Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FLI1	69	2	71	250.813
#2	TCF4	53	8	61	2372.013
#3	ZNF444	51	7	58	1856.862
#4	SIX5	48	8	56	1054.62
#5	ELK3	46	5	51	1218.531
#6	IKZF1	46	4	50	220.078
#7	SOX15	45	6	51	785.832
#8	ERG	45	6	51	417.179
#9	MLXIPL	42	4	46	1690.026
#10	ENO1	42	6	48	753.568
#11	ATF5	41	0	41	0
#12	FOXP3	40	5	45	109.573
#13	ZFPM2	39	7	46	407.776
#14	ZNF281	39	7	46	1562.68
#15	USF2	39	6	45	336.562
#16	TEAD2	38	1	39	5.507
#17	SPDEF	38	2	40	21.635
#18	ZEB2	38	11	49	2097.435
#19	PBX1	37	9	46	9828.862
#20	ZNF445	36	3	39	736.874
#21	NFATC3	36	12	48	1626.666
#22	ECSIT	35	6	41	10659.955
#23	ZNF219	34	6	40	285.06
#24	TRIM22	34	4	38	687.325
#25	KLF12	34	8	42	540.172
#26	ELF4	33	11	44	2902.216
#27	GATA4	33	11	44	9155.934
#28	EBF1	31	8	39	294.06
#29	RUNX3	31	9	40	2286.078
#30	VDR	31	12	43	4929.714
#31	XBP1	30	11	41	3436.211
#32	FOXA3	30	8	38	1287.685
#33	ESRRA	30	10	40	1301.981
#34	RUNX2	29	8	37	2511.412
#35	ZNF217	29	9	38	980.185
#36	EVX1	29	3	32	18.235
#37	ETS1	29	11	40	866.97
#38	BHLHE40	29	13	42	2113.774
#39	LEF1	29	13	42	2809.092
#40	MLX	28	5	33	907.395
#41	NFE2L3	28	12	40	3495.875
#42	PRDM1	28	10	38	2570.037
#43	CREM	27	8	35	1753.374
#44	E2F4	27	7	34	206.012
#45	TRIM25	27	7	34	1288.007
#46	FOXN2	27	10	37	2550.649
#47	RFX5	27	5	32	990.504
#48	NR2F6	27	7	34	231.871
#49	MNX1	26	10	36	669.975
#50	MEF2C	26	7	33	653.067
#51	HNF1A	25	11	36	3440.458
#52	KLF7	25	8	33	925.034
#53	PRRX1	25	8	33	1787.86
#54	CREB3L3	25	5	30	22745.975
#55	HOXA3	24	13	37	4908.685
#56	AEBP1	24	11	35	1855.076
#57	C11orf9	24	8	32	8976.763
#58	MAF	24	13	37	18175.78
#59	MYBL2	24	9	33	426.768
#60	HMGB2	23	8	31	1872.364
#61	TSHZ3	23	13	36	1516.396
#62	E2F3	23	9	32	688.491
#63	SMAD9	23	13	36	1913.188
#64	AHR	23	9	32	1153.953
#65	TSHZ2	22	9	31	1258.149
#66	BCL11B	22	10	32	1713.359
#67	MESP2	22	6	28	218.834
#68	RUNX1T1	22	7	29	1113.387
#69	BLZF1	21	9	30	670.736
#70	REST	21	7	28	11040.895
#71	HMX1	21	5	26	250.724
#72	ZFPM1	21	13	34	3719.884
#73	EDF1	21	10	31	2629.82
#74	HCLS1	21	6	27	1190.471
#75	NFYB	20	10	30	968.302
#76	IRF6	20	9	29	7427.481
#77	GATA1	20	7	27	2221.144
#78	NR5A2	20	10	30	36892.453
#79	ETS2	20	13	33	1839.133
#80	BHLHE41	20	16	36	5381.51
#81	MSL3	20	14	34	1157.249
#82	RCOR1	20	7	27	602.661
#83	KLF11	20	12	32	754.461
