Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GATAD2A	54	5	59	293.86
#2	AFF4	50	7	57	594.094
#3	SLC2A4RG	50	4	54	1188.401
#4	FOXC1	47	16	63	6023.389
#5	ZEB1	46	3	49	583.657
#6	YBX1	42	7	49	1762.713
#7	PHF5A	42	1	43	13.278
#8	PURA	39	12	51	2001.664
#9	FOXP4	39	6	45	168.907
#10	FOXO1	38	9	47	1075.531
#11	GATA3	37	11	48	1446.766
#12	NFIC	37	10	47	893.435
#13	FOXM1	37	8	45	1737.207
#14	NFAT5	37	5	42	585.926
#15	MMP14	37	12	49	1811.205
#16	ZFP36L1	36	12	48	738.734
#17	HOXA3	36	8	44	1072.608
#18	PRRX1	35	1	36	434.751
#19	IKZF1	34	1	35	15.211
#20	GAS7	33	4	37	310.055
#21	NFIL3	33	11	44	1702.234
#22	HOXA9	32	4	36	7833.193
#23	RUNX3	32	5	37	4015.377
#24	GTF2H4	32	5	37	517.798
#25	TRIM22	32	8	40	1159.041
#26	MYC	32	8	40	1260.13
#27	JDP2	31	9	40	414.659
#28	MSL3	31	8	39	332.597
#29	RUNX2	31	8	39	368.321
#30	ZFP36L2	31	15	46	1719.49
#31	ZNF643	31	12	43	1931.821
#32	TFEC	31	4	35	630.832
#33	TAF4	30	6	36	2499.298
#34	TCF7L1	30	20	50	1677.129
#35	SNAI2	30	3	33	423.33
#36	MEF2C	30	8	38	1638.03
#37	NOTCH1	30	10	40	1229.27
#38	RORA	29	6	35	501.008
#39	AATF	29	9	38	1066.658
#40	ELF4	29	15	44	2281.975
#41	ESR1	29	14	43	1811.479
#42	NFIX	29	24	53	1969.237
#43	ZEB2	28	6	34	607.243
#44	EBF1	28	5	33	260.335
#45	IRF8	28	2	30	703.872
#46	ENO1	28	11	39	1325.109
#47	FOXN2	28	9	37	485.311
#48	NR2C1	28	16	44	2033.776
#49	MLL	28	10	38	456.8
#50	PRDM1	28	12	40	1942.455
#51	ZNF187	27	0	27	0
#52	BCL11B	27	8	35	198.823
#53	KLF11	27	7	34	670.776
#54	FOXA1	27	10	37	2019.427
#55	ZNF500	27	7	34	335.331
#56	MEIS3P1	26	17	43	1667.75
#57	FLI1	26	6	32	430.265
#58	ZNF3	25	10	35	780.014
#59	ZNF496	25	9	34	667.914
#60	HSF1	25	8	33	860.141
#61	HDAC2	25	6	31	1237.085
#62	TFEB	25	15	40	547.209
#63	TCF4	25	6	31	242.256
#64	SIX5	25	11	36	826.488
#65	ZNF193	25	3	28	177.615
#66	CNOT8	25	16	41	2081.249
#67	SUPT6H	25	14	39	2360.268
#68	E2F7	25	9	34	882.947
#69	STAT1	24	7	31	5567.977
#70	IRF1	24	6	30	75.467
#71	TAF4B	24	11	35	1509.231
#72	RORC	24	19	43	1577.14
#73	FOXF2	24	5	29	89.331
#74	E2F3	24	13	37	1363.339
#75	GLIS2	24	8	32	460.58
#76	ZNF192	24	12	36	1342.153
#77	TWIST2	24	8	32	317.333
#78	NR2F6	24	16	40	1864.724
#79	ZNF134	24	15	39	2000.043
#80	NOLC1	23	13	36	2362.427
#81	AEBP1	23	6	29	445.091
#82	AR	23	12	35	3005.177
#83	RUNX1T1	23	9	32	421.154
#84	TSHZ2	23	10	33	717.743
#85	EOMES	23	4	27	46.64
