Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	CDKN2A	37	6	43	916.683
#2	ATF7	33	6	39	1230.37
#3	BACH1	31	7	38	635.028
#4	ELF1	31	5	36	1561.583
#5	ST18	31	6	37	1291.622
#6	SOX30	29	4	33	950.807
#7	AEBP1	29	7	36	561.743
#8	ZNF193	27	9	36	1384.525
#9	RORC	27	4	31	568.428
#10	SCAND1	27	8	35	1590.674
#11	MBD1	26	8	34	873.174
#12	MAX	26	5	31	1201.03
#13	TBX2	26	7	33	847.156
#14	MEIS3	26	9	35	1281.78
#15	ZNF367	25	2	27	521.588
#16	HOXC9	25	9	34	905.94
#17	GABPA	25	10	35	1053.745
#18	RXRB	25	6	31	573.008
#19	HSF1	25	11	36	1153.749
#20	ZFHX3	25	7	32	906.892
#21	NR0B1	24	5	29	972.995
#22	PPARA	24	11	35	1684.384
#23	CBFA2T2	23	12	35	1205.254
#24	UHRF1	23	4	27	1792.103
#25	TFDP1	23	20	43	2163.783
#26	ZIC1	23	13	36	1908.822
#27	ZNF41	23	5	28	514.729
#28	FOS	23	5	28	702.569
#29	MMP14	23	7	30	1119.842
#30	NFATC4	23	9	32	1343.988
#31	ZNF445	22	6	28	978.095
#32	PBX1	22	11	33	1687.141
#33	TAL1	22	10	32	1354.777
#34	GATA1	22	10	32	1079.765
#35	NFYA	22	7	29	508.846
#36	FOSL1	22	11	33	1744.968
#37	SPEN	22	8	30	993.417
#38	HOXB2	22	7	29	1516.448
#39	ARNT	22	10	32	923.075
#40	GTF2H4	21	7	28	1206.787
#41	SOX5	21	9	30	1254.383
#42	HOXA5	21	10	31	1772.897
#43	NKX3-1	21	9	30	1779.277
#44	BHLHE41	21	8	29	1213.465
#45	MYF5	21	7	28	1009.272
#46	ATF5	20	10	30	1132.175
#47	NR2E3	20	6	26	404.764
#48	TSHZ3	20	5	25	425.095
#49	DLX4	20	12	32	974.576
#50	OLIG2	20	10	30	1423.803
#51	TRIM29	20	7	27	996.508
#52	POU2F2	20	7	27	984.729
#53	TFCP2	20	8	28	1096.082
#54	FOXL1	20	12	32	1166.619
#55	MSX2	19	9	28	1086.415
#56	SOX9	19	8	27	1097.787
#57	ZNF197	19	13	32	2014.55
#58	ZNF215	19	10	29	1380.433
#59	BATF2	19	11	30	1278.21
#60	ZNF165	19	12	31	1887.791
#61	C11orf9	19	9	28	995.443
#62	POU4F1	19	12	31	1157.741
#63	TFAP2C	19	6	25	479.759
#64	ZNF3	18	12	30	1868.833
#65	SMAD9	18	6	24	766.326
#66	JUNB	18	3	21	377.062
#67	E2F8	18	3	21	138.071
#68	KDM5A	18	18	36	1937.832
#69	HOXA1	18	5	23	702.955
#70	HMG20B	18	14	32	1700.381
#71	TCF20	18	10	28	1160.936
#72	CBL	18	11	29	1322.341
#73	EGR4	18	6	24	812.485
#74	HCFC1	17	5	22	658.124
#75	PRRX1	17	9	26	1009.156
#76	NR3C2	17	15	32	1799.088
#77	MLLT10	17	13	30	1502.83
#78	ZIC2	17	11	28	1055.817
#79	PBX4	17	11	28	1132.385
#80	MLL	17	8	25	938.432
#81	STAT2	17	10	27	512.734
#82	CNOT7	17	8	25	623.746
#83	KLF15	17	13	30	1768.114
#84	FOXL2	17	10	27	954.887
