Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	RAX	41	7	48	13943.957
#2	CNBP	40	3	43	372.51
#3	POU5F1B	39	3	42	484.097
#4	SP3	39	5	44	1210.4
#5	HNF1B	38	8	46	1854.69
#6	HMX1	37	3	40	60.579
#7	PITX3	34	2	36	65.734
#8	GBX1	33	3	36	63.737
#9	CITED2	33	10	43	2123.298
#10	HOXB1	33	5	38	730.409
#11	FOXM1	33	4	37	1504.966
#12	TRIM28	33	9	42	3135.114
#13	MEF2C	32	4	36	633.011
#14	IRF8	32	3	35	206.768
#15	ELK3	32	13	45	1457.154
#16	IRF6	31	7	38	1152.451
#17	FLI1	31	2	33	394.552
#18	CCRN4L	31	7	38	286.594
#19	FOXO4	30	5	35	1163.015
#20	EPAS1	29	6	35	1828.918
#21	BACH1	29	10	39	908.964
#22	MYBL2	28	8	36	1666.219
#23	ZFPM2	28	6	34	893.08
#24	EVX1	28	6	34	324.947
#25	TAF7	28	11	39	7766.093
#26	YY1	28	12	40	3137.567
#27	NKX2-1	28	7	35	1084.776
#28	TRIM29	27	4	31	377.12
#29	FOXF1	27	5	32	2662.169
#30	TARDBP	27	4	31	789.573
#31	ZEB1	27	12	39	1253.405
#32	E2F4	27	4	31	969.129
#33	TP63	27	4	31	297.944
#34	ZEB2	27	6	33	930.386
#35	HNRNPK	27	4	31	306.152
#36	HOPX	27	11	38	1054.953
#37	CREB3L2	27	15	42	2400.627
#38	NFKB2	27	7	34	1710.403
#39	SOX2	27	10	37	1243.179
#40	HDAC2	26	9	35	593.86
#41	KLF5	26	11	37	2143.84
#42	UBP1	26	8	34	15393.658
#43	CNOT8	26	12	38	1275.657
#44	ELF2	26	8	34	1513.373
#45	ARNTL2	25	9	34	1749.593
#46	FUBP1	25	10	35	2799.042
#47	FOXG1	25	8	33	2266.06
#48	KLF2	25	8	33	641.102
#49	HOXD9	25	9	34	447.506
#50	ATF1	25	6	31	441.078
#51	KLF10	25	13	38	1303.844
#52	E2F6	25	10	35	789.082
#53	HSF4	24	7	31	519.195
#54	CBFB	24	8	32	752.469
#55	RARG	24	7	31	1587.526
#56	GAS7	24	7	31	1388.31
#57	RUNX3	24	11	35	3149.426
#58	NFE2L2	24	8	32	1101.299
#59	TEAD4	24	4	28	1800.293
#60	ZFP36L2	24	13	37	1504.323
#61	CREBL2	23	7	30	1780.391
#62	NR1I2	23	5	28	540.876
#63	FOXP3	23	7	30	1577.323
#64	RERE	23	16	39	3933.607
#65	MLXIPL	23	7	30	1726.541
#66	PTTG1	23	6	29	405.707
#67	TCF15	23	5	28	324.774
#68	VAV1	23	8	31	1368.517
#69	PA2G4	22	13	35	1969.657
#70	SOX15	22	6	28	381.095
#71	HAND2	22	7	29	729.937
#72	NR3C1	22	8	30	1111.665
#73	MAX	22	7	29	547.759
#74	TFE3	22	10	32	1846.024
#75	CSDA	21	16	37	2834.734
#76	TCF4	21	20	41	1690.669
#77	CEBPB	21	11	32	1797.013
#78	TP73	21	9	30	17225.907
#79	TCF7L2	21	11	32	1203.269
#80	KDM5B	21	13	34	357.102
#81	BNC1	21	6	27	1112.24
#82	TCF21	21	9	30	1087.794
#83	TSC22D4	20	5	25	136.826
#84	NR2E3	20	11	31	396.195
