Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	PAX3	62	3	65	376.012
#2	KLF5	59	7	66	451.117
#3	SOX9	59	12	71	643.43
#4	SOX10	59	2	61	60.692
#5	ZNF165	57	5	62	5053.372
#6	MITF	56	7	63	1010.796
#7	NR3C1	49	2	51	257.142
#8	ETV5	49	6	55	1787.993
#9	IRF6	49	2	51	45.42
#10	CDX2	49	4	53	530.898
#11	ALX1	48	6	54	361.421
#12	FOXQ1	46	7	53	408.842
#13	ELF3	45	4	49	302.058
#14	LZTS1	45	5	50	255.366
#15	HES6	44	8	52	1472.196
#16	EHF	43	8	51	137.135
#17	MTA2	42	11	53	1941.567
#18	GAS7	41	7	48	265.015
#19	IRF1	41	11	52	490.014
#20	ZEB2	40	4	44	562.214
#21	TBX2	39	9	48	256.414
#22	HNF4A	38	10	48	669.078
#23	SNAI2	38	12	50	1888.232
#24	LASS6	38	9	47	3978.28
#25	OVOL1	37	10	47	803.845
#26	TWIST2	37	11	48	8176.973
#27	FOSL1	36	9	45	1248.061
#28	MYCL1	36	12	48	2466.121
#29	PITX1	35	6	41	114.35
#30	IRX4	35	10	45	2632.003
#31	DLX1	35	10	45	183.235
#32	SOX5	34	11	45	1891.254
#33	PPARG	34	10	44	1292.865
#34	GRHL2	34	3	37	62.752
#35	ETS2	33	13	46	646.902
#36	SIX1	33	7	40	663.837
#37	NR4A3	32	7	39	1057.875
#38	TCF7	32	8	40	1229.899
#39	HMGA1	32	9	41	1095.67
#40	MEIS1	30	11	41	1240.544
#41	ASCL2	30	6	36	536.005
#42	TRIM29	30	5	35	485.005
#43	HOXC4	30	6	36	141.119
#44	MNX1	29	14	43	1702.365
#45	HOXD13	29	15	44	2965.547
#46	KLF4	29	19	48	687.031
#47	EPAS1	29	13	42	890.89
#48	ZEB1	29	13	42	5608.546
#49	ELK3	29	9	38	2596.159
#50	TWIST1	29	12	41	1954.355
#51	HNF4G	29	14	43	1113.193
#52	HOXC9	29	9	38	398.567
#53	C11orf9	29	13	42	753.104
#54	KLF15	29	11	40	758.068
#55	CREM	29	9	38	2902.345
#56	TFAP2A	28	20	48	5721.222
#57	ZFP36L2	28	9	37	1353.767
#58	SALL2	28	15	43	1015.597
#59	MAFF	28	16	44	3379.688
#60	TRERF1	28	16	44	3635.696
#61	STAT6	27	9	36	2940.618
#62	ZSCAN18	27	8	35	966.357
#63	ZNF274	27	9	36	4204.586
#64	GATA6	27	11	38	1647.024
#65	FOXA1	26	13	39	735.504
#66	MECOM	26	18	44	1899.549
#67	DLX2	26	7	33	467.248
#68	FOXD3	26	10	36	264.839
#69	AEBP1	25	9	34	1499.064
#70	NR4A1	25	12	37	1139.296
#71	BCL3	25	8	33	499.563
#72	FOXL1	24	14	38	1120.571
#73	SOX13	24	14	38	1352.537
#74	CITED2	24	15	39	1587.559
#75	LEF1	24	10	34	672.675
#76	MLXIPL	24	11	35	705.558
#77	HNF1B	24	14	38	723.426
#78	HOXA13	24	9	33	1031.585
#79	CITED1	23	12	35	372.022
#80	FOXE1	23	11	34	1352.896
#81	RUNX3	23	19	42	4443.109
#82	POU3F1	23	12	35	279.857
#83	SMAD3	22	14	36	670.258
#84	POU3F3	22	11	33	1091.461
