Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MYBL2	80	2	82	125.071
#2	FOXM1	79	2	81	2809.596
#3	TCF21	74	5	79	628.991
#4	ERG	70	4	74	325.09
#5	FOXF1	69	5	74	400.993
#6	GATA6	66	10	76	8893.572
#7	PTTG1	62	6	68	392.427
#8	NR3C2	60	10	70	1789.715
#9	UHRF1	59	5	64	427.977
#10	E2F7	55	6	61	149.957
#11	MEF2A	55	5	60	159.464
#12	CSRNP1	55	4	59	99.498
#13	TBX5	55	3	58	72.934
#14	FLI1	53	6	59	153.628
#15	HES6	47	11	58	4370.768
#16	TRIM22	47	11	58	3127.52
#17	ETS2	46	8	54	1959.519
#18	SOX7	46	11	57	395.175
#19	HOPX	46	12	58	766.908
#20	ZEB1	45	4	49	36.163
#21	C5orf41	44	4	48	40.317
#22	CEBPD	43	9	52	395.214
#23	ONECUT2	42	9	51	20678.982
#24	TFAP2A	41	11	52	3147.713
#25	ARNTL2	41	13	54	2469.764
#26	TAL1	40	10	50	3114.38
#27	HMGA2	40	14	54	1836.182
#28	E2F8	39	10	49	672.471
#29	KLF2	39	5	44	179.985
#30	HLF	39	11	50	361.454
#31	FOSB	38	5	43	372.527
#32	PGR	37	12	49	519.345
#33	TCF3	36	11	47	441.773
#34	MTA3	36	9	45	380.787
#35	NFKB1	35	8	43	2013.859
#36	ZC3H8	34	10	44	541.232
#37	LASS6	34	13	47	2149.153
#38	HMGA1	34	10	44	139.274
#39	PKNOX2	32	12	44	11167.969
#40	RORA	32	14	46	673.282
#41	HOXA10	32	14	46	2893.153
#42	PITX2	31	14	45	10121.86
#43	ZNF238	30	15	45	8613.237
#44	SOX4	30	14	44	710.592
#45	IKZF1	30	3	33	89.756
#46	ZIC2	30	10	40	556.19
#47	FOXE1	29	12	41	8102.37
#48	NKX2-1	29	13	42	650.508
#49	TFDP2	28	9	37	103.009
#50	IRF8	28	4	32	650.986
#51	HDAC2	28	11	39	1013.471
#52	NR2F1	28	9	37	1548.427
#53	SMAD6	28	12	40	6221.379
#54	HOXA5	28	11	39	926.958
#55	KDM5B	28	9	37	13712.158
#56	PITX1	27	15	42	10402.512
#57	GTF2IRD1	27	11	38	1576.464
#58	ZFPM2	27	9	36	907.341
#59	FOXD1	27	13	40	6136.964
#60	SOX12	27	9	36	1890.421
#61	HOXA1	26	8	34	1070.642
#62	BCL3	26	8	34	423.341
#63	BNC1	26	10	36	428.276
#64	KLF9	26	15	41	1172.23
#65	ZEB2	26	9	35	2307.214
#66	MEF2C	26	10	36	341.418
#67	MAFF	25	9	34	4837.156
#68	JUNB	25	10	35	509.048
#69	IRF6	25	10	35	510.796
#70	RXRB	25	4	29	938.035
#71	TRIM29	24	8	32	182.845
#72	MITF	24	12	36	17228.5
#73	GAS7	24	14	38	1862.739
#74	ZHX2	24	13	37	2012.612
#75	MAX	24	4	28	794.618
#76	KLF6	24	12	36	970.766
#77	CNOT8	23	8	31	1391.178
#78	TBX3	23	7	30	3505.658
#79	RORC	23	11	34	453.355
#80	JDP2	23	10	33	192.84
#81	NR4A3	23	7	30	1142.634
#82	TP63	23	8	31	109.804
#83	KLF4	22	13	35	1742.235
#84	HCLS1	22	8	30	2540.342
