Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF236	51	2	53	82.299
#2	ELK1	49	1	50	22.269
#3	E2F4	40	1	41	2117.61
#4	PHF1	34	7	41	1841.197
#5	HMX1	33	4	37	5507.605
#6	PKNOX2	32	5	37	12337.354
#7	REST	31	4	35	2487.818
#8	RARG	31	3	34	260.437
#9	TCF20	31	1	32	19.316
#10	TRIM28	30	7	37	1136.161
#11	SPDEF	29	5	34	871.414
#12	GBX1	29	7	36	6243.318
#13	ELK3	28	8	36	3575.544
#14	NFYC	27	11	38	55203.328
#15	FOXN3	26	7	33	696.492
#16	IKZF1	25	4	29	33173.416
#17	FOXF1	24	4	28	2966.483
#18	RCAN1	24	2	26	14929.43
#19	HOXC11	23	6	29	215.533
#20	MEF2C	23	5	28	869.298
#21	USF2	23	3	26	496.656
#22	JUND	22	6	28	24834.52
#23	SCML2	22	5	27	34315.036
#24	NPAS2	22	7	29	1704.553
#25	CREM	21	5	26	4988.579
#26	NFATC4	21	7	28	321.034
#27	TFCP2	21	7	28	6040.536
#28	RBCK1	21	7	28	3619.646
#29	PRRX2	20	6	26	1185.692
#30	STAT4	20	7	27	2338.918
#31	SOLH	20	8	28	5352.666
#32	CREBL2	20	6	26	1208.783
#33	TFEB	20	5	25	3702.582
#34	ZFP36L2	20	6	26	2080.659
#35	MLXIPL	19	2	21	407.944
#36	ZGPAT	19	8	27	4065.506
#37	HMGA2	19	5	24	21547.191
#38	PHOX2B	19	3	22	42524.894
#39	SOX13	18	8	26	1110.84
#40	TSC22D4	18	8	26	1132.625
#41	KLF10	18	8	26	3591.428
#42	NR3C1	18	7	25	1720.141
#43	ZNF217	18	8	26	770.195
#44	GATAD1	18	8	26	20168.767
#45	RXRB	18	6	24	286.963
#46	TCF4	18	5	23	740.638
#47	NKX3-1	18	4	22	2711.246
#48	NR1I2	18	10	28	1449.726
#49	HMG20A	18	6	24	304.179
#50	ATF2	17	7	24	464.383
#51	PPARG	17	7	24	7418.304
#52	YY1	17	6	23	1811.447
#53	SOX2	17	9	26	747.346
#54	HCFC1	17	4	21	569.683
#55	ADNP	17	8	25	6616.187
#56	TBX3	16	10	26	1807.729
#57	KLF15	16	9	25	431.336
#58	POU5F1B	16	5	21	831.469
#59	RUNX1T1	16	10	26	2076.678
#60	NR4A3	16	5	21	11250.397
#61	ZNF444	16	5	21	1740.405
#62	CREB3L1	16	5	21	617.107
#63	SP4	16	5	21	1175.743
#64	EVX1	16	4	20	262.139
#65	SOX15	16	5	21	865.235
#66	SP3	15	8	23	810.821
#67	MYT1	15	8	23	1011.981
#68	TSC22D2	15	7	22	2584.521
#69	MMP14	15	7	22	413.441
#70	MECOM	15	9	24	2022.707
#71	LHX3	15	4	19	437.604
#72	TBX5	15	9	24	3922.856
#73	ZEB1	15	3	18	842.41
#74	NPAT	15	3	18	1489.76
#75	TFAP4	15	9	24	2877.853
#76	HMG20B	15	9	24	6395.804
#77	NFKB2	15	4	19	1236.571
#78	MAFF	14	9	23	6633.865
#79	BTAF1	14	2	16	26.546
#80	GATA3	14	10	24	10623.647
#81	TCF7L1	14	9	23	2905.994
#82	FOXO4	14	4	18	117.974
