Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GTF2I	76	1	77	1164.377
#2	ZNF277	60	1	61	11.862
#3	YBX1	56	4	60	303.813
#4	ENO1	55	3	58	748.771
#5	KLF10	53	7	60	1957.16
#6	MEIS1	51	5	56	2378.953
#7	SMAD4	51	4	55	270.632
#8	ZNF281	48	0	48	0
#9	NFIC	44	2	46	34.691
#10	RUNX1T1	42	5	47	166.143
#11	SNAI2	42	0	42	0
#12	BATF3	42	12	54	2116.652
#13	ZNF45	42	12	54	3370.277
#14	FLI1	39	8	47	1576.652
#15	REL	39	10	49	753.533
#16	ZEB2	39	4	43	302.273
#17	NR2F2	38	13	51	1922.501
#18	ZNF444	38	10	48	1270.317
#19	FOSL2	37	6	43	1227.439
#20	SOX17	36	10	46	2551.124
#21	ZNF131	36	8	44	385.73
#22	TRIM22	36	8	44	580.957
#23	PAX8	35	13	48	2483.754
#24	RXRB	35	6	41	332.316
#25	ETV5	35	10	45	1874.75
#26	POU6F1	35	10	45	1425.389
#27	TCF7L2	34	5	39	2027.504
#28	KLF2	34	10	44	919.547
#29	SP1	34	12	46	899.866
#30	MEF2C	34	12	46	1994.742
#31	MECOM	33	13	46	1632.766
#32	NFATC4	33	8	41	602.388
#33	IRF8	33	6	39	857.388
#34	ETS1	33	10	43	1778.347
#35	GABPA	32	10	42	1896.134
#36	TFDP3	32	10	42	1497.741
#37	NR5A1	32	14	46	965.124
#38	ZNF148	32	6	38	1268.137
#39	FBXW7	31	6	37	1388.306
#40	STAT3	31	11	42	883.166
#41	HIF1A	30	4	34	1111.316
#42	PTTG1	29	7	36	681.695
#43	HOXA1	29	8	37	1240.28
#44	BHLHE40	29	8	37	1297.732
#45	E2F1	29	8	37	967.273
#46	SCML1	29	13	42	2163.047
#47	PITX3	28	6	34	1402.895
#48	HOXA7	28	18	46	4520.06
#49	NFYB	28	5	33	1687.174
#50	CEBPD	28	12	40	1836.281
#51	MSC	28	8	36	731.423
#52	AFF1	28	9	37	1568.344
#53	WT1	28	16	44	4563.516
#54	ELK3	28	11	39	903.949
#55	TCF4	27	8	35	753.883
#56	TBR1	27	18	45	2066.373
#57	RARA	27	7	34	1297.354
#58	HCLS1	27	5	32	937.132
#59	TFEC	26	9	35	519.978
#60	ZNF140	26	8	34	1455.147
#61	GLI2	26	9	35	1063.605
#62	NOLC1	26	8	34	2694.587
#63	HMX1	26	13	39	2811.369
#64	NFYC	25	9	34	2405.058
#65	FOXP3	25	7	32	1478.361
#66	MYF6	25	11	36	1109.25
#67	HSF2	25	10	35	1221.983
#68	ONECUT2	25	12	37	2701.825
#69	EHF	25	11	36	1542.057
#70	EGR3	25	5	30	328.594
#71	FOXO1	24	3	27	47.246
#72	HOXD10	24	6	30	946.075
#73	KLF4	24	13	37	1378.075
#74	MEOX2	24	12	36	1147.928
#75	STAT6	24	12	36	1101.006
#76	LZTS1	23	10	33	643.357
#77	NR2E1	23	7	30	705.672
#78	NFIX	23	13	36	2057.752
#79	AEBP1	23	2	25	38.876
#80	MAX	23	9	32	283.256
#81	JUNB	23	7	30	886.951
#82	CSDA	23	12	35	1253.466
#83	HES1	23	6	29	291.639
#84	POU3F2	23	10	33	2519.247
#85	PPARA	23	16	39	3312.774
