Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	CEBPE	48	4	52	13655.909
#2	GLI3	39	4	43	15014.369
#3	FEV	38	1	39	38.071
#4	OLIG2	36	3	39	738.402
#5	CNOT8	36	6	42	1224.876
#6	LMX1B	33	5	38	1464.526
#7	PRDM1	31	8	39	1005.793
#8	ETV4	30	8	38	2334.341
#9	GATA1	28	4	32	2085.94
#10	HNF4A	28	5	33	191.203
#11	TCF15	28	7	35	3380.078
#12	TBX5	27	5	32	316.077
#13	HOXD13	26	10	36	1146.27
#14	TFAP2B	26	3	29	104.614
#15	SCAND2	26	6	32	431.622
#16	POU6F1	25	7	32	584.886
#17	ZNF207	25	7	32	826.701
#18	MEF2C	25	8	33	1217.479
#19	RXRG	25	9	34	2809.836
#20	TAF5	24	7	31	5425.974
#21	NFE2L2	24	6	30	732.61
#22	VAV1	24	6	30	990.641
#23	NFIL3	24	4	28	389.374
#24	GTF2H2	24	10	34	3543.794
#25	UBN1	23	9	32	1026.663
#26	SP3	23	10	33	1212.623
#27	NFAT5	23	11	34	2099.716
#28	MZF1	23	2	25	112.737
#29	STAT4	22	6	28	456.473
#30	ELF5	22	3	25	924.946
#31	ADNP	22	9	31	1867.114
#32	ZNF91	22	8	30	880.721
#33	GBX2	21	11	32	2726.016
#34	ZSCAN12	21	4	25	326.218
#35	ZEB1	21	16	37	5042.203
#36	TSC22D4	21	14	35	5098.555
#37	NR1H2	21	7	28	4522.153
#38	MYF6	21	3	24	954.126
#39	CREM	21	7	28	1036.58
#40	HESX1	21	5	26	599.497
#41	RORC	20	8	28	2572.253
#42	ZNF217	20	10	30	3682.127
#43	MYCL2	20	11	31	1694.941
#44	NOLC1	20	5	25	235.976
#45	BHLHE40	20	6	26	1233.426
#46	RORA	20	12	32	1023.564
#47	ONECUT2	20	15	35	1870.67
#48	HOXA11	19	7	26	344.078
#49	POU4F2	19	8	27	3363.103
#50	NFYC	19	4	23	320.283
#51	CREBBP	19	5	24	1565.896
#52	MAF	19	4	23	1177.127
#53	FOXJ3	18	7	25	1129.121
#54	NFKB1	18	8	26	1364.28
#55	NFIX	18	6	24	529.502
#56	NR1I3	18	6	24	4230.363
#57	HNF4G	18	3	21	493.281
#58	FOS	18	8	26	8081.83
#59	ARNT	18	8	26	917.099
#60	MITF	18	7	25	4274.947
#61	HINFP	18	6	24	1572.588
#62	TFEB	18	3	21	699.809
#63	ZEB2	18	10	28	1035.049
#64	SPDEF	17	7	24	244.291
#65	YY1	17	8	25	942.764
#66	PHOX2B	17	11	28	401.901
#67	POU2F1	17	1	18	47.191
#68	NR1I2	16	11	27	4659.312
#69	RUNX1	16	11	27	1178.177
#70	JUND	16	9	25	1651.304
#71	RFXANK	16	6	22	370.753
#72	ZNF175	16	6	22	1393.625
#73	TRIM28	16	8	24	2749.014
#74	SMAD4	16	10	26	1152.396
#75	HOXD10	16	6	22	3493.721
#76	ELF4	16	8	24	1903.537
#77	STAT5B	16	9	25	1470.887
#78	CNBP	16	9	25	3588.696
#79	HOXA1	16	7	23	823.473
#80	NR2E3	15	8	23	3183.286
#81	RUNX2	15	4	19	1036.256
#82	IKZF1	15	10	25	426.951
#83	POU1F1	15	8	23	1973.66