#83	SMAD4	14	9	23	3462.649
#84	PCGF2	14	8	22	1551.287
#85	CEBPB	14	10	24	5306.312
#86	TBX6	14	8	22	2031.839
#87	ALX1	14	6	20	36465.292
#88	ZFPM2	14	4	18	1992.619
#89	PAX8	14	4	18	4074.812
#90	RARB	14	6	20	743.277
#91	HNRNPK	14	9	23	1604.956
#92	GLI3	14	5	19	4471.905
#93	LZTS1	14	4	18	421.953
#94	POU4F2	13	7	20	44742.623
#95	PLSCR1	13	10	23	3328.642
#96	HSF4	13	3	16	1074.831
#97	ZFHX3	13	14	27	4386.335
#98	ZEB2	13	11	24	3128.845
#99	RFXANK	13	6	19	696.641
#100	SMAD6	13	11	24	8024.88
#101	TFAM	13	9	22	1772.169
#102	MLX	13	7	20	726.617
#103	NFE2L2	13	10	23	5201.318
#104	SNAPC2	13	4	17	280.698
#105	ZNF207	13	10	23	2151.097
#106	EGR3	13	3	16	293.457
#107	ZNF287	13	9	22	34098.028
#108	DRAP1	13	11	24	8021.083
#109	ETV1	13	7	20	50171.191
#110	POU4F1	12	9	21	2762.472
#111	NR2F6	12	13	25	6137.713
#112	IRF8	12	9	21	2307.176
#113	MAFB	12	8	20	4673.513
#114	POU2F2	12	6	18	315.243
#115	TCF21	12	3	15	225.692
#116	PRDM2	12	9	21	38017.626
#117	ZNF83	12	7	19	981.804
#118	FUBP1	12	11	23	871.564
#119	HMGB1	12	8	20	7362.23
#120	TEAD4	12	6	18	4932.655
#121	ENO1	12	6	18	1474.936
#122	KLF7	12	5	17	6933.284
#123	CTCF	12	10	22	2011.639
#124	PEG3	12	11	23	2241.555
#125	HNF1B	12	5	17	382.884
#126	FLI1	12	8	20	1033.277
#127	ZNF3	12	9	21	252.312
#128	TSHZ2	11	10	21	417.355
#129	CEBPD	11	10	21	1925.743
#130	SLC30A9	11	4	15	393.368
#131	TP63	11	9	20	2943.479
#132	RELA	11	8	19	1461.089
#133	SMAD2	11	9	20	1191.437
#134	MEOX1	11	4	15	161.864
#135	ZKSCAN1	11	9	20	1456.885
#136	ELF1	11	8	19	1828.337
#137	TBX21	11	4	15	344.029
#138	NR1H2	11	8	19	1433.275
#139	SCAND1	11	6	17	5150.994
#140	GTF2H4	11	11	22	2260.873
#141	MYCL1	11	10	21	8324.553
#142	IRF3	10	11	21	1632.964
#143	T	10	8	18	33461.583
#144	NFIL3	10	6	16	776.449
#145	KLF9	10	8	18	1612.866
#146	RUNX3	10	6	16	815.973
#147	FEV	10	8	18	682.512
#148	FOXA1	10	3	13	1210.157
#149	TSC22D3	10	14	24	3001.904
#150	BTG2	10	11	21	2196.142
#151	HIF1A	10	9	19	5136.877
#152	RB1	10	6	16	1095.237
#153	TAL1	10	9	19	98.851
#154	HOXD4	10	7	17	1747.209
#155	CREB1	10	9	19	940.031
#156	SOX4	10	8	18	243.004
#157	ZNF446	10	5	15	489.63
#158	SOX10	10	9	19	864.504
#159	HOXA11	10	7	17	459.63
#160	ZKSCAN3	10	10	20	1307.892
#161	ATF6B	10	6	16	65.543
#162	MYOG	10	9	19	1703.728
