Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TFAP4	55	2	57	202.402
#2	KLF5	51	5	56	1460.361
#3	HOXB1	45	2	47	382.676
#4	ZFP36L1	41	1	42	5623.07
#5	TRIM28	40	4	44	741.549
#6	TGIF2	37	9	46	7506.777
#7	SCML2	37	5	42	276.591
#8	HCLS1	36	1	37	41.503
#9	MAFK	36	3	39	167.755
#10	CSDA	36	5	41	227.168
#11	CREB1	34	6	40	5264.582
#12	CEBPB	33	4	37	396.631
#13	AHR	32	5	37	654.507
#14	TFAP2A	32	4	36	262.647
#15	NR2F2	30	2	32	37.776
#16	POU2F1	30	2	32	265.84
#17	MTF1	29	5	34	517.75
#18	E2F3	29	9	38	3160.894
#19	POU6F2	28	6	34	1341.61
#20	HMGB2	28	4	32	616.074
#21	MYCN	28	8	36	722.022
#22	E2F2	27	11	38	2929.818
#23	TAF4	27	2	29	157.161
#24	FLI1	27	2	29	33.278
#25	REL	27	6	33	537.652
#26	FOXM1	27	3	30	1216.813
#27	PLAGL2	26	6	32	950.393
#28	PLSCR1	26	6	32	1177.177
#29	MEF2C	26	6	32	152.917
#30	HMGA1	26	6	32	535.138
#31	ZFHX3	25	6	31	4377.999
#32	NR1H2	25	7	32	1282.272
#33	KLF7	25	1	26	102.685
#34	RUNX3	25	7	32	1084.554
#35	ZSCAN12	25	5	30	2291.477
#36	HMX1	25	8	33	1416.507
#37	CREB3L2	25	7	32	201.417
#38	ZNF167	25	5	30	3342.154
#39	THRB	24	7	31	998.941
#40	BHLHE40	24	9	33	1286.826
#41	PA2G4	23	9	32	2001.75
#42	NPAT	23	8	31	2099.729
#43	HHEX	23	6	29	194.113
#44	MYBL2	23	6	29	956.759
#45	CUX1	22	4	26	254.932
#46	DLX4	22	2	24	152.176
#47	E2F6	22	13	35	2735.613
#48	TBP	22	7	29	1739.562
#49	POU3F4	22	10	32	2391.917
#50	TBX2	22	14	36	3841.996
#51	TP53	22	11	33	3930.358
#52	MXD1	22	1	23	52.567
#53	SMAD4	22	6	28	1075.359
#54	HOXD13	22	10	32	2505.009
#55	ESR1	21	1	22	777.958
#56	GATA3	21	7	28	741.942
#57	SP3	21	9	30	1306.987
#58	NFIC	21	7	28	1353.393
#59	NFYC	21	10	31	923.912
#60	BCL3	21	4	25	1327.985
#61	KLF4	21	10	31	1217.925
#62	KDM5A	21	12	33	2037.679
#63	ADNP2	21	6	27	1184.83
#64	ELF4	21	9	30	1490.844
#65	ZBTB25	21	8	29	3238.526
#66	ETV6	21	5	26	1221.723
#67	LEF1	20	6	26	3719.731
#68	LZTR1	20	4	24	450.552
#69	DBP	20	5	25	952.011
#70	MSX2	20	11	31	3277.257
#71	SMAD1	20	6	26	357.004
#72	JUN	19	10	29	914.401
#73	AFF1	19	7	26	1233.133
#74	PPARD	19	13	32	5286.254
#75	FOXD1	19	5	24	175.661
#76	TFEC	19	4	23	383.113
#77	PITX3	19	13	32	4013.484
#78	PAX5	19	10	29	755.854
#79	RXRB	19	14	33	3931.602
#80	MYT1	19	7	26	1085.149
#81	HOXB5	19	11	30	3052.081
#82	RERE	19	4	23	383.189
#83	NR2C1	19	14	33	2343.253
#84	ZNF132	19	16	35	1540.432
