Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TULP4	42	2	44	184.343
#2	PEG3	38	2	40	261.994
#3	TCF3	36	1	37	415.905
#4	THRA	33	4	37	392.335
#5	CEBPB	32	3	35	746.701
#6	TGIF1	31	8	39	2977.339
#7	YBX1	30	11	41	2718.747
#8	SOX4	30	3	33	1281.397
#9	OLIG2	30	5	35	644.841
#10	FOXM1	30	3	33	1451.26
#11	ASCL1	29	6	35	769.779
#12	MEF2C	28	2	30	4875.443
#13	SATB1	28	8	36	4873.463
#14	TFEC	28	3	31	2264.493
#15	TCF12	27	8	35	1585.492
#16	ELK3	27	10	37	3760.362
#17	ELF1	26	8	34	1733.313
#18	ZFP36L2	26	8	34	1290.236
#19	PRDM2	25	5	30	995.792
#20	CEBPD	25	4	29	943.555
#21	MYT1L	25	2	27	260.012
#22	ELF4	24	7	31	724.907
#23	HLF	24	6	30	823.376
#24	MYCN	24	5	29	1466.698
#25	TAF4	24	4	28	1022.515
#26	BCL3	24	3	27	664.839
#27	ZNF207	24	4	28	685.512
#28	MAFB	23	6	29	1129.134
#29	SOX2	22	10	32	2144.887
#30	HMGB2	22	4	26	1361.842
#31	HCLS1	22	3	25	871.103
#32	STAT3	22	8	30	3711.489
#33	HNRNPAB	21	9	30	1661.18
#34	ADNP	21	8	29	836.394
#35	MMP14	21	10	31	2388.394
#36	CREBBP	21	5	26	1757.266
#37	E2F3	21	9	30	1528.536
#38	PTTG1	21	1	22	75.735
#39	ZNF238	21	7	28	619.944
#40	PBX1	21	11	32	2876.406
#41	PLSCR1	20	6	26	2026.003
#42	TRIM22	20	9	29	1435.218
#43	RFXANK	20	9	29	1427.219
#44	VAV1	20	2	22	105.838
#45	ZNF217	20	4	24	621.117
#46	CBFB	19	3	22	256.93
#47	RARG	19	4	23	384.303
#48	CSRNP3	19	8	27	565.119
#49	MYT1	19	5	24	936.978
#50	NOTCH1	19	8	27	570.906
#51	HDAC1	19	5	24	1296.616
#52	GCFC1	19	8	27	2278.511
#53	FUBP1	18	12	30	2192.573
#54	SOX15	18	0	18	0
#55	TFCP2	18	2	20	1540.46
#56	FLI1	18	8	26	8779.648
#57	MYOG	18	1	19	8.675
#58	HNF1B	18	7	25	2131.533
#59	GAS7	18	7	25	3524.029
#60	ENO1	18	6	24	2442.222
#61	GTF2I	18	5	23	1162.227
#62	EVX1	17	5	22	2271.693
#63	FOSL2	17	6	23	418.151
#64	SALL2	17	4	21	545.19
#65	BUD31	17	8	25	2186.122
#66	C11orf9	17	6	23	743.835
#67	HSF2	17	8	25	2623.444
#68	TP63	17	6	23	906.144
#69	ZNF85	17	8	25	979.526
#70	TFAP4	17	8	25	1513.361
#71	NPAT	16	9	25	2484.389
#72	SNAPC5	16	8	24	551.482
#73	ALS2CR8	16	5	21	455.211
#74	ARNT2	16	13	29	1799.211
#75	ETV5	16	9	25	1782.04
#76	GTF2H4	16	8	24	1570.257
#77	PCGF2	16	5	21	1358.145
#78	STAT4	16	6	22	498.964
#79	SP3	16	8	24	1417.4
#80	CREBZF	16	8	24	3132.557
#81	KDM5B	16	5	21	3877.848
#82	ATF2	16	6	22	2948.225
#83	STAT5B	16	6	22	975.613
#84	ZNF93	16	8	24	1260.358
