Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	IRF8	52	5	57	761.758
#2	USF2	47	2	49	119.6
#3	HDAC1	46	7	53	555.789
#4	TCF7L2	44	7	51	1749.714
#5	E2F4	43	1	44	170.483
#6	FOSB	42	5	47	148.295
#7	ZNF83	39	7	46	1545.047
#8	ZNF238	39	4	43	201.194
#9	HHEX	39	8	47	829.591
#10	FUBP1	38	2	40	210.035
#11	ATF3	38	5	43	773.354
#12	PCGF2	37	3	40	151.115
#13	TAF4	37	4	41	638.946
#14	MAFF	35	8	43	2081.507
#15	PRDM1	34	10	44	615.175
#16	EVX1	33	6	39	657.023
#17	ZNF45	33	7	40	1085.058
#18	NFATC1	33	11	44	744.039
#19	STAT6	33	3	36	123.719
#20	SPDEF	33	3	36	1039.755
#21	NFIL3	33	10	43	6121.915
#22	ADNP	32	4	36	361.244
#23	CREBBP	31	8	39	5675.365
#24	HSF4	31	8	39	848.441
#25	HR	31	9	40	2559.917
#26	FOS	31	8	39	4787.796
#27	HMX1	30	10	40	708.37
#28	NR2C1	30	6	36	2322.482
#29	CITED2	30	11	41	3437.089
#30	ESRRA	30	1	31	29.762
#31	TCF12	30	7	37	2530.467
#32	FOXN3	30	4	34	126.697
#33	UBP1	30	8	38	755.862
#34	ATF1	30	3	33	266.809
#35	ZBTB17	29	8	37	3618.833
#36	TCF7	29	9	38	2391.973
#37	RARG	29	6	35	694.994
#38	XBP1	28	11	39	917.211
#39	ETV4	28	7	35	3808.298
#40	NKX3-1	28	4	32	347.61
#41	RARA	28	9	37	1698.794
#42	GCFC1	28	4	32	570.018
#43	NPAS1	27	6	33	1664.53
#44	ZNF444	27	5	32	1887.389
#45	ZFP36L1	26	10	36	1511.339
#46	TCF15	26	8	34	447.862
#47	POU5F1B	26	7	33	552.996
#48	FOXO3	26	14	40	925.764
#49	HOXC8	26	5	31	4400.554
#50	DLX2	25	8	33	313.208
#51	ATF2	25	12	37	3482.135
#52	TRIM22	25	13	38	1027.454
#53	KDM5A	25	8	33	1150.232
#54	TCF3	25	11	36	840.873
#55	STAT5B	25	12	37	609.257
#56	RFX5	24	13	37	2516.668
#57	HNRNPAB	24	7	31	3186.939
#58	PAX8	24	9	33	605.061
#59	HNF1B	24	12	36	994.08
#60	ELK4	24	12	36	4390.037
#61	TFEB	23	16	39	7911.85
#62	GTF2H3	23	7	30	1556.065
#63	SOX13	23	11	34	915.798
#64	SOX10	23	5	28	2262.097
#65	ELK1	22	7	29	286.002
#66	HOXB1	22	10	32	11953.111
#67	SPIB	22	12	34	464.226
#68	MMP14	22	4	26	130.952
#69	TFAM	22	13	35	6619.607
#70	BACH2	22	11	33	781.136
#71	ZNF131	22	10	32	945.616
#72	ETV7	22	9	31	3007.778
#73	ZSCAN18	21	10	31	171.973
#74	ZNF274	21	9	30	734.948
#75	IRF2	21	6	27	847.475
#76	MEF2D	21	10	31	2721.21
#77	TSC22D4	21	6	27	1174.181
#78	REST	20	10	30	1359.862
#79	PITX3	20	10	30	2340.215
#80	HEYL	20	8	28	719.986
#81	GLI3	20	3	23	708.66
#82	SOX15	20	8	28	4155.648
#83	CTCF	20	13	33	1505.294
#84	ATF4	19	13	32	1488.983