#86	TWIST1	23	19	42	2341.695
#87	ZNF133	23	13	36	1202.295
#88	TFAP2A	23	16	39	1519.707
#89	BACH2	23	11	34	260.372
#90	BCL3	23	21	44	2766.948
#91	UHRF1	22	6	28	552.628
#92	TSHZ3	22	4	26	35.1
#93	SUPT4H1	22	16	38	1617.252
#94	IRX3	22	17	39	6499.517
#95	ZNF85	22	12	34	783.006
#96	GTF2IRD1	22	13	35	1297.057
#97	MECOM	22	17	39	1221.997
#98	SMAD9	22	13	35	477.461
#99	PTTG1	22	3	25	161.403
#100	ZFPM2	21	6	27	199.746
#101	HCLS1	21	2	23	10.526
#102	ZNF131	21	13	34	2000.972
#103	FOXQ1	21	13	34	1077.932
#104	KLF6	21	11	32	1738.29
#105	XBP1	21	11	32	1448.34
#106	NFE2L3	21	20	41	2340.239
#107	EGR1	21	13	34	742.04
#108	FOXJ3	21	14	35	1572.011
#109	BTG2	21	17	38	1401.024
#110	UBN1	21	13	34	1118.398
#111	E2F8	21	6	27	419.275
#112	ZSCAN16	21	7	28	460.573
#113	HMGB1	21	11	32	1243.78
#114	SOX4	21	15	36	1979.458
#115	NFYC	21	8	29	517.117
#116	TCF19	21	4	25	118.875
#117	HOXA7	21	9	30	2611.004
#118	TGIF2	21	19	40	2584.307
#119	ARNT	21	10	31	638.64
#120	ZNF236	21	17	38	1691.158
#121	BHLHE40	21	17	38	1292.779
#122	MEIS2	20	8	28	389.096
#123	PGBD1	20	16	36	743.534
#124	E2F5	20	10	30	1563.994
#125	SMAD4	20	17	37	1411.292
#126	TEAD1	20	13	33	1176.519
#127	CEBPB	20	11	31	794.163
#128	FOXN3	20	12	32	544.425
#129	KDM5B	20	12	32	1025.22
#130	E2F1	20	5	25	612.488
#131	MITF	20	14	34	932.288
#132	CREB5	20	14	34	505.301
#133	TRPS1	20	18	38	2325.277
#134	CREB3L4	20	18	38	1418.384
#135	GCFC1	20	16	36	833.611
#136	LASS2	20	18	38	1329.163
#137	GLI3	20	14	34	916.48
#138	ZNF396	20	18	38	2407.521
#139	SOLH	19	13	32	661.688
#140	ATF7	19	19	38	1391.917
#141	ZNF213	19	7	26	861.23
#142	TEAD2	19	15	34	1029.996
#143	CREBL2	19	14	33	1884.622
#144	MEOX2	19	11	30	1086.772
#145	CEBPA	19	9	28	184.555
#146	HOXA2	19	8	27	586.78
#147	ATF3	19	16	35	1301.143
#148	ZXDA	19	11	30	903.075
#149	ZNF367	19	4	23	161.485
#150	BHLHE41	19	12	31	396.773
#151	LZTS1	19	7	26	658.402
#152	ZNF202	19	13	32	782.255
#153	TADA2A	18	12	30	1201.925
#154	TSHZ1	18	15	33	2170.417
#155	ADNP2	18	11	29	1056.614
#156	STAT3	18	18	36	1315.78
#157	LMO4	18	18	36	1354.163
#158	AHCTF1	18	14	32	770.212
#159	SCAND1	18	11	29	1022.77
#160	FOS	18	13	31	743.474
#161	RERE	18	14	32	1753.437
#162	ZNF117	18	20	38	2352.707
#163	SCMH1	18	9	27	524.632
#164	NFIA	18	14	32	499.941
#165	ELK1	18	15	33	2377.25
#166	SPDEF	18	9	27	507.941
#167	TFCP2	18	15	33	1862.023
