Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ERG	46	4	50	764.033
#2	PBX3	43	6	49	10328.625
#3	PKNOX1	42	3	45	646.753
#4	MAFF	41	3	44	580.606
#5	JUNB	40	2	42	140.233
#6	ZNF394	39	2	41	4747.817
#7	PHTF1	39	7	46	594.393
#8	JUND	38	4	42	940.698
#9	SOX12	38	2	40	787.098
#10	HOXB3	38	5	43	720.151
#11	ZNF323	37	6	43	935.442
#12	MTA1	37	3	40	265.643
#13	TSC22D2	36	4	40	292.628
#14	HOXB2	36	4	40	158.643
#15	IRF2	35	2	37	402.286
#16	SPI1	33	3	36	3242.682
#17	BCL6	32	13	45	1682.446
#18	CEBPD	32	9	41	1018.536
#19	DDIT3	31	6	37	1014.025
#20	KDM5B	31	8	39	706.55
#21	TGIF2	31	4	35	1172.77
#22	ZNF3	31	6	37	520.034
#23	FOSL1	30	6	36	508.158
#24	ZNF193	30	10	40	2253.236
#25	HOXA4	30	8	38	326.431
#26	GABPB1	30	1	31	44.794
#27	LASS6	29	11	40	862.019
#28	ETV6	29	9	38	1180.43
#29	ZNF133	29	11	40	1382.023
#30	HOXA9	29	4	33	313.247
#31	TCF7	28	1	29	96.74
#32	ZNF434	28	3	31	239.346
#33	ETS1	28	2	30	1516.165
#34	RUNX3	28	7	35	1761.935
#35	NFKB2	28	5	33	771.765
#36	NR4A2	28	11	39	3778.088
#37	HCLS1	28	8	36	2367.931
#38	CREBBP	27	2	29	451.132
#39	HDAC1	27	9	36	3784.516
#40	FOXO4	27	13	40	1418.694
#41	NFIC	27	6	33	1148.318
#42	ZNF140	27	1	28	116.623
#43	HOXB6	27	6	33	1192.369
#44	CREBL2	27	7	34	735.392
#45	HDAC2	27	9	36	848.024
#46	TRIM28	27	8	35	1217.893
#47	SCMH1	27	9	36	993.098
#48	FOXO3	27	14	41	6211.12
#49	HMGA1	26	1	27	37.845
#50	HOXA10	26	3	29	1183.634
#51	IKZF3	25	3	28	1754.647
#52	ARNTL	25	9	34	3653.152
#53	FOXO1	25	14	39	4710.959
#54	HMGB1	24	7	31	1365.758
#55	ENO1	24	9	33	681.984
#56	IRF8	24	13	37	1948.364
#57	ZNF187	24	5	29	265.324
#58	ZKSCAN1	24	8	32	563.477
#59	NR4A1	24	11	35	2091.528
#60	ZSCAN18	23	12	35	1026.882
#61	BCL11B	23	4	27	83.903
#62	GATA2	23	8	31	620.332
#63	RUNX1	23	10	33	2020.394
#64	BCL3	23	9	32	1452.573
#65	PURA	23	15	38	4999.463
#66	CEBPA	23	14	37	5617.248
#67	ZNF189	22	9	31	993.699
#68	ZKSCAN4	22	11	33	800.507
#69	ADNP	22	5	27	942.597
#70	POU2F2	22	9	31	1302.121
#71	HOXA5	22	5	27	290.548
#72	ZNF639	22	9	31	643.828
#73	BLZF1	22	8	30	1103.362
#74	ZNF167	22	7	29	467.358
#75	CIR1	22	9	31	1104.446
#76	HNRNPAB	22	9	31	1802.968
#77	VDR	22	10	32	1391.652
#78	TBX21	22	5	27	305.473
#79	GCFC1	22	7	29	1070.203
#80	MEF2A	22	13	35	1539.777
#81	TAF12	21	10	31	3764.722
#82	ZNF175	21	15	36	2605.254
#83	ZXDC	21	11	32	1777.192
#84	REL	21	7	28	1563.647