#85	CREB3L1	19	9	28	915.101
#86	KLF5	19	6	25	1063.983
#87	CREBZF	19	13	32	2713.658
#88	MYT1	19	8	27	3814.174
#89	SNAPC2	19	5	24	383.637
#90	ZNF217	18	12	30	1933.708
#91	TARDBP	18	9	27	1165.974
#92	GABPB1	18	11	29	2762.321
#93	ZNF219	18	7	25	1359.372
#94	DRAP1	18	10	28	2650.106
#95	ZNF215	18	10	28	249.224
#96	ZKSCAN3	18	6	24	309.36
#97	NR1I2	18	7	25	6107.938
#98	BARX1	18	12	30	1455.369
#99	FOSL2	18	5	23	1926.204
#100	TBP	18	10	28	392.205
#101	ZNF167	17	10	27	1237.398
#102	JUN	17	8	25	1195.101
#103	CTBP1	17	15	32	2189.574
#104	FBXW7	17	11	28	1939.682
#105	MAX	17	9	26	746.022
#106	ZEB1	17	15	32	2066.475
#107	HMGB1	17	12	29	2689.293
#108	PRRX2	17	15	32	799.867
#109	NFYC	17	8	25	834.562
#110	GBX2	17	8	25	833.957
#111	SIX5	17	5	22	508.948
#112	ZNF174	17	11	28	799.689
#113	HOXC11	17	12	29	929.979
#114	CREB3L2	16	13	29	355.818
#115	NPAT	16	9	25	4006.427
#116	SIM2	16	9	25	4159.508
#117	NR1H2	16	12	28	1630.894
#118	HIF3A	16	9	25	659.974
#119	ELF3	16	11	27	4618.273
#120	SUPT4H1	16	13	29	6406.716
#121	VDR	16	15	31	626.163
#122	PRRX1	16	11	27	2476.871
#123	MYOG	16	10	26	294.642
#124	HOXA6	16	8	24	1743.18
#125	DDIT3	16	14	30	2873.581
#126	GAS7	16	11	27	2839.503
#127	FOXP3	15	7	22	1205.608
#128	NFYB	15	13	28	1300.404
#129	FOXO1	15	14	29	4080.629
#130	VSX1	15	8	23	512.721
#131	ZNF165	15	13	28	3719.477
#132	TRIM25	15	11	26	2988.241
#133	MSC	15	11	26	662.757
#134	FOXO4	15	4	19	171.372
#135	ELF1	15	11	26	3020.7
#136	PBX3	15	15	30	987.791
#137	HNF1A	15	12	27	4172.16
#138	ESR1	15	13	28	2210.419
#139	PKNOX2	15	8	23	3529.738
#140	NR4A1	15	11	26	1209.517
#141	TEF	15	9	24	3383.91
#142	ZNF85	15	11	26	1190.208
#143	RORC	14	7	21	1109.464
#144	SCAND1	14	13	27	7646.572
#145	SPI1	14	14	28	2874.5
#146	BUD31	14	12	26	5369.968
#147	SALL2	14	8	22	258.826
#148	TFAP4	14	9	23	482.664
#149	GBX1	14	11	25	1212.772
#150	POU3F1	14	8	22	1511.02
#151	SOX2	14	9	23	905.675
#152	CBFA2T3	14	9	23	413.423
#153	CNOT8	14	8	22	1145.435
#154	KLF9	14	17	31	16591.64
#155	NEUROD2	14	9	23	636.522
#156	TBX2	14	13	27	2870.82
#157	NKX2-1	13	9	22	1037.24
#158	ARID4A	13	11	24	2719.918
#159	SP3	13	16	29	4167.564
#160	EPAS1	13	13	26	1280.349
#161	TBX10	13	14	27	728.238
#162	KLF10	13	16	29	1541.336
#163	STRN3	13	7	20	1147.718
#164	MLL	13	17	30	1654.191
#165	ETV5	13	8	21	1378.903