#85	TBX2	22	13	35	423.922
#86	PA2G4	22	8	30	116.233
#87	PPARG	22	15	37	2166.145
#88	NFIX	22	17	39	670.737
#89	TGIF2	22	17	39	1775.819
#90	DLX6	22	14	36	13491.535
#91	CREB1	22	2	24	46.44
#92	RELB	21	10	31	2479.121
#93	ATF1	21	4	25	604.555
#94	SOX2	21	21	42	806.378
#95	C11orf9	21	19	40	2774.945
#96	NFYC	21	1	22	18.674
#97	CEBPB	21	13	34	1163.159
#98	PRDM2	21	8	29	548.7
#99	NFIL3	21	7	28	509.217
#100	RELA	20	8	28	736.635
#101	GABPB1	20	15	35	894.199
#102	HOXB7	20	16	36	874.888
#103	SNAI2	20	10	30	1201.071
#104	PEG3	20	13	33	2830.516
#105	TWIST1	20	19	39	728.089
#106	GATAD2B	20	9	29	601.124
#107	ATF2	20	8	28	766.667
#108	MEIS2	19	17	36	5990.15
#109	E2F2	19	6	25	238.133
#110	ETV1	19	13	32	1501.784
#111	RXRA	19	17	36	3179.141
#112	PROX1	19	13	32	1932.935
#113	CITED2	19	14	33	5699.712
#114	TFAP2C	19	17	36	2235.408
#115	CREB5	19	9	28	267.569
#116	STAT4	19	7	26	145.954
#117	MMP14	19	15	34	2834.809
#118	E2F3	19	12	31	877.251
#119	ENO1	19	8	27	2203.435
#120	HOXC9	19	8	27	3067.837
#121	CBFA2T2	18	14	32	337.425
#122	SP140	18	4	22	195.516
#123	NFIC	18	11	29	1979.974
#124	TCF19	18	7	25	400.444
#125	GTF2I	18	6	24	1762.808
#126	ARID4A	18	10	28	674.679
#127	TSHZ3	18	11	29	1447.182
#128	SIX4	18	16	34	429.475
#129	YEATS4	18	11	29	837.991
#130	IRF1	18	13	31	1039.121
#131	SMAD9	17	21	38	1165.781
#132	DMRT2	17	13	30	3141.735
#133	MSX2	17	11	28	2587.183
#134	MYT1	17	8	25	10145.156
#135	ST18	17	7	24	1388.83
#136	GATA2	17	13	30	80.74
#137	REL	17	10	27	1633.517
#138	NOLC1	17	12	29	1423.568
#139	PBX1	17	18	35	959.999
#140	HOXA4	17	11	28	759.741
#141	AFF4	17	10	27	576.117
#142	GLIS2	17	16	33	1392.174
#143	BACH1	17	18	35	1555.806
#144	ZNF167	17	17	34	2807.916
#145	ZNF92	17	12	29	2367.53
#146	MEIS1	17	12	29	340.183
#147	NEUROD1	17	8	25	597.407
#148	HOXD10	17	15	32	1442.557
#149	NR3C1	17	18	35	1408.413
#150	TAF12	16	10	26	706.978
#151	MLLT10	16	8	24	1509.416
#152	NFXL1	16	15	31	974.328
#153	THRB	16	12	28	187.365
#154	ZNF643	16	20	36	1380.784
#155	ATF5	16	18	34	2277.749
#156	ETV4	16	19	35	2731.799
#157	EBF1	16	18	34	382.578
#158	MAFG	16	14	30	1834.018
#159	ZKSCAN4	16	12	28	824.243
#160	L3MBTL4	16	19	35	1376.421
#161	TBX15	16	13	29	3427.862
#162	NFATC1	16	15	31	9768.872
#163	MAFK	16	13	29	1158.823
#164	FOSL1	16	12	28	2390.193
#165	FOSL2	16	12	28	2382.816
#166	MEOX2	16	13	29	926.163
