Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZC3H8	103	4	107	368.394
#2	IRF6	67	1	68	1328.21
#3	SOX2	63	6	69	477.519
#4	TP63	62	3	65	1763.348
#5	FLI1	62	1	63	5595.356
#6	RORC	60	8	68	9713.861
#7	C5orf41	57	2	59	68.401
#8	ZNF639	54	8	62	1390.685
#9	NKX2-1	52	6	58	369.467
#10	SNAI2	50	14	64	407.854
#11	FOXM1	50	5	55	888.071
#12	TRIM29	49	2	51	55.987
#13	CSDA	49	8	57	492.202
#14	E2F7	48	9	57	254.874
#15	FOXE1	47	2	49	13.998
#16	MYC	47	8	55	382.053
#17	ATF1	46	1	47	32.698
#18	LASS6	45	11	56	697.824
#19	MEF2C	44	8	52	3630.819
#20	ZNF367	44	10	54	364.124
#21	ARNTL2	44	11	55	657.349
#22	ZFHX3	43	14	57	1927.37
#23	GRHL3	43	6	49	846.929
#24	KLF5	42	11	53	5115.828
#25	MYNN	41	7	48	226.37
#26	FOXP1	41	8	49	742.784
#27	CREB3L1	40	9	49	150.425
#28	CITED2	40	18	58	2722.104
#29	NFIA	40	7	47	809.59
#30	HNF1B	40	12	52	267.466
#31	SOX15	40	8	48	98.887
#32	MLX	39	5	44	192.23
#33	IKZF1	38	5	43	160.01
#34	GLI2	38	9	47	295.093
#35	ZEB2	38	3	41	124.738
#36	MYBL2	37	7	44	122.726
#37	IRF8	37	4	41	3148.281
#38	SPDEF	37	9	46	159.182
#39	NOLC1	36	6	42	178.012
#40	CNOT8	36	11	47	3090.858
#41	DLX6	36	6	42	571.38
#42	BNC1	35	6	41	92.845
#43	PRDM1	34	8	42	2169.797
#44	FOXA2	33	16	49	441.275
#45	DMRT2	33	7	40	76.704
#46	PITX1	33	14	47	189.864
#47	NFIX	33	14	47	1154.154
#48	UHRF1	33	5	38	37.201
#49	HR	32	10	42	583.735
#50	TFAP2C	32	16	48	1204.189
#51	ETS1	32	8	40	498.678
#52	HDAC2	32	13	45	889.326
#53	KLF2	32	3	35	208.126
#54	TGIF2	32	15	47	2670.755
#55	ZSCAN16	31	9	40	695.31
#56	ZEB1	30	11	41	586.111
#57	TAF4B	30	18	48	2784.281
#58	CSRNP1	30	9	39	1677.737
#59	BCL11B	30	19	49	939.019
#60	GABPB1	30	11	41	815.861
#61	CREB1	29	4	33	1596.646
#62	STAT1	29	10	39	865.474
#63	TCF21	29	8	37	678.598
#64	CREB3L2	29	14	43	1248.592
#65	TCF4	29	16	45	1822.397
#66	PURA	29	11	40	593.79
#67	FOXO1	28	11	39	673.711
#68	YBX1	28	9	37	972.186
#69	SOX4	28	12	40	1053.733
#70	ENO1	28	14	42	3199.818
#71	GTF2IRD1	28	15	43	1537.449
#72	NFE2L2	27	15	42	3101.967
#73	HOPX	27	19	46	2103.386
#74	VDR	27	19	46	3069.041
#75	TBX5	27	12	39	1344.414
#76	SALL2	27	14	41	1164.602
#77	MXD1	27	14	41	782.688
#78	ASCL2	27	22	49	4559.808
#79	LEF1	27	14	41	1867.793
#80	GTF2H2	27	9	36	273.217
#81	STAT4	27	12	39	2027.992
#82	LMO4	26	16	42	1485.383
#83	SP140	26	2	28	33.266
#84	HMGA1	26	15	41	885.409
#85	FOXP4	26	12	38	1423.119
