Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GABPA	50	2	52	1577.89
#2	TAF4	39	2	41	580.992
#3	ZEB1	38	2	40	5140.166
#4	CDX2	33	5	38	1567.26
#5	PURA	33	6	39	524.429
#6	NFIB	32	7	39	445.196
#7	PLAGL2	31	5	36	2563.779
#8	SATB2	31	11	42	1855.365
#9	SCAND1	29	5	34	867.823
#10	C11orf9	29	11	40	976.906
#11	TSHZ3	28	7	35	1581.635
#12	STRN3	27	3	30	253.905
#13	ZNF24	27	9	36	4604.98
#14	KLF3	27	5	32	2793.909
#15	USF1	26	7	33	2070.452
#16	MEIS1	26	5	31	412.286
#17	TCF7	25	4	29	1975.604
#18	STAT3	25	11	36	1659.969
#19	IRF1	25	11	36	2760.326
#20	GABPB1	25	8	33	2026.929
#21	BCL6	25	10	35	2145.681
#22	TCF4	25	4	29	692.925
#23	ADNP	24	7	31	432.447
#24	SOX4	24	12	36	1781.955
#25	ZEB2	24	5	29	453.801
#26	TRPS1	24	11	35	4283.855
#27	PRRX1	24	2	26	225.6
#28	ELF2	24	9	33	818.477
#29	MTA2	24	3	27	445.881
#30	TGIF2	24	2	26	159.526
#31	TFEC	24	4	28	332.674
#32	GTF2IRD1	24	11	35	1631.458
#33	OVOL1	24	10	34	1916.426
#34	AHCTF1	23	0	23	0
#35	HSF2	23	5	28	207.352
#36	NFAT5	23	7	30	616.963
#37	GLI3	23	2	25	77.421
#38	ZGPAT	22	4	26	2412.341
#39	E2F7	22	9	31	1967.314
#40	IKZF1	21	2	23	91.752
#41	TAF5	21	6	27	1652.76
#42	FLI1	21	4	25	456.353
#43	CUX1	21	13	34	1348.365
#44	PBX1	21	16	37	4914.309
#45	JUND	21	6	27	1973.912
#46	SMAD4	21	6	27	374.43
#47	GTF2I	21	3	24	60.111
#48	ZNF277	21	8	29	1494.133
#49	ZNF148	21	11	32	2437.439
#50	FOSL2	21	7	28	1455.42
#51	ZNF217	21	7	28	675.488
#52	CEBPA	20	8	28	713.177
#53	NR3C1	20	2	22	103.13
#54	ZNF165	20	9	29	1356.045
#55	GTF2H4	20	14	34	2218.717
#56	CITED2	20	8	28	1364.403
#57	SMAD2	20	9	29	932.414
#58	HCLS1	20	5	25	636.964
#59	TFCP2L1	20	15	35	2866.887
#60	FOXN3	19	13	32	3044.786
#61	MITF	19	9	28	382.201
#62	ARNTL2	19	11	30	2139.42
#63	RFX1	19	7	26	2854.45
#64	RUNX1T1	19	8	27	2310.427
#65	MXD1	18	9	27	1131.333
#66	ETS1	18	8	26	1056.003
#67	SNAI2	18	9	27	576.984
#68	UHRF1	18	13	31	3553.455
#69	AEBP1	18	4	22	1119.034
#70	STAT1	18	6	24	719.679
#71	KDM5B	18	10	28	2911.037
#72	TCEAL1	18	11	29	2348.121
#73	ZFPM2	18	7	25	203.223
#74	RUNX1	17	8	25	1186.03
#75	ZFHX3	17	16	33	3737.607
#76	CBFA2T2	17	6	23	1298.877
#77	TFEB	17	10	27	676.573
#78	FOXK2	17	6	23	771.033
#79	NFATC1	17	10	27	1474.015
#80	HIC1	17	8	25	784.777
#81	TCFL5	17	8	25	997.584
#82	ASCL2	17	15	32	1837.972
#83	HIF1A	17	10	27	905.076
#84	FOXF1	17	5	22	177.516
