Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF175	32	5	37	2237.59
#2	CRX	28	0	28	0
#3	POU4F2	27	10	37	5504.115
#4	RNF4	26	3	29	832.864
#5	KLF7	25	10	35	6349.317
#6	C5orf41	24	2	26	5280.387
#7	TCF7	24	1	25	1039.418
#8	ELF4	24	2	26	10233.143
#9	BCL3	23	8	31	1277.742
#10	ZNF131	22	3	25	542.856
#11	LHX3	22	8	30	6235.685
#12	CDKN2A	22	1	23	322.487
#13	DDIT3	22	3	25	433.267
#14	SMAD5	22	4	26	709.319
#15	DMRT1	22	8	30	827.216
#16	MXD1	21	1	22	409.273
#17	FOXA3	21	8	29	827.061
#18	ZNF444	20	5	25	5114.096
#19	MYT1	20	4	24	157.506
#20	MLL	20	6	26	3865.011
#21	ZFP36L1	20	4	24	1040.103
#22	SMAD4	20	11	31	3843.015
#23	ZNF189	20	10	30	2227.977
#24	ZNF165	19	3	22	775.438
#25	TBX5	19	5	24	1034.254
#26	SUPT6H	19	5	24	618.102
#27	ARX	19	2	21	169.524
#28	HOXB7	19	6	25	2760.271
#29	TFAM	19	7	26	980.08
#30	FOXM1	19	8	27	4273.319
#31	DLX3	19	6	25	585.834
#32	IRF4	18	6	24	1046.214
#33	WNT5A	18	7	25	1712.232
#34	ZNF238	18	3	21	525.255
#35	TLX2	18	7	25	571.119
#36	ZNF24	18	5	23	2095.93
#37	TFAP2E	18	6	24	1528.477
#38	RB1	18	2	20	224.112
#39	SALL2	18	8	26	2586.765
#40	LMO4	18	4	22	443.994
#41	ZKSCAN4	17	9	26	3411.853
#42	IRF5	17	3	20	251.056
#43	ESX1	17	6	23	1887.843
#44	YY1	17	8	25	3226.762
#45	HESX1	17	6	23	1278.954
#46	PLAGL2	17	11	28	2297.25
#47	OLIG2	17	8	25	2346.436
#48	HOXC4	17	5	22	681.248
#49	TBP	17	4	21	1118.587
#50	STAT3	17	5	22	804.266
#51	ELK4	16	9	25	1643.395
#52	ARNT2	16	6	22	890.17
#53	LHX5	16	5	21	826.979
#54	JUND	16	5	21	861.837
#55	TP63	16	6	22	669.636
#56	NOTCH1	16	12	28	1941.837
#57	CREB1	16	7	23	816.224
#58	ZEB1	16	3	19	231.728
#59	LZTR1	16	5	21	557.246
#60	RARA	16	7	23	1676.641
#61	JUNB	16	5	21	1058.262
#62	POU6F2	16	11	27	1483.515
#63	AHCTF1	16	7	23	1917.222
#64	TBX4	16	3	19	381.384
#65	TP53	16	8	24	667.255
#66	NKX1-2	16	7	23	3454.946
#67	ZNF277	16	7	23	941.257
#68	SIX1	15	4	19	482.084
#69	RBPJ	15	4	19	561.842
#70	IRX1	15	5	20	1804.841
#71	DRAP1	15	8	23	2473.297
#72	HNRNPAB	15	2	17	733.165
#73	HOXC6	15	7	22	1216.009
#74	FOXI3	15	7	22	1707.083
#75	ARNT	15	4	19	11626.517
#76	NKX2-1	15	6	21	404.464
#77	PRDM1	15	9	24	2654.367
#78	BATF2	15	5	20	292.847
#79	MEIS3	15	8	23	3022.17
#80	ST18	15	9	24	1339.323
#81	GRHL3	15	10	25	6249.328
#82	TBX3	14	12	26	3247.766
#83	EGR2	14	6	20	2160.097
#84	TFDP2	14	8	22	1736.524
