Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TFDP2	54	0	54	0
#2	GRHL3	47	2	49	32.85
#3	TCF7L2	46	9	55	460.245
#4	TFE3	45	3	48	70.89
#5	THRA	44	4	48	372.973
#6	ATOH1	44	3	47	546.229
#7	NFYC	43	8	51	251.882
#8	LHX6	40	10	50	925.637
#9	SPDEF	39	14	53	927.313
#10	KLF12	38	5	43	557.314
#11	C11orf9	38	5	43	1138.837
#12	RELA	38	1	39	5.684
#13	ZSCAN29	37	9	46	1122.308
#14	MYOG	37	8	45	764.591
#15	ETV4	37	3	40	176.108
#16	MMP14	37	8	45	3504.821
#17	TCF3	37	9	46	536.962
#18	ELF5	36	4	40	7244.756
#19	HOXB6	36	10	46	1244.56
#20	PURB	35	7	42	200.099
#21	MYT1L	35	6	41	543.588
#22	TBX5	35	4	39	36.672
#23	HOXB3	34	7	41	725.233
#24	FOXP2	34	10	44	1752.197
#25	SP1	34	10	44	794.679
#26	PBX3	34	4	38	241.671
#27	NFAT5	33	7	40	4008.184
#28	ZNF219	33	7	40	670.12
#29	GSC2	33	7	40	3043.198
#30	RUNX2	33	12	45	3406.485
#31	CSRNP3	32	5	37	187.75
#32	NFYB	32	16	48	3746.552
#33	ZNF189	32	9	41	1019.158
#34	ATF2	32	9	41	2535.123
#35	TP53	31	11	42	404.328
#36	SP4	31	4	35	1514.779
#37	MAFK	31	9	40	918.583
#38	DMTF1	31	8	39	2005.429
#39	EOMES	30	6	36	2205.386
#40	CREBL2	30	8	38	1413.541
#41	ASCL2	29	7	36	512.451
#42	POU4F2	29	10	39	1106.434
#43	E2F2	29	6	35	385.875
#44	PRDM1	29	9	38	981.84
#45	ELK4	29	13	42	4585.666
#46	POU3F2	28	9	37	915.088
#47	PHF1	28	5	33	442.17
#48	AFF1	28	11	39	812.459
#49	ZNF263	28	11	39	1045.662
#50	RB1	27	12	39	1442.998
#51	ZNF236	27	9	36	1639.536
#52	TMEM229A	27	4	31	885.176
#53	MBD1	27	7	34	1244.334
#54	SMAD1	27	7	34	587.465
#55	C5orf41	27	7	34	2546.969
#56	ESX1	27	9	36	1297.365
#57	L3MBTL4	27	11	38	833.77
#58	NR1H2	26	9	35	1178.684
#59	FOXI1	26	3	29	435.844
#60	CUX1	26	6	32	928.073
#61	POU6F2	26	12	38	597.777
#62	RAX	26	8	34	832.719
#63	ARX	26	14	40	9412.926
#64	NKX6-1	25	8	33	311.981
#65	CSDA	25	8	33	640.115
#66	ETV3	25	9	34	5318.346
#67	HOXB7	25	6	31	1880.046
#68	MLLT10	25	16	41	3922.364
#69	ALX4	25	3	28	284.164
#70	CCRN4L	25	7	32	3654.503
#71	SMAD5	24	11	35	352.398
#72	AHCTF1	24	10	34	518.187
#73	ESR2	24	15	39	1174.319
#74	ZFHX4	24	5	29	403.589
#75	HSF2	24	15	39	4537.966
#76	UHRF1	24	16	40	3420.533
#77	ZFP42	24	12	36	4461.683
#78	ATF3	24	12	36	538.959
#79	TSC22D2	24	4	28	125.257
#80	MITF	24	12	36	1942.395
#81	STAT6	24	15	39	4529.764
#82	ADNP2	23	5	28	749.476
#83	MAFA	23	14	37	2136.616
#84	TEF	23	10	33	4733.174
#85	ZBTB48	23	2	25	6.947