#85	FOXD1	17	12	29	1599.903
#86	TULP4	17	13	30	1732.925
#87	ZSCAN1	17	9	26	1080.761
#88	E2F1	17	12	29	1781.361
#89	ZNF148	17	11	28	996.525
#90	PPARD	17	11	28	913.616
#91	HOXD4	17	8	25	626.414
#92	NFKB2	16	8	24	1348.212
#93	ONECUT3	16	13	29	1223.798
#94	TAF1B	16	11	27	1406.817
#95	MYBL2	16	7	23	831.895
#96	HOXA9	16	9	25	1311.288
#97	IKZF1	16	8	24	1118.355
#98	GSX2	16	13	29	1787.117
#99	ATF6	16	11	27	994.949
#100	PGBD1	16	7	23	1213.584
#101	SIX5	16	10	26	780.739
#102	ALX3	16	14	30	1924.076
#103	TEAD4	16	9	25	948.378
#104	RAX	16	13	29	1612.238
#105	ZEB1	16	13	29	1601.12
#106	STAT3	16	11	27	1596.844
#107	RUNX3	16	12	28	1188.614
#108	ASCL1	15	6	21	542.571
#109	MYCN	15	10	25	1034.65
#110	NFE2L2	15	12	27	1313.477
#111	KLF16	15	10	25	844.764
#112	TLX3	15	11	26	1272.443
#113	MTA3	15	14	29	2094.493
#114	NR4A1	15	7	22	712.84
#115	GCM1	15	10	25	1323.259
#116	RERE	15	14	29	953.053
#117	ZNF83	15	8	23	700.569
#118	DLX6	15	14	29	1542.531
#119	NR5A2	15	12	27	1696.16
#120	CREM	15	14	29	1236.874
#121	ESR1	15	11	26	978.223
#122	PITX1	15	15	30	1686.593
#123	MGA	15	10	25	970.034
#124	MYC	15	9	24	1041.836
#125	E2F2	15	14	29	834.373
#126	ZEB2	15	12	27	1201.005
#127	IRF4	15	12	27	1081.12
#128	FOXO3	15	11	26	1202.811
#129	GATA4	15	9	24	903.846
#130	FOXM1	15	3	18	75.914
#131	KLF3	15	8	23	626.685
#132	SP1	15	6	21	294.467
#133	SMAD5	15	11	26	1095.02
#134	MYNN	15	13	28	1439.319
#135	ZFP90	15	9	24	891.155
#136	ZFP36L1	15	16	31	1500.646
#137	ZNF93	14	7	21	610.451
#138	ARID4A	14	14	28	1198.01
#139	ZNF45	14	10	24	1382.359
#140	GTF2H3	14	12	26	1546.477
#141	POU2F3	14	14	28	1143.99
#142	LMO4	14	13	27	1550.662
#143	ISL2	14	12	26	1207.689
#144	PBX3	14	13	27	865.079
#145	BHLHE40	14	16	30	1566.588
#146	CREB1	14	15	29	1356.665
#147	MLXIPL	14	12	26	1199.242
#148	ETS1	14	18	32	1716.406
#149	FOSB	14	7	21	595.48
#150	NCOR1	14	11	25	1077.811
#151	HNF4G	14	16	30	1436.869
#152	BATF	14	10	24	897.03
#153	SIX2	14	12	26	1246.049
#154	AFF4	14	9	23	661.262
#155	BARX1	14	10	24	971.513
#156	LMX1A	14	12	26	1308.921
#157	GAS7	13	15	28	1397.915
#158	RUNX2	13	15	28	1526.193
#159	FOSL2	13	11	24	1249.295
#160	ZNF81	13	14	27	1269.187
#161	FOXP1	13	13	26	1675.028
#162	NFATC2	13	10	23	736.562
#163	STRN3	13	12	25	1638.706
#164	IRF5	13	13	26	1167.175
#165	SMAD1	13	17	30	1576.835
#166	OTX2	13	15	28	1654.769
