Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	KLF2	67	4	71	329.575
#2	PAX8	57	13	70	759.816
#3	FLI1	51	6	57	2463.664
#4	EGR3	51	4	55	932.975
#5	ZEB2	46	8	54	1910.846
#6	SOX17	46	10	56	441.709
#7	IRF8	46	1	47	339.942
#8	STAT4	45	11	56	1766.845
#9	WT1	43	5	48	559.97
#10	TRIM22	42	5	47	78.754
#11	FOXN3	42	6	48	1084.861
#12	ZFPM2	42	10	52	506.518
#13	HCLS1	40	4	44	138.295
#14	MEF2C	40	9	49	739.216
#15	MECOM	38	7	45	898.128
#16	ETS2	38	12	50	1396.787
#17	RFXANK	38	10	48	425.424
#18	EGR2	36	6	42	283.755
#19	EPAS1	36	7	43	210.151
#20	NR2F6	35	10	45	690.53
#21	BHLHE41	34	8	42	805.598
#22	HOXA6	34	10	44	1022.689
#23	NR3C1	34	8	42	156.275
#24	ZNF135	33	11	44	1519.352
#25	CBFA2T3	33	16	49	2276.263
#26	ENO1	33	12	45	1013.338
#27	E2F8	33	11	44	1026.817
#28	STAT1	33	12	45	1589.758
#29	KLF5	33	6	39	599.78
#30	SCML1	32	11	43	976.723
#31	SP140	32	7	39	508.876
#32	MGA	32	8	40	776.245
#33	BCL11B	32	8	40	311.004
#34	CITED2	32	10	42	750.026
#35	NR4A3	31	13	44	674.381
#36	NR2F1	31	12	43	771.763
#37	AFF1	31	8	39	1005.258
#38	HOXD1	31	9	40	481.802
#39	EGR1	31	4	35	1806.814
#40	SNAI2	30	5	35	217.93
#41	TCF4	30	13	43	1430.03
#42	MEIS1	30	9	39	2037.315
#43	HMGA2	30	11	41	729.451
#44	FOXF1	29	8	37	952.772
#45	POU5F1B	29	11	40	1481.254
#46	ZBTB38	29	7	36	585.928
#47	HEY1	29	17	46	1203.449
#48	TFDP2	29	14	43	818.108
#49	MAF	29	11	40	1029.399
#50	ELF3	29	16	45	871.825
#51	MYCN	29	21	50	669.308
#52	FOXJ1	29	13	42	538.739
#53	SMAD1	29	11	40	2471.117
#54	CUX2	28	17	45	1315.627
#55	WNT5A	28	19	47	1363.024
#56	MZF1	28	15	43	1196.428
#57	KLF6	28	8	36	305.056
#58	SOX4	28	13	41	370.663
#59	KLF9	27	18	45	1292.014
#60	HOXB9	27	16	43	1552.948
#61	PPARG	27	14	41	458.2
#62	BATF	27	11	38	588.899
#63	IRF7	27	9	36	524.652
#64	GAS7	27	20	47	1120.996
#65	ASCL2	27	16	43	867.738
#66	YEATS4	26	19	45	941.764
#67	SALL1	26	12	38	470.031
#68	SOX13	26	16	42	1110.898
#69	BLZF1	26	6	32	363.993
#70	MAFB	26	9	35	1360.479
#71	HOXA5	26	18	44	936.243
#72	FOS	26	3	29	530.949
#73	TRIM29	26	16	42	1086.556
#74	GTF2I	26	10	36	751.83
#75	MYBL2	25	14	39	658.723
#76	PBX1	25	21	46	1006.491
#77	MYOG	25	11	36	774.584
#78	MAX	25	16	41	1730.453
#79	HOXB5	25	12	37	702.436
#80	FOXO1	25	15	40	826.876
#81	PEG3	25	8	33	840.573
#82	ALX1	25	17	42	1614.699
#83	PGR	25	21	46	1515.47
#84	IKZF1	25	18	43	885.724
#85	BTG2	25	11	36	1383.387
