Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	CREBBP	41	0	41	0
#2	ELK3	31	4	35	1748.397
#3	JUND	31	5	36	4374.111
#4	NKX2-1	30	2	32	535.72
#5	ALX3	30	6	36	4690.12
#6	TFE3	29	8	37	5536.292
#7	USF2	29	4	33	804.064
#8	CREB3	29	5	34	2104.256
#9	TAF10	26	4	30	1347.554
#10	GCFC1	26	5	31	1343.526
#11	SPDEF	25	7	32	894.872
#12	ZNF287	25	4	29	674.112
#13	HIF1A	24	7	31	3764.952
#14	ZNF80	24	3	27	882.647
#15	POU3F1	24	6	30	1462.874
#16	ESRRA	24	4	28	799.178
#17	ELK1	24	8	32	791.193
#18	NR3C2	24	5	29	3278.827
#19	ZNF45	23	7	30	1361.835
#20	ADNP2	23	8	31	2570.399
#21	CREB3L2	23	13	36	5276.534
#22	ZKSCAN1	22	4	26	654.827
#23	ZNF75D	22	8	30	2842.683
#24	HMGA1	22	9	31	2980.573
#25	ZEB1	22	4	26	785.597
#26	EDF1	22	4	26	598.889
#27	TFCP2L1	21	8	29	3136.24
#28	TCF7L1	21	5	26	1811.619
#29	TADA3	21	7	28	4510.077
#30	CBFB	21	7	28	2297.851
#31	RB1	21	10	31	2560.007
#32	MEOX2	21	4	25	4263.199
#33	ADNP	21	10	31	1932.487
#34	MMP14	21	6	27	1652.921
#35	TFEC	20	7	27	2441.165
#36	MLL	20	4	24	1351.418
#37	POU5F1B	20	5	25	1658.346
#38	ZNF167	20	3	23	474.433
#39	ZNF444	19	6	25	1591.351
#40	MAFB	19	5	24	2063.183
#41	REST	19	8	27	1442.617
#42	FOXP3	19	6	25	3016.558
#43	TAF7	18	5	23	1996.101
#44	GATA3	18	9	27	2558.818
#45	PPARD	18	9	27	3170.109
#46	SCAND1	18	3	21	546.483
#47	SLC30A9	18	4	22	1473.215
#48	LASS6	18	5	23	2625.122
#49	ONECUT2	17	7	24	1143.993
#50	HNRNPAB	17	8	25	3939.768
#51	PHF1	17	8	25	2023.188
#52	HSF2	17	6	23	501.823
#53	CDKN2A	17	6	23	1367.43
#54	MSRB2	17	6	23	1079.289
#55	TCF4	17	9	26	2067.917
#56	ATF3	17	0	17	0
#57	HNF1A	17	7	24	1428.817
#58	TCF21	16	3	19	271.069
#59	E2F4	16	6	22	533.405
#60	FUBP1	16	10	26	3070.19
#61	MEIS2	16	11	27	799.031
#62	ATF1	16	8	24	1321.825
#63	BACH1	16	10	26	2335.521
#64	NR1H4	16	7	23	2425.934
#65	THRA	16	10	26	2884.802
#66	KLF7	16	7	23	1334.647
#67	HOXB3	15	3	18	239.028
#68	ZNF639	15	7	22	3926.136
#69	RNF4	15	7	22	1558.257
#70	KLF12	15	9	24	2701.933
#71	SP3	15	5	20	511.117
#72	C2orf3	15	6	21	764.051
#73	HOXA10	15	9	24	1328.21
#74	GATAD2A	15	6	21	1318.266
#75	ZGPAT	15	9	24	2045.643
#76	ENO1	15	13	28	3307.264
#77	AATF	15	10	25	1257.995
#78	TCF7L2	15	8	23	1730.096
#79	MAFF	15	7	22	1511.471
#80	NFE2L1	15	7	22	1285.317
#81	TAF13	14	5	19	647.39
#82	CSRNP2	14	11	25	1864.84