#167	GSC2	13	9	22	802.77
#168	ESR2	13	15	28	1840.949
#169	SMAD6	13	9	22	1559.799
#170	ZNF169	13	14	27	1330.891
#171	NFIX	13	11	24	866.471
#172	GLI3	13	11	24	1093.763
#173	NPAS2	13	11	24	1219.935
#174	NFE2L3	13	13	26	1222.161
#175	HIRA	13	10	23	1308.288
#176	SPIC	13	14	27	816.556
#177	SUPT6H	13	13	26	1327.151
#178	HES5	13	5	18	756.927
#179	TBX19	13	12	25	1296.423
#180	ESRRG	13	18	31	1814.279
#181	TBX22	13	12	25	1375.512
#182	POU3F1	13	15	28	1669.179
#183	PHF1	13	14	27	1218.738
#184	CSDA	13	17	30	1361.61
#185	POU3F2	13	17	30	1676.311
#186	TADA2A	13	12	25	1385.173
#187	KLF5	12	8	20	967.799
#188	ZBTB38	12	8	20	723.336
#189	CREB3L3	12	12	24	1026.005
#190	ZNF117	12	15	27	1338.413
#191	NKX6-2	12	12	24	566.596
#192	ZSCAN4	12	12	24	1340.667
#193	SATB1	12	13	25	1144.63
#194	MAFG	12	11	23	683.161
#195	SNAPC5	12	12	24	837.623
#196	ZNF500	12	11	23	1100.459
#197	TSC22D3	12	10	22	1463.171
#198	PAX6	12	14	26	1005.27
#199	JUN	12	7	19	433.484
#200	HNF4A	12	16	28	1257.682
#201	MSRB2	12	12	24	978.554
#202	ZNF434	12	11	23	894.769
#203	NR4A2	12	12	24	945.091
#204	TRIM22	12	18	30	1740.574
#205	HOXA7	12	14	26	1099.902
#206	NFE2	12	12	24	1482.06
#207	SREBF1	12	14	26	867.957
#208	FEV	12	9	21	709.302
#209	ZNF219	12	14	26	1540.26
#210	ONECUT2	12	13	25	1299.485
#211	TEAD1	12	11	23	931.592
#212	GLIS2	12	11	23	932.098
#213	MZF1	12	11	23	661.192
#214	FOXO1	12	12	24	1117.806
#215	CUX1	12	10	22	503.974
#216	KLF9	12	13	25	1303.851
#217	CRX	12	11	23	1335.757
#218	TSC22D2	12	13	25	1083.259
#219	RARB	12	12	24	1040.139
#220	SP3	12	15	27	1473.859
#221	ZNF18	11	14	25	1429.261
#222	IRX1	11	13	24	916.025
#223	ZNF19	11	11	22	1261.562
#224	ZNF85	11	13	24	1155.588
#225	PLAG1	11	13	24	1006.138
#226	SCRT1	11	10	21	806.666
#227	BTG2	11	8	19	946.623
#228	ELF5	11	17	28	1498.659
#229	PURB	11	9	20	594.142
#230	SOX6	11	11	22	877.946
#231	T	11	9	20	854.037
#232	ZSCAN12	11	10	21	1536.078
#233	MEF2D	11	12	23	1405.033
#234	HOXD1	11	13	24	1505.595
#235	FOXC1	11	11	22	581.346
#236	ALS2CR8	11	10	21	843.52
#237	FOXC2	11	14	25	1419.23
#238	SIX1	11	17	28	953.868
#239	BUD31	11	11	22	1009.814
#240	ZNF92	11	7	18	726.932
#241	GATAD2B	11	10	21	734.725
#242	ELF3	11	14	25	1287.746
#243	RORB	11	18	29	1372.382
#244	SOX1	11	14	25	1203.698
#245	PLSCR1	11	13	24	1155.988
#246	ZNF256	11	15	26	1582.362
#247	KLF6	11	10	21	617.999
