Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZEB1	81	5	86	8375.974
#2	MEF2C	74	5	79	190.06
#3	ZFPM2	71	0	71	0
#4	CITED2	69	10	79	13883.75
#5	TCF4	61	5	66	230.064
#6	EBF1	56	6	62	546.968
#7	FOXP2	52	1	53	4.044
#8	MEOX2	50	4	54	347.15
#9	PEG3	46	8	54	404.427
#10	HOXA4	46	7	53	212.199
#11	E2F7	46	10	56	309.851
#12	MEIS1	45	7	52	372.349
#13	KLF5	44	5	49	1611.858
#14	FOXF1	43	6	49	293.092
#15	HNF4A	43	5	48	367.316
#16	CREB3L1	43	12	55	2687.319
#17	ISL1	42	6	48	142.838
#18	TFE3	41	6	47	251.451
#19	FOXA3	41	3	44	2493.5
#20	FOXM1	40	9	49	557.629
#21	C11orf9	40	7	47	137.421
#22	EHF	39	6	45	9309.171
#23	TWIST2	39	11	50	950.526
#24	BARX1	37	4	41	281.379
#25	ZNF165	37	13	50	1023.638
#26	ZNF41	36	11	47	3336.586
#27	HES6	36	12	48	1330.042
#28	CSRNP3	35	11	46	461.489
#29	PPARG	35	14	49	6839.021
#30	HLF	35	8	43	207.741
#31	NR2F1	34	11	45	282.449
#32	NR2F6	34	8	42	625.968
#33	MKX	34	10	44	3756.756
#34	HOXA2	34	6	40	74.518
#35	KLF1	33	19	52	7986.495
#36	HOXA5	33	10	43	113.919
#37	THRB	32	13	45	1351.275
#38	FOXK2	32	21	53	2207.007
#39	RARA	31	17	48	1429.336
#40	CEBPD	31	12	43	3303.169
#41	TEAD2	31	17	48	1725.603
#42	HNF4G	31	10	41	325.223
#43	ZNF238	31	17	48	3036.77
#44	SNAI2	31	10	41	809.616
#45	GAS7	30	8	38	1022.926
#46	PGBD1	30	12	42	3724.572
#47	SMAD2	30	19	49	2781.317
#48	ZNF174	30	10	40	1494.958
#49	HEY1	30	13	43	1621.397
#50	TEAD1	29	11	40	523.054
#51	HHEX	29	8	37	989.925
#52	MYBL2	29	10	39	388.719
#53	MNX1	29	12	41	2945.1
#54	ZFP36L2	29	11	40	1755.899
#55	ETV5	29	14	43	3952.556
#56	HNF1B	29	7	36	199.627
#57	OVOL1	29	13	42	1341.517
#58	PRRX1	28	6	34	184.01
#59	RUNX1T1	28	12	40	728.492
#60	CDX2	28	4	32	620.055
#61	FOXA2	28	14	42	698.715
#62	MMP14	28	13	41	619.234
#63	PBX1	28	17	45	20759.252
#64	MEOX1	27	8	35	88.637
#65	SMAD1	27	17	44	3943.882
#66	FOXO3	27	8	35	1350.19
#67	AHCTF1	27	12	39	822.966
#68	BTG2	27	11	38	1141.227
#69	ZNF397	27	16	43	675.559
#70	STRN3	27	11	38	1105.332
#71	HOXA10	26	5	31	248.609
#72	AEBP1	26	12	38	1394.328
#73	ARX	26	13	39	1852.051
#74	E2F5	26	11	37	565.075
#75	NKX2-3	26	13	39	1075.953
#76	IRF6	25	12	37	364.985
#77	HOXC12	25	16	41	3732.791
#78	GATA6	25	10	35	6508.348
#79	CBL	25	15	40	3363.481
#80	SOLH	25	17	42	546.992
#81	EGR2	25	11	36	419.103
#82	TAF13	25	15	40	1906.292
#83	RORC	25	11	36	1588.672
#84	SMAD9	24	11	35	374.115