#86	SMAD4	23	10	33	859.085
#87	RUNX1	23	8	31	1020.626
#88	FOXK1	23	9	32	5904.067
#89	IRF4	23	14	37	2277.33
#90	DMRT1	23	7	30	550.947
#91	CREM	23	12	35	4873.715
#92	TULP4	23	16	39	1541.772
#93	POU3F4	23	7	30	224.188
#94	GATA2	23	14	37	1966.887
#95	OTX1	23	13	36	494.863
#96	BATF3	23	10	33	878.928
#97	RCOR2	22	18	40	2951.839
#98	DDIT3	22	10	32	801.659
#99	SOX8	22	14	36	405.873
#100	CDKN2A	22	5	27	425.046
#101	ZNF232	22	8	30	2958.388
#102	ZNF148	22	9	31	3506.705
#103	SUPT6H	22	12	34	914.993
#104	FOXL1	22	15	37	11834.477
#105	SOX10	22	10	32	929.949
#106	NFE2L1	21	14	35	1705.548
#107	GABPB1	21	16	37	2380.554
#108	RBPJ	21	21	42	4957.059
#109	FOXA3	21	7	28	1351.083
#110	CNOT7	21	12	33	493.937
#111	PKNOX2	21	16	37	2501.858
#112	IKZF4	21	14	35	2912.843
#113	MXD1	21	16	37	2921.557
#114	SALL2	21	18	39	3094.682
#115	CREB3L3	20	11	31	1228.379
#116	HMGB1	20	15	35	705.51
#117	FOXD1	20	10	30	813.842
#118	CREB1	20	15	35	1223.802
#119	FLI1	20	17	37	1889.545
#120	HMGA2	20	11	31	492.265
#121	MLL	20	21	41	6049.942
#122	NFIX	20	12	32	662.295
#123	NR0B1	19	10	29	438.669
#124	PPARD	19	7	26	418.43
#125	NOLC1	19	10	29	859.726
#126	CEBPB	19	14	33	928.422
#127	RARG	19	15	34	871.246
#128	HMGA1	19	14	33	3340.021
#129	USF2	19	14	33	4132.086
#130	PPARG	19	16	35	2302.131
#131	IRF5	19	7	26	478.848
#132	TBX1	19	22	41	2487.596
#133	ZNF19	19	12	31	6630.203
#134	ZNF438	19	19	38	3335.938
#135	HIF1A	19	13	32	2397.63
#136	MYPOP	19	11	30	946.274
#137	ZNF643	19	9	28	2421.301
#138	HOXC6	19	15	34	3066.116
#139	GATA4	18	17	35	1820.51
#140	FOXD3	18	13	31	1771.82
#141	FOXQ1	18	8	26	713.43
#142	MNT	18	20	38	3843.101
#143	LZTR1	18	14	32	2351.22
#144	BATF2	18	11	29	1058.215
#145	SMAD9	18	18	36	818.741
#146	VTN	18	2	20	49.111
#147	CNOT8	18	6	24	590.268
#148	ZSCAN20	18	15	33	490.278
#149	HOXA4	18	14	32	2031.481
#150	ZNF165	18	14	32	8365.424
#151	ZNF238	17	12	29	2090.902
#152	TFDP1	17	18	35	2508.337
#153	TBX4	17	8	25	888.771
#154	RFXANK	17	10	27	4571.586
#155	SOX30	17	17	34	1521.885
#156	FOXA2	17	7	24	152.567
#157	MEOX2	17	5	22	410.934
#158	MYBL2	17	6	23	626.317
#159	SCAND3	17	5	22	254.446
#160	NOTCH1	16	11	27	226.673
#161	FUBP1	16	17	33	2176.463
#162	TBX19	16	16	32	2072.03
#163	VDR	16	18	34	9945.672
#164	FOXE1	16	21	37	1551.306
#165	LASS5	16	7	23	1104.961
#166	TCF7	16	14	30	524.182
#167	EMX1	16	12	28	919.7
