Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SNAI2	83	0	83	0
#2	HLF	74	1	75	13.457
#3	BNC1	62	6	68	2618.239
#4	CEBPB	62	9	71	546.078
#5	GAS7	60	6	66	592.124
#6	KLF7	60	2	62	17.639
#7	ELF4	59	5	64	719.928
#8	PITX1	56	4	60	73.481
#9	GRHL3	56	0	56	0
#10	NFIA	55	10	65	995.438
#11	HOPX	55	5	60	1012.545
#12	PBX1	55	5	60	490.537
#13	EBF1	54	4	58	92.912
#14	ZNF238	47	9	56	2102.658
#15	LMO4	47	9	56	2503.706
#16	RELB	45	4	49	728.86
#17	TP63	43	8	51	2780.293
#18	SMAD9	43	3	46	572.002
#19	NOLC1	42	5	47	1558.234
#20	NFE2L2	42	10	52	2341.999
#21	EHF	41	9	50	1188.025
#22	IKZF1	41	0	41	0
#23	HMGA2	40	10	50	475.803
#24	TSHZ3	40	8	48	385.424
#25	HCLS1	40	2	42	1196.244
#26	NR2F2	39	8	47	197.621
#27	UHRF1	39	9	48	425.663
#28	KLF10	39	8	47	212.209
#29	NFIL3	39	6	45	190.071
#30	RUNX2	38	10	48	1475.145
#31	TRIM29	38	4	42	1085.836
#32	SOX2	38	10	48	1147.722
#33	RFX5	37	8	45	981.643
#34	FOSL1	37	13	50	395.391
#35	OVOL1	36	7	43	326.588
#36	MTF1	36	4	40	64.827
#37	GABPB1	36	6	42	621.918
#38	TEAD2	35	11	46	6079.638
#39	NR3C2	35	11	46	1477.582
#40	AEBP1	35	5	40	172.564
#41	MEOX2	34	5	39	2186.253
#42	MLLT10	34	12	46	7292.549
#43	SOX15	34	10	44	3422.243
#44	MXD1	33	13	46	555.085
#45	STAT5B	33	6	39	1798.13
#46	ZNF367	33	4	37	6718.192
#47	KDM5B	33	11	44	4767.925
#48	FUBP1	33	6	39	824.475
#49	NFAT5	33	9	42	368.76
#50	ZHX1	32	9	41	1772.839
#51	SPIB	32	9	41	3668.428
#52	NPAT	31	10	41	2094.869
#53	KDM5A	31	6	37	354.017
#54	ETS1	30	13	43	3123.077
#55	NFIB	30	13	43	3749.323
#56	ZNF33A	30	13	43	5137.708
#57	E2F3	29	13	42	4098.711
#58	RARG	29	7	36	1675.218
#59	IRF8	29	2	31	14.676
#60	FOXK2	29	6	35	893.795
#61	MEIS2	29	10	39	2634.158
#62	TEAD4	29	12	41	563.236
#63	RUNX1T1	29	6	35	626.154
#64	IRF6	29	9	38	515.551
#65	MITF	29	14	43	2025.76
#66	SOX4	29	13	42	2430.717
#67	LASS2	28	13	41	1667.628
#68	SP4	28	9	37	1050.67
#69	SPEN	28	6	34	104.549
#70	SATB1	28	17	45	1356.279
#71	NANOGNB	28	4	32	1644.118
#72	E2F7	28	3	31	48.113
#73	ETS2	28	11	39	977.8
#74	NFIC	27	10	37	1053.171
#75	ZNF397	27	13	40	1621.412
#76	MYPOP	27	10	37	653.252
#77	STAT1	27	6	33	1825.613
#78	TWIST1	27	5	32	796.436
#79	SP140	26	3	29	21.996
#80	ENO1	26	16	42	1965.423
#81	ZNF281	26	15	41	3364.257
#82	SMAD5	26	14	40	1123.173
#83	C5orf41	26	14	40	7682.125
#84	GLIS3	25	8	33	965.859
#85	RUNX3	25	7	32	519.451