#166	ELK3	13	14	27	2454.083
#167	ZNF232	12	11	23	1090.201
#168	SP140	12	12	24	1243.569
#169	MYF6	12	9	21	7698.399
#170	HIC1	12	9	21	640.406
#171	ONECUT2	12	8	20	998.332
#172	FEV	12	9	21	610.269
#173	BHLHE41	12	15	27	603.077
#174	FOXA2	12	13	25	1255.121
#175	ETV2	12	12	24	2505.084
#176	MGA	12	7	19	2802.825
#177	BTAF1	12	18	30	3486.847
#178	HCFC1	12	10	22	2615.28
#179	ZNF24	12	9	21	4423.734
#180	TLX3	12	6	18	462.015
#181	KLF15	12	10	22	1483.177
#182	TCF4	12	14	26	1121.847
#183	SLC30A9	12	14	26	1494.98
#184	ZNF189	11	14	25	2213.508
#185	NR1D2	11	9	20	1073.517
#186	BCL3	11	10	21	2873.397
#187	MSRB2	11	16	27	1352.079
#188	NCOR1	11	10	21	1959.86
#189	SOX21	11	10	21	897.056
#190	CEBPE	11	15	26	4895.54
#191	HMG20B	11	15	26	1636.055
#192	SIX3	11	11	22	3326.594
#193	LASS2	11	13	24	1871.43
#194	E2F5	11	9	20	236.982
#195	IRF6	11	8	19	2543.41
#196	TEAD4	11	9	20	640.874
#197	JUNB	11	14	25	1191.61
#198	STAT3	11	15	26	4734.644
#199	PURA	11	18	29	1887.16
#200	MAFB	11	14	25	1285.97
#201	RFXANK	11	10	21	3748.84
#202	REL	10	15	25	3097.59
#203	CDX2	10	8	18	1803.626
#204	RUNX2	10	8	18	545.399
#205	SIX1	10	8	18	714.496
#206	CEBPB	10	15	25	1401.093
#207	TCF25	10	18	28	3671.251
#208	ZNF281	10	14	24	7335.293
#209	ELF4	10	15	25	5942.524
#210	ZNF446	10	10	20	800.104
#211	FOXN1	10	11	21	3243.715
#212	ALX4	10	10	20	2573.459
#213	SNAPC5	10	9	19	962.098
#214	MYOD1	10	9	19	579.253
#215	ZNF207	10	12	22	2936.494
#216	IRF4	10	9	19	1094.799
#217	HMG20A	10	14	24	2276.541
#218	CBFB	10	13	23	595.49
#219	NFKB2	10	11	21	1212.987
#220	MEIS2	10	11	21	2717.509
#221	TFDP3	10	12	22	2981.403
#222	LZTS1	10	17	27	2483.373
#223	RBPJ	10	11	21	1509.833
#224	FOXJ3	10	7	17	1985.868
#225	ZNF236	10	13	23	6580.437
#226	PA2G4	10	13	23	254.19
#227	SOX4	10	13	23	1176.305
#228	RBCK1	9	11	20	623.57
#229	ECSIT	9	11	20	1384.659
#230	GATA1	9	12	21	1039.064
#231	CREBL2	9	15	24	2148.657
#232	WNT5A	9	11	20	2398.135
#233	RELA	9	9	18	3148.803
#234	GATAD1	9	10	19	1063.868
#235	KLF12	9	9	18	9342.135
#236	ZNF75D	9	8	17	1238.984
#237	EDF1	9	11	20	3481.531
#238	ZNF202	9	15	24	1153.252
#239	STAT2	9	9	18	1557.45
#240	CSDA	9	21	30	8841.586
#241	MBD1	9	10	19	908.917
#242	NPAS2	9	14	23	1029.145
#243	SMAD1	9	9	18	3046.584
#244	EMX1	9	15	24	1665.839
#245	ZEB2	9	15	24	1968.457
#246	BRD8	9	12	21	1302.952