#86	MAFF	25	12	37	402.227
#87	HMX1	24	14	38	1508.992
#88	TAF4	24	15	39	770.535
#89	HOXA3	24	12	36	946.569
#90	ARID3A	24	18	42	2198.686
#91	CREB3L1	24	13	37	1136.208
#92	SOX9	24	17	41	1201.862
#93	PBX2	24	15	39	788.432
#94	MTF1	24	10	34	1027.372
#95	SIX3	24	24	48	1442.422
#96	NR4A2	24	15	39	3353.306
#97	GABPB1	24	15	39	1330.064
#98	HHEX	24	10	34	659.317
#99	ZNF167	24	12	36	1105.848
#100	REL	23	14	37	1068.866
#101	SPIB	23	15	38	453.364
#102	ETV4	23	15	38	892.366
#103	TFEC	23	15	38	429.275
#104	HNF1B	23	20	43	1436.173
#105	AR	23	17	40	1042.574
#106	CBFB	23	15	38	1149.034
#107	TAF12	23	22	45	1560.97
#108	JUNB	23	1	24	11.623
#109	SPI1	23	10	33	516.742
#110	ELF1	23	18	41	961.105
#111	SOX18	22	15	37	1372.586
#112	PTTG1	22	9	31	426.902
#113	LHX2	22	22	44	1317.715
#114	ELK3	22	20	42	1614.125
#115	TCF12	22	17	39	1298.499
#116	PLSCR1	22	11	33	651.099
#117	HOXA9	22	17	39	1101.418
#118	MMP14	22	22	44	1150.706
#119	ZNF45	21	22	43	1590.537
#120	HMGA1	21	13	34	484.767
#121	ZNF175	21	9	30	601.323
#122	PAX7	21	14	35	674.298
#123	NFATC3	21	10	31	574.303
#124	RORC	21	13	34	1153.46
#125	NR2E3	21	16	37	1133.751
#126	AEBP1	21	11	32	835.43
#127	ZBTB48	21	19	40	1314.062
#128	HOPX	21	14	35	677.505
#129	ZKSCAN5	21	10	31	1129.315
#130	ERG	21	20	41	1874.147
#131	MEOX2	21	18	39	612.226
#132	HOXC10	21	12	33	739.602
#133	GABPA	20	15	35	1121.821
#134	ASCL1	20	21	41	1935.852
#135	PRRX2	20	17	37	1118.831
#136	EGR4	20	15	35	734.635
#137	ATF6B	20	20	40	1588.254
#138	NPAT	20	18	38	1036.185
#139	ARNT2	20	14	34	640.262
#140	EHF	20	19	39	499.079
#141	CDX2	20	10	30	624.547
#142	HOXB6	20	11	31	1050.03
#143	BCL3	20	22	42	1509.941
#144	JUND	20	14	34	985.156
#145	ATF3	20	7	27	264.516
#146	ST18	20	15	35	988.22
#147	ONECUT1	20	21	41	1156.071
#148	HOXB7	20	18	38	1282.085
#149	FOSB	19	5	24	91.3
#150	MYF6	19	19	38	1489.792
#151	TLX3	19	17	36	2104.862
#152	ARNTL2	19	20	39	1875.726
#153	ATF6	19	19	38	960.993
#154	AHR	19	17	36	646.854
#155	ZNF238	19	14	33	675.578
#156	FOXO4	19	20	39	1344.597
#157	ECSIT	19	15	34	487.881
#158	ALS2CR8	19	10	29	488.802
#159	ZSCAN2	19	13	32	751.808
#160	SOX21	19	18	37	1182.434
#161	NR4A1	19	4	23	80.41
#162	ETV5	19	19	38	1322.015
#163	HOXD3	19	14	33	761.914
#164	NR1H4	19	16	35	1115.881
#165	HINFP	19	15	34	1020.753
#166	TCF7	19	19	38	1607.445
#167	LHX5	19	14	33	1024.164
#168	FOXI1	18	17	35	1310.75
