Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF236	80	1	81	53.914
#2	FOSL1	45	2	47	1480.837
#3	PAX8	40	6	46	339.394
#4	ATF1	39	5	44	609.111
#5	REST	39	5	44	1478.38
#6	USF2	38	7	45	13735.489
#7	TBX5	38	7	45	1419.87
#8	TARDBP	38	9	47	1083.341
#9	FOXF1	36	5	41	776.809
#10	TFAP4	35	7	42	4349.843
#11	EVX1	34	8	42	3261.939
#12	NR2F6	34	9	43	2575.685
#13	ZKSCAN3	34	1	35	487.285
#14	CBL	34	12	46	3521.605
#15	TCF7L1	32	4	36	4166.055
#16	FOXA1	32	2	34	615.63
#17	TBX2	31	4	35	2953.254
#18	NR4A3	31	10	41	16559.073
#19	PHOX2B	30	8	38	2726.619
#20	SALL2	29	3	32	32.912
#21	ELK1	29	6	35	2956.837
#22	XBP1	29	2	31	2330.515
#23	E4F1	28	7	35	1942.812
#24	PPARD	28	3	31	2416.723
#25	TFEB	28	7	35	2167.037
#26	MTF1	28	7	35	934.884
#27	PKNOX2	28	4	32	287.141
#28	TAF4B	27	7	34	251.991
#29	STRN3	27	8	35	3674.616
#30	HOXA11	26	7	33	1188.985
#31	POU2F1	26	6	32	5381.436
#32	LHX3	25	1	26	101.633
#33	HCLS1	25	3	28	454.06
#34	AR	25	5	30	10268.94
#35	NPAT	25	3	28	31.456
#36	ADNP	24	8	32	1989.964
#37	HMG20B	24	11	35	2490.592
#38	ESR1	23	6	29	238.999
#39	ZNF24	23	13	36	1932.649
#40	SNAPC4	23	4	27	66.652
#41	GATA3	23	8	31	751.659
#42	E2F3	23	8	31	3914.163
#43	MYF6	23	6	29	703.608
#44	POU4F2	23	11	34	1665.788
#45	SRY	22	7	29	993.393
#46	CREB1	22	4	26	354.097
#47	HOXB9	22	8	30	11781.275
#48	ZNF187	22	2	24	1046.078
#49	KLF6	22	3	25	734.014
#50	SLC30A9	22	9	31	2116.571
#51	NFE2L2	21	12	33	4922.359
#52	TBX19	21	6	27	6270.422
#53	CTCF	21	8	29	347.217
#54	ZNF444	21	10	31	442.042
#55	HMGA2	21	9	30	486.251
#56	PHTF1	21	8	29	1208.512
#57	ELF2	20	9	29	296.841
#58	SOX12	20	11	31	2147.194
#59	HOXC11	20	3	23	170.117
#60	SOX10	20	5	25	620.392
#61	NFATC1	20	9	29	2999.013
#62	JUNB	20	9	29	1005.233
#63	ZEB1	20	2	22	599.625
#64	SPDEF	19	9	28	3181.553
#65	TCF4	19	4	23	1401.603
#66	ZNF165	19	15	34	2241.168
#67	LASS6	19	8	27	1096.245
#68	NR1I3	19	4	23	109.577
#69	SOX2	19	3	22	172.668
#70	IRF2	19	6	25	1444.548
#71	FOXC1	19	5	24	1910.517
#72	RUNX1T1	19	6	25	1048.511
#73	NPAS2	18	4	22	173.197
#74	IRF8	17	7	24	1129.37
#75	NR3C1	17	7	24	1512.428
#76	POU5F1B	17	5	22	6145.08
#77	YY1	17	7	24	626.317
#78	ZKSCAN1	17	12	29	669.996
#79	NPAS1	17	1	18	57.594
#80	HDAC2	17	10	27	1523.716
#81	EMX1	17	7	24	1027.754
#82	EN1	16	9	25	381.5
#83	HIC1	16	4	20	1029.56