#85	AHR	17	4	21	186.796
#86	PA2G4	16	6	22	1328.16
#87	ZXDA	16	6	22	1307.436
#88	ZNF41	16	4	20	823.527
#89	LEF1	16	14	30	6342.834
#90	ISX	16	16	32	3494.214
#91	ETS2	16	13	29	2431.049
#92	ZBTB38	16	12	28	3562.881
#93	CSRNP1	16	7	23	770.797
#94	ATF1	16	9	25	1043.247
#95	ZNF397	16	8	24	2814.431
#96	NR1I2	16	17	33	2567.174
#97	ZNF93	16	8	24	1773.157
#98	TFAM	16	13	29	3680.074
#99	MAFB	16	6	22	2165.059
#100	ZKSCAN1	15	11	26	1148.611
#101	ZFP36L2	15	11	26	1878.862
#102	ENO1	15	13	28	1021.716
#103	MLL	15	12	27	1546.066
#104	GATAD1	15	6	21	558.701
#105	GLIS2	15	9	24	2415.102
#106	HHEX	15	7	22	1479.739
#107	CCRN4L	15	13	28	3348.185
#108	SMAD1	15	7	22	1027.736
#109	TAF13	15	10	25	3140.169
#110	TAF5L	15	9	24	1779.882
#111	PEG3	15	2	17	58.331
#112	LMO4	15	14	29	1669.257
#113	UBN1	15	8	23	617.016
#114	TFDP2	15	10	25	1616.775
#115	C2orf3	14	8	22	1609.794
#116	BCL3	14	11	25	1756.389
#117	CEBPB	14	9	23	1073.031
#118	TCF15	14	8	22	2031.636
#119	TWIST2	14	7	21	138.384
#120	MEF2C	14	6	20	556.945
#121	ELK3	14	14	28	760.132
#122	ONECUT2	14	7	21	1475.917
#123	FOSL1	14	9	23	2040.855
#124	RUNX3	14	11	25	1346.739
#125	MEOX2	14	6	20	343.382
#126	ETV5	14	9	23	856.378
#127	MAF	14	7	21	223.635
#128	RCOR1	14	12	26	635.501
#129	HOXB5	14	5	19	1038.244
#130	ETV6	14	7	21	254.637
#131	ZNF92	14	9	23	820.146
#132	ZNF281	14	4	18	381.519
#133	BHLHE40	13	10	23	745.369
#134	SPEN	13	5	18	677.738
#135	PURB	13	8	21	359.647
#136	HSF1	13	14	27	1744.785
#137	ZNF263	13	10	23	1377.769
#138	HOXB2	13	14	27	7023.474
#139	ATF7	13	9	22	1701.342
#140	ETV1	13	12	25	2005.04
#141	CREM	13	9	22	568.877
#142	MAX	13	9	22	754.686
#143	HNF4G	13	9	22	615.009
#144	ELF3	13	11	24	2002.792
#145	AFF4	13	3	16	44.15
#146	MEIS2	13	11	24	3906.814
#147	YEATS4	13	11	24	1005.937
#148	STAT2	13	8	21	1048.628
#149	SOX15	13	3	16	448.491
#150	RUNX2	13	11	24	660.908
#151	MYBL2	13	8	21	1143.252
#152	STAT4	12	5	17	429.349
#153	ZNF367	12	3	15	983.021
#154	E2F6	12	11	23	2053.488
#155	VAV1	12	4	16	400.07
#156	SMAD5	12	13	25	1306.621
#157	IRF9	12	7	19	1054.875
#158	ZNF140	12	10	22	1550.598
#159	MLX	12	14	26	2026.395
#160	RB1	12	6	18	2053.64
#161	NR2F1	12	10	22	1644.29
#162	TEAD4	12	6	18	829.6
#163	MECOM	12	14	26	2423.549
#164	ZHX2	12	12	24	1791.791
#165	PHF5A	12	19	31	1994.709
#166	HOXD11	12	6	18	1133.431
