Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HHEX	50	6	56	1568.31
#2	EBF1	46	3	49	684.152
#3	AFF4	46	0	46	0
#4	FOXO1	41	4	45	489.876
#5	ATF1	39	0	39	0
#6	MEF2C	39	1	40	20.795
#7	MEF2A	38	8	46	1768.935
#8	C5orf41	36	3	39	913.11
#9	CSRNP1	35	4	39	1876.143
#10	TAF4	34	6	40	613.716
#11	PKNOX1	34	7	41	1086.349
#12	SP3	34	6	40	1683.158
#13	BCL11B	33	5	38	83.613
#14	SPDEF	32	3	35	1621.076
#15	TCF4	31	3	34	413
#16	CREBBP	31	5	36	2671.175
#17	ELK3	30	6	36	1099.053
#18	ZNF639	30	4	34	1348.023
#19	TFEB	30	5	35	1894.268
#20	HMG20A	29	6	35	1560.988
#21	POU5F1B	29	2	31	108.702
#22	CTCF	28	8	36	4317.453
#23	IRF2	28	6	34	1149.774
#24	ATF2	28	5	33	1061.336
#25	NCOR1	26	9	35	4813.504
#26	ZXDC	25	7	32	6533.28
#27	HIRA	25	7	32	6241.839
#28	TCF7	25	6	31	2164.83
#29	ZNF281	25	4	29	372.837
#30	ZNF92	25	9	34	4292.032
#31	CREBL2	24	6	30	2840.016
#32	NFYB	24	10	34	1784.048
#33	MAX	24	5	29	1976.221
#34	CSDA	24	11	35	8760.305
#35	DLX2	24	4	28	1052.762
#36	TCF3	23	5	28	549.038
#37	ZSCAN16	23	8	31	1516.563
#38	BACH1	23	6	29	340.337
#39	SLC30A9	22	7	29	1709.393
#40	ZNF394	22	4	26	841.173
#41	GABPA	22	4	26	1770.534
#42	TFDP2	22	8	30	8419.932
#43	PPARD	21	9	30	1629.15
#44	ETS1	21	9	30	1874.583
#45	ZNF75D	21	8	29	1206.8
#46	ZNF236	21	6	27	2796.96
#47	NFKB1	20	9	29	2538.62
#48	TAF12	20	6	26	1270.716
#49	IRX3	20	9	29	4567.161
#50	ZNF187	20	6	26	588.586
#51	ELF2	20	8	28	2782.637
#52	SCML2	20	11	31	2120.592
#53	KLF16	20	4	24	196.369
#54	PCGF2	20	4	24	311.877
#55	GATA3	20	8	28	543.724
#56	ZHX2	20	6	26	422.502
#57	HNRNPAB	20	9	29	6115.808
#58	BLZF1	19	5	24	1186.341
#59	SNAPC5	19	10	29	1646.638
#60	RFXAP	19	7	26	981.117
#61	ZKSCAN1	19	9	28	1477.366
#62	PRDM2	19	8	27	409.249
#63	HIF1A	19	8	27	685.105
#64	ZNF274	19	10	29	6334.569
#65	C11orf9	19	3	22	170.588
#66	TCFL5	18	8	26	670.723
#67	RERE	18	8	26	1774.235
#68	SMAD2	18	7	25	944.392
#69	ZKSCAN5	18	6	24	336.41
#70	RCOR2	18	3	21	689.893
#71	FOSL2	18	8	26	890.314
#72	CBFA2T3	18	9	27	2232.09
#73	SOX15	17	0	17	0
#74	E2F4	17	3	20	789.847
#75	MESP1	17	4	21	469.993
#76	NFYC	17	11	28	2329.757
#77	TSC22D3	17	7	24	1310.419
#78	IRX5	17	6	23	1154.851
#79	NR2C1	17	10	27	3041.5
#80	JUNB	17	3	20	79.661
#81	ELK1	17	5	22	848.678
#82	TCF12	17	11	28	1596.954
#83	TFCP2	17	13	30	1861.501
#84	MSRB2	17	9	26	3520.151