#85	E2F3	21	14	35	4223.776
#86	MEIS1	21	15	36	3803.766
#87	KLF6	21	5	26	1241.725
#88	ZNF24	21	10	31	1472.494
#89	HMG20A	21	9	30	486.99
#90	HOXC4	21	8	29	233.68
#91	ZNF268	21	7	28	613.294
#92	ETS2	21	14	35	2162.906
#93	ZNF33B	20	14	34	681.533
#94	YEATS4	20	6	26	1433.676
#95	FOSL2	20	7	27	437.298
#96	RELA	20	11	31	628.382
#97	FUBP1	20	6	26	300.635
#98	KLF2	20	10	30	2722.372
#99	FOS	20	5	25	112.478
#100	FOXM1	20	3	23	126.124
#101	TADA2A	20	8	28	449.504
#102	E2F5	20	14	34	1293.122
#103	TFCP2	20	9	29	626.023
#104	SALL2	20	8	28	1783.697
#105	NR3C1	20	15	35	6335.178
#106	HOXA6	19	3	22	319.473
#107	HHEX	19	13	32	1099.015
#108	NFE2L1	19	7	26	1031.392
#109	TFEC	19	15	34	1996.301
#110	MEF2D	19	12	31	1322.654
#111	BTG2	19	8	27	1019.786
#112	ZHX2	19	14	33	4544.533
#113	SCML2	18	15	33	1711.102
#114	ZNF274	18	11	29	1375.742
#115	ESRRA	18	4	22	561.315
#116	BHLHE40	18	10	28	1970.682
#117	NFAT5	18	10	28	1126.993
#118	ZSCAN16	18	8	26	1456.603
#119	FOSB	18	3	21	247.256
#120	CBFA2T3	18	10	28	420.63
#121	XBP1	18	9	27	926.284
#122	NCOR1	18	4	22	112.473
#123	STAT6	18	11	29	1204.955
#124	MLX	18	14	32	1778.383
#125	MAFB	18	11	29	1770.967
#126	CEBPB	18	7	25	686.232
#127	NANOG	18	9	27	467.979
#128	RORA	18	2	20	47.113
#129	HIF1A	18	8	26	445.197
#130	GABPA	17	5	22	206.108
#131	ZEB1	17	17	34	2686.545
#132	TGIF1	17	17	34	1221.649
#133	MTF1	17	11	28	695.888
#134	KLF10	17	9	26	1449.456
#135	NR3C2	17	7	24	3046.98
#136	KLF11	17	12	29	3012.153
#137	MYCL1	17	11	28	1335.836
#138	BRD8	17	14	31	1065.941
#139	CSDA	17	10	27	1987.521
#140	E2F6	17	10	27	1147.583
#141	GATA3	17	9	26	773.556
#142	RCOR1	17	14	31	910.186
#143	HOXA2	17	9	26	392.701
#144	ERF	17	11	28	623.332
#145	FBXW7	17	13	30	2652.036
#146	ZNF131	17	13	30	1506.422
#147	ZNF75D	16	11	27	1682.132
#148	RBPJ	16	10	26	1890.303
#149	MECOM	16	10	26	3184.26
#150	BUD31	16	10	26	1346.494
#151	ARNT	16	15	31	1911.937
#152	NR4A3	16	12	28	905.185
#153	ADNP2	16	11	27	535.657
#154	ZNF85	16	12	28	779.653
#155	ELF1	16	9	25	2620.912
#156	KLF1	16	15	31	1688.191
#157	PPARD	16	10	26	1479.679
#158	TFEB	15	12	27	1631.848
#159	NFIL3	15	13	28	447.684
#160	NR1D2	15	13	28	1904.178
#161	TAF10	15	8	23	1956.744
#162	E2F1	15	8	23	786.66
#163	MXD1	15	12	27	891.654
#164	NR1H3	15	14	29	783.003
#165	NFIX	15	10	25	582.705
#166	ELK4	15	14	29	971.632