#85	RELA	20	12	32	3033.935
#86	TCF12	20	11	31	4573.113
#87	MGA	20	12	32	1057.034
#88	SMAD6	20	8	28	503.16
#89	DMTF1	20	8	28	705.193
#90	LASS6	20	10	30	1853.312
#91	ELF1	20	14	34	2880.132
#92	ATF2	20	7	27	465.988
#93	PAX8	19	8	27	607.967
#94	NR2F2	19	11	30	1636.074
#95	PURA	19	11	30	983.289
#96	SLC30A9	19	8	27	422.166
#97	RELB	19	11	30	969.226
#98	MYT1	19	5	24	61.434
#99	ZFP36L1	19	10	29	2144.541
#100	CBFA2T2	19	7	26	5241.94
#101	PITX1	19	10	29	743.539
#102	AEBP1	19	7	26	776.769
#103	ETV7	19	11	30	341.932
#104	ADNP	19	12	31	1821.381
#105	FOXE1	18	13	31	2803.995
#106	HIF1A	18	18	36	2191.966
#107	MBD1	18	9	27	1398.661
#108	SOX17	18	10	28	2039.826
#109	NFYB	18	9	27	633.835
#110	TFAP2A	18	10	28	772.771
#111	HOXD10	18	10	28	3342.966
#112	LHX5	18	6	24	887.416
#113	HMGB1	18	15	33	2323.086
#114	IRF2	18	10	28	738.371
#115	LHX3	18	8	26	189.616
#116	MYOG	17	6	23	185.02
#117	KLF15	17	9	26	2179.559
#118	RARA	17	16	33	1002.494
#119	GATAD2A	17	11	28	1968.026
#120	LZTS1	17	12	29	2337.408
#121	SP140	17	7	24	704.709
#122	JUNB	17	9	26	1812.183
#123	CREBBP	17	9	26	496.993
#124	USF2	17	9	26	9313.397
#125	TBX3	17	14	31	1851.735
#126	RBPJ	17	10	27	9673.168
#127	LMO4	17	14	31	1681.013
#128	VENTX	17	7	24	531.398
#129	HOXC4	16	10	26	2245.852
#130	SIX5	16	12	28	250.419
#131	FOSL2	16	12	28	1028.655
#132	GATA6	16	10	26	1422.721
#133	TSC22D2	16	14	30	1026.302
#134	ZNF277	16	11	27	2717.513
#135	AFF1	16	15	31	3288.781
#136	NR5A1	16	11	27	282.008
#137	TRIM22	16	15	31	2170.766
#138	MYC	16	17	33	1960.258
#139	MAFF	16	14	30	532.176
#140	STRN3	16	14	30	1013.731
#141	BTAF1	16	11	27	541.894
#142	RB1	16	13	29	1100.603
#143	ATOH1	16	6	22	137.076
#144	BCL6	15	11	26	3064.955
#145	FOXJ1	15	11	26	684.516
#146	ELK1	15	5	20	794.027
#147	HMGA1	15	10	25	1060.223
#148	TCF3	15	12	27	891.687
#149	ZNF24	15	11	26	1121.831
#150	SOX21	15	6	21	176.743
#151	DLX2	15	9	24	2272.244
#152	TSHZ2	15	6	21	250.267
#153	TFCP2	15	13	28	1283.106
#154	HMGB2	15	14	29	828.15
#155	ASCL1	15	8	23	7186.238
#156	GABPB1	15	13	28	1862.014
#157	GTF2IRD1	15	14	29	1854.464
#158	HOXC8	15	10	25	2438.986
#159	NR2C1	15	13	28	1394.377
#160	RFXANK	15	14	29	1495.648
#161	SPDEF	15	14	29	3069.446
#162	FOXD1	15	13	28	774.172
#163	STAT5B	15	12	27	1330.352
#164	TAF10	14	16	30	2907.503
#165	HCFC1	14	14	28	770.741
#166	KLF7	14	14	28	1760.473