#163	PRRX1	10	9	19	1444.527
#164	ZNF91	10	8	18	801.893
#165	TRIM29	10	14	24	7657.236
#166	ELF4	9	6	15	725.125
#167	RAX	9	6	15	1331.229
#168	GAS7	9	10	19	7923.764
#169	MEIS1	9	10	19	5040.008
#170	EPAS1	9	7	16	1619.972
#171	RORC	9	6	15	128.172
#172	LEF1	9	9	18	848.992
#173	CSDA	9	8	17	5503.096
#174	MYBL2	9	6	15	6989.339
#175	TBX2	9	11	20	2277.827
#176	NRL	9	8	17	1641.514
#177	ARNTL2	9	6	15	931.191
#178	TFCP2L1	9	8	17	12453.341
#179	KLF6	9	10	19	2326.137
#180	ZNF192	9	6	15	2028.687
#181	GCFC1	9	8	17	6784.91
#182	E2F1	9	5	14	520.623
#183	NFYB	9	12	21	1488.751
#184	MZF1	9	8	17	1948.569
#185	MEIS3P1	9	9	18	1683.747
#186	TCF3	9	8	17	3289.894
#187	ZNF277	9	7	16	2611.626
#188	RUNX2	9	9	18	1943.54
#189	TAF4	9	6	15	5700.19
#190	ETS2	9	12	21	5160.285
#191	ATF7	9	12	21	925.916
#192	EGR4	8	10	18	7098.102
#193	HAND1	8	7	15	2059.57
#194	TAF5L	8	7	15	957.853
#195	EDF1	8	9	17	1314.817
#196	HDAC1	8	2	10	194.445
#197	NR2F1	8	6	14	432.379
#198	SNAPC4	8	9	17	470.102
#199	ELF2	8	11	19	3752.026
#200	HDAC2	8	6	14	2723.454
#201	ATF1	8	9	17	3119.151
#202	NR4A2	8	3	11	325.249
#203	ZIC3	8	9	17	3119.359
#204	HOXB6	8	6	14	13077.14
#205	AEBP1	8	17	25	3218.694
#206	NR3C2	8	9	17	624.632
#207	ISL1	8	9	17	3563.599
#208	NR1D2	8	7	15	16532.644
#209	NR4A1	8	8	16	1618.456
#210	ATF3	8	5	13	1524.747
#211	CREBZF	8	13	21	2418.034
#212	BACH1	8	9	17	3093.063
#213	TCF15	8	8	16	358.952
#214	HOXA1	8	10	18	770.785
#215	ESRRA	8	7	15	173.682
#216	SIX1	8	11	19	1239.405
#217	SNAI2	8	15	23	8669.763
#218	PPBPL2	8	9	17	4558.998
#219	STAT5A	8	12	20	1809.66
#220	PURA	8	10	18	1606.856
#221	AFF1	8	7	15	7327.631
#222	SALL2	8	10	18	913.065
#223	ZNF219	8	11	19	3148.582
#224	TSC22D1	7	14	21	924.976
#225	ATF5	7	11	18	4702.295
#226	ETV4	7	10	17	827.268
#227	JUN	7	6	13	2849.798
#228	HOXB1	7	7	14	397.011
#229	NFIB	7	14	21	3588.911
#230	FOSB	7	6	13	636.749
#231	BHLHE41	7	13	20	1005.598
#232	MEIS2	7	11	18	1408.159
#233	HIC1	7	10	17	1458.605
#234	BCL3	7	9	16	905.338
#235	MEF2D	7	9	16	577.511
#236	ESR1	7	10	17	1947.887
#237	ZBTB38	7	4	11	60.776
#238	CDX2	7	3	10	63.587
#239	HNRNPAB	7	2	9	69.198
#240	HOXD1	7	10	17	1508.603
#241	AHR	7	5	12	2092.306
#242	E4F1	7	12	19	539.625
#243	GATA6	7	8	15	1112.895
#244	FOXM1	7	8	15	950.41
#245	ZNF148	7	9	16	1209.723
