Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NFIA	85	2	87	348.578
#2	FOSL1	76	6	82	249.182
#3	SNAI2	58	9	67	591.002
#4	SOX8	55	3	58	242.635
#5	SOX6	53	2	55	261.367
#6	AEBP1	52	10	62	1002.247
#7	HOPX	49	11	60	484.34
#8	ASCL1	49	7	56	431.765
#9	WNT5A	48	10	58	1452.705
#10	E2F7	48	13	61	2792.561
#11	SOX2	47	9	56	3373.724
#12	PEG3	46	8	54	624.037
#13	LHX2	46	6	52	4243.74
#14	BTG2	46	7	53	297.18
#15	SALL2	45	6	51	345.156
#16	ARNT2	45	7	52	1268.83
#17	TCF4	45	9	54	1123.496
#18	SOX9	44	9	53	969.016
#19	SOX11	43	13	56	14141.998
#20	HCLS1	42	5	47	437.848
#21	SMAD1	42	11	53	429.028
#22	ZSCAN18	42	6	48	500.48
#23	CSRNP3	41	10	51	1518.254
#24	SLC2A4RG	39	11	50	1638.645
#25	KLF15	38	6	44	550.901
#26	GABPB1	37	9	46	3300.345
#27	SUPT6H	37	7	44	1681.176
#28	ZIC1	37	8	45	5635.689
#29	CREB5	37	8	45	1307.519
#30	ETV1	37	12	49	505.262
#31	POU3F2	34	8	42	372.026
#32	PROX1	33	9	42	429.621
#33	FOXC2	33	7	40	1724.662
#34	FOXD1	33	11	44	3464.08
#35	FOXO6	32	8	40	1887.968
#36	TFDP1	31	13	44	4169.061
#37	SMAD6	31	11	42	593.058
#38	LZTS1	31	15	46	4346.591
#39	ETS1	31	9	40	1179.338
#40	TWIST1	31	11	42	1822.865
#41	HES6	30	13	43	1622.788
#42	TBX3	29	13	42	441.975
#43	MYCN	29	10	39	1540.268
#44	OLIG2	29	7	36	397.333
#45	HEY1	28	17	45	2638.192
#46	ARX	28	9	37	327.572
#47	IRF8	28	3	31	71.852
#48	HOXD8	28	10	38	1681.42
#49	BACH2	28	10	38	519.796
#50	HOXA3	28	3	31	875.025
#51	HEY2	28	7	35	174.268
#52	TFAP2A	28	11	39	998.725
#53	TWIST2	28	8	36	246.201
#54	SALL1	28	17	45	10848.303
#55	EBF1	28	10	38	3411.923
#56	BCL6	27	7	34	1386.417
#57	HOXA5	27	5	32	548.163
#58	NFYA	27	10	37	913.847
#59	HMGA1	27	9	36	680.351
#60	ZHX2	26	13	39	681.546
#61	MEF2C	26	12	38	527.515
#62	PBX1	26	11	37	1579.181
#63	AHR	26	11	37	2013.065
#64	MEIS1	25	18	43	1229.673
#65	FOXO1	25	14	39	2596.233
#66	PKNOX2	25	11	36	279.608
#67	E2F5	25	13	38	692.819
#68	DLX2	25	10	35	1214.393
#69	PRRX1	24	13	37	4464.37
#70	ZNF174	24	12	36	686.021
#71	ZFP36L2	24	11	35	487.6
#72	IRX5	23	12	35	12782.301
#73	CTNNB1	23	12	35	3717.744
#74	CREB3L1	23	11	34	1514.595
#75	ZNF167	23	12	35	1021.258
#76	ETS2	23	8	31	760.127
#77	FOXF2	22	14	36	2816.931
#78	CEBPA	22	13	35	1030.463
#79	ZNF138	22	12	34	964.144
#80	NR2F1	22	19	41	3659.408
#81	ZNF91	22	11	33	2271.782
#82	ISL2	22	11	33	1498.835
#83	ZNF140	21	8	29	694.056