#85	HES1	18	8	26	1113.971
#86	CDX2	18	13	31	3252.149
#87	CEBPD	18	3	21	84.75
#88	UBN1	18	9	27	458.042
#89	SOX4	18	8	26	731.973
#90	POU1F1	18	4	22	931.737
#91	FOXI1	18	12	30	1354.033
#92	PPARA	18	5	23	1007.175
#93	NR1H4	18	4	22	113.346
#94	TGIF1	18	8	26	1663.192
#95	ZNF24	18	8	26	1029.068
#96	NFX1	18	11	29	3065.876
#97	CREM	18	6	24	2330.128
#98	NFE2L2	18	10	28	3097.752
#99	ELF2	18	10	28	1848.889
#100	PHOX2B	18	9	27	2793.946
#101	CEBPE	18	6	24	861.18
#102	IKZF1	17	9	26	1387.202
#103	ATF2	17	6	23	1052.266
#104	ELF1	17	4	21	82.665
#105	FOXC1	17	12	29	2077.453
#106	GATA1	17	12	29	3742.116
#107	ZHX2	17	11	28	2263.154
#108	ZNF133	17	10	27	1909.654
#109	MZF1	17	14	31	2647.593
#110	TFAP2B	16	11	27	1861.086
#111	SIM1	16	8	24	712.326
#112	PCGF2	16	18	34	1912.03
#113	FOXO3	16	7	23	464.893
#114	TEAD4	16	11	27	512.994
#115	SATB2	16	13	29	3686.651
#116	FOXN3	16	15	31	1916.95
#117	MAF	16	5	21	50.983
#118	RELA	16	13	29	2564.818
#119	TFAP2C	16	6	22	392.708
#120	ZNF135	16	13	29	1155.766
#121	SPDEF	16	6	22	543.115
#122	RBPJ	16	7	23	840.454
#123	MITF	15	9	24	262.331
#124	HDAC1	15	10	25	2712.369
#125	PHF1	15	9	24	832.83
#126	FUBP1	15	8	23	874.143
#127	THRA	15	12	27	1308.865
#128	SREBF1	15	9	24	3178.208
#129	ZNF91	15	7	22	853.586
#130	NR3C2	15	9	24	1406.906
#131	ZKSCAN4	15	14	29	1682.428
#132	ARNT	15	13	28	1428.404
#133	HOXA11	15	6	21	2547.629
#134	ZNF238	15	16	31	3776.046
#135	HNRNPAB	15	6	21	1197.028
#136	SPEN	15	9	24	2699.852
#137	MEOX1	15	12	27	906.452
#138	ETV2	15	16	31	2333.875
#139	NR2E3	15	6	21	513.775
#140	HSF2	14	6	20	2620.759
#141	NFATC4	14	16	30	2117.99
#142	HNF1A	14	9	23	3503.409
#143	CBFA2T2	14	19	33	1586.379
#144	SNAI2	14	8	22	2662.059
#145	TCF12	14	11	25	967.775
#146	MLLT10	14	5	19	391.925
#147	KLF6	14	10	24	1741.124
#148	AEBP1	14	11	25	907.132
#149	GATAD1	14	9	23	269.581
#150	MYT1L	14	8	22	1755.997
#151	ZNF3	14	8	22	2705.923
#152	SIX6	14	12	26	6041.047
#153	ESRRA	14	7	21	2239.216
#154	RXRG	14	20	34	2615.171
#155	HDAC2	14	9	23	1375.232
#156	MLL	14	11	25	542.935
#157	HNF1B	14	8	22	1600.052
#158	KLF9	14	10	24	1357.533
#159	TCF25	14	4	18	284.418
#160	PTTG1	14	3	17	44.643
#161	SMAD5	13	15	28	3512.32
#162	SUPT6H	13	16	29	3891.302
#163	GLI3	13	10	23	923.197
#164	ZNF217	13	13	26	1647.75
#165	NR3C1	13	15	28	3171.895
#166	GATA2	13	12	25	480.693
