Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	BCL3	34	3	37	718.63
#2	ZNF131	31	1	32	94.18
#3	CRX	28	1	29	111.306
#4	KLF7	27	8	35	11413.453
#5	ZNF175	27	5	32	4028.102
#6	ZNF444	26	4	30	419.101
#7	C5orf41	26	3	29	332.63
#8	POU4F2	25	8	33	8970.129
#9	NOTCH1	24	8	32	4609.425
#10	SUPT6H	23	3	26	348.563
#11	RNF4	23	2	25	273.273
#12	ELF4	22	2	24	49.761
#13	FOXA3	22	7	29	638.236
#14	DLX3	22	7	29	1256.884
#15	TCF7	22	0	22	0
#16	MLL	21	4	25	2341.185
#17	ZNF238	20	3	23	137.403
#18	YY1	20	5	25	4421.116
#19	ST18	20	9	29	2745.242
#20	ADNP2	20	9	29	885.461
#21	HOXB7	20	7	27	1734.99
#22	CDKN2A	20	2	22	253.927
#23	RB1	20	2	22	155.638
#24	HOXC6	19	9	28	1539.612
#25	MXD1	19	3	22	470.518
#26	TBX5	19	6	25	1628.289
#27	IRF4	19	6	25	2209.982
#28	TFAP2E	19	7	26	839.064
#29	FOXJ1	19	1	20	107.027
#30	SMAD4	18	8	26	1070.531
#31	ARX	18	3	21	197.951
#32	DDIT3	18	3	21	203.387
#33	SOX17	18	6	24	219.075
#34	RERE	18	5	23	865.628
#35	ZNF639	18	4	22	701.784
#36	IRF5	18	3	21	1096.813
#37	STAT3	18	4	22	240.152
#38	HIC1	18	10	28	2445.716
#39	LHX5	18	4	22	798.642
#40	TFAM	18	8	26	540.638
#41	ZNF165	17	2	19	1711.598
#42	ESX1	17	5	22	1901.603
#43	BATF2	17	7	24	579.978
#44	SNAPC4	17	4	21	251.721
#45	ZNF24	17	5	22	1219.578
#46	LZTR1	17	6	23	1509.466
#47	ZKSCAN4	17	8	25	1373.405
#48	BARX1	17	2	19	84.549
#49	GLI2	17	5	22	1231.872
#50	LHX3	17	4	21	1798.507
#51	ATF2	16	10	26	3776.963
#52	PPARA	16	9	25	3301.266
#53	SIX1	16	3	19	752.314
#54	ZNF81	16	1	17	67.103
#55	TLX2	16	5	21	363.05
#56	SALL2	16	10	26	4476.464
#57	SMAD5	16	5	21	758.244
#58	NKX2-1	15	7	22	2447.966
#59	RBPJ	15	5	20	874.631
#60	ZNF397	15	8	23	2310.853
#61	MYT1	15	4	19	204.591
#62	TMEM229A	15	7	22	4934.123
#63	MLX	15	10	25	1086.473
#64	IRX1	15	4	19	734.799
#65	CCRN4L	15	6	21	722.449
#66	PKNOX1	15	8	23	3273.673
#67	SP1	15	10	25	2067.778
#68	ZNF148	14	5	19	2209.425
#69	GRHL3	14	6	20	4179.515
#70	HESX1	14	8	22	749.138
#71	AHCTF1	14	6	20	1456.477
#72	RBPJL	14	10	24	2300.94
#73	ZFPM1	14	4	18	1484.797
#74	IRX3	14	7	21	1251.156
#75	POU6F2	14	12	26	1668.924
#76	DMRT1	14	6	20	904.241
#77	RAX2	14	8	22	390.351
#78	RARA	14	9	23	6367.271
#79	CREBL2	14	6	20	2866.203
#80	SOX4	14	16	30	2274.83
#81	TBP	14	6	20	1642.954
#82	OTX1	14	8	22	1658.397
#83	SIN3A	14	13	27	4215.741
#84	OLIG2	14	3	17	1266.717