#84	CITED2	21	14	35	795.387
#85	STAT6	21	13	34	1489.973
#86	FOXM1	21	11	32	311.686
#87	SMAD3	21	15	36	1236.364
#88	CITED1	21	12	33	948.732
#89	FOXS1	20	12	32	1958.959
#90	PRDM1	20	12	32	1179.512
#91	HOXB6	20	14	34	698.117
#92	HOXA7	20	9	29	588.266
#93	HHEX	20	8	28	2306.897
#94	RARG	19	11	30	334.265
#95	TFAP2C	19	12	31	390.334
#96	PITX1	19	15	34	895.284
#97	NKX3-1	19	12	31	144.018
#98	GAS7	19	13	32	426.373
#99	IRF7	19	8	27	3555.963
#100	MYT1	19	8	27	251.033
#101	IRX3	19	15	34	2590.267
#102	SOX10	19	14	33	1889.895
#103	SOX1	19	11	30	793.805
#104	FLI1	19	12	31	1956.169
#105	DLX1	19	10	29	6134.452
#106	NFE2L3	19	16	35	1412.031
#107	HNF4G	19	11	30	486.06
#108	ELF4	18	8	26	65.88
#109	POU3F3	18	10	28	289.181
#110	ZEB1	18	15	33	2139.729
#111	ZIC2	18	15	33	1573.614
#112	SATB1	18	14	32	1262.731
#113	ETV4	18	19	37	6780.305
#114	SOX5	18	5	23	91.004
#115	HOXB7	18	10	28	990.71
#116	HES1	18	15	33	12424.282
#117	CEBPD	18	10	28	431.249
#118	LASS6	18	13	31	3511.097
#119	HOXC10	18	12	30	1337.955
#120	FOXG1	17	18	35	27169.629
#121	ZNF83	17	5	22	1788.017
#122	ZNF256	17	10	27	1900.352
#123	NR2F2	17	12	29	3881.205
#124	ETV5	17	19	36	745.247
#125	RUNX1T1	16	13	29	2337.429
#126	MAFB	16	18	34	2000.757
#127	MAFK	16	10	26	194.263
#128	HOXA9	16	8	24	1393.128
#129	FOXL1	16	12	28	675.007
#130	GATA6	16	10	26	1108.393
#131	MECOM	16	14	30	773.853
#132	GATAD2B	16	15	31	581.757
#133	SOX21	16	9	25	440.452
#134	ELK1	15	10	25	2665.622
#135	HES5	15	11	26	89.98
#136	C11orf9	15	11	26	927.921
#137	PAX6	15	14	29	1656.567
#138	AHCTF1	15	6	21	1357.426
#139	NEUROD2	15	14	29	3356.22
#140	EPAS1	15	18	33	1639.889
#141	FOS	15	14	29	1813.299
#142	RUNX3	15	12	27	2367.934
#143	ZNF75D	15	15	30	4700.977
#144	HOXD11	15	10	25	2729.533
#145	PPARG	14	9	23	497.381
#146	EGR1	14	7	21	928.629
#147	GATA3	14	17	31	849.273
#148	VDR	14	15	29	362.3
#149	HIC1	14	15	29	2592.432
#150	IKZF1	14	9	23	119.149
#151	ATF2	14	15	29	8595.627
#152	HOXB9	14	15	29	967.686
#153	LHX6	14	17	31	4929.079
#154	HOXB3	14	11	25	1056.245
#155	MSC	14	10	24	627.952
#156	NR2E1	14	8	22	222.243
#157	VAV1	14	10	24	1551.046
#158	HMBOX1	14	11	25	725.98
#159	TRIM22	14	14	28	3775.744
#160	SIX5	14	11	25	3141.965
#161	LMO4	14	11	25	143.196
#162	POU2F2	13	9	22	394.633
#163	FOXF1	13	15	28	2703.664
#164	EGR3	13	12	25	1418.188
#165	JUNB	13	16	29	1604.409
