Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ERG	57	7	64	3768.434
#2	RUNX1T1	50	7	57	1302.797
#3	PHF1	50	5	55	1961.795
#4	FOXP4	47	8	55	651.695
#5	ELK4	43	8	51	2068.2
#6	HNRNPK	41	4	45	4514.676
#7	FOXO1	41	8	49	1614.674
#8	TSC22D2	40	6	46	2555.107
#9	FOSB	36	9	45	1470.95
#10	CREBBP	34	3	37	2363.447
#11	MYNN	32	7	39	947.735
#12	REL	32	4	36	781.705
#13	CSRNP1	31	5	36	832.675
#14	NFKB1	31	7	38	2019.335
#15	FOSL2	31	6	37	1293.89
#16	NR2F2	31	8	39	1283.834
#17	KLF9	31	7	38	1852.071
#18	SP3	30	5	35	294.529
#19	KLF6	30	7	37	441.04
#20	JUND	29	12	41	1364.103
#21	C5orf41	29	8	37	925.684
#22	ZXDC	29	7	36	6035.637
#23	ZNF165	29	6	35	593.578
#24	ZNF268	28	3	31	458.562
#25	RELA	27	10	37	3662.799
#26	IRF2	27	5	32	1462.609
#27	ZNF148	27	10	37	3489.525
#28	GATAD2B	26	11	37	4844.937
#29	ARNTL2	26	9	35	1822.511
#30	FOXJ2	25	10	35	4304.47
#31	E2F7	25	12	37	5856.515
#32	ZNF628	24	11	35	2864.169
#33	MEIS1	24	6	30	4273.412
#34	TEAD2	23	4	27	1163.817
#35	MAFF	23	9	32	473.335
#36	PRDM2	22	8	30	1286.538
#37	ZNF117	22	10	32	5518.336
#38	NR4A3	22	3	25	127.035
#39	ZNF498	22	10	32	3417.341
#40	HIF1A	21	10	31	846.796
#41	CREM	21	8	29	359.205
#42	MEF2D	21	4	25	541.81
#43	PKNOX2	21	8	29	1635.805
#44	RARB	21	15	36	1974.606
#45	FOXP1	21	8	29	2265.39
#46	STAT5A	21	13	34	3719.432
#47	RFX1	20	7	27	1733.7
#48	MEIS2	20	7	27	600.83
#49	SUPT6H	20	9	29	6320.045
#50	ZNF167	20	10	30	5082.757
#51	ATF2	19	4	23	956.762
#52	SNAI2	19	12	31	2217.246
#53	PBX1	19	12	31	2427.14
#54	TSC22D3	19	5	24	2469.627
#55	CNBP	19	5	24	786.099
#56	MLLT10	19	6	25	1229.357
#57	UBP1	19	7	26	2379.511
#58	ESR1	19	9	28	455.291
#59	GABPB1	18	8	26	734.015
#60	STAT4	18	8	26	1899.623
#61	RUNX3	18	9	27	4574.73
#62	TCF7L1	18	10	28	3965.378
#63	ZFPM2	18	6	24	878.964
#64	TCF20	18	4	22	345.122
#65	CCRN4L	18	10	28	493.008
#66	ELF2	17	9	26	1079.528
#67	NR1H2	17	10	27	941.552
#68	CBL	17	5	22	323.865
#69	KLF10	17	12	29	1597.855
#70	GCFC1	17	9	26	1740.496
#71	USF2	16	9	25	5109.388
#72	C2orf3	16	11	27	8293.021
#73	NFIB	16	6	22	291.506
#74	RELB	16	10	26	1349.999
#75	MTF1	16	6	22	1283.515
#76	JUN	16	6	22	179.428
#77	ZNF639	16	9	25	1836.356
#78	SCAND1	16	8	24	955.09
#79	TGIF1	16	6	22	514.465
#80	SP1	15	5	20	1819.933
#81	SMAD1	15	9	24	1502.704
#82	NFE2L1	15	10	25	1601.943