#86	RORA	25	16	41	1866.509
#87	HEYL	25	9	34	172.64
#88	CBL	24	7	31	360.164
#89	RUNX1	24	7	31	509.587
#90	NFKB2	24	14	38	6133.889
#91	KLF5	24	6	30	1659.495
#92	GLI3	24	16	40	9663.787
#93	KLF3	23	9	32	2476.807
#94	ZSCAN18	23	15	38	1873.503
#95	CREB3L4	23	7	30	1827.587
#96	ELF3	23	13	36	931.446
#97	ETV6	23	12	35	1618.968
#98	NFIX	23	12	35	4323.156
#99	RERE	23	11	34	330.498
#100	ARNT2	23	13	36	2214.018
#101	MEIS1	23	11	34	452.227
#102	MEF2C	23	10	33	460.248
#103	DRAP1	22	7	29	1822.293
#104	HEY1	22	14	36	1327.522
#105	LHX2	22	19	41	3265.025
#106	MYC	22	7	29	1001.837
#107	CCRN4L	22	9	31	2058.618
#108	HMGB2	21	10	31	2748.428
#109	ZSCAN16	21	13	34	586.813
#110	LASS6	21	18	39	1765.066
#111	MSX2	21	14	35	1812.39
#112	SIM2	21	13	34	499.664
#113	PRRX1	20	13	33	1355.243
#114	RBPJ	20	8	28	2505.283
#115	ATF2	20	3	23	83.902
#116	HIF1A	20	12	32	253.037
#117	HOXC13	20	13	33	1698.301
#118	TFEC	20	8	28	2851.09
#119	FOXM1	20	13	33	1809.817
#120	DLX1	20	9	29	1362.01
#121	TFAP2A	19	15	34	2939.866
#122	DLX3	19	10	29	2080.172
#123	TCF7	19	11	30	1566.772
#124	VAV1	19	6	25	626.864
#125	TRIM22	19	4	23	1720.5
#126	ZEB1	19	17	36	1878.203
#127	ELK1	19	8	27	3223.185
#128	TCF4	19	12	31	794.926
#129	REL	19	11	30	980.437
#130	SIX4	19	14	33	1695.607
#131	RCOR1	18	10	28	1559.202
#132	PURB	18	19	37	423.144
#133	POU2F2	18	10	28	820.373
#134	NR2F1	18	14	32	305.352
#135	GTF2IRD1	18	10	28	989.117
#136	CREB3L1	18	12	30	1850.599
#137	MAFB	18	16	34	2125.16
#138	NFE2L1	18	10	28	453.257
#139	FOSL2	18	18	36	2420.724
#140	ELF1	18	10	28	1236.787
#141	RBCK1	18	15	33	1817.708
#142	FOXP2	17	15	32	1082.063
#143	MSRB2	17	23	40	3002.182
#144	DLX2	17	12	29	1649.757
#145	IRF4	17	5	22	45.481
#146	BHLHE41	17	18	35	2480.58
#147	LEF1	17	11	28	2182.283
#148	ARNTL	17	10	27	1540.049
#149	KLF12	17	8	25	599.18
#150	CREM	17	17	34	723.417
#151	CEBPA	17	11	28	1397.497
#152	PITX2	17	16	33	1470.048
#153	SP1	17	7	24	1357.71
#154	PTTG1	17	13	30	3134.241
#155	RELA	16	15	31	3320.836
#156	CREB1	16	6	22	368.22
#157	NFE2L3	16	18	34	3526.857
#158	BACH2	16	9	25	810.398
#159	MECOM	16	11	27	2113.719
#160	MTA3	16	16	32	852.617
#161	SOX30	16	13	29	6440.648
#162	SMAD4	16	11	27	3437.311
#163	FOXE1	16	18	34	704.273
#164	GTF2I	16	8	24	432.538
#165	MLL	16	9	25	479.177
#166	SREBF2	15	8	23	393.73
#167	E2F6	15	14	29	1750.817
