Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	GATA3	79	2	81	166.22
#2	FOXM1	75	5	80	2334.359
#3	FOXA1	74	2	76	70.071
#4	ESR1	69	4	73	1227.668
#5	E2F8	61	5	66	1714.564
#6	FOXC1	61	2	63	804.215
#7	XBP1	54	6	60	1546.821
#8	HNRNPK	52	0	52	0
#9	SOX10	50	3	53	958.292
#10	CTBP1	50	3	53	68.377
#11	PTTG1	48	2	50	107.091
#12	E2F1	46	5	51	626.43
#13	RARA	45	10	55	529.973
#14	EBF1	45	5	50	1763.02
#15	ZNF3	45	1	46	4.051
#16	TCF4	44	2	46	84.881
#17	SPDEF	43	6	49	411.831
#18	SOX11	43	7	50	3269.821
#19	NPAS1	42	11	53	1698.68
#20	NFIL3	42	5	47	633.355
#21	NFIA	41	11	52	3361.821
#22	HDAC2	41	5	46	141.391
#23	AR	40	13	53	2597.028
#24	CSDA	39	16	55	4177.742
#25	TBX19	38	5	43	105.82
#26	NOTCH1	38	7	45	3370.502
#27	USF2	37	7	44	123.212
#28	ZEB2	35	6	41	1100.609
#29	GABPB1	35	9	44	8810.774
#30	GAS7	34	5	39	2984.328
#31	BHLHE40	33	8	41	1674.666
#32	E2F3	33	9	42	366.128
#33	MAX	33	6	39	654.819
#34	CREB3L4	33	13	46	1835.116
#35	CUX1	33	3	36	532.359
#36	ELF5	32	10	42	1543.649
#37	PRRX1	32	0	32	0
#38	LASS6	32	11	43	862.378
#39	AEBP1	32	2	34	1015.506
#40	CDKN2A	32	15	47	1890.404
#41	MYCN	31	9	40	2620.433
#42	TCF19	31	14	45	2932.409
#43	TCF7L1	31	18	49	3515.437
#44	ETS1	31	6	37	532.771
#45	TCEAL1	31	13	44	866.487
#46	GTF2H3	30	6	36	3038.55
#47	PKNOX1	30	5	35	1231.708
#48	TSHZ3	30	5	35	84.451
#49	TSHZ2	30	8	38	2923.783
#50	OTX1	30	17	47	1838.632
#51	TSC22D1	29	11	40	1605.475
#52	FOXN2	29	9	38	1263.324
#53	SP140	29	5	34	301.332
#54	TBX4	29	7	36	4558.682
#55	PGR	29	15	44	474.882
#56	NFIB	29	15	44	1017.855
#57	E2F2	28	6	34	413.107
#58	MYBL2	28	5	33	295.622
#59	CEBPB	28	9	37	680.385
#60	EN1	28	12	40	708.442
#61	DBP	28	16	44	2001.819
#62	HOXA4	28	8	36	977.253
#63	HES6	27	11	38	1112.606
#64	ZIC3	27	6	33	233.031
#65	HEYL	27	3	30	27.585
#66	C5orf41	27	11	38	837.994
#67	POU4F1	26	10	36	3497.654
#68	TCF7L2	26	15	41	1058.889
#69	MSL3	26	9	35	5526.848
#70	UHRF1	26	10	36	1630.815
#71	ZFP36L1	26	12	38	1048.847
#72	SNAI2	26	8	34	1792.446
#73	MEF2C	26	8	34	1573.755
#74	HOXA2	25	7	32	3351.575
#75	TSC22D3	25	6	31	60.373
#76	TFDP1	25	18	43	841.756
#77	HCLS1	25	0	25	0
#78	EPAS1	25	13	38	1374.375
#79	BTG2	25	14	39	2673.102
#80	HMGB2	25	7	32	1384.183
#81	LMO4	25	17	42	867.344
#82	PURA	25	11	36	621.265
#83	RORC	24	15	39	1380.125
#84	ARNTL2	24	4	28	1738.775
#85	KLF5	24	11	35	441.528
#86	RELA	24	11	35	634.248