#84	POU2F2	15	5	20	716.964
#85	HNRNPK	15	9	24	862.983
#86	SALL2	15	10	25	1940.917
#87	RBPJ	15	7	22	236.707
#88	HCFC1	15	7	22	1084.461
#89	RUNX1T1	15	11	26	2668.083
#90	CLOCK	15	4	19	3288.809
#91	ZNF192	15	8	23	597.645
#92	RCOR1	15	6	21	943.136
#93	FOXA2	15	6	21	568.691
#94	DLX4	15	2	17	1236.206
#95	RCAN1	14	11	25	2726.108
#96	MYT1	14	5	19	1235.055
#97	RFX3	14	15	29	2645.724
#98	MEIS1	14	9	23	1509.627
#99	TEAD1	14	11	25	1402.502
#100	CREB5	14	11	25	2053.464
#101	TBX1	14	5	19	205.842
#102	ETV6	14	7	21	659.103
#103	NR2F2	14	10	24	903.108
#104	CTCF	14	6	20	769.528
#105	ERF	14	8	22	700.856
#106	TCF4	14	9	23	1637.734
#107	ZNF41	14	6	20	13357.868
#108	IRX5	14	7	21	814.158
#109	TFAP4	14	7	21	836.82
#110	LZTR1	13	7	20	1354.771
#111	MYOD1	13	7	20	685.065
#112	ZNF263	13	9	22	2512.998
#113	ETV1	13	11	24	5071.602
#114	CEBPD	13	9	22	3208.241
#115	BRD8	13	14	27	868.499
#116	HDAC2	13	6	19	775.377
#117	MAFF	13	7	20	789.304
#118	FOXI1	13	7	20	860.762
#119	ZNF24	13	9	22	742.17
#120	ZNF35	13	10	23	2606.667
#121	PPARG	13	3	16	428.624
#122	MEF2A	13	7	20	695.759
#123	KLF10	12	7	19	716.19
#124	TAL1	12	8	20	613.465
#125	PAX6	12	11	23	586.662
#126	MECOM	12	13	25	1572.586
#127	SOX12	12	5	17	211.68
#128	HCLS1	12	9	21	1467.221
#129	NR0B1	12	10	22	4226.632
#130	NPAT	12	10	22	4764.184
#131	KLF9	12	7	19	1329.221
#132	CITED2	12	13	25	1599.298
#133	GLI2	12	15	27	1987.276
#134	TBX19	12	9	21	366.044
#135	PITX2	12	8	20	2011.589
#136	ZFP37	12	10	22	1389.459
#137	NEUROD2	12	7	19	1158.651
#138	HOPX	12	15	27	2569.352
#139	SOX30	12	12	24	2883.877
#140	HMGB2	12	8	20	1270.339
#141	SATB2	12	12	24	1285.481
#142	TAF12	12	15	27	2056.795
#143	BCL6	12	10	22	1305.969
#144	NFYB	12	8	20	1102.706
#145	GATA3	12	7	19	1363.413
#146	KLF7	11	8	19	2486.58
#147	JUNB	11	11	22	1017.431
#148	BNC1	11	17	28	5773.451
#149	FOXE1	11	14	25	1985.054
#150	MYC	11	17	28	3255.395
#151	NR2F6	11	11	22	1102.205
#152	HSF2	11	7	18	1878.08
#153	HOXB5	11	5	16	963.025
#154	HOXA2	11	11	22	685.306
#155	STAT3	11	8	19	1043.241
#156	ZNF500	11	5	16	481.706
#157	ELK1	11	8	19	857.363
#158	CBFB	11	8	19	1100.723
#159	HMGA2	11	7	18	615.688
#160	TAF1B	11	10	21	2802.936
#161	TCF3	11	10	21	2491.328
#162	MLLT10	11	6	17	3490.476
#163	ZNF132	11	10	21	1896.554
#164	FOXK2	11	10	21	18969.724