#85	ZNF3	16	8	24	767.541
#86	TGIF2	16	7	23	1746.922
#87	ZNF140	16	6	22	721.624
#88	MYC	15	9	24	2680.484
#89	ZHX2	15	9	24	1880.801
#90	RUNX1	15	9	24	446.518
#91	BACH1	15	11	26	3080.284
#92	ZNF232	15	11	26	3461.081
#93	LASS6	15	7	22	2099.764
#94	ATF5	15	6	21	520.295
#95	ZEB1	15	10	25	1411.186
#96	CTCF	15	8	23	930.769
#97	ZGPAT	15	8	23	2300.692
#98	TCF7L1	15	9	24	524.84
#99	IRF7	15	9	24	3968.765
#100	SPEN	15	8	23	3552.1
#101	ZNF444	15	7	22	1549.389
#102	RXRB	15	4	19	250.634
#103	PITX3	15	4	19	508.17
#104	FOS	15	7	22	875.162
#105	HOXC4	15	9	24	1100.591
#106	FOXO4	14	6	20	1846.219
#107	MNT	14	15	29	2958.12
#108	HSF4	14	6	20	835.063
#109	NR3C1	14	6	20	2711.797
#110	CREB3L2	14	9	23	993.268
#111	KLF10	14	9	23	1824.341
#112	BARX1	14	3	17	82.393
#113	EMX1	14	7	21	2910.827
#114	BTAF1	14	8	22	1543.267
#115	HOXD4	14	8	22	965.725
#116	REST	14	4	18	3078.163
#117	HOXB7	14	8	22	1907.107
#118	MLL	14	9	23	767.301
#119	MTA1	13	12	25	1985.3
#120	ZNF175	13	7	20	2228.86
#121	MYBL2	13	5	18	2336.44
#122	SNAPC2	13	4	17	2117.444
#123	GLI2	13	12	25	3953.784
#124	HAND2	13	5	18	241.609
#125	STAT6	13	11	24	3624.597
#126	E2F6	13	12	25	2039.843
#127	BHLHE40	13	8	21	1810.206
#128	CREB5	13	7	20	3075.078
#129	TBR1	13	4	17	178.737
#130	ARNTL2	13	10	23	3893.719
#131	MGA	13	8	21	2877.794
#132	E2F5	13	10	23	2979.461
#133	TCF15	13	3	16	52.913
#134	SOX11	13	7	20	485.627
#135	MLXIPL	13	3	16	1203.447
#136	TAF5	13	9	22	1596.367
#137	VAX2	13	8	21	683.22
#138	HOXD11	12	7	19	3433.433
#139	SNAI2	12	12	24	2287.2
#140	PFDN1	12	8	20	790.382
#141	ZFP37	12	11	23	915.101
#142	MSC	12	8	20	2935.97
#143	MYCL1	12	10	22	2408.042
#144	PRRX1	12	14	26	4713.179
#145	RAX	12	7	19	556.274
#146	TSC22D1	12	13	25	1597.711
#147	HOXD3	12	8	20	855.566
#148	LHX6	12	7	19	182.737
#149	ETV7	12	6	18	516.402
#150	ZNF45	12	9	21	1912.638
#151	HDAC2	12	7	19	1250.244
#152	JUNB	12	8	20	626.933
#153	HEY1	12	7	19	1304.718
#154	NPAS1	12	7	19	920.813
#155	NFIB	12	14	26	1516.252
#156	SMAD6	12	6	18	222.874
#157	STAT2	12	9	21	1745.257
#158	TEAD3	12	15	27	2455.301
#159	NR1D2	11	10	21	2660.431
#160	ETV1	11	9	20	901.527
#161	UBN1	11	5	16	2965.096
#162	SPI1	11	9	20	1527.422
#163	SMAD4	11	9	20	1890.547
#164	HOXA10	11	7	18	1580.26
#165	SOX9	11	11	22	1764.72
#166	IRF3	11	8	19	935.38
