Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	E2F4	110	0	110	0
#2	CNBP	75	2	77	493.76
#3	MMP14	65	2	67	550.485
#4	ZNF444	63	2	65	64.683
#5	HSF4	61	6	67	8911.378
#6	TAF7	61	4	65	4495.569
#7	ZNF236	59	4	63	108.821
#8	USF2	59	5	64	4102.447
#9	REST	57	5	62	1075.517
#10	FOXJ2	57	5	62	292.796
#11	HOXD1	56	7	63	418.571
#12	VDR	56	3	59	580.343
#13	SNAPC4	56	8	64	988.421
#14	RARG	56	4	60	100.569
#15	LHX3	55	8	63	218.209
#16	HMX1	53	2	55	299.73
#17	NR2C1	48	8	56	481.471
#18	TCF15	47	2	49	26.201
#19	PAX8	46	4	50	48.37
#20	ELK1	46	2	48	19.767
#21	ZNF446	45	12	57	3070.943
#22	PKNOX2	44	10	54	1115.962
#23	AFF1	44	14	58	5734.258
#24	HOXC11	44	6	50	809.999
#25	POU2F2	44	3	47	135.175
#26	MLXIPL	44	2	46	1898.255
#27	HNRNPAB	43	13	56	11092.649
#28	EDF1	41	9	50	1047.427
#29	ZNF238	41	9	50	792.664
#30	MBD1	41	7	48	2807.23
#31	SLC30A9	40	5	45	333.008
#32	SP4	38	8	46	294.258
#33	HNRNPK	38	5	43	86.107
#34	PURA	37	8	45	784.927
#35	MYOG	37	6	43	971.803
#36	HMGB2	36	5	41	2226.742
#37	NFATC1	35	4	39	594.045
#38	TCF7	35	11	46	417.95
#39	PHF1	34	4	38	1138.865
#40	NFE2L2	34	9	43	659.877
#41	IRF2	34	14	48	6932.511
#42	NR6A1	34	8	42	906.837
#43	TCF12	34	8	42	438.189
#44	HNF1B	34	13	47	431.825
#45	GATA2	34	10	44	3871.342
#46	PRRX2	33	15	48	19975.655
#47	SMAD6	33	6	39	107.502
#48	RBPJ	32	9	41	928.747
#49	NFKB2	32	7	39	1788.398
#50	ZNF207	32	8	40	1228.718
#51	EVX1	31	4	35	36.449
#52	YBX1	31	5	36	142.599
#53	PRRX1	30	13	43	6463.065
#54	CSDA	30	7	37	135.341
#55	NR2F2	30	11	41	1593.926
#56	SCAND1	30	9	39	198.625
#57	HEYL	30	8	38	946.388
#58	GBX1	30	12	42	3352.474
#59	LASS6	29	11	40	11981.84
#60	MEIS3P1	29	9	38	314.731
#61	TCF3	29	3	32	49.315
#62	IKZF1	28	9	37	1222.201
#63	SOX4	28	11	39	3257.064
#64	RARB	28	11	39	343.699
#65	CREBL2	28	11	39	673.886
#66	KDM5B	27	12	39	14759.46
#67	CBFB	27	10	37	2831.835
#68	PCGF2	27	6	33	2933.197
#69	FOXJ3	27	17	44	28282.474
#70	ETV1	27	18	45	1437.155
#71	ADNP	26	10	36	527.549
#72	NFE2L1	26	10	36	334.134
#73	HNF4A	25	13	38	4712.04
#74	HOXA11	25	11	36	828.998
#75	NPAT	25	11	36	859.502
#76	PAX5	25	11	36	2039.651
#77	SOX15	25	8	33	396.387
#78	RUNX2	24	14	38	4019.912
#79	KLF5	24	9	33	582.242
#80	RFX5	24	12	36	613.94
#81	ZKSCAN3	23	11	34	122.991
#82	CTCF	23	17	40	4180.035
#83	NR3C1	23	11	34	946.139
#84	NR4A2	23	3	26	209.725
