Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ELF3	74	4	78	2620.607
#2	LHX2	66	2	68	540.88
#3	ZHX2	58	4	62	188.359
#4	BNC1	52	8	60	3181.913
#5	PPARD	50	6	56	563.735
#6	SOX15	49	3	52	215.763
#7	PLAGL2	47	9	56	4387.554
#8	HOXA1	46	4	50	2037.644
#9	TBX2	46	5	51	227.308
#10	NR2F1	43	9	52	1665.671
#11	ZNF131	42	4	46	2709.907
#12	ZNF238	39	6	45	524.187
#13	BATF2	38	6	44	656.088
#14	LEF1	37	6	43	14565.697
#15	HOXA7	36	10	46	733.058
#16	HOXB2	35	7	42	356.028
#17	RARA	35	6	41	466.785
#18	ZNF217	34	8	42	1019.832
#19	ZSCAN18	34	9	43	1658.548
#20	TBX3	34	9	43	1575.445
#21	ZSCAN5A	34	6	40	1283.107
#22	FOXP1	33	7	40	489.95
#23	SMAD1	33	4	37	1645.331
#24	HOXA3	32	6	38	229.52
#25	PPARG	30	6	36	768.573
#26	SPDEF	30	12	42	2103.369
#27	MSX1	29	11	40	607.148
#28	GRHL2	29	7	36	3333.584
#29	TWIST2	29	4	33	74.905
#30	FOXM1	28	9	37	18173.213
#31	SALL1	28	5	33	2560.307
#32	PLSCR1	28	7	35	584.405
#33	FOXG1	27	4	31	1344.525
#34	ELK3	26	10	36	3712.06
#35	GAS7	26	9	35	1010.161
#36	ZNF175	26	11	37	1000.052
#37	STAT1	25	7	32	1632.001
#38	TCFL5	25	10	35	2047.012
#39	PBX2	25	8	33	1922.76
#40	HOXA10	25	3	28	152.959
#41	CREB3L4	25	8	33	1830.265
#42	EHF	24	12	36	673.955
#43	TFAP2C	24	8	32	1292.475
#44	CITED1	24	9	33	1039.883
#45	MEIS1	24	8	32	889.837
#46	CDKN2A	24	8	32	2500.448
#47	PHF1	24	5	29	732.242
#48	SCAND1	23	9	32	8321.543
#49	NFIX	23	9	32	750.276
#50	ZNF71	23	6	29	692.969
#51	ZHX1	22	8	30	672.669
#52	ETV5	22	9	31	7489.206
#53	PBX1	22	7	29	5455.244
#54	ZNF323	22	9	31	795.434
#55	HOPX	21	4	25	204.514
#56	SREBF1	21	9	30	3821.356
#57	TEAD2	21	4	25	1060.128
#58	FOXN2	21	7	28	2284.983
#59	RCAN1	21	9	30	1306.976
#60	HMGB1	20	10	30	677.688
#61	RFXANK	20	6	26	4726.398
#62	PURA	20	7	27	4775.504
#63	SMAD4	20	6	26	582.734
#64	BATF	19	8	27	175.11
#65	ESRRA	19	8	27	3982.989
#66	ZNF232	19	10	29	6512.612
#67	HOXA2	19	7	26	310.209
#68	TWIST1	19	7	26	497.978
#69	SALL2	19	7	26	1538.569
#70	VDR	18	11	29	630.626
#71	RUNX2	18	9	27	1051.691
#72	TCF7	18	7	25	117.917
#73	NR2F2	18	8	26	433.204
#74	NFIA	18	8	26	3092.831
#75	MSX2	18	9	27	1067.831
#76	HOXB6	18	5	23	188.424
#77	ZEB1	18	3	21	117.732
#78	DLX1	18	10	28	3151.355
#79	ISL2	17	6	23	1250.251
#80	ATF5	17	5	22	379.298