#167	KLF12	15	13	28	937.539
#168	TADA3	15	7	22	1281.755
#169	HSF2	15	14	29	2937.828
#170	PLAG1	15	14	29	5359.498
#171	KLF7	15	18	33	2070.483
#172	STAT4	15	18	33	4130.914
#173	KLF3	15	14	29	1887.601
#174	E2F8	15	8	23	857.129
#175	RXRA	15	11	26	1141.52
#176	FOXC1	14	15	29	1652.751
#177	CBFA2T2	14	11	25	1810.83
#178	ZGPAT	14	9	23	587.081
#179	TCF25	14	11	25	610.443
#180	TRIM22	14	14	28	1959.106
#181	TFDP2	14	19	33	3598.283
#182	CREBZF	14	10	24	1117.301
#183	ZEB2	14	9	23	703.615
#184	ATF3	14	10	24	308.888
#185	TSC22D1	14	15	29	1424.628
#186	MAX	14	14	28	341.826
#187	ZNF135	14	15	29	1322.963
#188	ETV3	14	11	25	6581.874
#189	REXO4	13	10	23	910.705
#190	KLF9	13	15	28	3969.457
#191	HOXB5	13	9	22	460.45
#192	TCEAL1	13	12	25	747.325
#193	JUN	13	6	19	160.073
#194	TCF4	13	19	32	1480.867
#195	STAT1	13	10	23	1414.13
#196	NFYB	13	16	29	2543.539
#197	ATF1	13	7	20	832.892
#198	ELF4	13	23	36	1800.372
#199	LHX6	13	15	28	3869.06
#200	NFE2	13	10	23	2025.925
#201	CITED2	13	21	34	2620.611
#202	PTTG1	13	12	25	794.104
#203	UBN1	13	11	24	379.783
#204	PBX1	13	14	27	3076.843
#205	RARB	13	20	33	1957.56
#206	LASS2	13	11	24	1760.891
#207	RCAN1	13	16	29	1478.524
#208	SATB1	13	11	24	1386.891
#209	HOXB9	13	12	25	1048.136
#210	ZNF444	13	9	22	747.234
#211	LZTR1	13	13	26	1275.724
#212	KLF4	12	18	30	3993.723
#213	MMP14	12	12	24	3508.238
#214	VENTX	12	23	35	2997.569
#215	HOXB7	12	12	24	577.302
#216	MSL3	12	12	24	1251.847
#217	HEY1	12	16	28	4607.194
#218	ZNF134	12	18	30	1116.536
#219	NPAT	12	14	26	1695.69
#220	SNAPC5	12	12	24	524.333
#221	ESR1	12	11	23	2103.708
#222	GTF2I	12	19	31	1563.325
#223	CTBP1	12	9	21	1790.961
#224	AEBP1	12	18	30	1900.157
#225	STAT5A	12	12	24	583.657
#226	TULP4	12	16	28	1869.989
#227	PRDM2	12	17	29	2618.81
#228	AR	11	17	28	5213.074
#229	HESX1	11	15	26	2875.008
#230	PA2G4	11	12	23	678.492
#231	ZNF202	11	16	27	974.827
#232	LEF1	11	16	27	392.644
#233	CNOT8	11	11	22	1649.62
#234	BACH1	11	10	21	394.677
#235	IRF4	11	12	23	1540.933
#236	REST	11	15	26	575.522
#237	CREB5	11	14	25	1369.242
#238	IRX5	11	11	22	680.863
#239	ZNF83	11	14	25	1020.741
#240	EGR2	11	15	26	3512.047
#241	TAF4B	11	15	26	683.373
#242	RERE	11	11	22	839.786
#243	CUX1	11	14	25	659.085
#244	MYT1	11	8	19	1314.845
#245	FOXJ3	11	12	23	633.437
#246	ZNF219	10	12	22	1231.157
#247	HMGA2	10	16	26	2083.739