#85	CREB1	13	12	25	1677.6
#86	TEF	13	5	18	196.34
#87	ZSCAN1	13	6	19	1917.346
#88	E4F1	13	7	20	921.891
#89	FOXM1	13	11	24	3423.928
#90	ZNF174	13	4	17	2240.506
#91	ERF	13	8	21	3157.357
#92	ARNTL2	13	3	16	213.574
#93	ARNT	13	6	19	599.999
#94	GATAD2A	13	8	21	745.572
#95	HMGB1	13	6	19	596.808
#96	HOXC4	13	7	20	648.578
#97	MEIS3	13	6	19	1117.661
#98	ZSCAN10	13	5	18	1226.866
#99	NFE2L2	13	6	19	2775.163
#100	ESR1	13	8	21	429.407
#101	MYF6	13	6	19	2167.655
#102	TBX3	13	13	26	5921.85
#103	RUNX1T1	13	10	23	4760.604
#104	TFDP3	13	6	19	758.662
#105	FOXP2	13	3	16	1322.834
#106	PRDM1	13	6	19	911.432
#107	ZFP36L1	13	10	23	1344.884
#108	TAL1	12	9	21	1227.251
#109	KDM5B	12	5	17	634.775
#110	SOX7	12	7	19	1914.849
#111	EN2	12	6	18	1913.494
#112	ZNF85	12	14	26	4236.004
#113	VENTX	12	5	17	1381.392
#114	NOLC1	12	6	18	1401.026
#115	MAF	12	9	21	2156.263
#116	ZNF133	12	6	18	887.005
#117	PURB	12	4	16	101.281
#118	ZNF256	12	10	22	1957.861
#119	FOXD3	12	5	17	1117.522
#120	ZNF277	12	6	18	325.656
#121	ZEB2	12	8	20	1063.848
#122	JUND	12	5	17	171.351
#123	TSC22D4	12	15	27	3322.301
#124	ARNT2	12	8	20	785.718
#125	C1orf85	12	6	18	2555.529
#126	PHF1	12	7	19	1534.423
#127	USF1	12	8	20	1555.806
#128	HOXA11	12	11	23	2611.787
#129	NR1D1	12	3	15	240.349
#130	RARG	12	13	25	1097.282
#131	AR	12	14	26	2980.297
#132	NEUROD1	12	9	21	1703.557
#133	CREBZF	12	3	15	505.092
#134	TP63	11	7	18	518.931
#135	NFE2	11	8	19	1370.112
#136	TRIM29	11	12	23	2180.971
#137	ZFP90	11	6	17	446.937
#138	MAFA	11	8	19	539.561
#139	GTF2IRD1	11	9	20	2941.49
#140	ZEB1	11	6	17	166.12
#141	EN1	11	14	25	4548.909
#142	ZSCAN16	11	10	21	1932.305
#143	PHF5A	11	7	18	1634.273
#144	E2F8	11	10	21	2766.932
#145	LHX9	11	8	19	1322.861
#146	ZC3H8	11	5	16	502.637
#147	HIF1A	11	6	17	2195.066
#148	HCFC1	11	10	21	1947.762
#149	HOXA9	11	12	23	1357.202
#150	HDAC1	11	12	23	1147.178
#151	TFDP2	11	11	22	1054.354
#152	EGR2	11	7	18	1069.231
#153	MAFK	11	15	26	3906.385
#154	NFYC	11	6	17	1027.896
#155	FOXC1	11	5	16	338.979
#156	CREB3L1	11	8	19	1637.197
#157	PBX3	11	5	16	2499.133
#158	E2F6	11	2	13	168.464
#159	PLAGL2	11	9	20	859.575
#160	PAX6	11	9	20	1304.424
#161	CSRNP3	11	6	17	435.113
#162	AEBP1	11	9	20	3216.705
#163	NR2C1	10	2	12	54.907
#164	POU3F4	10	3	13	400.188
#165	TCF21	10	5	15	597.598