#81	ETS2	17	8	25	1031.361
#82	SIX1	17	7	24	232.532
#83	ZKSCAN1	17	10	27	3056.856
#84	MYPOP	17	10	27	2430.718
#85	TFCP2L1	16	8	24	13697.187
#86	SNAPC5	16	5	21	72.876
#87	ZFPM1	16	11	27	2074.557
#88	ZNF81	16	9	25	4753.773
#89	MYNN	16	10	26	5698.825
#90	FOXC1	16	3	19	153.36
#91	ZNF33B	16	9	25	7660.651
#92	HOXC4	15	8	23	3521.089
#93	HOXC10	15	8	23	832.03
#94	CREB1	15	7	22	14774.463
#95	NFIB	15	11	26	878.099
#96	KDM5B	15	11	26	966.972
#97	CTBP1	15	7	22	2319.687
#98	TFAM	14	10	24	1571.969
#99	TRPS1	14	9	23	10489.028
#100	NR1D2	14	13	27	1908.28
#101	NPAS2	14	10	24	655.22
#102	BARX1	14	6	20	70.971
#103	FOXO1	14	9	23	3428.918
#104	LASS6	14	8	22	234.128
#105	RB1	14	9	23	734.693
#106	STAT6	14	13	27	8360.732
#107	MEF2A	14	8	22	9578.554
#108	TFE3	14	7	21	2388.344
#109	ZNF24	14	9	23	6627.317
#110	ZFHX3	13	7	20	500.408
#111	TCF4	13	11	24	1089.554
#112	IRF5	13	10	23	1616.083
#113	SNAI2	13	10	23	2135.85
#114	GLI3	13	7	20	353.455
#115	NPAT	13	7	20	502.783
#116	ETS1	13	8	21	1338.496
#117	MLLT10	13	11	24	289.384
#118	SOX13	13	12	25	1270.234
#119	HIF3A	13	12	25	727.418
#120	MGA	13	8	21	545.655
#121	TCF12	13	10	23	1025.146
#122	TEAD1	13	8	21	918.103
#123	HOXA13	13	7	20	185.303
#124	HHEX	13	10	23	305.621
#125	OVOL1	13	11	24	3778.578
#126	GATA6	12	8	20	559.946
#127	FOXQ1	12	7	19	14097.793
#128	GTF2H4	12	6	18	985.898
#129	JDP2	12	9	21	953.602
#130	HOXB5	12	8	20	228.415
#131	LASS5	12	10	22	14988.186
#132	ZNF33A	12	7	19	12973.142
#133	TRIM28	12	7	19	4166.92
#134	NR2C2	12	8	20	608.027
#135	ARNTL2	12	8	20	2329.306
#136	HOXD9	12	8	20	587.769
#137	TRERF1	12	7	19	962.562
#138	PCGF2	12	9	21	3861.632
#139	UBP1	12	10	22	771.443
#140	MESP1	11	8	19	2652.335
#141	SUPT4H1	11	10	21	270.528
#142	PHF5A	11	7	18	701.398
#143	TFEB	11	7	18	335.665
#144	NFE2L1	11	9	20	705.138
#145	HEY1	11	10	21	99.56
#146	HOXC13	11	8	19	4804.241
#147	HOXB13	11	5	16	485.73
#148	HSF1	11	12	23	1344.397
#149	FOXL1	11	10	21	136.273
#150	CLOCK	11	5	16	161.476
#151	C1orf85	11	10	21	1022.496
#152	NFE2L3	11	9	20	4877.466
#153	TAF1B	11	12	23	2192.547
#154	GATA3	11	12	23	653.246
#155	PTTG1	11	7	18	513.607
#156	GTF2H2	11	9	20	2029.959
#157	SMAD9	11	8	19	2063.474
#158	AHCTF1	11	7	18	19317.223