#85	ETV6	22	12	34	1442.417
#86	HOXA9	22	10	32	442.385
#87	RXRG	22	9	31	682.828
#88	TCF12	22	15	37	1688.926
#89	BATF3	22	9	31	680.962
#90	TBX3	22	17	39	2034.853
#91	HOXC13	22	9	31	575.769
#92	NR1H3	22	9	31	471.478
#93	FOXA3	22	9	31	234.549
#94	PROX1	21	13	34	815.827
#95	ZIC1	21	16	37	747.069
#96	ARNTL2	21	11	32	820.232
#97	AHR	21	19	40	4864.177
#98	RFXAP	21	10	31	2016.958
#99	HDX	20	14	34	831.066
#100	ETS1	20	10	30	673.58
#101	PKNOX2	20	7	27	73.411
#102	MSX2	20	15	35	2367.845
#103	NR4A2	20	10	30	1134.649
#104	SPDEF	20	13	33	1468.098
#105	MXD1	20	13	33	374.096
#106	SOX18	20	17	37	3526.743
#107	FOSL2	20	18	38	1645.958
#108	TFCP2L1	20	15	35	1859.004
#109	SATB2	20	15	35	5084.378
#110	FOXP4	20	11	31	1080.209
#111	EGR3	20	16	36	1084.484
#112	CTNNB1	20	7	27	177.526
#113	NFKB2	20	13	33	2887.526
#114	NKX6-2	20	17	37	1931.254
#115	SIM2	20	14	34	1271.269
#116	SOX6	19	5	24	455.409
#117	ETV4	19	17	36	2533.814
#118	SOX7	19	14	33	946.097
#119	ZNF287	19	18	37	2455.79
#120	IRX3	19	17	36	1228.906
#121	TCF7L1	19	16	35	1090.453
#122	CSRNP3	19	16	35	2165.376
#123	EN2	19	9	28	844.148
#124	RCAN1	19	16	35	888.26
#125	CEBPA	19	8	27	235.452
#126	NFIX	19	13	32	1711.485
#127	MAF	19	14	33	1355.729
#128	SCML1	19	15	34	2404.018
#129	HOXB9	18	7	25	157.411
#130	STRN3	18	10	28	1047.479
#131	RBCK1	18	12	30	683.344
#132	PBX1	18	16	34	1447.993
#133	HOXA7	18	8	26	376.48
#134	CREB3L1	18	13	31	1765.101
#135	HOXB3	18	7	25	380.1
#136	HOXD4	18	8	26	762.096
#137	C1orf85	18	12	30	1309.409
#138	TSC22D1	17	9	26	2160.378
#139	POU6F1	17	15	32	375.991
#140	WNT5A	17	14	31	1769.608
#141	KLF7	17	14	31	1336.318
#142	BCL11B	17	15	32	447.205
#143	ZNF134	17	7	24	128.383
#144	MYC	17	11	28	1703.788
#145	EBF1	17	18	35	577.876
#146	HES1	17	14	31	1293.359
#147	HOXB5	17	4	21	362.756
#148	HOXC10	17	5	22	950.5
#149	BARX1	17	14	31	1215.444
#150	ZHX2	17	15	32	1791.082
#151	NR1I2	16	11	27	425.211
#152	ZFPM2	16	10	26	1258.13
#153	ZNF643	16	14	30	1793.046
#154	HEY1	16	13	29	692.146
#155	HMX2	16	7	23	509.691
#156	ZNF238	16	18	34	1616.801
#157	NR2F1	16	15	31	2114.844
#158	POU3F2	16	7	23	101.805
#159	HOXB6	16	10	26	554.145
#160	POU2F2	16	10	26	1001.141
#161	NR2F6	16	10	26	1618.143
#162	HOXB8	15	12	27	614.801
#163	JUN	15	13	28	2190.944
#164	GLIS2	15	13	28	3010.947
#165	FOXN3	15	18	33	3221.096
#166	HOXA4	15	14	29	1253.19