#166	ZFPM2	10	3	13	302.102
#167	FBXW7	10	10	20	2075.712
#168	TBX4	10	8	18	222.418
#169	NFE2L1	10	6	16	827.444
#170	HIF3A	10	4	14	856.149
#171	SCAND2	10	8	18	1055.642
#172	VSX1	10	9	19	2655.316
#173	ELF5	10	7	17	755.943
#174	POU5F2	10	8	18	1924.773
#175	ZSCAN29	10	10	20	2693.418
#176	ELF3	10	4	14	490.453
#177	ESRRA	10	5	15	1035.659
#178	ELK4	10	6	16	1069.814
#179	EOMES	10	10	20	1737.017
#180	ZNF37A	10	4	14	791.982
#181	NFKB1	10	9	19	569.732
#182	THRB	10	13	23	2377.68
#183	CNOT8	10	11	21	5456.639
#184	NEUROD2	10	10	20	2008.679
#185	RELA	10	12	22	2888.317
#186	WNT5A	10	11	21	1298.86
#187	ZXDC	10	8	18	3878.747
#188	TSC22D2	10	8	18	1392.839
#189	ZNF202	10	16	26	2178.162
#190	AFF1	10	8	18	3626.271
#191	ZNF215	10	7	17	2607.131
#192	LMX1B	10	10	20	1269.961
#193	PGR	10	7	17	534.283
#194	TULP4	10	6	16	735.57
#195	SMAD1	10	11	21	1569.383
#196	RAX	10	8	18	756.095
#197	JUN	10	12	22	3711.888
#198	LMO4	10	7	17	574.013
#199	ZNF232	10	10	20	2190.366
#200	CREB3	9	10	19	1440.503
#201	CNOT7	9	10	19	3480.895
#202	MSX2	9	7	16	2989.334
#203	HOXB5	9	8	17	1744.683
#204	PAX3	9	8	17	627.567
#205	RCOR2	9	9	18	2945.017
#206	MITF	9	7	16	1485.647
#207	TSHZ3	9	10	19	1195.427
#208	ATF6	9	6	15	1206.482
#209	NFIX	9	7	16	874.412
#210	PCGF6	9	7	16	383.207
#211	LHX1	9	7	16	2333.99
#212	FOXO3	9	7	16	2064.636
#213	ZKSCAN1	9	9	18	1325.83
#214	HES5	9	4	13	807.919
#215	NFATC2	9	13	22	2376.84
#216	RHOXF2B	9	6	15	269.378
#217	HMGA2	9	10	19	1042.388
#218	ZBTB48	9	9	18	1804.816
#219	BATF3	9	7	16	828.057
#220	E2F4	9	12	21	1869.374
#221	STAT2	9	11	20	3154.86
#222	KCNH8	9	12	21	2044.077
#223	TBX19	9	8	17	595.431
#224	TAF4	9	5	14	2304.708
#225	FOXD2	9	14	23	1315.582
#226	MGA	9	6	15	601.025
#227	SOX12	9	7	16	2974.52
#228	BTAF1	9	14	23	2853.799
#229	GATA2	9	6	15	1115.614
#230	FOXR1	9	11	20	906.548
#231	TP73	8	8	16	1952.678
#232	SMAD2	8	14	22	2415.474
#233	KLF6	8	8	16	638.055
#234	CBFB	8	14	22	1660.395
#235	NFIA	8	11	19	1536.826
#236	MLLT10	8	8	16	605.988
#237	SRF	8	11	19	1368.527
#238	GTF2I	8	8	16	1400.34
#239	NFKB2	8	9	17	1254.216
#240	ZNF207	8	8	16	1823.988
#241	DMTF1	8	9	17	1650.523
#242	MYT1L	8	9	17	2621.877
#243	TP53	8	8	16	543.129
#244	ZNF449	8	3	11	65.323
#245	HSF2	8	6	14	524.535
#246	TCF7L2	8	6	14	714.671
#247	FOXK1	8	14	22	2049.393
#248	ZNF19	8	9	17	1040.01