#85	SNAPC4	14	8	22	1620.058
#86	ZNF639	14	6	20	491.831
#87	CSRNP3	14	11	25	1139.884
#88	OTX1	14	5	19	1019.915
#89	ETV4	14	8	22	1643.512
#90	VENTX	14	5	19	1538.56
#91	ZNF256	14	10	24	4798.797
#92	CREBL2	14	4	18	463.189
#93	PAX6	14	8	22	1867.546
#94	MYF6	14	9	23	3335.512
#95	LMX1B	14	6	20	1075.8
#96	ZNF133	14	2	16	142.946
#97	RBPJL	14	9	23	1537.593
#98	NOLC1	14	6	20	428.77
#99	AR	14	9	23	2666.883
#100	HIC1	14	13	27	2459.811
#101	ZXDC	14	8	22	4864.781
#102	REL	14	5	19	1715.353
#103	RUNX1T1	13	9	22	1768.573
#104	ZNF202	13	8	21	2621.729
#105	PBX3	13	4	17	1190.679
#106	MYT1L	13	13	26	2657.16
#107	C1orf85	13	8	21	1512.261
#108	EN1	13	16	29	3202.943
#109	NME2	13	5	18	669.127
#110	FOXC1	13	5	18	228.332
#111	NFE2L2	13	9	22	4225.542
#112	TEF	13	3	16	647.619
#113	RAX2	13	4	17	105.836
#114	TBX19	13	7	20	7735.358
#115	SOX17	13	7	20	1833.181
#116	FOXD2	13	13	26	2066.233
#117	HIF1A	13	4	17	1397.025
#118	BATF3	13	3	16	153.393
#119	RARG	13	12	25	1879.504
#120	ZNF232	12	6	18	1502.448
#121	NR2E3	12	6	18	1475.161
#122	MLLT10	12	7	19	427.304
#123	ESRRA	12	5	17	292.946
#124	FOXO3	12	8	20	2154.452
#125	GLI2	12	6	18	961.614
#126	EOMES	12	11	23	2648.508
#127	ZFPM2	12	4	16	444.829
#128	HOXB5	12	9	21	1443.074
#129	TSC22D4	12	9	21	2281.321
#130	SIN3A	12	12	24	1594.193
#131	TFAP2A	12	7	19	578.328
#132	SOX7	12	10	22	3584.577
#133	ATF2	12	11	23	1405.687
#134	USF2	12	13	25	2870.709
#135	CREB3	12	12	24	5407.023
#136	PKNOX1	12	6	18	1074.004
#137	NFKB2	12	6	18	1561.515
#138	ZNF449	12	4	16	1046.994
#139	MYOG	12	11	23	2176.046
#140	FOXJ1	12	4	16	1002.84
#141	FBXW7	11	11	22	2361.834
#142	ELF3	11	4	15	385.673
#143	ZSCAN29	11	12	23	3275.283
#144	PPARA	11	8	19	2482.914
#145	SCAND2	11	11	22	2927.239
#146	POU5F2	11	5	16	1142.15
#147	EN2	11	6	17	779.21
#148	PCGF6	11	9	20	2081.157
#149	ZFP90	11	9	20	664.497
#150	NEUROD1	11	9	20	2440.141
#151	IRX4	11	6	17	2582.359
#152	BARX1	11	4	15	194.736
#153	NR1H2	11	7	18	636.765
#154	FOXP2	11	7	18	681.99
#155	E4F1	11	9	20	2462.561
#156	TULP4	11	6	17	482.605
#157	SMAD1	11	11	22	2008.596
#158	TFEC	11	9	20	2049.614
#159	TCF3	11	6	17	422.097
#160	ZNF174	11	4	15	414.261
#161	ERF	11	4	15	728.381
#162	MTA3	11	9	20	3162.434
#163	GLIS3	11	7	18	3116.887
#164	RERE	11	9	20	1039.13
#165	MAF	11	7	18	2242.617