#84	STAT5B	16	12	28	9473.116
#85	GAS7	16	8	24	3343.436
#86	CREBL2	16	9	25	2843.453
#87	TCF7L2	16	10	26	1491.011
#88	TCF15	16	2	18	106.747
#89	HIF3A	16	8	24	9689.502
#90	FOXN1	16	4	20	246.416
#91	ELK3	16	5	21	4718.091
#92	ETV1	16	7	23	1082.882
#93	VAV1	16	6	22	1713.372
#94	TCF12	15	11	26	2121.516
#95	HCFC1	15	6	21	323.021
#96	FOXO4	15	3	18	4124.328
#97	FOXN3	15	8	23	1466.741
#98	MLXIPL	15	7	22	1237.022
#99	DLX2	15	6	21	30251.403
#100	MAF	15	5	20	1059.734
#101	NFIL3	15	9	24	3465.855
#102	FOXA2	15	9	24	816.816
#103	BACH1	15	5	20	820.869
#104	ZBTB25	15	12	27	826.563
#105	GSC2	15	4	19	125.109
#106	PDX1	14	8	22	593.337
#107	ELF1	14	10	24	1903.747
#108	KDM5B	14	11	25	5705.82
#109	FUBP1	14	9	23	2902.137
#110	TCF3	14	9	23	737.126
#111	TCEAL1	14	13	27	3347.622
#112	ZSCAN5A	14	10	24	242.729
#113	PAX3	14	8	22	3082.06
#114	AHCTF1	14	11	25	8881.733
#115	SOX15	14	8	22	3110.122
#116	TFE3	14	6	20	161.131
#117	MTA1	14	10	24	477.587
#118	SOX13	14	5	19	61.533
#119	SREBF1	14	14	28	8233.022
#120	MLL	14	3	17	118.018
#121	MEF2C	14	6	20	1632.787
#122	MAFF	13	8	21	713.676
#123	FLI1	13	12	25	6289.672
#124	NFE2	13	6	19	554.711
#125	SP4	13	7	20	116.117
#126	MYCL1	13	11	24	596.119
#127	ETS2	13	14	27	4668.759
#128	HIF1A	13	15	28	5088.503
#129	TRIM29	13	10	23	1166.663
#130	MEIS3P1	13	16	29	2347.349
#131	CREBZF	13	6	19	1428.179
#132	ZEB2	13	8	21	1811.477
#133	PBX1	13	10	23	682.135
#134	ZNF83	13	7	20	159.133
#135	ZNF207	12	11	23	1462.57
#136	TFCP2L1	12	13	25	9076.382
#137	GTF2H3	12	9	21	14721.578
#138	TAL1	12	7	19	1724.071
#139	RARB	12	5	17	305.74
#140	NFYA	12	7	19	203.662
#141	CEBPA	12	14	26	5970.81
#142	SOX1	12	7	19	4401.164
#143	ELK4	12	6	18	187.181
#144	ATF2	12	12	24	312.875
#145	RFX5	12	8	20	322.261
#146	PBX2	12	9	21	2206.668
#147	TFAM	12	10	22	2573.782
#148	CLOCK	12	6	18	152.721
#149	MYF5	12	5	17	122.218
#150	POU2F2	12	6	18	1301.326
#151	TCF25	11	13	24	5508.272
#152	SOX9	11	14	25	3429.829
#153	CEBPB	11	7	18	1397.069
#154	ZFP36L1	11	10	21	1380.132
#155	EDF1	11	12	23	422.392
#156	RCOR1	11	12	23	628.375
#157	NFIC	11	16	27	5669.428
#158	MSX1	11	9	20	3223.659
#159	CREM	11	10	21	1684.001
#160	NR5A2	11	9	20	511.07
#161	THRB	11	8	19	5272.004
#162	ARID3A	11	7	18	1126.709
#163	MTA2	11	6	17	737.295
#164	PAX5	11	9	20	1309.334