#84	KLF15	20	13	33	2998.843
#85	TBX3	19	14	33	8147.316
#86	PAX8	19	7	26	1829.617
#87	KLF16	19	8	27	1354.214
#88	NFIC	19	7	26	4429.04
#89	ARNTL2	19	13	32	5108.586
#90	FOXA2	19	10	29	5383.938
#91	TRPS1	19	5	24	248.112
#92	HOXB2	19	9	28	714.093
#93	PTTG1	19	9	28	939.704
#94	RUNX1	19	11	30	1076.473
#95	PITX3	18	8	26	418.594
#96	CEBPB	18	9	27	2160.67
#97	RBPJL	18	13	31	24595.985
#98	PPARD	18	4	22	331.5
#99	NR3C2	18	11	29	651.819
#100	IRF1	18	14	32	2482.896
#101	FEV	17	12	29	2913.402
#102	TWIST1	17	12	29	480.335
#103	ONECUT3	17	6	23	4006.951
#104	HOXB7	17	11	28	8738.992
#105	ZNF91	17	6	23	800.043
#106	ZBTB17	17	9	26	576.733
#107	CREBBP	16	9	25	752.991
#108	ZGLP1	16	8	24	3457.94
#109	HNF1B	16	8	24	1395.773
#110	SCMH1	16	6	22	913.478
#111	HNF4G	16	10	26	10398.439
#112	MYOD1	16	11	27	1266.86
#113	NFIL3	16	12	28	1179.496
#114	CBL	16	16	32	2268.815
#115	ETV1	16	13	29	1080.46
#116	REL	16	13	29	1285.542
#117	HOXB3	15	10	25	779.758
#118	TFEC	15	11	26	2364.732
#119	NR1I2	15	10	25	16777.799
#120	LASS6	15	13	28	2105.078
#121	BARHL1	15	11	26	880.661
#122	CBFA2T3	15	16	31	2869.128
#123	CSRNP2	15	13	28	1298.216
#124	MSRB2	15	10	25	2415.185
#125	STAT2	15	8	23	350.734
#126	CBFB	15	6	21	1409.316
#127	PPARA	15	7	22	881.007
#128	BTAF1	15	11	26	694.555
#129	PBX3	15	11	26	5589.053
#130	EPAS1	15	7	22	2942.056
#131	IRF2	14	7	21	862.658
#132	GLIS2	14	6	20	405.148
#133	KLF5	14	13	27	1088.94
#134	PCGF2	14	7	21	1444.645
#135	ZKSCAN1	14	10	24	2289.268
#136	E2F8	14	12	26	9764.34
#137	CDX2	14	6	20	1116.217
#138	CSRNP1	14	4	18	788.679
#139	SOLH	14	9	23	627.08
#140	EHF	14	13	27	1549.96
#141	MEIS1	14	13	27	7921.38
#142	ZNF274	14	10	24	1354.302
#143	ZNF135	14	8	22	176.534
#144	NR6A1	14	10	24	603.186
#145	MAFB	14	13	27	949.971
#146	SCAND2	13	10	23	684.838
#147	RAX	13	6	19	755.837
#148	VSX1	13	6	19	539.633
#149	PEG3	13	13	26	3742.766
#150	KDM5B	13	15	28	1195.32
#151	SOX4	13	13	26	1419.992
#152	SIX1	13	8	21	4950.873
#153	PLSCR1	13	9	22	820.152
#154	SOX9	13	11	24	718.53
#155	NR2F2	13	13	26	1423.219
#156	HIF1A	13	11	24	1281.647
#157	FOXF2	13	18	31	3047.536
#158	SNAI2	13	16	29	3763.167
#159	SOX1	13	9	22	1368.397
#160	MEOX2	12	12	24	350.043
#161	IRF8	12	9	21	704.226
#162	IKZF4	12	14	26	838.183
#163	CSDA	12	10	22	1525.229
#164	MYC	12	10	22	1088.183