#166	ZSCAN10	11	8	19	1645.349
#167	IRX3	11	6	17	852.608
#168	NFATC2	11	13	24	2087.316
#169	E2F4	11	11	22	1713.306
#170	CREBZF	11	6	17	1640.489
#171	GSC2	11	7	18	597.558
#172	MLXIPL	11	14	25	2476.508
#173	ZNF85	11	13	24	3825.214
#174	ELF5	10	9	19	1904.582
#175	RORB	10	9	19	876.547
#176	HOXA9	10	8	18	506.86
#177	FOXD3	10	4	14	333.677
#178	NR1D1	10	7	17	968.123
#179	ZFPM1	10	7	17	2391.474
#180	RORA	10	9	19	2626.338
#181	SOX4	10	12	22	2541.998
#182	PURB	10	4	14	220.25
#183	TFDP1	10	9	19	1184.77
#184	LHX2	10	11	21	2796.112
#185	GATAD2A	10	15	25	3426.512
#186	OVOL1	10	5	15	619.259
#187	FOXP3	10	16	26	2823.179
#188	NR2C1	10	3	13	1014.929
#189	DMTF1	10	11	21	1634.126
#190	ARNTL2	10	2	12	1252.818
#191	FOSB	10	8	18	1340.41
#192	TCF7L2	10	9	19	1366.767
#193	PHF1	10	7	17	477.622
#194	MAFK	10	11	21	3419.147
#195	FOXR1	10	9	19	1290.625
#196	TRIM29	10	8	18	1457.42
#197	CEBPB	10	9	19	2067.347
#198	HMGB1	10	7	17	483.96
#199	ZC3H8	10	9	19	1112.418
#200	SOX12	10	5	15	983.147
#201	HMGA2	10	12	22	815.765
#202	ADNP2	10	14	24	1909.321
#203	CTNNB1	10	11	21	526.179
#204	ETV7	10	9	19	2585.823
#205	ZBTB48	10	5	15	582.255
#206	CBFB	9	12	21	2126.246
#207	TFDP3	9	7	16	2198.352
#208	TAL1	9	9	18	765.165
#209	HCFC1	9	13	22	2317.23
#210	AEBP1	9	7	16	1499.238
#211	NFYC	9	6	15	699.77
#212	ESR1	9	8	17	2789.365
#213	NFE2L1	9	8	17	1565.747
#214	ZNF33A	9	9	18	1689.068
#215	PPARD	9	3	12	1027.088
#216	SOX2	9	8	17	1145.788
#217	FOXK1	9	13	22	2924.919
#218	HOXA11	9	11	20	1978.786
#219	HOXA4	9	5	14	282.325
#220	ZNF134	9	10	19	2596.245
#221	TSC22D2	9	5	14	617.37
#222	TMEM229A	9	12	21	2710.322
#223	ZFP42	9	14	23	837.881
#224	ETV3	9	10	19	1096.469
#225	IRF3	9	7	16	987.25
#226	VDR	9	16	25	3752.908
#227	E2F8	9	11	20	2288.268
#228	SOX8	9	10	19	1575.491
#229	TSHZ2	9	8	17	1455.621
#230	RCOR2	9	13	22	4150.252
#231	NFIB	9	9	18	668.331
#232	CREB3L3	9	11	20	1447.499
#233	ZNF215	8	8	16	1542.632
#234	ATF6B	8	11	19	1381.986
#235	NFE2L3	8	9	17	607.713
#236	JUN	8	11	19	728.069
#237	FOXE1	8	14	22	3325.368
#238	THRB	8	10	18	1746.417
#239	ATF6	8	8	16	557.576
#240	LHX9	8	9	17	1196.123
#241	LHX1	8	7	15	1918.854
#242	RHOXF2B	8	5	13	209.11
#243	HDAC1	8	15	23	3130.097
#244	FOXG1	8	11	19	2320.762
#245	MLX	8	13	21	2076.749
#246	IKZF1	8	12	20	1126.864
#247	SOLH	8	10	18	2515.362