#246	HOXB2	7	4	11	2182.419
#247	FOXJ2	7	7	14	825.411
#248	NR2C1	7	11	18	1464.437
#249	BUD31	7	9	16	1056.077
#250	ERG	7	6	13	788.66
#251	YEATS4	7	8	15	4604.766
#252	HOXB5	7	11	18	4499.408
#253	CREB3L2	7	10	17	955.479
#254	CNOT8	6	8	14	6265.311
#255	CBFB	6	9	15	6709.12
#256	HLF	6	10	16	1206.52
#257	ZNF500	6	4	10	167.823
#258	HR	6	6	12	189.922
#259	STRN3	6	12	18	582.483
#260	TWIST1	6	13	19	2067.659
#261	HOXB3	6	6	12	161.034
#262	MSX2	6	13	19	930.068
#263	IRF4	6	6	12	807.248
#264	ATF6	6	12	18	2030.279
#265	MAF	6	13	19	4929.359
#266	FOS	6	4	10	149.499
#267	GTF2I	6	10	16	419.865
#268	KDM5B	6	9	15	1254.868
#269	AHCTF1	6	7	13	322.755
#270	MTA1	6	10	16	750.63
#271	IRF7	6	10	16	5048.543
#272	EGR2	6	9	15	583.526
#273	CREB5	6	9	15	343.002
#274	SREBF2	6	9	15	2599.922
#275	LZTR1	6	4	10	593.916
#276	MYC	6	11	17	16619.301
#277	NEUROD2	6	11	17	2766.531
#278	TAF12	6	12	18	785.575
#279	SATB2	6	10	16	958.512
#280	MEF2A	6	7	13	1048.357
#281	IRF1	6	8	14	1309.108
#282	ZFP36L1	5	16	21	14820.815
#283	HMGB2	5	13	18	1283.308
#284	REL	5	6	11	411.798
#285	STAT1	5	10	15	775.68
#286	TBX1	5	11	16	2466.804
#287	ELF5	5	9	14	5020.135
#288	TP53	5	9	14	361.281
#289	YBX1	5	10	15	523.701
#290	RBPJ	5	8	13	2325.544
#291	E2F3	5	6	11	5027.448
#292	TAF7	5	9	14	8332.114
#293	ZNF238	5	9	14	531.549
#294	ZNF131	5	7	12	362.045
#295	NFATC1	5	9	14	951.876
#296	BRD8	5	6	11	133.305
#297	NR6A1	5	8	13	507.023
#298	RXRA	5	9	14	2151.074
#299	TAF4B	5	12	17	1930.528
#300	SATB1	5	10	15	1668.449
#301	ZSCAN16	5	9	14	1431.747
#302	LHX6	5	2	7	5.694
#303	STAT6	5	9	14	446.216
#304	HSF1	5	12	17	994.315
#305	IRF2	5	7	12	227.171
#306	NANOG	5	7	12	1204.812
#307	BACH2	5	14	19	2169.896
#308	POU6F1	5	5	10	445.915
#309	TFAP2C	5	8	13	380.412
#310	ZNF215	5	11	16	2212.373
#311	TAF6	5	12	17	17466.051
#312	ZNF394	4	4	8	752.358
#313	HOXA5	4	13	17	2504.843
#314	KLF5	4	11	15	1708.261
#315	BHLHE40	4	13	17	1140.08
#316	SOX9	4	12	16	901.87
#317	PBX1	4	14	18	4295.582
#318	TCF7L2	4	10	14	585.344
#319	HOPX	4	15	19	13080.118
#320	BLZF1	4	9	13	272.051
#321	SIM2	4	7	11	5398.315
#322	PAX4	4	9	13	2102.98
#323	HMBOX1	4	9	13	9452.752
#324	C2orf3	4	11	15	1537.69
#325	BARX1	4	11	15	1117.749
#326	NR2F2	4	12	16	234.002
#327	SLC2A4RG	4	6	10	670.068
#328	PTTG1	4	13	17	3434.929