#85	REL	16	10	26	1385.446
#86	CREB3L4	16	13	29	3435.045
#87	TGIF1	16	11	27	752.705
#88	ARID4A	16	8	24	2306.428
#89	KLF11	16	9	25	1469.904
#90	MGA	16	8	24	476.668
#91	BACH2	16	7	23	248.929
#92	HMX1	16	8	24	567.28
#93	ZXDA	16	10	26	1093.329
#94	TSC22D2	16	8	24	1464.216
#95	TEAD2	16	2	18	236.31
#96	IRF7	15	11	26	1171.399
#97	REST	15	3	18	90.926
#98	ZC3H8	15	11	26	3497.128
#99	STRN3	15	8	23	1252.768
#100	TCEAL1	15	13	28	2142.325
#101	PURA	15	10	25	2764.49
#102	ZNF444	15	6	21	6139.329
#103	RAX2	15	6	21	735.41
#104	HNF1B	15	6	21	257.789
#105	ZBTB48	15	10	25	2153.636
#106	SNAPC2	15	4	19	816.552
#107	CREB3L2	15	11	26	1398.917
#108	NFXL1	15	4	19	544.535
#109	ARX	15	5	20	113.223
#110	MEIS3P1	14	8	22	468.481
#111	RORA	14	12	26	1504.399
#112	GTF2IRD1	14	11	25	768.964
#113	MAFF	14	11	25	950.909
#114	ADNP2	14	11	25	1176.67
#115	TAF5L	14	4	18	1095.41
#116	GATAD1	14	14	28	3227.345
#117	CIR1	14	12	26	2920.063
#118	CBL	13	10	23	1999.687
#119	ALS2CR8	13	10	23	735.477
#120	NR1D2	13	11	24	3753.961
#121	HEY2	13	12	25	2003.986
#122	ZNF83	13	8	21	3700.421
#123	ZNF367	13	13	26	4756.978
#124	IRF3	13	7	20	908.23
#125	ERG	13	13	26	1882.651
#126	TP53	13	9	22	784.764
#127	MXD1	13	5	18	755.155
#128	ZEB2	13	11	24	610.664
#129	ZFPM1	13	5	18	1002.239
#130	FOXJ3	13	6	19	4560.852
#131	GABPB1	13	13	26	3674.149
#132	ZNF81	13	4	17	96.623
#133	PLSCR1	13	14	27	1100.273
#134	TCF7L2	13	9	22	5900.759
#135	TFAM	13	7	20	3938.766
#136	LMO4	12	10	22	769.725
#137	ELK4	12	9	21	2121.463
#138	ZNF496	12	9	21	1433.021
#139	FOXM1	12	6	18	1401.307
#140	HOXA7	12	6	18	1559.565
#141	NPAT	12	9	21	882.337
#142	ZNF117	12	15	27	1522.995
#143	RELA	12	13	25	1275.422
#144	HDAC1	12	14	26	2775.7
#145	NR1H3	12	6	18	633.008
#146	ZNF140	12	7	19	487.49
#147	MTA3	12	8	20	6551.215
#148	TAF4B	12	12	24	653.301
#149	FOXO4	12	3	15	3119.764
#150	DBP	12	16	28	2740.601
#151	CNOT7	12	10	22	1158.371
#152	HMG20B	12	9	21	2771.347
#153	IRF8	12	10	22	419.971
#154	CREB1	12	8	20	977.866
#155	MEOX1	12	9	21	2522.747
#156	NOTCH1	12	8	20	728.628
#157	TLX3	12	11	23	2262.068
#158	RB1	12	7	19	1495.555
#159	ESR1	11	6	17	885.496
#160	NR4A3	11	9	20	653.442
#161	ST18	11	11	22	1498.945
#162	ETV5	11	14	25	8290.552
#163	BTG2	11	9	20	1846.459
#164	SPIB	11	9	20	4865.673
#165	KLF7	11	10	21	722.423
#166	RBPJ	11	8	19	537.983