#248	HSF5	11	11	22	1501.915
#249	ZFPM2	11	13	24	1085.792
#250	TFAP2A	11	10	21	611.865
#251	NR2F2	11	13	24	1115.522
#252	FUBP1	11	10	21	679.346
#253	AHR	11	16	27	1416.936
#254	MNX1	11	16	27	1200.462
#255	EPAS1	11	16	27	1588.1
#256	KLF2	11	9	20	983.498
#257	ZSCAN18	11	15	26	858.88
#258	TCF4	11	9	20	909.379
#259	LHX1	11	13	24	811.049
#260	TCFL5	10	14	24	996.348
#261	HOXB8	10	13	23	1945.128
#262	PGR	10	15	25	926.004
#263	ETV5	10	14	24	1321.245
#264	SLC26A3	10	12	22	788.273
#265	L3MBTL4	10	14	24	1171.587
#266	SMAD4	10	12	22	936.957
#267	SOX7	10	12	22	963.66
#268	ATF6B	10	16	26	1144.457
#269	HOXA4	10	7	17	455.381
#270	SPIB	10	10	20	458.804
#271	TEAD3	10	11	21	1137.728
#272	RCOR1	10	13	23	1192.479
#273	PKNOX1	10	16	26	1102.793
#274	HMGB2	10	15	25	1007.222
#275	NPAS1	10	15	25	1442.638
#276	CUX2	10	14	24	1152.65
#277	HOXD3	10	12	22	1761.952
#278	PEG3	10	10	20	1002.754
#279	HHEX	10	13	23	1074.266
#280	NR2F6	10	14	24	1647.54
#281	TBX20	10	14	24	1489.15
#282	LHX2	10	14	24	1046.203
#283	FOXP3	10	19	29	1595.151
#284	RCOR2	10	12	22	946.38
#285	BCL6	10	12	22	1260.744
#286	RUNX1	10	15	25	933.846
#287	ZNF131	10	12	22	1069.851
#288	ZNF157	10	10	20	836.596
#289	TFAP2B	10	10	20	758.205
#290	TBX3	10	13	23	1236.121
#291	TBX21	10	13	23	1073.899
#292	TADA3	10	10	20	785.571
#293	PAX3	10	15	25	1487.21
#294	FOXK2	10	13	23	1138.513
#295	CEBPD	10	9	19	757.938
#296	ZSCAN23	10	11	21	538.03
#297	MAF	10	13	23	994.434
#298	GATA2	10	17	27	1161.242
#299	NANOGNB	10	13	23	787.256
#300	TGIF1	10	14	24	1002.307
#301	ETV1	9	19	28	1097.848
#302	SOX4	9	13	22	908.974
#303	LEF1	9	14	23	1478.61
#304	HOXA10	9	7	16	449.762
#305	GATA3	9	11	20	764.188
#306	STAT1	9	16	25	1194.9
#307	RORA	9	15	24	1119.86
#308	CSRNP3	9	11	20	1004.579
#309	SIX4	9	20	29	1591.066
#310	CREBZF	9	14	23	1149.768
#311	TCF12	9	16	25	1067.545
#312	RUNX1T1	9	11	20	823.132
#313	HOXB9	9	8	17	470.524
#314	ZNF287	9	9	18	592.059
#315	ZNF277	9	9	18	914.536
#316	ZNF268	9	7	16	574.817
#317	ETS2	9	17	26	1194.275
#318	HOXB7	9	11	20	971.723
#319	BCL11B	9	14	23	1046.68
#320	LMX1B	9	12	21	935.856
#321	OTX1	9	10	19	644.546
#322	HEY1	9	14	23	756.178
#323	TEAD2	9	12	21	912.084
#324	VSX1	9	11	20	909.244
#325	POU3F4	9	14	23	1195.828
#326	RARA	9	12	21	664.789
#327	HOXB6	9	13	22	1008.727
#328	TCF7L1	9	14	23	1034.331
#329	PHOX2B	9	11	20	691.03