#329	ZNF189	4	6	10	641.708
#330	TBX4	4	9	13	286.056
#331	RARA	4	7	11	771.229
#332	NCOR1	4	13	17	834.812
#333	SOX11	4	9	13	1322.773
#334	CNOT7	4	7	11	1336.823
#335	VDR	4	9	13	436.984
#336	HOXC10	4	10	14	937.727
#337	IRF6	4	8	12	2569.592
#338	TCFL5	4	7	11	6739.787
#339	ASCL1	4	6	10	92.576
#340	RCOR1	4	12	16	280.569
#341	SIX5	4	4	8	102.391
#342	ETV5	4	12	16	1552.752
#343	ZNF140	4	9	13	3770.837
#344	STAT2	3	10	13	1591.691
#345	SALL1	3	12	15	582.256
#346	CREBBP	3	8	11	1572.594
#347	MLLT10	3	8	11	324.724
#348	ZBTB48	3	11	14	433.853
#349	FOXJ1	3	11	14	1081.816
#350	KDM5A	3	9	12	166.421
#351	UBP1	3	8	11	641.578
#352	POU3F1	3	7	10	762.969
#353	BCL6	3	14	17	257.067
#354	TFAP2A	3	13	16	3965.839
#355	NOTCH1	3	7	10	179.85
#356	ZNF281	3	10	13	1950.652
#357	EHF	3	9	12	133.528
#358	FOXO3	3	7	10	2615.072
#359	FOXD1	3	8	11	2436.578
#360	SOX12	3	8	11	2024.025
#361	PA2G4	3	9	12	655.453
#362	TAF10	3	14	17	4616.642
#363	XBP1	3	10	13	2435.397
#364	HOXA10	3	5	8	1661.884
#365	ST18	3	9	12	3533.481
#366	SUPT4H1	3	7	10	224.635
#367	TGIF1	3	7	10	1383.211
#368	TFEC	3	9	12	1179.395
#369	HES1	3	8	11	306.996
#370	KLF4	3	9	12	206.359
#371	SPIB	3	8	11	1084.904
#372	DLX2	3	10	13	607.115
#373	FOSL1	3	12	15	779.232
#374	IRF9	3	8	11	390.747
#375	PBX2	3	6	9	642.429
#376	TCF12	3	12	15	689.017
#377	SCAND2	3	11	14	1435.581
#378	RUNX1	3	5	8	152.111
#379	CSRNP2	3	7	10	2569.315
#380	ATF4	3	11	14	1499.69
#381	HOXD3	3	8	11	1664.274
#382	KLF2	3	10	13	409.599
#383	TRPS1	3	13	16	725.98
#384	SPI1	3	8	11	581.872
#385	EMX1	3	12	15	1164.733
#386	UBN1	3	7	10	120.937
#387	CNBP	3	5	8	178.752
#388	MSRB2	3	5	8	784.513
#389	ZNF154	3	7	10	258.997
#390	CEBPA	3	14	17	2422.978
#391	HMGA1	3	11	14	2377.46
#392	RFX5	3	6	9	1030.603
#393	GATA2	3	8	11	249.275
#394	CTBP1	3	11	14	716.057
#395	CUX1	3	6	9	159.339
#396	MNX1	3	11	14	1856.962
#397	HOXC8	3	9	12	974.359
#398	PRDM1	3	7	10	266.164
#399	PITX2	3	6	9	141.097
#400	ELF3	2	11	13	584.643
#401	ZNF274	2	9	11	1635.259
#402	HIF3A	2	7	9	491.681
#403	RERE	2	12	14	232.845
#404	ZNF167	2	9	11	81.331
#405	LMO4	2	13	15	854.021
#406	TFDP1	2	8	10	79.538
#407	ZNF93	2	12	14	516.799
#408	GTF2H3	2	10	12	959.201
#409	ZNF117	2	12	14	7146.229
#410	AR	2	9	11	358.713
#411	ZSCAN18	2	10	12	1915.537
#412	SREBF1	2	6	8	388.646