#168	KLF5	18	19	37	1764.673
#169	HDAC1	17	16	33	923.046
#170	ALS2CR8	17	21	38	1151.174
#171	HEY2	17	19	36	1816.887
#172	NR2F2	17	16	33	1678.224
#173	TP63	17	12	29	1121.702
#174	PBX3	17	21	38	2860.541
#175	HOXC9	17	11	28	725.912
#176	MEOX1	17	10	27	614.13
#177	ZSCAN29	17	12	29	1407.23
#178	HOXC4	17	10	27	552.261
#179	PLSCR1	17	5	22	1055.713
#180	LASS6	17	18	35	1340.831
#181	PURB	17	15	32	693.934
#182	ZNF91	17	21	38	1838.562
#183	ETS1	17	10	27	679.19
#184	TSC22D3	17	10	27	676.333
#185	FBXW7	17	11	28	369.895
#186	ECSIT	17	17	34	918.077
#187	OVOL1	17	18	35	2410.218
#188	DBP	17	16	33	973.959
#189	KLF3	17	14	31	993.455
#190	PBX2	17	11	28	842.155
#191	YEATS4	17	17	34	2689.054
#192	CBFB	17	15	32	1741.911
#193	ZHX2	17	19	36	1744.663
#194	RXRA	17	19	36	1413.029
#195	ZKSCAN4	17	4	21	98.791
#196	KLF10	17	15	32	618.052
#197	HMG20B	16	24	40	1312.603
#198	EGR2	16	11	27	874.236
#199	STAT2	16	8	24	130.621
#200	ZNF263	16	6	22	856.383
#201	HOPX	16	21	37	1652.467
#202	TCF20	16	14	30	357.774
#203	RUNX1	16	14	30	550.525
#204	ZKSCAN1	16	15	31	1300.832
#205	C5orf41	16	16	32	855.615
#206	PPARD	16	19	35	1411.283
#207	GATAD2B	16	16	32	1511.837
#208	IRX5	16	11	27	571.748
#209	CSDA	16	22	38	954.693
#210	KLF12	16	14	30	1387.044
#211	MAFG	16	15	31	872.643
#212	MSRB2	16	18	34	612.178
#213	ZNF281	16	18	34	1713.281
#214	TFDP1	16	17	33	1099.502
#215	ZNF165	16	18	34	1127.072
#216	MEIS1	16	12	28	384.37
#217	NR1H3	15	7	22	183.965
#218	NFE2L1	15	21	36	1446.753
#219	SOX6	15	12	27	544.013
#220	ZRANB2	15	16	31	2242.783
#221	FOXO6	15	14	29	738.677
#222	E4F1	15	8	23	679.517
#223	ETV1	15	13	28	2073.249
#224	TCFL5	15	19	34	1823.794
#225	FOSL2	15	21	36	1217.964
#226	KLF4	15	23	38	1540.234
#227	ZNF24	15	13	28	891.388
#228	SALL2	15	24	39	1155.385
#229	ZFHX4	15	11	26	904.004
#230	ZC3H8	15	11	26	792.876
#231	TAF5	15	13	28	757.127
#232	DDIT3	15	15	30	1908.159
#233	PCGF2	15	19	34	1586.218
#234	LEF1	15	19	34	2403.421
#235	NPAT	15	11	26	429.664
#236	HMBOX1	15	21	36	1387.351
#237	SP1	14	15	29	1142.964
#238	VAV1	14	9	23	603.77
#239	DRAP1	14	10	24	669.14
#240	SOX12	14	21	35	1286.48
#241	MTA1	14	20	34	892.141
#242	TFAM	14	16	30	822.447
#243	ERG	14	13	27	413.892
#244	ZNF207	14	25	39	1181.364
#245	HMGA1	14	19	33	1339.713
#246	ZNF238	14	22	36	1073.732
#247	TAF12	14	14	28	686.634
#248	FOXP1	14	18	32	1200.519
#249	ZNF18	14	13	27	969.848