#167	RARA	12	7	19	724.145
#168	NFIA	12	14	26	1963.562
#169	JUNB	12	9	21	783.951
#170	ZNF232	12	16	28	1700.643
#171	TAF7	12	10	22	1844.329
#172	E2F8	12	8	20	1257.755
#173	BACH1	12	3	15	17.154
#174	HDAC2	12	13	25	1856.599
#175	MNX1	12	9	21	725.621
#176	ARNT	12	11	23	1504.289
#177	HOXA3	11	17	28	3160.89
#178	SMAD3	11	14	25	1964.905
#179	BATF	11	8	19	1567.498
#180	KLF12	11	15	26	3175.017
#181	NKX3-2	11	8	19	370.688
#182	WNT5A	11	9	20	2378.417
#183	PRDM1	11	15	26	893.306
#184	GTF2H3	11	14	25	1480.623
#185	FOXD2	11	11	22	1476.26
#186	EPAS1	11	12	23	1016.418
#187	SNAPC5	11	7	18	1514.716
#188	ZNF268	11	9	20	1828.488
#189	ETV4	11	10	21	620.817
#190	TFAP2A	11	13	24	2040.406
#191	NFYB	11	14	25	1277.676
#192	ZNF45	11	8	19	1340.097
#193	NR4A1	11	11	22	1113.845
#194	LASS6	11	10	21	1038.683
#195	TULP4	11	9	20	267.493
#196	TCF7L2	11	14	25	2290.038
#197	TRIM28	11	7	18	618.712
#198	CNOT8	11	8	19	1368.825
#199	SATB1	11	17	28	4191.484
#200	TEAD1	11	11	22	910.908
#201	SPDEF	11	13	24	2232.305
#202	RERE	11	12	23	1237.442
#203	GATA6	11	13	24	1236.36
#204	FOXO1	11	15	26	2180.588
#205	MSRB2	11	12	23	1827.994
#206	ZFP37	11	8	19	1177.059
#207	TWIST1	10	11	21	1602.484
#208	KLF10	10	10	20	883.642
#209	ATF6	10	11	21	1745.726
#210	FOXP4	10	11	21	1031.261
#211	SOX11	10	11	21	572.353
#212	SCML2	10	7	17	938.454
#213	ELF4	10	9	19	1542.939
#214	MYCL1	10	9	19	507.654
#215	THRB	10	12	22	1714.551
#216	HOXD10	10	6	16	527.935
#217	NOLC1	10	18	28	1894.161
#218	HOXB8	10	6	16	1457.184
#219	HMGA2	10	18	28	2149.3
#220	HEY2	10	8	18	845.544
#221	TFDP1	10	8	18	1887.504
#222	KLF7	10	14	24	1276.885
#223	ESR1	10	10	20	1623.285
#224	MYC	10	13	23	1492.069
#225	IRF8	10	10	20	2009.941
#226	EOMES	10	10	20	1882.557
#227	MYNN	10	10	20	536.714
#228	TCF12	10	13	23	1956.065
#229	FOXO3	10	11	21	863.885
#230	FOSB	10	8	18	834.44
#231	BATF2	10	8	18	2199.72
#232	MKX	10	12	22	3372.537
#233	ZFP90	10	7	17	585.744
#234	KDM5A	10	14	24	791.883
#235	NR1D2	9	15	24	425.201
#236	ARNTL	9	12	21	952.152
#237	HNF4A	9	12	21	1668.586
#238	CEBPD	9	14	23	1409.539
#239	HEYL	9	10	19	572.968
#240	TP53	9	15	24	2437.32
#241	IRF2	9	8	17	1047.536
#242	KCNH8	9	13	22	1334.905
#243	ZNF75D	9	8	17	705.97
#244	HOXA1	9	15	24	1352.072
#245	ZNF83	9	16	25	3110.758
#246	YY1	9	8	17	1614.729
#247	NKX2-3	9	10	19	457.176
#248	TFE3	9	18	27	2672.982