#167	IRF1	11	7	18	418.946
#168	ZFP90	11	13	24	3604.689
#169	CREBZF	11	13	24	2946.79
#170	CREM	11	11	22	4001.717
#171	HDAC2	11	9	20	363.888
#172	ZNF134	11	6	17	1317.589
#173	RELB	11	10	21	1326.491
#174	RORC	11	13	24	1517.916
#175	BRD8	11	10	21	755.527
#176	ZNF189	11	10	21	1209.845
#177	GTF2H4	11	14	25	1017.216
#178	PHF1	11	10	21	607.658
#179	DMTF1	11	11	22	1565.902
#180	RFX5	11	9	20	754.395
#181	RXRB	10	14	24	842.548
#182	FOXK2	10	13	23	3784.547
#183	TSHZ1	10	12	22	1340.137
#184	TRIM28	10	10	20	4253.888
#185	TFE3	10	10	20	1500.31
#186	LCOR	10	13	23	1146.808
#187	AHR	10	19	29	5538.161
#188	YEATS4	10	12	22	1675.925
#189	TCF15	10	5	15	134.091
#190	AHCTF1	10	9	19	1412.447
#191	CUX1	10	11	21	1154.812
#192	FOXP3	10	7	17	400.283
#193	KLF9	10	17	27	2043.697
#194	KLF3	10	10	20	775.076
#195	C2orf3	10	13	23	885.557
#196	SIN3A	10	10	20	1781.643
#197	ZNF397	10	11	21	2813.123
#198	RARG	10	9	19	2301.08
#199	ATF6	10	11	21	1112.349
#200	TAF13	10	9	19	709.037
#201	CSRNP2	10	12	22	879.753
#202	E2F3	10	14	24	3219.841
#203	ZEB1	9	15	24	2732.57
#204	TAL1	9	7	16	985.047
#205	ZNF483	9	6	15	1781.342
#206	NFIL3	9	13	22	1983.302
#207	CNOT8	9	9	18	847.76
#208	STAT2	9	13	22	1804.732
#209	MYOG	9	4	13	2063.348
#210	STAT4	9	13	22	3174.568
#211	GATAD2A	9	12	21	4151.194
#212	ZNF277	9	7	16	949.651
#213	ZNF131	9	17	26	3744.101
#214	MTF1	9	12	21	569.731
#215	HMGB2	9	12	21	1276.634
#216	CBFB	9	10	19	2504.187
#217	BCL3	9	14	23	1353.311
#218	GTF2H3	9	10	19	683.904
#219	SATB1	9	12	21	2924.566
#220	PGBD1	9	10	19	440.724
#221	USF2	9	6	15	447.306
#222	ZNF256	9	11	20	8104.437
#223	XBP1	9	6	15	753.785
#224	ZNF45	9	9	18	1005.58
#225	SALL2	9	9	18	180.501
#226	E2F7	9	11	20	825.108
#227	ZNF202	9	16	25	2320.494
#228	RNF4	9	9	18	1241.818
#229	MLXIPL	9	6	15	293.288
#230	E2F6	9	11	20	1336.769
#231	TAF5	9	8	17	599.819
#232	PTTG1	9	5	14	399.266
#233	E2F1	8	9	17	557.694
#234	NR3C2	8	10	18	3483.26
#235	ETS2	8	11	19	646.694
#236	GATA1	8	2	10	283.967
#237	PA2G4	8	10	18	937.03
#238	HOXA10	8	2	10	182.753
#239	ARNT	8	15	23	5668.395
#240	MEF2D	8	7	15	266.969
#241	FOXL1	8	9	17	2375.542
#242	ZSCAN21	8	12	20	1351.635
#243	ZNF138	8	8	16	1035.994
#244	CITED2	8	16	24	5617.401
#245	DDIT3	8	8	16	517.381
#246	SOX7	8	14	22	1095.559
#247	ETV3	8	16	24	2202
#248	STAT3	8	12	20	2009.43
#249	PLAGL2	8	16	24	2168.456