#165	RXRB	11	10	21	1389.349
#166	HOXA5	10	10	20	8592.472
#167	DBP	10	3	13	253.378
#168	PTTG1	10	11	21	5185.557
#169	ZNF238	10	11	21	2561.62
#170	CREB3L1	10	6	16	256.503
#171	ZNF157	10	8	18	256.698
#172	LMO4	10	11	21	974.671
#173	FOXM1	10	10	20	1923.448
#174	ZNF500	10	8	18	950.326
#175	SP3	10	7	17	966.474
#176	MZF1	10	9	19	2923.238
#177	RARG	10	10	20	1433.292
#178	ZSCAN12	10	11	21	5638.225
#179	TLX3	10	9	19	1315.066
#180	NFAT5	10	5	15	1267.561
#181	CNOT8	10	8	18	1309.409
#182	PRRX1	10	7	17	1054.373
#183	SMAD2	10	6	16	83.959
#184	IKZF4	10	10	20	255.172
#185	NOLC1	10	11	21	3753.699
#186	HNF1B	10	10	20	592.127
#187	RUNX3	10	7	17	2133.192
#188	PA2G4	10	9	19	395.821
#189	AFF1	10	13	23	2312.193
#190	BRD8	10	9	19	530.156
#191	E2F4	10	7	17	866.581
#192	FOXN2	10	7	17	87.238
#193	LHX6	10	9	19	3031.065
#194	AEBP1	10	8	18	761.006
#195	CBFA2T3	10	8	18	1031.763
#196	SOX4	10	13	23	2229.81
#197	HOXA1	9	11	20	2704.842
#198	NFIB	9	12	21	2266.03
#199	E2F2	9	8	17	6616.438
#200	TGIF1	9	12	21	1698.497
#201	BHLHE40	9	10	19	4061.588
#202	TRIM22	9	8	17	308.432
#203	ZNF91	9	14	23	3836.321
#204	HLF	9	6	15	3561.407
#205	TP63	9	9	18	5460.339
#206	GATA6	9	15	24	2510.925
#207	EPAS1	9	9	18	650.133
#208	PFDN1	9	10	19	222.642
#209	SATB1	9	11	20	3788.782
#210	POU3F4	9	8	17	9099.497
#211	ZNF93	9	8	17	1325.002
#212	CCRN4L	9	7	16	729.111
#213	SOX21	9	1	10	8.949
#214	FOXD1	9	13	22	1284.182
#215	TCF7	9	11	20	3346.33
#216	ELF5	9	7	16	636.514
#217	TBX3	9	12	21	1562.106
#218	TCFL5	8	12	20	341.145
#219	NCOR1	8	10	18	712.154
#220	MAX	8	9	17	771.862
#221	MMP14	8	7	15	308.72
#222	MAFB	8	11	19	2280.103
#223	TBX1	8	10	18	1267.591
#224	IKZF1	8	15	23	2564.559
#225	FOXD2	8	6	14	7030.086
#226	SOX5	8	10	18	171.09
#227	MYT1L	8	6	14	117.84
#228	FOXL1	8	12	20	1399.281
#229	BACH2	8	9	17	4935.52
#230	KLF3	8	6	14	2372.155
#231	TADA2A	8	11	19	425.812
#232	UBP1	8	14	22	532.851
#233	HOXB3	8	5	13	191.391
#234	ATF6	8	8	16	233.264
#235	ELF3	8	13	21	1595.347
#236	ZNF277	8	12	20	898.411
#237	CREB3L2	8	13	21	1452.57
#238	LZTS1	8	7	15	1981.115
#239	POU3F2	8	8	16	518.646
#240	FOXD3	8	12	20	2238.621
#241	HOXD1	8	12	20	770.741
#242	KLF10	8	11	19	836.91
#243	ZFP36L2	8	14	22	1406.076
#244	HAND2	8	8	16	2106.575
#245	NR2F2	7	12	19	716.844
#246	NFYB	7	10	17	374.008
