Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	YBX1	33	4	37	1415.607
#2	ZFPM2	32	10	42	3049.878
#3	NR2F2	32	9	41	922.644
#4	ENO1	31	5	36	915.017
#5	TCF3	30	7	37	1143.642
#6	MEF2C	30	6	36	955.086
#7	HMGB1	29	4	33	1847.281
#8	BCL6	28	6	34	736.173
#9	TCFL5	27	6	33	921.514
#10	BTG2	27	5	32	465.039
#11	YEATS4	27	7	34	1164.713
#12	MLLT10	26	8	34	2166.716
#13	STAT3	26	8	34	880.407
#14	IRF8	25	9	34	1200.049
#15	C11orf9	25	4	29	276.048
#16	HMGB2	25	7	32	1172.944
#17	SMAD4	24	8	32	935.016
#18	KLF6	24	11	35	1499.201
#19	EGR2	24	5	29	1334.784
#20	NFYC	24	8	32	2893.453
#21	KLF2	24	7	31	607.759
#22	HOXB3	24	7	31	2539.137
#23	CUX1	23	10	33	1614.179
#24	MAFB	23	6	29	753.13
#25	MLX	23	6	29	784.946
#26	ZNF394	23	9	32	2499.656
#27	PPARA	22	7	29	1887.151
#28	CBFA2T3	22	10	32	1964.156
#29	GTF2H3	22	9	31	4693.007
#30	LEF1	22	4	26	557.201
#31	TRIM28	22	4	26	560.281
#32	GATAD1	21	15	36	2209.164
#33	WT1	21	9	30	561.936
#34	NFIB	21	8	29	973.316
#35	MEIS2	21	1	22	73.104
#36	TFE3	21	9	30	1224.207
#37	NR4A1	21	2	23	286.94
#38	CREB1	20	13	33	2657.115
#39	ATF2	20	8	28	2255.502
#40	SLC2A4RG	20	12	32	2518.347
#41	GATA6	20	5	25	425.379
#42	EGR1	20	3	23	486.002
#43	TEAD4	20	12	32	1287.888
#44	NR4A2	20	6	26	463.073
#45	TSHZ2	20	9	29	1929.28
#46	BHLHE40	19	8	27	1192.045
#47	ELK4	19	10	29	2916.084
#48	CSDA	19	4	23	481.786
#49	ZNF3	19	10	29	1348.669
#50	TP73	19	8	27	1331.024
#51	IRF2	19	11	30	2552.036
#52	ZNF45	19	10	29	1573.418
#53	TGIF2	18	9	27	928.547
#54	NFYB	18	12	30	1478.14
#55	BLZF1	18	10	28	1541.775
#56	BNC1	18	9	27	1590.419
#57	CNOT8	18	8	26	2125.194
#58	ZNF91	18	10	28	1359.684
#59	EGR3	18	2	20	56.466
#60	HOPX	18	10	28	1159.565
#61	MSRB2	17	10	27	1150.384
#62	ZGPAT	17	14	31	2903.55
#63	MAFF	17	11	28	1349.799
#64	REST	17	11	28	1087.747
#65	AEBP1	17	10	27	1720.495
#66	ZNF446	17	6	23	1013.836
#67	NEUROG1	17	13	30	4207.204
#68	PBX1	16	12	28	1812.54
#69	ASCL1	16	9	25	2844.768
#70	HMGA1	16	9	25	1385.637
#71	DLX6	16	12	28	1400.611
#72	ZNF24	16	7	23	1110.763
#73	TBX6	16	11	27	1904.98
#74	SOX17	16	13	29	2114.219
#75	C2orf3	16	8	24	892.934
#76	KLF12	16	7	23	1145.703
#77	FOXM1	16	10	26	692.554
#78	SPIB	16	8	24	1717.866
#79	ZNF81	16	13	29	2347.902
#80	E2F3	16	14	30	1833.506
#81	TCF7L2	16	8	24	1993.137
#82	HOXD9	16	13	29	2151.343
#83	MYC	16	9	25	1346.047