#168	ZNF500	16	9	25	1259.799
#169	KCNH8	16	12	28	892.287
#170	PKNOX1	16	12	28	741.934
#171	STAT1	16	15	31	736.596
#172	PLAGL2	16	10	26	542.741
#173	DLX2	16	13	29	563.611
#174	NR1D2	15	10	25	1042.167
#175	HESX1	15	11	26	298.923
#176	ETV6	15	20	35	4747.696
#177	MECOM	15	4	19	316.764
#178	SOX9	15	12	27	739.448
#179	ZKSCAN4	15	14	29	4370.51
#180	ETV7	15	5	20	1484.874
#181	ATF6	15	9	24	87.904
#182	ARNTL	15	13	28	1048.397
#183	CTCF	14	10	24	1066.867
#184	ZNF37A	14	12	26	1097.706
#185	TLX3	14	3	17	50.662
#186	YY1	14	16	30	2003.271
#187	FOXG1	14	16	30	2393.722
#188	HOXB5	14	17	31	1891.908
#189	ZNF397	14	17	31	672.381
#190	ZNF140	14	8	22	268.565
#191	IRF3	14	15	29	2389.129
#192	NFE2L3	14	16	30	1818.607
#193	KLF15	14	26	40	5337.552
#194	HOPX	14	16	30	3998.683
#195	FOXM1	14	10	24	596.276
#196	MTA1	14	12	26	1114.647
#197	PFDN1	14	13	27	520.739
#198	AR	14	17	31	1783.834
#199	LMX1A	13	5	18	675.168
#200	IRX4	13	6	19	444.105
#201	TRIM25	13	13	26	315.486
#202	NFX1	13	20	33	1586.545
#203	SIX4	13	3	16	213.65
#204	TCF4	13	15	28	732.516
#205	NFKB2	13	22	35	1360.651
#206	ZNF215	13	15	28	579.955
#207	ZNF639	13	17	30	584.617
#208	PPARA	13	14	27	1573.16
#209	AFF4	13	21	34	5052.842
#210	TWIST1	13	18	31	2257.244
#211	ZNF24	13	9	22	381.685
#212	MAF	13	9	22	1103.232
#213	HAND2	13	6	19	180.74
#214	PAX8	13	14	27	990.97
#215	MSX2	13	7	20	377.692
#216	CREB3L1	13	19	32	2854.46
#217	ZNF85	13	8	21	436.445
#218	NR5A2	13	5	18	186.428
#219	HOXD9	13	18	31	2843.016
#220	VSX1	13	10	23	672.909
#221	RHOXF2B	13	12	25	1130.382
#222	FOXA1	13	19	32	2323.362
#223	GTF2I	13	15	28	3177.552
#224	HIF3A	13	13	26	551.306
#225	ELF1	13	10	23	436.703
#226	ZNF131	13	17	30	937.617
#227	RNF4	13	13	26	1161.495
#228	FOXJ3	13	17	30	2729.611
#229	MEIS1	13	19	32	4307.162
#230	SOX7	13	14	27	251.085
#231	SOX6	12	14	26	3395.057
#232	ZFP36L1	12	18	30	1289.487
#233	MLX	12	19	31	1550.716
#234	SIN3A	12	13	25	5854.657
#235	SOX5	12	7	19	494.794
#236	ZSCAN4	12	17	29	2122.69
#237	FOXC1	12	16	28	1327.425
#238	ATF5	12	4	16	549.668
#239	NFATC4	12	9	21	773.411
#240	MTA3	12	12	24	346.059
#241	ZSCAN18	12	18	30	936.405
#242	IRX2	12	23	35	2021.358
#243	NFE2	12	20	32	1817.393
#244	CITED2	12	13	25	2524.704
#245	ESR1	12	18	30	1324.004
#246	TRIM28	12	18	30	1653.996
#247	KLF4	12	9	21	379.841
#248	ANKRD30A	12	17	29	1386.528