#250	RUNX3	8	10	18	1141.868
#251	ADNP	8	10	18	841.88
#252	LEF1	8	8	16	4967.409
#253	ZNF217	8	10	18	437.103
#254	GTF2H2	8	9	17	1210.279
#255	ZKSCAN4	8	14	22	1692.189
#256	ATF3	8	7	15	721.897
#257	E2F8	8	5	13	579.437
#258	NR4A1	8	9	17	1027.402
#259	FUBP1	8	16	24	3717.991
#260	CEBPD	8	11	19	560.589
#261	ZFHX3	8	13	21	512.951
#262	KLF4	8	19	27	2857.709
#263	UBN1	8	14	22	1250.439
#264	TFEC	8	9	17	1974.999
#265	IKZF1	8	10	18	305.641
#266	C1orf85	8	10	18	2377.069
#267	FOXN3	8	10	18	894.748
#268	KLF10	8	13	21	1448.789
#269	ZNF232	7	12	19	2575.636
#270	ZNF175	7	10	17	5228.158
#271	UBP1	7	13	20	1068.228
#272	NKX3-2	7	16	23	1841.147
#273	TARDBP	7	11	18	983.496
#274	SIX6	7	6	13	653.404
#275	MYCN	7	11	18	1462.714
#276	HNF1A	7	5	12	848.501
#277	SMAD4	7	13	20	1928.77
#278	ZNF24	7	8	15	1206.317
#279	ZNF238	7	11	18	805.756
#280	JUND	7	13	20	1248.093
#281	ZRANB2	7	12	19	1239.536
#282	HES1	7	15	22	724.208
#283	NKX3-1	7	15	22	999.217
#284	NR3C1	7	10	17	875.809
#285	JUN	7	15	22	2060.782
#286	GTF2I	7	8	15	584.012
#287	ENO1	7	16	23	2668.313
#288	KDM5B	7	11	18	1954.801
#289	HMGB1	7	6	13	994.621
#290	TAF7	7	8	15	1728.227
#291	PURB	7	9	16	519.216
#292	FOXP1	7	10	17	478.13
#293	IRF4	7	8	15	401.361
#294	SOX6	7	8	15	1747.988
#295	ELF1	7	13	20	401.967
#296	NR4A2	7	15	22	1986.17
#297	FOXO3	7	13	20	990.954
#298	ZNF193	6	17	23	4223.227
#299	NFIC	6	8	14	1825.417
#300	ZNF445	6	8	14	892.265
#301	FOXK1	6	11	17	4375.05
#302	NFAT5	6	11	17	1083.101
#303	PHTF1	6	10	16	2579.533
#304	POU2F2	6	8	14	212.521
#305	HSF2	6	11	17	2368.684
#306	CTNNB1	6	14	20	1179.304
#307	RCOR1	6	12	18	528.29
#308	SREBF2	6	13	19	1247.121
#309	TLX1	6	7	13	879.589
#310	TAF1B	6	10	16	445.895
#311	TRIM25	6	11	17	3152.076
#312	TADA3	6	7	13	2790.138
#313	MLL	6	10	16	1028.026
#314	TRIM22	6	13	19	1260.874
#315	PRDM1	6	13	19	1351.106
#316	ZNF3	6	12	18	787.513
#317	FOXN2	6	11	17	811.24
#318	UHRF1	6	15	21	4402.304
#319	ZNF70	6	8	14	165.452
#320	LZTS1	6	12	18	781.059
#321	IRF9	6	8	14	652.814
#322	ETV6	6	12	18	480.581
#323	BHLHE40	6	18	24	5872.181
#324	CREB3L3	6	7	13	816.985
#325	HOXA5	6	8	14	742.832
#326	FOSB	6	7	13	1507.448
#327	NOLC1	6	11	17	349.364
#328	MAF	6	15	21	1910.285
#329	ZNF148	6	14	20	2377.632
#330	SATB2	6	8	14	6082.204
#331	EVX1	6	9	15	6970.267
#332	CEBPB	6	21	27	5918.577