#166	ZNF193	13	16	29	6251.591
#167	MEOX2	13	20	33	874.677
#168	NKX3-2	13	14	27	666.924
#169	MAF	13	11	24	1241.625
#170	THRA	13	15	28	466.539
#171	HMGA2	13	8	21	265.995
#172	RUNX2	13	17	30	761.997
#173	FOXL2	13	13	26	799.122
#174	SPI1	13	15	28	1102.051
#175	KLF5	13	15	28	796.005
#176	FOXO3	12	9	21	640.488
#177	WT1	12	10	22	684.994
#178	EN1	12	17	29	2268.592
#179	HLF	12	13	25	562.258
#180	KLF4	12	13	25	2029.737
#181	NR2F6	12	12	24	1726.247
#182	E2F1	12	15	27	991.978
#183	TRERF1	12	9	21	2065.339
#184	BATF3	12	16	28	679.693
#185	ZNF135	12	11	23	614.38
#186	PITX2	12	9	21	364.87
#187	HOXB2	12	13	25	1306.517
#188	IRX1	12	11	23	831.563
#189	HOXC13	12	13	25	1573.277
#190	NR3C2	11	15	26	1647.056
#191	HOXC5	11	8	19	1206.32
#192	ZNF85	11	14	25	1054.032
#193	EN2	11	17	28	390.905
#194	ENO1	11	12	23	3419.955
#195	SIX6	11	13	24	1814.313
#196	TFCP2L1	11	12	23	1125.608
#197	POU3F1	11	14	25	910.541
#198	HOXD10	11	10	21	473.34
#199	CDKN2A	11	17	28	1644.628
#200	ZIC3	11	10	21	615.962
#201	MYBL2	11	9	20	371.282
#202	NR0B1	11	14	25	1935.836
#203	ZNF3	11	14	25	1533.607
#204	KLF9	11	16	27	1104.202
#205	ARNT	11	14	25	348.746
#206	SCAND1	11	12	23	1280.681
#207	TSHZ2	11	16	27	861.249
#208	FOSL2	11	10	21	482.671
#209	HOXA6	11	14	25	4174.365
#210	STAT5B	11	12	23	609.418
#211	NFE2L2	10	19	29	4334.938
#212	MMP14	10	12	22	544.706
#213	ZNF71	10	21	31	13055.774
#214	ONECUT2	10	15	25	234.682
#215	TAF4	10	9	19	702.374
#216	HOXA10	10	13	23	1055.516
#217	MYT1L	10	9	19	2114.997
#218	DMRT1	10	12	22	1275.715
#219	SMAD9	10	16	26	310.016
#220	KCNH8	10	18	28	2498.728
#221	MEF2D	10	9	19	396.916
#222	PGR	10	6	16	689.664
#223	ESRRG	10	16	26	295.817
#224	HNF4A	10	11	21	1765.717
#225	DLX6	10	15	25	1420.7
#226	DMRT2	10	12	22	545.672
#227	TBX5	10	15	25	1290.562
#228	RORA	10	17	27	1638.537
#229	ZNF19	10	9	19	1296.122
#230	NR4A2	10	19	29	1153.938
#231	DLX4	10	14	24	854.106
#232	LHX8	10	12	22	1165.141
#233	LEF1	10	12	22	770.594
#234	FOXN3	10	14	24	662.765
#235	STAT2	10	16	26	3477.703
#236	FOXA2	10	11	21	5115.841
#237	BCL3	10	13	23	324.63
#238	OVOL1	10	15	25	4173.341
#239	FOXC1	10	9	19	546.682
#240	SOX4	9	13	22	507.739
#241	VSX1	9	17	26	4463.419
#242	HOXA1	9	13	22	908.527
#243	ZXDC	9	15	24	207.909
#244	ZNF268	9	14	23	1085.701
#245	HOXD3	9	14	23	217.21
#246	TP73	9	15	24	667.81
#247	PLAG1	9	16	25	243.973