#167	FOXA2	14	14	28	4640.128
#168	POU2F2	14	7	21	859.429
#169	HMG20A	14	13	27	1553.987
#170	MITF	14	12	26	767.412
#171	SMAD2	14	11	25	145.03
#172	HIF3A	14	9	23	1199.97
#173	MNX1	14	9	23	405.527
#174	PCGF2	14	11	25	199.597
#175	SNAI2	14	13	27	1526.139
#176	ZNF207	14	8	22	275.053
#177	FOSB	14	9	23	865.877
#178	SCAND1	14	16	30	2117.219
#179	CREM	14	12	26	2263.259
#180	SREBF2	13	14	27	631.03
#181	NFIL3	13	12	25	1069.072
#182	JUN	13	15	28	2863.725
#183	PKNOX2	13	15	28	1154.101
#184	CREBZF	13	15	28	2115.645
#185	ZNF148	13	11	24	1245.859
#186	TFEB	13	16	29	1276.805
#187	SPEN	13	8	21	430.403
#188	HCLS1	13	12	25	971.091
#189	RXRA	13	15	28	1618.458
#190	RORC	13	9	22	321.992
#191	TFDP2	13	11	24	474.006
#192	CNOT7	13	9	22	799.097
#193	TAF5	13	14	27	847.332
#194	NPAS1	13	9	22	772.797
#195	SNAPC2	13	8	21	388.646
#196	ZNF236	13	5	18	171.223
#197	EN1	13	13	26	4246.494
#198	LASS2	13	12	25	1549.104
#199	VDR	13	16	29	1514.079
#200	AHR	13	15	28	5084.133
#201	IKZF1	13	14	27	2048.939
#202	CREB1	13	9	22	2777.182
#203	NFAT5	13	7	20	680.584
#204	NR3C2	12	12	24	5616.712
#205	FOS	12	14	26	2818.157
#206	MAFB	12	13	25	1921.237
#207	SOX4	12	13	25	804.605
#208	RCOR1	12	11	23	6546.255
#209	TCF7	12	11	23	980.695
#210	RUNX1T1	12	11	23	1146.169
#211	NFATC1	12	12	24	764.44
#212	ERF	12	10	22	662.583
#213	TCF20	12	13	25	1127.445
#214	MEOX2	12	7	19	298.687
#215	ETV4	12	15	27	3473.132
#216	NKX2-5	12	13	25	884.769
#217	KLF3	12	16	28	2067.863
#218	TAF4	12	13	25	1541.217
#219	SOX10	12	12	24	3434.382
#220	MLLT10	12	10	22	259.404
#221	PHF1	12	14	26	1209.471
#222	ZNF446	12	8	20	257.849
#223	SIX3	12	16	28	3027.775
#224	ZGPAT	11	12	23	716.887
#225	SOX13	11	19	30	1428.837
#226	RUNX1	11	15	26	1673.519
#227	ZBTB38	11	18	29	2541.368
#228	TCF7L1	11	18	29	1231.303
#229	STAT3	11	11	22	892.928
#230	MAFG	11	13	24	1005.415
#231	MYCN	11	12	23	3594.13
#232	ENO1	11	15	26	3457.837
#233	STAT1	11	15	26	1075.568
#234	MYCL1	11	14	25	2153.682
#235	PRRX2	11	15	26	1561.96
#236	MMP14	11	15	26	1871.21
#237	TBX4	11	13	24	665.969
#238	EGR2	11	11	22	1815.391
#239	E2F5	11	14	25	2259.158
#240	FOXN3	11	12	23	9676.873
#241	E2F3	11	10	21	2497.971
#242	TSC22D3	11	17	28	976.532
#243	FOXH1	11	10	21	203.807
#244	MEF2A	11	15	26	1892.196
#245	FOXI1	11	11	22	1608.167
#246	KLF11	11	14	25	627.905
#247	NOTCH1	11	11	22	1273.45
