Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HIRA	81	4	85	1365.705
#2	FOXP3	78	2	80	91.567
#3	FOXO1	71	6	77	193.912
#4	TFDP2	69	3	72	440.992
#5	ADNP2	68	4	72	2392.209
#6	MEF2C	64	4	68	356.643
#7	BCL11B	62	1	63	43.993
#8	NFATC1	58	8	66	1710.228
#9	ELF3	58	3	61	65.228
#10	ZNF394	56	3	59	79.824
#11	MTF1	55	7	62	1439.955
#12	ECSIT	55	11	66	813.694
#13	HOXA6	54	7	61	4817.339
#14	TAF12	53	12	65	2208.243
#15	C11orf9	52	8	60	4911.573
#16	GABPA	51	21	72	5828.443
#17	NFYB	49	17	66	6381.336
#18	TLX1	49	9	58	1150.655
#19	BACH2	49	11	60	1618.605
#20	HOXC10	49	10	59	2058.419
#21	BTG2	48	3	51	194.398
#22	TCF3	48	1	49	21.745
#23	MGA	47	10	57	1234.795
#24	SUPT6H	47	18	65	4002.997
#25	ZFP36L2	47	4	51	275.918
#26	ZHX2	46	9	55	6627.205
#27	ZNF140	45	14	59	632.689
#28	ZEB2	43	9	52	366.752
#29	ZNF3	43	13	56	1350.745
#30	NOTCH1	43	10	53	3282.299
#31	TRIM25	42	9	51	813.616
#32	TCFL5	42	9	51	1029.689
#33	ZNF75D	42	18	60	5752.823
#34	ELK3	41	7	48	124.537
#35	TCF4	41	6	47	161.369
#36	KLF1	41	4	45	833.664
#37	ZGPAT	40	13	53	4063.078
#38	ZNF45	40	14	54	4806.721
#39	JUNB	39	5	44	1489.518
#40	ZXDC	39	15	54	1337.453
#41	SPEN	39	11	50	800.724
#42	HNF1A	39	8	47	791.925
#43	SOX4	39	13	52	4274.506
#44	TFEB	38	5	43	1237.213
#45	HHEX	38	7	45	438.149
#46	KLF6	38	0	38	0
#47	SMAD1	37	8	45	269.786
#48	FOXF1	37	11	48	2649.653
#49	MAFF	36	5	41	87.003
#50	TP53	36	10	46	3247.989
#51	MAX	36	14	50	2069.448
#52	ATF3	36	4	40	141.414
#53	MZF1	36	14	50	2814.1
#54	MITF	35	16	51	4340.827
#55	JUND	35	7	42	670.635
#56	PPARA	34	10	44	2281.258
#57	ENO1	34	8	42	3436.37
#58	STAT3	34	12	46	3931.309
#59	ARNT	33	18	51	1044.831
#60	IKZF1	33	4	37	702.933
#61	RB1	33	10	43	811.715
#62	POU5F1B	33	7	40	445.154
#63	TSC22D3	33	5	38	213.196
#64	GTF2I	33	6	39	228.517
#65	HMG20B	32	6	38	453.696
#66	NR3C1	32	7	39	357.575
#67	CEBPB	32	12	44	562.842
#68	IRF8	32	11	43	1316.138
#69	RELA	32	0	32	0
#70	CITED2	31	16	47	7060.926
#71	NFE2	31	9	40	886.425
#72	XBP1	31	9	40	723.649
#73	YY1	31	13	44	634.324
#74	CEBPE	31	18	49	6647.775
#75	ZSCAN16	30	15	45	2378.449
#76	BHLHE40	30	9	39	492.919
#77	PKNOX2	30	19	49	3325.358
#78	NKX3-1	30	10	40	548.291
#79	RXRA	30	15	45	3632.884
#80	ERG	30	8	38	166.668
#81	KLF10	30	7	37	374.453
#82	NFYA	30	8	38	363.939
#83	FOSL2	30	9	39	1819.014
#84	CTBP1	30	15	45	7804.719
#85	ZBTB48	29	16	45	2873.95