#83	MAX	15	14	29	1604.754
#84	CNOT8	15	6	21	1236.74
#85	MTA3	15	7	22	2207.849
#86	PAX8	15	5	20	438.067
#87	HEYL	14	15	29	7060.19
#88	SMAD3	14	13	27	4412.063
#89	WNT5A	14	12	26	4279.357
#90	MBD1	14	7	21	4735.722
#91	NR4A2	14	7	21	610.313
#92	NFE2L2	14	6	20	565.299
#93	NFATC1	14	8	22	1494.854
#94	ZNF175	14	8	22	678.902
#95	NR1H3	14	6	20	390.766
#96	TAF6	14	6	20	1742.047
#97	ETV5	14	8	22	581.471
#98	BCL11B	14	7	21	825.283
#99	BTG2	14	13	27	1152.017
#100	ZNF24	14	6	20	2769.155
#101	RXRA	13	8	21	1936.708
#102	ZNF33A	13	7	20	2805.893
#103	CITED2	13	7	20	553.185
#104	ZFPM1	13	13	26	2853.694
#105	NFIA	13	9	22	3926.194
#106	IRF3	13	5	18	494.595
#107	NCOR1	13	6	19	744.121
#108	LASS5	13	6	19	1437.333
#109	FOXG1	13	8	21	3155.824
#110	ZFP36L2	13	9	22	554.941
#111	ATF1	13	12	25	2718.653
#112	ATF4	13	10	23	1350.66
#113	TULP4	13	5	18	1830
#114	GABPA	13	10	23	1554.354
#115	ARID4A	13	12	25	8638.482
#116	AHCTF1	12	8	20	1415.242
#117	FOXK1	12	8	20	3640.134
#118	JUNB	12	4	16	806.858
#119	TADA3	12	4	16	1557.971
#120	FOS	12	6	18	1336.47
#121	NFYB	12	11	23	780.468
#122	GATAD1	12	10	22	2138.637
#123	HES6	12	9	21	536.886
#124	ZNF140	12	11	23	2496.805
#125	KDM5A	12	7	19	1188.052
#126	HMG20A	12	14	26	2483.187
#127	LHX6	12	8	20	1304.807
#128	SMAD9	12	10	22	2600.986
#129	TEAD1	12	10	22	2529.58
#130	FOXM1	12	5	17	286.137
#131	PURB	12	8	20	1209.387
#132	JDP2	12	14	26	1411.147
#133	E2F6	12	13	25	3080.785
#134	MSC	12	15	27	2478.218
#135	ETV3	12	9	21	1212.55
#136	ZEB1	12	10	22	955.06
#137	ZNF189	12	8	20	511.906
#138	MNT	11	8	19	1293.636
#139	TBX21	11	11	22	729.991
#140	E2F4	11	3	14	164.969
#141	STAT6	11	12	23	3196.482
#142	TAF4	11	8	19	1404.795
#143	NR1D2	11	10	21	524.104
#144	SOX7	11	10	21	3945.986
#145	CBFB	11	8	19	1909.347
#146	SPI1	11	9	20	1017.628
#147	ZNF238	11	11	22	1511.122
#148	ZNF274	11	9	20	5855.78
#149	POU3F1	11	11	22	1914.089
#150	ZNF232	11	9	20	3912.892
#151	TGIF2	11	9	20	1488.413
#152	HOXD4	11	9	20	2141.615
#153	SOX2	11	7	18	4277.89
#154	DRAP1	11	8	19	1527.877
#155	MAFB	11	10	21	754.24
#156	TAF7	11	9	20	758.885
#157	IRF9	11	7	18	730.254
#158	ENO1	11	12	23	2581.563
#159	SCML2	11	9	20	2312.147
#160	SREBF2	11	10	21	3032.97
#161	ZNF131	10	8	18	3488.188
#162	PRRX1	10	9	19	1583.019
#163	MAF	10	10	20	449.227
#164	TCF4	10	6	16	507.369