#247	ELF4	7	13	20	3565.231
#248	HMGB2	7	6	13	1657.921
#249	TSC22D2	7	14	21	583.76
#250	MEOX1	7	7	14	631.994
#251	DRAP1	7	9	16	185.921
#252	HOXD3	7	7	14	230.569
#253	MSL3	7	13	20	5888.147
#254	AHR	7	8	15	371.863
#255	SRF	7	12	19	999.45
#256	SPIB	7	11	18	2123.271
#257	GTF2IRD1	7	13	20	567.743
#258	MSRB2	7	12	19	1343.654
#259	VAX2	7	5	12	1146.848
#260	SP140	7	8	15	1346.677
#261	HES1	7	7	14	329.291
#262	MEF2D	7	9	16	2029.971
#263	SPI1	7	19	26	2214.197
#264	NR5A1	7	12	19	21081.14
#265	RB1	7	12	19	392.338
#266	NKX2-1	7	6	13	134.889
#267	RBPJ	7	8	15	1310.549
#268	ZNF45	7	8	15	1625.015
#269	HNF4A	7	5	12	763.848
#270	HHEX	7	16	23	2583.973
#271	TULP4	7	10	17	584.308
#272	PGR	7	12	19	1441.746
#273	MXD1	7	11	18	718.786
#274	GLI3	7	6	13	156.632
#275	MEOX2	7	8	15	466.877
#276	TFEC	7	13	20	2636.436
#277	FOS	6	12	18	13090.404
#278	ZNF281	6	6	12	167.156
#279	FOSB	6	13	19	16620.187
#280	HDAC1	6	6	12	77.074
#281	HMX1	6	6	12	719.502
#282	BTG2	6	9	15	1495.271
#283	ZNF217	6	10	16	236.343
#284	THRA	6	9	15	744.16
#285	TFAP2C	6	12	18	2690.635
#286	ARNT2	6	14	20	582.603
#287	TFAP2B	6	12	18	1277.555
#288	ZIC1	6	13	19	2199.069
#289	HOXD12	6	8	14	2691.991
#290	STAT1	6	7	13	1158.883
#291	KLF2	6	13	19	1782.754
#292	FOXL2	6	13	19	708.566
#293	NFKB2	6	10	16	328.695
#294	TFDP1	6	12	18	3258.198
#295	RCAN1	6	10	16	744.411
#296	NR1H4	6	6	12	1335.087
#297	HOXB6	6	6	12	1486.26
#298	HOXB2	5	9	14	1113.135
#299	SLC2A4RG	5	11	16	478.107
#300	HOXA9	5	9	14	5530.266
#301	HOXA10	5	9	14	4244.039
#302	GBX2	5	8	13	355.442
#303	ZNF287	5	13	18	633.361
#304	MEF2A	5	13	18	1849.461
#305	ZNF189	5	12	17	1037.371
#306	ST18	5	7	12	470.968
#307	CITED2	5	12	17	421.997
#308	NR3C2	5	12	17	9870.57
#309	NR4A2	5	12	17	2408.261
#310	MYC	5	13	18	1086.163
#311	TCF20	5	11	16	950.2
#312	ENO1	5	14	19	2192.525
#313	ZNF131	5	11	16	4095.177
#314	STAT6	5	8	13	317.446
#315	ADNP2	5	11	16	201.279
#316	TSC22D3	5	9	14	137.913
#317	CBFB	5	9	14	5891.863
#318	HOXC13	5	18	23	705.561
#319	NKX2-8	5	7	12	192.863
#320	IRF1	5	11	16	994.871
#321	MNX1	5	7	12	5396.985
#322	ZFPM2	5	6	11	215.463
#323	LASS2	5	12	17	872.715
#324	NOTCH1	5	5	10	1442.371
#325	NR1H3	5	8	13	2808.974
#326	ZNF155	5	10	15	450.5
#327	PITX1	5	12	17	1203.899
#328	TEAD4	5	11	16	718.731
#329	FOXJ3	5	16	21	551.02
#330	CIR1	5	13	18	5913.131