#247	KLF4	8	17	25	6391.073
#248	PDX1	8	7	15	550.841
#249	ENO1	8	11	19	2066.38
#250	CREB3	8	11	19	1030.599
#251	MYC	8	15	23	1868.135
#252	PBX2	8	16	24	1043.423
#253	RAX	8	13	21	1159.393
#254	IRF1	8	20	28	3061.57
#255	ELF2	8	12	20	1318.882
#256	HEY1	8	12	20	6116.364
#257	NFIC	8	9	17	1718.328
#258	TAF5L	8	17	25	679.611
#259	ZNF93	8	12	20	1299.578
#260	TAF7	8	14	22	1297.56
#261	SMAD4	8	13	21	584.949
#262	HOXD10	8	10	18	1618.711
#263	FOXC1	8	15	23	1337.804
#264	BACH1	8	15	23	2350.94
#265	CUX1	8	16	24	1951.416
#266	TFCP2L1	8	9	17	1012.412
#267	HOXA9	8	3	11	366.016
#268	PRDM2	8	13	21	1044.584
#269	EGR4	8	13	21	573.54
#270	STAT5A	8	10	18	1436.458
#271	SMAD2	8	17	25	1045.988
#272	FLI1	8	19	27	2480.405
#273	LMO4	8	13	21	1507.736
#274	TGIF1	8	15	23	2945.473
#275	NR4A2	8	16	24	2354.728
#276	ZHX2	7	15	22	653.38
#277	TSC22D3	7	16	23	2401.9
#278	TCFL5	7	11	18	1587.529
#279	RUNX3	7	16	23	450.422
#280	YY1	7	11	18	1882.67
#281	ZNF148	7	12	19	353.155
#282	MZF1	7	19	26	3651.71
#283	CEBPD	7	9	16	1078.106
#284	HMGA1	7	18	25	1431.034
#285	MLXIPL	7	10	17	408.624
#286	TGIF2	7	13	20	710.939
#287	RUNX1	7	14	21	1673.547
#288	EGR1	7	13	20	1877.344
#289	ZNF500	7	9	16	858.963
#290	TP73	7	12	19	207.512
#291	TFE3	7	12	19	1341.732
#292	ZGPAT	7	8	15	635.442
#293	FOXG1	7	11	18	510.282
#294	HSF1	7	10	17	3878.524
#295	RUNX1T1	7	8	15	628.377
#296	LEF1	7	15	22	1188.418
#297	SNAPC4	7	8	15	9175.882
#298	RARB	7	8	15	622.127
#299	FOXL1	7	13	20	1119.441
#300	NANOG	7	15	22	1218.847
#301	SCAND2	7	12	19	1096.475
#302	FOXC2	7	11	18	658.436
#303	LHX5	7	10	17	3239.769
#304	TSC22D2	7	11	18	1783.255
#305	ESRRG	7	9	16	222.992
#306	CNOT7	6	12	18	627.46
#307	FOXK2	6	23	29	3427.454
#308	E4F1	6	6	12	621.298
#309	POU6F1	6	14	20	2695.776
#310	MXD1	6	8	14	783.735
#311	MSX2	6	10	16	185.307
#312	SMAD6	6	11	17	606.067
#313	MYBL2	6	11	17	439.016
#314	MTA1	6	14	20	572.998
#315	HCLS1	6	12	18	960.536
#316	IRF5	6	13	19	428.599
#317	TFDP1	6	10	16	2527.76
#318	NFX1	6	16	22	710.081
#319	CDKN2A	6	12	18	662.686
#320	CREB1	6	18	24	2432.503
#321	FOXM1	6	14	20	4096.42
#322	FOXJ1	6	10	16	871.168
#323	HMGB2	6	14	20	1538.651
#324	HDAC2	6	10	16	3115.463
#325	NFIX	6	7	13	112.917
#326	LHX3	6	11	17	705.074
#327	C2orf3	6	14	20	835.285
#328	FOXJ2	6	13	19	1724.156
#329	ZKSCAN1	6	14	20	813.736
#330	RCAN1	6	8	14	307.279