#86	EBF1	25	13	38	1548.736
#87	TRIM22	25	12	37	1938.971
#88	PBX1	25	27	52	5894.301
#89	NFYB	25	10	35	2209.989
#90	EGR3	25	7	32	780.301
#91	NFIL3	25	11	36	4170.837
#92	SP1	25	4	29	153.876
#93	TFDP2	25	14	39	1124.035
#94	NR2F6	25	17	42	2117.465
#95	MEOX2	24	4	28	12233.207
#96	ZNF238	24	12	36	3554.064
#97	RERE	24	6	30	320.154
#98	GATA3	24	18	42	2701.824
#99	GLIS2	24	17	41	1538.851
#100	MTA3	24	13	37	957.406
#101	IRX3	23	16	39	748.953
#102	ZNF277	23	9	32	1315.212
#103	JUNB	23	10	33	1177.37
#104	HES1	23	17	40	1568.013
#105	ELF4	23	10	33	2243.05
#106	GRHL2	23	14	37	1280.3
#107	TEAD4	23	12	35	566.414
#108	ZNF117	23	14	37	898.976
#109	TSC22D3	23	16	39	2773.515
#110	GTF2I	23	6	29	127.799
#111	MITF	23	20	43	3836.259
#112	NFIC	22	13	35	904.771
#113	LASS2	22	13	35	821.584
#114	PAX6	22	16	38	2931.099
#115	KLF12	22	10	32	1039.623
#116	WNT5A	22	11	33	298.189
#117	IRF7	22	11	33	1405.652
#118	SMAD4	22	15	37	1053.887
#119	FOXD1	22	15	37	527.637
#120	ZIC2	22	18	40	6388.007
#121	NR3C2	22	17	39	1007.996
#122	ELK3	21	17	38	1345.754
#123	TCF19	21	14	35	3179.042
#124	GAS7	21	12	33	1720.295
#125	GLIS3	21	17	38	829.653
#126	E2F8	20	14	34	976.428
#127	HOXB3	20	15	35	2367.159
#128	DLX1	20	12	32	4036.613
#129	CBL	20	6	26	1540.06
#130	NFYA	20	17	37	2318.567
#131	ZNF167	20	16	36	2327.048
#132	EN1	20	21	41	6880.703
#133	BATF	20	23	43	4182.9
#134	TCF25	20	12	32	808.955
#135	HOXD13	20	13	33	1189.574
#136	NFATC1	20	21	41	1405.279
#137	GATA6	20	19	39	1955.592
#138	PCGF6	20	16	36	905.803
#139	FOXO6	20	15	35	2712.875
#140	TCF7	20	14	34	978.484
#141	ZFP36L2	19	10	29	1954.269
#142	CREBL2	19	11	30	1195.016
#143	ZNF83	19	18	37	1054.154
#144	MAX	19	10	29	639.375
#145	TFCP2	19	11	30	1542.446
#146	NR2F1	19	17	36	381.49
#147	KLF4	18	15	33	1371.592
#148	RUNX1	18	12	30	802.767
#149	ETV6	18	10	28	298.739
#150	MEIS1	18	22	40	1165.156
#151	PKNOX2	18	13	31	4906.919
#152	ZNF33A	18	18	36	1247.498
#153	PLAGL2	18	11	29	175.154
#154	TRIM28	18	15	33	1452.251
#155	ZNF133	18	14	32	1421.002
#156	MGA	18	4	22	334.664
#157	RELB	18	15	33	1084.107
#158	HCLS1	17	12	29	470.374
#159	GATAD2A	17	16	33	2044.337
#160	YEATS4	17	15	32	1372.336
#161	FOSL1	17	17	34	1419.795
#162	EOMES	17	11	28	450.048
#163	SIX1	17	15	32	898.91
#164	TULP4	17	12	29	634.966
#165	FOSL2	17	15	32	674.503
#166	GABPA	17	10	27	606.821
#167	EHF	17	16	33	891.776