#331	BUD31	5	9	14	1981.794
#332	E2F5	5	10	15	2186.127
#333	ZNF140	5	10	15	491.539
#334	BCL11B	5	10	15	4923.105
#335	TAF4	5	13	18	1546.407
#336	SMAD5	5	11	16	741.689
#337	SOX11	5	19	24	5038.561
#338	JUND	5	15	20	1338.836
#339	NR2E3	5	9	14	191.889
#340	SIX1	5	10	15	796.101
#341	TGIF2	5	7	12	343.001
#342	TAF13	5	11	16	656.17
#343	HOPX	4	11	15	638.518
#344	HEY2	4	9	13	1235.821
#345	ZNF175	4	5	9	638.708
#346	IRX5	4	13	17	602.63
#347	PLAG1	4	9	13	464.417
#348	FOXO1	4	8	12	4610.264
#349	TSC22D1	4	17	21	1009.979
#350	BTAF1	4	8	12	177.967
#351	EGR1	4	12	16	5223.432
#352	CTNNB1	4	10	14	2830.143
#353	GRHL2	4	9	13	584.733
#354	CDKN2A	4	13	17	1628.918
#355	NRL	4	7	11	693.939
#356	RERE	4	15	19	1269.982
#357	TRPS1	4	15	19	1651.453
#358	FOXF2	4	9	13	407.22
#359	KLF5	4	15	19	1087.847
#360	IRF9	4	12	16	1042.149
#361	ARNT	4	14	18	120.14
#362	PKNOX1	4	8	12	103.391
#363	LEF1	4	12	16	1433.705
#364	ZNF394	4	11	15	1855.915
#365	STAT3	4	11	15	718.38
#366	TAF1B	4	7	11	116.03
#367	HSF1	4	12	16	1695.125
#368	CSDA	4	15	19	1626.433
#369	YBX1	4	14	18	1183.469
#370	ZSCAN18	4	11	15	1614.652
#371	KLF9	4	15	19	938.498
#372	JUN	4	13	17	1757.95
#373	RXRG	4	9	13	302.465
#374	SIX2	4	12	16	3553.27
#375	ZNF41	4	10	14	346.872
#376	RBCK1	3	15	18	1753.137
#377	ZNF268	3	7	10	94.498
#378	KLF12	3	12	15	501.546
#379	SLC26A3	3	12	15	2950.24
#380	PAX4	3	10	13	619.354
#381	SCAND1	3	11	14	142.389
#382	NFE2L1	3	6	9	617.969
#383	KLF4	3	15	18	3043.618
#384	SIM1	3	14	17	2717.502
#385	BCL3	3	11	14	452.134
#386	HMGA1	3	9	12	88.361
#387	FOXO3	3	9	12	2141.423
#388	RXRA	3	15	18	3192.211
#389	PPARG	3	10	13	318.399
#390	MLLT10	3	9	12	7018.625
#391	ZFP37	3	7	10	1101.262
#392	WNT5A	3	19	22	6422.866
#393	SMAD3	3	11	14	948.18
#394	NFE2L3	3	16	19	855.486
#395	HNRNPK	3	11	14	522.81
#396	NFYC	3	8	11	184.055
#397	EGR3	3	15	18	1542.849
#398	SUPT6H	3	4	7	132.265
#399	HOXB5	3	9	12	5844.984
#400	RUNX2	3	16	19	393.103
#401	CITED1	3	12	15	6888.866
#402	PURA	3	16	19	2279.502
#403	PLSCR1	3	10	13	1863.884
#404	SMAD4	3	14	17	294.216
#405	TP53	3	10	13	1359.305
#406	PEG3	3	16	19	5890.88
#407	NFIX	3	15	18	5788.653
#408	ZNF202	3	9	12	388.714
#409	POU4F3	3	12	15	133.739
#410	ZNF167	3	9	12	121.2
#411	MECOM	3	8	11	10781.642
#412	ATF6B	3	10	13	702.004
#413	MAFG	3	14	17	701.772