#169	FOXL2	18	12	30	696.689
#170	TP73	18	13	31	846.285
#171	HLF	18	22	40	1344.43
#172	FOXC1	18	17	35	1028.761
#173	E2F5	18	16	34	202.205
#174	ESRRA	18	19	37	1137.65
#175	ETS1	18	13	31	932.71
#176	FOXM1	18	14	32	470.891
#177	HOXA10	18	19	37	1077.823
#178	HEY2	18	22	40	932.03
#179	HOXD11	18	13	31	878.433
#180	HOXA4	18	19	37	1305.116
#181	NR2E1	18	13	31	1134.107
#182	POU6F1	18	17	35	1530.384
#183	NFYB	18	9	27	609.574
#184	MSRB2	18	13	31	1130.907
#185	NKX3-2	18	17	35	795.888
#186	NEUROG1	18	16	34	1047.896
#187	SATB1	18	20	38	703.519
#188	JUN	18	9	27	1029.604
#189	SMAD5	18	14	32	598.862
#190	GATA1	18	20	38	939.586
#191	HOXA1	18	11	29	449.651
#192	FOSL2	18	17	35	715.774
#193	NR3C2	17	19	36	776.399
#194	PROX1	17	18	35	1730.143
#195	ZNF446	17	14	31	880.143
#196	GATA6	17	10	27	894.792
#197	PLAG1	17	16	33	1166.983
#198	RXRB	17	19	36	909.91
#199	SIM2	17	21	38	1049.098
#200	SP1	17	19	36	802.628
#201	CLOCK	17	21	38	1462.292
#202	ZNF117	17	13	30	725.187
#203	ALX4	17	19	36	1259.347
#204	MEOX1	17	18	35	884.093
#205	SOX2	17	25	42	1031.202
#206	FOXP3	17	16	33	987.082
#207	ESRRB	17	19	36	1473.454
#208	MLL	17	23	40	1235.869
#209	C2orf3	17	17	34	1147.668
#210	ZEB1	17	23	40	1098.961
#211	TFAP2A	17	21	38	1701.152
#212	MNX1	17	20	37	1024.74
#213	LHX6	17	18	35	1299.719
#214	ZFP36L2	17	13	30	585.586
#215	RUNX1T1	17	24	41	821.319
#216	KLF4	17	17	34	481.678
#217	PAX6	17	20	37	1310.145
#218	ZHX3	17	19	36	1891.085
#219	SMAD6	17	22	39	1055.742
#220	ZFP36L1	17	20	37	1010.984
#221	MLXIPL	16	23	39	1115.982
#222	RUNX2	16	12	28	498.458
#223	POU3F3	16	19	35	1112.316
#224	TFAP4	16	18	34	1153.668
#225	ESRRG	16	16	32	526.178
#226	HOXB1	16	14	30	789.88
#227	HESX1	16	19	35	880.518
#228	RERE	16	20	36	1371.731
#229	FOXG1	16	21	37	1200.584
#230	IRX4	16	23	39	1158.357
#231	ZGPAT	16	18	34	825.009
#232	TFAP2C	16	15	31	601.772
#233	E2F1	16	16	32	441.214
#234	TSC22D3	16	16	32	503.029
#235	RFX3	16	16	32	862.782
#236	SUPT6H	16	15	31	801.193
#237	E2F4	16	15	31	951.181
#238	PPARA	16	12	28	635.726
#239	C11orf9	16	15	31	513.376
#240	RXRA	16	21	37	1578.051
#241	LHX1	16	16	32	666.915
#242	GATA4	16	16	32	573.92
#243	HIC1	16	12	28	512.791
#244	ETV1	16	18	34	971.697
#245	MYC	15	16	31	731.638
#246	LZTS1	15	19	34	878.074
#247	TAF1B	15	14	29	805.839
#248	CEBPA	15	23	38	704.844
#249	TP63	15	19	34	695.342