#167	NR4A1	16	5	21	804.44
#168	JUND	15	10	25	735.723
#169	ASCL1	15	16	31	5014.327
#170	ZFP36L2	15	8	23	585.297
#171	RUNX2	15	12	27	925.517
#172	LEF1	15	19	34	888.793
#173	TCF7L2	15	15	30	1190.523
#174	DLX2	15	12	27	1315.737
#175	HMGB2	15	10	25	140.911
#176	HNF4G	15	16	31	4472.056
#177	LHX2	15	15	30	5328.48
#178	TBX4	15	8	23	302.34
#179	CREBL2	15	11	26	1185.535
#180	ERF	15	12	27	901.266
#181	HOXD11	15	10	25	152.551
#182	E2F1	15	12	27	193.23
#183	NFIA	14	19	33	2771.925
#184	MECOM	14	17	31	1580.205
#185	EPAS1	14	12	26	2346.012
#186	TSHZ1	14	17	31	3089.739
#187	MXD1	14	15	29	2440.263
#188	PAX6	14	21	35	2997.997
#189	ZNF3	14	14	28	882.205
#190	RERE	14	3	17	552.677
#191	C2orf3	14	14	28	260.523
#192	FOXO6	14	15	29	2283.483
#193	TFAM	14	14	28	1532.791
#194	MSC	14	17	31	1607.315
#195	ATF3	14	6	20	708.286
#196	TRIM28	14	11	25	429.818
#197	KLF10	14	8	22	291.004
#198	FOXN3	14	11	25	1331.331
#199	SPI1	14	13	27	1097.837
#200	FOXP1	14	16	30	1123.64
#201	POU6F1	13	15	28	541.617
#202	ZNF138	13	13	26	660.688
#203	MSRB2	13	15	28	2225.783
#204	ZSCAN2	13	12	25	190.488
#205	NFE2L3	13	17	30	518.096
#206	CREM	13	7	20	8205.575
#207	ESRRG	13	24	37	1399.707
#208	POU2F3	13	10	23	1167.644
#209	SOX17	13	13	26	7121.87
#210	SOX11	13	19	32	2647.413
#211	IRX2	13	20	33	963.625
#212	FOXK2	13	18	31	1402.84
#213	FOXG1	13	18	31	3960.061
#214	LMO4	13	16	29	1534.216
#215	SCAND3	13	18	31	5086.979
#216	HMG20B	13	6	19	253.523
#217	MTA1	13	15	28	323.406
#218	TFEC	13	8	21	521.783
#219	GLI3	13	13	26	1828.667
#220	FOXF2	13	11	24	307.361
#221	JUN	12	11	23	202.074
#222	MYNN	12	13	25	1501.549
#223	VAV1	12	8	20	310.693
#224	SALL1	12	16	28	6514.093
#225	ELK3	12	14	26	6786.316
#226	KLF11	12	18	30	1694.977
#227	HIC1	12	19	31	694.87
#228	CBFA2T3	12	11	23	64.023
#229	TFCP2	12	13	25	1184.098
#230	RUNX1T1	12	14	26	771.024
#231	ZNF281	12	13	25	2401.871
#232	CTNNB1	12	14	26	1030.512
#233	NFE2L2	12	16	28	3774.221
#234	AHR	12	22	34	4269.245
#235	GRHL3	12	12	24	750.348
#236	ZNF367	12	9	21	466.413
#237	HOXB3	12	15	27	3186.965
#238	CREB3L4	11	15	26	838.055
#239	HOXC4	11	14	25	738.611
#240	NFKB2	11	12	23	1343.35
#241	SOX15	11	17	28	299.737
#242	SOX18	11	14	25	2494.567
#243	DLX1	11	16	27	879.577
#244	IKZF4	11	18	29	906.173
#245	FUBP1	11	20	31	1719.425
#246	HOXD13	11	19	30	887.551
#247	NR1H3	11	7	18	980.153