#84	LZTS1	15	12	27	2071.422
#85	IKZF1	15	7	22	1014.561
#86	MTF1	15	12	27	1729.301
#87	ZSCAN16	15	11	26	2787.31
#88	ELF5	15	11	26	2310.962
#89	PLAGL2	15	12	27	994.541
#90	E2F6	15	12	27	1122.447
#91	HINFP	15	10	25	1621.978
#92	DRAP1	15	8	23	1319.546
#93	NR4A3	15	4	19	155.587
#94	VTN	15	7	22	848.72
#95	NFATC3	15	12	27	1284.071
#96	MSX1	15	10	25	1810
#97	CREM	15	8	23	904.794
#98	AHR	15	11	26	1561.19
#99	BATF	15	12	27	2290.625
#100	EVX1	15	8	23	866.935
#101	FOXN2	15	11	26	1898.923
#102	ATF6B	15	8	23	1817.206
#103	NFATC1	15	11	26	1986.925
#104	GCM1	15	6	21	1799.562
#105	SNAI2	15	14	29	1919.631
#106	TFDP1	15	9	24	803.726
#107	EPAS1	15	7	22	1336.87
#108	FOS	15	12	27	3820.995
#109	EMX1	15	14	29	1657.767
#110	SCML1	15	8	23	2707.912
#111	ZFP37	14	10	24	954.319
#112	NFKB2	14	14	28	1504.727
#113	TP53	14	9	23	1901.576
#114	TBX10	14	11	25	2544.785
#115	ARID3A	14	11	25	3038.278
#116	HSF1	14	8	22	1467.382
#117	MYF6	14	8	22	1339.394
#118	HOXA1	14	9	23	903.706
#119	ONECUT1	14	15	29	1772.161
#120	ZKSCAN1	14	10	24	1573.433
#121	FOXD1	14	11	25	1490.849
#122	FOXO1	13	10	23	976.597
#123	LHX1	13	12	25	1544.812
#124	ZHX2	13	8	21	1716.972
#125	GAS7	13	11	24	1159.29
#126	PBX3	13	6	19	784.251
#127	ZNF193	13	12	25	1145.673
#128	OLIG2	13	8	21	1301.36
#129	PLSCR1	13	8	21	1481.217
#130	FOSL1	13	7	20	1419.907
#131	SOX2	13	10	23	1395.79
#132	PROX1	13	8	21	1271.067
#133	JUNB	13	10	23	1117.481
#134	ETS2	13	9	22	1401.183
#135	ZNF117	13	12	25	1234.021
#136	ELK3	13	10	23	1162.724
#137	NKX2-5	12	11	23	1272.04
#138	PHTF1	12	7	19	654.562
#139	MEF2A	12	9	21	658.205
#140	ZNF80	12	12	24	2403.266
#141	ZNF192	12	8	20	796.88
#142	TRIM29	12	13	25	2765.138
#143	TCF4	12	8	20	525.59
#144	TAF1B	12	11	23	1378.038
#145	RFXAP	12	9	21	1164.439
#146	HOXD12	12	7	19	1440.966
#147	SIX1	12	15	27	1919.003
#148	ZNF41	12	8	20	1319.319
#149	KLF4	12	5	17	922.029
#150	PITX2	12	12	24	2366.309
#151	DMRT1	12	14	26	1720.474
#152	ERG	12	11	23	2260.319
#153	FOSB	12	5	17	1235.102
#154	TADA3	12	8	20	1166.322
#155	RFX5	12	5	17	342.652
#156	ADNP2	12	11	23	1497.697
#157	FOXI1	12	7	19	1241.815
#158	GABPA	12	7	19	756.605
#159	ETV1	12	11	23	877.039
#160	HNF4A	12	9	21	855.561
#161	NR1H4	12	11	23	2292.634
#162	HOXB1	12	8	20	478.464
#163	NR2F1	12	8	20	1012.551
#164	ELF2	12	8	20	419.238