#86	HMGA1	29	11	40	806.956
#87	HR	29	14	43	2330.877
#88	HSF1	29	20	49	1233.617
#89	MBD1	29	14	43	1890.209
#90	TAL1	29	3	32	1540.145
#91	IRF2	28	12	40	1328.309
#92	ZKSCAN1	28	8	36	164.787
#93	LEF1	28	8	36	344.009
#94	TFE3	28	16	44	1936.247
#95	TCF7	28	5	33	998.961
#96	CSDA	28	12	40	1442.63
#97	ZNF444	27	21	48	1505.397
#98	NR2F1	27	9	36	833.887
#99	TEAD1	27	18	45	5328.07
#100	ZNF167	27	13	40	423.498
#101	KDM5B	27	16	43	2467.189
#102	ETS2	26	12	38	394.827
#103	NR4A3	26	8	34	147.669
#104	FOS	26	7	33	626.777
#105	SOX5	25	22	47	3020.813
#106	FOXA1	25	22	47	4205.447
#107	NR4A1	25	8	33	501.099
#108	ELF4	25	20	45	862.815
#109	BCL3	25	13	38	2058.613
#110	ZNF187	25	15	40	1584.388
#111	REXO4	25	12	37	1465.354
#112	FLI1	25	12	37	470.669
#113	MYC	25	21	46	6174.094
#114	STAT6	25	8	33	714.897
#115	BATF	25	21	46	1220.538
#116	HES1	25	9	34	288.88
#117	KLF2	25	10	35	311.718
#118	ZNF193	25	15	40	319.424
#119	PURA	24	23	47	1962.956
#120	NKX2-8	24	10	34	601.246
#121	HIF3A	24	16	40	1055.137
#122	ZEB1	24	11	35	507.091
#123	RXRB	23	10	33	292.992
#124	SPI1	23	14	37	321.726
#125	MYF6	23	16	39	964.415
#126	SCML1	23	18	41	1785.344
#127	PLSCR1	23	22	45	1720.315
#128	ZNF277	23	12	35	803.509
#129	HOXB1	22	20	42	1515.4
#130	MLL	22	15	37	1125.306
#131	VAX2	22	14	36	1770.26
#132	MYCN	22	14	36	1913.344
#133	ZNF174	22	20	42	3157.947
#134	SPDEF	22	15	37	502.845
#135	GATA3	22	9	31	89.748
#136	MYT1	22	10	32	180.917
#137	NFATC4	22	9	31	523.417
#138	ASCL2	21	27	48	2328.176
#139	SPIB	21	9	30	390.854
#140	TBR1	21	16	37	1855.87
#141	HOXD4	21	20	41	2318.556
#142	KLF11	21	16	37	3413.237
#143	ZNF238	21	16	37	785.733
#144	GABPB1	21	20	41	835.064
#145	GATA2	20	19	39	1416.114
#146	NR4A2	20	7	27	2106.515
#147	BCL6	20	16	36	473.774
#148	RORC	20	22	42	3428.977
#149	NPAT	20	12	32	1977.882
#150	EGR3	20	9	29	205.88
#151	HOXA10	20	8	28	666.01
#152	PBX1	20	12	32	995.495
#153	ZNF132	19	27	46	3730.382
#154	NEUROG1	19	17	36	750.516
#155	MEF2A	19	15	34	1092.011
#156	PHF1	19	12	31	972.49
#157	AEBP1	19	15	34	887.211
#158	SOX11	19	8	27	924.031
#159	SOX9	19	23	42	1028.434
#160	RARG	19	24	43	1916.057
#161	CREB3	19	21	40	2240.934
#162	PDX1	19	18	37	3450.615
#163	EMX1	19	21	40	2325.095
#164	FBXW7	19	11	30	695.956
#165	CEBPD	19	12	31	687.909
#166	KLF9	19	16	35	350.984
#167	TFDP1	19	12	31	888.285