#168	SOX12	17	14	31	1173.969
#169	TFDP1	17	17	34	7132.631
#170	ZNF148	17	13	30	2077.615
#171	NR3C1	17	18	35	4079.143
#172	NR4A1	17	2	19	19.779
#173	ZIC1	17	20	37	1703.253
#174	NFYC	17	8	25	1995.941
#175	SOX17	17	8	25	524.147
#176	TWIST1	17	17	34	380.365
#177	IRX5	17	16	33	1352.626
#178	PCGF2	16	17	33	565.359
#179	FUBP1	16	11	27	1901.787
#180	ZFPM2	16	11	27	1939.615
#181	HOXA9	16	15	31	2125.038
#182	UBN1	16	7	23	386.543
#183	CBFA2T2	16	16	32	2139.063
#184	NOTCH1	16	21	37	2102.386
#185	PA2G4	16	14	30	778.751
#186	KLF3	16	12	28	614.489
#187	AEBP1	16	6	22	329.364
#188	HEY1	16	15	31	235.822
#189	SOX7	16	16	32	1071.071
#190	SPEN	16	2	18	168.551
#191	ZNF187	16	15	31	1752.594
#192	MAFK	16	19	35	1088.999
#193	POU2F3	15	13	28	3957.349
#194	MYCL1	15	20	35	1154.569
#195	RUNX1T1	15	13	28	1723.677
#196	POU3F2	15	12	27	1057.329
#197	MAFG	15	14	29	342.913
#198	KDM5B	15	18	33	708.754
#199	AHR	15	20	35	1700.716
#200	DLX2	15	15	30	3780.703
#201	NFKB2	15	12	27	794.11
#202	SIM2	15	17	32	1879.433
#203	JDP2	15	16	31	1435.011
#204	PPARD	15	23	38	603.771
#205	FOXP2	14	20	34	465.344
#206	HOXD10	14	12	26	324.965
#207	HMGA2	14	23	37	808.644
#208	ZFHX4	14	24	38	2430.502
#209	HSF1	14	13	27	3834.299
#210	CUX1	14	12	26	409.899
#211	SPIC	14	7	21	916.297
#212	HEYL	14	15	29	575.137
#213	ZKSCAN1	14	18	32	1437.756
#214	HOXA1	14	17	31	9965.245
#215	HOXD11	14	12	26	2570.387
#216	SMAD3	14	21	35	7934.085
#217	SMAD6	14	19	33	1019.391
#218	TFAP2A	14	19	33	1174.6
#219	BHLHE41	14	19	33	1328.848
#220	RFX5	14	10	24	369.144
#221	ZNF131	14	19	33	296.431
#222	C1orf85	14	17	31	1552.745
#223	FOSB	14	3	17	15.651
#224	MEIS3P1	14	21	35	1280.216
#225	FOS	14	11	25	2267.241
#226	ZNF91	14	17	31	413.291
#227	FOXI1	14	5	19	520.067
#228	HHEX	14	18	32	2101.998
#229	KLF15	13	23	36	685.282
#230	BCL6	13	16	29	461.555
#231	VAV1	13	17	30	1126.003
#232	ETV5	13	21	34	1519.373
#233	GTF2H4	13	12	25	712.365
#234	NFATC2	13	15	28	3372.741
#235	RXRA	13	24	37	1815.477
#236	TFEB	13	19	32	686.398
#237	IRF4	13	4	17	12.36
#238	ZGPAT	13	23	36	1451.053
#239	TFAM	13	12	25	511.074
#240	SATB1	13	21	34	2386.228
#241	FOXO3	13	20	33	5065.012
#242	ZHX2	13	21	34	1410.612
#243	PBX3	13	17	30	2109.133
#244	RXRB	13	16	29	562.509
#245	HMGB2	13	15	28	503.418
#246	TFEC	13	10	23	704.149
#247	ZNF70	13	18	31	1359.381
#248	MECOM	13	25	38	1681.514