#249	DLX6	9	6	15	739.184
#250	TAF12	9	9	18	711.195
#251	ARID3A	9	8	17	863.513
#252	SOX6	9	10	19	1755.661
#253	AATF	9	12	21	2200.455
#254	HMG20B	9	8	17	1633.1
#255	TCF3	9	8	17	590.609
#256	SREBF1	9	13	22	556.404
#257	HOXD1	9	11	20	1519.789
#258	PROX1	8	12	20	689.699
#259	C1orf85	8	12	20	2010.975
#260	NR4A3	8	9	17	2056.658
#261	FOXM1	8	13	21	1542.255
#262	EBF1	8	8	16	429.858
#263	HOXA11	8	8	16	1068.553
#264	ZC3H8	8	7	15	529.587
#265	FOXA3	8	13	21	1761.258
#266	ZHX1	8	8	16	1117.64
#267	TSC22D2	8	11	19	482.206
#268	CSRNP3	8	7	15	571.818
#269	KLF4	8	16	24	1951.841
#270	ZNF167	8	9	17	1028.81
#271	ATF4	8	13	21	1774.331
#272	CREB3L2	8	14	22	3184.606
#273	HOXA10	8	5	13	367.857
#274	SOX7	8	14	22	1832.237
#275	HLF	8	11	19	1413.48
#276	PITX1	8	6	14	610.961
#277	SOX9	8	15	23	3152.216
#278	SOX1	8	9	17	1355.979
#279	C5orf41	8	12	20	1369.92
#280	HOXB3	8	9	17	977.238
#281	NR1H4	8	9	17	882.631
#282	SIM2	8	12	20	4008.73
#283	ZNF3	8	8	16	742.563
#284	ZNF33B	8	16	24	1643.858
#285	SOLH	8	11	19	1129.875
#286	ESRRA	8	15	23	1123.79
#287	ZNF274	8	10	18	2640.218
#288	TRERF1	8	12	20	668.449
#289	FOXD1	8	12	20	488.461
#290	GCFC1	8	11	19	772.646
#291	KLF2	7	14	21	1048.414
#292	HOXB6	7	11	18	785.079
#293	TRIM22	7	9	16	1147.935
#294	IRX3	7	12	19	4419.59
#295	EHF	7	8	15	772.124
#296	JUN	7	14	21	1083.478
#297	FOXA1	7	14	21	1593.287
#298	EGR3	7	12	19	1497.784
#299	HOXA5	7	7	14	1160.979
#300	ATF3	7	9	16	1464.145
#301	SOX8	7	11	18	1987.235
#302	MSX1	7	11	18	800.555
#303	E2F5	7	12	19	896.732
#304	KLF6	7	17	24	1127.837
#305	HOXD8	7	16	23	1764.314
#306	TSC22D1	7	14	21	1208.257
#307	PTTG1	7	10	17	1010.437
#308	RFXAP	7	19	26	1969.964
#309	CLOCK	7	12	19	934.776
#310	ARX	7	5	12	723.201
#311	NFATC2	7	14	21	1128.452
#312	ETV7	7	6	13	349.458
#313	NFIL3	7	11	18	1333.815
#314	JDP2	7	12	19	2784.457
#315	ELF1	7	13	20	1067.89
#316	NR5A2	7	11	18	1236.123
#317	CITED1	7	13	20	1349.165
#318	SALL1	7	7	14	1146.665
#319	MBD1	7	15	22	1341.695
#320	MAFK	7	10	17	673.955
#321	MTA1	7	9	16	815.926
#322	GATAD2A	7	15	22	1139.012
#323	TAF10	7	12	19	805.035
#324	NFIC	7	10	17	1632.373
#325	FBXW7	7	16	23	1571.255
#326	ZNF131	7	8	15	1647.058
#327	RBPJ	7	9	16	890.592
#328	ELK4	7	12	19	906.417
#329	BUD31	7	10	17	1202.341
#330	ZNF189	7	13	20	1476.682
#331	TAF4B	7	12	19	1356.362
#332	TAF1B	7	10	17	2924.563