#168	HOXD9	18	16	34	612.648
#169	GLI2	18	23	41	819.556
#170	HINFP	18	19	37	605.99
#171	SREBF1	18	16	34	795.078
#172	ALX4	18	22	40	1431.072
#173	TBX6	18	24	42	1743.586
#174	CBL	18	15	33	235.558
#175	HOXC8	18	14	32	703.529
#176	PAX4	18	22	40	4985.827
#177	OLIG2	17	24	41	2013.512
#178	RUNX2	17	26	43	1229.666
#179	BLZF1	17	17	34	409.967
#180	RUNX3	17	12	29	510.468
#181	PITX2	17	27	44	2217.208
#182	MEIS1	17	11	28	369.939
#183	PAX6	17	19	36	1163.38
#184	ZNF35	17	23	40	1320.566
#185	HOXB2	17	23	40	939.398
#186	TADA3	17	16	33	819.323
#187	E2F6	17	18	35	414.356
#188	CRX	17	11	28	955.118
#189	ELK4	17	18	35	969.907
#190	NFIC	17	14	31	581.558
#191	GAS7	17	16	33	592.409
#192	NFIX	17	15	32	350.929
#193	MYBL2	17	16	33	1560.702
#194	E2F8	17	19	36	1908.199
#195	ELF5	17	23	40	1089.079
#196	FOXM1	17	14	31	1210.575
#197	NFIL3	17	15	32	364.345
#198	ZIC1	17	18	35	5321.856
#199	HOXB9	16	11	27	924.969
#200	ZBTB17	16	16	32	474.541
#201	PPARD	16	14	30	1802.775
#202	FOXO3	16	9	25	168.648
#203	FOXC2	16	11	27	1231.89
#204	MSRB2	16	18	34	641.652
#205	TWIST1	16	19	35	1001.004
#206	MXD1	16	15	31	435.23
#207	NEUROD1	15	20	35	776.633
#208	ZNF80	15	14	29	2140.764
#209	PHOX2A	15	19	34	1124.986
#210	E2F1	15	13	28	334.557
#211	SP140	15	22	37	392.073
#212	SMAD5	15	21	36	1752.162
#213	PAX7	15	20	35	4815
#214	NR2E3	15	13	28	3228.644
#215	RCAN1	15	10	25	227.236
#216	IRF7	15	10	25	841.557
#217	HOXA9	15	4	19	57.547
#218	SMAD3	15	12	27	192.732
#219	TFEC	15	21	36	1261.527
#220	KLF12	15	25	40	1532.413
#221	HOXA4	15	13	28	621.332
#222	VSX1	14	20	34	942.428
#223	ST18	14	13	27	174.948
#224	NR3C2	14	8	22	219.443
#225	E2F5	14	18	32	1919.253
#226	NR0B1	14	15	29	438.764
#227	FOXE1	14	26	40	1275.161
#228	MSC	14	22	36	1482.768
#229	RFXAP	14	16	30	188.238
#230	CUX2	14	31	45	2352.551
#231	ETV5	14	31	45	2132.391
#232	HOXA5	14	4	18	338.521
#233	SCAND2	14	26	40	1544.77
#234	HOXA11	14	18	32	789.364
#235	PAX5	14	15	29	262.356
#236	TSHZ2	14	12	26	826.517
#237	PEG3	14	18	32	1153.808
#238	DLX6	14	29	43	3117.681
#239	CDKN2A	14	19	33	1256.429
#240	ATOH1	14	20	34	1133.613
#241	TCF15	14	20	34	1281.936
#242	FOXJ1	14	15	29	932.01
#243	GATA1	14	14	28	6132.4
#244	HOXA1	14	18	32	1269.133
#245	MEIS2	13	23	36	2034.022
#246	POU3F4	13	19	32	707.449
#247	TLX2	13	24	37	2900.776
#248	RELB	13	18	31	343.339
#249	NFX1	13	21	34	1281.126