#249	OVOL1	8	7	15	793.311
#250	NR1H2	8	11	19	1519.065
#251	ETV4	8	11	19	2465.51
#252	HMGA1	8	7	15	1232.815
#253	ZNF75D	8	6	14	773.816
#254	TFDP1	8	13	21	1962.785
#255	IRX4	8	11	19	1096.078
#256	NFYA	8	8	16	556.449
#257	IRF3	8	10	18	626.931
#258	RORA	8	5	13	824.708
#259	ZFP42	8	9	17	727.685
#260	KLF12	8	5	13	124.419
#261	RHOXF2	8	3	11	56.737
#262	MYF5	8	10	18	1356.237
#263	ATF3	8	8	16	843.768
#264	BACH1	8	4	12	1468.289
#265	USF2	8	11	19	5601.481
#266	TCF3	8	6	14	697.862
#267	ELF1	7	7	14	664.379
#268	GRHL2	7	8	15	2452.587
#269	LHX2	7	13	20	2193.014
#270	MEIS1	7	13	20	2093.311
#271	FOXA1	7	6	13	1106.89
#272	FOXO4	7	9	16	830.599
#273	NFIB	7	8	15	1692.504
#274	SNAPC5	7	10	17	1360.316
#275	GSC2	7	7	14	366.938
#276	FOXG1	7	9	16	1464.749
#277	ZNF33A	7	7	14	1026.184
#278	RUNX1	7	10	17	1476.251
#279	CTNNB1	7	16	23	1854.307
#280	ETV7	7	10	17	4071.748
#281	ZIC5	7	12	19	2944.913
#282	TGIF2LY	7	11	18	1332.849
#283	SOX9	7	8	15	1087.441
#284	BRD8	7	12	19	1316.354
#285	BLZF1	7	13	20	1347.944
#286	SOX2	7	11	18	885.391
#287	MLXIPL	7	13	20	2212.843
#288	FOXE1	7	13	20	2255.308
#289	TSC22D3	7	12	19	1573.466
#290	POU3F2	7	9	16	601.807
#291	XBP1	7	8	15	1112.423
#292	HOXC8	7	11	18	1899.808
#293	SMAD9	7	13	20	1090.33
#294	NR1D2	7	8	15	920.695
#295	TWIST1	7	11	18	2767.231
#296	DMRT2	7	11	18	2699.43
#297	FOXL1	7	9	16	543.259
#298	ZNF134	7	11	18	2677.067
#299	GLIS3	7	13	20	2482.675
#300	FOXI3	7	13	20	2648.325
#301	L3MBTL4	7	18	25	4192.979
#302	JUNB	7	12	19	1025.414
#303	HOXA10	7	9	16	1244.911
#304	MTA3	7	14	21	2148.589
#305	ETV6	7	14	21	3049.515
#306	NFAT5	6	9	15	1382.719
#307	ZNF35	6	11	17	2857.601
#308	ELK1	6	13	19	1212.304
#309	STAT5B	6	13	19	619.714
#310	ZNF219	6	8	14	1366.951
#311	SMAD3	6	12	18	789.852
#312	IRX2	6	12	18	1068.124
#313	ZNF189	6	16	22	1991.705
#314	ZIC1	6	6	12	411.7
#315	RORC	6	12	18	1785.818
#316	MNT	6	11	17	1698.278
#317	ZSCAN2	6	6	12	116.201
#318	PTH	6	9	15	479.199
#319	BARHL1	6	9	15	838.347
#320	STRN3	6	11	17	564.385
#321	TRIM25	6	10	16	509.809
#322	NR2E3	6	5	11	333.754
#323	HNF1A	6	8	14	1458.265
#324	BTG2	6	7	13	483.257
#325	PPARD	6	8	14	1514.252
#326	PPARG	6	10	16	2073.414
#327	ZKSCAN2	6	15	21	1812.109
#328	ZNF500	6	11	17	730.827
#329	ATF7	6	10	16	492.098
#330	SIX3	6	9	15	621.404