#167	KLF1	13	8	21	886.134
#168	GABPB1	13	10	23	877.725
#169	HOXC4	13	13	26	883.135
#170	T	13	12	25	3489.136
#171	ELK1	13	13	26	1270.924
#172	NEUROD2	13	9	22	1808.038
#173	TLX1	13	12	25	1156.3
#174	FOXG1	13	9	22	1512.33
#175	PRDM1	13	5	18	496.279
#176	TBR1	13	13	26	3896.469
#177	STAT6	13	9	22	474.412
#178	LHX2	13	13	26	2420.506
#179	TRIM25	13	17	30	3346.076
#180	ZNF193	13	3	16	334.061
#181	HIC1	13	14	27	4719.59
#182	VDR	13	12	25	2072.517
#183	NFYB	13	6	19	2252.566
#184	ELK3	13	10	23	1008.366
#185	ATF6	13	17	30	3319.438
#186	NPAS2	12	16	28	2338.294
#187	ONECUT1	12	6	18	279.935
#188	JUNB	12	5	17	76.736
#189	VAV1	12	4	16	477.388
#190	ALX1	12	11	23	4695.535
#191	SUPT4H1	12	10	22	2468.489
#192	TLX2	12	14	26	1067.686
#193	ZFP36L2	12	19	31	2753.569
#194	CREBZF	12	11	23	1383.212
#195	SOX2	12	14	26	2143.533
#196	ZNF175	12	10	22	1932.324
#197	POU2F3	12	16	28	3163.67
#198	ZNF263	12	13	25	1024.12
#199	CIR1	12	9	21	1431.981
#200	E2F1	12	6	18	1387.123
#201	TAF10	12	7	19	995.747
#202	FOXN2	12	11	23	954.596
#203	PFDN1	12	13	25	1916.859
#204	NR2C2	12	11	23	767.969
#205	TSC22D3	12	9	21	913.792
#206	ETS2	11	16	27	1340.687
#207	TAF6	11	12	23	1264.565
#208	CREBL2	11	12	23	1152.285
#209	MYF6	11	12	23	973.075
#210	PAX3	11	13	24	2194.241
#211	PRRX1	11	10	21	833.652
#212	HMG20B	11	10	21	867.488
#213	ALX3	11	10	21	3123.843
#214	RCAN1	11	10	21	2333.883
#215	SOX10	11	10	21	3142.363
#216	FOXA2	11	15	26	3050.975
#217	ZNF117	11	6	17	333.369
#218	C11orf9	11	9	20	764.35
#219	STAT5A	11	13	24	1275.315
#220	TAF5	11	9	20	321.113
#221	ARNT2	11	11	22	1043.891
#222	TBX1	11	9	20	815.265
#223	ZEB2	11	17	28	904.989
#224	HNF4G	11	7	18	779.864
#225	IRF1	10	11	21	1078.816
#226	TRIM22	10	9	19	1665.569
#227	MAX	10	12	22	1003.296
#228	NR2F6	10	19	29	1731.913
#229	EGR2	10	10	20	491.54
#230	NEUROD1	10	7	17	2160.858
#231	HOXD3	10	16	26	1204.247
#232	FOSL1	10	11	21	2274.569
#233	TEAD3	10	19	29	1507.577
#234	BATF	10	7	17	236.602
#235	SOX21	10	13	23	1697.44
#236	POU3F1	10	18	28	2494.833
#237	SOLH	10	13	23	498.853
#238	ELF3	10	9	19	1136.127
#239	TAF4B	10	10	20	954.192
#240	ATF5	10	11	21	1526.588
#241	GLI2	10	6	16	1699.775
#242	STAT3	10	11	21	782.584
#243	FOXO1	10	12	22	945.442
#244	HOXA10	10	8	18	1086.496
#245	TCF21	10	16	26	2162.648
#246	NFYA	10	12	22	579.594
#247	TFAM	10	9	19	521.218