#250	SRY	13	13	26	814.66
#251	POU1F1	13	28	41	1522.244
#252	HOPX	13	21	34	726.268
#253	PPBPL2	13	20	33	854.285
#254	TSC22D2	13	14	27	2267.605
#255	ZNF323	13	17	30	254.113
#256	ALX3	13	9	22	1090.843
#257	ARID3A	13	26	39	1052.666
#258	VTN	12	22	34	1481.817
#259	MAF	12	17	29	1430.246
#260	SLC26A3	12	25	37	807.367
#261	TEAD3	12	24	36	3429.337
#262	HOXD13	12	16	28	526.923
#263	VDR	12	16	28	646.484
#264	NANOG	12	20	32	1147.016
#265	HOXB6	12	20	32	1433.863
#266	CSRNP3	12	29	41	980.687
#267	BRD8	12	21	33	1010.794
#268	ASCL1	12	19	31	1489.159
#269	ARNTL	12	25	37	641.258
#270	NRL	12	26	38	1030.508
#271	HOXB8	12	22	34	719.538
#272	ZFP36L1	12	17	29	736.763
#273	HOXD11	12	24	36	1215.764
#274	MYF5	12	23	35	1089.877
#275	TFAP2C	12	13	25	490.187
#276	FOXD3	12	21	33	1072.05
#277	DBP	11	21	32	765.948
#278	NKX2-5	11	18	29	741.426
#279	TBX5	11	34	45	1621.67
#280	POU6F2	11	21	32	903.732
#281	FOXG1	11	23	34	1187.425
#282	FOSB	11	6	17	2635.245
#283	SMAD6	11	12	23	164.598
#284	MYCL1	11	25	36	755.197
#285	STAT2	11	11	22	103.922
#286	NR2C1	11	21	32	574.008
#287	SP1	11	19	30	325.468
#288	KLF5	11	22	33	618.158
#289	RUNX1T1	11	23	34	1258.284
#290	ZNF165	11	19	30	228.669
#291	POU4F1	11	13	24	257.737
#292	SRF	11	20	31	985.488
#293	HMX1	11	22	33	806.132
#294	ZNF446	11	21	32	552.295
#295	HEY2	11	13	24	879.41
#296	RUNX1	11	19	30	244.456
#297	TFDP3	11	18	29	507.888
#298	TBX10	11	20	31	1004.831
#299	STAT1	11	14	25	1480.754
#300	PCGF2	11	14	25	680.187
#301	ATF5	11	25	36	840.975
#302	FUBP1	11	25	36	678.464
#303	HLF	11	27	38	2857.029
#304	TFAP2B	11	30	41	1355.753
#305	MSX1	10	22	32	517.688
#306	ZNF81	10	21	31	849.119
#307	ARNTL2	10	12	22	308.395
#308	NR2F2	10	19	29	693.354
#309	HNF1B	10	26	36	1159.918
#310	POU3F3	10	27	37	927.831
#311	ISL1	10	15	25	383.742
#312	DMRT1	10	27	37	628.29
#313	TEAD4	10	16	26	476.149
#314	HOXB3	10	18	28	439.564
#315	TAF4	10	21	31	346.182
#316	ETS1	10	9	19	62.648
#317	ETV4	10	15	25	2894.999
#318	SIM1	10	23	33	1937.332
#319	SIM2	10	22	32	1040.58
#320	DLX2	10	26	36	735.567
#321	EN1	10	21	31	1064.29
#322	ZNF202	10	17	27	272.867
#323	RARA	10	15	25	157.042
#324	JUN	10	10	20	336.693
#325	BNC1	10	29	39	1327.546
#326	SOX17	10	19	29	1162.224
#327	HAND2	10	26	36	4313.283
#328	IKZF3	10	13	23	283.253
#329	ZFHX3	10	20	30	310.829
#330	EGR1	10	12	22	162.43
#331	HOXA7	10	13	23	450.154
