Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	YY1	65	2	67	6679.661
#2	MEIS2	58	3	61	503.033
#3	TBX19	53	3	56	5814.52
#4	CREB3L4	52	0	52	0
#5	ZEB2	52	8	60	1053.525
#6	NFATC4	51	4	55	3642.702
#7	TWIST2	45	7	52	734.073
#8	FOXF1	43	8	51	3334.18
#9	SP1	42	4	46	294.083
#10	GLIS2	42	4	46	962.761
#11	HOXB13	41	5	46	1025.56
#12	RORC	41	8	49	664.791
#13	PGR	40	1	41	294.999
#14	SPDEF	40	2	42	74.895
#15	TCF7L1	39	9	48	765.089
#16	NR4A1	38	0	38	0
#17	TEAD3	38	2	40	44.959
#18	NKX3-1	38	3	41	617.112
#19	MZF1	37	4	41	315.81
#20	MESP1	37	6	43	1263.174
#21	EPAS1	36	6	42	393.32
#22	ELF4	35	6	41	5388.622
#23	PEG3	35	7	42	130.179
#24	YBX1	34	2	36	534.224
#25	SLC30A9	34	13	47	3613.372
#26	HOXD10	34	6	40	115.34
#27	SIM2	34	16	50	2432.518
#28	ZKSCAN1	33	8	41	707.334
#29	FBXW7	33	3	36	99.487
#30	TFAM	32	8	40	1285.059
#31	SOX15	31	7	38	4648.246
#32	HLF	31	7	38	1232.802
#33	CBL	31	8	39	1111.518
#34	RBCK1	30	2	32	33.953
#35	ZSCAN18	30	10	40	8241.19
#36	ELK4	30	6	36	1121.883
#37	TSHZ3	30	3	33	52.017
#38	L3MBTL4	29	9	38	364.384
#39	GATA3	29	11	40	2443.04
#40	HIF3A	29	10	39	1321.918
#41	POU6F1	29	7	36	1235.42
#42	CEBPB	29	7	36	5604.314
#43	JUND	29	8	37	911.218
#44	ZEB1	29	4	33	351.39
#45	HIC1	29	1	30	131.939
#46	JUNB	28	4	32	88.798
#47	GRHL2	28	8	36	673.43
#48	CSRNP1	28	3	31	839.584
#49	STAT4	27	11	38	2169.437
#50	KLF6	27	10	37	8046.24
#51	TFAP2C	27	13	40	3855.914
#52	EHF	27	13	40	4599.405
#53	GAS7	27	9	36	395.404
#54	ENO1	27	7	34	166.788
#55	MSRB2	27	13	40	2105.812
#56	GABPB1	27	4	31	17027.11
#57	ZBTB38	26	6	32	195.723
#58	FOXC2	26	10	36	11637.877
#59	EGR1	26	6	32	910.696
#60	FOXP4	26	7	33	155.687
#61	EDF1	26	6	32	977.949
#62	LMO4	26	11	37	5088.781
#63	HOXD11	26	3	29	559.875
#64	POU2F1	26	4	30	1544.635
#65	GATA5	25	8	33	152.448
#66	ERG	25	13	38	17641.204
#67	FOSB	25	3	28	194.62
#68	ATF6B	25	10	35	2811.41
#69	MGA	25	9	34	730.08
#70	SOX10	24	4	28	582.641
#71	ZBTB17	24	3	27	416.285
#72	ZNF148	24	10	34	1035.92
#73	TEAD1	23	11	34	2130.126
#74	TCF7L2	23	5	28	764.11
#75	SCAND3	23	12	35	419.421
#76	PBX1	23	3	26	446.679
#77	CEBPD	23	9	32	404.202
#78	CREM	23	7	30	915.698
#79	MEIS1	23	13	36	1015.397
#80	C1orf85	23	10	33	363.523
#81	ZNF434	23	10	33	1670.811
#82	REL	23	9	32	641.034
#83	ZSCAN16	23	15	38	3539.156
#84	CSDA	22	16	38	11580.53
#85	FOS	22	2	24	10.052