#167	FOXO6	15	15	30	2199.743
#168	HOXA1	15	9	24	759.974
#169	ZNF91	15	14	29	1357.643
#170	GBX2	15	14	29	1675.826
#171	SMAD1	15	13	28	1327.872
#172	GLI3	15	15	30	1031.201
#173	FOXF1	15	14	29	3254.629
#174	ZNF33B	15	12	27	402.777
#175	IRF8	15	11	26	1158.04
#176	FOXD1	15	22	37	3233.639
#177	BTG2	15	16	31	900.598
#178	CREB3L2	15	14	29	1143.475
#179	USF1	15	6	21	1591.055
#180	FOXP1	14	19	33	1259.506
#181	POU2F3	14	13	27	638.018
#182	NEUROD1	14	7	21	753.644
#183	RORC	14	15	29	1440.647
#184	MEIS3P1	14	13	27	1054.885
#185	TCF4	14	17	31	2773.463
#186	FLI1	14	13	27	1126.941
#187	NR0B1	14	13	27	1323.533
#188	HOXA11	14	5	19	259.24
#189	SLC26A3	14	12	26	617.66
#190	ZXDC	14	10	24	582.941
#191	NR2F2	14	20	34	790.823
#192	HCLS1	14	12	26	1836.521
#193	NKX2-1	14	18	32	2117.148
#194	SMAD9	14	15	29	1041.228
#195	SMAD6	14	17	31	1021.005
#196	MMP14	14	12	26	469.56
#197	TSHZ3	14	14	28	1348.78
#198	PLAG1	14	19	33	1877.904
#199	TRPS1	14	21	35	1194.702
#200	KLF9	14	14	28	812.426
#201	SOX15	14	10	24	1293.906
#202	NFE2L3	13	16	29	1374.622
#203	NR2E1	13	9	22	483.284
#204	JDP2	13	15	28	559.115
#205	ZNF219	13	19	32	1842.695
#206	IRF9	13	14	27	919.91
#207	SIX4	13	18	31	2574.198
#208	SALL1	13	21	34	2516.221
#209	HOXA10	13	14	27	1720.751
#210	ISX	13	14	27	364.515
#211	OLIG2	13	13	26	1118.984
#212	GRHL3	13	15	28	1291.203
#213	CREB3L3	13	14	27	780.274
#214	FOXA2	13	19	32	673.639
#215	PRRX1	13	13	26	819.145
#216	GLIS3	13	21	34	1833.119
#217	ZNF277	13	10	23	707.66
#218	POU5F1B	13	13	26	853.087
#219	HOXB7	12	20	32	1519.212
#220	KCNH8	12	11	23	768.751
#221	CSDA	12	10	22	935.684
#222	PITX2	12	13	25	407.577
#223	FOXG1	12	17	29	1878.128
#224	SCAND2	12	18	30	3208.8
#225	FUBP1	12	17	29	1470.299
#226	PRDM1	12	14	26	506.227
#227	TSHZ1	12	19	31	1800.157
#228	NPAS1	12	14	26	500.488
#229	NFIB	12	21	33	1750.437
#230	LHX8	12	19	31	1227.196
#231	MSX1	12	18	30	988.566
#232	IRX5	12	19	31	1400.879
#233	FOXF2	12	14	26	2089.379
#234	NKX2-8	12	10	22	684.933
#235	LHX2	12	20	32	1166.906
#236	TAF4	12	16	28	1629.166
#237	ZNF131	12	18	30	864.383
#238	LHX1	12	14	26	933.421
#239	PGBD1	11	15	26	810.734
#240	GATA2	11	18	29	1336.684
#241	VDR	11	11	22	492.001
#242	IRF7	11	16	27	1096.179
#243	VAV1	11	20	31	1493.376
#244	SOX11	11	17	28	1770.757
#245	ATOH1	11	15	26	2518.075
#246	NFIA	11	16	27	1321.854
#247	IRF5	11	18	29	1277.627