#249	MAFB	13	15	28	422.865
#250	TCF7L2	12	14	26	449.807
#251	ATF2	12	15	27	700.789
#252	NFAT5	12	6	18	79.851
#253	SIX3	12	15	27	2327.349
#254	TCF12	12	13	25	2178.657
#255	MSC	12	14	26	1095.654
#256	MBD1	12	17	29	2258.355
#257	CEBPA	12	16	28	868.873
#258	SLC30A9	12	23	35	1580.282
#259	SIX4	12	15	27	348.146
#260	RORA	12	20	32	1013.061
#261	OTX2	12	9	21	692.601
#262	HOXD1	12	14	26	901.945
#263	BTG2	12	17	29	745.087
#264	FOXN3	12	22	34	961.404
#265	MSX2	12	19	31	3689.047
#266	ZFP36L1	12	15	27	1013.743
#267	NR0B1	12	20	32	5047.291
#268	CTNNB1	12	19	31	792.399
#269	TFAP2B	12	15	27	2406.195
#270	TSHZ3	12	17	29	516.722
#271	ZNF496	12	17	29	948.455
#272	BHLHE40	12	14	26	851.814
#273	NR2F2	12	21	33	904.28
#274	GATAD2B	11	17	28	607.127
#275	NR4A3	11	8	19	203.534
#276	E2F3	11	14	25	1853.055
#277	BCL3	11	11	22	1381.238
#278	PEG3	11	20	31	14937.349
#279	ZNF93	11	19	30	5205.79
#280	OVOL1	11	14	25	316.828
#281	SIX2	11	19	30	1115.418
#282	ZFP42	11	14	25	636.566
#283	ZNF256	11	20	31	2005.85
#284	HIC1	11	14	25	858.916
#285	PLSCR1	11	14	25	876.279
#286	ERG	11	15	26	1024.366
#287	STAT6	11	10	21	1166.312
#288	FOXA1	11	16	27	1363.426
#289	SCMH1	11	12	23	617.232
#290	ETV1	11	14	25	188.328
#291	MESP1	11	16	27	1333.768
#292	PTTG1	11	12	23	674.471
#293	KLF10	11	15	26	733.212
#294	E2F6	11	15	26	649.174
#295	ATF3	11	8	19	861.212
#296	TBX1	10	25	35	1076.379
#297	TBX2	10	15	25	775.111
#298	MAF	10	17	27	1793.549
#299	RUNX3	10	19	29	879.492
#300	CREB3L4	10	20	30	1502.481
#301	E2F5	10	16	26	708.045
#302	NFATC3	10	22	32	1372.701
#303	ATF6	10	15	25	3119.79
#304	REL	10	17	27	1332.241
#305	TAF12	10	15	25	2007.174
#306	PHF5A	10	13	23	109.949
#307	CREM	10	19	29	582.367
#308	TAF5	10	18	28	463.617
#309	SOX6	10	18	28	462.448
#310	ZFP90	10	16	26	891.79
#311	PURB	10	18	28	1274.083
#312	LHX8	10	9	19	495.461
#313	FOXG1	10	14	24	3586.527
#314	NR1H3	10	16	26	553.177
#315	ZFPM1	10	21	31	1781.535
#316	CEBPD	10	17	27	1718.068
#317	NR5A2	10	17	27	4164.117
#318	PROX1	9	16	25	449.259
#319	NKX2-3	9	12	21	827.048
#320	RUNX2	9	18	27	1209.584
#321	KLF6	9	21	30	729.171
#322	HOXB6	9	14	23	305.354
#323	FOXA3	9	19	28	609.655
#324	BACH2	9	14	23	415.901
#325	FOXJ1	9	16	25	247.729
#326	TRPS1	9	19	28	3553.421
#327	PITX2	9	24	33	1241.114
#328	C11orf9	9	18	27	377.854
#329	TAF1B	9	13	22	500.207
#330	RB1	9	21	30	1741.267