#333	NPAS2	7	12	19	1497.835
#334	PHTF1	7	10	17	658.922
#335	FOXJ3	7	6	13	65.368
#336	NFYA	6	6	12	268.724
#337	CREB3L4	6	12	18	718.515
#338	TRIM25	6	13	19	742.249
#339	ZNF207	6	11	17	390.194
#340	TGIF1	6	9	15	1177.831
#341	ARNT2	6	15	21	1463.913
#342	NFXL1	6	10	16	752.997
#343	HOXD9	6	9	15	1578.753
#344	MYCN	6	13	19	1717.032
#345	CREBL2	6	10	16	1042.924
#346	ZNF323	6	12	18	1086.964
#347	E2F3	6	15	21	977.875
#348	GLIS3	6	10	16	1232.473
#349	HMGA1	6	13	19	717.486
#350	MMP14	6	15	21	856.607
#351	HES6	6	15	21	1062.147
#352	FOXQ1	6	21	27	1069.579
#353	CNOT7	6	10	16	464.975
#354	HOXA7	6	9	15	719.493
#355	SP1	6	12	18	558.895
#356	SLC2A4RG	6	13	19	958.171
#357	ZNF639	6	14	20	721.432
#358	PLAG1	6	13	19	2449.647
#359	MGA	6	17	23	442.037
#360	PITX2	6	16	22	2259.697
#361	NR2C1	6	11	17	657.615
#362	HOPX	6	16	22	848.364
#363	BLZF1	6	7	13	436.188
#364	NFE2L1	6	17	23	1138.029
#365	CREB3L1	6	20	26	1616.214
#366	SLC26A3	6	21	27	948.407
#367	NFE2L3	6	16	22	790.74
#368	BHLHE41	6	15	21	552.135
#369	GATA3	6	8	14	861.876
#370	RXRA	6	11	17	1225.031
#371	ZNF256	6	13	19	1122.152
#372	TSHZ2	6	15	21	688.838
#373	TARDBP	6	13	19	1038.086
#374	WT1	6	19	25	2219.725
#375	NKX3-1	6	15	21	1216.078
#376	ZNF138	6	8	14	394.259
#377	HEY1	6	12	18	416.455
#378	HOXB9	6	8	14	723.11
#379	HMGB1	6	10	16	1087.925
#380	LCOR	5	13	18	638.456
#381	HR	5	12	17	1359.726
#382	CREB5	5	8	13	1308.648
#383	RORC	5	13	18	976.401
#384	ISL1	5	12	17	424.377
#385	NFE2L2	5	5	10	285.033
#386	PPARA	5	13	18	620.045
#387	MESP1	5	15	20	1653.184
#388	ZSCAN16	5	11	16	768.499
#389	GRHL2	5	12	17	430.597
#390	ATOH1	5	12	17	640.355
#391	FOXK1	5	13	18	1368.146
#392	TCF25	5	11	16	895.251
#393	FUBP1	5	10	15	869.316
#394	NEUROD1	5	5	10	279.644
#395	EGR2	5	11	16	805.893
#396	BCL11B	5	12	17	658.002
#397	ST18	5	5	10	420.35
#398	TFAP2C	5	19	24	1328.32
#399	GTF2H2	5	16	21	1398.321
#400	BTG2	5	17	22	811.451
#401	HES1	5	19	24	1608.444
#402	FOXP1	5	17	22	1518.831
#403	NOTCH1	5	8	13	433.119
#404	IRF7	5	10	15	720.777
#405	ZNF238	5	10	15	3588.866
#406	FOXF2	5	7	12	463.47
#407	KLF11	5	8	13	1362.925
#408	SREBF2	5	14	19	1158.904
#409	ZSCAN18	5	14	19	805.184
#410	TSC22D3	5	11	16	1699.331
#411	GAS7	5	12	17	235.669
#412	RBCK1	5	13	18	2818.159
#413	SP4	5	6	11	497.966
#414	TCF21	5	9	14	375.392
#415	HOXD13	5	10	15	991.265