#86	MAFG	23	7	30	272.915
#87	VSX1	23	12	35	421.602
#88	TCFL5	23	10	33	2272.529
#89	BCL6	22	7	29	530.525
#90	TP73	22	10	32	1377.726
#91	CITED1	22	12	34	3739.392
#92	CEBPE	22	14	36	2131.218
#93	RFXANK	22	14	36	1105.584
#94	CDKN2A	22	14	36	1122.674
#95	C2orf3	22	10	32	1413.093
#96	HOXA5	22	11	33	734.027
#97	SNAPC4	21	10	31	206.693
#98	EMX1	21	13	34	1547.527
#99	PURA	21	6	27	130.136
#100	TCF3	21	13	34	614.602
#101	CBFB	21	15	36	2645.091
#102	ZFHX3	21	16	37	2523.381
#103	PBX1	21	14	35	1965.75
#104	NR2F6	21	7	28	613.96
#105	PRRX1	21	5	26	175.231
#106	LMO4	21	13	34	2401.241
#107	TFDP1	20	8	28	210.824
#108	HCFC1	20	14	34	675.436
#109	SOX11	20	14	34	1265.415
#110	HMGA2	20	14	34	1157.214
#111	STAT1	20	14	34	1269.888
#112	NPAS1	20	10	30	1188.463
#113	HNF4G	19	14	33	2062.916
#114	NFYA	19	9	28	533.557
#115	ATF3	19	7	26	397.734
#116	HOXD12	19	10	29	1700.067
#117	POU3F3	19	11	30	701.116
#118	HOXA11	19	12	31	2272.749
#119	ELF3	19	14	33	1363.815
#120	MAFB	19	9	28	500.411
#121	SMAD6	19	14	33	2501.282
#122	EGR1	19	6	25	580.453
#123	TFEB	18	21	39	3417.857
#124	WNT5A	18	9	27	1104.53
#125	RUNX1	18	13	31	931.551
#126	HMG20B	18	13	31	1060.188
#127	MZF1	18	20	38	2110.237
#128	HOPX	18	12	30	956.71
#129	ZHX3	18	16	34	1057.511
#130	NKX2-5	18	15	33	2062.591
#131	TADA3	18	10	28	1665.445
#132	TFAP2B	17	11	28	1156.945
#133	MSX1	17	22	39	3869.283
#134	ZBTB48	17	17	34	701.097
#135	HOXB13	17	6	23	883.248
#136	BCL3	17	15	32	788.973
#137	PLSCR1	17	9	26	886.552
#138	EGR4	17	14	31	1106.741
#139	CREB3L1	17	12	29	787.069
#140	FOXL2	17	10	27	1078.055
#141	BUD31	17	14	31	1073.857
#142	TFAP2C	17	16	33	1305.309
#143	KLF9	17	10	27	1155.412
#144	GCM1	17	13	30	747.46
#145	TCF21	17	11	28	925.908
#146	FOS	17	8	25	509.34
#147	MYBL2	16	7	23	550.085
#148	GAS7	16	15	31	1005
#149	SIX5	16	12	28	1007.587
#150	ZNF91	16	16	32	2270.325
#151	NR3C1	16	16	32	1551.611
#152	CTBP1	16	17	33	803.491
#153	ZNF434	16	15	31	979.81
#154	ALX1	16	12	28	1357.666
#155	NR1I2	16	13	29	449.095
#156	ETV1	16	12	28	1874.52
#157	ZNF80	16	12	28	1658.837
#158	GATA4	16	9	25	359.665
#159	SLC26A3	16	13	29	1894.515
#160	ZFPM2	16	13	29	837.335
#161	FOXO3	16	12	28	566.902
#162	PEG3	16	10	26	439.952
#163	AHR	16	15	31	1417.23
#164	MMP14	16	10	26	566.186
#165	NR5A2	16	15	31	1302.716
#166	MAFK	16	11	27	691.676
#167	ZNF268	16	9	25	313.128