#83	MSL3	14	3	17	742.248
#84	PPARA	14	5	19	256.887
#85	HSF4	14	11	25	2894.259
#86	KLF9	14	14	28	4468.456
#87	ETS2	14	4	18	557.181
#88	KDM5B	14	5	19	2105.378
#89	HNRNPK	14	12	26	4739.921
#90	NPAT	14	10	24	2835.905
#91	RXRB	14	9	23	1731.528
#92	NFE2L2	14	9	23	3899.184
#93	C11orf9	14	10	24	7463.95
#94	SLC2A4RG	14	8	22	2129.439
#95	POU2F1	14	7	21	2210.458
#96	NR3C1	14	8	22	2274.536
#97	RUNX1T1	13	9	22	784.497
#98	KDM5A	13	6	19	1551.642
#99	ZSCAN12	13	9	22	2157.887
#100	GABPA	13	9	22	3562.107
#101	ZNF155	13	8	21	1617.266
#102	ZNF175	13	6	19	1031.307
#103	MEF2C	13	7	20	857.941
#104	ARNT	13	7	20	908.264
#105	PLSCR1	13	9	22	4245.105
#106	IRF6	13	7	20	745.72
#107	MEF2A	13	5	18	820.731
#108	FOXC1	13	6	19	1236.582
#109	POU2F3	13	5	18	2104.175
#110	CREBZF	13	6	19	1824.048
#111	PPARG	13	8	21	4533.555
#112	ERF	13	7	20	1037.335
#113	TRIM22	13	7	20	1054.522
#114	RFXANK	13	10	23	737.194
#115	IRF5	13	9	22	2406.971
#116	MNT	13	5	18	1207.038
#117	TCF25	12	6	18	2717.014
#118	SMAD6	12	10	22	832.615
#119	NR1H2	12	9	21	1752.559
#120	CTBP1	12	8	20	974.278
#121	MBD1	12	10	22	4501.731
#122	MLLT10	12	3	15	3947.544
#123	GATA4	12	4	16	386.914
#124	ZKSCAN4	12	7	19	665.505
#125	SIM1	12	7	19	1394.892
#126	TGIF1	12	7	19	1202.142
#127	RELA	12	10	22	842.178
#128	MEIS3P1	12	11	23	1566.662
#129	ZNF207	12	7	19	4050.233
#130	KLF4	12	11	23	1572.95
#131	ZNF148	12	8	20	1097.539
#132	XBP1	12	11	23	3305.128
#133	AR	12	6	18	2219.928
#134	TCF20	12	9	21	2476.443
#135	MITF	12	6	18	1784.423
#136	TBX6	12	10	22	3680.018
#137	SUPT4H1	12	8	20	1391.883
#138	ZKSCAN3	11	8	19	2890.388
#139	MECOM	11	9	20	1537.469
#140	ZNF236	11	8	19	1245.957
#141	STAT3	11	9	20	1687.06
#142	SOX15	11	7	18	826.037
#143	CITED2	11	8	19	865.507
#144	E2F3	11	10	21	1948.68
#145	TRPS1	11	8	19	2117.981
#146	MYBL2	11	3	14	351.547
#147	GTF2H3	11	5	16	644.25
#148	SOX4	11	7	18	2670.816
#149	TFAP2C	11	12	23	11511.258
#150	ZNF91	11	10	21	1855.816
#151	PBX1	11	7	18	1811.411
#152	HOXD9	11	9	20	1142.448
#153	HOXB5	11	13	24	4816.187
#154	WT1	11	10	21	2703.464
#155	PLAG1	11	10	21	1624.441
#156	CEBPD	11	12	23	1313.527
#157	EGR1	11	5	16	505.967
#158	BLZF1	11	10	21	1770.487
#159	ECSIT	10	10	20	700.822
#160	HOXC10	10	6	16	663.355
#161	CNBP	10	9	19	1224.641
#162	NKX3-1	10	6	16	1525.937