#248	SP1	8	17	25	1716.436
#249	ZNF219	8	5	13	1355.144
#250	TSC22D3	8	9	17	1673.53
#251	TRIM25	8	9	17	550.006
#252	E2F6	8	7	15	1083.238
#253	CREB3L1	8	8	16	1178.881
#254	GRHL2	8	7	15	1134.868
#255	RAX	8	9	17	491.416
#256	POU3F2	8	7	15	451.88
#257	POU3F3	8	8	16	2633.781
#258	PRRX1	8	10	18	1798.807
#259	ZNF75D	8	6	14	1307.199
#260	TGIF2LY	8	13	21	3339.714
#261	GTF2IRD1	8	9	17	1542.882
#262	ZNF37A	8	5	13	539.616
#263	BACH1	8	5	13	1543.554
#264	RHOXF2	8	7	15	1150.388
#265	E2F2	8	10	18	1425.446
#266	HNF4A	8	9	17	1197.961
#267	SCML1	8	6	14	1940.061
#268	NFE2	8	11	19	1608.825
#269	NFIX	8	9	17	912.379
#270	ZNF193	7	4	11	594.592
#271	BTAF1	7	13	20	1432.494
#272	TCF21	7	9	16	1411.126
#273	FOXA1	7	11	18	1118.753
#274	GATA2	7	8	15	668.719
#275	CUX1	7	6	13	415.946
#276	ZNF445	7	12	19	2403.666
#277	CNOT7	7	11	18	2499.085
#278	BRD8	7	10	17	753.979
#279	SNAPC5	7	9	16	2271.121
#280	MNT	7	9	16	833.516
#281	USF1	7	9	16	927.572
#282	NEUROD2	7	14	21	2795.066
#283	NKX6-1	7	11	18	1448.246
#284	NFATC4	7	8	15	981.329
#285	ZKSCAN1	7	9	16	833.278
#286	ATF3	7	9	16	1939.081
#287	SMAD3	7	11	18	1144.668
#288	STAT5B	7	12	19	972.492
#289	HOXD9	7	9	16	519.936
#290	EVX1	7	8	15	650.024
#291	ELK1	7	7	14	412.036
#292	TWIST1	7	11	18	1019.931
#293	ZIC5	7	12	19	3320.908
#294	TRIM28	7	10	17	1611.134
#295	NFYA	7	9	16	605.471
#296	GTF2I	7	9	16	1872.394
#297	TAF4	7	6	13	1373.376
#298	ATF7	7	7	14	1447.174
#299	ZNF207	7	11	18	1839.145
#300	EGR1	7	9	16	699.731
#301	POU3F4	7	5	12	212.714
#302	KDM5B	7	8	15	715.205
#303	ZNF397	7	9	16	742.037
#304	TSHZ3	7	10	17	470.998
#305	BARHL1	7	11	18	1790.958
#306	PGR	7	8	15	398.497
#307	ZEB2	7	10	17	695.401
#308	HMGA1	6	8	14	943.279
#309	ZNF81	6	2	8	22.446
#310	MEIS1	6	13	19	2092.182
#311	FOXJ3	6	11	17	1172.493
#312	BLZF1	6	12	18	832.811
#313	ZIC1	6	8	14	792.922
#314	ZSCAN2	6	6	12	110.671
#315	ZSCAN16	6	10	16	1109.492
#316	CNOT8	6	11	17	2106.716
#317	HOXB3	6	11	17	1350.321
#318	ZNF148	6	6	12	1341.529
#319	SCAND3	6	9	15	1208.103
#320	KLF16	6	10	16	1920.422
#321	ETV6	6	12	18	1223.145
#322	CCRN4L	6	10	16	1739.23
#323	FOSL2	6	9	15	4441.61
#324	FUBP1	6	7	13	11462.574
#325	MSX2	6	8	14	640.331
#326	MEOX1	6	13	19	1044.944
#327	PAX3	6	10	16	899.899
#328	LHX4	6	5	11	573.728
#329	ASCL2	6	9	15	1063.334
#330	ELF1	6	12	18	474.111