#165	NFIA	12	9	21	7943.579
#166	TRERF1	12	15	27	1521.918
#167	PKNOX2	12	12	24	1558.324
#168	FOXQ1	12	11	23	1715.185
#169	KLF4	12	19	31	1642.921
#170	LMX1A	12	10	22	569.293
#171	HOXA6	12	15	27	1508.432
#172	NFATC1	12	9	21	2696.832
#173	EGR3	12	8	20	1453.719
#174	TCF12	12	14	26	1402.758
#175	TSC22D2	12	8	20	456.339
#176	ZNF71	11	12	23	317.838
#177	BACH2	11	12	23	433.556
#178	FOSL2	11	16	27	1364.943
#179	HHEX	11	12	23	8787.64
#180	ZNF83	11	14	25	2058.2
#181	FOXL1	11	13	24	642.354
#182	JUNB	11	9	20	719.644
#183	CNOT8	11	8	19	1996.674
#184	IRF9	11	11	22	1251.424
#185	TFAP2A	11	13	24	1574.675
#186	ZNF45	11	10	21	764.201
#187	RCOR2	11	10	21	542.241
#188	HNRNPK	11	9	20	3018.677
#189	E2F7	10	9	19	3090.724
#190	MYCL1	10	12	22	1202.543
#191	ZNF238	10	12	22	2014.616
#192	MSX2	10	9	19	1453.935
#193	LMX1B	10	12	22	939.956
#194	LZTS1	10	9	19	766.183
#195	STAT1	10	14	24	657.739
#196	ADNP	10	9	19	456.339
#197	NKX1-1	10	9	19	2466.588
#198	PITX1	10	9	19	2111.711
#199	HEYL	10	15	25	2742.515
#200	TAF1B	10	8	18	669.147
#201	ETV4	10	11	21	655.183
#202	FOXO3	10	12	22	1001.925
#203	GRHL2	10	12	22	1241.745
#204	FOXO1	10	15	25	2445.701
#205	GATA3	10	12	22	554.686
#206	CEBPE	10	9	19	364.155
#207	HOPX	10	17	27	2496.26
#208	NPAS1	10	13	23	4822.942
#209	MYOG	10	13	23	841.873
#210	MXD1	10	12	22	1891.13
#211	ISX	10	6	16	7628.48
#212	NFIX	10	13	23	2081.593
#213	GATA2	10	17	27	857.181
#214	SOX11	10	12	22	884.972
#215	ELF3	10	12	22	681.372
#216	GLI3	10	9	19	434.589
#217	HOXA10	9	11	20	729.728
#218	IRF7	9	15	24	1218.355
#219	ZFP36L2	9	15	24	469.29
#220	HMG20B	9	15	24	1424.897
#221	RB1	9	12	21	498.289
#222	HNF4A	9	7	16	5687.353
#223	ERF	9	12	21	1180.237
#224	CSRNP3	9	14	23	742.951
#225	TAL1	9	10	19	1639.141
#226	LHX5	9	6	15	177.036
#227	TLX2	9	12	21	872.375
#228	TBX10	9	13	22	1630.068
#229	MEIS2	9	12	21	871.244
#230	NR2F1	9	13	22	389.747
#231	ESRRG	9	14	23	20563.288
#232	TEAD1	9	14	23	981.95
#233	FOXM1	9	5	14	247.159
#234	ESR1	9	10	19	591.671
#235	ATF3	9	9	18	163.086
#236	HOXD8	9	12	21	3359.341
#237	NFYA	9	9	18	743.925
#238	NFATC4	9	11	20	608.321
#239	TEAD4	9	14	23	1936.616
#240	ZNF92	9	8	17	1615.52
#241	NR4A3	9	6	15	3843.126
#242	NFE2L2	9	11	20	810.8
#243	FOXN3	9	11	20	648.553
#244	ZNF33B	9	14	23	1749.652
#245	CREBL2	9	9	18	7473.848