#86	RERE	22	5	27	261.434
#87	NFX1	22	9	31	10572.065
#88	TAL1	22	11	33	1531.47
#89	GATA6	22	12	34	5302.432
#90	MITF	22	8	30	1558.398
#91	FOXO1	22	15	37	2663.212
#92	TSC22D1	22	14	36	816.003
#93	FOSL2	22	7	29	1014.754
#94	SATB2	21	14	35	819.691
#95	HCLS1	21	5	26	617.362
#96	HOXB8	21	12	33	3597.747
#97	TBX2	21	11	32	547.706
#98	ZNF213	21	12	33	4047.645
#99	E2F3	21	13	34	1492.204
#100	SMAD3	21	7	28	8206.297
#101	GLI3	21	8	29	1462.378
#102	FOXA1	21	9	30	921.609
#103	RUNX1T1	21	7	28	795.371
#104	MTA3	21	12	33	3115.946
#105	NOLC1	21	12	33	1678.887
#106	TBX5	20	9	29	2418.61
#107	MAFF	20	5	25	117.132
#108	BATF3	20	15	35	2176.272
#109	ETS1	20	13	33	4038.594
#110	DLX1	19	10	29	1410.438
#111	GBX2	19	3	22	867.219
#112	MLLT10	19	15	34	600.681
#113	NR4A3	19	8	27	368.751
#114	EGR3	19	6	25	1680.397
#115	NR4A2	19	8	27	2397.649
#116	ATF3	19	8	27	4661.628
#117	DRAP1	19	12	31	13383.427
#118	IRX2	19	18	37	2308.071
#119	ARNTL2	19	15	34	3011.042
#120	SMAD6	19	11	30	839.064
#121	TRIM29	19	11	30	1397.467
#122	FOXP2	19	12	31	865.141
#123	HNF1B	19	19	38	5915.285
#124	BCL3	18	5	23	887.429
#125	MEOX2	18	11	29	1463.384
#126	KLF10	18	11	29	2557.912
#127	CUX2	18	9	27	144.041
#128	HOXA9	18	12	30	11941.075
#129	KLF9	18	13	31	2902.145
#130	AEBP1	18	11	29	2333.797
#131	EGR2	18	7	25	1095.153
#132	NFIB	18	9	27	678.392
#133	BHLHE40	18	11	29	999.158
#134	HOXB2	18	16	34	3756.111
#135	TULP4	18	13	31	2493.265
#136	ZFPM2	18	11	29	651.52
#137	KLF7	18	12	30	666.073
#138	PTTG1	18	10	28	1867.005
#139	SMAD5	18	10	28	928.427
#140	TFCP2	18	13	31	543.71
#141	TFEB	18	14	32	4873.696
#142	SP140	18	3	21	89.643
#143	SNAI2	18	12	30	432.665
#144	BCL6	18	7	25	4356.057
#145	CREB3	17	11	28	2072.838
#146	ZNF91	17	14	31	1160.781
#147	ONECUT2	17	10	27	255.516
#148	POU3F4	17	3	20	42.962
#149	E2F5	17	9	26	1930.534
#150	GLIS3	17	13	30	548.286
#151	RCAN1	17	11	28	818.552
#152	FOSL1	17	9	26	1018.521
#153	CSRNP3	17	7	24	168.115
#154	ZNF277	17	10	27	1427.489
#155	NFE2L2	17	4	21	113.247
#156	CCRN4L	17	13	30	4457.087
#157	HOXA11	17	14	31	1490.041
#158	NFIL3	16	5	21	1530.775
#159	MAF	16	14	30	773.156
#160	ISL1	16	12	28	1741.935
#161	PKNOX2	16	13	29	3389.507
#162	NFIC	16	10	26	1521.256
#163	CEBPA	16	10	26	424.583
#164	SPI1	16	17	33	2551.713
#165	FOXN4	16	8	24	915.342
#166	HNF4G	16	17	33	3789.716
#167	AHR	16	10	26	1533.218