#87	PGBD1	24	12	36	1323.811
#88	MYC	24	13	37	1427.132
#89	SOX8	24	11	35	1365.842
#90	SCMH1	24	11	35	2306.368
#91	BARX1	24	15	39	5715.842
#92	PCGF2	24	13	37	6177.569
#93	SOX17	24	8	32	1802.676
#94	E2F5	24	14	38	2002.363
#95	ZNF174	24	14	38	1808.646
#96	TBX15	23	9	32	302.215
#97	GLI2	23	10	33	529.351
#98	ZNF91	23	16	39	826.391
#99	E2F7	23	11	34	2159.388
#100	SPI1	23	5	28	1186.821
#101	MNX1	23	21	44	1906.998
#102	GTF2I	23	9	32	281.352
#103	POU2F2	22	6	28	749.415
#104	PRDM1	22	8	30	502.712
#105	TFCP2L1	22	16	38	3856.886
#106	IRF8	22	3	25	301.998
#107	EHF	22	15	37	3312.607
#108	ETV5	22	17	39	898.475
#109	SNAPC2	22	8	30	1201.628
#110	NEUROD2	22	4	26	123.727
#111	RCOR2	22	17	39	1572.37
#112	SPIB	22	14	36	3068.102
#113	ZNF367	22	7	29	732.932
#114	FOXO3	22	17	39	2089.48
#115	ZNF238	22	22	44	3876.304
#116	SIX5	22	21	43	2166.328
#117	GLI3	22	12	34	341.198
#118	HSF1	22	11	33	1062.515
#119	VSX2	21	11	32	1760.848
#120	NME2	21	28	49	2230.885
#121	MSC	21	9	30	199.757
#122	STAT1	21	9	30	683.197
#123	MAF	21	9	30	1584.699
#124	SLC2A4RG	21	14	35	959.596
#125	BATF2	21	10	31	1310.096
#126	ZNF274	21	9	30	223.491
#127	SCAND1	21	9	30	320.105
#128	SLC26A3	21	18	39	2403.795
#129	RORA	20	13	33	2696.728
#130	KCNH8	20	12	32	1377.758
#131	TEAD4	20	10	30	711.203
#132	VENTX	20	12	32	3394.788
#133	SCML2	20	15	35	1145.821
#134	ANKRD30A	20	17	37	857.677
#135	MEOX1	20	10	30	2082.285
#136	MECOM	20	9	29	182.668
#137	KLF10	20	10	30	449.895
#138	HOXC11	20	18	38	1409.846
#139	TADA3	20	7	27	898.349
#140	RUNX3	20	6	26	539.126
#141	TGIF2	20	17	37	1025.696
#142	TGIF1	20	4	24	1759.018
#143	FOXS1	20	8	28	1241.015
#144	MEIS3	20	14	34	490.822
#145	GABPA	20	9	29	934.31
#146	ZNF69	20	23	43	2797.393
#147	ZIC2	20	14	34	1990.778
#148	ADNP	20	12	32	583.59
#149	BCL6	19	20	39	2273.048
#150	ELF4	19	16	35	1431.484
#151	ZNF281	19	13	32	1304.086
#152	BATF3	19	15	34	2781.808
#153	TAL1	19	11	30	656.679
#154	ZNF219	19	16	35	2185.757
#155	LZTS1	19	10	29	1034.455
#156	STAT4	19	6	25	384.312
#157	ALS2CR8	19	13	32	451.27
#158	TRIM22	18	8	26	332.258
#159	NFX1	18	11	29	938.067
#160	CSRNP1	18	13	31	1734.904
#161	TFCP2	18	9	27	2125.977
#162	ATF1	18	8	26	645.904
#163	NFIX	18	20	38	2326.043
#164	PRRX2	18	15	33	596.998
#165	HOXC9	18	6	24	672.869
#166	TWIST1	18	14	32	851.763
#167	STAT5B	18	18	36	1211.747
#168	KLF11	18	16	34	322.939