#168	HIC1	16	13	29	941.429
#169	NR2F1	15	14	29	1177.465
#170	TFDP2	15	12	27	608.174
#171	NR1H4	15	17	32	1060.274
#172	MNX1	15	23	38	3692.007
#173	SPDEF	15	14	29	1513.43
#174	PLAG1	15	11	26	849.89
#175	TLX2	15	9	24	1558.17
#176	ARNT	15	14	29	764.974
#177	TFE3	15	15	30	702.67
#178	ZBTB17	15	10	25	1003.997
#179	ZNF93	15	10	25	816.774
#180	FOXI1	15	14	29	1528.413
#181	MYF5	14	15	29	1358.862
#182	SPI1	14	13	27	792.866
#183	E2F8	14	12	26	1148.053
#184	ELK1	14	15	29	876.952
#185	HMBOX1	14	11	25	699.218
#186	NFX1	14	16	30	1369.575
#187	HOXB3	14	11	25	449.976
#188	ARID3A	14	17	31	2018.758
#189	RORB	14	10	24	894.203
#190	PHTF1	14	13	27	2009.186
#191	GBX2	14	16	30	962.242
#192	CITED2	14	16	30	808.643
#193	GATA6	14	20	34	2486.831
#194	THRA	14	24	38	2065.12
#195	MAFF	14	11	25	469.527
#196	FOXN3	14	11	25	862.071
#197	POU6F2	14	8	22	451.914
#198	TCF12	14	18	32	1625.531
#199	RFXAP	14	18	32	2240.113
#200	FOSB	14	2	16	285.764
#201	HMGA1	14	13	27	394.423
#202	HOXB2	14	11	25	1255.049
#203	HLF	14	17	31	674.498
#204	ESRRB	14	18	32	966.995
#205	SMAD5	14	15	29	522.26
#206	SCRT1	13	15	28	1312.543
#207	KLF6	13	19	32	1421.907
#208	NR3C2	13	13	26	1335.31
#209	FOXC1	13	18	31	1298.027
#210	MYC	13	15	28	1392.665
#211	HMGB2	13	9	22	546.993
#212	RERE	13	18	31	836.842
#213	BATF	13	13	26	741.531
#214	HOXD4	13	14	27	1158.019
#215	FOXC2	13	19	32	1243.438
#216	HOXC13	13	16	29	1290.97
#217	MXD1	13	19	32	1380.34
#218	RCAN1	13	18	31	1010.261
#219	NFIB	13	19	32	1345.663
#220	BCL11B	13	10	23	670.035
#221	RAX	13	19	32	731.581
#222	MYOD1	13	8	21	166.623
#223	BHLHE41	13	15	28	1188.159
#224	KDM5B	13	19	32	1748.273
#225	ECSIT	13	10	23	1592.354
#226	PHOX2B	12	14	26	672.127
#227	HR	12	16	28	857.915
#228	SATB2	12	14	26	884.786
#229	FOXH1	12	20	32	2953.315
#230	BNC1	12	15	27	781.093
#231	PPBPL2	12	16	28	1175.039
#232	HOXB6	12	13	25	674.225
#233	GSC2	12	17	29	1154.901
#234	HIRA	12	11	23	746.163
#235	CTNNB1	12	9	21	1132.345
#236	PAX7	12	13	25	1135.645
#237	CREBZF	12	14	26	2171.259
#238	SPEN	12	11	23	385.425
#239	ZNF238	12	18	30	1896.691
#240	NKX6-1	12	14	26	806.479
#241	SATB1	12	20	32	1526.496
#242	ASCL1	12	17	29	2155.508
#243	ZSCAN12	12	13	25	818.754
#244	FOSL1	12	24	36	1044.09
#245	SMAD9	12	13	25	802.088
#246	HEY2	12	14	26	780.642
#247	TP53	11	12	23	571.972
#248	MYCL1	11	17	28	1062.978