#416	MLLT10	5	9	14	604.107
#417	FOXC1	5	15	20	886.522
#418	FOXA2	5	14	19	1946.999
#419	PHF1	5	13	18	755.954
#420	DMRT2	5	15	20	1656.896
#421	HOXB7	5	6	11	343.685
#422	SOX12	5	9	14	1032.784
#423	MSX2	5	17	22	1234.918
#424	CTNNB1	5	11	16	610.073
#425	TFCP2	5	6	11	605.546
#426	ZNF134	5	9	14	759.983
#427	NR2F2	5	14	19	1356.478
#428	L3MBTL4	5	14	19	732.526
#429	NFIX	5	14	19	425.252
#430	HMBOX1	4	11	15	446.25
#431	HIRA	4	9	13	785.592
#432	CBFB	4	10	14	711.355
#433	SLC30A9	4	19	23	964.601
#434	TBX3	4	10	14	768.44
#435	CREBZF	4	18	22	857.36
#436	IRF6	4	11	15	436.235
#437	SUPT4H1	4	16	20	1051.046
#438	PLSCR1	4	13	17	675.39
#439	IRF4	4	10	14	678.704
#440	KLF9	4	18	22	752.399
#441	FOS	4	16	20	1425.619
#442	HMX2	4	4	8	100.765
#443	SOX2	4	10	14	514.864
#444	SMAD6	4	13	17	444.275
#445	PCGF2	4	11	15	663.664
#446	RFX5	4	8	12	1035.304
#447	RORA	4	13	17	264.531
#448	BARX1	4	9	13	879.732
#449	MEIS3P1	4	8	12	582.621
#450	ARID4A	4	12	16	586.828
#451	FOXP2	4	20	24	2165.162
#452	NFATC3	4	15	19	916.618
#453	IRX2	4	11	15	1190.755
#454	ELF5	4	16	20	782.049
#455	EGR1	4	12	16	1502.653
#456	ZNF85	4	9	13	352.21
#457	PBX3	4	13	17	1085.957
#458	HMGB2	4	12	16	477.774
#459	SOX30	4	6	10	405.976
#460	RCAN1	4	13	17	178.003
#461	SCML1	3	9	12	718.344
#462	ZIC2	3	17	20	304.395
#463	SMAD9	3	15	18	379.941
#464	TEAD2	3	10	13	1239.925
#465	HOXA13	3	12	15	461.745
#466	HOXA2	3	14	17	525.414
#467	CDKN2A	3	10	13	278.276
#468	NR1H3	3	14	17	456.951
#469	ZNF91	3	15	18	641.623
#470	HOXA9	3	10	13	554.021
#471	XBP1	3	16	19	618.552
#472	IRF5	3	8	11	356.143
#473	HDAC1	3	10	13	654.869
#474	PPARG	3	15	18	372.248
#475	GRHL3	3	14	17	544.523
#476	VDR	2	20	22	1362.948
#477	ESRRG	2	10	12	282.044
#478	SIN3A	2	11	13	362.588
#479	ZFP36L1	2	16	18	382.946
#480	MAFF	2	19	21	258.679
#481	TRIM29	2	12	14	1407.691
#482	FOXG1	2	10	12	743.275
#483	NCOR1	2	13	15	117.907
#484	TSHZ1	2	13	15	545.747
#485	SIX1	2	13	15	185.727
#486	DDIT3	2	13	15	630.687
#487	CREBBP	1	12	13	356.442
#488	NFX1	1	12	13	107.538
#489	NR4A2	1	17	18	234.274
#490	KLF5	1	13	14	134.799
#491	HOXB13	1	15	16	950.605
#492	NR3C2	1	14	15	500.685
#493	ZRANB2	1	10	11	508.978
#494	PAX6	1	9	10	399.045
#495	ZNF643	1	12	13	386.864
#496	CTBP1	1	14	15	210.269
#497	SCAND3	0	16	16	0
#498	EN2	0	10	10	0
#499	ZNF117	0	15	15	0
#500	TCF19	0	11	11	0