#168	IRF7	15	12	27	1032.532
#169	IRF6	15	16	31	2476.295
#170	MYC	15	14	29	7833.132
#171	SOX2	15	14	29	3498.977
#172	TEAD4	15	12	27	2762.274
#173	DLX2	15	5	20	60.823
#174	HHEX	15	19	34	3049.466
#175	ELF5	15	18	33	681.426
#176	ZIC2	15	11	26	489.899
#177	PLAG1	15	14	29	3279.063
#178	NFIX	15	12	27	711.676
#179	TFDP1	15	13	28	2441.318
#180	SOX4	15	10	25	1505.445
#181	RUNX3	15	6	21	817.466
#182	BCL11B	15	8	23	532.951
#183	ZNF396	15	17	32	1786.039
#184	FOXO3	15	15	30	1377.864
#185	UHRF1	14	10	24	602.202
#186	TCF4	14	10	24	598.376
#187	HOXC4	14	9	23	709.424
#188	NFATC3	14	15	29	4017.075
#189	CREBBP	14	9	23	2224.377
#190	MSX1	14	17	31	726.496
#191	KLF12	14	9	23	635.462
#192	LHX9	14	4	18	47.668
#193	HOXB7	14	14	28	2100.616
#194	MEOX1	14	18	32	3659.196
#195	NKX2-3	14	12	26	426.845
#196	ELK3	14	11	25	1533.863
#197	HOXA7	14	12	26	956.959
#198	CBFA2T3	14	16	30	10475.716
#199	STAT3	14	7	21	67.656
#200	E2F8	13	12	25	3255.887
#201	ZNF174	13	13	26	1102.917
#202	HOXD9	13	9	22	3169.036
#203	FLI1	13	10	23	2089.169
#204	CLOCK	13	11	24	351.105
#205	PRDM2	13	10	23	1145.88
#206	IRF1	13	8	21	1849.684
#207	VDR	13	12	25	3390.055
#208	CREBZF	13	14	27	1623.974
#209	ETV5	13	15	28	375.026
#210	KLF16	13	8	21	1570.906
#211	SLC26A3	13	19	32	5709.474
#212	PURB	13	11	24	2059.822
#213	CUX1	13	12	25	1415.249
#214	EN2	13	15	28	1073.915
#215	HOXA1	13	21	34	3012.251
#216	ATF5	13	17	30	960.352
#217	TRPS1	13	10	23	531.955
#218	TCF21	12	13	25	1375.685
#219	CNOT7	12	9	21	884.134
#220	CREB1	12	11	23	2150.683
#221	ISX	12	22	34	1395.065
#222	HOXB3	12	9	21	488.963
#223	AFF4	12	13	25	676.324
#224	E2F2	12	7	19	384.708
#225	ERF	12	11	23	527.43
#226	FEV	12	17	29	4171.903
#227	TP63	12	13	25	639.371
#228	MEF2C	12	14	26	920.347
#229	ZKSCAN4	12	11	23	283.53
#230	FOXM1	12	17	29	3261.434
#231	MECOM	12	13	25	1912.458
#232	LASS6	12	10	22	447.158
#233	MXD1	12	12	24	1049.309
#234	LHX4	12	7	19	356.282
#235	HOXC10	12	8	20	914.096
#236	AFF1	11	4	15	639.411
#237	ZNF202	11	12	23	967.985
#238	SIX3	11	7	18	2686.94
#239	HOXD13	11	15	26	1351.349
#240	VAV1	11	9	20	1261.743
#241	PBX2	11	15	26	1273.961
#242	ELF3	11	18	29	1914.773
#243	ZNF140	11	13	24	1714.448
#244	MMP14	11	18	29	3200.096
#245	NR2C1	11	11	22	543.299
#246	REST	11	14	25	563.713
#247	ATF6	10	9	19	977.181
#248	NFATC2	10	14	24	1002.205