#248	HR	11	18	29	3939.222
#249	ECSIT	10	13	23	374.889
#250	FOXK2	10	16	26	1852.484
#251	SLC2A4RG	10	18	28	1315.084
#252	SNAPC5	10	19	29	1868.507
#253	FOXO3	10	9	19	1203.074
#254	FOXJ3	10	12	22	1291.312
#255	ZKSCAN1	10	13	23	374.277
#256	CTCF	10	8	18	456.385
#257	GRHL2	10	13	23	689.951
#258	IRF9	10	11	21	683.734
#259	MEIS3P1	10	16	26	886.509
#260	TCFL5	10	12	22	555.455
#261	GTF2H3	10	7	17	1331.805
#262	EDF1	10	15	25	1392.787
#263	REST	10	10	20	1243.002
#264	HOXB13	10	13	23	1200.519
#265	BHLHE41	10	14	24	850.035
#266	HOXD11	10	7	17	1217.219
#267	HOXC11	10	9	19	1611.293
#268	HOXB5	10	11	21	1708.509
#269	CTBP1	10	14	24	1165.442
#270	BHLHE40	10	12	22	849.172
#271	SIX2	10	11	21	750.107
#272	ETV1	10	17	27	1163.473
#273	SOX18	10	13	23	1578.776
#274	EGR4	10	10	20	536.672
#275	XBP1	10	13	23	1176.459
#276	NKX2-8	10	5	15	430.372
#277	NFKB1	10	13	23	1239.202
#278	ZNF238	10	16	26	1806.444
#279	ZNF174	10	12	22	783.677
#280	NFYC	10	9	19	1311.188
#281	PAX6	9	17	26	2575.613
#282	IRF4	9	11	20	573.32
#283	ZNF93	9	12	21	1183.767
#284	ZNF83	9	11	20	763.085
#285	TGIF1	9	18	27	2438.781
#286	HSF1	9	14	23	1844.597
#287	PBX1	9	13	22	594.806
#288	ZNF131	9	14	23	1675.108
#289	BATF	9	11	20	1167.398
#290	IRF3	9	15	24	857.185
#291	IRF1	9	15	24	933.664
#292	MYNN	9	10	19	1011.576
#293	SOX12	9	13	22	1179.338
#294	TULP4	9	11	20	7439.767
#295	HNRNPAB	9	13	22	1480.235
#296	ESRRA	9	6	15	56.201
#297	NFE2L1	9	16	25	1553.507
#298	PLAGL2	9	21	30	2469.178
#299	GCFC1	9	9	18	1938.276
#300	CREB3	9	20	29	4841.866
#301	ZBTB48	9	13	22	2409.786
#302	MLL	9	15	24	1069.473
#303	NFIC	9	18	27	873.28
#304	MEIS1	9	15	24	953.364
#305	STAT6	9	14	23	893.774
#306	PRDM1	8	9	17	553.829
#307	GLI2	8	8	16	313.783
#308	MAF	8	8	16	173.061
#309	ZHX2	8	17	25	2083.584
#310	DLX4	8	13	21	688.384
#311	HIC1	8	10	18	232.28
#312	HES1	8	15	23	1270.632
#313	ATF5	8	18	26	1527.683
#314	MTA1	8	17	25	2734.608
#315	CREB3L1	8	12	20	926.4
#316	SATB1	8	12	20	699.033
#317	SMAD4	8	11	19	827.399
#318	PPARD	8	7	15	743.395
#319	MECOM	8	22	30	1672.022
#320	NCOR1	8	11	19	159.449
#321	YBX1	8	22	30	2460.608
#322	ZNF274	8	7	15	451.222
#323	PLAG1	8	14	22	966.201
#324	HDAC1	8	16	24	3323.66
#325	LHX2	8	14	22	1211.566
#326	GATAD1	8	17	25	1575.262
#327	SOX9	8	17	25	900.218
#328	ATF4	8	12	20	791.258
#329	ZNF217	8	14	22	374.361