#167	KLF6	11	11	22	1246.541
#168	PA2G4	11	7	18	522.78
#169	TSC22D3	11	9	20	3351.171
#170	NR2C1	11	12	23	3534.408
#171	AHR	11	13	24	728.881
#172	ATF3	11	9	20	941.588
#173	IRF1	11	14	25	1497.607
#174	NR2E1	11	17	28	3496.601
#175	ESRRG	11	12	23	690.955
#176	CBFA2T2	10	14	24	1670.775
#177	NFAT5	10	5	15	437.478
#178	HR	10	10	20	1449.279
#179	E2F4	10	9	19	3191.628
#180	HSF1	10	7	17	1281.822
#181	RB1	10	9	19	2273.975
#182	NR4A1	10	5	15	1375.569
#183	PHF1	10	9	19	1110.786
#184	TWIST1	10	10	20	1959.182
#185	ZNF117	10	11	21	488.595
#186	GATAD1	10	7	17	1139.036
#187	HOXA5	10	13	23	1512.234
#188	HHEX	10	8	18	1649.444
#189	HOXD9	10	8	18	530.908
#190	HMX1	10	5	15	669.318
#191	RCAN1	10	15	25	1824.06
#192	REL	10	11	21	2116.686
#193	GTF2H3	10	7	17	1603.109
#194	CREBL2	10	10	20	953.098
#195	DMTF1	10	10	20	2096.087
#196	MEF2A	10	13	23	4434.919
#197	NFYC	10	9	19	1815.907
#198	HMG20B	10	6	16	142.355
#199	PURA	10	6	16	654.452
#200	CUX1	10	11	21	852.32
#201	POU2F1	10	14	24	2288.417
#202	ZBTB48	10	9	19	1161.014
#203	RNF4	10	7	17	3735.172
#204	AEBP1	10	15	25	1238.527
#205	RERE	10	5	15	329.668
#206	ZNF202	10	11	21	1909.445
#207	STAT1	9	10	19	2360.465
#208	NFIL3	9	13	22	1588.533
#209	FBXW7	9	10	19	2344.843
#210	CSDA	9	11	20	1781.282
#211	HOXA9	9	6	15	1173.44
#212	MEOX2	9	13	22	1355.766
#213	POU3F1	9	13	22	2184.515
#214	NR3C2	9	10	19	2210.694
#215	PAX6	9	10	19	1457.132
#216	ZSCAN18	9	9	18	1155.04
#217	BHLHE41	9	12	21	1366.439
#218	PKNOX2	9	10	19	1504.586
#219	ZNF83	9	10	19	948.253
#220	ETS2	9	13	22	1242.8
#221	NR0B1	9	9	18	3655.072
#222	NFKB1	9	10	19	1455.227
#223	JUND	9	9	18	1265.532
#224	POU3F2	9	12	21	4929.814
#225	GABPA	9	8	17	694.686
#226	SLC2A4RG	9	11	20	2483.936
#227	RELB	9	8	17	257.529
#228	NFE2L1	9	8	17	844.834
#229	ZNF193	9	12	21	1018.068
#230	CBFA2T3	9	7	16	203.019
#231	ATF1	9	10	19	1270.293
#232	ZNF24	9	5	14	203.367
#233	TBX2	9	11	20	2275.129
#234	SUPT4H1	9	9	18	1371.458
#235	NFATC3	9	11	20	1995.859
#236	NFYB	9	8	17	777.162
#237	MLLT10	9	9	18	2411.682
#238	GATAD2A	9	16	25	2370.31
#239	BCL11B	9	10	19	9526.047
#240	WNT5A	9	13	22	2041.401
#241	BACH2	8	13	21	1112.832
#242	TEAD1	8	5	13	1030.877
#243	PRRX2	8	7	15	6715.638
#244	MAFF	8	9	17	1568.695
#245	CUX2	8	9	17	640.521
#246	HOXD1	8	9	17	1116.718
#247	CDX2	8	6	14	6071.03
#248	SOX13	8	15	23	5752.35