#165	KLF2	10	8	18	306.484
#166	BCL6	10	7	17	263.01
#167	PBX4	10	11	21	3925.536
#168	ZFP36L1	10	12	22	863.543
#169	ZNF394	10	10	20	1067.675
#170	MSL3	10	16	26	1354.809
#171	RUNX1	10	10	20	1078.602
#172	BATF2	10	5	15	365.129
#173	MEOX2	10	11	21	1814.074
#174	CLOCK	10	10	20	803.647
#175	SIN3A	10	8	18	297.374
#176	TAF10	10	4	14	697.02
#177	FOXF1	10	15	25	5272.345
#178	POU2F1	10	9	19	782.509
#179	YY1	10	6	16	1082.922
#180	HIRA	10	10	20	1057.984
#181	ADNP	10	9	19	760.797
#182	TCF19	10	7	17	2889.909
#183	CBFA2T2	10	7	17	470.662
#184	ZNF217	10	9	19	2042.692
#185	NFYC	10	10	20	1839.556
#186	ZIC1	10	7	17	5432.043
#187	NR2F6	10	13	23	4059.588
#188	ERF	10	13	23	2638.731
#189	ZKSCAN4	10	13	23	1247.907
#190	GATA2	10	7	17	2623.07
#191	ZFHX3	9	14	23	1808.49
#192	NFXL1	9	11	20	1550.862
#193	KLF12	9	12	21	1559.899
#194	MSRB2	9	12	21	1337.014
#195	PTTG1	9	5	14	1395.777
#196	CEBPB	9	11	20	1918.542
#197	NR3C1	9	9	18	341.593
#198	SATB1	9	11	20	1385.449
#199	ATF3	9	9	18	409.702
#200	UHRF1	9	8	17	1375.434
#201	SUPT4H1	9	8	17	570.638
#202	FBXW7	9	12	21	523.43
#203	HSF2	9	11	20	1073.614
#204	NFKB2	9	10	19	497.303
#205	OVOL1	9	11	20	605.778
#206	SOX8	9	5	14	412.618
#207	ZSCAN18	9	9	18	1639.314
#208	NFIL3	9	13	22	990.7
#209	PBX2	9	12	21	3314.387
#210	MITF	9	5	14	192.014
#211	STAT5B	9	7	16	2004.1
#212	TRIM28	9	10	19	2071.9
#213	ATF7	8	11	19	571.693
#214	NFIX	8	9	17	1000.361
#215	ZHX1	8	8	16	574.871
#216	DMRT2	8	9	17	1877.452
#217	IKZF4	8	11	19	1863.441
#218	ZNF256	8	11	19	2842.991
#219	NFYA	8	10	18	1885.875
#220	HOXB7	8	13	21	2311.76
#221	ARNT2	8	8	16	2445.622
#222	MZF1	8	14	22	1851.886
#223	TFEC	8	4	12	126.558
#224	LZTR1	8	9	17	628.564
#225	PPARA	8	10	18	778.962
#226	HOXD8	8	12	20	2991.698
#227	BACH2	8	11	19	371.566
#228	SATB2	8	9	17	948.542
#229	CEBPD	8	10	18	1313.028
#230	LMX1A	8	6	14	2418.733
#231	NFATC2	8	11	19	722.819
#232	FOXK2	8	8	16	949.423
#233	DDIT3	8	9	17	1004.859
#234	ETS1	8	9	17	708.91
#235	MLL	8	11	19	1777.426
#236	EN1	8	10	18	829.32
#237	EDF1	8	5	13	363.861
#238	LMO4	8	9	17	775.439
#239	KLF7	8	7	15	428.541
#240	TAL1	8	10	18	1815.303
#241	EGR4	7	12	19	2653.498
#242	NR5A2	7	11	18	1859.123
#243	CUX1	7	8	15	917.905
#244	GLIS2	7	11	18	1405.11
#245	HCLS1	7	8	15	1135.737
#246	PCGF2	7	6	13	482.602
#247	NOLC1	7	11	18	1974.97