#246	BCL6	9	15	24	2181.053
#247	PBX2	8	10	18	69.355
#248	SOX6	8	11	19	2023.332
#249	ZFHX4	8	10	18	400.645
#250	ZNF169	8	11	19	1747.126
#251	E2F1	8	17	25	2333.596
#252	ST18	8	6	14	753.68
#253	TSHZ1	8	17	25	951.385
#254	HOXA2	8	11	19	957.613
#255	CNBP	8	8	16	135.868
#256	ONECUT1	8	10	18	596.371
#257	MITF	8	18	26	1054.449
#258	POU2F3	8	12	20	1679.595
#259	STAT4	8	12	20	1230.945
#260	NR2C2	8	7	15	551.232
#261	BACH1	8	12	20	1286.128
#262	GLIS3	8	17	25	21705.088
#263	TSC22D3	8	13	21	468.594
#264	RAX2	7	13	20	771.413
#265	TBX2	7	11	18	771.695
#266	ZNF496	7	13	20	803.012
#267	TFCP2L1	7	14	21	1910.276
#268	TEF	7	10	17	286.471
#269	HIC1	7	17	24	819.014
#270	SOX17	7	13	20	3041.413
#271	PAX6	7	8	15	336.524
#272	ZEB1	7	15	22	313.286
#273	FOXA1	7	16	23	618.237
#274	MSX1	7	16	23	2985.176
#275	NFATC2	7	12	19	1139.426
#276	C5orf41	7	13	20	686.923
#277	NKX3-1	7	14	21	742.64
#278	ZRANB2	7	8	15	1829.808
#279	CREB1	7	11	18	198.33
#280	NFIB	7	13	20	1666.864
#281	SP140	7	10	17	354.638
#282	ZKSCAN5	7	10	17	327.402
#283	TCF15	7	10	17	304.023
#284	RARA	7	8	15	275.567
#285	MECOM	7	12	19	484.348
#286	TFAP4	7	11	18	490.819
#287	MAX	7	12	19	3205.04
#288	TFAM	7	9	16	1589.95
#289	NR2C1	7	12	19	335.7
#290	WNT5A	7	18	25	1302.815
#291	EGR2	7	11	18	197.009
#292	SIN3A	7	13	20	699.284
#293	C1orf85	7	14	21	915.228
#294	NKX2-3	7	17	24	5821.634
#295	HMGA2	7	15	22	1549.788
#296	HMG20A	7	13	20	475.791
#297	RORC	6	12	18	572.34
#298	MAFF	6	10	16	385.14
#299	BTG2	6	15	21	426.242
#300	KLF2	6	15	21	470.62
#301	GAS7	6	10	16	389.923
#302	ZNF367	6	15	21	661.948
#303	KLF9	6	11	17	5518.433
#304	PGR	6	12	18	1447.464
#305	HOXB6	6	11	17	475.688
#306	KLF6	6	13	19	3161.166
#307	NR3C1	6	13	19	491.544
#308	JUN	6	13	19	828.932
#309	SMAD5	6	8	14	981.007
#310	VAV1	6	8	14	237.458
#311	SLC30A9	6	16	22	1903.95
#312	ZNF85	6	15	21	389.088
#313	HOXC9	6	8	14	531.97
#314	SP3	6	8	14	124.066
#315	HOXD4	6	9	15	181.304
#316	NOBOX	6	10	16	269.667
#317	ELF1	6	12	18	271.96
#318	SOX10	6	10	16	288.9
#319	CITED1	6	10	16	325.835
#320	USF1	6	10	16	692.339
#321	TSC22D4	6	4	10	125.574
#322	DLX2	6	7	13	120.959
#323	SCAND1	6	8	14	274.867
#324	MEF2D	6	12	18	246.562
#325	TCF7L2	5	13	18	770.687
#326	TCFL5	5	14	19	1127.794
#327	ONECUT2	5	17	22	1678.051
#328	FOSB	5	15	20	1727.461
#329	C12orf28	5	5	10	6537.153