#249	POU2F2	12	14	26	572.051
#250	TBP	12	15	27	483.574
#251	FOXJ2	12	16	28	1934.544
#252	CBFB	11	17	28	1417.041
#253	NKX2-3	11	9	20	1837.751
#254	ZXDA	11	8	19	1076.073
#255	NEUROD1	11	17	28	215.388
#256	NR1D1	11	12	23	1537.168
#257	ZNF174	11	13	24	1479.667
#258	POU3F1	11	3	14	52.671
#259	ZNF445	11	16	27	1078.584
#260	SIX3	11	14	25	1548.396
#261	MYT1	11	14	25	1807.878
#262	RCOR1	11	18	29	1354.852
#263	ZNF81	11	11	22	129.626
#264	ALX1	11	18	29	1754.624
#265	PHTF1	11	19	30	2471.91
#266	ERF	11	18	29	758.342
#267	SATB2	11	19	30	574.433
#268	TRIM29	11	11	22	687.456
#269	RELB	11	8	19	107.377
#270	NFATC2	11	13	24	304.37
#271	RORA	11	13	24	265.551
#272	ZC3H8	11	11	22	471.571
#273	STRN3	11	15	26	449.363
#274	JUN	11	21	32	1304.614
#275	TCF19	11	11	22	1080.749
#276	ZFPM1	11	13	24	1578.117
#277	TEAD3	11	4	15	259.671
#278	TPRX1	11	9	20	520.426
#279	ZNF70	10	21	31	693.773
#280	KDM5B	10	20	30	3506.062
#281	ASCL1	10	20	30	1745.318
#282	ZIC1	10	7	17	1163.591
#283	TCF20	10	12	22	1085.985
#284	NR4A2	10	21	31	884.109
#285	HIC1	10	20	30	1003.656
#286	SUPT4H1	10	19	29	319.973
#287	SNAPC5	10	21	31	1351.808
#288	HOXC4	10	14	24	2602.41
#289	LMO4	10	26	36	4167.828
#290	PAX3	10	13	23	283.976
#291	VAX2	10	3	13	550.757
#292	SOX2	10	14	24	1175.204
#293	SPIB	10	16	26	3431.636
#294	TSC22D3	10	18	28	1250.182
#295	KLF6	10	15	25	1286.311
#296	ARNT2	10	12	22	1582.023
#297	SOLH	10	16	26	320.315
#298	MYCN	10	16	26	3980.957
#299	YEATS4	10	5	15	601.991
#300	MEIS3	10	17	27	538.545
#301	NFIB	10	20	30	1110.622
#302	TSC22D1	10	16	26	830.831
#303	VENTX	10	19	29	1206.738
#304	ZFPM2	10	10	20	2245.728
#305	ZNF167	10	17	27	3256.898
#306	NEUROD2	10	26	36	2111.471
#307	SREBF1	9	10	19	295.893
#308	TAF4	9	14	23	980.502
#309	FOXN3	9	4	13	175.33
#310	SCAND2	9	15	24	2171.404
#311	ZNF483	9	16	25	2329.62
#312	CEBPA	9	18	27	1526.853
#313	ZNF35	9	22	31	1336.498
#314	FOXR1	9	20	29	1911.596
#315	SOX4	9	17	26	2747.49
#316	EN1	9	22	31	2119.107
#317	ZNF75D	9	21	30	3198.416
#318	ATF7	9	14	23	577.248
#319	UBN1	9	12	21	599.868
#320	TAL1	9	14	23	375.392
#321	CTBP1	9	9	18	185.655
#322	GLI2	9	13	22	626.824
#323	RXRA	8	15	23	418.863
#324	HCFC1	8	18	26	872.276
#325	OLIG2	8	21	29	2027.364
#326	GATAD2A	8	20	28	2854.587
#327	NKX1-2	8	12	20	110.57
#328	TCF7L1	8	18	26	1241.478
#329	PAX5	8	15	23	272.12
#330	FOXD2	8	23	31	1346.582