#248	MSC	10	12	22	1142.24
#249	ZFP37	10	12	22	636.651
#250	ATF4	10	15	25	3231.705
#251	HSF1	10	12	22	1646.994
#252	ZNF75D	9	11	20	1586.327
#253	PROX1	9	12	21	937.492
#254	SOX13	9	10	19	460.554
#255	EGR3	9	9	18	525.676
#256	TWIST1	9	17	26	875.305
#257	CSRNP2	9	10	19	886.423
#258	HOXD8	9	15	24	854.111
#259	STAT5B	9	11	20	1415.305
#260	ZNF202	9	7	16	1719.963
#261	RFX3	9	18	27	4134.276
#262	IRF4	9	5	14	275.673
#263	NR4A1	9	4	13	446.911
#264	SMAD2	9	14	23	991.73
#265	ELF5	9	6	15	630.573
#266	GAS7	9	13	22	553.157
#267	MEIS1	9	13	22	1022.714
#268	RARA	9	14	23	1369.746
#269	NFIB	9	11	20	2632.852
#270	TSC22D2	9	12	21	1082.303
#271	ESRRB	9	12	21	1069.555
#272	EPAS1	9	12	21	2325.105
#273	NFE2	9	10	19	878.555
#274	HOPX	9	9	18	271.706
#275	PRDM2	9	10	19	2618.324
#276	POU3F2	9	15	24	2340.901
#277	TCFL5	9	18	27	1775.772
#278	LASS6	9	14	23	1107.638
#279	ATF1	9	14	23	2447.085
#280	NR4A3	9	7	16	1013.661
#281	ISL1	9	11	20	2023.654
#282	SALL2	8	15	23	1983.8
#283	IRF5	8	13	21	1168.977
#284	ESRRG	8	17	25	3742.714
#285	ZNF500	8	18	26	3190.636
#286	PITX1	8	9	17	716.49
#287	PEG3	8	14	22	1337.027
#288	GTF2H2	8	10	18	381.569
#289	IRF9	8	11	19	502.721
#290	ZIC2	8	15	23	1054.135
#291	MYCL1	8	14	22	1222.787
#292	CLOCK	8	16	24	773.337
#293	IRF2	8	7	15	266.531
#294	ZNF192	8	12	20	1408.124
#295	PTH	8	14	22	1170.111
#296	CBFA2T3	8	6	14	648.791
#297	MYC	8	20	28	3199.264
#298	VTN	8	14	22	531.73
#299	SNAPC4	8	17	25	1305.99
#300	ZHX3	8	8	16	646.725
#301	RCOR1	8	9	17	593.156
#302	TBX6	8	12	20	684.151
#303	HIRA	8	10	18	1359.561
#304	KLF10	8	12	20	3214.723
#305	ATF7	8	15	23	1762.82
#306	SREBF2	8	8	16	576.183
#307	ZEB1	8	11	19	1004.034
#308	PPARG	8	11	19	599.832
#309	TCF20	8	13	21	1315.518
#310	GTF2H4	7	13	20	1254.817
#311	EGR1	7	11	18	1407.369
#312	HLF	7	12	19	590.97
#313	E2F5	7	13	20	1011.597
#314	ZIC3	7	10	17	1542.27
#315	RBCK1	7	10	17	395.843
#316	FOXK2	7	12	19	1366.167
#317	ATF3	7	8	15	450.324
#318	RXRA	7	11	18	1091.496
#319	NKX2-1	7	7	14	1032.751
#320	NR1I2	7	10	17	365.702
#321	DMTF1	7	11	18	1378.87
#322	FOXD2	7	11	18	2289.831
#323	FOSB	7	7	14	367.421
#324	FOS	7	10	17	2626.239
#325	SIM2	7	17	24	2026.952
#326	HOXA1	7	9	16	1652.227
#327	CREB5	7	11	18	300.966
#328	SHOX	7	13	20	2101.159
#329	RUNX2	7	13	20	1141.694
#330	IRF8	7	13	20	728.74