#330	SMAD1	5	5	10	210.419
#331	LCOR	5	11	16	3117.678
#332	ZNF207	5	7	12	948.055
#333	ZSCAN18	5	15	20	1298.761
#334	FUBP1	5	15	20	505.211
#335	GATA6	5	11	16	811.124
#336	HOXB5	5	8	13	474.279
#337	ALS2CR8	5	11	16	880.98
#338	ZSCAN2	5	10	15	91.261
#339	NR1H4	5	9	14	4297.424
#340	FOXF1	5	17	22	1347.478
#341	ZNF148	5	7	12	540.249
#342	ZFP90	5	13	18	1129.714
#343	MMP14	5	12	17	1430.332
#344	BCL3	5	13	18	390.032
#345	PURB	5	11	16	664.294
#346	CITED2	5	16	21	573.622
#347	CTNNB1	5	12	17	1422.203
#348	GLI2	5	12	17	208.371
#349	HR	4	15	19	6626.684
#350	GATAD1	4	8	12	565.121
#351	ARX	4	11	15	1092.084
#352	HLF	4	16	20	711.426
#353	HMGA1	4	14	18	324.855
#354	ZNF131	4	16	20	1532.296
#355	TFE3	4	13	17	269.937
#356	OVOL1	4	15	19	3174.558
#357	PPARG	4	13	17	225.991
#358	GATA5	4	10	14	1153.368
#359	MLL	4	13	17	1310.241
#360	EOMES	4	11	15	85.951
#361	ETV7	4	10	14	103.201
#362	NFAT5	4	10	14	1500.54
#363	MEF2A	4	15	19	282.643
#364	HOXC10	4	8	12	350.5
#365	TP63	4	10	14	6615.108
#366	FOSL1	4	9	13	3721.534
#367	MYT1	4	10	14	207.523
#368	IRF4	4	15	19	536.801
#369	SPEN	4	9	13	1512.095
#370	ZHX2	4	12	16	613.083
#371	TWIST2	4	16	20	506.409
#372	SCML1	4	12	16	1079.892
#373	ATF6B	4	12	16	119.295
#374	HEY1	4	11	15	3978.567
#375	NANOGNB	4	9	13	2881.404
#376	HOXA13	4	9	13	895.812
#377	TCF21	4	14	18	1676.168
#378	FOS	4	14	18	1004.678
#379	TGIF1	4	13	17	207.597
#380	TAF5L	4	9	13	363.617
#381	SIX4	4	14	18	412.183
#382	ZFP36L1	4	13	17	175.533
#383	ESRRB	4	10	14	100.211
#384	TRIM29	4	14	18	998.368
#385	ZSCAN10	4	10	14	692.97
#386	NR4A1	4	11	15	3577.412
#387	ZBTB38	4	12	16	902.704
#388	GABPB1	4	13	17	1421.532
#389	YBX1	3	9	12	809.326
#390	SPIB	3	13	16	718.322
#391	TP53	3	14	17	839.951
#392	ETV5	3	14	17	1324.968
#393	LMO4	3	11	14	646.446
#394	FOXD1	3	15	18	592.905
#395	FOXS1	3	13	16	683.183
#396	TSC22D1	3	13	16	77.464
#397	MLLT10	3	12	15	393.949
#398	PLAG1	3	19	22	286.18
#399	SPIC	3	11	14	2019.123
#400	NKX2-1	3	11	14	52.01
#401	HOXA1	3	13	16	2140.965
#402	NR1H3	3	11	14	681.837
#403	IRX2	3	18	21	12075.155
#404	FOXC1	3	13	16	345.047
#405	TAF5	3	12	15	466.362
#406	EGR1	3	17	20	1190.026
#407	ARNTL	3	10	13	195.83
#408	SIM2	3	13	16	7895.934
#409	ZNF167	3	12	15	4667.083
#410	PHTF1	3	16	19	169.652
#411	STRN3	3	11	14	95.982
#412	ZNF3	3	13	16	348.266