#249	SIX2	10	15	25	6051.285
#250	FOXL1	10	12	22	830.905
#251	ZNF24	10	15	25	4241.284
#252	C2orf3	10	17	27	966.988
#253	SP3	10	12	22	255.52
#254	KLF4	10	9	19	4993.364
#255	FOXD1	10	15	25	1589.138
#256	BTG2	10	13	23	485.366
#257	SMAD4	10	9	19	1487.044
#258	CREB3L1	10	21	31	1107.614
#259	NPAS2	10	16	26	2966.774
#260	HOXD8	10	8	18	616.713
#261	GLI2	10	14	24	930.59
#262	RFXANK	9	12	21	1420.279
#263	TWIST1	9	18	27	3622.135
#264	PKNOX1	9	16	25	1151.709
#265	NANOG	9	19	28	1702.986
#266	MNT	9	10	19	845.196
#267	IKZF1	9	12	21	875.275
#268	MNX1	9	18	27	1675.896
#269	ZXDC	9	11	20	3685.12
#270	POU2F3	9	14	23	1706.69
#271	EGR4	9	13	22	12868.755
#272	C5orf41	9	13	22	688.386
#273	FOXQ1	9	13	22	466.564
#274	PGBD1	9	15	24	613.261
#275	ZSCAN2	9	17	26	1510.424
#276	NPAT	9	8	17	3260.692
#277	FOXD3	9	15	24	2629.446
#278	TP53	9	13	22	2653.041
#279	NOTCH1	9	17	26	1333.344
#280	ZFP36L1	9	18	27	1111.74
#281	HDX	9	16	25	1012.12
#282	SOX17	9	16	25	719.783
#283	SCAND1	9	15	24	881.585
#284	SOX9	9	19	28	998.432
#285	KLF5	9	12	21	2137.112
#286	MAX	8	12	20	371.326
#287	HOXA2	8	17	25	1028.505
#288	E2F7	8	18	26	3092.172
#289	CREB5	8	11	19	1068.483
#290	HOXD4	8	18	26	3780.218
#291	SOX7	8	15	23	1357.139
#292	ESR1	8	19	27	2770.737
#293	TEF	8	13	21	1012.944
#294	CBFA2T2	8	15	23	662.617
#295	BHLHE41	8	18	26	8675.143
#296	TSC22D4	8	9	17	861.213
#297	TSC22D2	8	13	21	1058.124
#298	KCNH8	8	21	29	1946.632
#299	SPEN	8	12	20	1750.064
#300	ZNF215	8	16	24	1058.238
#301	SIX4	7	14	21	741.53
#302	GTF2H2	7	18	25	1484.694
#303	MYF6	7	14	21	2003.564
#304	TSC22D3	7	15	22	159.657
#305	NKX2-1	7	11	18	151.767
#306	LEF1	7	11	18	1000.417
#307	FOXF2	7	14	21	763.888
#308	IRF4	7	13	20	1967.039
#309	ZNF75D	7	14	21	1120.692
#310	IRX3	7	20	27	2939.196
#311	HOXC9	7	9	16	345.334
#312	ZNF135	7	14	21	350.553
#313	HOXB6	7	12	19	1825.68
#314	EBF1	7	20	27	3139.849
#315	FOXP1	7	13	20	1954.321
#316	SIN3A	7	14	21	3436.888
#317	TFCP2L1	7	25	32	2857.929
#318	MLL	7	15	22	1846.353
#319	RUNX2	7	13	20	2053.709
#320	GRHL3	7	19	26	4251.985
#321	NR2F1	7	13	20	949.49
#322	BACH2	7	15	22	719.888
#323	CREB3L2	7	17	24	1602.894
#324	CITED2	7	11	18	10222.75
#325	ZNF165	7	19	26	1006.866
#326	NR2E1	7	16	23	1149.409
#327	GATA2	7	22	29	1092.65
#328	AR	7	13	20	824.833
#329	YEATS4	7	13	20	438.311
#330	TFEC	7	16	23	2276.394