#248	SPEN	7	10	17	1336.253
#249	NANOGNB	7	8	15	1498.498
#250	GLI3	7	10	17	376.986
#251	LCOR	7	11	18	996.442
#252	IRF7	7	14	21	2034.066
#253	BUD31	7	11	18	1549.392
#254	AHR	7	7	14	878.559
#255	KLF5	7	11	18	351.34
#256	MAFG	7	10	17	1733.798
#257	SMAD2	7	8	15	1198.899
#258	MGA	7	9	16	1566.926
#259	TSC22D1	7	14	21	1813.033
#260	TP53	7	11	18	3476.405
#261	ZNF18	7	5	12	2838.934
#262	NR2F1	7	11	18	353.257
#263	ZSCAN16	7	6	13	1049.585
#264	CBFA2T3	7	9	16	1276.208
#265	CEBPA	7	13	20	1387.136
#266	KDM5B	7	9	16	1749.191
#267	ONECUT2	7	7	14	2420.164
#268	ELK1	7	4	11	1103.623
#269	HES1	7	9	16	1727.967
#270	POU6F1	6	8	14	603.795
#271	FOXJ3	6	7	13	568.763
#272	EPAS1	6	7	13	97.724
#273	HNF1B	6	10	16	1495.849
#274	LASS2	6	9	15	791.601
#275	SMAD6	6	9	15	361.673
#276	MEOX1	6	10	16	3753.453
#277	AFF4	6	7	13	1085.39
#278	BCL3	6	16	22	1393.671
#279	HMGA1	6	7	13	403.05
#280	MTA1	6	12	18	1009.406
#281	FOXP3	6	4	10	818.331
#282	FOXN3	6	13	19	6041.854
#283	YBX1	6	10	16	1111.819
#284	E2F2	6	8	14	1217.864
#285	MSX1	6	9	15	671.236
#286	SNAPC4	6	13	19	3991.227
#287	STAT3	6	12	18	820.666
#288	EGR3	6	12	18	1842.628
#289	ZEB2	6	11	17	796.82
#290	MYCN	6	6	12	1241.87
#291	NFATC3	6	13	19	1121.282
#292	GATAD2A	6	11	17	2728.362
#293	STRN3	6	13	19	1212.789
#294	HIC1	6	12	18	2010.933
#295	ZNF91	6	12	18	1598.32
#296	GTF2I	6	10	16	1189.555
#297	SOX6	6	12	18	1329.373
#298	AATF	6	10	16	494.221
#299	PA2G4	6	9	15	785.861
#300	PPARD	6	10	16	428.106
#301	FUBP1	6	10	16	483.692
#302	SPDEF	6	11	17	2071.537
#303	TBX3	6	10	16	2318.393
#304	SMAD4	6	10	16	1232.871
#305	FLI1	6	11	17	723.299
#306	HCFC1	6	6	12	703.102
#307	TAF5L	6	12	18	2738.604
#308	RORA	6	10	16	744.418
#309	PROX1	6	11	17	1028.721
#310	RERE	6	8	14	690.149
#311	PLAG1	6	8	14	1803.595
#312	HOXA6	6	13	19	1706.548
#313	RAX2	6	12	18	3356.871
#314	NKX3-1	6	13	19	1509.065
#315	RFXAP	6	7	13	938.023
#316	RORC	6	8	14	1822.366
#317	HMGB1	5	7	12	956.069
#318	ATF5	5	10	15	440.285
#319	TFCP2	5	9	14	507.378
#320	MEF2C	5	9	14	95.578
#321	STAT1	5	11	16	541.964
#322	TSHZ1	5	10	15	430.845
#323	BHLHE41	5	10	15	1140.554
#324	CTNNB1	5	11	16	555.158
#325	RCOR1	5	12	17	773.354
#326	HHEX	5	14	19	1301.299
#327	ZBTB25	5	9	14	376.494
#328	TCF7	5	9	14	485.612
#329	MYBL2	5	12	17	2125.261
#330	E2F1	5	11	16	6600.801