#331	ZNF277	6	15	21	2108.704
#332	ZFHX3	6	13	19	1759.161
#333	JUND	6	17	23	1388.435
#334	MSL3	6	8	14	205.04
#335	NFE2	6	8	14	1165.812
#336	KLF11	6	17	23	3606.125
#337	MTA2	6	13	19	816.932
#338	E2F1	6	11	17	1872.623
#339	HNRNPK	6	13	19	1693.366
#340	ZNF263	6	14	20	405.858
#341	RCOR1	6	15	21	666.705
#342	RORA	6	17	23	1342.846
#343	CNBP	6	12	18	921.184
#344	NFATC3	6	16	22	569.293
#345	STAT1	6	22	28	7589.059
#346	AATF	5	14	19	1648.665
#347	HOXC10	5	19	24	552.478
#348	ATF6	5	13	18	3951.989
#349	HOXA3	5	10	15	460.164
#350	PAX5	5	12	17	322.42
#351	HOXD3	5	12	17	612.436
#352	AFF1	5	13	18	845.208
#353	PBX1	5	15	20	2312.093
#354	MEF2C	5	17	22	2088.768
#355	SPEN	5	10	15	1901.388
#356	PPARD	5	13	18	488.646
#357	PKNOX1	5	13	18	298.352
#358	TAF5	5	15	20	522.379
#359	IRF3	5	19	24	2371.566
#360	MAFG	5	9	14	421.387
#361	TRIM28	5	16	21	1088.573
#362	C11orf9	5	13	18	305.242
#363	CLOCK	5	14	19	2706.774
#364	BCL6	5	19	24	5938.911
#365	NR2F6	5	10	15	331.775
#366	ETV1	5	7	12	366.733
#367	KLF1	5	15	20	3481.051
#368	NFATC4	5	12	17	489.942
#369	ZBTB48	5	12	17	1088.297
#370	ZNF133	5	8	13	917.233
#371	E2F3	5	15	20	1653.821
#372	SOLH	5	18	23	942.644
#373	NKX2-8	5	10	15	556.831
#374	BHLHE40	5	18	23	1661.969
#375	NR5A1	5	9	14	1055.113
#376	HINFP	5	11	16	249.645
#377	NR2F2	5	8	13	523.476
#378	DMTF1	5	18	23	2419.723
#379	TRPS1	4	10	14	229.545
#380	ZBTB38	4	13	17	1732.436
#381	RERE	4	9	13	131.689
#382	PLAG1	4	8	12	389.173
#383	ETS2	4	13	17	2566.701
#384	MEF2A	4	14	18	2629.282
#385	NFE2L1	4	13	17	2906.746
#386	CIR1	4	14	18	472.769
#387	MAF	4	4	8	605.614
#388	ZNF434	4	14	18	478.401
#389	KLF2	4	18	22	2645.381
#390	CTNNB1	4	16	20	376.056
#391	ZNF268	4	9	13	997.549
#392	SRF	4	9	13	845.06
#393	BCL11B	4	12	16	564.192
#394	ATF6B	4	11	15	1177.37
#395	IKZF1	4	14	18	576.36
#396	TFCP2	4	13	17	1211.363
#397	HOXB3	4	10	14	135.518
#398	HMBOX1	4	14	18	2078.596
#399	HOXA5	4	12	16	809.774
#400	TCEAL1	4	9	13	832.265
#401	HES1	4	11	15	1633.313
#402	RB1	4	14	18	300.362
#403	TBX5	4	9	13	721.305
#404	NFKB1	4	16	20	1929.395
#405	TAF12	4	11	15	1108.108
#406	TFEC	3	13	16	7029.496
#407	YBX1	3	17	20	1413.029
#408	LASS6	3	13	16	2351.491
#409	ZBTB25	3	14	17	498.761
#410	TSHZ2	3	11	14	900.035
#411	PHTF1	3	9	12	282.538
#412	CBFA2T2	3	12	15	178.829
#413	MYNN	3	17	20	669.85