#85	NFIB	23	12	35	1102.687
#86	MLLT10	22	19	41	19917.337
#87	ATF6B	22	8	30	5072.204
#88	STAT3	22	13	35	392.802
#89	HIF3A	22	7	29	521.135
#90	TGIF1	22	10	32	1159.994
#91	SOX2	21	13	34	753.731
#92	HDAC2	21	12	33	432.408
#93	TSC22D4	21	6	27	250.115
#94	ELK3	21	12	33	1337.741
#95	KLF7	21	12	33	1243.118
#96	SNAPC2	20	9	29	415.61
#97	HMG20B	20	9	29	1270.206
#98	BTAF1	20	12	32	1724.814
#99	TBX2	20	10	30	1808.171
#100	SALL2	20	11	31	1487.888
#101	CREBBP	20	11	31	912.195
#102	DLX2	19	10	29	1760.792
#103	PLSCR1	19	13	32	7726.816
#104	CNOT8	19	14	33	462.049
#105	MZF1	19	9	28	1131.388
#106	HDAC1	19	16	35	966.258
#107	TCF20	19	12	31	1409.852
#108	ZNF287	19	11	30	826.738
#109	EGR4	18	8	26	401.122
#110	SMAD4	18	15	33	1195.606
#111	HSF2	18	12	30	1281.54
#112	ZSCAN18	18	5	23	146.107
#113	BHLHE40	18	6	24	2834.562
#114	MYBL2	18	11	29	2026.794
#115	STAT4	18	9	27	579.211
#116	PHOX2B	18	12	30	1071.142
#117	RCOR1	17	16	33	6230.027
#118	TBX5	17	15	32	3281.055
#119	GATAD1	17	15	32	9407.237
#120	GLI3	17	12	29	7368.029
#121	MECOM	17	15	32	1945.185
#122	RCAN1	17	10	27	236.074
#123	SPIB	17	12	29	801.003
#124	SMAD2	17	9	26	382.696
#125	MEF2A	17	10	27	1774.032
#126	SOX10	16	11	27	481.271
#127	MEF2D	16	11	27	822.144
#128	TCFL5	16	8	24	802.618
#129	POU5F1B	16	9	25	131.199
#130	CITED2	16	13	29	1947.696
#131	TFAP4	16	14	30	468.433
#132	FOXP3	15	14	29	1689.175
#133	FOXC2	15	13	28	56178.354
#134	FEV	15	10	25	421.145
#135	TRIM22	15	9	24	134.083
#136	ATF3	15	3	18	39.263
#137	ATF2	15	9	24	238.622
#138	ENO1	15	12	27	1660.299
#139	PBX1	15	13	28	11006.01
#140	RXRB	15	15	30	937.27
#141	MSC	15	7	22	47.981
#142	STAT5A	15	14	29	2053.666
#143	ZBTB17	15	10	25	1270.53
#144	NFIL3	14	8	22	2740.866
#145	BRD8	14	15	29	2207.462
#146	RB1	14	11	25	971.948
#147	LZTS1	14	14	28	762.69
#148	TFDP1	14	8	22	72.025
#149	SUPT6H	14	10	24	235.042
#150	RUNX1T1	14	11	25	3516.584
#151	FOXN3	14	17	31	2252.524
#152	ZFP36L2	14	12	26	1526.541
#153	EPAS1	14	15	29	1765.386
#154	KLF4	14	12	26	1461.018
#155	ZBTB48	14	8	22	9917.796
#156	CEBPB	13	12	25	312.602
#157	TBX19	13	15	28	282.439
#158	IRF4	13	13	26	1730.235
#159	HMGB1	13	9	22	4264.958
#160	HMG20A	13	16	29	52826.001
#161	ETV4	13	15	28	446.493
#162	POU4F2	13	12	25	14242.758
#163	TFE3	13	16	29	3737.732
#164	PAX4	13	13	26	3026.893