#248	HMG20B	11	13	24	881.228
#249	MYT1	11	14	25	1027.581
#250	SMAD4	11	19	30	1567.947
#251	ZNF167	11	23	34	1914.149
#252	HOXA3	11	24	35	1733.186
#253	ALS2CR8	11	12	23	535.769
#254	RERE	11	14	25	916.295
#255	PEG3	11	12	23	674.328
#256	HIF3A	11	16	27	1523.869
#257	ZFHX4	11	11	22	365.388
#258	TEAD2	11	18	29	1154.87
#259	RARA	11	13	24	1234.683
#260	HEY2	11	19	30	686.036
#261	NFE2	11	14	25	1073.23
#262	ZNF396	11	12	23	623.875
#263	BATF2	11	10	21	333.463
#264	ELF4	11	17	28	563.422
#265	MESP1	11	17	28	987.212
#266	MSC	11	17	28	866.032
#267	TFAP2C	11	23	34	1644.462
#268	SOX8	10	15	25	310.994
#269	POU4F1	10	20	30	546.166
#270	ENO1	10	14	24	786.171
#271	ASCL1	10	14	24	1426.39
#272	ZFP37	10	23	33	2786.272
#273	ESR1	10	16	26	1121.089
#274	MYCN	10	18	28	1371.236
#275	HOPX	10	18	28	1179.762
#276	HOXA2	10	16	26	1563.555
#277	ESRRG	10	14	24	726.245
#278	ZNF135	10	10	20	447.284
#279	PLSCR1	10	14	24	843.395
#280	ZSCAN20	10	13	23	624.441
#281	THRB	10	16	26	1496.633
#282	VTN	10	18	28	2555.994
#283	TP53	10	20	30	1761.782
#284	NKX2-5	10	20	30	1042.227
#285	SIX2	10	18	28	738.652
#286	HOXD10	10	9	19	1629.877
#287	TP73	10	20	30	1700.552
#288	ZNF85	10	19	29	1798.684
#289	NOTCH1	10	19	29	1360.159
#290	PRRX2	10	15	25	1032.938
#291	IRF4	10	14	24	1090.185
#292	DLX6	10	16	26	877.856
#293	HR	10	10	20	497.627
#294	ERG	10	13	23	1152.376
#295	EGR2	9	14	23	577.476
#296	GATA4	9	22	31	1000.432
#297	RORB	9	16	25	984.599
#298	ST18	9	12	21	533.299
#299	FOXK1	9	15	24	2048.377
#300	ZNF117	9	15	24	1993.226
#301	MYOD1	9	5	14	376.149
#302	FOSB	9	15	24	1457.317
#303	ONECUT2	9	16	25	1490.086
#304	ZNF444	9	16	25	1002.291
#305	NFYC	9	16	25	1250.108
#306	ZHX3	9	19	28	1792.074
#307	C12orf28	9	7	16	546.326
#308	ZNF256	9	11	20	197.184
#309	KDM5A	9	15	24	1253.313
#310	ATF3	9	14	23	356.895
#311	ATF2	9	14	23	710.599
#312	TP63	9	17	26	1059.912
#313	ETV1	9	13	22	228.167
#314	HOXB2	9	18	27	1777.464
#315	ZNF132	9	19	28	2459.014
#316	ZNF323	9	14	23	895.28
#317	BCL6	9	18	27	759.165
#318	EN1	9	19	28	1506.666
#319	ZIC5	9	13	22	479.65
#320	RB1	9	14	23	2803.385
#321	SCAND3	8	15	23	485.439
#322	POU1F1	8	17	25	980.612
#323	PBX3	8	13	21	360.523
#324	MEOX1	8	15	23	713.774
#325	NFATC1	8	13	21	731.495
#326	MEF2C	8	14	22	857.096
#327	NR3C2	8	16	24	1741.488
#328	CREB5	8	17	25	516.075
#329	ZIC3	8	12	20	1087.988
#330	ZNF268	8	11	19	1004.164