#413	HEY1	2	11	13	9655.372
#414	STAT3	2	8	10	645.107
#415	ZHX2	2	14	16	1318.673
#416	SCML1	2	15	17	3083.838
#417	CBL	2	10	12	98.54
#418	NFAT5	2	8	10	221.241
#419	FOXO1	2	5	7	779.759
#420	SMAD3	2	7	9	911.645
#421	TP73	2	13	15	105.425
#422	CBFA2T2	2	12	14	1084.597
#423	MYCN	2	8	10	321.955
#424	E2F5	2	9	11	329.702
#425	HSF2	2	6	8	43.264
#426	GRHL2	2	5	7	650.669
#427	PPARD	2	6	8	4161.144
#428	NR1H4	2	7	9	1005.088
#429	HNF4G	2	8	10	628.148
#430	JUNB	2	9	11	346.454
#431	MGA	2	14	16	219.448
#432	MAX	2	8	10	668.169
#433	TCEAL1	2	10	12	956.411
#434	NFE2L3	2	7	9	253.867
#435	OVOL1	2	7	9	610.58
#436	SIX2	2	8	10	1616.483
#437	ZNF165	2	6	8	982.281
#438	HOXC5	2	8	10	301.258
#439	CITED2	2	10	12	174.602
#440	PITX1	2	10	12	8145.46
#441	E2F8	2	14	16	1312.898
#442	TRIM22	2	12	14	1585.658
#443	WNT5A	2	15	17	4110.179
#444	IRX5	2	9	11	7595.185
#445	HCLS1	2	11	13	153.349
#446	ZNF323	2	7	9	1551.303
#447	HOXA9	2	12	14	2931.313
#448	ZNF35	2	4	6	209.541
#449	ETV2	2	10	12	287.746
#450	FOXG1	2	14	16	2143.86
#451	PLAG1	2	8	10	8110.52
#452	ATOH1	2	5	7	64.019
#453	MLL	2	8	10	2319.816
#454	SHOX	2	4	6	11.831
#455	SOX17	2	6	8	181.448
#456	LASS6	2	8	10	615.098
#457	EGR1	2	9	11	284.696
#458	HOXB7	2	13	15	929.479
#459	RORA	1	5	6	177.975
#460	HEY2	1	9	10	335.459
#461	MNT	1	7	8	550.434
#462	CDKN2A	1	9	10	108.385
#463	ESRRG	1	7	8	21.442
#464	ZNF175	1	10	11	1385.16
#465	NFYA	1	10	11	131.259
#466	FOXP3	1	9	10	816.395
#467	TCF25	1	6	7	473.286
#468	ZNF132	1	9	10	45.279
#469	MITF	1	12	13	119.308
#470	CCRN4L	1	6	7	64.884
#471	SRF	1	8	9	61.438
#472	PHTF1	1	10	11	808.76
#473	TFAP2B	1	11	12	854.706
#474	DDIT3	1	7	8	8.255
#475	CTNNB1	1	7	8	38.853
#476	NFATC3	1	10	11	127.774
#477	ZFHX4	1	12	13	96.987
#478	BCL11B	1	11	12	2356.797
#479	ETV7	1	7	8	5.467
#480	SMAD1	1	9	10	409.532
#481	FOXF2	1	4	5	40.905
#482	TARDBP	1	6	7	494.272
#483	PBX3	1	7	8	763.092
#484	TCF7	1	5	6	52.292
#485	DMTF1	1	5	6	398.719
#486	TEAD3	1	12	13	222.038
#487	FOSL2	1	11	12	2457.162
#488	ADNP2	1	9	10	54.011
#489	HIRA	1	6	7	41.513
#490	ARNT2	1	5	6	3193.559
#491	MSC	1	7	8	1116.36
#492	ZNF45	0	9	9	0
#493	NR1H3	0	7	7	0
#494	NFE2	0	11	11	0
#495	TFE3	0	9	9	0
#496	KLF11	0	13	13	0
#497	HHEX	0	9	9	0
#498	HAND2	0	9	9	0
#499	FOXC1	0	11	11	0
#500	SPEN	0	9	9	0