#165	NKX3-2	11	6	17	257.425
#166	MAFK	11	8	19	2103.004
#167	ASCL2	11	7	18	425.857
#168	ELF2	11	8	19	249.437
#169	ATF3	11	6	17	725.09
#170	NR2C1	11	9	20	1028.803
#171	ZNF117	11	9	20	1475.276
#172	AFF1	11	9	20	3223.296
#173	HOXC11	11	5	16	806.17
#174	PA2G4	10	10	20	1589.454
#175	MYCL1	10	8	18	816.185
#176	ZNF92	10	10	20	1330.068
#177	RB1	10	8	18	2170.949
#178	MSC	10	5	15	402.814
#179	VDR	10	16	26	2174.065
#180	PLSCR1	10	5	15	366.62
#181	LHX2	10	15	25	2076.873
#182	FOXJ2	10	9	19	2158.322
#183	NRL	10	11	21	4872.397
#184	NFE2L1	10	4	14	169.661
#185	CRX	10	8	18	215.877
#186	ZNF3	10	7	17	1126.454
#187	AHR	10	9	19	1393.172
#188	ELF3	10	14	24	2208.239
#189	PITX3	10	7	17	384.195
#190	PPBPL2	10	12	22	1415.296
#191	ZNF268	10	10	20	1700.567
#192	CTBP1	10	6	16	676.588
#193	ALX1	10	6	16	529.364
#194	BACH1	10	11	21	1109.511
#195	PTH	10	13	23	2630.965
#196	KDM5A	10	11	21	7344.634
#197	SNAI2	10	14	24	915.351
#198	TCF12	10	9	19	466.372
#199	E2F2	10	8	18	1510.271
#200	MTA1	10	15	25	3150.35
#201	TCF21	9	11	20	1825.02
#202	TGIF2	9	7	16	942.861
#203	NR3C1	9	9	18	1055.727
#204	LMO4	9	10	19	1433.698
#205	E2F1	9	6	15	365.225
#206	SPEN	9	8	17	963.611
#207	NFKB2	9	10	19	730.708
#208	AEBP1	9	10	19	2671.476
#209	GABPB1	9	10	19	2551.135
#210	T	9	12	21	1160.584
#211	ALX3	9	8	17	488.983
#212	XBP1	9	9	18	1038.449
#213	IRF2	9	8	17	612.81
#214	ELK4	9	8	17	1203.931
#215	HIF1A	9	9	18	687.781
#216	NEUROD1	9	8	17	1890.183
#217	LHX1	9	10	19	1617.499
#218	MYCN	9	6	15	1622.619
#219	E2F5	9	9	18	1856.734
#220	NFATC3	9	13	22	2454.258
#221	SMAD9	9	10	19	1605.967
#222	HOXB1	9	6	15	266.717
#223	JUN	9	9	18	1589.558
#224	CSRNP2	8	6	14	737.76
#225	ASCL1	8	9	17	1287.665
#226	ONECUT1	8	13	21	4951.132
#227	FOXD1	8	8	16	563.995
#228	SIM1	8	13	21	724.687
#229	KLF4	8	9	17	2109.443
#230	FOSB	8	5	13	614.509
#231	CEBPB	8	8	16	1345.716
#232	RERE	8	10	18	1603.372
#233	NFATC4	8	10	18	534.047
#234	IRF1	8	6	14	334.299
#235	ENO1	8	7	15	898.877
#236	KLF11	8	9	17	436.647
#237	RELA	8	15	23	2917.554
#238	SMAD5	8	10	18	2090.179
#239	TBR1	8	5	13	394.559
#240	SRY	8	12	20	1749.794
#241	FOXN1	8	10	18	587.327
#242	ETV2	8	10	18	1654.248
#243	ETS2	8	9	17	756.661
#244	TRIM22	8	21	29	1779.745
#245	FOXO1	8	10	18	827.744
#246	TFAP2A	8	16	24	1935.307
#247	FOXC1	8	10	18	2253.845