#331	ZFHX4	6	14	20	4996.782
#332	FOS	6	11	17	668.222
#333	RELA	6	12	18	931.03
#334	KLF6	6	9	15	771.396
#335	MYPOP	6	18	24	1479.267
#336	TP73	6	13	19	1285.804
#337	VSX1	6	8	14	469.122
#338	ETV3L	6	8	14	516.791
#339	FOXN4	5	12	17	1683.134
#340	HOXD13	5	11	16	643.041
#341	RXRA	5	9	14	960.749
#342	MYCN	5	11	16	1168.378
#343	NKX2-3	5	9	14	738.492
#344	SMAD9	5	17	22	1357.858
#345	NFIA	5	12	17	1169.504
#346	STAT1	5	12	17	985.28
#347	NFAT5	5	10	15	1003.46
#348	MNX1	5	17	22	1119.83
#349	SIX3	5	8	13	1120.235
#350	ZNF135	5	12	17	1701.025
#351	SOX9	5	8	13	849.303
#352	NR3C1	5	7	12	1384.955
#353	KLF12	5	8	13	395.264
#354	GCFC1	5	10	15	900.506
#355	FOXD1	5	8	13	540.278
#356	TSC22D1	5	8	13	1354.82
#357	ZNF213	5	9	14	1135.664
#358	LEF1	5	9	14	1284.29
#359	ZNF167	5	8	13	2616.314
#360	EMX1	5	12	17	1714.762
#361	ZFHX2	5	11	16	1699.242
#362	RORC	5	11	16	1521.201
#363	FOXP1	5	9	14	4239.649
#364	RFXANK	5	13	18	2183.706
#365	MYF5	5	13	18	513.114
#366	MAX	5	13	18	400.923
#367	HES5	5	6	11	777.328
#368	TBX6	5	15	20	3449.659
#369	TCFL5	5	12	17	631.55
#370	SPDEF	5	6	11	1044.201
#371	ZSCAN4	5	8	13	551.438
#372	ZSCAN1	5	9	14	2057.344
#373	AFF1	5	7	12	2019.047
#374	SIM2	5	13	18	1604.638
#375	CITED2	5	7	12	617.577
#376	KLF3	4	10	14	495.708
#377	XBP1	4	5	9	1282.711
#378	PKNOX2	4	10	14	466.26
#379	PHF5A	4	12	16	612.545
#380	RUNX1	4	10	14	1690.781
#381	PHTF1	4	18	22	2759.418
#382	MAFA	4	8	12	186.573
#383	PTH	4	13	17	1772.79
#384	KLF15	4	11	15	811.576
#385	STAT2	4	11	15	1631.562
#386	NRL	4	14	18	2560.732
#387	FOXD4	4	12	16	789.292
#388	POU2F2	4	10	14	1434.526
#389	LHX6	4	9	13	499.885
#390	RCOR1	4	10	14	1856.574
#391	BTG2	4	8	12	279.172
#392	MITF	4	11	15	968.82
#393	ZNF140	4	11	15	719.725
#394	UBN1	4	14	18	427.29
#395	PPARG	4	9	13	1778.803
#396	FOSL1	4	11	15	487.307
#397	CEBPA	4	18	22	1385.711
#398	FOXL1	4	8	12	449.868
#399	EHF	4	11	15	1435.729
#400	HOXC8	4	10	14	1176.307
#401	ZNF187	4	16	20	2915.48
#402	NFX1	4	12	16	2079.755
#403	HSF2	4	8	12	299.88
#404	ESRRB	4	14	18	539.886
#405	TPRX1	4	15	19	2206.5
#406	NPAS2	4	14	18	1246
#407	HMG20A	4	8	12	614.984
#408	SMAD2	4	11	15	953.753
#409	SOX30	4	9	13	702.815
#410	HOXA10	4	7	11	407.708
#411	MECOM	4	11	15	935.845
#412	ZSCAN18	4	11	15	760.848
#413	FOXJ2	4	13	17	568.341
#414	CLOCK	3	10	13	598.777