#169	RB1	18	9	27	1871.122
#170	ZNF217	18	17	35	1305.181
#171	FOXO1	18	15	33	1227.945
#172	PLSCR1	18	16	34	2160.653
#173	TBX2	17	10	27	196.294
#174	NR2F1	17	14	31	487.589
#175	ZNF18	17	18	35	2420.908
#176	TADA2A	17	19	36	1254.265
#177	MZF1	17	9	26	317.057
#178	MYT1	17	14	31	505.997
#179	CREB3L2	17	16	33	1072.434
#180	TRIM29	17	14	31	796.548
#181	NFYA	17	9	26	225.579
#182	TRPS1	17	13	30	914.987
#183	TFAP2A	17	11	28	378.817
#184	HOXB13	17	22	39	1477.72
#185	REL	17	13	30	841.079
#186	ZSCAN18	17	17	34	1962.493
#187	FOXQ1	17	15	32	2687.277
#188	PPARD	17	11	28	454.237
#189	NKX2-5	17	10	27	2896.851
#190	TCF3	16	11	27	585.853
#191	ZNF83	16	11	27	1988.162
#192	SOX7	16	16	32	2567.409
#193	PITX1	16	22	38	3239.125
#194	HOXB1	16	12	28	940.661
#195	SALL2	16	18	34	1068.262
#196	KLF9	16	17	33	1507.193
#197	ARNT2	16	23	39	957.497
#198	CTNNB1	16	15	31	2403.453
#199	LASS2	16	14	30	468.909
#200	BCL11B	16	6	22	2689.109
#201	TFAP2B	16	20	36	1813.031
#202	HOXA5	16	7	23	185.378
#203	ZNF187	16	19	35	3543.527
#204	ATF4	16	12	28	265.867
#205	ELK4	16	15	31	456.35
#206	ZNF165	15	18	33	1139.067
#207	HOXC8	15	9	24	526.147
#208	SREBF2	15	16	31	1195.567
#209	PBX3	15	20	35	2635.75
#210	SOX9	15	16	31	932.15
#211	ATF3	15	13	28	848.797
#212	ZNF175	15	24	39	5396.312
#213	LHX2	15	25	40	2270.467
#214	RELB	15	12	27	1206.449
#215	ARNT	15	23	38	1404.731
#216	NR5A2	14	15	29	807.792
#217	YEATS4	14	22	36	1731.464
#218	HMG20B	14	13	27	236.272
#219	MEIS2	14	11	25	434.092
#220	TBX10	14	15	29	3360.01
#221	HSF4	14	20	34	550.893
#222	ZFHX3	14	22	36	1360.795
#223	RAX2	14	8	22	495.873
#224	NR3C2	14	21	35	1580.615
#225	VDR	14	19	33	1687.658
#226	HOXB4	14	4	18	570.582
#227	TFAP2C	14	18	32	803.553
#228	ZNF134	14	18	32	1195.397
#229	SMAD1	14	11	25	641.57
#230	SOX12	14	24	38	1103.735
#231	CEBPA	14	11	25	884.538
#232	FOS	14	6	20	2191.865
#233	HOMEZ	14	15	29	2561.782
#234	HOXB3	14	11	25	2074.458
#235	FOSB	13	4	17	459.465
#236	SOX30	13	15	28	1670.242
#237	TEAD2	13	11	24	399.937
#238	HOXC13	13	11	24	1275.486
#239	CBFA2T2	13	14	27	602.763
#240	MAFB	13	12	25	1072.164
#241	IRF4	13	7	20	1979.67
#242	SIX4	13	16	29	3395.865
#243	ZNF85	13	13	26	249.395
#244	POU5F1	13	22	35	1146.729
#245	EGR2	13	15	28	1936.05
#246	HHEX	13	23	36	1517.476
#247	ETV7	13	12	25	829.209
#248	HOXA9	13	9	22	1043.211
#249	RUNX1T1	13	11	24	3189.256