#249	OVOL1	11	14	25	1185.124
#250	HOXD3	11	16	27	593.826
#251	CSRNP3	11	19	30	901.818
#252	HEY1	11	16	27	504.313
#253	ZNF165	11	12	23	636.196
#254	KLF12	11	19	30	968.684
#255	ELF4	11	24	35	1592.266
#256	TEAD4	11	11	22	820.742
#257	ISL1	11	17	28	1001.184
#258	TBX19	11	16	27	1827.109
#259	AR	11	16	27	1178.073
#260	GRHL2	11	13	24	1566.761
#261	POU5F1B	11	14	25	833.311
#262	ZNF167	11	18	29	945.649
#263	PRDM2	11	21	32	1697.084
#264	TBX5	11	15	26	2181.235
#265	ARNTL	11	18	29	2156.037
#266	TWIST1	11	22	33	639.137
#267	IKZF1	11	12	23	677.439
#268	ARNT2	11	17	28	548.895
#269	LEF1	11	22	33	1132.996
#270	NR4A1	11	10	21	401.631
#271	ZNF135	11	17	28	1656.411
#272	ZNF117	11	11	22	484.013
#273	ZHX2	10	14	24	1049.675
#274	FOXD2	10	14	24	1828.666
#275	ZEB1	10	11	21	540.411
#276	CBFA2T2	10	15	25	736.449
#277	TBX6	10	16	26	500.272
#278	SCAND2	10	16	26	910.821
#279	FOXA2	10	20	30	1250.46
#280	ZNF639	10	19	29	1839.676
#281	BTG2	10	23	33	1359.442
#282	EGR2	10	15	25	440.409
#283	XBP1	10	14	24	1114.942
#284	EN2	10	12	22	733.449
#285	VTN	10	19	29	1027.944
#286	RARB	10	14	24	1311.905
#287	TSC22D2	10	16	26	808.624
#288	ELF1	10	14	24	855.806
#289	RB1	10	15	25	1237.185
#290	HESX1	10	11	21	575.871
#291	IRF7	10	11	21	441.029
#292	ZFP36L2	10	12	22	306.067
#293	PKNOX1	10	17	27	943.474
#294	SNAPC5	10	15	25	809.667
#295	IKZF3	10	13	23	1099.384
#296	PITX2	10	17	27	1055.872
#297	MTA2	10	19	29	777.297
#298	DBP	10	17	27	1778.157
#299	MYOG	10	9	19	330.524
#300	ZNF323	10	16	26	889.059
#301	HOXA4	10	6	16	396.168
#302	TBX1	10	19	29	804.557
#303	HOXD9	10	12	22	455.54
#304	ZGPAT	10	17	27	1068.878
#305	PRDM1	9	16	25	555.031
#306	HOXC10	9	22	31	1759.51
#307	POU3F1	9	18	27	1162.698
#308	ARNTL2	9	13	22	582.833
#309	SOLH	9	11	20	755.115
#310	SIX1	9	22	31	934.398
#311	TRIM29	9	18	27	988.052
#312	REST	9	23	32	1274.922
#313	SOX2	9	16	25	766.804
#314	ELF5	9	23	32	2170.649
#315	ZSCAN18	9	13	22	554.785
#316	TBX4	9	11	20	877.785
#317	POU4F1	9	13	22	363.811
#318	PDX1	9	17	26	1385.171
#319	DLX2	9	12	21	1308.501
#320	MLLT10	9	17	26	1114.371
#321	ELK4	9	17	26	847.742
#322	ONECUT1	9	13	22	713.959
#323	SOX4	9	18	27	1082.08
#324	ATF6	9	15	24	2251.629
#325	ZXDC	9	15	24	622.18
#326	YEATS4	9	14	23	911.349
#327	E2F5	9	20	29	1196.319
#328	SIX3	9	15	24	1978.74
#329	FOXO4	9	13	22	1317.058
#330	TAF4	9	21	30	1101.899