#333	HOXC4	6	12	18	2293.472
#334	SPI1	6	9	15	456.04
#335	NR2C2	6	12	18	1480.105
#336	POU6F1	6	6	12	482.626
#337	NR1H2	6	12	18	328.773
#338	PROX1	5	13	18	5361.646
#339	STAT5A	5	9	14	8681.324
#340	ASCL2	5	8	13	467.304
#341	FBXW7	5	11	16	929.605
#342	SNAI2	5	8	13	353.197
#343	ZNF628	5	9	14	2120.482
#344	SMAD1	5	18	23	1487.286
#345	EGR1	5	12	17	1761.181
#346	CDKN2A	5	10	15	452.306
#347	FOS	5	11	16	1655.397
#348	SMAD6	5	14	19	2442.874
#349	ZNF498	5	12	17	674.145
#350	CCRN4L	5	9	14	1814.637
#351	SCML1	5	12	17	1334.704
#352	HMX2	5	10	15	1425.789
#353	SOX4	5	13	18	2950.119
#354	ELF4	5	10	15	730.187
#355	SP140	5	15	20	1071.189
#356	KLF6	5	7	12	827.348
#357	FLI1	5	13	18	3229.65
#358	HEY1	5	10	15	609.458
#359	KLF12	5	14	19	777.678
#360	FOXF1	5	6	11	1462.05
#361	ZNF207	5	13	18	1948.941
#362	ZNF167	5	13	18	884.787
#363	KLF2	5	13	18	800.393
#364	SP4	5	12	17	832.046
#365	ZFP36L2	5	11	16	1101.829
#366	VAV1	5	14	19	1609.362
#367	ZSCAN18	5	13	18	977.103
#368	PBX2	5	10	15	426.852
#369	NFKB2	5	11	16	7660.743
#370	ZNF33A	5	7	12	912.866
#371	TWIST1	5	10	15	577.877
#372	MSL3	5	13	18	1312.081
#373	EPAS1	5	18	23	2951.081
#374	ETV7	5	7	12	125.434
#375	MMP14	5	8	13	334.006
#376	PBX3	5	15	20	1003.167
#377	AEBP1	5	13	18	2906.833
#378	BTAF1	5	10	15	554.006
#379	MEIS2	5	11	16	3878.074
#380	SMAD9	5	7	12	2613.682
#381	TFAP2C	4	4	8	63.281
#382	ZSCAN12	4	9	13	434.902
#383	HSF1	4	10	14	1616.295
#384	NFE2L2	4	16	20	3735.941
#385	JDP2	4	18	22	1219.8
#386	SRY	4	12	16	3097.831
#387	E2F2	4	12	16	2117.505
#388	RXRA	4	12	16	1232.224
#389	MYBL2	4	11	15	532.019
#390	TBX21	4	11	15	1834.169
#391	TRERF1	4	11	15	273.851
#392	ZNF91	4	14	18	2060.069
#393	HMGA1	4	10	14	3158.866
#394	GCFC1	4	12	16	456.654
#395	AFF1	4	14	18	545.739
#396	SOX11	4	10	14	1337.545
#397	MLLT10	4	15	19	508.443
#398	HIF3A	4	9	13	549.038
#399	TSHZ3	4	13	17	2322.007
#400	ZNF174	4	14	18	500.549
#401	NFE2	4	19	23	886.488
#402	EGR3	4	14	18	904.472
#403	RUNX2	4	13	17	506.768
#404	TFDP1	4	16	20	1468.164
#405	NFATC4	4	11	15	223.345
#406	GATAD2B	4	15	19	884.357
#407	HOPX	4	16	20	600.526
#408	HMGA2	4	3	7	117.672
#409	HES6	4	14	18	2273.218
#410	SCMH1	4	13	17	811.833
#411	DRAP1	4	13	17	965.136
#412	HOXA9	4	2	6	65.018
#413	SOX12	4	12	16	1358.739
#414	POU4F1	4	14	18	1016.035
#415	MNT	4	13	17	830.253