#414	IRF9	3	14	17	256.75
#415	RXRB	3	13	16	291.489
#416	HIRA	3	11	14	1408.272
#417	POU2F1	3	13	16	731.204
#418	RNF4	3	8	11	93.146
#419	ZFP36L2	3	19	22	1065.1
#420	NR3C1	3	10	13	1001.981
#421	HOXC4	3	16	19	1052.454
#422	ZNF3	3	11	14	362.991
#423	STAT4	3	13	16	1512.636
#424	PLSCR1	3	10	13	493.789
#425	PTTG1	3	18	21	174.882
#426	SREBF2	3	14	17	1096.762
#427	TBX4	3	8	11	167.468
#428	MYCN	3	10	13	990.008
#429	SP4	3	10	13	368.829
#430	FOXB1	3	12	15	203.648
#431	PFDN1	3	11	14	549.153
#432	POU6F2	3	12	15	176.458
#433	SMAD3	3	12	15	498.814
#434	NOTCH1	3	11	14	1671.474
#435	TADA3	3	13	16	909.458
#436	RELB	3	9	12	205.187
#437	KDM5B	3	14	17	1472.991
#438	NR4A3	3	13	16	1728.334
#439	KLF6	3	15	18	336.771
#440	TP53	2	11	13	321.414
#441	NR6A1	2	15	17	103.873
#442	KLF7	2	16	18	4039.815
#443	T	2	10	12	649.167
#444	KLF3	2	11	13	140.553
#445	TAL1	2	10	12	1110.779
#446	UBN1	2	14	16	2042.916
#447	IKZF3	2	12	14	239.694
#448	BATF	2	13	15	175.493
#449	HOPX	2	6	8	552.53
#450	LHX1	2	12	14	171.852
#451	ZNF394	2	13	15	185.292
#452	OVOL1	2	13	15	1015.754
#453	NFAT5	2	10	12	525.322
#454	TAF10	2	11	13	356.178
#455	NR3C2	2	16	18	372.955
#456	MLX	2	17	19	1149.368
#457	NFIB	2	15	17	519.464
#458	CREM	2	10	12	1330.106
#459	TP63	2	12	14	140.61
#460	TSC22D1	2	13	15	1172.446
#461	BTG2	2	11	13	99.364
#462	HAND2	2	9	11	145.937
#463	ATOH1	2	16	18	2262.839
#464	SUPT6H	2	11	13	285.037
#465	HEY2	2	10	12	49.199
#466	NOLC1	2	14	16	273.325
#467	ZXDC	2	15	17	672
#468	ZNF91	2	13	15	529.181
#469	MNT	2	13	15	388.937
#470	HNF4A	2	15	17	536.194
#471	MITF	2	9	11	107.322
#472	ADNP2	2	9	11	743.565
#473	TFDP2	2	12	14	312.551
#474	GATA2	1	16	17	514.322
#475	HOXB2	1	12	13	178.697
#476	VAV1	1	14	15	630.91
#477	MTF1	1	11	12	33.402
#478	IRF7	1	15	16	66.314
#479	REXO4	1	14	15	1067.44
#480	PHF1	1	14	15	34.514
#481	TULP4	1	13	14	384.788
#482	ASCL1	1	14	15	318.555
#483	TCF20	1	13	14	152.112
#484	EGR3	1	8	9	32.125
#485	POU2F2	1	10	11	108.806
#486	PHOX2A	1	14	15	87.369
#487	EGR2	1	13	14	452.417
#488	SATB1	1	17	18	364.905
#489	ATF5	1	16	17	65.785
#490	RXRA	1	13	14	1322.184
#491	LZTR1	1	7	8	12.791
#492	ARNTL	1	12	13	177.993
#493	NFE2L2	1	13	14	1922.621
#494	ZSCAN16	0	12	12	0
#495	NKX6-1	0	15	15	0
#496	HIF1A	0	19	19	0
#497	TFAP2A	0	11	11	0
#498	DBP	0	8	8	0
#499	ESR2	0	7	7	0
#500	AEBP1	0	12	12	0