#331	ERG	8	18	26	1202.777
#332	FOXK2	8	13	21	579.757
#333	BACH2	8	10	18	1061.728
#334	TBX3	8	23	31	4421.004
#335	RERE	8	14	22	215.618
#336	EGR4	8	14	22	2100.257
#337	MEF2D	8	4	12	68.733
#338	EN2	8	20	28	1991.276
#339	TP73	8	18	26	1331.27
#340	CREBZF	8	13	21	672.401
#341	ETS2	8	8	16	374.219
#342	TFAP2A	8	15	23	1235.006
#343	ESRRA	8	10	18	1047.512
#344	NRL	8	15	23	988.122
#345	EGR2	8	16	24	1096.528
#346	EHF	8	19	27	1152.812
#347	ZNF213	8	19	27	464.078
#348	PGR	8	19	27	892.168
#349	PHF5A	8	12	20	603.018
#350	NPAS2	8	13	21	444.295
#351	FOXP1	8	15	23	635.833
#352	STAT5B	8	21	29	645.607
#353	TP63	8	15	23	766.638
#354	IKZF1	8	23	31	1078.985
#355	SRF	8	7	15	107.385
#356	GTF2H3	8	15	23	141.787
#357	GRHL2	8	15	23	208.641
#358	POU5F2	8	13	21	952.45
#359	WNT5A	8	20	28	2158.323
#360	NFYA	7	22	29	1633.026
#361	HINFP	7	21	28	1513.44
#362	NCOR1	7	20	27	1546.514
#363	PTH	7	9	16	280.57
#364	HR	7	15	22	984.086
#365	NR2E3	7	17	24	1995.828
#366	LHX4	7	21	28	1413.668
#367	JDP2	7	16	23	1024.843
#368	TARDBP	7	13	20	1179.349
#369	CTNNB1	7	24	31	1051.794
#370	LEF1	7	19	26	1771.19
#371	CREBBP	7	17	24	485.766
#372	LMX1B	7	12	19	870.617
#373	ZNF45	7	21	28	1007.756
#374	TLX2	7	17	24	871.499
#375	TFAP2E	7	19	26	697.242
#376	STAT3	7	8	15	315.881
#377	ZNF207	7	12	19	1131.049
#378	TRERF1	7	9	16	733.391
#379	E2F6	7	9	16	673.302
#380	PROX1	7	26	33	488.59
#381	ATF4	7	28	35	3595.847
#382	HOXC8	7	20	27	954.257
#383	TEAD2	6	4	10	76.687
#384	RARA	6	22	28	2280.197
#385	HOXA9	6	15	21	568.93
#386	XBP1	6	20	26	523.3
#387	HOXD13	6	14	20	134.551
#388	EGR1	6	21	27	1472.578
#389	ELK1	6	22	28	1396.701
#390	FOSL1	6	22	28	5173.093
#391	TFAM	6	26	32	2630.219
#392	TCFL5	6	21	27	2099.845
#393	FOXO4	6	17	23	1111.556
#394	SOX12	6	14	20	957.68
#395	TSHZ3	6	17	23	711.204
#396	SIX1	6	17	23	186.214
#397	E4F1	6	21	27	1249.968
#398	RUNX1T1	6	11	17	875.576
#399	FBXW7	6	18	24	351.819
#400	ZKSCAN2	6	11	17	392.956
#401	BRD8	6	20	26	1336.841
#402	NFKB1	6	23	29	1888.958
#403	FOXI3	6	19	25	387.314
#404	ZSCAN12	6	17	23	277.106
#405	FOSB	6	17	23	530.67
#406	MNX1	6	14	20	1022.442
#407	C1orf85	6	17	23	557.373
#408	ZHX2	6	24	30	1246.681
#409	E2F8	6	18	24	949.888
#410	SP140	5	15	20	233.886
#411	ZNF175	5	21	26	851.052
#412	MYC	5	18	23	201.055
#413	HOXA10	5	17	22	343.582
#414	ZFHX2	5	14	19	1442.415
#415	ZSCAN10	5	17	22	1030.139