#248	SMAD6	8	5	13	1088.832
#249	PCGF2	8	12	20	1393.816
#250	KLF1	8	5	13	179.699
#251	ZNF238	8	5	13	1581.957
#252	NFE2	8	5	13	548.437
#253	TCFL5	8	9	17	985.62
#254	ZNF148	8	11	19	510.363
#255	TWIST1	8	11	19	2397.101
#256	SOX13	8	13	21	1461.666
#257	NFIC	8	8	16	4705.544
#258	SMAD1	8	11	19	2167.716
#259	TFAM	8	8	16	329.246
#260	MEIS2	8	5	13	1226.205
#261	CREB1	8	12	20	1001.879
#262	PLAGL2	8	10	18	929.2
#263	POU3F2	8	7	15	877.457
#264	SOX9	8	10	18	898.203
#265	ZNF81	8	15	23	2771.812
#266	PEG3	8	10	18	1244.445
#267	NPAS2	8	6	14	303.896
#268	NFIB	7	8	15	716.497
#269	PRDM2	7	9	16	443.646
#270	LEF1	7	14	21	2068.927
#271	PAX5	7	11	18	1417.388
#272	ISL1	7	12	19	2379.289
#273	DLX2	7	7	14	2300.018
#274	HES1	7	7	14	342.684
#275	ZNF154	7	16	23	4620.21
#276	HMG20B	7	7	14	323.673
#277	PRRX1	7	14	21	1356.838
#278	CBL	7	9	16	769.037
#279	TFDP1	7	10	17	660.068
#280	TAF7	7	13	20	1252.486
#281	RBCK1	7	10	17	903.503
#282	TFE3	7	8	15	1332.95
#283	PITX1	7	12	19	1538.665
#284	HNF1A	7	8	15	249.819
#285	RARB	7	10	17	2751.762
#286	CBFA2T3	7	1	8	68.713
#287	DMTF1	7	9	16	7941.934
#288	LASS6	7	11	18	1579.416
#289	EGR2	7	7	14	810.794
#290	EGR3	7	10	17	848.695
#291	TLX1	7	5	12	249.002
#292	PTTG1	7	11	18	1751.371
#293	ZHX2	7	10	17	1690.854
#294	ESR2	7	8	15	2370.919
#295	TLX2	7	9	16	15214.353
#296	E2F3	7	12	19	598.142
#297	RXRB	7	6	13	294.095
#298	SOX21	7	8	15	4041.051
#299	BUD31	7	11	18	1278.76
#300	TFDP2	7	10	17	1033.075
#301	SALL1	7	14	21	2079.299
#302	MAX	7	11	18	636.825
#303	REST	7	13	20	671.325
#304	TCF25	7	9	16	944.422
#305	HSF4	7	9	16	642.079
#306	HOXD9	7	8	15	888.397
#307	CREB3L2	7	10	17	870.461
#308	HSF1	7	12	19	1486.357
#309	PBX3	7	10	17	992.356
#310	NR1H4	7	10	17	1760.155
#311	IRF7	7	14	21	2458.13
#312	ZNF135	6	8	14	636.628
#313	SLC26A3	6	13	19	601.043
#314	NR4A3	6	9	15	736.403
#315	RUNX3	6	14	20	1623.314
#316	ESR1	6	15	21	962.359
#317	TAF4B	6	7	13	803.079
#318	PURA	6	6	12	276.72
#319	TCF7L2	6	10	16	1184.721
#320	ST18	6	11	17	1238.742
#321	TRIM29	6	17	23	2954.164
#322	TSC22D3	6	8	14	538.544
#323	STRN3	6	10	16	281.357
#324	HNF1B	6	8	14	861.076
#325	SMAD2	6	8	14	255.726
#326	WT1	6	9	15	1719.985
#327	ETV5	6	7	13	1367.384
#328	SUPT6H	6	12	18	259.684
#329	ZNF45	6	9	15	1302.282
#330	PAX8	6	13	19	652.172
#331	FOXF2	6	5	11	271.447