#250	GATA6	13	21	34	710.943
#251	TBX3	13	26	39	2968.537
#252	SLC30A9	13	19	32	1268.424
#253	HMGB2	13	9	22	313.715
#254	AHR	13	19	32	1445.567
#255	JUNB	13	8	21	871.703
#256	TGIF1	13	23	36	1904.995
#257	IRF9	13	11	24	1053.383
#258	ZNF169	13	17	30	2053.441
#259	UBP1	13	17	30	952.695
#260	ZSCAN2	13	12	25	725.024
#261	TRIM25	13	18	31	1126.316
#262	ETV6	13	11	24	389.656
#263	VDR	13	14	27	440.918
#264	FOXC2	13	14	27	479.977
#265	EPAS1	13	19	32	1023.47
#266	LCOR	13	21	34	1721.046
#267	TCEAL1	13	18	31	1156.23
#268	CUX1	13	23	36	1170.785
#269	SIX4	13	13	26	979.443
#270	MNT	13	17	30	567.603
#271	SMAD6	13	17	30	1012.93
#272	ZKSCAN3	13	7	20	411.913
#273	ZNF83	13	19	32	1999.596
#274	GTF2I	13	12	25	1194.447
#275	NR2F1	13	20	33	4115.895
#276	CREB3L2	13	21	34	1182.315
#277	ETV3	13	20	33	1889.069
#278	LHX6	13	21	34	1284.546
#279	ZNF268	12	14	26	348.021
#280	HDX	12	19	31	1343.289
#281	BACH1	12	12	24	2610.029
#282	MZF1	12	18	30	735.281
#283	HOXB9	12	17	29	739.885
#284	TSC22D1	12	10	22	1620.625
#285	PA2G4	12	15	27	788.304
#286	ATF6B	12	17	29	323.968
#287	CTNNB1	12	17	29	903.495
#288	ZHX1	12	22	34	1394.667
#289	HOXD10	12	17	29	1118.563
#290	TCF3	12	21	33	748.123
#291	TAF1B	12	19	31	708.914
#292	RARA	12	15	27	861.769
#293	ZNF45	12	19	31	1282.658
#294	PFDN1	12	17	29	714.468
#295	MBD1	12	13	25	785.788
#296	SATB1	12	26	38	2435.226
#297	ZNF639	12	22	34	2288.975
#298	SPEN	12	20	32	1044.726
#299	ZFHX3	12	20	32	1312.123
#300	BLZF1	12	12	24	756.869
#301	CNOT7	12	18	30	1267.305
#302	ZNF256	12	13	25	506.751
#303	ZNF397	12	21	33	1430.385
#304	CDKN2A	11	17	28	997.36
#305	ZNF438	11	16	27	819.616
#306	NFATC1	11	15	26	1283.048
#307	C1orf85	11	10	21	414.161
#308	TULP4	11	19	30	2256.161
#309	BCL6	11	18	29	1357.126
#310	ARNT2	11	28	39	1886.668
#311	TCF7L2	11	20	31	453.884
#312	IRF6	11	19	30	1640.902
#313	ZNF75D	11	20	31	1129.326
#314	TCF7	11	10	21	163.237
#315	POU6F1	11	19	30	1117.896
#316	SMAD2	11	17	28	1041.336
#317	HEYL	11	10	21	235.933
#318	ZSCAN5A	11	21	32	1144.695
#319	ELF1	11	17	28	503.727
#320	PKNOX1	11	16	27	468.727
#321	TEAD3	11	14	25	392.187
#322	HOXC10	11	15	26	1543.861
#323	SP3	11	14	25	1095.48
#324	KLF9	11	17	28	639.674
#325	REL	10	24	34	1651.747
#326	THRB	10	27	37	1264.2
#327	ETV5	10	12	22	706.367
#328	ZNF197	10	16	26	530.959
#329	RCAN1	10	20	30	626.036
#330	HES1	10	16	26	612.048