#331	SOX5	7	13	20	1879.765
#332	ARID4A	7	6	13	654.789
#333	PDX1	7	13	20	1078.136
#334	HOXD4	6	13	19	1027.5
#335	BLZF1	6	18	24	1581.408
#336	ZNF35	6	8	14	276.741
#337	PBX1	6	14	20	605.586
#338	CBFB	6	12	18	379.867
#339	NR2F1	6	15	21	755.228
#340	RFXAP	6	14	20	762.918
#341	CRX	6	9	15	794.103
#342	ETS1	6	19	25	1524.331
#343	TRIM29	6	12	18	3058.859
#344	HNF4A	6	10	16	654.127
#345	NFKB1	6	17	23	2439.144
#346	NFATC3	6	17	23	773.08
#347	NR4A2	6	10	16	683.763
#348	HOXD9	6	12	18	911.935
#349	LMO4	6	14	20	799.879
#350	FOXE1	6	13	19	1145.079
#351	WT1	6	14	20	1148.747
#352	RFX1	6	10	16	465.855
#353	CNOT8	6	10	16	498.265
#354	TFCP2	6	11	17	649.097
#355	CITED1	6	10	16	953.039
#356	ZNF85	6	10	16	215.885
#357	HOXC11	6	12	18	692.483
#358	ETV5	6	14	20	1552.188
#359	NR6A1	6	14	20	2833.741
#360	RUNX1	6	13	19	1907.236
#361	ZNF268	6	8	14	872.483
#362	FOXF1	6	15	21	1174.685
#363	SATB1	6	11	17	691.11
#364	RUNX1T1	6	12	18	824.387
#365	TFE3	6	13	19	605.532
#366	GABPA	6	15	21	1021.378
#367	ZKSCAN1	6	19	25	1252.952
#368	ASCL2	6	14	20	842.724
#369	TFDP1	5	18	23	529.935
#370	PURA	5	22	27	521.491
#371	STAT1	5	14	19	898.769
#372	EN2	5	17	22	423.973
#373	ATF6B	5	15	20	1320.456
#374	RORB	5	15	20	1947.478
#375	CUX2	5	20	25	1297.803
#376	TCF7	5	11	16	213.918
#377	TAF13	5	17	22	2917.523
#378	MAFF	5	13	18	1015.018
#379	ZNF154	5	13	18	2091.794
#380	NFE2L1	5	6	11	243.855
#381	ESR2	5	15	20	565.64
#382	CITED2	5	14	19	1340.093
#383	TSC22D4	5	21	26	699.884
#384	ZNF174	5	13	18	723.929
#385	MEOX2	5	9	14	167.893
#386	HOXA2	5	12	17	447.098
#387	ZNF140	5	13	18	379.133
#388	SRY	5	12	17	1707.77
#389	ZNF148	5	14	19	512.916
#390	CREB3	5	18	23	713.269
#391	DDIT3	5	17	22	1036.429
#392	ZNF131	5	11	16	840.504
#393	SOX15	5	14	19	684.459
#394	EGR4	5	13	18	1350.43
#395	KLF12	5	7	12	252.701
#396	POU2F2	5	12	17	444.221
#397	PGR	5	15	20	1233.26
#398	TAF7	5	8	13	287.642
#399	ERF	5	14	19	907.723
#400	NFIL3	5	14	19	1089.029
#401	TCF7L2	4	13	17	309.389
#402	DLX2	4	11	15	2055.104
#403	POU4F2	4	15	19	530.069
#404	TFDP2	4	19	23	974.881
#405	MTA1	4	19	23	1275.515
#406	RORC	4	13	17	957.227
#407	POU6F1	4	12	16	637.048
#408	NKX2-8	4	13	17	577.418
#409	PITX2	4	14	18	476.046
#410	ZNF33B	4	15	19	1178.389
#411	FEV	4	21	25	612.546
#412	ZIC1	4	11	15	1365.196
#413	FOXJ2	4	14	18	2832.09
#414	SOX9	4	17	21	839.62