#331	HOXB1	9	18	27	1251.532
#332	YY1	9	17	26	884.994
#333	MLL	9	12	21	329.348
#334	PAX6	9	23	32	2474.187
#335	ETV4	9	15	24	630.321
#336	ST18	9	14	23	1202.863
#337	IRF4	9	21	30	1187.322
#338	NR6A1	8	8	16	107.145
#339	HOXD1	8	11	19	908.212
#340	IRX4	8	15	23	655.875
#341	HOXB9	8	16	24	1070.196
#342	FOXJ1	8	15	23	425.097
#343	SALL1	8	22	30	1137.705
#344	EN1	8	10	18	437.801
#345	KDM5A	8	12	20	178.44
#346	NPAT	8	16	24	1608.584
#347	NR2C1	8	18	26	1096.529
#348	DMRT1	8	21	29	861.221
#349	LHX6	8	23	31	1788.61
#350	TCF15	8	15	23	1879.541
#351	SMAD3	8	23	31	1993.653
#352	MAF	8	15	23	508.934
#353	ETV2	8	19	27	1837.051
#354	C11orf9	8	15	23	973.744
#355	IRF5	8	8	16	225.692
#356	POU2F2	8	13	21	1225.591
#357	POU2F3	8	19	27	1418
#358	ZNF155	8	9	17	724.121
#359	NFKB2	8	18	26	585.716
#360	ATF5	8	14	22	558.732
#361	PAX5	8	16	24	415.149
#362	JUND	8	10	18	404.245
#363	FOXE1	8	17	25	1171.158
#364	RUNX3	8	18	26	801.787
#365	PROX1	8	19	27	601.908
#366	ATF6B	8	18	26	1208.454
#367	ZFP37	8	13	21	580.048
#368	CREBBP	8	18	26	806.208
#369	TFAP4	8	18	26	673.101
#370	POU3F4	8	15	23	391.962
#371	ZNF154	8	12	20	400.779
#372	ASCL2	8	11	19	647.927
#373	HOXD11	8	17	25	1251.945
#374	ZNF446	8	21	29	631.579
#375	SIM2	8	16	24	879.26
#376	CEBPA	7	13	20	487.026
#377	FOXA1	7	19	26	2204.614
#378	NFAT5	7	18	25	718.751
#379	TSHZ2	7	12	19	512.636
#380	ZNF41	7	16	23	1130.082
#381	ZNF643	7	23	30	957.204
#382	TRPS1	7	14	21	691.244
#383	SOX9	7	15	22	486.944
#384	HNF1A	7	16	23	1051.499
#385	HIF3A	7	14	21	460.522
#386	NEUROD1	7	19	26	882.576
#387	NKX3-2	7	10	17	319.232
#388	NKX2-8	7	19	26	467.22
#389	ERG	7	16	23	349.271
#390	PGR	7	19	26	938.731
#391	ZNF236	7	20	27	515.704
#392	LHX2	7	19	26	702.989
#393	HOXA10	7	17	24	1347.467
#394	PKNOX2	7	18	25	879.528
#395	KLF5	7	11	18	197.239
#396	RXRA	7	20	27	1512.282
#397	NR2E3	7	16	23	656.484
#398	PAX4	7	21	28	1557.434
#399	OLIG2	6	16	22	634.32
#400	CUX2	6	17	23	551.196
#401	NR0B1	6	18	24	1165.267
#402	LHX1	6	24	30	1732.707
#403	FOXM1	6	13	19	447.354
#404	CREM	6	14	20	425.982
#405	ZNF202	6	16	22	2043.276
#406	POU4F3	6	16	22	720.847
#407	VDR	6	18	24	1730.353
#408	RARG	6	17	23	2358.223
#409	MYT1L	6	20	26	1943.198
#410	MSRB2	6	22	28	964.93
#411	SUPT6H	6	15	21	435.739
#412	NFATC1	6	17	23	951.811
#413	ZNF3	6	17	23	763.007
#414	FOXD3	6	17	23	380.105