#331	GAS7	5	11	16	1416.271
#332	TCF12	5	7	12	415.571
#333	EGR1	5	10	15	435.487
#334	RFX5	5	11	16	1293.492
#335	EBF1	5	10	15	413.449
#336	NR3C2	5	11	16	2240.559
#337	STAT2	5	14	19	1985.64
#338	ZIC2	5	7	12	4069.651
#339	E2F8	5	11	16	863.892
#340	TCF25	5	8	13	758.358
#341	E2F3	5	14	19	1608.986
#342	SMAD5	5	13	18	1068.229
#343	RB1	5	13	18	897.328
#344	IRF6	5	10	15	4418.606
#345	ZNF444	5	10	15	790.257
#346	CREB1	5	7	12	471.559
#347	SCML1	5	12	17	685.094
#348	MLX	5	13	18	1035.915
#349	ZNF92	5	9	14	461.284
#350	ARNTL	5	9	14	644.132
#351	NFE2L3	5	12	17	744.159
#352	TSC22D4	5	6	11	157.929
#353	MEF2A	5	11	16	892.14
#354	HEY1	5	12	17	1301.465
#355	FOXP2	4	12	16	2758.437
#356	NPAS2	4	9	13	2717.909
#357	RCAN1	4	12	16	1210.428
#358	ZNF396	4	8	12	895.272
#359	XBP1	4	9	13	141.979
#360	FOXO3	4	10	14	980.449
#361	GTF2H2	4	12	16	349.319
#362	BATF3	4	14	18	981.551
#363	ZNF397	4	12	16	334.411
#364	IRF8	4	11	15	1373.143
#365	HOXA1	4	9	13	1405.675
#366	ZNF496	4	11	15	1161.486
#367	PLSCR1	4	10	14	1600.566
#368	TAF4B	4	10	14	622.486
#369	GATA1	4	9	13	3379.325
#370	TRIM22	4	12	16	2523.883
#371	ZNF138	4	6	10	492.572
#372	ZNF367	4	8	12	263.821
#373	ZNF236	4	11	15	931.547
#374	EHF	4	4	8	781.08
#375	TCF7L2	4	10	14	217.07
#376	TSHZ2	4	11	15	2146.062
#377	HSF1	4	14	18	3058.677
#378	GATA3	4	8	12	474.998
#379	TCFL5	4	11	15	1111.92
#380	MXD1	4	12	16	1617.336
#381	TAF12	4	14	18	1726.892
#382	ZNF445	4	12	16	1079.944
#383	MEIS3P1	4	8	12	717.162
#384	KLF16	4	11	15	2152.442
#385	CSRNP2	4	7	11	593.854
#386	HMG20B	4	11	15	1658.006
#387	BLZF1	4	9	13	1043.037
#388	KLF3	4	15	19	1381.451
#389	CIR1	4	11	15	212.968
#390	IRF1	4	9	13	521.885
#391	ETV1	4	9	13	924.38
#392	ZNF33B	4	9	13	1246.291
#393	TCEAL1	4	9	13	965.021
#394	ZNF277	4	11	15	719.161
#395	HNRNPAB	4	12	16	425.342
#396	TFDP2	4	11	15	713.95
#397	NFX1	4	8	12	814.098
#398	CREBZF	4	11	15	615.386
#399	ELK3	3	15	18	640.869
#400	KLF11	3	11	14	197.983
#401	NFAT5	3	7	10	376.237
#402	ZNF93	3	10	13	2588.815
#403	ADNP2	3	8	11	288.946
#404	PRDM1	3	14	17	1735.11
#405	UBN1	3	12	15	540.805
#406	ELF1	3	8	11	807.779
#407	ZKSCAN1	3	8	11	257.086
#408	ZNF281	3	14	17	299.256
#409	RXRB	3	8	11	459.225
#410	LASS6	3	9	12	803.084
#411	HSF5	3	7	10	2496.307
#412	CNOT7	3	6	9	500.075
#413	PKNOX1	3	9	12	375.932
#414	ZHX2	3	14	17	484.282