#332	PDX1	6	7	13	834.896
#333	ATF5	6	9	15	899.474
#334	NR2C2	6	7	13	3124.068
#335	PBX1	6	9	15	771.757
#336	POU6F2	6	11	17	829.344
#337	ZNF131	6	14	20	1011.444
#338	ZBTB25	6	10	16	1303.704
#339	ELF1	6	14	20	410.158
#340	NFX1	6	10	16	685.379
#341	ZNF189	6	12	18	1079.552
#342	ZKSCAN4	6	10	16	1875.554
#343	HDAC1	6	10	16	495.14
#344	ZNF193	6	11	17	1407.488
#345	ZHX3	6	7	13	3983.856
#346	HOXC4	6	10	16	1827.547
#347	NFATC1	5	16	21	1232.926
#348	MTF1	5	13	18	759.291
#349	ADNP2	5	9	14	576.848
#350	GCM1	5	7	12	509.039
#351	HLF	5	8	13	3871.26
#352	TBX2	5	9	14	740.693
#353	RORB	5	12	17	4558.514
#354	HOXD4	5	6	11	1409.159
#355	CIR1	5	8	13	593.303
#356	MYBL2	5	10	15	530.777
#357	SOX5	5	19	24	2681.988
#358	SMAD3	5	7	12	4987.481
#359	POU3F4	5	10	15	1354.419
#360	PAX3	5	17	22	1711.553
#361	ATF2	5	11	16	1154.309
#362	SIM2	5	17	22	11939.585
#363	HMGA1	5	5	10	330.449
#364	MEIS3P1	5	7	12	1632.362
#365	FOXO3	5	10	15	461.193
#366	MYT1L	5	9	14	747.469
#367	TSC22D1	5	10	15	534.182
#368	ZFHX3	5	9	14	1599.376
#369	MSX1	5	12	17	1476.151
#370	HNRNPAB	5	6	11	209.09
#371	NR1D2	5	9	14	290.608
#372	TP63	5	9	14	326.111
#373	HHEX	5	18	23	949.437
#374	PAX4	5	8	13	709.055
#375	NR4A1	5	9	14	1115.161
#376	ZNF85	5	9	14	348.497
#377	CREBL2	5	12	17	2090.684
#378	NR6A1	5	4	9	90.983
#379	POU4F1	5	11	16	4393.603
#380	TGIF1	5	14	19	816.263
#381	ATF4	5	14	19	1372.525
#382	SP1	4	9	13	531.797
#383	WNT5A	4	14	18	856.75
#384	BATF	4	7	11	239.929
#385	NKX2-1	4	7	11	742.093
#386	ZIC2	4	6	10	1238.725
#387	SOX15	4	6	10	183.541
#388	ATF6B	4	5	9	129.317
#389	ZNF140	4	11	15	1202.157
#390	KLF12	4	11	15	592.596
#391	ZNF167	4	11	15	3085.786
#392	ETS1	4	8	12	232.61
#393	CSDA	4	9	13	315.904
#394	REL	4	11	15	1874.932
#395	HOXD8	4	11	15	2625.905
#396	TBX10	4	8	12	389.575
#397	FUBP1	4	10	14	1609.375
#398	EGR1	4	12	16	792.36
#399	FOXN3	4	9	13	888.354
#400	BTG2	4	5	9	250.163
#401	SOX4	4	14	18	1428.487
#402	ZNF197	4	13	17	1103.103
#403	POU2F3	4	10	14	1784.533
#404	FOXA1	4	16	20	2534.033
#405	USF2	4	9	13	834.603
#406	SCML2	4	9	13	297.167
#407	ATF1	4	8	12	643.538
#408	DDIT3	4	7	11	131.553
#409	HOXD1	4	18	22	5956.805
#410	SHOX	4	12	16	2390.821
#411	TCEAL1	4	13	17	2025.125
#412	PPARA	4	11	15	389.223
#413	ARID4A	4	12	16	1646.14
#414	ARNTL	4	13	17	333.668
#415	GTF2H4	4	11	15	1954.91