#165	CNOT7	13	13	26	330.467
#166	SIX5	13	10	23	146.742
#167	NCOR1	13	16	29	2116.584
#168	FOXF2	13	11	24	138.003
#169	RARA	13	16	29	389.351
#170	MYT1	13	14	27	221.088
#171	RERE	13	17	30	1405.502
#172	HNF1A	13	14	27	2065.643
#173	TAF5L	12	12	24	11803.666
#174	PITX3	12	14	26	1861.511
#175	TFEB	12	12	24	5200.904
#176	ZKSCAN1	12	14	26	947.367
#177	MSRB2	12	14	26	3342.001
#178	TRIM28	12	12	24	1879.836
#179	TBX4	12	12	24	4584.823
#180	HIC1	12	11	23	1712.686
#181	ESRRA	12	8	20	2209.973
#182	UBP1	12	15	27	593.735
#183	SP3	12	7	19	1255.644
#184	BUD31	12	9	21	2618.054
#185	LEF1	12	10	22	463.506
#186	YY1	12	9	21	283.747
#187	IRF3	11	11	22	1784.776
#188	HOXC10	11	13	24	692.872
#189	STRN3	11	12	23	10247.505
#190	HOXD11	11	13	24	220.925
#191	ZFP36L1	11	13	24	8848.566
#192	TCF4	11	15	26	24657.081
#193	IKZF4	10	18	28	599.066
#194	JUN	10	8	18	381.586
#195	BTG2	10	5	15	322.505
#196	FOXO4	10	13	23	4549.368
#197	SIM2	10	15	25	2992.775
#198	RFXANK	10	10	20	4726.536
#199	NR3C2	10	12	22	1002.425
#200	GATA1	10	16	26	179.947
#201	BARX1	10	15	25	3811.431
#202	RBCK1	10	14	24	762.077
#203	NFATC4	10	13	23	1424.635
#204	NEUROD2	10	15	25	1039.501
#205	ZNF140	10	14	24	45832.073
#206	KLF15	10	21	31	2324.834
#207	PRDM1	10	12	22	743.011
#208	HOXD9	10	11	21	2169.223
#209	NANOG	10	12	22	521.074
#210	ATF7	10	9	19	1163.89
#211	VSX1	10	12	22	69.079
#212	IRF7	9	11	20	2742.966
#213	HOXC5	9	16	25	640.82
#214	GATA3	9	15	24	3815.642
#215	BHLHE41	9	9	18	736.87
#216	FOXA1	9	17	26	14840.157
#217	TAL1	9	18	27	5198.689
#218	MTA1	9	13	22	8229.494
#219	ZNF93	9	17	26	1554.128
#220	ZNF192	9	14	23	396.259
#221	KLF6	9	10	19	6017.281
#222	ETS2	9	11	20	1272.972
#223	ATF1	9	14	23	117.154
#224	MEIS1	9	13	22	252.931
#225	TSC22D1	9	13	22	1217.116
#226	RXRA	9	14	23	1662.535
#227	MLL	9	16	25	1193.034
#228	JUNB	9	9	18	1361.532
#229	ZNF217	9	13	22	249.355
#230	NR2F6	9	16	25	4614.523
#231	TCF25	8	16	24	8499.266
#232	ESRRG	8	9	17	485.648
#233	GTF2H3	8	15	23	2512.571
#234	MEF2C	8	14	22	11956.541
#235	ZBTB38	8	7	15	833.035
#236	MEIS2	8	9	17	460.768
#237	TARDBP	8	12	20	1871.568
#238	FOXH1	8	16	24	826.968
#239	MYOD1	8	15	23	947.056
#240	NR1I2	8	13	21	844.342
#241	BCL3	8	19	27	9294.799
#242	ATF5	8	13	21	8433.678
#243	ZNF134	8	11	19	1028.65
#244	FOXJ1	8	13	21	1942.379
#245	PHOX2A	8	13	21	2734.833