#159	XBP1	11	6	17	504.638
#160	FOSL1	11	10	21	1400.233
#161	HEYL	11	12	23	1198.251
#162	FOXC2	10	7	17	349.771
#163	DLX3	10	4	14	32.982
#164	HOXB7	10	5	15	475.302
#165	ZNF134	10	8	18	216.101
#166	NFATC1	10	6	16	75.081
#167	ATF2	10	11	21	9946.009
#168	EBF1	10	6	16	256.79
#169	DMTF1	10	9	19	495.283
#170	VAX2	10	8	18	1333.73
#171	HNRNPK	10	8	18	2842.497
#172	STRN3	10	7	17	1018.888
#173	BLZF1	10	5	15	4672.668
#174	ZSCAN22	9	7	16	1066.076
#175	MSRB2	9	9	18	563.97
#176	TSC22D1	9	10	19	1336.006
#177	ELF2	9	4	13	379.328
#178	ARID3A	9	9	18	428.96
#179	ZNF167	9	11	20	824.654
#180	HOXA4	9	7	16	424.306
#181	IRX1	9	5	14	91.162
#182	WNT5A	9	11	20	981.02
#183	MNX1	9	13	22	424.857
#184	HOXA5	9	7	16	43.935
#185	RFX5	9	13	22	1915.803
#186	MEIS2	9	8	17	370.808
#187	GCFC1	9	7	16	20113.114
#188	FOXJ2	9	9	18	2495.303
#189	ELF4	9	10	19	4698.937
#190	DLX2	9	12	21	7814.306
#191	CSDA	9	10	19	644.264
#192	SIX4	8	10	18	10178.784
#193	ETV6	8	8	16	212.779
#194	HMGA1	8	10	18	664.562
#195	SLC2A4RG	8	10	18	875.312
#196	PBX3	8	10	18	600.146
#197	ZFP36L1	8	9	17	1226.004
#198	HOXB9	8	9	17	3324.158
#199	STAT3	8	10	18	1728.29
#200	MBD1	8	8	16	584.344
#201	NFATC4	8	11	19	748.561
#202	PGBD1	8	11	19	570.415
#203	MAFK	8	10	18	365.861
#204	TCF7L2	8	10	18	507
#205	SMAD6	8	10	18	504.035
#206	TCEAL1	8	6	14	83.763
#207	ELF1	8	6	14	120.2
#208	HOXB3	8	5	13	96.376
#209	MMP14	8	7	15	300.573
#210	HES1	8	6	14	698.019
#211	KLF10	7	12	19	538.162
#212	GSX1	7	7	14	747.957
#213	IRF6	7	7	14	737.888
#214	TLX2	7	9	16	2926.831
#215	MAFF	7	11	18	646.654
#216	FOXN3	7	9	16	115.063
#217	NR3C1	7	5	12	249.23
#218	ZFP90	7	14	21	660.749
#219	SMAD2	7	10	17	5656.605
#220	ADNP	7	8	15	170.473
#221	SOX7	7	5	12	49.675
#222	ZNF281	7	12	19	822.246
#223	FOXF2	7	8	15	99.352
#224	FUBP1	7	12	19	1764.591
#225	STAT2	7	8	15	120.534
#226	ZNF85	7	8	15	222.887
#227	GRHL3	7	8	15	743.377
#228	POU2F3	7	14	21	8438.12
#229	FOXF1	7	7	14	999.976
#230	GABPB1	7	9	16	212.146
#231	VAV1	7	7	14	1044.727
#232	ZNF446	7	7	14	248.466
#233	TSC22D2	7	10	17	1941.227
#234	STAT4	6	8	14	1191.729
#235	RARB	6	8	14	563.401
#236	ZNF93	6	7	13	506.658
#237	RORC	6	13	19	4091.399
#238	FOSB	6	15	21	710.674
#239	KLF6	6	11	17	2412.694
#240	ZNF367	6	12	18	1978.517