#415	TADA2A	6	19	25	894.943
#416	GATA2	6	22	28	629.097
#417	PTH	6	20	26	872.297
#418	BRD8	6	17	23	967.305
#419	HOXB8	6	15	21	857.462
#420	HOXA3	6	13	19	560.739
#421	MSX2	6	19	25	1184.409
#422	MYCN	6	25	31	1231.269
#423	ZSCAN2	6	11	17	439.973
#424	FOXG1	6	20	26	1031.09
#425	TBX3	6	23	29	622.41
#426	SOX5	5	25	30	395.572
#427	HSF4	5	16	21	494.361
#428	NEUROG1	5	17	22	530.68
#429	PAX3	5	16	21	816.816
#430	SOX15	5	11	16	667.225
#431	TP63	5	20	25	746.894
#432	ESR1	5	22	27	476.263
#433	JUN	5	15	20	562.068
#434	SOX30	5	18	23	646.789
#435	NR4A3	5	14	19	675.6
#436	STAT2	5	15	20	427.728
#437	TAF13	5	20	25	464.966
#438	TFAP2A	5	22	27	1243.119
#439	HNF4A	5	19	24	337.331
#440	HOXA2	5	12	17	401.515
#441	PRRX2	5	18	23	1108.687
#442	ZIC3	5	21	26	829.751
#443	NANOG	5	21	26	692.22
#444	TAF12	5	19	24	800.259
#445	MBD1	5	11	16	341.55
#446	MYT1	5	11	16	438.749
#447	HOXC8	5	19	24	711.464
#448	FOXB1	5	16	21	389.838
#449	NPAS2	5	19	24	819.494
#450	NR4A2	4	14	18	269.069
#451	HOXA9	4	12	16	250.036
#452	MEF2D	4	21	25	552.482
#453	NKX2-1	4	12	16	220.583
#454	TCF7	4	20	24	664.806
#455	SRY	4	12	16	680.077
#456	PPARD	4	17	21	840.496
#457	SOX18	4	16	20	525.808
#458	TEF	4	19	23	357.133
#459	DLX6	4	20	24	923.131
#460	MEIS2	4	22	26	655.71
#461	ESRRG	4	23	27	702.487
#462	ZNF287	3	16	19	1032.275
#463	HOXB7	3	19	22	258.664
#464	ZNF174	3	13	16	311.589
#465	TAL1	3	14	17	497.427
#466	BARX1	3	18	21	289.405
#467	ZFP36L1	3	17	20	362.041
#468	NRL	3	18	21	1198.332
#469	NFE2	3	14	17	1018.516
#470	POU1F1	3	19	22	734.357
#471	TSC22D3	3	14	17	242.836
#472	MLXIPL	3	14	17	217.661
#473	ZNF81	3	21	24	290.308
#474	GABPB1	3	20	23	230.496
#475	HOXC5	3	18	21	215.949
#476	PPARG	3	21	24	270.763
#477	IRX5	2	20	22	214.275
#478	SOX21	2	18	20	773.808
#479	TBX2	2	20	22	477.244
#480	BLZF1	2	15	17	237.625
#481	RBPJL	2	20	22	327.913
#482	PHOX2A	2	21	23	385.732
#483	ALX3	2	10	12	267.714
#484	ESR2	2	16	18	241.937
#485	HNF1B	2	17	19	140.557
#486	ZIC1	2	26	28	418.677
#487	SIM1	2	23	25	236.004
#488	CREB5	2	21	23	106.144
#489	ZNF157	2	21	23	432.544
#490	FUBP1	2	19	21	155.459
#491	MEOX1	2	20	22	188.52
#492	PITX1	1	27	28	153.653
#493	CRX	1	15	16	60.439
#494	FOXD1	1	19	20	129.156
#495	HOXD13	1	21	22	224.834
#496	RUNX2	1	17	18	222.989
#497	E2F2	1	12	13	99.182
#498	TLX3	1	21	22	59.664
#499	STRN3	0	27	27	0
#500	GATA3	0	17	17	0