#246	ZNF91	8	9	17	1465.494
#247	HOXA5	8	16	24	1072.316
#248	E4F1	8	15	23	6703.294
#249	HOXC13	8	14	22	924.28
#250	ZGPAT	8	8	16	91.608
#251	ELF2	8	14	22	1053.706
#252	KLF12	7	15	22	422.502
#253	PTTG1	7	17	24	1809.807
#254	LASS2	7	11	18	805.677
#255	ETV7	7	16	23	1067.803
#256	ZNF45	7	16	23	3582.138
#257	SATB2	7	14	21	1911.467
#258	IRF1	7	9	16	424.472
#259	FOXO3	7	11	18	742.211
#260	ETV5	7	14	21	4078.57
#261	JUND	7	16	23	16628.7
#262	PPBPL2	7	13	20	772.709
#263	TAF4	7	11	18	4062.022
#264	FOSB	7	6	13	684.449
#265	ELF1	7	14	21	3286.956
#266	TCF7L2	7	17	24	2167.106
#267	PA2G4	7	17	24	3365.791
#268	HR	7	13	20	334.524
#269	ZHX2	7	7	14	480.971
#270	ZNF167	7	19	26	5011.309
#271	WNT5A	7	14	21	55223.296
#272	ISL1	7	19	26	7345.309
#273	RUNX1	7	13	20	2391.561
#274	HCFC1	7	14	21	2066.717
#275	CRX	7	15	22	245.318
#276	EGR2	7	7	14	183.443
#277	SIX1	7	16	23	2938.616
#278	CCRN4L	7	11	18	339.2
#279	FOXC1	7	17	24	4401.521
#280	PHTF1	7	11	18	63.509
#281	TBX6	6	14	20	4477.863
#282	MNT	6	18	24	2626.39
#283	SATB1	6	15	21	647.486
#284	SPDEF	6	16	22	4996.967
#285	CEBPD	6	18	24	393.029
#286	ZNF24	6	9	15	914.717
#287	NRL	6	15	21	912.905
#288	EMX1	6	16	22	1846.748
#289	DDIT3	6	16	22	6772.163
#290	CREB3L1	6	10	16	885.673
#291	CDX2	6	15	21	159.494
#292	KDM5A	6	8	14	3361.713
#293	NOLC1	6	13	19	764.893
#294	XBP1	6	15	21	169.357
#295	HOXA3	6	15	21	729.171
#296	LHX5	6	12	18	4373.296
#297	HAND2	6	12	18	4295.273
#298	HOXA9	6	17	23	1229.814
#299	HEY1	6	12	18	285.615
#300	TFCP2L1	6	17	23	592.705
#301	TSC22D2	6	16	22	275.621
#302	HMGA1	6	17	23	2725.198
#303	NR2E3	6	14	20	394.738
#304	CTBP1	5	13	18	371.982
#305	SPEN	5	10	15	1210.621
#306	PRDM2	5	20	25	510.31
#307	CREM	5	11	16	309.955
#308	LMX1B	5	18	23	6301.935
#309	HOXD3	5	15	20	2363.206
#310	ZNF219	5	11	16	493.865
#311	ZNF434	5	19	24	5271.005
#312	HIF1A	5	17	22	3283.675
#313	NFATC3	5	14	19	87.549
#314	TP63	5	12	17	8967.876
#315	PITX1	5	9	14	515.561
#316	ALX1	5	15	20	201.419
#317	EGR3	5	12	17	875.782
#318	ETV2	5	15	20	4663.351
#319	THRB	5	11	16	625.953
#320	ECSIT	5	17	22	3065.747
#321	DLX4	5	15	20	265.005
#322	IRF9	5	17	22	5796.495
#323	SOX13	5	15	20	217.09
#324	CREBZF	5	14	19	1131.9
#325	EHF	5	14	19	20021.291
#326	NR4A3	5	20	25	4365.627
#327	NR1H2	5	10	15	255.12
#328	STAT1	5	14	19	390.469
#329	MSL3	5	18	23	6486.441