#241	GATA4	6	11	17	431.403
#242	PURB	6	7	13	325.812
#243	NR3C2	6	7	13	89.795
#244	SATB1	6	7	13	478.956
#245	FOXA1	6	13	19	683.976
#246	SCML1	6	13	19	1903.729
#247	ZNF92	6	8	14	191.004
#248	CSRNP1	6	12	18	933.314
#249	IRF1	6	13	19	418.12
#250	CREBL2	6	12	18	195.592
#251	RFXAP	6	6	12	254.249
#252	ZRANB2	6	17	23	651.828
#253	MEIS3	6	12	18	327.213
#254	ZNF219	6	7	13	1442.572
#255	CNOT8	6	9	15	338.18
#256	RUNX3	6	10	16	459.667
#257	AFF1	6	11	17	602.375
#258	IRF3	6	8	14	1288.951
#259	RNF4	6	11	17	342.812
#260	TP53	6	10	16	1202.179
#261	PPARA	5	11	16	1872.366
#262	HSF2	5	8	13	190.266
#263	TSHZ1	5	9	14	1299.971
#264	HMGA2	5	7	12	450.993
#265	TAF4B	5	10	15	9390.609
#266	SUPT6H	5	9	14	1728.944
#267	NFYA	5	9	14	80.717
#268	EGR1	5	13	18	464.962
#269	CREBZF	5	12	17	183.798
#270	E2F7	5	10	15	348.441
#271	BATF3	5	11	16	1725.62
#272	NFYB	5	13	18	1357.519
#273	ZNF45	5	8	13	255.655
#274	RXRA	5	8	13	118.214
#275	DRAP1	5	10	15	119.629
#276	HIF1A	5	11	16	704.138
#277	FOS	5	9	14	56.177
#278	KLF9	5	13	18	3509.786
#279	CTNNB1	5	12	17	356.936
#280	MECOM	5	10	15	1362.707
#281	TCF19	5	13	18	506.818
#282	CEBPA	5	9	14	2823.408
#283	IRX3	5	8	13	80.094
#284	SIM2	5	11	16	774.095
#285	HMG20B	5	9	14	207.797
#286	NR0B1	5	8	13	2552.856
#287	FOXE1	5	10	15	101.526
#288	GATAD1	5	10	15	819.563
#289	NKX2-5	5	14	19	261.678
#290	BRD8	4	5	9	85.064
#291	ZNF132	4	11	15	236.633
#292	CREM	4	11	15	134.435
#293	ATF3	4	17	21	792.864
#294	KLF11	4	11	15	881.4
#295	CREB3L2	4	10	14	226.92
#296	ZBTB48	4	8	12	194.308
#297	SMAD3	4	8	12	100.076
#298	RBPJ	4	14	18	192.215
#299	LHX6	4	13	17	191.665
#300	ETV1	4	11	15	1195.779
#301	ZNF639	4	11	15	475.847
#302	ZIC1	4	6	10	47.739
#303	TAF5	4	11	15	205.132
#304	GLI2	4	6	10	291.003
#305	HOXB4	4	9	13	2816.393
#306	PBX4	4	12	16	433.561
#307	KDM5A	4	10	14	231.015
#308	UHRF1	4	12	16	282.523
#309	ZHX3	4	7	11	184.213
#310	TRIM22	4	11	15	281.255
#311	ARNT	4	9	13	285.393
#312	TAF12	4	10	14	126.312
#313	SMAD5	4	9	13	258.842
#314	ZNF83	4	12	16	447.091
#315	HR	4	8	12	1962.876
#316	EGR3	4	6	10	60.091
#317	POU6F1	4	6	10	40.22
#318	TFDP2	4	5	9	35.176
#319	TAF10	4	11	15	156.322
#320	TCF3	4	9	13	160.972
#321	SOX4	3	8	11	81.444
#322	SP3	3	8	11	335.63