#331	TEAD4	10	12	22	438.333
#332	JUN	10	15	25	782.205
#333	HIF1A	10	15	25	681.937
#334	SREBF2	10	18	28	605.649
#335	CSRNP2	10	16	26	904.787
#336	MLX	10	11	21	280.701
#337	CREB3	10	18	28	604.854
#338	IRX1	10	18	28	656.82
#339	FOXO4	10	14	24	965.841
#340	CSRNP3	10	21	31	955.37
#341	MAFB	10	14	24	413.492
#342	HOXB7	10	15	25	752.354
#343	FUBP1	10	24	34	907.83
#344	STAT5B	10	24	34	898.571
#345	ZSCAN12	10	11	21	536.2
#346	ZNF277	10	24	34	1303.227
#347	DLX4	10	20	30	784.774
#348	ATF5	10	19	29	6043.22
#349	ZFP37	10	24	34	819.18
#350	YY1	10	16	26	783.912
#351	TRERF1	10	25	35	1083.155
#352	TSC22D4	10	19	29	776.883
#353	NFYB	10	14	24	732.011
#354	RFX3	9	17	26	910.752
#355	EHF	9	31	40	1142.627
#356	SOX9	9	20	29	796.676
#357	MTF1	9	11	20	265.749
#358	SOX17	9	12	21	343.312
#359	GRHL2	9	22	31	1708.701
#360	MAFF	9	22	31	703.149
#361	NFKB2	9	20	29	768.913
#362	ZNF92	9	22	31	1290.239
#363	IRF7	9	11	20	263.161
#364	ZSCAN18	9	19	28	1247.419
#365	ZNF19	9	15	24	393.217
#366	ZNF167	9	22	31	838.442
#367	TAF7	9	17	26	807.758
#368	SMAD3	9	23	32	804.434
#369	ZNF217	9	19	28	745.998
#370	MSX1	9	24	33	425.023
#371	SNAPC2	9	20	29	758.031
#372	GATAD1	9	14	23	418.728
#373	PPARA	9	21	30	665
#374	FOXK2	9	18	27	1183.576
#375	KLF2	9	22	31	281.599
#376	RFX5	9	16	25	798.923
#377	ZNF70	9	14	23	1008.319
#378	TP53	9	21	30	727.946
#379	TFAP2C	9	17	26	657.74
#380	ZGPAT	9	13	22	289.068
#381	ETV7	9	9	18	5990.117
#382	HHEX	9	27	36	779.34
#383	ZNF434	9	14	23	1806.649
#384	SREBF1	8	22	30	536.668
#385	NFYA	8	13	21	598.373
#386	TFDP2	8	27	35	1496.734
#387	RFXANK	8	16	24	538.783
#388	HOMEZ	8	17	25	934.32
#389	GABPB1	8	12	20	660.089
#390	ZNF232	8	18	26	1050.595
#391	PHTF1	8	20	28	1088.647
#392	CREM	8	16	24	720.817
#393	MEF2A	8	18	26	300.749
#394	TAL1	8	14	22	528.36
#395	MLLT10	8	24	32	1566.287
#396	NFATC4	8	25	33	817.869
#397	MSX2	8	31	39	1545.394
#398	SIN3A	8	19	27	1414.178
#399	ELK4	8	18	26	1217.07
#400	STAT6	8	19	27	1044.275
#401	PPARG	8	20	28	561.639
#402	HOXB5	8	11	19	481.569
#403	HEY1	8	21	29	1188.379
#404	ERF	8	17	25	1207.165
#405	FOXK1	8	12	20	441.897
#406	MAX	8	16	24	706.165
#407	KLF7	8	17	25	610.414
#408	NFATC3	8	11	19	498.159
#409	TAF5L	8	20	28	962.242
#410	SOX13	7	18	25	580.53
#411	HOXB6	7	13	20	546.914
#412	NR4A2	7	26	33	871.018
#413	HOXB3	7	11	18	563.755
#414	NKX3-1	7	32	39	1009.048
#415	NPAS2	7	27	34	1107.929