#249	SALL1	8	17	25	1640.355
#250	HOPX	8	11	19	3260.213
#251	ZNF274	8	14	22	2512.058
#252	ZKSCAN1	8	8	16	1332.94
#253	ZKSCAN5	8	12	20	1356.828
#254	PITX1	8	13	21	3875.214
#255	NCOR1	8	13	21	2813.341
#256	STAT5A	8	15	23	1210.581
#257	TADA3	8	13	21	1476.091
#258	SREBF2	8	13	21	705.223
#259	IRF6	8	5	13	887.538
#260	BCL6	8	11	19	2559.996
#261	NKX2-5	8	13	21	2507.487
#262	ESRRA	8	6	14	91.377
#263	NOLC1	8	9	17	2957.635
#264	E4F1	8	9	17	1815.046
#265	KLF4	8	7	15	1024.134
#266	FOXJ1	8	8	16	2240.723
#267	RUNX3	8	12	20	1036.148
#268	POU4F1	8	8	16	3270.582
#269	JUN	8	12	20	604.171
#270	ZNF323	8	9	17	1175.469
#271	MNX1	7	11	18	1293.668
#272	TCF20	7	10	17	782.97
#273	KDM5A	7	8	15	1478.238
#274	TAF7	7	7	14	521.863
#275	TFAP2A	7	16	23	880.482
#276	RELA	7	8	15	1049.412
#277	HOXC10	7	11	18	2373.749
#278	ZNF277	7	11	18	885.974
#279	TSC22D4	7	16	23	2546.075
#280	CNOT8	7	11	18	1685.063
#281	HOXB6	7	11	18	1495.713
#282	SOX12	7	13	20	784.144
#283	ZFHX3	7	13	20	1804.042
#284	MBD1	7	13	20	1775.659
#285	NEUROD2	7	9	16	380.772
#286	CNOT7	7	13	20	2036.215
#287	TFEB	7	8	15	1057.412
#288	BRD8	7	13	20	606.098
#289	GATA3	7	12	19	2343.173
#290	PROX1	7	10	17	1510.296
#291	NFIX	7	8	15	1098.365
#292	ETV4	7	15	22	3697.255
#293	ZNF189	7	9	16	744.323
#294	EN1	7	8	15	728.365
#295	HIF1A	7	13	20	1205.204
#296	NFX1	7	10	17	3822.231
#297	HOXA1	7	10	17	1819.009
#298	RCOR1	7	11	18	1021.581
#299	E2F1	7	3	10	352.562
#300	DDIT3	7	8	15	2733.305
#301	HMG20A	7	13	20	2069.019
#302	MEF2D	7	8	15	321.235
#303	SMAD5	7	10	17	2844.877
#304	ZNF135	7	11	18	1072.531
#305	IRF2	7	8	15	576.609
#306	HES1	7	12	19	1741.596
#307	IRF5	7	7	14	1221.428
#308	FOXD1	7	18	25	3641.331
#309	TARDBP	7	12	19	742.747
#310	STRN3	7	9	16	277.38
#311	KLF11	7	12	19	1406.569
#312	VDR	7	7	14	392.988
#313	TFDP2	6	12	18	579.522
#314	FOSB	6	3	9	597.402
#315	ZNF91	6	12	18	1844.503
#316	HMGA2	6	10	16	3057.666
#317	CREM	6	16	22	5130.736
#318	LZTS1	6	11	17	1553.462
#319	TFDP1	6	12	18	1815.533
#320	AFF1	6	10	16	968.268
#321	HMGA1	6	10	16	1560.957
#322	TRPS1	6	10	16	945.457
#323	TRIM28	6	11	17	950.932
#324	RBCK1	6	11	17	212.301
#325	LASS2	6	16	22	1912.249
#326	ZNF148	6	9	15	907.234
#327	SMAD2	6	14	20	3311.653
#328	HMGB1	6	9	15	255.616
#329	GTF2IRD1	6	5	11	1575.738
#330	TCF25	6	13	19	2835.457