#323	ZBTB25	3	8	11	120.754
#324	ZBTB38	3	8	11	35.888
#325	SATB2	3	5	8	27.503
#326	SNAI3	3	12	15	428.348
#327	MYT1	3	11	14	63.866
#328	FBXW7	3	6	9	161.273
#329	CBFB	3	8	11	32.081
#330	TAF5L	3	8	11	343.799
#331	ZNF274	3	10	13	85.615
#332	RERE	3	9	12	173.204
#333	ZNF91	3	15	18	7731.374
#334	SPEN	3	11	14	254.108
#335	FOXO6	3	11	14	435.717
#336	SOX17	3	3	6	13.097
#337	L3MBTL4	3	8	11	291.776
#338	IRF7	3	14	17	114.026
#339	GABPA	3	10	13	4077.427
#340	ZNF75D	3	6	9	381.572
#341	FOSL2	3	13	16	1189.277
#342	PCGF6	3	16	19	256.975
#343	IRX5	3	7	10	26.564
#344	CREB3L1	3	12	15	722.371
#345	BHLHE40	3	15	18	526.486
#346	FOXP2	3	2	5	10.999
#347	BTAF1	3	10	13	270.534
#348	MYBL2	3	12	15	415.37
#349	ZNF397	3	14	17	172.81
#350	RBCK1	3	10	13	181.443
#351	SP4	3	11	14	282.396
#352	BACH1	3	12	15	374.542
#353	KLF12	3	10	13	128.738
#354	TRIM29	3	13	16	433.263
#355	ZNF394	3	12	15	5653.433
#356	AFF4	3	10	13	2064.68
#357	ZIC2	3	6	9	457.703
#358	MAFB	3	12	15	325.179
#359	GSX2	3	7	10	7576.494
#360	ATF1	3	10	13	1891.385
#361	TARDBP	3	11	14	367.71
#362	LHX1	3	11	14	115.874
#363	MITF	2	9	11	1852.969
#364	TSHZ3	2	10	12	301.286
#365	SOX8	2	8	10	74.949
#366	ZNF148	2	12	14	1813
#367	NFKB1	2	10	12	188.996
#368	ZSCAN16	2	17	19	153.481
#369	MXD1	2	9	11	120.257
#370	SOX11	2	8	10	306.46
#371	TBX1	2	10	12	50.014
#372	EGR2	2	9	11	280.278
#373	ZNF277	2	13	15	187.525
#374	LCOR	2	8	10	14.48
#375	ZNF256	2	12	14	104.735
#376	FOXO3	2	10	12	45.211
#377	TP73	2	9	11	38.809
#378	HOXC11	2	12	14	204.361
#379	SOX9	2	14	16	178.586
#380	ZNF18	2	10	12	872.621
#381	SCAND2	2	7	9	62.937
#382	ZC3H8	2	8	10	213.857
#383	CIR1	2	9	11	88.858
#384	SIX5	2	10	12	104.833
#385	E2F4	2	9	11	421.622
#386	C2orf3	2	6	8	64.672
#387	IRX4	2	9	11	285.7
#388	HLF	2	7	9	150.319
#389	MTA1	2	7	9	206.292
#390	HOXA11	2	8	10	57.462
#391	THRA	2	10	12	54.138
#392	TSC22D3	2	9	11	131.645
#393	NFAT5	2	6	8	181.699
#394	NFIC	2	9	11	135.183
#395	ELK4	2	9	11	781.783
#396	ZNF19	2	7	9	25.756
#397	ZKSCAN3	2	14	16	278.179
#398	HDAC2	2	8	10	1421.061
#399	ELK1	2	9	11	42.881
#400	ZKSCAN5	2	11	13	111.261
#401	E2F3	2	11	13	79.221
#402	TFAP2B	2	11	13	220.685
#403	TFAP2A	2	6	8	40.725
#404	MNT	2	8	10	130.734
#405	ZFHX2	2	8	10	45.382