#85	IRX3	24	15	39	815.713
#86	SOX9	24	10	34	227.616
#87	GRHL2	24	4	28	36.978
#88	KLF4	24	11	35	1545.219
#89	PROX1	23	17	40	1265.543
#90	TWIST1	23	7	30	240.097
#91	SPDEF	23	12	35	664.165
#92	HOXB7	23	10	33	1315.125
#93	SCAND1	23	19	42	5132.539
#94	CREB5	23	15	38	1181.211
#95	HOXB1	23	14	37	2530.513
#96	IRX5	22	11	33	1025.71
#97	NR1I2	22	13	35	750.461
#98	HOXC11	22	12	34	468.312
#99	BHLHE40	22	17	39	1546.289
#100	NFIB	22	10	32	542.464
#101	ZKSCAN3	22	12	34	2066.405
#102	SOX2	21	22	43	2352.479
#103	FOXQ1	21	13	34	390.49
#104	GATA4	21	11	32	5556.837
#105	GATA3	21	17	38	903.248
#106	HAND2	21	9	30	123.2
#107	ST18	21	7	28	890.997
#108	PKNOX2	21	7	28	851.872
#109	HOXD10	21	14	35	1143.292
#110	BACH2	21	13	34	2124.273
#111	FOXF2	20	12	32	289.196
#112	TCF21	20	12	32	628.89
#113	SOX1	20	15	35	1650.08
#114	FOXA1	20	19	39	295.038
#115	NR4A3	20	10	30	363.8
#116	VSX1	20	17	37	2057.059
#117	KLF12	20	15	35	239.425
#118	MTA2	20	18	38	13837.795
#119	TCF12	20	13	33	1210.557
#120	FOXK1	20	14	34	2337.495
#121	HOXA11	20	6	26	1027.584
#122	SPI1	20	14	34	672.802
#123	FOSL1	19	16	35	1443.034
#124	MYCN	19	17	36	1056.874
#125	CEBPA	19	14	33	2397.51
#126	NEUROD1	19	12	31	1437.586
#127	FOXN4	19	15	34	1968.122
#128	ZNF83	19	16	35	1271.518
#129	SP3	19	14	33	1020.314
#130	FOXD1	19	7	26	1967.502
#131	ZSCAN1	19	13	32	1407.696
#132	YY1	19	19	38	1862.942
#133	CCRN4L	18	15	33	10647.124
#134	NR4A2	18	7	25	341.73
#135	ARNT2	18	20	38	1519.419
#136	TCF3	18	14	32	1235.051
#137	STAT1	18	9	27	131.763
#138	KLF16	18	12	30	720.016
#139	HOXD11	18	16	34	1894.188
#140	NKX3-2	18	15	33	375.916
#141	SALL1	18	18	36	437.007
#142	SOX21	18	16	34	1898.714
#143	PHOX2B	18	16	34	938.6
#144	SOX5	18	14	32	447.158
#145	SOX10	18	12	30	317.515
#146	FOXN3	17	15	32	2101.342
#147	MSX2	17	14	31	780.55
#148	ONECUT2	17	9	26	684.27
#149	EN1	17	15	32	1303.009
#150	HOXB8	17	12	29	1061.948
#151	HOXA9	17	11	28	1032.818
#152	TFAP2C	17	22	39	1095.746
#153	TFCP2L1	17	16	33	355.342
#154	FOS	17	5	22	166.93
#155	PITX1	17	17	34	1113.423
#156	ZNF92	17	22	39	3027.982
#157	TFAP2A	17	11	28	321.059
#158	LHX2	17	18	35	1969.438
#159	SIX2	17	9	26	480.881
#160	ZNF135	17	10	27	150.801
#161	NPAS2	17	17	34	742.33
#162	TFDP3	17	20	37	2467.232
#163	ZFHX3	16	14	30	796.766
#164	HOXA13	16	9	25	247.363
#165	HOXB13	16	17	33	718.228
#166	FOSB	16	6	22	399.941