#330	WNT5A	8	16	24	990.015
#331	TFAM	8	21	29	1042.209
#332	GATA2	8	11	19	974.14
#333	HOXB7	8	19	27	792.009
#334	TWIST1	8	16	24	907.795
#335	BCL11B	8	14	22	875.311
#336	SOLH	8	14	22	1494.397
#337	FOSL1	8	13	21	1206.191
#338	GATA1	8	12	20	172.843
#339	KDM5A	8	15	23	797.034
#340	ZNF45	8	14	22	937.464
#341	HOXA10	8	18	26	4124.003
#342	SMAD3	8	13	21	477.477
#343	PRRX1	7	16	23	1137.808
#344	NR2F1	7	19	26	1604.549
#345	FOXO1	7	17	24	1130.252
#346	SPIB	7	13	20	5213.297
#347	SIX1	7	12	19	458.356
#348	YEATS4	7	14	21	1683.635
#349	BUD31	7	14	21	484.05
#350	GLI3	7	12	19	538.816
#351	ZNF281	7	15	22	799.729
#352	IRF7	7	20	27	775.776
#353	CLOCK	7	17	24	743.534
#354	BTG2	7	25	32	1256.795
#355	MTA2	7	14	21	1052.906
#356	NPAS2	7	14	21	635.918
#357	NR4A1	7	7	14	258.525
#358	SCAND2	7	11	18	376.975
#359	SALL2	7	17	24	933.408
#360	FBXW7	7	19	26	2192.823
#361	KLF6	7	18	25	535.658
#362	TFAP2B	7	9	16	412.432
#363	KLF9	7	17	24	1315.422
#364	BCL3	6	24	30	1244.304
#365	NOLC1	6	17	23	781.231
#366	ELF4	6	15	21	375.179
#367	BRD8	6	14	20	957.243
#368	UBN1	6	14	20	774.728
#369	SPI1	6	13	19	934.732
#370	ETV6	6	15	21	1062.474
#371	CUX1	6	13	19	628.784
#372	NR1H2	6	16	22	1221.792
#373	NKX3-1	6	11	17	871.292
#374	NFATC3	6	13	19	1633.751
#375	IRF5	6	17	23	576.575
#376	DRAP1	6	15	21	696.912
#377	BACH2	6	7	13	319.172
#378	DDIT3	6	10	16	723.602
#379	TSC22D1	6	15	21	739.818
#380	LEF1	6	12	18	1223.291
#381	HHEX	6	19	25	1237.968
#382	STAT4	6	14	20	1722.955
#383	TBX2	6	12	18	440.301
#384	SUPT6H	6	17	23	1381.076
#385	HOXB6	6	11	17	363.618
#386	TP53	6	19	25	2408.587
#387	NR4A2	6	11	17	481.912
#388	NR1D2	6	11	17	435.855
#389	ATF3	6	13	19	1310.678
#390	ZNF219	6	9	15	200.974
#391	NR1H3	6	9	15	893.437
#392	PROX1	6	15	21	886.627
#393	MEF2D	6	10	16	1441.553
#394	FOXL2	5	17	22	1175.253
#395	PHTF1	5	12	17	1385.871
#396	TRPS1	5	13	18	503.777
#397	GTF2H4	5	16	21	966.717
#398	IRX5	5	13	18	302.652
#399	EGR1	5	9	14	512.246
#400	ZNF133	5	11	16	529.682
#401	PRDM2	5	10	15	730.341
#402	AATF	5	14	19	440.051
#403	HOXA1	5	15	20	765.802
#404	ETV5	5	22	27	2038.908
#405	TFDP1	5	21	26	496.14
#406	ZNF232	5	15	20	483.434
#407	TAF6	5	13	18	622.531
#408	CTNNB1	5	14	19	896.892
#409	REL	5	18	23	2312.72
#410	MSRB2	5	13	18	329.896
#411	SOX11	5	10	15	534.593
#412	EHF	5	21	26	2995.881
#413	NR2F6	5	21	26	957.611
#414	MEIS2	5	15	20	1841.47