#163	NR1H3	10	9	19	3646.233
#164	ESRRG	10	14	24	3010.652
#165	ERG	10	3	13	277.353
#166	IRF7	10	8	18	961.567
#167	BHLHE40	10	8	18	1374.575
#168	FOXO4	10	9	19	371.259
#169	PA2G4	10	7	17	3131.917
#170	STRN3	10	10	20	1245.859
#171	SCMH1	10	8	18	1550.681
#172	HOXC4	10	7	17	871.783
#173	SOX11	10	4	14	320.048
#174	MYC	10	8	18	1814.171
#175	E4F1	10	10	20	1406.006
#176	LZTS1	10	11	21	6575.946
#177	SIM2	10	12	22	2914.971
#178	SP140	10	9	19	2425.152
#179	KLF10	10	8	18	1052.228
#180	OLIG2	10	4	14	1142.225
#181	AHR	9	11	20	2493.427
#182	ZSCAN16	9	14	23	2247.414
#183	NFYB	9	12	21	2139.624
#184	ZNF274	9	8	17	1466.705
#185	IKZF1	9	6	15	1137.268
#186	CTNNB1	9	6	15	803.289
#187	TAL1	9	7	16	681.882
#188	CREB1	9	6	15	605.662
#189	NPAS1	9	6	15	353.703
#190	RUNX1	9	12	21	3257.634
#191	SATB2	9	10	19	2016.785
#192	FOSB	9	8	17	377.741
#193	SCAND2	9	3	12	152.381
#194	ELF4	9	11	20	905.027
#195	BHLHE41	9	10	19	1385.623
#196	HMGB1	9	8	17	2201.667
#197	TCF3	9	12	21	4556.358
#198	ATF6B	9	10	19	1514.584
#199	MAF	9	7	16	884.007
#200	NFIL3	9	3	12	293.674
#201	EPAS1	9	9	18	450.401
#202	ATF5	9	8	17	1464.561
#203	RFX5	9	14	23	2391.251
#204	NR5A2	9	3	12	231.624
#205	CREBL2	9	8	17	1384.723
#206	SOX9	9	8	17	1071.751
#207	NR2C1	9	11	20	2692.613
#208	ZNF140	9	14	23	2351.237
#209	SATB1	9	5	14	868.835
#210	RERE	9	7	16	878.54
#211	TBX1	9	3	12	306.133
#212	MGA	9	9	18	725.341
#213	TAF6	9	9	18	4328.514
#214	MLXIPL	8	14	22	1949.841
#215	DMTF1	8	8	16	915.61
#216	AHCTF1	8	10	18	1781.561
#217	MYCN	8	8	16	1236.696
#218	RCOR1	8	12	20	1581.86
#219	TCF7	8	9	17	1665.17
#220	HOXD13	8	3	11	187.203
#221	ZNF434	8	6	14	574.497
#222	HOXD1	8	11	19	2976.073
#223	NFIB	8	13	21	2342.143
#224	LMO4	8	8	16	1242.535
#225	KLF11	8	13	21	2822.69
#226	NFE2L3	8	13	21	905.886
#227	ZNF81	8	6	14	1656.518
#228	KLF2	8	16	24	1559.057
#229	TBX3	8	6	14	103.158
#230	BCL6	8	7	15	1271.005
#231	ESR1	8	10	18	924.126
#232	GRHL2	8	6	14	1694.345
#233	E2F1	8	6	14	395.204
#234	NR4A3	8	10	18	2271.207
#235	BTG2	8	4	12	640.404
#236	STAT5A	8	7	15	1055.095
#237	ETV7	8	7	15	1169.324
#238	RUNX3	8	2	10	1523.386
#239	RARG	8	7	15	904.496
#240	HNF1B	8	4	12	204.299
#241	CSDA	8	9	17	1223.764
#242	NOTCH1	8	8	16	892.692
#243	UBN1	8	11	19	2966.528
#244	SMAD5	7	12	19	1817.655
#245	ALX1	7	5	12	604.43