#331	PLSCR1	7	16	23	1055.514
#332	ETV3	7	15	22	902.239
#333	JUN	6	10	16	100.477
#334	LHX6	6	12	18	304.435
#335	RFX3	6	18	24	362.58
#336	PPARG	6	23	29	4063.783
#337	ZNF207	6	16	22	619.799
#338	TBX4	6	13	19	1670.988
#339	MSX2	6	18	24	654.694
#340	MYCL1	6	20	26	11352.319
#341	MESP2	6	8	14	159.056
#342	ATF7	6	17	23	1669.529
#343	STAT1	6	11	17	452.729
#344	LHX8	6	12	18	1361.919
#345	NFIA	6	11	17	442.167
#346	NFYC	6	13	19	786.01
#347	TRIM25	6	20	26	497.914
#348	FOXD2	6	16	22	2671.179
#349	KLF3	6	16	22	1305.335
#350	RXRG	6	17	23	1014.98
#351	ZNF167	6	14	20	265.201
#352	ZSCAN12	6	17	23	349.295
#353	PAX3	6	9	15	1022.296
#354	FUBP1	6	18	24	1092.265
#355	HMGA1	6	17	23	899.802
#356	HESX1	6	18	24	851.66
#357	SCAND2	5	19	24	584.041
#358	ZNF33A	5	17	22	372.228
#359	PPARD	5	16	21	654.745
#360	HOXB5	5	10	15	830.005
#361	HOXA5	5	18	23	437.287
#362	TRERF1	5	13	18	680.94
#363	ZIC3	5	14	19	1129.143
#364	SIX1	5	16	21	693.228
#365	PITX2	5	13	18	163.453
#366	BATF2	5	18	23	1241.227
#367	ESRRG	5	19	24	339.571
#368	NFE2L3	5	22	27	1266.468
#369	TFAP2A	5	13	18	293.851
#370	TAF4B	5	18	23	1685.713
#371	ZNF117	5	23	28	1272.828
#372	ETV7	5	14	19	583.106
#373	ZNF197	5	14	19	154.564
#374	ASCL2	5	19	24	2581.352
#375	HOXD3	5	19	24	2391.23
#376	STAT2	5	14	19	504.868
#377	ZNF93	5	17	22	508.098
#378	STAT6	5	13	18	900.056
#379	FOXC1	5	16	21	846.529
#380	TCF12	5	11	16	1038.375
#381	FOXH1	5	16	21	382.384
#382	HEY1	5	16	21	1023.699
#383	ZFP37	5	18	23	833.604
#384	OVOL1	5	23	28	6388.267
#385	SLC2A4RG	5	19	24	791.494
#386	ASCL1	5	17	22	1683.021
#387	CTNNB1	5	12	17	796.092
#388	ZHX2	5	13	18	708.14
#389	IKZF4	5	15	20	714.562
#390	ETS2	4	18	22	706.628
#391	HOXA4	4	16	20	672.998
#392	IRX5	4	22	26	2613.027
#393	PRDM1	4	11	15	154.727
#394	NFYA	4	16	20	593.213
#395	TCF25	4	17	21	14881.924
#396	NKX3-2	4	18	22	326.292
#397	ETV2	4	18	22	186.859
#398	MKX	4	13	17	363.349
#399	ZSCAN23	4	14	18	713.837
#400	HEYL	4	28	32	2823.173
#401	ZFHX4	4	19	23	4810.447
#402	RUNX1	4	19	23	2656.278
#403	HSF5	4	17	21	2510.003
#404	RORB	4	20	24	860.412
#405	TEAD2	4	19	23	213.255
#406	THRA	4	13	17	476.867
#407	FOXA3	4	20	24	2038.801
#408	TSHZ2	4	19	23	1802.93
#409	ELF2	4	21	25	973.114
#410	IRF8	4	13	17	271.371
#411	DLX6	4	17	21	1045.749
#412	ZNF287	4	26	30	670.351
#413	NFAT5	4	10	14	101.089
#414	BNC1	4	15	19	1187.234