#167	ELF3	16	8	24	712.746
#168	MXD1	16	15	31	524.295
#169	SPIB	16	23	39	1416.782
#170	ZNF287	16	13	29	7663.836
#171	MYF5	16	14	30	3464.637
#172	NR4A1	16	5	21	437.622
#173	ARNT	16	14	30	1244.59
#174	HOXA7	16	17	33	1193.063
#175	NFATC4	16	9	25	118.101
#176	MAFK	16	11	27	621.867
#177	PKNOX1	16	17	33	1311.689
#178	TSHZ2	15	9	24	96.648
#179	ASCL1	15	3	18	120.82
#180	ESR1	15	16	31	888.912
#181	MEIS3	15	11	26	463.354
#182	TLX2	15	18	33	1369.361
#183	ETV4	15	12	27	136.629
#184	PAX4	15	13	28	852.319
#185	TFEC	15	23	38	1469.082
#186	ZNF93	15	20	35	1311.467
#187	TCF20	15	18	33	1290.439
#188	TBX2	15	14	29	228.638
#189	FOXJ1	15	16	31	637.914
#190	MESP1	14	21	35	1905.652
#191	SIX6	14	19	33	5793.522
#192	HEY2	14	13	27	1043.951
#193	NFATC1	14	11	25	516.679
#194	ZSCAN18	14	14	28	1331.933
#195	SOX13	14	15	29	1314.175
#196	SCRT1	14	17	31	740.154
#197	SREBF1	14	14	28	417.324
#198	MYT1	14	12	26	1232.922
#199	MESP2	14	17	31	841.406
#200	TBX3	14	21	35	1016.734
#201	EGR3	14	7	21	156.342
#202	ASCL2	14	11	25	376.317
#203	ESR2	14	16	30	1580.391
#204	WNT5A	14	18	32	1202.952
#205	SIM2	14	17	31	2599.439
#206	IKZF1	14	12	26	553.045
#207	JUND	14	19	33	1170.121
#208	E2F8	14	14	28	155.452
#209	HOXC5	14	17	31	997.965
#210	SLC26A3	14	9	23	385.78
#211	SCAND3	14	22	36	1248.179
#212	ATF6B	14	12	26	671.564
#213	POU4F2	14	17	31	743.534
#214	ISL2	13	13	26	141.893
#215	SOX15	13	8	21	1467.69
#216	ETV6	13	18	31	406.088
#217	CDKN2A	13	18	31	848.681
#218	TP73	13	15	28	692.924
#219	RXRB	13	15	28	2520.719
#220	DLX6	13	28	41	2923.684
#221	ZNF639	13	14	27	1092.749
#222	KLF17	13	17	30	980.924
#223	SOX11	13	14	27	468.938
#224	RERE	13	23	36	2124.609
#225	ESRRG	13	17	30	650.533
#226	TULP4	13	14	27	819.352
#227	ZNF117	13	18	31	1809.86
#228	TBX5	13	17	30	1133.789
#229	ZEB2	13	10	23	139.885
#230	ZFHX4	13	11	24	528.796
#231	RUNX2	12	14	26	925.258
#232	ERF	12	16	28	1614.542
#233	ZIC2	12	15	27	574.593
#234	SPIC	12	22	34	1406.005
#235	ELK1	12	21	33	1297.078
#236	MIXL1	12	14	26	1337.253
#237	ALS2CR8	12	18	30	476.317
#238	GLI3	12	15	27	488.919
#239	KDM5B	12	16	28	1874.013
#240	IRX4	12	13	25	1548.325
#241	ZNF256	12	18	30	4649.98
#242	HMX2	12	21	33	2225.772
#243	TBR1	12	13	25	737.989
#244	POU3F4	12	16	28	1234.26
#245	VENTX	12	19	31	1419.062
#246	POU2F3	12	16	28	652.51
#247	FOXE1	12	22	34	828.203
#248	NPAT	12	14	26	1907.931