#246	FOXL1	7	7	14	1126.554
#247	HMG20B	7	8	15	370.511
#248	ETV2	7	12	19	1091.474
#249	HOXA4	7	9	16	594.754
#250	TFAP4	7	6	13	308.688
#251	ELF2	7	14	21	2049.592
#252	EMX1	7	10	17	3085.074
#253	EGR2	7	8	15	278.006
#254	SOX13	7	12	19	965.582
#255	RCAN1	7	12	19	1893.8
#256	GLI3	7	7	14	540.594
#257	RORA	7	12	19	2019.887
#258	MEIS1	7	10	17	1826.442
#259	PRRX2	7	9	16	793.448
#260	TGIF2	7	10	17	952.88
#261	KLF5	7	15	22	2319.959
#262	HNF4G	7	6	13	708.35
#263	SALL1	7	7	14	991.799
#264	HOXA6	7	5	12	810.13
#265	ZBTB48	7	9	16	2989.077
#266	ZNF500	7	13	20	707.813
#267	ZNF157	7	6	13	905.992
#268	BTAF1	7	11	18	1037.147
#269	ZNF197	7	7	14	1002.158
#270	ZNF217	7	12	19	1077.866
#271	ZXDC	7	9	16	670.008
#272	MYNN	7	9	16	713.855
#273	EGR3	7	8	15	555.404
#274	SNAPC4	7	11	18	1133.763
#275	AEBP1	7	12	19	2932.262
#276	TSC22D1	7	10	17	1038.507
#277	TCF12	7	7	14	257.994
#278	ZNF33B	7	9	16	4160.711
#279	FOXO3	7	9	16	1464.571
#280	CUX1	7	10	17	2133.765
#281	TFDP2	7	10	17	934.091
#282	LHX1	6	9	15	230.835
#283	FOS	6	6	12	157.434
#284	JUNB	6	13	19	972.199
#285	ZFPM2	6	9	15	283.962
#286	SCML1	6	6	12	340.827
#287	TFAP2A	6	8	14	635.792
#288	ZEB2	6	12	18	646.564
#289	NPAS2	6	14	20	3439.378
#290	VDR	6	13	19	326.735
#291	CEBPB	6	6	12	371.516
#292	PEG3	6	13	19	1805.392
#293	HOXA5	6	6	12	537.903
#294	FBXW7	6	9	15	1019.48
#295	PBX2	6	8	14	784.36
#296	IRX5	6	8	14	2095.885
#297	RARB	6	7	13	403.387
#298	NFYA	6	6	12	822.123
#299	PITX2	6	7	13	648.792
#300	TEAD1	6	9	15	1109.875
#301	CNOT7	6	6	12	899.02
#302	YEATS4	6	10	16	620.714
#303	SRF	6	17	23	1537.178
#304	EVX1	6	9	15	1291.159
#305	IRF3	6	11	17	2042.768
#306	TP53	6	11	17	1986.692
#307	HOXC8	6	11	17	979.726
#308	POU1F1	6	9	15	322.354
#309	SALL2	6	9	15	1595.095
#310	CITED1	6	5	11	2346.889
#311	NR2E3	6	5	11	162.722
#312	REXO4	6	7	13	371.563
#313	NR2F6	6	9	15	768.792
#314	HOXD11	6	11	17	3788.155
#315	ZNF219	6	8	14	619.423
#316	ZFP36L1	5	11	16	2304.714
#317	ZNF3	5	9	14	604.806
#318	TARDBP	5	14	19	776.111
#319	ELK4	5	8	13	951.885
#320	NFYC	5	9	14	2072.546
#321	ZNF24	5	10	15	323.226
#322	ZNF187	5	11	16	524.773
#323	HOXA7	5	10	15	1257.894
#324	HOXC13	5	6	11	349.296
#325	MZF1	5	11	16	679.851
#326	NR4A1	5	10	15	930.333
#327	KLF6	5	8	13	958.745
#328	IRF9	5	11	16	4020.789
#329	ZNF263	5	6	11	293.671