#415	ELF4	3	8	11	879.241
#416	E2F5	3	11	14	1236.679
#417	MYCL1	3	9	12	511.34
#418	RUNX2	3	10	13	806.193
#419	SP4	3	10	13	1389.909
#420	BHLHE40	3	10	13	910.646
#421	CTBP1	3	15	18	4104.077
#422	SOX4	3	6	9	656.607
#423	CREBL2	3	14	17	226.33
#424	C1orf85	3	13	16	461.384
#425	CDKN2A	3	6	9	284.433
#426	PBX3	3	13	16	1300.804
#427	ZNF207	3	11	14	308.084
#428	HOXB4	3	11	14	1231.368
#429	MAFK	3	10	13	1406.349
#430	SP140	3	7	10	213.985
#431	BATF	3	13	16	1165.429
#432	NPAT	3	12	15	518.592
#433	YEATS4	3	12	15	541.315
#434	SCAND2	3	9	12	1748.78
#435	NOTCH1	3	13	16	313.002
#436	KLF4	3	11	14	1138.291
#437	HOXA7	3	8	11	77.903
#438	ZNF135	3	10	13	2556.938
#439	ZNF83	3	8	11	105.33
#440	HOXB2	3	10	13	984.027
#441	TSHZ3	2	8	10	212.899
#442	CREB3L1	2	9	11	683.398
#443	POU2F2	2	11	13	352.986
#444	TFEB	2	12	14	621.853
#445	TFAP2A	2	13	15	1045.909
#446	ZBTB38	2	13	15	635.887
#447	SLC2A4RG	2	9	11	196.362
#448	ZNF438	2	10	12	842.216
#449	CSDA	2	13	15	305.788
#450	TFAM	2	10	12	211.983
#451	RARA	2	11	13	3675.112
#452	IRX3	2	8	10	551.077
#453	LEF1	2	10	12	450.489
#454	MMP14	2	6	8	186.442
#455	HLF	2	9	11	154.027
#456	HOXA2	2	12	14	288.145
#457	VDR	2	11	13	276.561
#458	HOXA10	2	10	12	1141.769
#459	NR4A1	2	12	14	193.121
#460	ZNF3	2	11	13	2585.796
#461	GTF2H3	2	8	10	621.669
#462	POU5F1B	2	8	10	528.416
#463	HAND1	2	6	8	173.975
#464	GATA6	2	13	15	203.257
#465	HMGB2	2	9	11	2029.794
#466	ATF6	2	13	15	2619.525
#467	SPIB	2	12	14	800.036
#468	ZFP90	1	10	11	137.407
#469	IKZF1	1	12	13	288.68
#470	GLIS3	1	11	12	1481.023
#471	HOPX	1	10	11	111.238
#472	RBPJ	1	10	11	244.587
#473	PFDN1	1	7	8	220.271
#474	IRF4	1	18	19	252.243
#475	ETV7	1	14	15	440.169
#476	SREBF1	1	8	9	275.734
#477	NFIC	1	8	9	105.492
#478	TRPS1	1	6	7	50.974
#479	TP63	1	13	14	878.397
#480	BACH1	1	6	7	138.083
#481	TCF3	1	14	15	2366.071
#482	ZNF193	1	10	11	255.348
#483	ASCL2	1	15	16	1504.892
#484	TWIST1	1	16	17	326.427
#485	IRF5	1	10	11	167.875
#486	AEBP1	1	17	18	118.546
#487	ETV6	1	10	11	640.513
#488	MYC	1	8	9	348.659
#489	PHF5A	1	10	11	84.357
#490	ZNF85	1	8	9	118.009
#491	EOMES	1	11	12	642.242
#492	TRERF1	0	13	13	0
#493	HOXB3	0	13	13	0
#494	TFDP1	0	12	12	0
#495	CREB3L2	0	11	11	0
#496	HMBOX1	0	8	8	0
#497	ASCL1	0	8	8	0
#498	ETS2	0	13	13	0
#499	EGR2	0	12	12	0
#500	HOXA9	0	9	9	0