#406	DLX4	2	10	12	71.881
#407	IKZF4	2	11	13	87.194
#408	GATA2	2	8	10	1674.785
#409	NKX3-1	2	18	20	577.624
#410	SLC30A9	2	14	16	102.398
#411	E2F5	2	10	12	63.217
#412	ZNF496	1	10	11	23.407
#413	NFATC2	1	12	13	51.479
#414	IRX2	1	12	13	24.708
#415	NR4A2	1	11	12	393.271
#416	KLF3	1	15	16	63.452
#417	VENTX	1	12	13	71.544
#418	LHX3	1	9	10	16.336
#419	AHR	1	12	13	14.77
#420	PHTF1	1	11	12	69.584
#421	ETV4	1	15	16	17.518
#422	ZNF449	1	13	14	145.28
#423	HOXA9	1	6	7	59.272
#424	PRDM1	1	4	5	16.85
#425	PITX1	1	14	15	157.631
#426	ZNF70	1	11	12	60.146
#427	ZFP36L2	1	13	14	123.421
#428	C11orf9	1	9	10	55.882
#429	SIN3A	1	9	10	169.051
#430	WT1	1	8	9	19.556
#431	SPIB	1	9	10	14.691
#432	ZNF3	1	5	6	7.338
#433	ESR1	1	6	7	8.933
#434	MEIS3P1	1	14	15	94.794
#435	NFXL1	1	15	16	95.226
#436	JUN	1	18	19	64.223
#437	DBP	1	12	13	127.382
#438	SOX12	1	12	13	20.161
#439	CITED2	1	16	17	104.422
#440	TFDP1	1	14	15	38.806
#441	ARNT2	1	6	7	7.762
#442	SOX6	1	12	13	134.914
#443	NFE2L2	1	11	12	70.022
#444	NR4A3	1	6	7	19.742
#445	NR2C1	1	11	12	1202.613
#446	CCRN4L	1	8	9	71.84
#447	YY1	1	10	11	553.436
#448	C5orf41	1	12	13	110.524
#449	KLF5	1	14	15	60.2
#450	MYCN	1	11	12	32.858
#451	CSRNP2	1	14	15	39.933
#452	BCL3	1	12	13	95.598
#453	ATF6	1	11	12	64.279
#454	HAND1	1	8	9	95.426
#455	BCL6	1	15	16	53.448
#456	BTG2	0	12	12	0
#457	ZNF202	0	9	9	0
#458	NFATC3	0	10	10	0
#459	VTN	0	7	7	0
#460	ZNF628	0	11	11	0
#461	RELB	0	18	18	0
#462	ZNF207	0	10	10	0
#463	HOXD8	0	11	11	0
#464	HMGB2	0	15	15	0
#465	HOXB8	0	5	5	0
#466	TULP4	0	14	14	0
#467	HOXD10	0	7	7	0
#468	ZNF165	0	13	13	0
#469	ZNF445	0	9	9	0
#470	ZNF37A	0	7	7	0
#471	ZNF438	0	11	11	0
#472	E2F8	0	12	12	0
#473	NR4A1	0	12	12	0
#474	SIX3	0	7	7	0
#475	JUNB	0	15	15	0
#476	IRF9	0	9	9	0
#477	MAX	0	13	13	0
#478	GATA5	0	14	14	0
#479	KLF2	0	14	14	0
#480	THRB	0	11	11	0
#481	ELF5	0	7	7	0
#482	FOXP4	0	14	14	0
#483	REL	0	7	7	0
#484	KLF4	0	14	14	0
#485	ZNF187	0	8	8	0
#486	NFX1	0	8	8	0
#487	EN1	0	11	11	0
#488	KLF7	0	17	17	0
#489	ENO1	0	9	9	0
#490	ZNF174	0	8	8	0
#491	CEBPD	0	8	8	0
#492	ARID4A	0	9	9	0
#493	ARNTL	0	9	9	0
#494	TADA2A	0	11	11	0
#495	CBL	0	7	7	0
#496	ZNF138	0	12	12	0
#497	MYC	0	14	14	0
#498	EGR4	0	11	11	0
#499	GATAD2B	0	11	11	0
#500	C12orf28	0	9	9	0