#415	MEIS3P1	4	15	19	2109.207
#416	SCAND2	4	14	18	246.354
#417	AR	4	14	18	925.197
#418	BNC1	4	18	22	284.349
#419	STAT2	4	17	21	1283.468
#420	NFKB2	4	9	13	1832.451
#421	RNF4	4	12	16	665.548
#422	AATF	4	16	20	284.294
#423	EMX1	4	16	20	428.591
#424	HMGA2	4	12	16	643.014
#425	TAF12	4	19	23	631.998
#426	ZNF197	3	16	19	693.494
#427	FOSL2	3	15	18	844.462
#428	HINFP	3	12	15	1572.252
#429	SNAPC2	3	9	12	499.128
#430	HOXA9	3	18	21	348.428
#431	SOX11	3	16	19	1335.523
#432	POU4F1	3	15	18	1750.169
#433	BTG2	3	9	12	394.44
#434	YY1	3	13	16	1217.412
#435	GATA6	3	13	16	480.892
#436	PBX3	3	9	12	219.345
#437	SOX1	3	10	13	660.58
#438	NR1H3	3	16	19	351.57
#439	NFATC1	3	24	27	665.175
#440	ELK4	3	10	13	1700.106
#441	ZNF45	3	9	12	348.88
#442	TCF3	3	13	16	209.715
#443	TAF1B	3	16	19	751.415
#444	IRX5	3	18	21	282.535
#445	ST18	3	18	21	693.92
#446	E2F4	3	18	21	332.926
#447	CTBP1	3	14	17	2712.933
#448	KLF11	3	14	17	1082.864
#449	SALL1	3	17	20	225.154
#450	JUND	3	18	21	893.68
#451	HOXA4	3	10	13	607.021
#452	RARG	3	9	12	349.077
#453	RB1	3	13	16	223.975
#454	SIX3	3	17	20	352.504
#455	NRL	3	18	21	1050.008
#456	PHTF1	2	12	14	116.202
#457	BACH1	2	15	17	3073.084
#458	HR	2	20	22	1284.368
#459	NR5A2	2	17	19	1279.281
#460	HOXB2	2	14	16	516.915
#461	ARNTL	2	20	22	549.809
#462	HOXA5	2	14	16	96.411
#463	FOXO4	2	15	17	379.983
#464	BCL6	2	14	16	996.519
#465	NR1D2	2	18	20	1589.851
#466	MYF5	2	15	17	1046.903
#467	LHX1	2	20	22	205.419
#468	PLAG1	2	18	20	1600.919
#469	PPBPL2	2	14	16	210.748
#470	NFE2L3	2	19	21	226.755
#471	HOXD1	2	8	10	871.549
#472	MECOM	2	18	20	1208.719
#473	ZNF81	2	9	11	291.75
#474	SIX1	2	17	19	367.366
#475	ZNF41	2	12	14	255.449
#476	TAL1	2	8	10	1314.842
#477	GBX2	2	14	16	502.381
#478	SMAD9	2	17	19	531.285
#479	WNT5A	2	16	18	225.393
#480	TBX5	1	13	14	176.297
#481	ETV4	1	16	17	269.965
#482	MEIS2	1	16	17	82.871
#483	PAX4	1	15	16	289.639
#484	SP1	1	13	14	100.011
#485	SP4	1	16	17	222.612
#486	ZNF165	1	15	16	1147.737
#487	SMAD3	1	13	14	143.408
#488	ERG	1	17	18	67.352
#489	HESX1	1	18	19	236.699
#490	CDKN2A	1	17	18	657.546
#491	OLIG2	1	16	17	111.289
#492	ZNF274	1	11	12	3371.122
#493	SMAD6	1	11	12	496.246
#494	ETV1	1	21	22	1253.298
#495	RARB	0	15	15	0
#496	NFAT5	0	17	17	0
#497	PBX2	0	25	25	0
#498	ASCL1	0	23	23	0
#499	PKNOX1	0	19	19	0
#500	RORA	0	19	19	0