#249	FUBP1	12	15	27	1489.223
#250	HOXD13	12	16	28	901.649
#251	ZIC3	12	15	27	1614.662
#252	HOXC13	12	16	28	999.134
#253	GLI2	12	19	31	3281.83
#254	ZXDC	12	25	37	1873.925
#255	HR	12	17	29	1056.24
#256	BCL11B	12	20	32	1439.864
#257	FOXB1	12	18	30	1453.318
#258	POU3F1	12	17	29	1323.228
#259	PPARD	12	17	29	719.245
#260	SIX1	12	18	30	767.115
#261	MLXIPL	12	15	27	332.9
#262	RFX3	12	22	34	4224.573
#263	POU4F1	11	11	22	488.092
#264	NEUROD2	11	17	28	1021.884
#265	HOXB6	11	13	24	653.198
#266	E2F2	11	18	29	712.512
#267	TRIM29	11	19	30	724.567
#268	NKX2-8	11	15	26	1692.953
#269	WT1	11	20	31	988.188
#270	ZNF131	11	19	30	666.487
#271	FOXG1	11	13	24	747.047
#272	ZSCAN2	11	16	27	1106.709
#273	FOXH1	11	19	30	726.579
#274	ISX	11	8	19	819.906
#275	ZHX2	11	19	30	2142.688
#276	HMGA2	11	17	28	1357.887
#277	MYCL1	11	16	27	524.248
#278	NR6A1	11	11	22	458.951
#279	THRA	11	12	23	201.47
#280	STAT2	11	18	29	583.532
#281	ELK4	11	16	27	509.581
#282	HOXC9	11	12	23	236.385
#283	NFYC	11	17	28	1185.469
#284	DLX3	11	12	23	971.344
#285	HESX1	11	19	30	875.851
#286	RXRG	11	16	27	1129.847
#287	ELF5	11	18	29	956.719
#288	LHX4	11	22	33	1343.305
#289	DMRT1	11	15	26	2272.948
#290	NKX2-1	11	17	28	948.564
#291	GLIS3	11	24	35	1645.45
#292	ZNF167	11	21	32	670.843
#293	PBX3	11	14	25	1005.825
#294	ALX1	11	17	28	1052.457
#295	SOX12	11	16	27	382.09
#296	DMBX1	11	15	26	839.26
#297	SMAD3	11	17	28	536.099
#298	PRRX2	10	15	25	700.74
#299	NR5A1	10	17	27	747.168
#300	C12orf28	10	15	25	476.814
#301	RORA	10	19	29	1040.725
#302	DMRT2	10	17	27	1639.52
#303	SIX3	10	16	26	1518.475
#304	MZF1	10	24	34	2067.167
#305	HOPX	10	17	27	864.882
#306	USF1	10	9	19	308.921
#307	ZNF80	10	17	27	1985.175
#308	TBX20	10	13	23	982.992
#309	POU3F2	10	18	28	671.052
#310	SLC2A4RG	10	19	29	1796.943
#311	HOXC10	10	11	21	251.94
#312	GRHL3	10	19	29	1150.022
#313	HOXD4	10	14	24	509.079
#314	ZNF483	10	18	28	758.268
#315	NCOR1	10	15	25	709.256
#316	TFAP2B	10	13	23	914.603
#317	HOXA1	10	18	28	1759.361
#318	SATB2	10	12	22	328.991
#319	ZIC5	10	16	26	818.137
#320	CUX2	10	19	29	874.306
#321	ARNTL2	10	15	25	567.058
#322	STAT5B	10	9	19	65.591
#323	ZFP42	10	16	26	1520.32
#324	VTN	10	17	27	849.624
#325	BNC1	10	19	29	612.923
#326	ESRRB	10	15	25	1251.246
#327	HCFC1	10	21	31	668.838
#328	NKX2-5	10	11	21	841.453
#329	FOXL2	10	18	28	1125.431
#330	IRX2	10	21	31	698.524