#248	SCML1	10	20	30	1482.311
#249	GAS7	10	23	33	1339.423
#250	MLL	10	13	23	4195.28
#251	NFIB	10	10	20	2094.584
#252	ZFPM2	10	6	16	1134.07
#253	ARNTL2	10	16	26	713.718
#254	AHR	10	15	25	2000.629
#255	NFYA	10	15	25	1258.117
#256	SCAND2	10	11	21	649.631
#257	MSRB2	10	11	21	332.469
#258	PHF1	10	10	20	610.765
#259	OLIG2	10	9	19	566.393
#260	HOXA7	10	6	16	87.843
#261	MYBL2	10	11	21	342.189
#262	TP53	10	16	26	1686.488
#263	SIM2	10	16	26	1536.118
#264	ELF2	10	13	23	998.265
#265	GTF2H4	10	17	27	768.542
#266	TFAM	10	12	22	659.62
#267	ZKSCAN5	10	10	20	641.359
#268	SPEN	10	12	22	1203.646
#269	YY1	10	10	20	1707.319
#270	CREB3L2	10	16	26	561.138
#271	TAF4	10	13	23	1385.037
#272	RFXANK	10	9	19	999.845
#273	DMTF1	10	14	24	1865.229
#274	ZNF207	10	14	24	1145.028
#275	MNT	9	15	24	839.316
#276	SMAD3	9	13	22	1560.495
#277	BATF	9	13	22	669.742
#278	GLI2	9	14	23	5777.68
#279	ZNF45	9	17	26	3377.132
#280	RXRB	9	15	24	727.161
#281	RELB	9	8	17	1223.395
#282	AATF	9	24	33	1456.201
#283	DLX2	9	16	25	1857.537
#284	ALS2CR8	9	14	23	696.086
#285	ARID4A	9	14	23	1593.931
#286	NR2C1	9	12	21	1700.765
#287	IRF9	9	14	23	1252.456
#288	NOLC1	9	14	23	1176.489
#289	NR1I2	9	11	20	1035.124
#290	TAF5L	9	14	23	518.467
#291	MAF	9	22	31	4730.285
#292	ZBTB17	9	13	22	542.684
#293	GTF2H3	9	17	26	1470.212
#294	SATB2	9	9	18	1107.557
#295	ZNF232	9	20	29	1112.624
#296	ZNF500	9	16	25	1178.793
#297	PRDM1	9	13	22	839.358
#298	ZNF174	9	12	21	704.409
#299	NFX1	9	15	24	923.424
#300	CREB1	9	18	27	1580.115
#301	SMAD4	9	17	26	2090.257
#302	SLC2A4RG	9	14	23	1134.176
#303	EGR3	8	13	21	1293.017
#304	TSC22D3	8	12	20	2760.155
#305	PEG3	8	13	21	1842.641
#306	CNOT7	8	15	23	2240.01
#307	AHCTF1	8	15	23	1001.877
#308	IKZF1	8	19	27	1003.617
#309	HSF1	8	9	17	808.596
#310	MAFG	8	11	19	979.385
#311	TCF20	8	10	18	1811.354
#312	ZNF263	8	11	19	690.218
#313	SOX13	8	11	19	2948.693
#314	USF2	8	9	17	985.29
#315	SMAD1	8	18	26	1453.51
#316	TAF6	8	15	23	1103.998
#317	TCF7L2	8	25	33	1642.044
#318	EGR4	8	7	15	1248.663
#319	MEF2C	8	16	24	1606.143
#320	NFE2L3	8	15	23	1154.438
#321	GATA1	8	12	20	336.218
#322	FLI1	8	14	22	1440.778
#323	STAT5B	8	16	24	954.058
#324	TCF12	8	19	27	1412.231
#325	TARDBP	8	14	22	1287.486
#326	TCF3	8	21	29	845.505
#327	ZNF238	8	14	22	682.594
#328	ZNF132	8	12	20	885.971
#329	WT1	8	19	27	687.48
#330	ZNF165	7	22	29	3225.693