#330	FOXH1	9	14	23	1132.032
#331	RXRG	9	12	21	727.864
#332	ERF	9	10	19	586.74
#333	ZIC3	9	12	21	933.084
#334	SMAD3	9	14	23	1252.901
#335	POU6F1	9	11	20	768.829
#336	TEF	9	10	19	641.74
#337	NANOG	9	7	16	561.437
#338	GLI2	9	12	21	884.26
#339	ZFHX4	9	16	25	1162.205
#340	SOX11	8	10	18	785.46
#341	EGR1	8	7	15	270.532
#342	PROX1	8	17	25	898.608
#343	THRA	8	9	17	726.182
#344	ZSCAN2	8	13	21	834.947
#345	HNRNPAB	8	11	19	747.316
#346	NPAT	8	14	22	1163.91
#347	LASS6	8	8	16	605.289
#348	ETV6	8	11	19	848.97
#349	ZNF24	8	9	17	425.254
#350	ESRRB	8	9	17	502.007
#351	ZFHX2	8	15	23	823.59
#352	NR4A3	8	15	23	1016.928
#353	ETV7	8	14	22	610.591
#354	MAFB	8	12	20	540.269
#355	ARNT2	8	17	25	1033.209
#356	LZTS1	8	14	22	1279.278
#357	ZNF449	8	9	17	592.271
#358	ZNF483	8	13	21	930.465
#359	RB1	8	10	18	702.983
#360	EHF	8	12	20	835.009
#361	NR1H4	8	13	21	901.637
#362	PAX8	8	12	20	668.291
#363	BCL3	8	12	20	752.878
#364	HOXA2	8	15	23	780.373
#365	GATA6	8	13	21	958.946
#366	FOXK1	8	13	21	792.957
#367	ELF4	8	12	20	632.493
#368	TRERF1	8	13	21	1034.691
#369	NKX3-2	8	7	15	566.063
#370	ATF3	8	13	21	811.259
#371	POU6F2	8	16	24	767.662
#372	HOXD13	8	9	17	652.213
#373	MTA2	8	14	22	973.091
#374	PRDM2	8	11	19	722.219
#375	GLIS3	8	14	22	819.876
#376	MEOX2	8	11	19	860.972
#377	GSX1	8	13	21	569.909
#378	ZNF446	8	11	19	610.186
#379	SOX21	8	14	22	577.771
#380	ATOH1	8	14	22	526.034
#381	ZNF496	8	12	20	792.915
#382	ZIC5	8	10	18	779.98
#383	MEIS2	8	14	22	932.488
#384	REST	7	11	18	775.544
#385	HIC1	7	6	13	373.3
#386	ATF2	7	9	16	328.422
#387	ZFP36L2	7	18	25	734.262
#388	FOXP2	7	14	21	788.493
#389	ZSCAN10	7	13	20	535.006
#390	TSHZ2	7	12	19	887.018
#391	WT1	7	15	22	1015.889
#392	HESX1	7	10	17	400.51
#393	HMGA1	7	13	20	662.128
#394	MAFF	7	17	24	1047.181
#395	DLX1	7	12	19	696.989
#396	EGR2	7	7	14	534.622
#397	HOXD9	7	12	19	914.137
#398	SEBOX	7	11	18	954.596
#399	WNT5A	7	14	21	669.366
#400	NRL	7	10	17	646.688
#401	KLF4	7	23	30	1371.12
#402	LHX9	7	16	23	892.064
#403	ZNF238	7	12	19	560.027
#404	ZNF397	7	16	23	574.941
#405	STAT5B	7	11	18	433.452
#406	HMGA2	7	16	23	807.835
#407	SOX2	7	14	21	620.898
#408	IRX5	7	12	19	892.924
#409	ZNF438	7	11	18	666.618
#410	HOXC13	7	14	21	546.027
#411	BNC1	7	13	20	725.236
#412	SLC2A4RG	7	14	21	510.828
#413	PITX2	7	11	18	536.381
#414	MYT1	7	16	23	723.33