#248	ZFPM2	9	20	29	665.066
#249	NEUROD1	9	16	25	461.713
#250	CREM	9	18	27	374.252
#251	RARB	9	11	20	698.897
#252	MLX	9	14	23	1247.227
#253	ZNF154	9	11	20	388.383
#254	POU4F1	9	13	22	511.949
#255	NOTCH1	9	14	23	182.436
#256	TFDP2	9	11	20	626.933
#257	TCF7	9	9	18	998.799
#258	STRN3	9	17	26	2001.367
#259	TEAD2	9	16	25	2885.951
#260	EGR2	9	12	21	419.301
#261	ZNF93	9	15	24	3175.739
#262	NFATC2	9	14	23	423.827
#263	ARNTL2	9	11	20	200.903
#264	NFAT5	9	12	21	559.177
#265	ZNF483	8	11	19	1637.517
#266	ZNF165	8	17	25	796.336
#267	HOXA11	8	19	27	704.606
#268	TBX1	8	14	22	2909.861
#269	SIX1	8	18	26	468.503
#270	ALX1	8	14	22	681.262
#271	RFXAP	8	13	21	3158.495
#272	CSDA	8	9	17	209.548
#273	ZNF396	8	17	25	559.467
#274	NFIB	8	15	23	243.237
#275	NFKB2	8	17	25	264.124
#276	RXRG	8	14	22	1054.575
#277	FOXE1	8	13	21	4084.113
#278	ERF	8	13	21	4277.868
#279	TEAD4	8	16	24	1002.204
#280	FOXP1	8	8	16	247.63
#281	CREB3L2	8	11	19	162.799
#282	MNX1	8	19	27	598.019
#283	ZFP36L1	8	12	20	3810.521
#284	ZFP42	8	14	22	1951.641
#285	SPDEF	8	12	20	1452.034
#286	YY1	8	16	24	756.211
#287	GATA5	8	14	22	2029.259
#288	POU6F2	8	10	18	942.737
#289	PAX7	7	14	21	2210.112
#290	ATF3	7	15	22	708.025
#291	FUBP1	7	15	22	1321.967
#292	SOX13	7	12	19	422.073
#293	NFATC4	7	15	22	619.614
#294	SOX30	7	13	20	888.778
#295	EGR4	7	10	17	1502.14
#296	BHLHE40	7	12	19	232.499
#297	ZSCAN23	7	10	17	1366.911
#298	BLZF1	7	14	21	882.833
#299	ATF6B	7	13	20	1138.331
#300	NFATC1	7	15	22	871.978
#301	HOXD13	7	17	24	999.427
#302	LHX9	7	21	28	1404.363
#303	KLF17	7	16	23	1026.765
#304	IKZF3	7	14	21	1515.468
#305	GSX1	7	11	18	371.199
#306	RORB	7	15	22	470.329
#307	PBX4	7	20	27	1276.936
#308	NKX2-5	7	19	26	692.435
#309	ANKRD30A	7	16	23	1111.615
#310	ALS2CR8	7	12	19	516.589
#311	HCFC1	7	14	21	347.473
#312	ZNF117	7	12	19	250.628
#313	KDM5B	7	15	22	2450.396
#314	CBL	7	12	19	493.942
#315	MEOX1	7	13	20	280.198
#316	MLLT10	7	17	24	2514.851
#317	SOX15	7	13	20	298.648
#318	NR5A2	7	17	24	625.642
#319	HESX1	7	17	24	1317.583
#320	PCGF2	7	14	21	551.671
#321	SIM1	7	20	27	1260.83
#322	PPARD	7	18	25	1192.041
#323	SREBF1	7	14	21	1512.776
#324	TADA2A	6	11	17	853.944
#325	TFEC	6	10	16	158.108
#326	FOSB	6	15	21	293.827
#327	NPAS2	6	21	27	1244.363
#328	BCL11B	6	14	20	2273.523
#329	HOXA2	6	10	16	271.309
#330	EHF	6	16	22	527.79