#248	HOXB6	11	15	26	4155.976
#249	MAFB	11	12	23	383.215
#250	TSC22D3	11	15	26	300.068
#251	ETS1	11	10	21	786.747
#252	SMAD5	11	9	20	803.021
#253	FOS	11	9	20	303.603
#254	HOXC10	11	16	27	3586.862
#255	ZHX3	11	10	21	49.985
#256	ZNF639	10	12	22	1052.338
#257	BARX1	10	19	29	1477.454
#258	TCEAL1	10	12	22	409.661
#259	ZNF148	10	6	16	56.684
#260	SPDEF	10	11	21	1417.831
#261	EN1	10	14	24	1070.332
#262	IRF4	10	8	18	2655.259
#263	NFYA	10	16	26	1146.905
#264	POU3F2	10	16	26	2647.525
#265	ZSCAN18	10	16	26	742.002
#266	ASCL2	10	14	24	542.098
#267	FOXO1	10	17	27	2110.106
#268	TULP4	10	14	24	816.392
#269	ZSCAN16	10	19	29	1672.221
#270	POU2F2	10	14	24	1763.361
#271	SIX1	10	16	26	650.633
#272	IRX3	10	13	23	613.461
#273	MEIS3P1	10	17	27	1685.571
#274	POU4F1	10	19	29	3457.563
#275	BHLHE40	10	16	26	736.297
#276	FOXA2	10	16	26	910.21
#277	GTF2H2	10	15	25	776.636
#278	ESR1	10	27	37	10448.667
#279	BATF	9	18	27	3177.02
#280	NFAT5	9	10	19	666.129
#281	MYCL1	9	20	29	863.272
#282	RUNX3	9	15	24	1479.082
#283	ZNF277	9	7	16	379.791
#284	TRPS1	9	18	27	1231.739
#285	SLC2A4RG	9	11	20	676.787
#286	NR1H2	9	16	25	737.335
#287	TRIM25	9	15	24	265.543
#288	HOXA3	9	17	26	1201.724
#289	TARDBP	9	18	27	1049.588
#290	SP1	9	13	22	1212.617
#291	STAT6	9	11	20	1002.127
#292	SIX2	9	19	28	1875.307
#293	CEBPA	9	19	28	1330.822
#294	PCGF2	9	14	23	600.309
#295	SATB1	9	20	29	805.638
#296	EOMES	9	7	16	1988.322
#297	NR2F6	9	17	26	1077.276
#298	YBX1	9	6	15	306.899
#299	HOXD1	9	18	27	2614.33
#300	ZNF217	9	16	25	557.657
#301	TWIST2	9	13	22	778.798
#302	NR0B1	9	18	27	9075.227
#303	HEYL	9	18	27	327.006
#304	EGR3	9	6	15	1416.453
#305	BCL6	9	10	19	806.454
#306	TEF	8	11	19	1280.838
#307	HOXA9	8	15	23	1016.452
#308	GATA3	8	18	26	2466.965
#309	SATB2	8	22	30	1038.092
#310	SPIB	8	11	19	1938.994
#311	CSRNP3	8	14	22	1087.569
#312	KLF15	8	8	16	63.136
#313	BATF2	8	12	20	1311.307
#314	HOXB2	8	13	21	1709.633
#315	PURB	8	10	18	1193.97
#316	ZFP42	8	18	26	1495.677
#317	LCOR	8	17	25	1613.825
#318	SOX13	8	22	30	4306.95
#319	BATF3	8	21	29	1301.937
#320	HEY2	8	16	24	449.386
#321	WNT5A	8	13	21	2572.084
#322	SALL2	8	20	28	6902.97
#323	HIF3A	8	21	29	759.979
#324	ZNF397	8	13	21	847.411
#325	MNX1	8	17	25	3035.672
#326	ELF3	8	24	32	1397.607
#327	PURA	8	13	21	2652.841
#328	CDKN2A	8	21	29	109.78
#329	NFYB	8	14	22	1741.782