#331	YY1	6	8	14	2064.904
#332	ECSIT	6	8	14	765.1
#333	UBP1	6	6	12	278.571
#334	NR1H3	6	7	13	3349.466
#335	ZIC3	6	8	14	2159.176
#336	SNAPC4	6	8	14	1692.034
#337	KLF12	6	13	19	2190.321
#338	FEV	6	7	13	2396.816
#339	SIX6	6	10	16	1010.045
#340	TAF6	5	10	15	1260.379
#341	SIX1	5	11	16	662.321
#342	HOXD10	5	11	16	935.068
#343	ZFPM2	5	13	18	518.646
#344	MITF	5	13	18	866.99
#345	EDF1	5	9	14	1682.531
#346	ERG	5	5	10	457.467
#347	TFCP2L1	5	9	14	987.74
#348	ZNF167	5	14	19	1261.839
#349	FOXF2	5	6	11	387.935
#350	ARNTL	5	10	15	975.364
#351	LHX2	5	18	23	1454.42
#352	CREB3	5	10	15	1492.323
#353	TFAM	5	15	20	2122.729
#354	TAF12	5	13	18	1586.858
#355	FOXN3	5	11	16	940.825
#356	NPAS2	5	16	21	1541.383
#357	NFATC1	5	10	15	1343.319
#358	ZNF500	5	12	17	1525.091
#359	ZNF268	5	4	9	99.921
#360	ST18	5	5	10	1174.398
#361	RBPJ	5	14	19	705.572
#362	HIRA	5	10	15	631.547
#363	BTG2	5	10	15	1041.999
#364	SUPT6H	5	9	14	606.612
#365	MAF	5	13	18	823.262
#366	KLF9	5	12	17	857.259
#367	NFE2L3	5	13	18	918.476
#368	EGR4	5	11	16	3523.763
#369	TCF7L2	5	10	15	1357.178
#370	SATB2	5	11	16	1332.747
#371	TBP	5	9	14	225.916
#372	GABPB1	5	13	18	1424.384
#373	LEF1	5	14	19	697.163
#374	MEIS2	5	12	17	5332.015
#375	USF2	5	12	17	453.943
#376	NR1H2	5	9	14	1096.197
#377	EGR3	5	8	13	1209.553
#378	EGR2	5	8	13	992.089
#379	HOXA4	5	10	15	1563.107
#380	EPAS1	4	12	16	1605.159
#381	PBX2	4	13	17	1541.317
#382	PLAGL2	4	12	16	2087.907
#383	CLOCK	4	14	18	1443.908
#384	SOX10	4	9	13	635.941
#385	C2orf3	4	10	14	1795.343
#386	MSRB2	4	10	14	662.243
#387	MSX1	4	11	15	1196.295
#388	MEOX1	4	4	8	220.365
#389	SIX3	4	11	15	1182.149
#390	NR4A2	4	14	18	431.412
#391	PHTF1	4	11	15	759.484
#392	XBP1	4	11	15	627.24
#393	EGR1	4	11	15	1014.22
#394	RXRA	4	11	15	2052.349
#395	NFE2L2	4	14	18	329.128
#396	KLF2	4	6	10	206.725
#397	RUNX1T1	4	11	15	863.093
#398	EN2	4	12	16	643.679
#399	SIM2	4	7	11	669.931
#400	FOXF1	4	12	16	2288.764
#401	ZNF281	4	12	16	1857.921
#402	NFIC	4	9	13	339.972
#403	FOXG1	4	13	17	1055.642
#404	FOXC1	4	14	18	1286.398
#405	TCF4	4	13	17	1468.933
#406	MEIS3P1	4	17	21	2892.436
#407	NR2F6	4	9	13	354.172
#408	TCFL5	4	13	17	364.467
#409	MLX	4	17	21	846.982
#410	SRF	4	12	16	950.708
#411	PBX3	4	14	18	730.595
#412	FOXA2	4	9	13	4386.205
#413	ZFP36L1	4	20	24	2057.798
#414	POU6F1	4	14	18	431.195