#330	ZNF165	5	8	13	1011.791
#331	ZNF133	5	6	11	289.651
#332	NFATC3	5	12	17	2432.125
#333	BUD31	5	9	14	427.595
#334	TCEAL1	5	8	13	910.462
#335	NFATC1	5	15	20	1441.927
#336	TEAD4	5	11	16	2416.047
#337	TSC22D2	5	16	21	1796.13
#338	NANOG	5	5	10	1235.204
#339	NFAT5	5	10	15	541.355
#340	HCLS1	5	10	15	1005.119
#341	PURA	5	10	15	606.41
#342	ZNF277	5	3	8	250.571
#343	NR2F2	5	13	18	534.972
#344	FOXJ2	4	11	15	1110.979
#345	NOLC1	4	5	9	231.617
#346	TBP	4	9	13	621.118
#347	ZKSCAN5	4	9	13	743.218
#348	ZNF93	4	9	13	1040.171
#349	ELF3	4	14	18	1350.702
#350	ZNF268	4	8	12	1172.274
#351	TULP4	4	11	15	142.875
#352	PAX8	4	13	17	2212.487
#353	TEAD3	4	13	17	1386.053
#354	GABPB1	4	12	16	2795.602
#355	PTTG1	4	9	13	1253.098
#356	RXRA	4	11	15	1220.064
#357	NR1D2	4	14	18	1833.264
#358	GCM1	4	8	12	434.269
#359	HOXA1	4	12	16	195.914
#360	TAF4	4	5	9	296.475
#361	MLX	4	8	12	365.522
#362	YY1	4	10	14	1935.835
#363	ZNF35	4	6	10	852.111
#364	RBPJ	4	9	13	1826.014
#365	ZNF189	4	9	13	131.114
#366	HOXB6	4	11	15	1291.586
#367	POU6F1	4	5	9	407.875
#368	SMAD2	4	8	12	1289.267
#369	HLF	4	15	19	993.431
#370	NFKB1	4	10	14	1133.215
#371	LASS2	4	11	15	294.938
#372	ATF6	4	11	15	2465.297
#373	PCGF2	4	11	15	2357.475
#374	RARA	4	5	9	470.446
#375	NRL	4	10	14	1431.211
#376	ZNF394	4	11	15	657.064
#377	DMRT1	4	7	11	376.522
#378	PHTF1	4	10	14	1821.571
#379	ST18	4	10	14	1189.695
#380	STAT4	4	4	8	737.476
#381	HOXD3	4	4	8	209.049
#382	SREBF2	4	7	11	1276.66
#383	MEF2D	4	7	11	103.231
#384	IRF8	4	6	10	255.476
#385	RAX	4	5	9	444.923
#386	SNAPC5	4	6	10	337.887
#387	HMGB2	4	10	14	1592.177
#388	TSC22D3	4	11	15	674.083
#389	TAF1B	4	7	11	1102.732
#390	GTF2I	4	8	12	1304.272
#391	SMAD4	4	12	16	606.711
#392	TFEB	4	11	15	2360.782
#393	FOXJ3	4	7	11	858.465
#394	SIX2	3	14	17	1185.021
#395	MTA1	3	11	14	1225.055
#396	SREBF1	3	12	15	779.982
#397	TFCP2	3	6	9	91.006
#398	ATF4	3	15	18	2558.388
#399	NFATC4	3	8	11	160.855
#400	HHEX	3	8	11	521.955
#401	CEBPA	3	13	16	1446.925
#402	CLOCK	3	9	12	689.717
#403	MSX2	3	2	5	138.851
#404	SMAD3	3	14	17	2609.067
#405	FOXE1	3	5	8	900.238
#406	FOXN3	3	13	16	578.737
#407	RBCK1	3	10	13	998.729
#408	ZNF202	3	9	12	282.287
#409	SUPT6H	3	9	12	925.274
#410	E2F6	3	6	9	712.039
#411	HNF4A	3	6	9	522.864
#412	SCML2	3	10	13	132.422