#330	CLOCK	8	13	21	3974.827
#331	SCAND1	8	13	21	334.47
#332	ZFHX4	8	18	26	659.818
#333	ZNF232	8	16	24	3756.857
#334	NANOGNB	8	12	20	437.149
#335	PRDM1	8	17	25	1276.724
#336	RCAN1	8	14	22	950.144
#337	TFAP2B	8	14	22	732.929
#338	HOXA2	8	13	21	1107.427
#339	NKX3-1	7	14	21	222.084
#340	BACH2	7	22	29	1896.973
#341	HHEX	7	15	22	327.119
#342	HOXD4	7	20	27	1155.048
#343	IRX1	7	21	28	351.863
#344	SMAD3	7	20	27	526.636
#345	OVOL1	7	19	26	1230.782
#346	KLF5	7	15	22	880.871
#347	HNF1B	7	13	20	358.784
#348	TFEB	7	16	23	916.847
#349	SIX3	7	12	19	1564.209
#350	FOXA1	7	23	30	1882.489
#351	PBX3	7	21	28	451.276
#352	ZNF117	7	22	29	1533.853
#353	NR5A2	7	13	20	1388.616
#354	PLSCR1	7	16	23	1512.426
#355	NR2F2	7	19	26	250.559
#356	CBFB	7	9	16	429.397
#357	DDIT3	7	18	25	431.79
#358	XBP1	7	12	19	665.056
#359	TFDP1	7	17	24	1052.188
#360	ZBTB38	7	11	18	830.334
#361	FOXL1	7	14	21	422.716
#362	STAT3	7	18	25	1142.232
#363	CREB3L2	7	18	25	1068.72
#364	ZNF93	7	23	30	346.005
#365	ELF1	7	11	18	688.299
#366	MSX1	7	19	26	9388.859
#367	ZFHX3	6	14	20	2898.826
#368	SOX9	6	23	29	1752.907
#369	PHF5A	6	12	18	278.902
#370	TCFL5	6	20	26	1261.628
#371	C1orf85	6	24	30	961.596
#372	TCF12	6	15	21	860.114
#373	ZKSCAN1	6	16	22	626.852
#374	CUX1	6	17	23	2085.85
#375	ZNF91	6	23	29	4025.841
#376	BCL11B	6	18	24	557.535
#377	E2F5	6	19	25	1020.051
#378	ARNT	6	8	14	394.023
#379	AHCTF1	6	22	28	1291.504
#380	EHF	6	20	26	686.085
#381	CREB3L1	6	19	25	663.413
#382	NFE2	6	19	25	344.229
#383	NFIB	6	25	31	381.179
#384	SCML1	6	20	26	522.869
#385	MEOX1	6	20	26	1258.149
#386	TAF5	6	21	27	1032.062
#387	PLAG1	6	24	30	2803.764
#388	FOXA3	6	14	20	959.269
#389	CBL	6	14	20	955.523
#390	IRF9	6	19	25	569.262
#391	NFATC2	6	15	21	570.671
#392	ARNT2	6	18	24	3596.044
#393	SOX6	6	23	29	3894.988
#394	GRHL2	5	16	21	908.465
#395	SLC30A9	5	20	25	1138.774
#396	TBX21	5	12	17	1402.13
#397	TCF15	5	15	20	884.186
#398	MBD1	5	17	22	1427.734
#399	KLF3	5	14	19	446.68
#400	FOXP4	5	17	22	734.574
#401	WT1	5	18	23	507.065
#402	AEBP1	5	15	20	2747.5
#403	BHLHE41	5	15	20	1534.855
#404	STAT1	5	17	22	896.124
#405	NFATC3	5	13	18	432.748
#406	SMAD4	5	12	17	538.687
#407	KLF12	5	16	21	302.885
#408	HEY1	5	20	25	983.182
#409	ZNF256	5	19	24	1109.29
#410	SPEN	5	11	16	256.185
#411	FOXC1	5	23	28	947.788
#412	BTG2	5	17	22	1432.518
#413	FOXJ1	5	16	21	361.47