#331	SATB1	8	13	21	524.214
#332	NFATC2	8	15	23	1161.251
#333	NCOR1	8	14	22	1088.131
#334	RARB	8	14	22	2854.368
#335	RUNX1	8	16	24	625.358
#336	ARNT2	8	21	29	664.352
#337	LMO4	8	16	24	1480.845
#338	SNAPC4	8	13	21	621.78
#339	EGR1	8	15	23	510.641
#340	SIX3	8	21	29	647.384
#341	ZFHX3	8	11	19	392.076
#342	HNRNPAB	8	14	22	859.798
#343	RUNX2	8	20	28	1464.521
#344	ZNF446	8	15	23	402.414
#345	GCM1	8	11	19	744.532
#346	IRX1	8	19	27	1911.684
#347	MYF5	8	16	24	1164.297
#348	NKX3-1	8	14	22	541.867
#349	ZNF71	8	16	24	1329.441
#350	ZNF140	8	13	21	777.849
#351	SOX2	8	23	31	2763.344
#352	HOXB13	8	20	28	427.055
#353	GATAD2B	8	18	26	1394.165
#354	BHLHE41	8	18	26	979.221
#355	FOXC1	8	13	21	744.18
#356	GLI2	7	21	28	1588.592
#357	ZIC2	7	22	29	1110.74
#358	TRIM22	7	17	24	933.512
#359	SMAD2	7	14	21	921.098
#360	RUNX1T1	7	13	20	651.899
#361	NFATC4	7	14	21	1537.774
#362	GATA5	7	15	22	1199.428
#363	TFAP2B	7	7	14	181.724
#364	SOX1	7	16	23	586.24
#365	PBX4	7	16	23	831.747
#366	SOX30	7	13	20	278.16
#367	MBD1	7	16	23	413.989
#368	MEIS2	7	15	22	762.181
#369	BNC1	7	16	23	568.629
#370	DLX3	7	16	23	778.999
#371	NR1H4	7	18	25	1413.185
#372	FOXJ1	7	14	21	703.859
#373	HOXC5	7	15	22	383.652
#374	ZNF397	7	18	25	978.654
#375	MSRB2	7	14	21	777.749
#376	EMX1	7	14	21	421.542
#377	ZSCAN4	7	16	23	923.116
#378	ZSCAN23	7	13	20	783.336
#379	TCF7L2	7	16	23	754.039
#380	TBX5	7	10	17	734.197
#381	ATF6B	7	12	19	384.611
#382	ZNF175	7	22	29	1660.608
#383	TADA3	7	18	25	1188.838
#384	NANOG	7	16	23	790.33
#385	T	7	13	20	965.677
#386	CREBZF	7	19	26	1188.253
#387	DMRT1	7	17	24	803.15
#388	AFF4	7	19	26	916.452
#389	THRA	7	11	18	690.417
#390	ZNF3	7	14	21	1645.386
#391	CEBPD	6	15	21	428.053
#392	HOXD3	6	13	19	113.76
#393	LHX9	6	18	24	865.628
#394	HLF	6	18	24	1927.38
#395	HHEX	6	21	27	1658.568
#396	MLLT10	6	16	22	571.225
#397	ISL1	6	16	22	756.59
#398	ETV7	6	17	23	766.426
#399	BATF	6	16	22	1305.389
#400	TFDP2	6	16	22	1011.597
#401	FOS	6	15	21	508.405
#402	TBX1	6	19	25	497.101
#403	MEIS3	6	18	24	1013.857
#404	IKZF3	6	16	22	612.548
#405	GATAD2A	6	20	26	2787.302
#406	ELF5	6	16	22	770.737
#407	MYT1L	6	15	21	645.591
#408	PTH	6	14	20	786.011
#409	MAFB	6	18	24	493.244
#410	GATA3	6	19	25	280.414
#411	SOX4	6	21	27	1496.966
#412	PPARD	6	14	20	1663.108
#413	TSC22D3	6	20	26	810.238
#414	GSC2	6	15	21	1301.111