#415	ARID4A	3	13	16	1672.01
#416	SCAND1	3	11	14	381.89
#417	PLAG1	3	9	12	2549.254
#418	SLC30A9	3	11	14	1991.267
#419	NEUROD1	3	13	16	1976.53
#420	FOXO1	3	12	15	819.85
#421	GLI3	3	9	12	694.122
#422	FOXO3	3	9	12	340.845
#423	MZF1	3	10	13	1152.344
#424	RARA	3	10	13	1012.185
#425	ZNF394	3	11	14	238.112
#426	MEIS1	3	16	19	463.384
#427	CITED1	3	11	14	335.584
#428	BATF	3	16	19	1654.254
#429	FOSL1	3	14	17	1095.45
#430	MAX	3	7	10	592.499
#431	NANOG	3	10	13	1494.508
#432	ELF2	3	15	18	480.796
#433	ZNF133	3	9	12	184.332
#434	ZNF187	3	13	16	1378.797
#435	NR2F1	2	14	16	455.202
#436	HEY2	2	11	13	214.295
#437	CTBP1	2	9	11	214.393
#438	CNBP	2	14	16	312.508
#439	ZHX3	2	11	13	251.075
#440	TP53	2	13	15	67.255
#441	HMBOX1	2	8	10	174.198
#442	DBP	2	12	14	294.028
#443	TSC22D2	2	12	14	2116.432
#444	ZEB2	2	19	21	442.807
#445	SMAD9	2	13	15	509.512
#446	MECOM	2	12	14	289.314
#447	AR	2	15	17	830.646
#448	ELK1	2	12	14	442.36
#449	RFX5	2	10	12	214.144
#450	FOXJ3	2	11	13	525.89
#451	CDKN2A	2	17	19	2364.511
#452	SCML2	2	12	14	271.505
#453	ADNP2	2	8	10	533.492
#454	HIF3A	2	12	14	733.365
#455	ERF	2	14	16	2810.74
#456	SCML1	2	8	10	610.924
#457	RORA	2	12	14	2536.742
#458	NR4A3	2	14	16	439.311
#459	CREB1	2	9	11	78.493
#460	CREB3L1	2	11	13	277.09
#461	CEBPA	2	10	12	1355.819
#462	SOLH	2	12	14	194.512
#463	IRX5	2	15	17	1352.41
#464	ZNF219	2	9	11	152.572
#465	CSRNP2	2	15	17	162.692
#466	TEAD4	2	8	10	320.965
#467	SOX5	2	15	17	259.899
#468	BATF3	2	10	12	1236.641
#469	RORB	2	12	14	610.856
#470	LMO4	2	16	18	1878.783
#471	IRF9	1	6	7	1127.953
#472	FOXJ2	1	12	13	191.297
#473	FOXK2	1	13	14	1648.042
#474	NFKB2	1	12	13	80.758
#475	CTNNB1	1	11	12	623.586
#476	TAF13	1	7	8	61.772
#477	SREBF1	1	19	20	415.087
#478	RARB	1	13	14	91.686
#479	HOXA11	1	16	17	201.958
#480	SOX21	1	11	12	37.065
#481	HOXB2	1	14	15	433.321
#482	ATF6	1	10	11	911.014
#483	ZBTB38	1	15	16	174.803
#484	CITED2	1	11	12	181.474
#485	KLF7	1	7	8	273.924
#486	TFE3	1	11	12	1111.955
#487	ZNF131	1	12	13	287.784
#488	TCF7	1	15	16	360.98
#489	ZIC1	1	18	19	1492.578
#490	ZXDC	1	10	11	57.991
#491	MAFG	1	10	11	481.389
#492	NR2F2	0	18	18	0
#493	SMAD1	0	15	15	0
#494	TCEAL1	0	10	10	0
#495	DLX2	0	7	7	0
#496	KLF3	0	12	12	0
#497	ZFHX4	0	15	15	0
#498	SMAD3	0	9	9	0
#499	ATF4	0	9	9	0
#500	AATF	0	12	12	0