#414	VDR	5	22	27	1619.687
#415	HMBOX1	5	17	22	2147.077
#416	TAF4B	5	24	29	611.065
#417	MESP1	5	19	24	188.7
#418	EGR2	5	15	20	1070.016
#419	CREBZF	5	16	21	905.251
#420	MLL	4	14	18	798.054
#421	TEAD2	4	17	21	1018.965
#422	SREBF1	4	18	22	1349.424
#423	TCF7L1	4	23	27	1858.099
#424	RUNX1	4	16	20	151.024
#425	ETV5	4	21	25	179.334
#426	ZNF24	4	15	19	159.456
#427	ZFP90	4	14	18	748.291
#428	TFAP2D	4	13	17	4715.628
#429	HES1	4	22	26	1948.384
#430	IRF7	4	16	20	363.331
#431	CSDA	4	20	24	439.362
#432	TSC22D1	4	23	27	1536.879
#433	VTN	4	20	24	439.524
#434	ZHX1	4	20	24	3602.736
#435	HIRA	4	15	19	879.208
#436	TSHZ2	4	16	20	811.231
#437	PBX2	4	13	17	1559.356
#438	ZNF83	4	18	22	1021.62
#439	PRRX1	4	20	24	310.908
#440	RBCK1	3	19	22	291.179
#441	ISL1	3	16	19	510.423
#442	KLF7	3	17	20	684.122
#443	FOXC2	3	17	20	3835.504
#444	HOXD8	3	20	23	320.561
#445	MAF	3	29	32	743.071
#446	HOXA7	3	14	17	429.567
#447	ZIC1	3	21	24	226.584
#448	MYCN	3	21	24	1447.823
#449	TBX1	3	19	22	674.816
#450	EGR1	3	12	15	48.355
#451	IRX5	3	14	17	372.578
#452	TEAD4	3	22	25	734.318
#453	TSC22D2	3	16	19	1495.247
#454	ZNF165	3	19	22	383.131
#455	MYC	3	11	14	217.55
#456	ZNF268	3	17	20	975.669
#457	ZNF323	3	18	21	3469.455
#458	SOLH	3	20	23	919.844
#459	LHX9	3	20	23	491.698
#460	CNOT7	3	19	22	654.523
#461	RHOXF1	3	2	5	20.646
#462	LHX6	2	15	17	30.285
#463	IRF5	2	23	25	5524.375
#464	TRERF1	2	18	20	249.685
#465	FOXP2	2	24	26	549.157
#466	RARB	2	22	24	537.467
#467	ETV6	2	24	26	608.306
#468	SIN3A	2	18	20	34.93
#469	DBP	2	19	21	146.429
#470	NR4A2	2	10	12	29.31
#471	GATA5	2	17	19	1060.572
#472	CITED1	2	15	17	274.482
#473	GLIS3	2	18	20	1670.4
#474	ZNF215	2	18	20	160.254
#475	NPAS2	2	20	22	824.156
#476	FOXQ1	2	27	29	591.05
#477	TP53	1	16	17	65.458
#478	TCF4	1	24	25	2202.346
#479	ZNF131	1	20	21	103.35
#480	PAX7	1	14	15	1743.554
#481	ZNF207	1	19	20	228.732
#482	NR1D2	1	26	27	46.016
#483	PHOX2B	1	8	9	81.787
#484	ZFP36L1	1	26	27	141.834
#485	ELF5	1	21	22	35.454
#486	CTBP1	1	25	26	52.786
#487	ARX	1	25	26	237.316
#488	TFCP2L1	1	20	21	1336.5
#489	FOXO3	1	12	13	92.779
#490	GLI2	1	14	15	1058.421
#491	ATF6	1	21	22	35.841
#492	FOXK1	0	18	18	0
#493	ZXDC	0	22	22	0
#494	SMAD1	0	21	21	0
#495	TGIF1	0	19	19	0
#496	RARA	0	20	20	0
#497	HOXB5	0	20	20	0
#498	MGA	0	24	24	0
#499	DLX4	0	19	19	0
#500	ARNTL	0	13	13	0