#413	FOSL2	3	11	14	371.914
#414	ETV1	3	13	16	315.665
#415	CNOT8	3	12	15	1150.193
#416	FOSL1	3	6	9	825.35
#417	TRIM28	3	14	17	653.267
#418	SMAD1	3	9	12	903.168
#419	MYF5	3	3	6	96.323
#420	LZTR1	3	9	12	507.614
#421	YBX1	3	13	16	1751.883
#422	GAS7	3	14	17	2690.583
#423	NR4A2	2	8	10	775.985
#424	EHF	2	7	9	1136.443
#425	EGR4	2	9	11	89.944
#426	PKNOX1	2	10	12	674.951
#427	ZFP36L2	2	12	14	1908.8
#428	ZBTB38	2	14	16	2670.455
#429	TBX2	2	10	12	835.303
#430	TFAM	2	14	16	1102.984
#431	DDIT3	2	14	16	318.532
#432	MSX1	2	11	13	795.728
#433	HOXB2	2	11	13	1408.888
#434	DRAP1	2	9	11	283.851
#435	ARID4A	2	11	13	345.622
#436	HMG20A	2	12	14	1200.418
#437	PRDM2	2	12	14	1534.858
#438	ZNF83	2	11	13	204.171
#439	ZSCAN18	2	8	10	608.285
#440	TWIST1	2	10	12	915.915
#441	ZBTB17	2	8	10	672.639
#442	HIF3A	2	10	12	672.548
#443	TAF5	2	15	17	572.85
#444	HES1	2	14	16	185.404
#445	SLC26A3	2	8	10	1296.955
#446	BCL3	2	13	15	546.842
#447	TCFL5	2	12	14	195.45
#448	BCL11B	2	11	13	1980.325
#449	STAT1	2	13	15	205.793
#450	ELF1	2	10	12	147.583
#451	IRF1	2	16	18	2118.085
#452	MEOX1	2	7	9	70.817
#453	JUN	2	11	13	280.942
#454	FOXD1	2	10	12	102.554
#455	SNAI2	2	9	11	39.154
#456	FOXA2	2	4	6	80.747
#457	GTF2H4	2	7	9	506.158
#458	HEY2	2	9	11	652.478
#459	ZNF131	1	10	11	214.268
#460	LHX3	1	4	5	7.002
#461	HEY1	1	16	17	611.379
#462	HOPX	1	15	16	631.353
#463	SPEN	1	13	14	441.348
#464	GATAD1	1	9	10	223.588
#465	HIRA	1	12	13	955.115
#466	NFIC	1	8	9	291.163
#467	NR2F1	1	9	10	177.832
#468	FLI1	1	17	18	1749.132
#469	GATA2	1	9	10	558.961
#470	MTF1	1	10	11	201.935
#471	ZNF135	1	7	8	381.676
#472	GATA6	1	11	12	943.265
#473	ZNF238	1	7	8	186.577
#474	HMBOX1	1	9	10	50.704
#475	PBX3	1	11	12	74.933
#476	HOXA9	1	11	12	755.349
#477	SOX30	1	6	7	203.683
#478	DBP	1	10	11	53.73
#479	BNC1	1	6	7	407.208
#480	LEF1	1	15	16	320.99
#481	TFAP2B	1	11	12	169.541
#482	RUNX2	1	4	5	89.427
#483	FOXO1	1	9	10	68.828
#484	ZNF323	1	5	6	173.02
#485	HOXB7	1	15	16	728.912
#486	ZNF174	1	8	9	292.099
#487	CREM	1	14	15	327.893
#488	ZNF281	1	8	9	34.439
#489	MYCL1	0	7	7	0
#490	ETV5	0	13	13	0
#491	ARNTL	0	10	10	0
#492	NR1I3	0	9	9	0
#493	PLAGL2	0	10	10	0
#494	MAX	0	12	12	0
#495	ARNT2	0	11	11	0
#496	ZHX3	0	11	11	0
#497	TFDP1	0	14	14	0
#498	ELF5	0	16	16	0
#499	CSRNP3	0	7	7	0
#500	WNT5A	0	13	13	0