566
#438	BLZF1	6	11	17	772.079
#439	IRX1	6	12	18	429.407
#440	PBX3	6	12	18	858.325
#441	RBPJ	6	14	20	880.369
#442	FOXK2	6	18	24	1030.531
#443	C2orf3	6	12	18	682.01
#444	ZNF71	6	13	19	402.683
#445	NFIA	6	18	24	912.675
#446	TFAP2B	6	7	13	190.639
#447	ESR2	6	17	23	689.896
#448	SPIC	6	12	18	973.364
#449	HIF3A	6	15	21	615.526
#450	BHLHE41	6	14	20	705.299
#451	SCAND3	6	19	25	963.202
#452	TFAP4	6	14	20	657.531
#453	ZHX3	6	12	18	797.879
#454	POU1F1	6	17	23	889.696
#455	TFDP3	6	15	21	566.183
#456	SP140	5	12	17	561.427
#457	ARNT2	5	16	21	582.648
#458	NR2E3	5	18	23	835.009
#459	IRX2	5	19	24	979.25
#460	TP63	5	16	21	414.249
#461	ZSCAN2	5	12	17	457.254
#462	POU3F1	5	14	19	486.023
#463	PLSCR1	5	9	14	704.473
#464	NKX2-8	5	13	18	858.846
#465	SIX3	5	17	22	586.001
#466	TBX1	5	17	22	812.528
#467	FOXR2	5	11	16	401.535
#468	FOXG1	5	20	25	1785.545
#469	TAF13	5	12	17	561.428
#470	ZNF396	5	14	19	521.347
#471	RCOR1	5	11	16	304.537
#472	ZNF157	5	16	21	500.309
#473	RORB	5	17	22	1406.562
#474	ZFHX4	5	18	23	719.354
#475	TBX15	5	19	24	696.011
#476	ZSCAN23	5	14	19	733.22
#477	NOBOX	5	13	18	701.925
#478	SOX8	4	16	20	906.939
#479	PGR	4	13	17	730.775
#480	JUND	4	16	20	632.623
#481	CEBPE	4	16	20	560.007
#482	PTH	4	14	18	423.295
#483	HR	4	16	20	359.734
#484	SMAD6	4	8	12	763.639
#485	ZIC3	4	20	24	727.333
#486	PRDM2	4	14	18	373.918
#487	MYNN	4	15	19	503.662
#488	NKX6-2	4	14	18	199.561
#489	BNC1	4	11	15	354.041
#490	TLX2	4	14	18	401.265
#491	C12orf28	3	14	17	451.539
#492	IRF5	3	16	19	830.602
#493	KLF17	3	13	16	487.133
#494	MGA	3	16	19	351.339
#495	HMGA2	3	15	18	532.948
#496	GLI2	3	20	23	447.888
#497	SOX21	2	14	16	106.455
#498	ZSCAN12	2	20	22	255.999
#499	HNF4A	1	15	16	50.177
#500	ARNTL2	1	14	15	104.39