#331	POU1F1	6	19	25	814.389
#332	TFAP2B	6	15	21	727.71
#333	SMAD2	6	15	21	368.616
#334	THRB	6	20	26	686.217
#335	PTH	6	15	21	2257.617
#336	ERG	6	14	20	601.547
#337	SIX3	6	13	19	1118.413
#338	TCF7L2	6	20	26	1044.149
#339	TBX2	6	10	16	516.046
#340	ZSCAN12	6	16	22	2198.645
#341	ETV6	6	15	21	3983.468
#342	ZNF33B	6	14	20	12757.773
#343	DLX3	6	7	13	167.858
#344	REST	6	13	19	521.532
#345	NCOR1	6	17	23	1296.305
#346	ZEB2	6	20	26	1811.928
#347	SOX18	6	18	24	1178.654
#348	TAL1	6	10	16	228.805
#349	GATA2	6	20	26	1244.464
#350	ZNF444	6	12	18	1080.167
#351	ZNF639	6	13	19	2730.4
#352	MTA2	6	13	19	185.991
#353	MESP1	6	17	23	1423.105
#354	ZNF207	6	15	21	2915.102
#355	RERE	6	15	21	1918.506
#356	E2F2	6	11	17	567.177
#357	L3MBTL4	6	13	19	414.762
#358	ZHX3	6	11	17	155.283
#359	TULP4	6	12	18	1453.535
#360	C2orf3	6	16	22	1188.539
#361	IKZF4	6	14	20	1552.524
#362	NRL	6	13	19	1027.54
#363	ATOH1	6	12	18	1111.596
#364	FOXJ1	6	12	18	386.769
#365	GATA1	6	14	20	5556.73
#366	ZNF500	6	11	17	786.12
#367	NKX2-8	6	12	18	1347.033
#368	HNF1A	6	13	19	7235.846
#369	FOXO4	6	15	21	1232.927
#370	SIN3A	6	12	18	2098.174
#371	NFIX	6	11	17	1489.261
#372	TLX3	5	14	19	767.504
#373	TP63	5	10	15	18105.411
#374	T	5	11	16	75.641
#375	KDM5A	5	12	17	644.328
#376	PPARA	5	15	20	884.953
#377	GATA4	5	10	15	1906.902
#378	NANOG	5	12	17	171.042
#379	RCOR1	5	14	19	690.534
#380	HSF5	5	10	15	1311.173
#381	RUNX1	5	16	21	500.541
#382	C12orf28	5	18	23	592.06
#383	ETV7	5	14	19	535.051
#384	NPAT	5	14	19	1177.687
#385	ONECUT1	5	11	16	1212.937
#386	HOXD4	5	12	17	746.576
#387	TLX2	5	10	15	130.695
#388	SPIB	5	13	18	924.738
#389	NR4A3	5	15	20	390.443
#390	HR	5	17	22	769.129
#391	NKX2-3	5	14	19	615.032
#392	ST18	5	13	18	1370.065
#393	ZNF215	5	15	20	1062.131
#394	HOXA13	5	16	21	337.795
#395	PRRX2	5	12	17	720.375
#396	PRDM2	5	10	15	451.947
#397	NR4A1	5	15	20	2729.034
#398	MSX2	5	8	13	194.625
#399	ZNF287	4	10	14	272.93
#400	RARA	4	8	12	936.708
#401	NEUROG1	4	12	16	1319.678
#402	IRF1	4	18	22	466.619
#403	MYF5	4	12	16	5368.21
#404	VTN	4	12	16	1235.714
#405	ZNF24	4	13	17	1245.567
#406	RAX2	4	14	18	339.549
#407	BRD8	4	14	18	2745.981
#408	GLI2	4	9	13	677.664
#409	FOXP3	4	16	20	762.033
#410	ESX1	4	12	16	557.182
#411	STAT1	4	15	19	399.762
#412	SNAI3	4	15	19	1028.26
#413	ELF5	4	11	15	595.047
#414	FOXA1	4	17	21	1231.512