#331	PAX8	6	10	16	2774.457
#332	REL	6	8	14	1599.635
#333	MNX1	6	13	19	1350.712
#334	PBX1	6	6	12	1577.513
#335	NR2F1	6	6	12	1097.365
#336	NFATC4	6	7	13	164.876
#337	VDR	6	13	19	2095.923
#338	TRIM28	6	8	14	649.669
#339	FOXJ2	6	14	20	1863.796
#340	ELK3	6	10	16	1188.503
#341	E2F2	6	13	19	1310.339
#342	NFE2L3	6	11	17	1452.206
#343	RXRA	6	6	12	434.001
#344	ATF6B	6	16	22	2107.403
#345	FOXK2	6	10	16	935.431
#346	ZHX2	5	11	16	1023.996
#347	HOXB3	5	8	13	740.053
#348	RORB	5	9	14	575.885
#349	EGR1	5	11	16	1046.16
#350	ZXDA	5	13	18	919.747
#351	NFX1	5	12	17	2930.731
#352	HOXA4	5	10	15	842.987
#353	IRX5	5	14	19	801.061
#354	SOX8	5	10	15	1039.497
#355	GTF2H3	5	9	14	1333.681
#356	MYPOP	5	14	19	2014.71
#357	EGR4	5	14	19	1538.986
#358	PKNOX2	5	8	13	1320.363
#359	FOXD4	5	10	15	1277.237
#360	FOXJ3	5	10	15	902.912
#361	NKX6-1	5	14	19	1034.158
#362	PHTF1	5	16	21	1730.878
#363	MECOM	5	10	15	702.2
#364	TFEC	5	12	17	640.478
#365	GCFC1	5	7	12	501.072
#366	MYOG	5	8	13	699.132
#367	TCFL5	5	10	15	1048.541
#368	MEOX1	5	12	17	1361.814
#369	IKZF1	5	16	21	1295.856
#370	ZNF167	5	14	19	1075.791
#371	TSHZ2	5	14	19	1216.126
#372	FOSB	5	11	16	679.59
#373	SREBF1	5	8	13	818.295
#374	PFDN1	5	4	9	498.749
#375	CREB3L3	5	14	19	780.632
#376	ZNF187	5	15	20	2705.848
#377	POU3F3	5	8	13	828.692
#378	AFF4	5	15	20	880.476
#379	SCML1	5	4	9	548.44
#380	TSC22D1	5	6	11	790.955
#381	NR0B1	5	10	15	2928.639
#382	NPAS2	5	13	18	759.478
#383	SP140	5	11	16	1638.578
#384	DLX2	5	9	14	1737.92
#385	MAX	4	11	15	246.854
#386	ZNF45	4	6	10	376.379
#387	SIM2	4	10	14	1209.853
#388	FOXD1	4	11	15	647.784
#389	STAT1	4	14	18	1134.068
#390	ASCL2	4	10	14	1181.721
#391	SIX6	4	9	13	1726.66
#392	NRL	4	13	17	2498.439
#393	CEBPB	4	9	13	2398.748
#394	ZNF445	4	10	14	863.357
#395	ZNF70	4	11	15	403.656
#396	ESR2	4	12	16	1233.074
#397	SOLH	4	6	10	1684.945
#398	IRF1	4	8	12	493.958
#399	DRAP1	4	12	16	2113.698
#400	NFIL3	4	11	15	581.957
#401	UBN1	4	12	16	520.506
#402	ETS2	4	12	16	2239.608
#403	HOXD9	4	7	11	549.692
#404	PRRX1	4	7	11	973.228
#405	KLF15	4	12	16	456.832
#406	HMG20A	4	7	11	684.099
#407	HOPX	4	11	15	1264.311
#408	E2F1	4	8	12	858.321
#409	SPDEF	4	6	10	896.429
#410	ETV3	4	14	18	981.192
#411	PROX1	4	13	17	2441.103
#412	SOX5	4	8	12	934.386
#413	SPIB	4	6	10	164.467
#414	CREM	4	9	13	425.925