#414	TWIST1	3	13	16	2090.953
#415	NR2F1	3	16	19	2526.127
#416	SUPT4H1	3	16	19	10200.224
#417	VDR	2	13	15	660.268
#418	PBX3	2	13	15	1799.11
#419	MSX2	2	12	14	70.476
#420	TAF7	2	12	14	679.303
#421	CNBP	2	12	14	258.13
#422	ZNF323	2	8	10	161.879
#423	CNOT7	2	12	14	601.358
#424	RNF4	2	16	18	675.668
#425	BHLHE41	2	13	15	853.462
#426	ZNF85	2	12	14	517.433
#427	MYBL2	2	11	13	995.139
#428	DMRT1	2	10	12	407.564
#429	HNRNPAB	2	16	18	148.519
#430	IRF6	2	16	18	1617.839
#431	TADA3	2	9	11	370.809
#432	NFATC4	2	11	13	119.08
#433	HOXB7	2	11	13	2926.539
#434	HR	2	9	11	421.615
#435	ZHX2	2	12	14	760.864
#436	GATAD1	2	11	13	6385.956
#437	STAT2	2	7	9	33.937
#438	GATA2	2	18	20	2489.188
#439	IRF7	2	11	13	911.017
#440	SALL1	2	12	14	104.348
#441	SNAI2	2	11	13	133.369
#442	ESRRG	2	9	11	146.57
#443	FOXK2	2	16	18	538.33
#444	RARA	2	13	15	822.648
#445	TFDP2	2	10	12	121.717
#446	GATA4	2	9	11	30197.258
#447	SCML2	2	7	9	276.578
#448	CEBPD	2	16	18	4390.566
#449	MYNN	2	9	11	863.679
#450	RFXANK	2	16	18	707.893
#451	ZNF117	2	10	12	1712.343
#452	HEY1	2	14	16	1113.74
#453	C2orf3	2	11	13	1341.226
#454	MYCN	2	15	17	1303.766
#455	PPARA	2	12	14	594.06
#456	TLX2	2	14	16	211.559
#457	RUNX1	2	14	16	850.508
#458	SATB2	2	9	11	41.453
#459	FOSL2	2	13	15	1088.507
#460	BATF	2	11	13	2366.205
#461	HOXC10	2	14	16	605.275
#462	RORA	2	14	16	335.546
#463	TFAP2A	2	13	15	808.026
#464	KDM5A	1	11	12	409.251
#465	YEATS4	1	14	15	13.11
#466	SOLH	1	11	12	700.191
#467	ZNF274	1	9	10	24.416
#468	ATF5	1	9	10	189.736
#469	ASCL2	1	11	12	2270.694
#470	GTF2H4	1	9	10	44.681
#471	HSF2	1	12	13	578.82
#472	PITX2	1	13	14	90.426
#473	ETV5	1	7	8	67.219
#474	LHX1	1	11	12	197.777
#475	NR2C1	1	14	15	474.521
#476	EHF	1	21	22	1339.097
#477	NKX3-1	1	20	21	627.346
#478	ZNF80	1	15	16	119.488
#479	MITF	1	10	11	157.714
#480	PCGF2	1	17	18	83.178
#481	BCL6	1	17	18	1392.342
#482	WT1	1	11	12	1722.194
#483	SCAND2	1	12	13	73.708
#484	PHOX2A	1	10	11	180.617
#485	ZNF263	1	7	8	7.685
#486	UBN1	1	11	12	76.286
#487	ATF4	0	14	14	0
#488	CUX2	0	14	14	0
#489	SOX18	0	16	16	0
#490	SCML1	0	7	7	0
#491	RELA	0	12	12	0
#492	IRF5	0	8	8	0
#493	CSRNP2	0	10	10	0
#494	CTBP1	0	15	15	0
#495	BLZF1	0	13	13	0
#496	ASCL1	0	17	17	0
#497	POU1F1	0	7	7	0
#498	HOXA2	0	8	8	0
#499	ATF3	0	11	11	0
#500	HMGB1	0	13	13	0