#415	GSC2	4	13	17	582.114
#416	MGA	4	15	19	422.629
#417	IRX4	4	15	19	1748.483
#418	CREBBP	4	14	18	388.896
#419	LHX1	4	14	18	595.289
#420	FOXD3	4	16	20	283.361
#421	NKX2-1	4	12	16	275.165
#422	FOXP2	4	16	20	2152.932
#423	HIRA	4	13	17	1148.653
#424	NR2E3	4	16	20	3235.423
#425	PLSCR1	4	11	15	910.06
#426	LASS5	4	13	17	1022.952
#427	POU5F1B	4	13	17	168.784
#428	MEIS3	4	20	24	1054.093
#429	ESRRB	4	5	9	70.05
#430	MLL	4	11	15	4346.303
#431	ELK4	4	17	21	1404.048
#432	HMGB2	4	13	17	314.823
#433	NR6A1	4	13	17	304.985
#434	SIM2	4	9	13	90.073
#435	HMG20B	4	16	20	577.9
#436	SIX4	4	14	18	418.89
#437	ZNF90	4	18	22	1479.878
#438	SCRT1	4	14	18	484.488
#439	NKX6-2	4	8	12	464.043
#440	MITF	4	16	20	2056.557
#441	ZSCAN2	4	13	17	160.25
#442	KLF12	3	13	16	94.576
#443	CREBZF	3	14	17	463.657
#444	ALX3	3	10	13	739.452
#445	MYNN	3	19	22	913.733
#446	NANOGNB	3	10	13	178.927
#447	ZIC5	3	9	12	316.889
#448	ZFHX3	3	7	10	163.146
#449	GLI3	3	16	19	1009.635
#450	ZNF80	3	15	18	1278.779
#451	TSC22D1	3	10	13	137.913
#452	HNRNPAB	3	16	19	858.062
#453	NFE2	3	12	15	954.658
#454	FOXH1	3	10	13	203.779
#455	ZNF81	3	13	16	272.938
#456	NPAS1	3	15	18	1334.988
#457	POU2F3	3	10	13	4523.546
#458	IRX2	3	12	15	400.092
#459	ZSCAN4	3	13	16	563.588
#460	IRF4	3	18	21	574.936
#461	SNAPC5	3	11	14	819.719
#462	TRIM29	3	13	16	379.327
#463	BNC1	3	13	16	436.167
#464	GBX2	3	13	16	199.672
#465	PBX3	3	13	16	1725.252
#466	NR1I3	3	15	18	2073.661
#467	KLF16	3	17	20	1607.423
#468	ESR2	3	12	15	1060.076
#469	TBX20	3	13	16	5426.265
#470	MXD1	2	19	21	1119.272
#471	MKX	2	12	14	2047.629
#472	SCAND2	2	18	20	202.6
#473	ESR1	2	8	10	119.524
#474	ZNF157	2	10	12	148.998
#475	GRHL3	2	19	21	392.992
#476	HIF3A	2	14	16	661.404
#477	CUX2	2	12	14	176.314
#478	NR1H4	2	16	18	628.207
#479	JUND	2	15	17	280.231
#480	SPIC	2	14	16	533.336
#481	HOXA4	2	13	15	313.941
#482	SLC26A3	2	18	20	748.244
#483	PAX3	2	16	18	452.99
#484	OTX2	2	12	14	1154.089
#485	CTBP1	2	13	15	387.116
#486	FOXN4	1	15	16	398.537
#487	CREB3L3	1	16	17	437.586
#488	DMBX1	1	12	13	126.052
#489	HOXD1	1	13	14	199.496
#490	ZSCAN20	1	12	13	217.89
#491	AFF4	1	15	16	130.339
#492	IRF6	1	17	18	260.78
#493	ELF3	1	17	18	116.637
#494	TEF	1	20	21	305.272
#495	TBX22	1	11	12	542.495
#496	TCF21	1	18	19	507.638
#497	NR5A1	1	15	16	90.332
#498	PAX8	0	15	15	0
#499	ZNF397	0	14	14	0
#500	ZFHX4	0	12	12	0