#165	ONECUT2	12	10	22	1191.366
#166	HMBOX1	12	11	23	1365.841
#167	PCGF2	12	11	23	1110.862
#168	TFEC	11	7	18	349.785
#169	HIRA	11	5	16	202.29
#170	RBCK1	11	13	24	2182.701
#171	TFDP2	11	13	24	2147.447
#172	TFEB	11	6	17	319.274
#173	HNF1B	11	9	20	1331.191
#174	NR5A1	11	12	23	1432.628
#175	T	11	8	19	556.29
#176	SP140	11	12	23	921.726
#177	HAND2	11	11	22	1218.757
#178	OVOL1	11	8	19	764.25
#179	NKX2-1	11	11	22	880.145
#180	SUPT6H	11	11	22	1296.393
#181	ZNF131	11	8	19	899.247
#182	ZNF167	11	5	16	294.479
#183	HOXB8	11	7	18	905.952
#184	KLF5	11	12	23	1690.477
#185	ZNF434	11	9	20	1269.184
#186	ATF6	11	13	24	1000.047
#187	ELF3	11	11	22	1769.616
#188	POU3F1	11	8	19	858.697
#189	NR2C1	11	10	21	1358.325
#190	RARA	11	13	24	2272.636
#191	MYOD1	11	10	21	1760.102
#192	HOXA4	11	10	21	1168.902
#193	DBP	11	12	23	2275.372
#194	EN1	10	9	19	1178.367
#195	CTBP1	10	10	20	890.142
#196	ETV2	10	10	20	1108.896
#197	HMX1	10	8	18	416.982
#198	ZFP36L1	10	13	23	1057.027
#199	NFATC4	10	11	21	1179.155
#200	RFX3	10	8	18	723.12
#201	SOLH	10	4	14	458.48
#202	MAX	10	11	21	742.212
#203	TCF21	10	9	19	657.994
#204	VSX1	10	10	20	979.815
#205	TLX3	10	8	18	2052.257
#206	MYBL2	10	11	21	924.703
#207	CBFB	10	15	25	1068.224
#208	PAX4	10	13	23	2099.057
#209	CDKN2A	10	11	21	1696.336
#210	ZNF155	10	13	23	1695.391
#211	NEUROD1	10	11	21	1107.475
#212	POU3F2	10	10	20	1755.585
#213	SPEN	10	10	20	1108.392
#214	HOXA7	10	9	19	962.601
#215	CEBPA	10	8	18	706.828
#216	PBX2	10	6	16	775.607
#217	FOSL2	10	9	19	587.479
#218	ELF1	10	11	21	745.736
#219	AFF1	10	13	23	1142.429
#220	ZNF202	10	9	19	914.888
#221	ATF3	10	4	14	174.987
#222	SATB2	10	10	20	847.676
#223	RFXANK	10	16	26	995.843
#224	STAT1	10	8	18	489.896
#225	FOXA2	10	9	19	1332.6
#226	PAX3	10	10	20	896.808
#227	HOXD3	10	8	18	846.286
#228	SREBF1	9	5	14	368.763
#229	MSX2	9	8	17	1305.387
#230	MAF	9	11	20	909.26
#231	TCF12	9	12	21	1107.17
#232	HOXC8	9	9	18	742.4
#233	CREB5	9	11	20	1325.868
#234	RCAN1	9	11	20	1261.405
#235	LMO4	9	9	18	990.457
#236	MEOX2	9	7	16	179.838
#237	ZFHX4	9	8	17	557.606
#238	CREB3	9	12	21	746.221
#239	RUNX1	9	12	21	917.325
#240	SALL1	9	9	18	875.367
#241	RAX	9	7	16	470.614
#242	GATA1	9	9	18	846.792
#243	RB1	9	14	23	2454.776
#244	FOXJ1	9	8	17	873.181
#245	ZNF135	9	9	18	792.485
#246	MYF5	9	13	22	1145.082