#415	TSC22D1	6	10	16	361.43
#416	NFYC	6	10	16	490.792
#417	NEUROD1	6	13	19	581.493
#418	ZNF639	6	10	16	428.111
#419	ZNF71	6	13	19	519.399
#420	PCGF2	6	16	22	678.752
#421	BLZF1	6	12	18	809.429
#422	ELK1	6	10	16	392.222
#423	HOXC5	6	12	18	410.592
#424	ERG	6	15	21	452.558
#425	SP140	6	8	14	366.092
#426	LHX8	6	18	24	781.962
#427	MECOM	6	16	22	594.03
#428	TRPS1	6	11	17	542.871
#429	KLF12	6	12	18	554.296
#430	FOXA1	6	12	18	406.479
#431	ARNTL2	6	12	18	558.84
#432	ZNF80	6	10	16	511.783
#433	ZNF132	6	16	22	855.292
#434	RAX2	6	12	18	532.532
#435	HOPX	6	13	19	766.153
#436	MESP1	6	7	13	384.48
#437	SCML1	6	15	21	655.617
#438	MKX	6	14	20	672.437
#439	HIF1A	6	15	21	737.893
#440	SIM1	6	20	26	1310.034
#441	ZNF167	6	18	24	1219.738
#442	POU2F1	6	13	19	1314.108
#443	ZNF75D	6	10	16	279.677
#444	NFAT5	5	7	12	383.992
#445	TWIST1	5	15	20	702.726
#446	FOXN4	5	11	16	279.226
#447	RCAN1	5	15	20	798.971
#448	THRB	5	14	19	940.763
#449	BATF3	5	13	18	680.334
#450	IRF6	5	12	17	601.227
#451	NFIA	5	17	22	844.662
#452	FOXD3	5	11	16	327.424
#453	TFEC	5	13	18	539.739
#454	EBF1	5	13	18	832.536
#455	ZNF154	5	14	19	689.519
#456	ZNF91	5	17	22	727.066
#457	FOXA2	5	10	15	532.906
#458	TP63	5	13	18	527.994
#459	MNT	5	14	19	375.051
#460	HLF	5	12	17	420.648
#461	FLI1	5	9	14	311.865
#462	DMRT2	5	19	24	682.222
#463	IRX3	5	12	17	1189.202
#464	ZFP42	5	9	14	377.019
#465	NFIC	5	13	18	473.48
#466	HES1	5	15	20	572.61
#467	HOXA13	5	16	21	504.762
#468	ZSCAN20	5	10	15	675.857
#469	NR2F1	5	18	23	578.485
#470	ANKRD30A	5	12	17	393.57
#471	TCF7L2	5	10	15	580.693
#472	HIF3A	5	17	22	563.504
#473	IKZF4	4	10	14	533.161
#474	MYT1L	4	15	19	463.708
#475	HEY2	4	14	18	256.598
#476	ZNF207	4	17	21	341.985
#477	ISL1	4	17	21	466.285
#478	SCAND2	4	11	15	407.31
#479	FOXB1	4	10	14	386.248
#480	NR5A1	4	17	21	552.094
#481	ARX	4	15	19	694.791
#482	CTBP1	4	14	18	569.435
#483	TP73	4	17	21	636.111
#484	SOX18	4	11	15	438.04
#485	ESX1	4	14	18	374.297
#486	PTH	4	17	21	553.538
#487	CREB5	3	18	21	548.115
#488	NFIB	3	14	17	369.219
#489	FOXE1	3	11	14	262.173
#490	KLF17	3	14	17	390.029
#491	REL	3	14	17	275.383
#492	DMBX1	3	12	15	345.6
#493	HOXD11	3	12	15	269.575
#494	TLX2	3	13	16	349.371
#495	ZNF396	3	16	19	363.124
#496	FOXA3	3	13	16	402.105
#497	SALL1	2	13	15	160.728
#498	SIX3	2	16	18	348.168
#499	ELK4	2	9	11	173.367
#500	NR1H3	2	12	14	232.957