#416	CUX2	4	16	20	1212.869
#417	IRF9	4	6	10	276.378
#418	TADA2A	4	11	15	549.455
#419	GATA2	3	19	22	1425.332
#420	KLF6	3	10	13	810.448
#421	SATB1	3	12	15	470.741
#422	NR1H3	3	9	12	334.412
#423	ZFP36L2	3	13	16	888.225
#424	TFAP2C	3	8	11	803.867
#425	ARNT2	3	13	16	5031.627
#426	GBX1	3	8	11	186.239
#427	TFCP2	3	10	13	264.593
#428	STAT1	3	17	20	2000.958
#429	SOX11	3	13	16	1728.222
#430	HR	3	5	8	176.962
#431	RNF4	3	8	11	452.043
#432	HOXA10	3	9	12	275.69
#433	HMX1	3	11	14	830.931
#434	CITED1	3	6	9	235.32
#435	PGR	3	12	15	1708.56
#436	ERG	3	15	18	839.008
#437	CUX1	3	12	15	993.112
#438	ZNF643	3	16	19	425.878
#439	ATF7	3	12	15	825.298
#440	NME2	3	6	9	170.265
#441	SP4	3	14	17	663.447
#442	NR5A2	3	12	15	614.092
#443	PBX2	3	12	15	4132.211
#444	FLI1	3	7	10	228.97
#445	NR2E1	3	15	18	3625.369
#446	MEOX1	3	11	14	628.589
#447	SIX1	3	11	14	523.447
#448	SLC30A9	3	9	12	158.092
#449	GATAD1	3	8	11	712.284
#450	GABPA	3	5	8	363.53
#451	HOXD3	3	9	12	1212.548
#452	HIRA	3	9	12	76.173
#453	TCF20	2	14	16	310.433
#454	STAT5A	2	9	11	109.166
#455	CTNNB1	2	9	11	61.827
#456	THRB	2	10	12	170.063
#457	TEAD4	2	12	14	400.846
#458	PKNOX1	2	14	16	511.852
#459	NR4A2	2	15	17	302.473
#460	TCF7	2	14	16	1086.004
#461	EPAS1	2	16	18	3026.24
#462	TSC22D2	2	7	9	377.739
#463	TP53	2	11	13	298.623
#464	FOXG1	2	10	12	476.239
#465	MSX2	2	13	15	1351.667
#466	ZNF274	2	11	13	1091.585
#467	ZNF75D	2	13	15	835.445
#468	IRF4	2	16	18	900.097
#469	E2F4	2	12	14	1098.612
#470	ZIC3	2	8	10	175.862
#471	NFYA	2	9	11	287.348
#472	PLAG1	2	20	22	336.784
#473	NR2F1	2	16	18	2057.332
#474	SOLH	2	12	14	286.319
#475	FOXF1	2	13	15	317.659
#476	SOX2	2	12	14	2107.947
#477	CREBZF	2	10	12	282.849
#478	HOXA5	2	19	21	2415.033
#479	ZNF165	2	11	13	65.982
#480	GATA6	1	12	13	285.567
#481	HOXB2	1	13	14	737.693
#482	NFE2L3	1	10	11	332.548
#483	MEOX2	1	18	19	52.266
#484	ZIC1	1	19	20	1410.793
#485	ESRRG	1	11	12	33.715
#486	PHTF1	1	17	18	1465.634
#487	HOXA9	1	10	11	739.997
#488	SNAPC4	1	11	12	201.451
#489	C11orf9	1	13	14	994.129
#490	RFXAP	1	15	16	87.032
#491	NKX3-1	1	6	7	83.059
#492	ZNF33B	1	9	10	71.903
#493	KLF5	1	12	13	51.978
#494	MYF5	1	19	20	1897.351
#495	AR	1	13	14	183.774
#496	GAS7	1	10	11	216.106
#497	TAF13	0	15	15	0
#498	SOX1	0	10	10	0
#499	HOXA4	0	16	16	0
#500	CDKN2A	0	20	20	0