#250	FOXP4	13	20	33	1108.491
#251	HOXD3	13	14	27	1040.692
#252	MEF2D	13	17	30	364.704
#253	IRF6	13	13	26	1183.443
#254	NFATC1	13	21	34	6906.702
#255	LEF1	13	22	35	1582.266
#256	MTA1	13	20	33	1873.428
#257	ZNF236	13	16	29	531.752
#258	FOXP1	12	22	34	2530.556
#259	IRF9	12	10	22	1937.912
#260	TBX3	12	21	33	753.874
#261	NR1H3	12	18	30	1066.843
#262	PAX6	12	13	25	1601.327
#263	GRHL3	12	31	43	2061.385
#264	ZNF24	12	11	23	1870.466
#265	MSX2	12	20	32	504.475
#266	HOXD4	12	13	25	506.042
#267	NFATC4	12	22	34	7783.266
#268	FOXF2	12	10	22	3043.696
#269	MEIS1	12	27	39	2240.044
#270	KLF4	12	15	27	1838.674
#271	BACH2	12	15	27	1227.285
#272	ZKSCAN1	11	9	20	518.043
#273	HOXC4	11	11	22	383.641
#274	ETS2	11	17	28	433.253
#275	CREB5	11	22	33	545.64
#276	SNAI3	11	8	19	510.433
#277	GATA2	11	28	39	2659.204
#278	BHLHE41	11	21	32	861.279
#279	IRF7	11	20	31	2338.047
#280	ASCL2	11	30	41	1301.813
#281	ZNF92	11	23	34	692.838
#282	ZHX3	11	20	31	1210.964
#283	SOX18	11	16	27	6041.827
#284	ZNF628	11	15	26	582.157
#285	MSX1	11	19	30	1273.832
#286	ZSCAN5A	11	25	36	892.271
#287	SREBF1	11	16	27	334.422
#288	ETV4	11	19	30	1157.284
#289	ATF2	11	14	25	342.818
#290	DDIT3	11	20	31	1093.221
#291	ZNF397	11	22	33	770.134
#292	PROX1	11	21	32	2384.306
#293	IRF1	11	10	21	214.416
#294	ELK3	11	20	31	1244.524
#295	HES1	11	21	32	923.449
#296	HOXA3	11	11	22	2106.114
#297	ZSCAN2	11	24	35	1266.604
#298	ZNF33A	11	12	23	1066.312
#299	TP63	10	19	29	334.654
#300	FOXD1	10	25	35	1185.524
#301	IRX2	10	26	36	1419.946
#302	CUX2	10	24	34	1723.486
#303	HOXC10	10	12	22	1155.284
#304	PPARG	10	15	25	481.99
#305	ZFP42	10	19	29	1194.706
#306	HLF	10	18	28	437.487
#307	HIF1A	10	20	30	671.74
#308	NR4A2	10	21	31	916.329
#309	RUNX1	10	17	27	700.849
#310	EGR1	10	12	22	1153.256
#311	THRA	10	16	26	1057.069
#312	ZNF93	10	17	27	722.799
#313	MEOX2	10	10	20	154.888
#314	VAV1	10	10	20	107.518
#315	LHX1	10	15	25	744.741
#316	VAX2	10	22	32	1001.832
#317	ZNF140	10	18	28	1284.345
#318	CREM	10	15	25	1422.161
#319	TRIM25	10	19	29	1188.492
#320	CLOCK	10	17	27	724.554
#321	MEF2A	10	21	31	442.961
#322	HMGA1	10	12	22	353.746
#323	ZKSCAN2	10	17	27	535.999
#324	HOXA7	10	7	17	1521.66
#325	IKZF4	10	16	26	563.393
#326	GATAD2B	10	18	28	680.971
#327	RXRG	10	13	23	1922.457
#328	HES5	9	18	27	1472.334
#329	HOXC6	9	15	24	500.396
#330	DMRT2	9	20	29	817.2