#331	ZNF496	10	18	28	1168.087
#332	KCNH8	10	18	28	852.219
#333	SCAND2	10	19	29	1266.767
#334	MYNN	10	27	37	1754.711
#335	TSC22D3	10	22	32	1140.923
#336	MECOM	10	24	34	1312.419
#337	HOXD9	9	18	27	513.865
#338	SIX4	9	21	30	1298.068
#339	TLX3	9	18	27	1865.938
#340	FOXP1	9	14	23	750.118
#341	NPAS1	9	19	28	1101.098
#342	ZSCAN20	9	19	28	897.033
#343	EGR4	9	16	25	306.339
#344	BLZF1	9	21	30	640.786
#345	ATF2	9	23	32	1501.604
#346	ESX1	9	22	31	1167.316
#347	TSC22D2	9	15	24	685.188
#348	LHX8	9	22	31	916.265
#349	RUNX3	9	20	29	3554.802
#350	SOX8	9	24	33	915.218
#351	NFIA	9	20	29	2888.568
#352	TFAP4	9	20	29	1494.067
#353	ATOH1	9	18	27	853.224
#354	ZNF154	9	7	16	675.152
#355	POU2F2	9	18	27	1555.257
#356	PLSCR1	9	24	33	900.169
#357	NKX6-2	9	23	32	1208.44
#358	ZNF3	8	17	25	832.77
#359	ZSCAN12	8	15	23	700.99
#360	AFF4	8	18	26	1717.444
#361	MLL	8	18	26	806.748
#362	HNRNPAB	8	21	29	1246.146
#363	LMX1A	8	21	29	684.768
#364	LASS5	8	21	29	831.421
#365	GCM1	8	14	22	598.567
#366	HOXD1	8	18	26	880.558
#367	FEV	8	10	18	373.44
#368	FOXP3	8	14	22	1464.769
#369	NR2E3	8	17	25	1626.732
#370	IKZF3	8	23	31	1908.186
#371	BHLHE41	8	17	25	343.603
#372	POU6F2	8	10	18	280.055
#373	ZNF81	8	18	26	546.012
#374	KLF2	8	21	29	663.024
#375	REST	8	23	31	1246.147
#376	GATA5	8	18	26	651.423
#377	TADA3	8	17	25	707.723
#378	NANOG	8	17	25	490.976
#379	NR1I3	8	17	25	747.824
#380	NFKB2	8	16	24	861.62
#381	SOX6	8	19	27	1033.223
#382	NRL	8	15	23	398.23
#383	HOXD3	8	23	31	1117.817
#384	GSX1	8	22	30	1417.202
#385	PGR	8	20	28	670.338
#386	CTBP1	8	14	22	710.258
#387	HNF1A	8	13	21	110.644
#388	TADA2A	8	18	26	764.355
#389	NR5A2	8	17	25	933.918
#390	HIC1	8	6	14	92.207
#391	FOXC2	8	16	24	636.089
#392	HMGB2	8	17	25	635.763
#393	NR2E1	8	16	24	507.319
#394	LEF1	8	22	30	626.657
#395	TFAP2D	8	19	27	599.782
#396	SNAI3	8	21	29	1315.94
#397	POU3F3	8	17	25	546.06
#398	FOXE3	7	10	17	783.67
#399	NR0B1	7	16	23	735.538
#400	SIN3A	7	18	25	524.332
#401	FOXC1	7	20	27	422.131
#402	TLX1	7	20	27	840.585
#403	TBX15	7	21	28	943.585
#404	ZSCAN4	7	21	28	690.229
#405	KLF9	7	11	18	79.072
#406	DLX2	7	14	21	299.85
#407	RORB	7	11	18	361.873
#408	EMX1	7	18	25	384.547
#409	PITX2	7	22	29	1429.835
#410	LHX9	7	23	30	1143.676
#411	PRDM2	7	20	27	663.791
#412	TEF	7	18	25	181.436
#413	CITED1	7	16	23	577.815
#414	RCAN1	7	14	21	1544.279