#332	AHR	10	22	32	391.07
#333	MEF2D	10	18	28	307.545
#334	E2F2	10	9	19	130.389
#335	SCRT1	9	25	34	950.964
#336	RAX	9	28	37	1342.204
#337	MYT1L	9	22	31	903.089
#338	IRX4	9	28	37	1303.464
#339	TCF21	9	18	27	419.238
#340	ZNF135	9	21	30	569.45
#341	SOX13	9	20	29	1056.584
#342	LHX2	9	23	32	691.551
#343	OVOL1	9	21	30	533.327
#344	RORA	9	22	31	432.048
#345	NKX2-1	9	8	17	710.238
#346	TFAP2A	9	23	32	786.346
#347	RORB	9	10	19	150.318
#348	MEOX2	9	21	30	850.25
#349	SIX1	9	21	30	1061.568
#350	ZSCAN2	9	17	26	260.763
#351	THRA	9	23	32	1290.629
#352	SOX2	9	23	32	1498.242
#353	TCF7L2	9	17	26	323.503
#354	ESRRG	9	17	26	1379.747
#355	MMP14	9	23	32	417.619
#356	MAFK	9	20	29	615.483
#357	GATA6	9	23	32	904.232
#358	WT1	9	15	24	855.347
#359	ZNF157	9	27	36	1575.306
#360	KLF15	9	21	30	4644.163
#361	NR1I3	9	29	38	1026.831
#362	NR5A2	8	25	33	709.666
#363	PHOX2B	8	26	34	1146.104
#364	PTH	8	30	38	1305.223
#365	SOX21	8	26	34	2028.959
#366	FOSL1	8	24	32	909.649
#367	CREB5	8	22	30	786.199
#368	TEF	8	23	31	360.63
#369	EN2	8	23	31	1225.321
#370	NR1I2	8	19	27	426.658
#371	ZNF268	8	25	33	1555.71
#372	TADA2A	8	28	36	746.347
#373	CREM	8	14	22	384.064
#374	NR1D2	8	15	23	116.738
#375	GATA4	8	21	29	1426.175
#376	TAF13	8	26	34	690.635
#377	CEBPA	8	25	33	426.489
#378	EHF	8	20	28	1833.119
#379	POU3F1	8	18	26	455.973
#380	HOXD3	8	26	34	878.38
#381	PITX1	8	22	30	789.312
#382	RERE	8	16	24	259.879
#383	ZHX3	8	17	25	1659.149
#384	HOXC13	8	22	30	477.543
#385	RBPJL	8	23	31	1172.713
#386	AR	8	23	31	1292.884
#387	PPARG	8	24	32	540.864
#388	ONECUT2	8	23	31	2465.945
#389	HNF4G	8	24	32	655.215
#390	TRPS1	8	17	25	354.252
#391	WNT5A	8	20	28	461.597
#392	MLXIPL	8	19	27	1212.685
#393	ATF6	8	20	28	173.947
#394	FOXD1	8	34	42	1514.032
#395	ZIC3	8	24	32	1306.536
#396	GSC2	7	23	30	1017.468
#397	ETV1	7	19	26	598.994
#398	HOXA2	7	20	27	786.298
#399	LHX6	7	28	35	606.101
#400	ONECUT1	7	23	30	465.272
#401	GBX2	7	19	26	607.409
#402	MNX1	7	24	31	1064.252
#403	MEOX1	7	26	33	971.716
#404	ARNT2	7	18	25	1028.387
#405	ZNF154	7	20	27	307.617
#406	HOXA3	7	14	21	195.207
#407	ERF	7	18	25	346.056
#408	ETV2	7	26	33	913.209
#409	NKX3-2	7	15	22	304.697
#410	NR5A1	7	25	32	771.527
#411	SIX3	7	24	31	954.148
#412	ZSCAN18	7	18	25	331.885
#413	RARB	7	24	31	730.361
#414	NFAT5	7	15	22	346.019
#415	NR2F6	7	17	24	275.109