#331	ZSCAN18	9	26	35	1047.272
#332	BATF3	9	26	35	856.007
#333	ZNF75D	9	19	28	666.809
#334	TARDBP	9	21	30	494.487
#335	L3MBTL4	9	19	28	3625.169
#336	FOXK1	9	18	27	533.542
#337	ELF1	9	19	28	947.038
#338	ZNF3	9	22	31	1515.63
#339	MLLT10	9	20	29	1939.902
#340	ZNF92	9	21	30	1032.023
#341	EPAS1	9	18	27	915.227
#342	C2orf3	8	18	26	333.601
#343	MSX1	8	17	25	860.971
#344	PRRX1	8	14	22	2154.8
#345	NFXL1	8	24	32	1220.608
#346	SOX13	8	19	27	1979.122
#347	HOXC4	8	14	22	739.867
#348	MEF2A	8	24	32	3374.848
#349	GTF2H3	8	17	25	1028.867
#350	NR4A2	8	10	18	794.986
#351	MLL	8	14	22	421.746
#352	RELA	8	24	32	1528.08
#353	SOLH	8	14	22	1113.323
#354	SIN3A	8	20	28	2286.909
#355	KLF9	8	17	25	2311.402
#356	PPARG	8	25	33	3021.772
#357	EGR2	8	15	23	335.964
#358	CNOT7	8	15	23	1190.737
#359	SPIB	8	12	20	753.805
#360	SREBF2	8	14	22	124.835
#361	KLF7	8	24	32	1216.673
#362	MEIS2	8	26	34	790.513
#363	PGR	8	16	24	1006.115
#364	ESR1	8	22	30	2872.066
#365	ARNT	8	20	28	434.813
#366	TCF7L1	7	26	33	1111.683
#367	CREB3	7	19	26	2010.813
#368	TEF	7	28	35	753.654
#369	LHX2	7	21	28	2759.694
#370	BARX1	7	15	22	642.599
#371	ZBTB38	7	11	18	2569.323
#372	ADNP	7	21	28	1351.329
#373	POU2F2	7	5	12	315.054
#374	ARX	7	27	34	532.048
#375	KLF11	7	20	27	2333.006
#376	PBX2	7	15	22	2086.035
#377	TAF5L	7	21	28	758.509
#378	FOXC2	7	20	27	2679.274
#379	RBCK1	7	22	29	766.531
#380	ZNF274	7	19	26	863.703
#381	IRF1	7	12	19	101.532
#382	FOXF2	7	19	26	725.748
#383	JUN	7	14	21	520.273
#384	BATF2	7	17	24	1537.481
#385	HLF	7	19	26	1037.448
#386	ATF7	7	19	26	506.778
#387	NFIB	7	26	33	3498.675
#388	SMAD1	6	24	30	704.455
#389	TRIM25	6	19	25	450.171
#390	HOXA5	6	18	24	480.08
#391	SLC2A4RG	6	21	27	460.178
#392	GLI3	6	25	31	619.469
#393	FBXW7	6	22	28	929.614
#394	PRRX2	6	17	23	302.524
#395	TFAP2D	6	14	20	5391.432
#396	XBP1	6	19	25	470.563
#397	HOXD8	6	20	26	1421.437
#398	CBFB	6	11	17	123.6
#399	HES6	6	22	28	989.28
#400	JUND	6	14	20	783.197
#401	DDIT3	6	25	31	1340.183
#402	ZNF397	6	21	27	974.543
#403	VTN	6	4	10	624.244
#404	IRX2	6	25	31	268.042
#405	IKZF4	6	19	25	1065.467
#406	SALL1	6	15	21	1139.398
#407	ZNF323	6	25	31	464.769
#408	SMAD2	6	23	29	1249.522
#409	ZNF138	6	17	23	711.546
#410	MTA1	6	18	24	1065.809
#411	SMAD5	6	21	27	2436.468
#412	CREBZF	6	16	22	478.914
#413	ARNT2	6	27	33	2327.469
#414	LZTR1	6	14	20	387.516