#416	TFCP2	5	19	24	359.081
#417	SMAD2	5	18	23	621.871
#418	ZRANB2	5	13	18	1528.736
#419	NR3C1	5	5	10	33.895
#420	NFE2L2	5	19	24	957.251
#421	REST	5	9	14	310.537
#422	FOXP3	5	17	22	163.599
#423	ZEB2	5	6	11	65.834
#424	IRX3	5	17	22	1014.602
#425	FOXO3	5	14	19	692.978
#426	MGA	5	15	20	518.922
#427	LHX9	5	9	14	546.602
#428	PBX1	5	21	26	924.297
#429	HNF1B	5	20	25	1216.673
#430	KLF16	5	12	17	506.21
#431	ST18	5	17	22	190.434
#432	TCF21	5	20	25	1500.329
#433	ZBTB38	4	18	22	493.219
#434	PRRX1	4	24	28	770.56
#435	LHX1	4	20	24	509.264
#436	BTG2	4	27	31	568.097
#437	CREB3L2	4	17	21	356.099
#438	DMRT2	4	14	18	1010.495
#439	PAX6	4	20	24	206.978
#440	SIM2	4	23	27	504.129
#441	RORC	4	20	24	577.399
#442	TFEC	4	22	26	501.348
#443	ZNF187	4	16	20	1094.976
#444	HDAC1	4	23	27	837.561
#445	HOXA7	4	11	15	795.401
#446	PITX1	4	15	19	165.038
#447	ZSCAN2	4	30	34	621.547
#448	SOX11	4	19	23	490.074
#449	MAX	4	19	23	896.253
#450	ZKSCAN1	4	19	23	572.892
#451	SIX6	4	19	23	799.836
#452	E2F1	4	8	12	297.41
#453	BCL3	4	20	24	1553.872
#454	LCOR	4	13	17	305.381
#455	ZNF256	4	14	18	370.227
#456	CREB3L4	4	17	21	2019.891
#457	LHX2	4	14	18	471.148
#458	IRX5	4	25	29	866.83
#459	DLX3	4	14	18	2425.869
#460	HCLS1	4	21	25	630.691
#461	ZBTB25	3	19	22	252.213
#462	NFATC3	3	19	22	200.499
#463	BARX1	3	23	26	1042.58
#464	RBPJL	3	17	20	452.844
#465	JUNB	3	11	14	332.548
#466	RHOXF2	3	18	21	317.597
#467	NFIA	3	9	12	355.425
#468	THRB	3	21	24	988.979
#469	SMAD3	3	23	26	1184.269
#470	ZIC5	3	17	20	155.863
#471	NFIL3	3	23	26	1331.446
#472	KLF7	3	19	22	237.348
#473	ETV3L	3	24	27	977.255
#474	MTF1	3	14	17	612.207
#475	HOXA11	3	19	22	554.515
#476	STAT5A	3	13	16	71.15
#477	MEIS3P1	3	15	18	949.668
#478	ELK3	3	26	29	732.899
#479	HMBOX1	3	16	19	235.77
#480	MLXIPL	2	12	14	82.783
#481	AEBP1	2	18	20	590.092
#482	GLIS3	2	25	27	404.01
#483	ZNF135	2	14	16	161.415
#484	ZNF134	2	23	25	314.562
#485	TSHZ2	2	21	23	1072.418
#486	ZNF202	2	21	23	926.416
#487	ATF6B	2	21	23	381.823
#488	POU5F1	2	21	23	695.46
#489	CITED1	2	8	10	54.217
#490	ZNF193	2	17	19	645.804
#491	ZNF33A	2	18	20	143.922
#492	STAT2	2	18	20	274.249
#493	ESRRB	2	25	27	817.11
#494	EVX1	2	22	24	262.335
#495	ONECUT2	2	22	24	230.649
#496	TBX6	1	31	32	179.364
#497	KLF3	1	25	26	68.027
#498	DLX1	1	19	20	92.898
#499	BLZF1	1	18	19	261.78
#500	BTAF1	0	24	24	0