#250	POU3F2	15	15	30	886.044
#251	HOXB2	15	14	29	820.433
#252	ZNF643	15	22	37	903.443
#253	MEF2A	15	17	32	1578.973
#254	ARNT	15	23	38	1327.384
#255	RUNX1	15	18	33	783.73
#256	MYF5	15	24	39	1445.874
#257	PPBPL2	15	17	32	820.733
#258	NR1I2	15	17	32	1052.906
#259	ETV2	15	20	35	1070.689
#260	TCF15	15	15	30	590.467
#261	FOXN2	15	18	33	1043.987
#262	TBR1	15	16	31	604.922
#263	MAFK	15	20	35	828.543
#264	PITX2	15	24	39	1180.156
#265	BHLHE40	15	21	36	699.283
#266	RUNX3	15	21	36	1059.677
#267	GATA3	15	17	32	437.153
#268	MSX2	15	17	32	694.414
#269	MSX1	15	19	34	507.575
#270	TAF13	15	22	37	1616.424
#271	NEUROD1	15	17	32	934.663
#272	CITED1	15	16	31	747.16
#273	SOX11	15	23	38	1237.849
#274	HOXA7	15	18	33	840.884
#275	BNC1	14	16	30	603.31
#276	FOXD1	14	20	34	1104.581
#277	ZNF157	14	22	36	762.457
#278	NR5A2	14	26	40	625.264
#279	NPAS2	14	16	30	620.339
#280	NFYA	14	17	31	1013.565
#281	ZNF639	14	21	35	1175.4
#282	TFAP2B	14	21	35	1094.741
#283	NR2F2	14	23	37	1437.361
#284	PDX1	14	15	29	974.356
#285	GBX2	14	24	38	964.698
#286	TWIST1	14	12	26	437.451
#287	PPARD	14	19	33	1242.348
#288	DLX6	14	15	29	618.739
#289	VDR	14	15	29	1071.358
#290	FOXA1	14	18	32	835.755
#291	TRIM25	14	19	33	1591.458
#292	MBD1	14	17	31	889.971
#293	MYCL1	14	18	32	570.125
#294	HOXB8	14	20	34	1296.769
#295	FUBP1	14	26	40	1166.424
#296	NKX6-1	14	21	35	813.476
#297	ZHX2	14	17	31	788.867
#298	HOXC13	14	14	28	1028.662
#299	STAT2	14	19	33	705.662
#300	PHTF1	14	13	27	545.401
#301	MSC	14	14	28	600.389
#302	NANOG	14	14	28	1286.557
#303	NFIC	13	19	32	2201.302
#304	NR1I3	13	17	30	734.679
#305	SIM1	13	19	32	889.04
#306	HES1	13	14	27	824.612
#307	ZXDC	13	16	29	802.286
#308	PRDM1	13	19	32	593.413
#309	HOXA2	13	18	31	1018.375
#310	RARA	13	22	35	929.393
#311	TCF21	13	13	26	368.61
#312	HMBOX1	13	19	32	836.039
#313	IKZF3	13	21	34	870.207
#314	FOXC2	13	18	31	856.764
#315	SIX1	13	23	36	1014.48
#316	POU2F3	13	16	29	455.602
#317	ESR2	13	19	32	661.36
#318	NKX2-5	13	17	30	939.304
#319	KLF15	13	20	33	631.991
#320	POU2F2	13	16	29	398.77
#321	ZKSCAN4	13	10	23	382.135
#322	CBFA2T2	13	19	32	635.638
#323	POU3F4	13	14	27	369.943
#324	HNF1A	13	17	30	746.721
#325	NR0B1	13	23	36	956.796
#326	TEAD4	13	16	29	359.384
#327	RORB	13	16	29	679.035
#328	ATF5	13	21	34	1435.803
#329	CSRNP3	13	24	37	969.648
#330	TFDP1	13	14	27	481.339
#331	OLIG2	13	20	33	711.693