#168	FOS	15	4	19	317.325
#169	CBFB	15	8	23	4967.02
#170	TEAD1	15	10	25	158.871
#171	PRDM1	15	14	29	2726.812
#172	MMP14	15	13	28	5252.976
#173	ERF	15	15	30	244.188
#174	ATF1	15	13	28	3155.981
#175	KLF2	15	15	30	4689.11
#176	MSX1	15	18	33	7356.574
#177	KLF9	14	10	24	2342.056
#178	ZNF148	14	15	29	1193.516
#179	NKX3-1	14	3	17	20.482
#180	IRF9	14	7	21	1574.075
#181	HMG20B	14	18	32	2038.106
#182	MEIS3P1	14	18	32	881.61
#183	TAF13	14	15	29	1338.167
#184	ZFP42	14	16	30	9413.013
#185	ATF5	14	15	29	3691.639
#186	STAT2	14	11	25	3673.875
#187	TGIF2	14	17	31	653.334
#188	ZNF33B	14	18	32	2144.12
#189	BLZF1	14	18	32	1151.826
#190	TBX2	13	17	30	2229.616
#191	ZXDC	13	10	23	295.433
#192	TCF3	13	14	27	432.349
#193	ZNF91	13	17	30	1372.876
#194	BACH1	13	19	32	7857.933
#195	TSC22D2	13	16	29	1100.759
#196	NFATC3	13	8	21	364.492
#197	RCAN1	13	18	31	628.302
#198	PPARD	13	14	27	470.024
#199	PRRX2	13	17	30	1505.162
#200	TBX1	13	20	33	4195.627
#201	PURA	13	18	31	1796.431
#202	MZF1	13	16	29	504.352
#203	ZNF496	13	15	28	1922.688
#204	ZNF215	13	19	32	6600.643
#205	CLOCK	13	15	28	1495.248
#206	MYBL2	13	13	26	428.27
#207	TEAD3	13	7	20	531.14
#208	TSHZ2	13	12	25	493.714
#209	NKX2-3	13	20	33	2813.327
#210	HOXC9	12	18	30	1403.398
#211	YEATS4	12	12	24	2595.916
#212	HOXD10	12	18	30	621.792
#213	IRF7	12	8	20	842.814
#214	HOXD11	12	18	30	3773.951
#215	FLI1	12	14	26	5019.15
#216	TCF19	12	8	20	173.746
#217	PEG3	12	14	26	1497.613
#218	STAT4	12	9	21	288.368
#219	GABPA	12	14	26	1094.952
#220	FOSB	12	2	14	775.466
#221	TCFL5	12	15	27	1489.454
#222	ETV4	12	16	28	1430.147
#223	FOXA1	12	11	23	1157.525
#224	MGA	12	18	30	1706.38
#225	HHEX	11	9	20	1472.203
#226	ZHX3	11	19	30	7765.776
#227	BATF	11	10	21	1171.2
#228	CBFA2T2	11	12	23	1289.421
#229	MTA1	11	19	30	1560.699
#230	NOTCH1	11	20	31	1752.395
#231	FOXN2	11	21	32	608.174
#232	SIN3A	11	11	22	611.815
#233	CUX1	11	13	24	950.112
#234	ZFPM2	11	15	26	3010.285
#235	MEOX1	11	12	23	909.894
#236	JUNB	11	10	21	2644.009
#237	TFAM	11	14	25	1024.574
#238	TP73	11	17	28	2553.75
#239	L3MBTL4	11	16	27	2317.471
#240	HOXA10	11	20	31	1107.068
#241	EGR1	11	3	14	263.615
#242	NR2F6	11	11	22	438.117
#243	DLX6	11	21	32	2969.74
#244	ZKSCAN1	11	16	27	3857.001
#245	SATB2	11	13	24	1164.544
#246	IRX4	10	19	29	639.831
#247	FOXD1	10	16	26	3063.217
#248	LHX8	10	12	22	738.502