#247	CITED2	9	7	16	453.505
#248	UBN1	9	12	21	1046.32
#249	FOXH1	9	11	20	1371.384
#250	TFAP2A	9	10	19	1374.501
#251	TFAM	9	16	25	1167.323
#252	GTF2H4	9	7	16	969.329
#253	PPARG	9	9	18	417.849
#254	PHOX2A	9	11	20	1349.727
#255	REXO4	9	13	22	1258.433
#256	SIM1	9	15	24	1118.973
#257	KDM5A	9	5	14	915.339
#258	RERE	9	11	20	1773
#259	MECOM	9	13	22	1367.531
#260	ATF5	9	12	21	767.216
#261	HLF	9	13	22	741.473
#262	NFIX	9	7	16	710.108
#263	HOXA6	9	14	23	1577.762
#264	TWIST1	9	10	19	530.023
#265	HOXD11	9	9	18	1136.547
#266	FOXL2	9	9	18	1063.598
#267	ALX4	9	9	18	978.653
#268	MYCL1	9	8	17	1100.503
#269	TCF25	9	10	19	931.425
#270	E4F1	9	10	19	883.362
#271	GATA2	9	10	19	779.065
#272	TFDP3	8	5	13	870.361
#273	NR1I2	8	9	17	841.929
#274	ZEB1	8	14	22	1125.883
#275	ZNF444	8	13	21	1587.337
#276	ECSIT	8	10	18	1196.649
#277	NRL	8	6	14	952.93
#278	HOXA3	8	9	17	729.275
#279	RUNX3	8	13	21	1328.875
#280	SP1	8	15	23	2035.353
#281	ZFP36L2	8	13	21	1366.29
#282	NPAS2	8	14	22	1242.798
#283	SIM2	8	11	19	1001.317
#284	SPDEF	8	7	15	1017.796
#285	DLX2	8	15	23	1502.025
#286	SOX11	8	13	21	1093.534
#287	ZNF643	8	12	20	1141.533
#288	KLF9	8	7	15	1133.664
#289	SMAD5	8	15	23	2057.754
#290	POU5F1B	8	8	16	465.666
#291	ZIC3	8	13	21	1534.01
#292	ZNF287	8	13	21	1738.805
#293	TEF	8	9	17	833.902
#294	EGR4	8	11	19	1344.158
#295	ZNF639	8	13	21	1082.467
#296	STAT2	8	8	16	992.951
#297	ISL1	8	10	18	584.017
#298	ZNF236	8	13	21	1509.041
#299	CBFA2T2	8	10	18	904.404
#300	ETV6	8	12	20	909.413
#301	ZFHX3	8	14	22	1912.217
#302	GABPB1	8	12	20	1356.463
#303	SOX30	8	6	14	961.499
#304	CUX2	8	13	21	1523.698
#305	IRF3	8	11	19	1161.347
#306	MEF2D	8	11	19	707.866
#307	ZNF154	8	10	18	1294.292
#308	HES1	8	11	19	1299.645
#309	NR5A2	8	13	21	2318.338
#310	SREBF2	8	8	16	774.983
#311	NFYA	8	11	19	651.167
#312	MXD1	8	8	16	699.729
#313	SRF	8	12	20	1287.11
#314	CREBBP	8	15	23	1222.862
#315	TP63	8	9	17	902.397
#316	RARG	8	12	20	1208.332
#317	POU6F1	8	11	19	880.999
#318	MLXIPL	8	12	20	775.836
#319	MEOX1	8	10	18	856.05
#320	NR2F6	8	16	24	1221.593
#321	IRX5	7	10	17	789.014
#322	WNT5A	7	15	22	1529.939
#323	FOXD2	7	11	18	982.852
#324	IRF7	7	11	18	359.656
#325	PHOX2B	7	14	21	1859.863
#326	ESRRG	7	11	18	626.674
#327	PAX7	7	8	15	359.535
#328	TAL1	7	12	19	767.587
#329	JUN	7	10	17	436.177
#330	TBX3	7	11	18	549.548