#332	DMRT1	13	19	32	656.372
#333	CEBPE	12	19	31	766.745
#334	NFX1	12	20	32	658.632
#335	TADA2A	12	17	29	639.56
#336	FOXA2	12	27	39	1165.884
#337	E2F2	12	20	32	1202.248
#338	HOXD10	12	7	19	204.295
#339	SPDEF	12	22	34	925.927
#340	HAND1	12	14	26	836.601
#341	PAX4	12	18	30	761.423
#342	ZNF165	12	21	33	454.963
#343	CDKN2A	12	24	36	821.083
#344	NFE2	12	29	41	898.4
#345	CREBZF	12	18	30	732.734
#346	EN2	12	19	31	1814.408
#347	IRF4	12	21	33	983.83
#348	FOSL1	12	20	32	519.545
#349	PKNOX2	12	21	33	670.233
#350	ZNF75D	12	13	25	535.701
#351	NKX2-1	12	14	26	547.697
#352	T	12	15	27	628.75
#353	REST	12	17	29	548.82
#354	ZNF155	12	20	32	776.16
#355	ZNF236	12	20	32	788.698
#356	ZNF444	12	20	32	524.507
#357	KDM5B	12	30	42	1127.523
#358	LEF1	12	18	30	733.015
#359	TADA3	12	15	27	574.5
#360	TP53	12	27	39	888.626
#361	FOXB1	12	15	27	1218.635
#362	HOXD13	12	8	20	490.122
#363	NR2C1	12	19	31	830.154
#364	HSF1	11	21	32	784.908
#365	POU3F1	11	25	36	951.477
#366	FOXO3	11	17	28	533.916
#367	BARX1	11	19	30	866.127
#368	ZSCAN12	11	19	30	893.225
#369	HOXB3	11	16	27	746.918
#370	MYT1L	11	15	26	630.547
#371	ALX3	11	19	30	758.488
#372	TBX19	11	23	34	1302.282
#373	SOX5	11	23	34	610.331
#374	RFXAP	11	26	37	979.333
#375	USF2	11	22	33	982.6
#376	RARG	11	20	31	757.528
#377	HIF3A	11	26	37	809.943
#378	ZNF132	11	21	32	718.64
#379	GATA2	11	17	28	531.402
#380	NFKB2	11	17	28	562.683
#381	LMO4	11	14	25	556.768
#382	CRX	11	17	28	749.365
#383	ELF4	11	24	35	751.732
#384	FOXE1	11	20	31	714.887
#385	HOXD4	11	7	18	237.976
#386	STRN3	11	27	38	1411.625
#387	TBX2	11	20	31	677.589
#388	ELF5	11	30	41	1410.011
#389	PHOX2B	11	18	29	597.356
#390	HMG20B	10	21	31	504.945
#391	SP4	10	18	28	618.166
#392	NR6A1	10	18	28	811.29
#393	TRPS1	10	18	28	977.64
#394	IRX5	10	25	35	1031.462
#395	SMAD3	10	14	24	500.224
#396	CEBPD	10	16	26	799.847
#397	TBX6	10	22	32	591.731
#398	NKX2-8	10	21	31	677.536
#399	ELK1	10	21	31	869.947
#400	MYT1	10	16	26	466.715
#401	MXD1	10	17	27	656
#402	GLI2	10	20	30	848.886
#403	MEF2D	10	19	29	842.069
#404	YY1	10	18	28	783.256
#405	ZSCAN18	10	14	24	438.469
#406	SRY	10	17	27	774.688
#407	MLLT10	10	16	26	500.055
#408	NFATC1	10	23	33	973.703
#409	PITX1	10	30	40	1331.511
#410	ZIC3	10	21	31	1027.608
#411	ZNF80	10	31	41	929.993
#412	TFDP3	10	21	31	910.256
#413	DLX2	10	19	29	425.772
#414	ISL1	10	14	24	572.176