#331	LMO4	7	11	18	385.512
#332	NR2F2	7	11	18	1044.506
#333	HMGB2	7	13	20	785.197
#334	MYNN	7	14	21	782.513
#335	ETV1	7	10	17	750.589
#336	NFYC	7	13	20	404.403
#337	MEIS3P1	7	18	25	708.085
#338	HOPX	7	27	34	2500.285
#339	TRIM25	7	16	23	651.542
#340	PLSCR1	7	18	25	1048.405
#341	PFDN1	7	15	22	1083.338
#342	BACH2	7	15	22	733.09
#343	ZNF117	7	20	27	1387.12
#344	RFX5	7	12	19	1205.31
#345	SP1	7	14	21	696.741
#346	SP140	7	11	18	432.774
#347	RB1	7	15	22	526.996
#348	TFCP2L1	7	7	14	620.58
#349	TEAD4	7	14	21	1599.789
#350	ZBTB48	7	13	20	503.145
#351	TFAP2B	7	9	16	1090.344
#352	ATF2	7	11	18	466.049
#353	ZNF148	7	13	20	1294.214
#354	NOTCH1	7	18	25	3220.387
#355	PLAGL2	7	13	20	628.225
#356	EGR1	7	14	21	886.929
#357	NR6A1	7	13	20	664.04
#358	MGA	7	12	19	304.235
#359	HMBOX1	7	15	22	2020.842
#360	ZNF154	6	16	22	1789.429
#361	ZNF217	6	12	18	1776.197
#362	HOXA11	6	10	16	471.94
#363	GRHL2	6	14	20	1248.312
#364	ZBTB38	6	21	27	3899.13
#365	IRF7	6	17	23	2190.738
#366	ZNF91	6	15	21	450.478
#367	POU6F1	6	13	19	515.894
#368	DRAP1	6	12	18	367.202
#369	IRF5	6	25	31	1107.532
#370	GATAD1	6	17	23	658.284
#371	NKX2-5	6	5	11	272.578
#372	HOXA1	6	10	16	614.682
#373	VAV1	6	22	28	2868.265
#374	ATF5	6	26	32	873.826
#375	TFDP1	6	13	19	929.322
#376	TFE3	6	10	16	439.587
#377	HIF3A	6	9	15	917.702
#378	SUPT4H1	6	10	16	1427.228
#379	FOXN3	6	8	14	699.686
#380	ARID3A	6	11	17	332.137
#381	HINFP	6	11	17	472.038
#382	ESR2	6	14	20	291.545
#383	NR2C2	6	12	18	326.28
#384	BTAF1	6	11	17	1447.043
#385	PAX8	6	15	21	1148.59
#386	ELK1	6	15	21	238.207
#387	STAT2	6	13	19	1170.17
#388	MEIS2	6	10	16	332.382
#389	C2orf3	6	13	19	549.106
#390	TAF7	5	22	27	1325.336
#391	GTF2IRD1	5	16	21	1538.181
#392	NFKB1	5	13	18	718.716
#393	IRF6	5	14	19	862.19
#394	ALX1	5	6	11	264.41
#395	TFAP4	5	13	18	923.595
#396	KLF5	5	22	27	3668.054
#397	E2F4	5	9	14	199.015
#398	ZNF277	5	16	21	725.429
#399	CREM	5	19	24	976.557
#400	KDM5A	5	20	25	2303.801
#401	ELF5	5	13	18	1352.316
#402	CSRNP2	5	10	15	407.084
#403	ZSCAN2	5	17	22	1826.352
#404	POU4F1	5	6	11	645.365
#405	PPARG	5	13	18	492.569
#406	ZFP36L1	5	15	20	1335.147
#407	CBFB	5	20	25	832.176
#408	MITF	5	23	28	1255.48
#409	C11orf9	5	14	19	635.964
#410	FOXF1	5	10	15	956.215
#411	ZSCAN5A	5	13	18	829.527
#412	TWIST1	5	23	28	841.709
#413	NR2E3	5	17	22	313.852
#414	SOX4	5	20	25	2090.774