#330	HCLS1	5	13	18	1364.721
#331	SNAI2	4	14	18	10930.687
#332	IRF8	4	18	22	9339.58
#333	NFAT5	4	11	15	2399.982
#334	ZNF117	4	16	20	870.528
#335	PKNOX1	4	16	20	1758.392
#336	SNAPC5	4	18	22	2761.02
#337	HLF	4	17	21	3692.255
#338	ASCL1	4	11	15	356.67
#339	KLF10	4	12	16	182.546
#340	GAS7	4	16	20	2430.717
#341	ZNF232	4	17	21	2313.104
#342	TFAM	4	13	17	4323.189
#343	RAX	4	18	22	52407.65
#344	ZNF148	4	17	21	3530.454
#345	SPI1	4	21	25	23858.63
#346	DRAP1	4	13	17	246.112
#347	NFX1	4	15	19	1580.702
#348	BCL6	4	15	19	367.938
#349	FOXA2	4	21	25	584.252
#350	PLAG1	4	12	16	1409.347
#351	MAFB	4	19	23	2632.945
#352	HOXB5	4	18	22	344.727
#353	MYCL1	4	14	18	1581.909
#354	HOXB6	4	13	17	952.995
#355	NKX2-8	4	14	18	297.323
#356	NEUROG1	4	13	17	738.733
#357	RORC	4	6	10	182.961
#358	FOXE1	4	17	21	1973.684
#359	LZTR1	4	15	19	469.473
#360	TCEAL1	4	15	19	224.162
#361	NPAS1	4	13	17	6020.562
#362	HOXB1	4	8	12	92.302
#363	LHX1	4	11	15	124.71
#364	ERF	4	4	8	1051.143
#365	CUX1	3	19	22	413.434
#366	ELF5	3	12	15	204.129
#367	HOXD4	3	14	17	259.437
#368	HOXD10	3	13	16	179.911
#369	FBXW7	3	15	18	960.47
#370	EGR1	3	10	13	478.504
#371	TSHZ2	3	18	21	578.915
#372	TP53	3	20	23	985.442
#373	KLF3	3	16	19	5478.409
#374	FOXM1	3	12	15	401.047
#375	MAFG	3	15	18	505.064
#376	RELA	3	13	16	109.215
#377	SRF	3	13	16	5766.004
#378	CIR1	3	15	18	1492.396
#379	PBX2	3	10	13	77.574
#380	ELF3	3	16	19	10441.226
#381	IRX5	3	12	15	469.114
#382	HOXA1	3	12	15	1057.723
#383	LMO4	3	14	17	1999.847
#384	MAFF	3	12	15	8735.832
#385	FOS	3	9	12	596.337
#386	ZIC3	3	20	23	754.922
#387	AEBP1	3	21	24	6576.025
#388	C2orf3	3	14	17	106.645
#389	KLF2	3	13	16	656.277
#390	SOX21	3	15	18	3131.723
#391	TBX10	3	17	20	1005.736
#392	TP73	3	21	24	2182.535
#393	TAF12	3	11	14	1847.896
#394	NOTCH1	3	11	14	687.868
#395	IRF6	3	13	16	249.084
#396	RELB	3	15	18	5640.192
#397	NR0B1	3	16	19	1727.452
#398	ESR1	3	18	21	204.014
#399	NFYC	3	12	15	734.337
#400	CEBPE	3	16	19	482.027
#401	NR5A1	3	13	16	560.683
#402	NR4A1	3	10	13	1998.176
#403	TRIM25	3	10	13	620.356
#404	ZNF215	3	16	19	2952.978
#405	STAT2	3	17	20	704.01
#406	C11orf9	2	16	18	767.175
#407	AHR	2	14	16	144.427
#408	SUPT4H1	2	10	12	694.754
#409	HEY2	2	15	17	3747.302
#410	ZNF131	2	14	16	145.48
#411	GCFC1	2	11	13	54.916
#412	SMAD9	2	19	21	50.288