#331	VDR	7	13	20	647.798
#332	CSRNP3	7	11	18	1035.114
#333	ARNTL2	7	13	20	811.382
#334	ZBTB48	7	16	23	1092.654
#335	ETV4	7	9	16	915.775
#336	SOX18	7	11	18	970.029
#337	FOXC2	7	8	15	517.533
#338	MZF1	7	14	21	833.133
#339	PRDM2	7	11	18	1019.11
#340	MYCN	7	12	19	898.859
#341	PITX1	7	9	16	1213.887
#342	POU4F1	7	10	17	911
#343	E2F5	7	13	20	611.218
#344	AR	7	9	16	883.522
#345	BHLHE41	7	13	20	1351.797
#346	NR0B1	7	12	19	742.118
#347	IRF4	7	10	17	1209.457
#348	NPAS1	7	8	15	452.837
#349	ELK1	7	12	19	754.806
#350	TBX2	7	11	18	1164.502
#351	HOXD13	7	10	17	784.001
#352	SOX15	7	9	16	629.005
#353	NFIC	6	12	18	1314.409
#354	GATA3	6	13	19	936.632
#355	E2F8	6	14	20	669.498
#356	SMAD6	6	17	23	934.798
#357	HMG20B	6	17	23	956.384
#358	NR3C2	6	15	21	1165.992
#359	GATA4	6	13	19	703.707
#360	SLC26A3	6	12	18	780.951
#361	TSC22D2	6	11	17	916.151
#362	NFE2	6	8	14	599.084
#363	FOXE1	6	10	16	1146.671
#364	ARNTL	6	13	19	612.178
#365	SMAD1	6	15	21	1135.99
#366	NFX1	6	12	18	1470.062
#367	CREBZF	6	12	18	684.524
#368	HEY1	6	13	19	855.945
#369	SMAD3	6	15	21	834.971
#370	TAF12	6	18	24	1507.16
#371	SRY	6	10	16	690.016
#372	RARB	6	16	22	2099.547
#373	KDM5B	6	13	19	963.336
#374	SNAPC5	6	15	21	990.865
#375	ALS2CR8	6	9	15	839.324
#376	RORA	6	8	14	778.795
#377	BRD8	6	14	20	437.915
#378	HOXD1	6	9	15	707.605
#379	LHX6	6	14	20	687.306
#380	RXRB	6	10	16	804.833
#381	SIX3	6	15	21	1249.653
#382	NKX3-2	6	12	18	890.273
#383	HEY2	6	7	13	538.152
#384	TAF5	6	11	17	1136.203
#385	PDX1	6	9	15	530.031
#386	KLF15	6	9	15	320.796
#387	ERF	6	12	18	543.932
#388	NFAT5	6	6	12	737.586
#389	ZNF93	6	6	12	330.925
#390	ARNT	6	16	22	1369.711
#391	TSC22D3	6	10	16	660.967
#392	POU3F3	6	8	14	545.745
#393	HIC1	6	9	15	694.447
#394	FOXO3	6	7	13	546.111
#395	SPI1	6	11	17	697.714
#396	TADA2A	6	14	20	989.491
#397	TCF15	6	9	15	604.9
#398	ZNF174	6	7	13	102.695
#399	ESR1	5	10	15	1005.696
#400	ASCL2	5	7	12	699.534
#401	TEAD1	5	11	16	957.361
#402	SOX21	5	16	21	1544.339
#403	ZNF134	5	12	17	948.214
#404	THRA	5	13	18	1034.782
#405	MNX1	5	9	14	498.176
#406	MMP14	5	13	18	776.702
#407	RELB	5	14	19	1245.841
#408	TFAP2B	5	10	15	449.71
#409	HESX1	5	8	13	789.818
#410	EN2	5	10	15	791.171
#411	ESR2	5	16	21	1189.31
#412	FOXN3	5	14	19	777.607
#413	HOXB7	5	14	19	682.06
#414	SOX13	5	12	17	693.913
#415	REL	5	11	16	1014.388