#415	TFEB	10	19	29	962.606
#416	PRDM2	10	24	34	737.608
#417	TSC22D2	9	19	28	560.22
#418	NPAS1	9	23	32	717.808
#419	ZNF202	9	23	32	621.346
#420	HOXD9	9	18	27	590.741
#421	FOXD3	9	18	27	429.03
#422	NFIX	9	19	28	605.217
#423	HOXA11	9	24	33	661.337
#424	PHF1	9	24	33	839.164
#425	CSDA	9	21	30	506.219
#426	FOXD2	9	22	31	602.028
#427	EMX1	9	14	23	319.536
#428	HNF4G	9	14	23	573.327
#429	ONECUT2	9	23	32	696.252
#430	TCF3	9	21	30	658.229
#431	VTN	9	23	32	1130.826
#432	CTBP1	9	17	26	723.377
#433	TSHZ2	9	13	22	403.024
#434	ESR1	9	17	26	505.816
#435	VENTX	9	14	23	450.972
#436	ZNF81	9	21	30	1082.65
#437	ZBTB25	9	15	24	540.642
#438	TBX3	9	30	39	628.476
#439	MEIS2	9	20	29	615.741
#440	MYOD1	9	17	26	541.967
#441	ZNF3	9	23	32	944.567
#442	ETV3	8	17	25	484.361
#443	IRF5	8	22	30	666.155
#444	GCM1	8	24	32	887.679
#445	SNAPC5	8	24	32	498.901
#446	NRL	8	17	25	408.109
#447	TLX2	8	20	28	437.679
#448	DBP	8	20	28	487.731
#449	ZKSCAN1	8	21	29	638.522
#450	ARNTL	8	20	28	835.878
#451	SATB2	8	25	33	789.98
#452	PAX5	8	21	29	837.591
#453	CREM	8	17	25	408.47
#454	PAX3	8	22	30	542.525
#455	TAL1	8	17	25	451.701
#456	NR5A1	8	23	31	575.776
#457	SCRT1	8	20	28	901.087
#458	ZFP37	8	18	26	341.644
#459	SOX30	7	26	33	795.164
#460	HNF4A	7	22	29	515.845
#461	HOXC5	7	19	26	402.737
#462	OVOL1	7	21	28	428.778
#463	PHOX2A	7	26	33	593.585
#464	CREB5	7	18	25	437.071
#465	SOX15	7	22	29	663.375
#466	NFAT5	7	21	28	603.565
#467	PKNOX1	7	28	35	642.159
#468	KLF12	7	17	24	528.451
#469	TBX1	7	28	35	654.617
#470	ZNF41	7	23	30	508.524
#471	POU4F3	7	22	29	732.376
#472	SCAND2	6	18	24	375.34
#473	NFIB	6	24	30	744.92
#474	GSC2	6	23	29	490.292
#475	EN1	6	23	29	387.147
#476	THRA	6	24	30	450.125
#477	HOXC8	6	16	22	307.181
#478	POU1F1	6	32	38	644.501
#479	BATF3	6	21	27	599.446
#480	CREBBP	6	16	22	336.85
#481	TEF	6	24	30	651.922
#482	RARB	6	18	24	274.983
#483	FOXH1	6	21	27	564.587
#484	RB1	6	22	28	297.228
#485	ZNF174	6	24	30	400.746
#486	PTH	5	21	26	317.299
#487	ZNF287	5	20	25	285.629
#488	ELK4	5	22	27	450.878
#489	HEYL	5	18	23	272.9
#490	POU4F1	5	27	32	365.766
#491	RCAN1	5	23	28	321.355
#492	ATOH1	5	18	23	339.943
#493	BRD8	4	23	27	390.084
#494	SNAPC4	4	19	23	549.384
#495	NFATC4	4	21	25	406.865
#496	ZIC1	4	37	41	441.086
#497	TCF7L2	4	19	23	212.23
#498	ZNF154	4	27	31	379.794
#499	TBX5	3	20	23	180.648
#500	SLC26A3	2	28	30	146.563