#249	E2F5	10	10	20	199.48
#250	HES1	10	17	27	1063.605
#251	ETV5	10	17	27	1668.207
#252	FOXF1	10	13	23	707.844
#253	MYCL1	10	17	27	714.599
#254	ZIC2	10	15	25	687.446
#255	SOX12	10	15	25	2197.144
#256	GLIS2	10	13	23	4356.308
#257	E2F8	10	17	27	730.396
#258	SPDEF	10	4	14	1910.479
#259	PLAG1	10	14	24	1172.766
#260	TSHZ1	10	11	21	237.28
#261	CDKN2A	10	18	28	1883.762
#262	KLF11	10	23	33	5106.869
#263	PCGF6	10	11	21	273.166
#264	TEF	10	13	23	4199.418
#265	XBP1	10	12	22	2939.511
#266	CEBPD	10	14	24	1866.059
#267	BATF3	10	13	23	1875.438
#268	TBX15	10	6	16	1294.555
#269	SREBF1	10	16	26	586.616
#270	ZEB2	10	14	24	771.531
#271	ZBTB38	9	19	28	1463.756
#272	GATA6	9	18	27	2565.104
#273	BHLHE40	9	18	27	1336.213
#274	ISL1	9	16	25	1776.074
#275	FOXP4	9	24	33	2683.005
#276	ZFHX3	9	21	30	2589.803
#277	ZNF93	9	19	28	1369.982
#278	ATF7	9	23	32	873.496
#279	ZFPM1	9	18	27	2269.497
#280	EN1	9	16	25	2544.417
#281	ATF3	9	8	17	1518.578
#282	FOXP1	9	14	23	2420.605
#283	IRF1	9	9	18	270.652
#284	DBP	9	15	24	106.815
#285	TRPS1	9	15	24	1415.826
#286	PHTF1	9	18	27	1951.703
#287	CITED2	9	13	22	737.894
#288	HMGA1	9	19	28	1159.637
#289	ELK3	9	19	28	1041.015
#290	SOX11	9	13	22	244.792
#291	ZKSCAN5	9	13	22	1245.991
#292	PGBD1	9	21	30	2581.069
#293	KLF15	9	18	27	2528.861
#294	ZC3H8	9	19	28	654.589
#295	GTF2H4	9	11	20	2082.531
#296	ALS2CR8	9	16	25	1518.393
#297	AHR	9	16	25	674.737
#298	HR	9	19	28	637.363
#299	TWIST2	9	18	27	430.367
#300	NR4A1	9	6	15	1949.744
#301	GCFC1	9	15	24	992.166
#302	ESRRG	9	13	22	1482.308
#303	POU3F1	9	14	23	219.068
#304	TARDBP	9	18	27	1781.18
#305	SOLH	9	15	24	618.489
#306	E2F2	9	13	22	425.627
#307	GATAD2A	8	17	25	885.787
#308	TFEB	8	20	28	673.85
#309	MYF5	8	14	22	3434.899
#310	RARB	8	14	22	930.562
#311	SALL2	8	19	27	1159.151
#312	NPAS2	8	16	24	666.103
#313	GLI2	8	17	25	1003.697
#314	TSC22D3	8	13	21	654.131
#315	ETV1	8	14	22	1506.669
#316	ZFP36L2	8	18	26	748.51
#317	SIX1	8	15	23	1599.975
#318	BCL11B	8	18	26	538.699
#319	RB1	8	13	21	160.674
#320	PRDM2	8	12	20	397.934
#321	FOXC2	8	18	26	223.254
#322	MSC	8	22	30	510.687
#323	MAFF	8	10	18	212.316
#324	FOXO6	8	14	22	868.578
#325	ZFHX4	8	16	24	1951.117
#326	BTG2	8	10	18	1929.073
#327	CNOT7	8	13	21	628.934
#328	SLC2A4RG	8	14	22	901.999
#329	IRX1	8	23	31	939.15
#330	HMBOX1	8	16	24	522.996
#331	ZNF207	8	16	24	998.645