#416	PKNOX1	5	11	16	978.097
#417	NR6A1	5	9	14	313.916
#418	STAT6	5	7	12	349.429
#419	LHX2	5	11	16	697.328
#420	PPARD	5	13	18	1115.629
#421	PAX6	5	8	13	866.075
#422	POU4F3	5	12	17	1141.544
#423	CREB3L1	5	10	15	515.126
#424	PTH	5	14	19	928.889
#425	SOX4	5	17	22	1140.145
#426	HOXA9	5	13	18	1007.479
#427	HOXA10	5	14	19	1039.766
#428	PPBPL2	5	10	15	452.032
#429	ZHX3	5	10	15	819.051
#430	RELA	5	10	15	663.735
#431	TBX19	5	11	16	755.027
#432	HOXB6	5	11	16	834.229
#433	ZSCAN18	5	8	13	789.597
#434	POU3F4	5	12	17	798.824
#435	MGA	5	8	13	424.891
#436	E2F4	5	14	19	987.979
#437	HIF3A	5	12	17	846.01
#438	VAX2	5	9	14	422.999
#439	BATF3	5	12	17	894.324
#440	ZNF323	5	9	14	490.875
#441	ELF4	5	8	13	579.23
#442	PAX8	5	12	17	550.162
#443	SOX9	4	9	13	374.84
#444	TBX1	4	11	15	448.399
#445	SCAND2	4	11	15	665.36
#446	PGR	4	9	13	200.075
#447	JUND	4	21	25	1510.502
#448	CEBPE	4	16	20	663.188
#449	FOXP3	4	12	16	852.023
#450	BCL3	4	12	16	544.826
#451	ZNF157	4	10	14	462.41
#452	TFCP2	4	11	15	268.739
#453	ETV5	4	9	13	489.632
#454	ARNT2	4	12	16	729.838
#455	PLAG1	4	13	17	480.992
#456	HNF1A	4	11	15	670.726
#457	MYT1	4	13	17	711.688
#458	GBX2	4	13	17	599.689
#459	POU2F3	4	9	13	283.686
#460	HNF4G	4	10	14	594.501
#461	NR1H2	4	8	12	347.575
#462	ZNF165	4	14	18	639.183
#463	RUNX1T1	4	13	17	480.643
#464	STRN3	4	16	20	1459.972
#465	ZNF238	4	10	14	367.359
#466	GLI2	4	9	13	451.283
#467	TLX2	4	11	15	497.892
#468	MLL	4	16	20	809.864
#469	FOXF1	3	11	14	436.854
#470	IKZF3	3	12	15	666.133
#471	MYT1L	3	9	12	250.309
#472	FOXD3	3	11	14	360.83
#473	SATB1	3	9	12	459.664
#474	TBX5	3	12	15	459.558
#475	BARX1	3	14	17	418.192
#476	MSC	3	15	18	926.357
#477	MAFK	3	9	12	320.844
#478	FOXO4	3	13	16	732.266
#479	ZIC1	3	17	20	901.026
#480	EHF	3	13	16	621.813
#481	GSC2	3	11	14	734.177
#482	HOXA2	3	16	19	363.355
#483	FOXG1	3	15	18	420.87
#484	HOXC13	3	14	17	439.446
#485	POU1F1	3	12	15	404.882
#486	CRX	3	11	14	218.3
#487	SCRT1	2	11	13	301.619
#488	ETS1	2	11	13	191.499
#489	ALX3	2	13	15	386.751
#490	RXRA	2	16	18	940.69
#491	USF2	2	13	15	290.756
#492	ZNF215	2	13	15	572.323
#493	GATAD2A	2	12	14	427.678
#494	TFAP2C	2	14	16	376.394
#495	ZXDC	2	12	14	160.753
#496	PAX5	2	11	13	234.84
#497	NPAT	1	5	6	27.433
#498	TAF13	1	11	12	76.482
#499	NKX2-8	1	15	16	100.721
#500	ATOH1	0	9	9	0