#415	FOXF1	6	15	21	209.771
#416	EGR1	5	15	20	246.772
#417	ESRRG	5	17	22	1367.943
#418	TEAD2	5	23	28	2098.695
#419	MSRB2	5	19	24	445.174
#420	HOXA3	5	14	19	243.996
#421	IRX1	5	19	24	1126.898
#422	ZNF207	5	13	18	679.111
#423	HMBOX1	5	17	22	235.96
#424	KDM5A	5	14	19	90.745
#425	FOXQ1	5	28	33	742.153
#426	RCAN1	5	23	28	756.723
#427	HEY2	5	18	23	731.536
#428	RARA	5	25	30	461.486
#429	IRX4	5	13	18	440.577
#430	ARNTL	5	16	21	1536.858
#431	NKX3-1	5	24	29	1044.276
#432	TCF3	5	21	26	703.389
#433	TSC22D2	5	17	22	833.226
#434	ETV4	5	21	26	934.39
#435	NFKB1	5	14	19	861.695
#436	MMP14	5	23	28	408.169
#437	MAFF	5	23	28	481.637
#438	HNF4G	5	23	28	771.207
#439	ELF5	4	30	34	1265.099
#440	IRF9	4	13	17	410.178
#441	SMAD9	4	37	41	490.988
#442	TFCP2L1	4	21	25	410.696
#443	ELF3	4	21	25	347.617
#444	RARB	4	28	32	788.101
#445	SOX11	4	24	28	1345.069
#446	HOXA2	4	15	19	182.273
#447	ATF5	4	20	24	306.838
#448	SREBF1	4	17	21	276.101
#449	HOXB7	4	19	23	204.271
#450	ZNF33B	4	17	21	874.683
#451	ZXDC	4	21	25	365.509
#452	TSC22D1	4	23	27	456.133
#453	TRERF1	4	19	23	298.433
#454	GATAD1	4	22	26	479.171
#455	FOXL1	4	11	15	339.316
#456	TP53	4	23	27	786.908
#457	SOX9	4	33	37	2361.787
#458	SATB2	4	18	22	1602.869
#459	TWIST2	4	21	25	368.007
#460	GATA2	4	22	26	2499.451
#461	TSHZ1	4	19	23	358.511
#462	FOXL2	4	18	22	217.085
#463	ISL1	3	10	13	338.384
#464	HOXB2	3	15	18	1522.312
#465	FOXC1	3	21	24	1597.631
#466	SCML1	3	26	29	670.131
#467	ZNF281	3	25	28	234.519
#468	HOXA10	3	29	32	343.175
#469	LHX9	3	14	17	320.141
#470	ZNF85	3	21	24	1591.938
#471	DLX4	3	22	25	950.294
#472	TBX3	3	26	29	2288.663
#473	ETS2	3	26	29	307.129
#474	NR1D2	3	23	26	92.214
#475	CDKN2A	3	23	26	494.262
#476	NFE2L3	3	22	25	695.587
#477	WT1	3	21	24	262.753
#478	PLAG1	3	17	20	115.031
#479	ZNF165	2	23	25	348.614
#480	SCAND3	2	24	26	627.679
#481	IRF5	2	29	31	354.166
#482	SOX8	2	17	19	272.789
#483	HOXA7	2	22	24	143.03
#484	TSHZ2	2	19	21	461.317
#485	PAX7	2	17	19	346.347
#486	TCFL5	2	20	22	391.821
#487	CREB5	2	27	29	1152.97
#488	ASCL1	2	15	17	316.471
#489	ZHX1	2	23	25	569.462
#490	CTBP1	2	26	28	991.921
#491	ZNF268	2	19	21	424.142
#492	DBP	1	20	21	124.15
#493	THRB	1	20	21	128.07
#494	HOXC10	1	30	31	71.79
#495	TGIF1	1	21	22	503.121
#496	NPAS2	1	18	19	495.41
#497	HOXD4	1	24	25	308.964
#498	PHTF1	1	19	20	67.293
#499	MEOX1	0	18	18	0
#500	PPARA	0	28	28	0