#415	ZNF33B	3	22	25	493.852
#416	HOXC11	3	17	20	2093.01
#417	PRRX1	3	19	22	1689.302
#418	NANOGNB	3	15	18	1749.968
#419	ZNF83	3	20	23	1413.894
#420	MYNN	3	19	22	1849.284
#421	HNF4A	3	10	13	1073.222
#422	HMG20B	3	13	16	581.148
#423	SOX6	3	15	18	245.306
#424	NFATC1	3	11	14	748.501
#425	DBP	3	17	20	1284.561
#426	THRB	3	20	23	1233.843
#427	ZNF397	3	11	14	499.771
#428	IRF5	3	17	20	9777.697
#429	TGIF1	3	23	26	1158.126
#430	ZNF81	3	12	15	290.051
#431	TCF19	3	28	31	1638.888
#432	ISL2	3	12	15	1731.945
#433	ETV1	3	23	26	688.011
#434	EOMES	3	12	15	222.211
#435	FOXL2	3	18	21	156.576
#436	WNT5A	3	24	27	1546.128
#437	ZNF85	3	16	19	655.608
#438	ZKSCAN3	3	23	26	660.663
#439	ZFHX3	3	13	16	693.401
#440	ZNF132	2	19	21	206.675
#441	SOX30	2	17	19	3354.614
#442	HOXD1	2	14	16	311.571
#443	ZIC1	2	22	24	2107.836
#444	CDKN2A	2	19	21	183.757
#445	ZNF643	2	21	23	978.313
#446	MYT1	2	20	22	11674.969
#447	HES1	2	20	22	526.174
#448	STRN3	2	16	18	221.303
#449	TBX3	2	18	20	1641.784
#450	KLF15	2	25	27	2659.096
#451	RHOXF1	2	14	16	1668.247
#452	HMBOX1	2	13	15	1667.521
#453	FOXA2	2	19	21	1011.077
#454	HOPX	2	16	18	187.879
#455	HEY2	2	20	22	243.161
#456	FOXG1	2	10	12	40.947
#457	SALL1	2	24	26	1331.734
#458	FOXE1	2	21	23	223.506
#459	ZNF367	2	15	17	92.144
#460	JDP2	2	15	17	75.397
#461	RXRB	2	17	19	787.48
#462	WT1	2	22	24	713.323
#463	CITED1	2	15	17	1611.961
#464	ZNF131	2	20	22	157.83
#465	PROX1	2	17	19	1587.213
#466	FOXI1	2	19	21	244.517
#467	HOXB4	2	18	20	314.63
#468	SOX8	2	22	24	232.552
#469	TBX1	2	17	19	1426.669
#470	ARNTL	2	14	16	266.856
#471	C12orf28	2	14	16	770.815
#472	IRX4	1	17	18	49.011
#473	GCM1	1	18	19	2678.572
#474	NR1D2	1	13	14	74.521
#475	HMX2	1	17	18	37.419
#476	TBX15	1	19	20	346.807
#477	ALX1	1	21	22	752.437
#478	HAND1	1	14	15	65.223
#479	ARX	1	30	31	75.412
#480	TAF1B	1	19	20	45.493
#481	ZNF496	1	14	15	76.174
#482	ZNF193	1	19	20	349.979
#483	HMGA2	1	18	19	269.953
#484	PPARA	1	15	16	554.682
#485	SOX11	1	7	8	11.078
#486	ST18	1	13	14	57.679
#487	RORA	1	24	25	437.636
#488	ZSCAN20	1	18	19	1136.054
#489	ZNF483	1	18	19	166.631
#490	TFDP2	1	20	21	349.318
#491	KLF2	1	15	16	18.865
#492	DMRT2	0	16	16	0
#493	TAF13	0	16	16	0
#494	ETV6	0	22	22	0
#495	NR5A2	0	22	22	0
#496	ZNF80	0	10	10	0
#497	TBX10	0	23	23	0
#498	NR1H4	0	18	18	0
#499	SPIB	0	13	13	0
#500	ZNF238	0	14	14	0