#415	BHLHE41	4	17	21	1695.163
#416	FOXJ2	4	16	20	795.352
#417	SPIB	4	6	10	1306.597
#418	TBX19	4	16	20	428.69
#419	RBCK1	4	15	19	390.868
#420	CUX2	4	22	26	1172.995
#421	TBX1	4	14	18	1136.106
#422	MYC	4	21	25	814.191
#423	HOXB8	4	5	9	37.279
#424	ZFHX3	4	11	15	489.342
#425	ZSCAN12	4	21	25	469.842
#426	HLF	4	21	25	709.705
#427	MYCN	4	21	25	2586.757
#428	NFATC1	4	21	25	708.393
#429	IRF1	4	14	18	1515.387
#430	AFF1	4	18	22	661.51
#431	PITX1	4	6	10	685.953
#432	ELK3	4	17	21	574.453
#433	ZNF215	4	12	16	2390.908
#434	TAL1	4	22	26	1405.592
#435	RFX3	4	11	15	264.39
#436	RUNX2	4	16	20	2358.302
#437	NR2F6	4	17	21	1199.944
#438	ZNF35	4	12	16	315.248
#439	FOXN2	4	13	17	409.645
#440	ZHX3	3	18	21	1248.949
#441	ZNF155	3	14	17	683.589
#442	E2F2	3	13	16	3817.665
#443	SMAD2	3	16	19	1962.269
#444	SMAD5	3	25	28	267.83
#445	FOXK2	3	17	20	145.855
#446	MLLT10	3	17	20	1930.3
#447	SREBF2	3	23	26	1900.419
#448	TAF5	3	15	18	193.344
#449	ST18	3	16	19	1144.522
#450	POU2F1	3	14	17	561.133
#451	DLX4	3	20	23	303.587
#452	TAF13	3	12	15	228.408
#453	HMG20B	3	20	23	547.298
#454	SNAPC4	3	14	17	874.201
#455	RARA	3	15	18	418.814
#456	TCFL5	3	19	22	571.027
#457	HES1	2	20	22	726.589
#458	TCF7L1	2	15	17	435.575
#459	NFE2L2	2	15	17	216.807
#460	ZNF643	2	19	21	371.194
#461	PBX2	2	17	19	524.676
#462	CREB3L1	2	16	18	1128.632
#463	CREB3	2	19	21	288.01
#464	SMAD6	2	26	28	729.289
#465	ZNF281	2	19	21	305.246
#466	STAT3	2	23	25	249.015
#467	NR5A2	2	13	15	623.909
#468	BATF3	2	14	16	699.093
#469	PCGF2	2	12	14	99.512
#470	RNF4	2	14	16	1072.901
#471	TRPS1	2	23	25	1113.657
#472	ZNF93	2	19	21	217.126
#473	IRF3	2	16	18	748.342
#474	ATF6	2	19	21	209.689
#475	CLOCK	2	16	18	233.943
#476	CEBPE	2	18	20	448.113
#477	EPAS1	2	23	25	1792.233
#478	ECSIT	2	17	19	92.092
#479	ZFP36L2	2	17	19	585.381
#480	TAF1B	1	11	12	222.34
#481	SP4	1	17	18	87.447
#482	NFATC3	1	16	17	234.573
#483	TP63	1	19	20	1257.06
#484	CCRN4L	1	12	13	219.444
#485	DBP	1	13	14	233.455
#486	ZBTB25	1	18	19	56.98
#487	SUPT6H	1	14	15	646.866
#488	ATF6B	1	17	18	1262.565
#489	NKX3-1	1	15	16	39.973
#490	THRA	1	12	13	104.425
#491	ZNF236	1	18	19	49.391
#492	SREBF1	1	16	17	588.258
#493	MZF1	1	17	18	72.66
#494	SOLH	0	15	15	0
#495	SOX15	0	18	18	0
#496	CDKN2A	0	21	21	0
#497	ETV5	0	25	25	0
#498	CBL	0	17	17	0
#499	STRN3	0	21	21	0
#500	HNF4A	0	8	8	0