#332	BCL3	7	16	23	2470.152
#333	MYF6	7	9	16	1253.343
#334	GATA3	7	11	18	2536.574
#335	EOMES	7	10	17	94.553
#336	KLF4	7	15	22	853.09
#337	SOX7	7	18	25	901.899
#338	MAF	7	23	30	3332.775
#339	TGIF1	7	15	22	572.498
#340	JUN	7	20	27	1724.885
#341	ARNTL2	7	20	27	2409.326
#342	TP53	7	23	30	981.978
#343	SLC30A9	7	17	24	889.628
#344	EPAS1	7	14	21	230.308
#345	CTNNB1	7	18	25	1452.435
#346	TCF7L1	7	20	27	3103.652
#347	PLSCR1	7	12	19	3440.009
#348	TFAP2B	7	22	29	3425.654
#349	TFAP2C	7	17	24	878.543
#350	HOXD13	7	18	25	1410.635
#351	VDR	7	18	25	1305.525
#352	KLF6	7	13	20	1448.709
#353	CSRNP1	7	9	16	389.255
#354	TSC22D4	7	16	23	753.936
#355	PHF5A	7	14	21	4159.922
#356	GATA2	7	25	32	778.823
#357	ZNF277	7	15	22	2080.746
#358	NFX1	7	19	26	3052.746
#359	ZNF85	7	16	23	109.138
#360	RXRB	7	14	21	1028.439
#361	TULP4	7	14	21	962.574
#362	ZNF643	7	15	22	1003.737
#363	UBN1	7	12	19	690.45
#364	STRN3	6	25	31	756.693
#365	ATF6	6	17	23	150.545
#366	TFDP2	6	22	28	1129.27
#367	RORC	6	16	22	1645.953
#368	BATF2	6	10	16	335.255
#369	GTF2H2	6	13	19	269.535
#370	TFCP2L1	6	22	28	1016.514
#371	SOX13	6	20	26	1525.495
#372	C1orf85	6	14	20	280.899
#373	POU2F3	6	14	20	3391.603
#374	HOXA1	6	21	27	1999.852
#375	GRHL2	6	17	23	1310.869
#376	HOXC10	6	22	28	691.052
#377	TAF5	6	18	24	248.479
#378	IRX5	6	15	21	886.121
#379	PLAGL2	6	23	29	1067.251
#380	HOXA9	6	18	24	496.901
#381	HOXA5	6	23	29	1508.49
#382	CREB5	6	26	32	1514.438
#383	MBD1	6	18	24	1283.68
#384	PBX3	6	20	26	1198.46
#385	NR1D2	6	18	24	566.456
#386	HOXD8	6	21	27	1242.962
#387	SOX8	6	13	19	332.176
#388	POU2F1	6	18	24	319.686
#389	NFATC2	6	13	19	788.392
#390	ETV7	5	9	14	113.873
#391	FOXJ3	5	24	29	2219.268
#392	NFATC1	5	19	24	716.3
#393	ZSCAN21	5	18	23	2332.185
#394	HOXB2	5	17	22	376.205
#395	SIX2	5	26	31	2619.075
#396	ZNF3	5	16	21	1151.487
#397	ZNF92	5	22	27	492.064
#398	BCL6	5	21	26	279.307
#399	HOXB3	5	24	29	1506.289
#400	ESR1	5	14	19	2047.81
#401	RARA	5	21	26	7855.943
#402	RFXAP	5	24	29	2646.636
#403	FOXQ1	5	24	29	2176.198
#404	MEF2A	5	19	24	964.891
#405	LHX6	5	15	20	306.299
#406	ZNF639	5	24	29	536.599
#407	HEY2	5	20	25	319.463
#408	FOXF2	5	21	26	1028.788
#409	PAX8	5	15	20	1525.194
#410	TRERF1	5	25	30	281.983
#411	SOX9	5	21	26	1453.111
#412	SMAD6	4	15	19	839.075
#413	ZNF394	4	15	19	240.885
#414	POU4F1	4	14	18	804.865