#416	PBX1	7	22	29	1093.996
#417	CITED2	7	17	24	700.958
#418	NANOGNB	7	15	22	396.755
#419	FOXO3	7	19	26	812.022
#420	MAF	7	19	26	783.742
#421	ZNF37A	7	15	22	569.229
#422	NFE2L2	7	18	25	1204.17
#423	HSF2	7	13	20	222.905
#424	CBFA2T2	7	18	25	352.858
#425	ZHX3	7	16	23	711.614
#426	CSRNP1	7	12	19	438.282
#427	TCF25	7	19	26	507.89
#428	SMAD1	7	18	25	746.23
#429	SMAD5	7	16	23	452.376
#430	NFXL1	7	13	20	397.642
#431	CBL	7	12	19	351.055
#432	ZBTB48	7	12	19	348.597
#433	ZNF148	7	15	22	473.625
#434	KDM5A	7	15	22	484.387
#435	RELA	7	14	21	383.592
#436	CEBPD	6	23	29	634.189
#437	ZXDC	6	17	23	440.033
#438	NR3C1	6	23	29	446.566
#439	NFIB	6	25	31	774.634
#440	ZFP90	6	17	23	489.894
#441	NR1D2	6	13	19	265.118
#442	TCF12	6	22	28	1016.839
#443	NR3C2	6	24	30	599.556
#444	ZNF41	6	14	20	353.212
#445	ZNF138	6	20	26	296.567
#446	TP73	6	12	18	539.181
#447	ZNF323	6	25	31	631.714
#448	HOXB2	6	15	21	463.703
#449	JUND	6	20	26	595.793
#450	SOX18	6	19	25	535.687
#451	PLAGL2	6	21	27	419.04
#452	ZNF274	6	20	26	381.513
#453	SP4	6	15	21	272.977
#454	MYCL1	6	18	24	402.703
#455	SOX7	6	23	29	725.001
#456	TARDBP	6	15	21	384.97
#457	SRF	6	19	25	761.354
#458	ATF6	6	18	24	624.399
#459	NCOR1	5	23	28	402.561
#460	SCML1	5	25	30	847.393
#461	RBCK1	5	27	32	770.366
#462	TEF	5	13	18	315.842
#463	PRDM2	5	20	25	428.456
#464	PKNOX2	5	15	20	228.228
#465	ELF2	5	19	24	710.543
#466	IRF5	5	20	25	1281.057
#467	GATA2	5	27	32	921.292
#468	SATB2	5	27	32	1117.325
#469	WNT5A	5	17	22	191.441
#470	ZBTB25	5	19	24	452.447
#471	NFX1	5	16	21	477.165
#472	ZBTB38	5	19	24	337.962
#473	ZNF33B	4	24	28	416.451
#474	EGR3	4	21	25	443.05
#475	MGA	4	20	24	446.367
#476	CTBP1	4	18	22	341.986
#477	CREBZF	4	21	25	581.139
#478	FOXS1	4	13	17	217.364
#479	ARNTL	4	19	23	624.867
#480	ZNF174	4	18	22	281.777
#481	SIX1	4	30	34	823.518
#482	ZNF175	4	24	28	1005.524
#483	ARID3A	4	18	22	363.339
#484	MXD1	3	23	26	327.978
#485	ZNF93	3	19	22	1045.925
#486	RFXAP	3	15	18	504.233
#487	RB1	3	15	18	190.79
#488	ETS2	3	24	27	440.008
#489	POU2F1	3	24	27	201.427
#490	ELF3	3	27	30	344.491
#491	ZNF140	3	17	20	237.336
#492	HOXD8	3	22	25	288.122
#493	MESP2	2	22	24	270.786
#494	GTF2H2	2	24	26	297.862
#495	PGR	2	39	41	448.501
#496	CBFA2T3	2	32	34	339.332
#497	C2orf3	2	21	23	577.294
#498	ZNF33A	2	16	18	87.394
#499	PEG3	1	30	31	89.665
#500	CCRN4L	1	22	23	123.285