#415	NFE2L3	5	10	15	409.153
#416	MZF1	5	15	20	668.946
#417	RORA	5	19	24	1733.444
#418	ERG	5	11	16	950.892
#419	SATB2	5	17	22	624.751
#420	LHX6	5	11	16	596.416
#421	ATF6	5	11	16	927.781
#422	HOXB2	5	13	18	1899.951
#423	ZIC1	5	16	21	3002.503
#424	BARX1	5	7	12	250.502
#425	MSC	5	9	14	658.999
#426	NFX1	4	15	19	1829.761
#427	TFAP2C	4	17	21	851.152
#428	KLF4	4	24	28	1481.694
#429	ZNF268	4	17	21	304.211
#430	ARNT2	4	18	22	650.388
#431	BATF3	4	18	22	609.169
#432	TGIF2	4	18	22	1280.574
#433	TCF25	4	18	22	567.436
#434	TFEC	4	13	17	365.031
#435	ZNF3	4	10	14	627.936
#436	RCAN1	4	15	19	285.305
#437	ZSCAN18	4	17	21	878.259
#438	HEY1	4	19	23	1240.507
#439	HLF	4	15	19	313.364
#440	ADNP2	4	13	17	604.734
#441	PBX3	4	13	17	334.251
#442	GATA3	4	12	16	1054.707
#443	PEG3	4	9	13	423.429
#444	ZFHX4	3	10	13	325.177
#445	HOXA5	3	17	20	409.043
#446	HOXC10	3	21	24	1104.2
#447	RNF4	3	8	11	921.375
#448	POU2F3	3	9	12	207.617
#449	NR4A3	3	13	16	860.105
#450	ARNTL	3	10	13	448.907
#451	PLSCR1	3	15	18	126.5
#452	HOXD4	3	14	17	545.95
#453	TBX1	3	15	18	810.075
#454	TLX3	3	11	14	226.961
#455	HMG20B	3	15	18	1037.614
#456	PBX2	3	16	19	1259.353
#457	ZNF323	3	13	16	704.85
#458	SCML1	3	18	21	403.34
#459	IRX4	3	13	16	1314.018
#460	RFX5	3	18	21	162.098
#461	ZNF91	3	15	18	863.562
#462	ETS2	3	22	25	308.848
#463	HOXD3	3	9	12	922.879
#464	WT1	3	12	15	161.126
#465	HOXD1	3	18	21	491.969
#466	MLX	3	18	21	570.045
#467	NFIB	3	25	28	887.58
#468	DBP	3	8	11	664.898
#469	NR0B1	3	17	20	377.044
#470	MNT	3	18	21	420.473
#471	JUND	3	20	23	736.746
#472	SREBF1	3	13	16	740.947
#473	ZXDC	3	13	16	233.582
#474	TAF12	3	15	18	476.663
#475	CEBPD	3	17	20	1636.923
#476	SCMH1	3	11	14	212.502
#477	FOXA1	3	20	23	848.483
#478	EGR3	2	12	14	100.284
#479	ZFHX3	2	18	20	624.595
#480	FOXF2	2	15	17	509.836
#481	CEBPA	2	19	21	297.221
#482	CREB5	2	13	15	311.04
#483	HMGA2	2	20	22	567.777
#484	SRF	2	11	13	110.277
#485	HIRA	2	13	15	695.434
#486	MEOX1	2	15	17	212.98
#487	C11orf9	1	14	15	584.415
#488	FOXC1	1	13	14	118.107
#489	ESR1	1	24	25	218.02
#490	SUPT4H1	1	13	14	231.307
#491	ELF5	1	12	13	163.75
#492	HMBOX1	1	16	17	106.871
#493	CDKN2A	1	25	26	346.603
#494	NFYA	1	20	21	3073.31
#495	SMAD1	1	15	16	143.51
#496	PPARG	1	19	20	139.127
#497	ISL1	1	15	16	271.736
#498	ELF3	0	21	21	0
#499	RBCK1	0	16	16	0
#500	TCEAL1	0	16	16	0