#415	PAX8	7	18	25	498.714
#416	CSDA	7	27	34	614.227
#417	ZIC1	7	13	20	801.653
#418	RFXAP	7	16	23	457.538
#419	CREM	7	11	18	144.431
#420	NFE2	7	22	29	1968.518
#421	SOX30	7	18	25	1871.364
#422	RCOR1	7	17	24	1019.349
#423	TAL1	7	13	20	275.993
#424	FOXR2	7	18	25	1092.922
#425	OLIG2	6	12	18	733.837
#426	NFATC2	6	20	26	597.026
#427	FOXD2	6	13	19	320.44
#428	SMAD6	6	17	23	793.849
#429	POU1F1	6	20	26	669.232
#430	DLX1	6	17	23	161.558
#431	HIRA	6	19	25	549.043
#432	POU5F2	6	25	31	662.854
#433	HIF3A	6	15	21	122.116
#434	TBX1	6	20	26	732.979
#435	MITF	6	22	28	777.247
#436	MAF	6	19	25	611.606
#437	ETV1	6	22	28	645.49
#438	CREBBP	6	19	25	548.193
#439	GSC2	6	17	23	546.208
#440	PAX6	6	18	24	400.796
#441	ZFP36L1	6	20	26	4017.916
#442	PPARA	6	13	19	361.31
#443	ZNF90	6	18	24	369.994
#444	PDX1	6	16	22	724.431
#445	ZNF175	6	18	24	651.108
#446	FOXL1	6	19	25	500.441
#447	CRX	6	18	24	582.091
#448	EN2	6	17	23	344.5
#449	MYT1L	6	22	28	1079.604
#450	TAF4	6	16	22	683.911
#451	POU2F1	6	14	20	483.173
#452	HSF5	6	19	25	677.237
#453	BRD8	6	18	24	717.912
#454	HMG20B	6	16	22	270.445
#455	TBX6	6	19	25	460.531
#456	ANKRD30A	6	22	28	811.73
#457	MLLT10	6	17	23	415.919
#458	FOXD3	6	15	21	112.298
#459	PAX7	5	15	20	509.865
#460	CREBZF	5	19	24	632.852
#461	PAX3	5	25	30	653.396
#462	MGA	5	19	24	659.81
#463	OTX1	5	14	19	343.011
#464	CREB3L3	5	16	21	846.612
#465	LZTS1	5	16	21	306.718
#466	FOXI1	5	15	20	406.676
#467	FOXO1	5	20	25	592.508
#468	NR1H4	5	13	18	183.138
#469	IRX1	5	19	24	721.645
#470	C2orf3	5	19	24	514.027
#471	ONECUT1	5	17	22	495.645
#472	ZNF215	5	21	26	445.5
#473	IRF4	5	19	24	540.658
#474	LHX1	5	17	22	607.704
#475	ZSCAN10	5	17	22	508.233
#476	ZSCAN23	5	16	21	644.727
#477	ZNF85	5	24	29	674.178
#478	NFIX	5	20	25	938.627
#479	RARG	5	23	28	600.531
#480	TP63	4	20	24	477.539
#481	EPAS1	4	16	20	434.349
#482	SOX4	4	15	19	649.93
#483	SNAPC5	4	19	23	319.438
#484	HES5	4	15	19	252.435
#485	NFYA	4	20	24	330.519
#486	GATAD1	4	22	26	501.542
#487	RUNX1	4	23	27	437.678
#488	VDR	4	21	25	537.09
#489	FLI1	4	18	22	309.504
#490	ZNF71	3	14	17	75.498
#491	ZNF396	3	20	23	243.721
#492	SMAD4	3	22	25	506.118
#493	SIM1	3	21	24	516.434
#494	OTX2	3	23	26	792.485
#495	RARB	3	24	27	601.945
#496	NKX6-1	2	16	18	178.439
#497	ZNF157	2	23	25	271.358
#498	SP140	2	21	23	241.071
#499	TBX22	2	24	26	257.13
#500	PTH	1	25	26	88.156