#331	LMX1B	9	13	22	336.128
#332	ZXDA	9	20	29	940.27
#333	SOX4	9	18	27	955.661
#334	REST	9	22	31	590.61
#335	NFIC	9	19	28	677.392
#336	NR4A3	9	11	20	572.67
#337	HOXB2	9	21	30	720.866
#338	RCAN1	9	24	33	1081.243
#339	WNT5A	9	24	33	604.495
#340	CBFA2T3	9	24	33	1650.984
#341	EOMES	9	8	17	122.118
#342	HOXA6	9	7	16	1346.343
#343	NKX3-2	9	15	24	339.095
#344	MAFG	9	18	27	759.494
#345	ASCL1	9	23	32	1534.821
#346	BCL3	9	23	32	698.017
#347	FOXD4L1	9	22	31	1667.274
#348	RUNX2	9	16	25	1163.263
#349	NR1D2	9	21	30	1235.567
#350	PHF5A	9	14	23	1178.412
#351	LBX2	9	24	33	1296.523
#352	FOXI1	8	27	35	1889.592
#353	NPAS2	8	24	32	1233.126
#354	CSRNP3	8	22	30	635.131
#355	IKZF1	8	11	19	278.734
#356	MLXIPL	8	20	28	717.064
#357	HNF4G	8	25	33	952.004
#358	HNF4A	8	18	26	1148.133
#359	RBPJ	8	22	30	827.226
#360	PBX1	8	21	29	877.31
#361	TAF5L	8	25	33	830.871
#362	TRERF1	8	21	29	701.44
#363	STAT5A	8	16	24	347.608
#364	ZNF256	8	13	21	1053.761
#365	HAND1	8	16	24	2699.02
#366	GATA5	8	17	25	1196.784
#367	ARX	8	24	32	962.839
#368	SOLH	8	25	33	1081.692
#369	MMP14	8	8	16	1934.708
#370	PPARA	8	11	19	575.357
#371	SIX1	8	25	33	2213.162
#372	IRX6	8	24	32	1791.934
#373	TEF	8	23	31	969.694
#374	ZNF287	8	21	29	853.734
#375	LHX8	8	13	21	2124.924
#376	NR2F2	8	24	32	1111.632
#377	HOXB7	8	14	22	1584.037
#378	SMAD9	8	22	30	2442.327
#379	NR2C1	7	20	27	612.855
#380	HMBOX1	7	19	26	2571.305
#381	ZNF192	7	29	36	610.918
#382	NR3C1	7	26	33	693.488
#383	TFAP4	7	20	27	2085.156
#384	TLX2	7	16	23	7747.861
#385	GTF2H2	7	13	20	305.568
#386	HMX2	7	25	32	2666.575
#387	NFE2L3	7	21	28	360.408
#388	PAX7	7	17	24	760.361
#389	FOXC2	7	26	33	811.678
#390	SIX2	7	23	30	1089.597
#391	GCM1	7	22	29	499.848
#392	GSC	7	27	34	803.768
#393	HOXD1	7	23	30	1406.348
#394	TFEB	7	14	21	1447.177
#395	ZHX2	7	20	27	547.393
#396	ZNF197	7	29	36	899.26
#397	ESRRG	7	24	31	1104.738
#398	BRD8	7	15	22	607.197
#399	DLX2	7	14	21	371.144
#400	TLX3	7	21	28	1105.572
#401	HOXB5	7	9	16	1045.871
#402	FOXJ1	7	24	31	2244.706
#403	CITED2	7	23	30	1811.017
#404	ELF3	7	19	26	2877.359
#405	ONECUT2	6	19	25	715.183
#406	FOXN4	6	15	21	1331.685
#407	DLX3	6	30	36	661.141
#408	TFDP2	6	27	33	1407.46
#409	BATF	6	28	34	917.738
#410	SMAD6	6	22	28	1483.498
#411	ZNF323	6	22	28	698.167
#412	PBX4	6	25	31	493.953
#413	HEY2	6	21	27	2749.945
#414	SIM1	6	14	20	719.121