#415	SOX10	4	13	17	181.339
#416	NFYA	4	22	26	514.71
#417	STAT6	4	18	22	324.199
#418	HOXA7	4	17	21	587.28
#419	PBX4	4	16	20	173.196
#420	TCF7L2	4	23	27	1648.274
#421	RORB	4	17	21	599.44
#422	CREBZF	4	15	19	1311.91
#423	IRX3	4	17	21	1619.829
#424	ZNF133	4	14	18	1563.369
#425	MYCN	4	15	19	1275.422
#426	NR4A2	4	9	13	949.822
#427	FOXC1	4	19	23	750.435
#428	SCAND3	4	18	22	5108.282
#429	DMRT2	4	20	24	611.916
#430	TCF15	4	24	28	2731.57
#431	ZNF83	4	21	25	2345.992
#432	ZNF187	4	18	22	440.777
#433	ZNF323	4	26	30	901.388
#434	NR4A3	4	16	20	1549.772
#435	CREB3	4	21	25	654.616
#436	SMAD1	4	28	32	1975.394
#437	PPARG	3	19	22	1984.751
#438	IRX2	3	29	32	461.238
#439	THRB	3	19	22	1337.577
#440	WNT5A	3	26	29	512.233
#441	RXRA	3	19	22	388.471
#442	JDP2	3	21	24	633.463
#443	ZFP90	3	19	22	265.923
#444	STAT3	3	20	23	347.924
#445	TFDP1	3	19	22	197.945
#446	FOXG1	3	21	24	373.568
#447	ARNT	3	17	20	1384.1
#448	ZNF165	3	19	22	756.352
#449	JUND	3	14	17	899.395
#450	ZNF449	3	20	23	968.624
#451	FBXW7	3	24	27	1221.849
#452	AFF4	3	19	22	156.42
#453	ZNF138	3	15	18	1628.3
#454	PBX2	3	20	23	318.073
#455	SMAD3	3	24	27	984.677
#456	CREB3L2	3	12	15	686.91
#457	FOXN3	3	16	19	156.705
#458	ZNF70	3	20	23	953.925
#459	HOXB7	3	20	23	110.81
#460	CSRNP3	2	19	21	870.953
#461	ZNF232	2	23	25	479.138
#462	ERG	2	22	24	259.476
#463	SCML1	2	23	25	897.036
#464	ELF5	2	26	28	147.146
#465	PAX6	2	25	27	268.868
#466	ZNF131	2	22	24	2323.698
#467	HOXC4	2	22	24	119.559
#468	PAX3	2	23	25	117.497
#469	HES5	2	15	17	115.192
#470	ETV3	2	23	25	208.235
#471	PPARA	2	22	24	1112.961
#472	MAFG	2	21	23	1033.34
#473	NR1H3	2	12	14	41.356
#474	ZBTB48	2	20	22	240.661
#475	ZNF24	2	19	21	648.596
#476	DLX4	2	24	26	1191.713
#477	ASCL2	2	25	27	1132.784
#478	TBX3	2	20	22	699.434
#479	ZNF202	2	12	14	176.155
#480	PROX1	2	18	20	944.381
#481	HOXA2	2	22	24	732.146
#482	ZNF134	2	25	27	1050.837
#483	TSC22D1	1	21	22	487.915
#484	HOXA3	1	24	25	291.843
#485	EGR3	1	13	14	692.313
#486	TAF1B	1	20	21	162.626
#487	ZHX2	1	17	18	54.934
#488	ZNF274	1	23	24	23.887
#489	FOXO1	1	13	14	134.595
#490	EGR2	1	11	12	16.607
#491	ZFP36L1	1	22	23	125.795
#492	ZNF117	1	26	27	118.519
#493	SOX6	1	23	24	146.302
#494	HIF3A	1	19	20	543.635
#495	FOXL2	1	19	20	124.912
#496	CTBP1	0	29	29	0
#497	TAF4B	0	20	20	0
#498	IRF5	0	21	21	0
#499	ZNF268	0	20	20	0
#500	ZIC1	0	26	26	0