#415	HOXD13	4	11	15	756.524
#416	NKX2-3	4	6	10	225.29
#417	NKX1-2	3	11	14	309.748
#418	TFE3	3	13	16	327.433
#419	ANKRD30A	3	13	16	960.228
#420	DLX1	3	8	11	627.463
#421	SOX10	3	9	12	901.98
#422	FOS	3	10	13	900.761
#423	MYCN	3	11	14	614.28
#424	SOX30	3	9	12	454.228
#425	FOXN4	3	10	13	851.664
#426	EVX1	3	5	8	229.691
#427	ARNTL	3	10	13	505.963
#428	ZBTB25	3	14	17	771.391
#429	SCAND3	3	9	12	477.917
#430	ZFHX4	3	13	16	1134.545
#431	ETV3L	3	5	8	432.165
#432	CREB3L2	3	7	10	535.182
#433	ALX1	3	9	12	916.193
#434	ZNF140	3	14	17	662.781
#435	POU2F2	3	10	13	359.468
#436	KLF3	3	12	15	669.119
#437	ZRANB2	3	10	13	607.948
#438	ZNF213	3	12	15	432.621
#439	LEF1	3	9	12	267.344
#440	ZSCAN18	3	12	15	491.777
#441	HNF4A	3	6	9	532.653
#442	ZFHX2	3	9	12	339.182
#443	NR3C1	3	14	17	1015.391
#444	FOXP1	3	9	12	2257.765
#445	TFCP2	3	12	15	405.483
#446	EHF	3	10	13	1054.321
#447	FOXP3	3	17	20	737.384
#448	RFXANK	3	14	17	1432.071
#449	TCF4	3	13	16	594.324
#450	ASCL1	3	17	20	1765.88
#451	HOXB6	3	15	18	367.878
#452	CITED2	3	10	13	299.218
#453	CUX1	3	5	8	399.019
#454	STAT6	3	12	15	1474.828
#455	TBX6	2	17	19	284.444
#456	SP4	2	10	12	450.167
#457	PITX1	2	10	12	282.924
#458	NCOR1	2	13	15	299.898
#459	KLF16	2	9	11	260.289
#460	NFYB	2	11	13	586.084
#461	LHX6	2	8	10	873.631
#462	CEBPA	2	10	12	634.022
#463	ESRRB	2	14	16	399.8
#464	CLOCK	2	5	7	420.289
#465	CTBP1	2	10	12	161.439
#466	CSDA	2	6	8	411.922
#467	POU5F1	2	7	9	497.834
#468	RCOR1	2	13	15	453.666
#469	ZSCAN4	2	9	11	146.259
#470	LHX4	2	11	13	328.629
#471	ZNF193	2	6	8	265.953
#472	CREBBP	2	10	12	310.01
#473	FLI1	2	9	11	246.217
#474	ONECUT2	2	6	8	113.86
#475	EMX1	2	11	13	260.769
#476	CREB3L4	2	11	13	444.345
#477	JDP2	2	7	9	550.501
#478	CTCF	2	13	15	551.465
#479	NFATC3	1	14	15	61.908
#480	ZNF236	1	5	6	132.197
#481	ATF4	1	15	16	205.955
#482	RELB	1	4	5	59.863
#483	TFAP2A	1	13	14	193.915
#484	FUBP1	1	6	7	42.09
#485	ZNF135	1	11	12	390.263
#486	FOSL2	1	9	10	124.838
#487	SOX11	1	8	9	468.914
#488	HNF1B	1	17	18	224.774
#489	TPRX1	1	13	14	712.018
#490	FOSL1	1	14	15	881.065
#491	MEIS3P1	1	11	12	471.154
#492	GABPB1	1	8	9	160.206
#493	ZSCAN12	1	12	13	171.589
#494	TCF7L1	1	15	16	199.605
#495	TCF20	1	10	11	573.777
#496	SOX6	0	9	9	0
#497	LCOR	0	14	14	0
#498	MYC	0	13	13	0
#499	TRERF1	0	10	10	0
#500	SUPT4H1	0	9	9	0