#415	VSX1	6	15	21	814.353
#416	ZNF157	6	17	23	1257.672
#417	HOXA5	6	16	22	1000.472
#418	KLF2	6	14	20	537.331
#419	ZNF154	6	17	23	1114.771
#420	NPAS2	6	24	30	1434.083
#421	NFYA	6	12	18	542.039
#422	PAX6	6	18	24	760.633
#423	ZNF83	6	22	28	815.459
#424	OTX2	6	16	22	1192.605
#425	RORA	6	23	29	569.471
#426	TFEB	5	15	20	354.232
#427	ZNF90	5	13	18	685.293
#428	WT1	5	27	32	839.461
#429	MKX	5	16	21	669.51
#430	SPIC	5	14	19	345.915
#431	ARNT	5	14	19	444.286
#432	MEOX2	5	17	22	659.364
#433	STAT2	5	16	21	428.924
#434	ZNF207	5	17	22	373.121
#435	TSHZ2	5	24	29	976.639
#436	HMGA2	5	21	26	956.151
#437	MLL	5	13	18	505.937
#438	FOXL2	5	21	26	882.083
#439	NRL	5	14	19	641.003
#440	ZNF93	5	13	18	820.616
#441	MTA3	5	14	19	646.795
#442	AR	5	21	26	586.329
#443	EGR4	5	23	28	767.222
#444	ZNF215	5	20	25	1795.437
#445	BLZF1	5	15	20	562.131
#446	HIC1	5	14	19	688.239
#447	FOXC2	4	20	24	2408.205
#448	FOXO1	4	17	21	262.572
#449	ZSCAN12	4	13	17	265.416
#450	MAFG	4	15	19	1033.337
#451	FOXO3	4	17	21	1033.242
#452	KLF12	4	13	17	366.84
#453	TFEC	4	16	20	521.485
#454	SNAPC5	4	13	17	278.888
#455	ZNF24	4	16	20	572.066
#456	SIM1	4	21	25	742.494
#457	ZNF496	4	18	22	664.45
#458	IRX2	4	24	28	544.394
#459	ESX1	4	13	17	176.549
#460	NKX2-3	4	24	28	633.652
#461	TFDP1	4	20	24	744.403
#462	HSF5	4	13	17	404.21
#463	TCF20	4	15	19	570.593
#464	PRDM2	4	16	20	411.952
#465	L3MBTL4	4	18	22	420.521
#466	PPARA	4	16	20	839.763
#467	SPIB	4	15	19	194.909
#468	TBX22	4	21	25	1081.623
#469	CTBP1	3	17	20	345.104
#470	STAT5B	3	15	18	372.043
#471	ZFP42	3	15	18	426.898
#472	CDKN2A	3	24	27	1101.315
#473	HOXD11	3	15	18	498.195
#474	ZNF80	3	17	20	472.264
#475	ZNF81	3	17	20	301.266
#476	BACH2	3	14	17	65.889
#477	ANKRD30A	3	16	19	363.294
#478	DMRT2	3	21	24	329.232
#479	ELK4	3	16	19	204.387
#480	TAF13	3	16	19	384.802
#481	FOXP2	3	17	20	3068.64
#482	TEF	3	18	21	399.131
#483	HESX1	3	20	23	503.113
#484	ISL2	3	22	25	809.339
#485	ARX	2	16	18	207.347
#486	IKZF1	2	14	16	248.328
#487	LHX6	2	22	24	234.913
#488	TLX3	2	16	18	1593.56
#489	MGA	2	20	22	320.975
#490	NPAT	2	17	19	266.26
#491	BHLHE40	2	15	17	172.168
#492	LMX1A	2	14	16	80.079
#493	KLF16	2	11	13	258.659
#494	TCF21	2	15	17	251.116
#495	NR5A2	1	30	31	604.59
#496	DMBX1	1	16	17	26.103
#497	PAX8	1	15	16	108.357
#498	POU6F2	1	17	18	62.733
#499	ZFP36L1	1	14	15	144.086
#500	TULP4	0	19	19	0