#415	FOXD2	6	21	27	1083.955
#416	ZNF167	6	24	30	764.556
#417	ARNTL	6	21	27	758.104
#418	JUN	6	12	18	505.381
#419	CITED1	6	25	31	777.015
#420	SATB2	6	27	33	838.065
#421	PLAG1	6	24	30	1210.18
#422	IRX4	6	37	43	1655.68
#423	MESP1	6	32	38	2705.661
#424	KLF2	6	18	24	400.646
#425	SCAND3	6	24	30	952.562
#426	MITF	6	18	24	594.885
#427	FOXA3	6	28	34	1431.102
#428	ZFHX4	6	15	21	295.25
#429	DLX1	6	26	32	1486.581
#430	HESX1	6	22	28	567.116
#431	HOXB8	5	17	22	5771.964
#432	NFATC3	5	22	27	284.811
#433	TAF7	5	19	24	583.199
#434	LHX6	5	25	30	1303.896
#435	HOXD11	5	18	23	336.735
#436	HOXB6	5	6	11	607.651
#437	ZNF202	5	25	30	349.015
#438	EGR3	5	21	26	813.451
#439	NFE2	5	27	32	1346.314
#440	HR	5	21	26	457.075
#441	HOPX	5	25	30	519.04
#442	CEBPD	5	16	21	668.426
#443	NR0B1	5	15	20	1481.333
#444	RFX3	5	20	25	536.564
#445	ZFPM2	5	11	16	60.26
#446	FOXO4	5	18	23	742.507
#447	EN2	5	20	25	393.249
#448	ZNF71	5	24	29	1053.814
#449	ZNF643	5	21	26	374.405
#450	POU2F3	5	17	22	504.473
#451	IRX5	5	17	22	1365.522
#452	KLF12	5	23	28	580.559
#453	TBX1	5	29	34	851.86
#454	PKNOX2	5	14	19	282.511
#455	HEY1	5	20	25	525.635
#456	SMAD3	5	22	27	471.174
#457	EMX1	5	21	26	760.905
#458	FOXD4	5	12	17	1142.335
#459	KLF6	5	19	24	968.097
#460	TP53	4	17	21	384.919
#461	MKX	4	38	42	904.192
#462	ZSCAN29	4	26	30	655.737
#463	PCGF6	4	14	18	37.235
#464	RARB	4	23	27	366.419
#465	PEG3	4	33	37	1003.942
#466	SATB1	4	23	27	894.736
#467	ZNF132	4	23	27	436.587
#468	ZIM2	4	11	15	680.067
#469	KLF15	4	24	28	980.645
#470	ZNF81	4	22	26	328.717
#471	VTN	4	14	18	1112.969
#472	HMX1	4	15	19	748.74
#473	HOXD9	4	20	24	402.963
#474	OVOL1	4	25	29	560.144
#475	WT1	3	26	29	903.532
#476	CCRN4L	3	30	33	293.387
#477	FOSL1	3	23	26	177.899
#478	ZNF135	3	18	21	1088.466
#479	HOXD8	3	19	22	600.472
#480	IRF5	3	23	26	799.904
#481	PAX8	3	30	33	414.939
#482	MXD1	3	20	23	328.35
#483	ZNF155	3	23	26	805.831
#484	ISX	3	19	22	528.563
#485	SOX15	3	26	29	673.753
#486	TCF20	3	15	18	399.758
#487	TAF13	3	20	23	335.529
#488	ZNF483	3	15	18	235.03
#489	NKX3-1	2	27	29	256.423
#490	HOXB9	2	17	19	284.414
#491	GRHL2	2	20	22	472.45
#492	TLX1	2	14	16	135.464
#493	FOXI2	2	17	19	952.613
#494	HOXA10	1	18	19	1419.847
#495	SCML1	1	26	27	228.784
#496	CNOT7	1	22	23	59.557
#497	RORB	1	25	26	232.298
#498	ZFP37	1	28	29	117.389
#499	SIM2	1	27	28	79.641
#500	ZNF268	0	30	30	0