#416	CREB5	4	7	11	3209.75
#417	HOXB2	4	9	13	1103.376
#418	ZSCAN2	3	10	13	273.516
#419	HOXA3	3	4	7	535.978
#420	SMAD5	3	12	15	1921.349
#421	NFATC1	3	9	12	1535.883
#422	CEBPA	3	11	14	1932.347
#423	CBFA2T2	3	15	18	497.306
#424	TSC22D1	3	18	21	1157.063
#425	ZNF93	3	9	12	405.135
#426	HESX1	3	8	11	1095.072
#427	ZNF135	3	9	12	1373.118
#428	FOXO6	3	7	10	529.688
#429	NFATC3	3	12	15	726.35
#430	MECOM	3	10	13	667.915
#431	BATF	3	13	16	1513.717
#432	IRX1	3	16	19	770.961
#433	ZNF165	3	14	17	1895.247
#434	MTA1	3	16	19	770.33
#435	KLF5	3	18	21	2288.824
#436	KDM5A	3	13	16	568.632
#437	ZNF396	3	11	14	1415.393
#438	RCAN1	3	15	18	2240.921
#439	NFIA	3	15	18	1228.897
#440	MYNN	3	14	17	1696.341
#441	EGR2	3	10	13	572.507
#442	TULP4	3	11	14	258.903
#443	WT1	3	13	16	824.279
#444	ZHX1	3	16	19	372.768
#445	SP1	3	9	12	233.781
#446	SUPT4H1	3	7	10	900.378
#447	ZNF268	3	16	19	2022.912
#448	IRX2	3	10	13	260.108
#449	PEG3	3	14	17	1202.248
#450	PLAG1	3	8	11	107.335
#451	HOXB3	3	11	14	224.711
#452	ZNF323	3	12	15	186.609
#453	ZFP37	3	12	15	863.623
#454	TCF19	3	12	15	1640.241
#455	ZNF643	3	14	17	457.293
#456	CTBP1	2	7	9	210.425
#457	ARNTL2	2	12	14	617.347
#458	RARA	2	13	15	352.889
#459	GLI3	2	9	11	258.988
#460	NFX1	2	16	18	1485.633
#461	TSC22D4	2	17	19	253.678
#462	ARNTL	2	13	15	221.01
#463	ZFP36L1	2	12	14	1036.907
#464	ZSCAN4	2	11	13	290.685
#465	SMAD3	2	14	16	770.868
#466	NR2F6	2	9	11	219.051
#467	LASS6	2	13	15	648.955
#468	ZSCAN29	2	8	10	291.016
#469	BATF3	2	14	16	421.181
#470	SLC2A4RG	2	16	18	769.106
#471	E2F5	2	11	13	271.445
#472	MYC	2	14	16	1440.538
#473	MSX1	2	12	14	644.905
#474	CUX2	2	11	13	552.792
#475	MITF	2	10	12	535.227
#476	GATA2	2	11	13	423.295
#477	YY1	2	10	12	187.474
#478	HMBOX1	2	15	17	353.589
#479	FOSL1	2	9	11	385.513
#480	STAT1	2	16	18	933.478
#481	ZBTB38	1	17	18	887.044
#482	MEIS1	1	7	8	1455.625
#483	BCL6	1	15	16	113.732
#484	STAT6	1	13	14	186.061
#485	GAS7	1	17	18	107.245
#486	ZNF33B	1	11	12	63.004
#487	PPARA	1	11	12	73.065
#488	STAT5B	1	12	13	303.513
#489	MAFB	1	17	18	853.584
#490	ATF5	1	14	15	376.065
#491	ATF7	1	10	11	103.169
#492	MAFK	1	12	13	248.802
#493	HOXA2	1	14	15	1099.457
#494	MYT1L	1	12	13	459.728
#495	HSF5	1	11	12	186.276
#496	L3MBTL4	1	15	16	196.692
#497	SPEN	0	13	13	0
#498	IRF5	0	10	10	0
#499	NFYA	0	14	14	0
#500	RUNX1	0	15	15	0