#413	ARNTL2	2	18	20	137.452
#414	POU6F1	2	14	16	1213.453
#415	ATF6	2	12	14	164.642
#416	ZNF189	2	10	12	111.261
#417	NR1H3	2	11	13	1862.198
#418	ATF4	2	17	19	806.75
#419	NFYB	2	14	16	2223.734
#420	TEAD4	2	17	19	69.421
#421	MGA	2	14	16	165.086
#422	FOSL1	2	8	10	309.226
#423	ZNF83	2	19	21	1296.785
#424	MTA2	2	16	18	1780.049
#425	MTF1	2	17	19	458.353
#426	MYC	2	11	13	356.959
#427	NFIC	2	19	21	2962.68
#428	SCML2	2	10	12	260.496
#429	TLX3	2	13	15	1304.024
#430	TCF7L1	2	20	22	3330.182
#431	SCAND2	2	21	23	71.45
#432	HOXC8	2	19	21	621.519
#433	HOXC4	2	19	21	119.116
#434	HOXB2	2	15	17	1814.348
#435	CREB3L2	2	16	18	69.943
#436	NFE2	2	18	20	8961.995
#437	TSC22D3	2	17	19	1686.933
#438	TADA3	2	12	14	924.619
#439	ARNT	2	15	17	391.908
#440	CBL	2	12	14	98.057
#441	UBN1	2	21	23	79.516
#442	DLX6	2	14	16	49.243
#443	THRA	2	13	15	827.354
#444	FOXG1	2	13	15	5807.402
#445	SMAD1	2	15	17	142.806
#446	SOLH	2	14	16	915.734
#447	ESR2	2	19	21	720.239
#448	ZNF277	1	10	11	14.978
#449	PAX3	1	15	16	432.369
#450	MAX	1	16	17	117.933
#451	E2F1	1	13	14	15.055
#452	ZIC1	1	9	10	168.456
#453	RNF4	1	16	17	142.688
#454	FOXO1	1	16	17	176.085
#455	GRHL2	1	13	14	83.106
#456	HES1	1	15	16	814.706
#457	BACH1	1	9	10	44.927
#458	SREBF2	1	20	21	1520.394
#459	BATF	1	15	16	42.511
#460	HOXA10	1	11	12	132.233
#461	TRIM29	1	16	17	169.941
#462	SOX9	1	17	18	1190.259
#463	ZFHX3	1	17	18	1429.115
#464	ZNF323	1	14	15	141.663
#465	IRF5	1	14	15	10.054
#466	PBX3	1	14	15	183.161
#467	HOPX	1	17	18	645.963
#468	TFCP2	1	16	17	546.032
#469	HOXB3	1	13	14	12.203
#470	BATF3	1	17	18	515.124
#471	PLAGL2	1	13	14	30.609
#472	MNX1	1	12	13	165.031
#473	NFKB1	1	12	13	366.642
#474	FOSL2	1	14	15	1814.185
#475	REL	1	14	15	650.381
#476	ZNF3	1	12	13	110.84
#477	FOXD1	1	15	16	2109.439
#478	ZNF165	1	11	12	21.973
#479	POU3F1	1	22	23	517.923
#480	NKX2-1	1	17	18	287.616
#481	KLF9	1	18	19	1321.353
#482	SIX2	1	12	13	946.909
#483	FUBP1	1	14	15	825.65
#484	ZNF274	1	7	8	7.426
#485	NR1D2	1	11	12	899.688
#486	HIRA	1	12	13	1605.272
#487	HMBOX1	0	16	16	0
#488	RUNX3	0	18	18	0
#489	CREB1	0	11	11	0
#490	NR2F1	0	10	10	0
#491	TRPS1	0	10	10	0
#492	SREBF1	0	18	18	0
#493	LHX6	0	13	13	0
#494	CDKN2A	0	16	16	0
#495	STAT6	0	17	17	0
#496	CTNNB1	0	18	18	0
#497	NKX3-1	0	22	22	0
#498	MYCN	0	16	16	0
#499	E2F3	0	12	12	0
#500	DMTF1	0	13	13	0