#415	NFKB1	3	9	12	239.421
#416	FOXO4	3	9	12	360.761
#417	ATOH1	3	7	10	236.122
#418	CSDA	3	8	11	438.701
#419	SREBF1	3	5	8	1148.074
#420	PROX1	3	11	14	1100.412
#421	ETS2	3	13	16	1625.127
#422	GTF2H3	3	13	16	984.573
#423	E2F1	3	8	11	756.116
#424	L3MBTL4	3	18	21	1175.782
#425	DLX2	3	10	13	1146.107
#426	SIX6	3	9	12	1523.509
#427	STAT6	3	13	16	481.135
#428	SOX5	3	10	13	1221.054
#429	TFCP2	3	14	17	3051.731
#430	ZHX2	3	8	11	183.441
#431	CREB3L4	3	7	10	807.675
#432	HOXB6	3	16	19	539.027
#433	MGA	3	10	13	422.289
#434	IRX2	3	13	16	1018.885
#435	ZNF500	3	10	13	399.83
#436	HIF3A	3	9	12	908.238
#437	NCOR1	3	10	13	326.47
#438	RELB	3	5	8	243.979
#439	ARNTL	3	10	13	427.787
#440	ALX1	3	13	16	1832.996
#441	ZNF19	3	10	13	182.666
#442	ZBTB25	3	8	11	213.05
#443	IRX5	3	14	17	235.677
#444	ELK3	2	14	16	833.372
#445	CREM	2	8	10	217.965
#446	NR2F1	2	7	9	321.282
#447	PBX1	2	8	10	294.243
#448	TFE3	2	10	12	243.737
#449	CTBP1	2	11	13	328.29
#450	ONECUT2	2	8	10	338.038
#451	THRA	2	7	9	90.986
#452	TCF4	2	14	16	560.434
#453	TCF20	2	7	9	203.092
#454	SP140	2	10	12	514.785
#455	SRF	2	10	12	346.128
#456	HNF1A	2	8	10	232.36
#457	AFF4	2	13	15	156.004
#458	FOXK2	2	9	11	337.384
#459	POU5F1	2	9	11	375.161
#460	NFIL3	2	9	11	1125.584
#461	ZKSCAN2	2	11	13	1112.103
#462	SOX11	2	7	9	872.163
#463	PAX8	2	8	10	872.856
#464	ESR2	2	15	17	1105.696
#465	SOX10	2	11	13	1164.457
#466	SP4	2	12	14	548.662
#467	SOX6	2	8	10	237.104
#468	TCF7L1	2	13	15	249.264
#469	CREBBP	2	13	15	339.984
#470	HOPX	2	14	16	1490.4
#471	CTCF	2	12	14	544.744
#472	SUPT4H1	2	10	12	480.917
#473	PFDN1	2	9	11	133.441
#474	FLI1	2	8	10	156.261
#475	EGR4	1	9	10	205.395
#476	ZNF236	1	11	12	475.878
#477	DLX1	1	10	11	182.349
#478	ZXDA	1	16	17	971.237
#479	STRN3	1	12	13	164.987
#480	TRERF1	1	12	13	105.007
#481	ZNF35	1	17	18	224.878
#482	HNF1B	1	18	19	792.743
#483	SPIB	1	8	9	1489.117
#484	ANKRD30A	1	13	14	127.199
#485	MYC	1	9	10	124.795
#486	NFATC3	1	9	10	179.682
#487	MEIS3P1	1	10	11	72.947
#488	ASCL1	1	14	15	340.71
#489	ZNF45	1	6	7	228.696
#490	ZRANB2	1	12	13	452.024
#491	NFYB	1	8	9	277.29
#492	ZSCAN12	1	12	13	4249.805
#493	ZNF70	1	12	13	245.804
#494	CREB3L2	1	14	15	160.517
#495	NR0B1	1	13	14	673.295
#496	DMRT2	0	11	11	0
#497	JDP2	0	7	7	0
#498	ATF4	0	13	13	0
#499	LCOR	0	11	11	0
#500	PITX1	0	9	9	0