#416	T	7	27	34	649.095
#417	ZNF287	7	17	24	291.109
#418	IRX5	7	11	18	417.655
#419	LHX1	7	23	30	709.319
#420	ESRRB	7	31	38	912.045
#421	TLX3	7	23	30	1777.116
#422	KLF4	7	14	21	261.34
#423	ZNF175	7	16	23	328.679
#424	PAX3	7	28	35	601.448
#425	PLAG1	7	14	21	279.278
#426	EGR4	7	27	34	838.258
#427	PRDM2	7	21	28	244.595
#428	C2orf3	7	18	25	409.667
#429	FOXH1	7	22	29	1424.354
#430	TFAP4	7	22	29	288.928
#431	TBX1	6	22	28	1245.65
#432	NPAS1	6	27	33	940.832
#433	MTA2	6	23	29	299.249
#434	SOX18	6	23	29	425.425
#435	FOXI1	6	20	26	1156.488
#436	ELK1	6	18	24	639.339
#437	FOXB1	6	21	27	1478.186
#438	FOXO4	6	17	23	550.244
#439	ZNF155	6	19	25	313.482
#440	PRDM1	6	15	21	159.554
#441	NR1H4	6	23	29	942.944
#442	BARX1	6	21	27	1291.579
#443	ZNF236	6	28	34	897.033
#444	POU2F2	6	11	17	392.265
#445	SALL1	6	20	26	326.244
#446	ZFP37	6	20	26	562.189
#447	ATF6B	6	16	22	316.627
#448	SATB2	6	27	33	403.136
#449	PGR	6	12	18	518.911
#450	ZSCAN12	6	20	26	428.064
#451	REST	5	19	24	446.773
#452	SNAPC5	5	23	28	352.226
#453	MSX2	5	26	31	315.923
#454	PKNOX1	5	30	35	488.367
#455	IRF4	5	26	31	1224.595
#456	POU4F3	5	24	29	520.549
#457	HNF4A	5	15	20	489.69
#458	ZFPM2	5	20	25	291.48
#459	ZNF41	5	25	30	191.516
#460	BHLHE41	5	25	30	1432.534
#461	ESR1	5	29	34	466.247
#462	BATF3	5	21	26	358.296
#463	NFKB2	5	19	24	350.275
#464	GTF2H4	5	23	28	256.079
#465	HOXB7	5	25	30	804.126
#466	CBFA2T2	5	22	27	226.556
#467	FOXA2	5	28	33	340.792
#468	LZTS1	5	17	22	82.663
#469	MAFB	5	11	16	251.478
#470	EGR2	5	16	21	2078.25
#471	FOXL2	5	25	30	270.704
#472	CREBBP	4	17	21	160.436
#473	ESR2	4	30	34	642.027
#474	TBX2	4	23	27	417.598
#475	POU2F3	4	25	29	704.884
#476	LMO4	4	20	24	166.025
#477	SNAI2	4	24	28	269.734
#478	PAX8	4	23	27	797.343
#479	TP63	4	25	29	268.51
#480	TAF1B	4	19	23	266.922
#481	EPAS1	4	26	30	1470.127
#482	NR6A1	4	21	25	663.978
#483	GCM1	4	24	28	598.746
#484	CREBZF	4	18	22	214.075
#485	POU3F2	4	26	30	551.943
#486	MLLT10	4	26	30	133.846
#487	FOXD2	4	24	28	561.096
#488	TBX19	3	26	29	122.139
#489	HOXD1	3	23	26	238.015
#490	HESX1	3	21	24	104.948
#491	STRN3	3	30	33	764.95
#492	NFIB	2	32	34	232.412
#493	ZNF639	2	24	26	852.012
#494	POU6F1	2	21	23	37.331
#495	ZNF643	1	28	29	61.623
#496	SLC2A4RG	1	27	28	34.656
#497	SOX30	1	30	31	171.957
#498	IRF5	1	18	19	33.715
#499	MECOM	1	29	30	189.243
#500	NPAS2	1	24	25	72.623