#413	NKX6-1	3	13	16	150.585
#414	POU6F1	3	10	13	2177.357
#415	ISL1	3	14	17	419.328
#416	ATF1	3	13	16	84.39
#417	PROX1	3	15	18	887.952
#418	HOXA9	3	11	14	662.264
#419	HMGB1	3	11	14	3044.811
#420	TEAD3	3	13	16	244.545
#421	ZNF189	3	8	11	110.606
#422	KDM5A	3	12	15	402.946
#423	CREB3L2	3	13	16	3539.49
#424	WT1	3	18	21	178.859
#425	HMBOX1	2	17	19	1448.262
#426	GTF2IRD1	2	15	17	92.04
#427	THRB	2	17	19	92.181
#428	FOXP2	2	10	12	319.357
#429	ZNF268	2	12	14	442.725
#430	ZNF165	2	15	17	122.145
#431	HES6	2	15	17	389.878
#432	NEUROD1	2	13	15	1184.542
#433	PRDM2	2	15	17	247.634
#434	CBFA2T2	2	12	14	549.196
#435	UHRF1	2	10	12	108.197
#436	POU2F2	2	8	10	246.167
#437	GABPA	2	10	12	47.924
#438	SMAD4	2	11	13	622.735
#439	PBX4	2	10	12	58.103
#440	TCF7L1	2	15	17	379.594
#441	VTN	2	10	12	129.546
#442	TBX1	2	8	10	28.881
#443	NR4A2	2	13	15	131.992
#444	KLF3	2	15	17	1119.432
#445	CEBPA	2	12	14	108.019
#446	ZNF117	2	18	20	191.731
#447	MEOX1	2	18	20	100.732
#448	GTF2H2	2	12	14	2459.48
#449	ZNF639	2	12	14	149.907
#450	FOXC2	2	15	17	299.371
#451	JUND	2	14	16	3248.412
#452	CEBPD	2	15	17	584.103
#453	ZSCAN16	2	15	17	188.688
#454	CTBP1	2	12	14	128.286
#455	ZFHX3	2	10	12	72.904
#456	CREB3L1	2	14	16	119.422
#457	HOXA5	2	15	17	116.977
#458	ZNF323	1	8	9	38.585
#459	ZNF70	1	12	13	53.982
#460	RBPJ	1	17	18	60.645
#461	NANOG	1	9	10	17.482
#462	SLC26A3	1	12	13	5673.515
#463	TCF3	1	13	14	34.377
#464	NFXL1	1	21	22	1875.92
#465	HAND1	1	8	9	148.666
#466	AFF4	1	9	10	24.461
#467	SCAND3	1	14	15	159.483
#468	ARNT2	1	14	15	4276.216
#469	RCAN1	1	15	16	64.059
#470	IRF5	1	18	19	89.666
#471	SOX7	1	12	13	158.953
#472	ZIC2	1	12	13	910.172
#473	TFAP2C	1	13	14	50.56
#474	BATF2	1	13	14	689.879
#475	CDKN2A	1	13	14	29.397
#476	NR1D2	1	15	16	287.732
#477	ZNF277	1	10	11	35.563
#478	NPAS2	1	11	12	28.849
#479	ELF5	1	14	15	108.325
#480	CREBZF	1	11	12	218.127
#481	HEY2	1	12	13	243.412
#482	YY1	1	12	13	51.537
#483	RORA	1	10	11	25.62
#484	ETV6	0	10	10	0
#485	SIX2	0	7	7	0
#486	IRX3	0	17	17	0
#487	TARDBP	0	10	10	0
#488	KLF10	0	17	17	0
#489	HIRA	0	6	6	0
#490	HES1	0	12	12	0
#491	SOX8	0	17	17	0
#492	CREB5	0	20	20	0
#493	SOX2	0	19	19	0
#494	ETV3	0	16	16	0
#495	SIM1	0	15	15	0
#496	TULP4	0	13	13	0
#497	SATB2	0	9	9	0
#498	HIF3A	0	14	14	0
#499	TFDP1	0	11	11	0
#500	ZNF232	0	10	10	0