Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TCF4	40	4	44	3293.507
#2	YBX1	39	1	40	52.316
#3	BCL3	32	4	36	3555.757
#4	ZNF45	29	3	32	172.899
#5	GTF2H3	28	1	29	700.857
#6	CEBPA	28	6	34	1254.767
#7	HCLS1	27	4	31	395.919
#8	HOPX	25	3	28	2568.115
#9	PBX1	25	6	31	1897.979
#10	ZNF148	24	3	27	1251.104
#11	NFYB	23	5	28	1016.739
#12	KLF4	22	3	25	2854.995
#13	CEBPD	22	11	33	4155.616
#14	RXRA	21	11	32	3150.174
#15	KLF10	21	6	27	621.891
#16	ZFP36L1	21	6	27	1088.182
#17	RBPJ	21	8	29	920.008
#18	MLLT10	20	5	25	780.642
#19	SRF	20	7	27	3233.824
#20	TP63	20	2	22	161.287
#21	BACH1	19	5	24	2722.118
#22	REST	19	4	23	817.413
#23	ATF6	19	7	26	683.262
#24	PAX8	19	8	27	2658.337
#25	TCF7	19	5	24	1565.598
#26	MAF	19	8	27	2320.766
#27	NOTCH1	18	9	27	1921.434
#28	TRPS1	18	11	29	3615.455
#29	FBXW7	18	8	26	4241.633
#30	POU3F3	18	5	23	466.824
#31	ZEB1	18	11	29	1879.728
#32	RCOR1	17	8	25	1615.258
#33	C2orf3	17	5	22	723.369
#34	SPI1	17	5	22	920.261
#35	PAX3	17	5	22	3226.675
#36	STRN3	17	5	22	1063.675
#37	ETV1	17	9	26	3914.166
#38	TFDP1	17	8	25	2005.294
#39	GAS7	17	9	26	1434.227
#40	ENO1	17	6	23	3731.355
#41	RUNX1T1	17	5	22	2845.184
#42	YY1	17	6	23	1647.546
#43	TRIM29	17	0	17	0
#44	IRF1	17	6	23	884.966
#45	FOXN3	17	9	26	4834.031
#46	MLX	16	6	22	795.678
#47	BCL11B	16	1	17	17.914
#48	MITF	16	14	30	2630.848
#49	PURA	16	13	29	3716.925
#50	ZNF175	16	1	17	114.484
#51	ZNF24	16	7	23	2677.062
#52	ESR2	16	7	23	1616.201
#53	TCEAL1	16	10	26	2669.458
#54	DBP	16	4	20	281.601
#55	BCL6	15	8	23	3189.78
#56	EGR2	15	7	22	1059.198
#57	ELF4	15	9	24	4854.209
#58	SMAD1	15	10	25	2908.585
#59	ERG	15	5	20	228.64
#60	FOXC1	15	6	21	3625.687
#61	KLF5	15	13	28	3431.239
#62	HOXC8	15	3	18	104.547
#63	ZKSCAN5	15	11	26	2747.732
#64	NR5A1	15	6	21	1483.237
#65	HMG20A	15	11	26	3223.514
#66	IRF6	15	4	19	1071.304
#67	ATF1	15	8	23	2811.728
#68	PRRX2	15	5	20	786.43
#69	NR3C1	14	11	25	2324.736
#70	GRHL2	14	3	17	80.971
#71	LMX1B	14	6	20	449.66
#72	HOXB1	14	1	15	234.782
#73	MTA2	14	2	16	131.303
#74	FOXJ2	14	8	22	2419.069
#75	ZNF263	14	7	21	1054.836
#76	GBX2	14	5	19	828.867
#77	MEOX2	14	7	21	7518.476
#78	SPEN	14	4	18	354.759
#79	RORA	14	5	19	263.153
#80	ZFP36L2	14	13	27	2095.59
#81	ZNF192	14	6	20	2164.27
#82	BTAF1	14	6	20	317.009
#83	RFX5	14	6	20	1002.011
#84	PBX2	14	5	19	3281.489
#85	FOXO1	14	9	23	2593.257
#86	USF2	14	10	24	1184.154
#87	POU2F1	14	5	19	668.989
#88	E2F6	14	9	23	2239.522
#89	FUBP1	14	10	24	5275.574
#90	E2F1	14	6	20	1422.902
#91	KLF7	14	7	21	359.634
#92	ALX1	13	8	21	2344.42
#93	PBX3	13	9	22	3448.42
#94	NFYC	13	4	17	521.323
#95	ELK3	13	11	24	2166.299
#96	SPDEF	13	2	15	1010.512
#97	MNX1	13	2	15	60.544
#98	DLX2	13	2	15	38.536
#99	FOXP3	13	4	17	1385.229
#100	CIR1	13	8	21	1577.075
#101	ZNF274	13	3	16	822.536
#102	TFAP2A	13	10	23	2386.657
#103	EGR1	13	8	21	1075.401
#104	FOXE1	13	1	14	27.916
#105	SOX13	13	8	21	2532.431
#106	SMAD9	13	4	17	2147.153
#107	SOX15	12	0	12	0
#108	MAFB	12	10	22	2133.752
#109	BNC1	12	9	21	892.93
#110	FOXN1	12	5	17	693.816
#111	TRIM22	12	11	23	1467.877
#112	MLL	12	5	17	299.393
#113	CREB3L1	12	6	18	1288.863
#114	HOXB2	12	8	20	1093.593
#115	ETS2	12	11	23	942.91
#116	MYT1L	12	8	20	2941.99
#117	KLF2	12	8	20	1144.406
#118	ZNF140	12	12	24	1621.698
#119	HMX1	12	5	17	1626.598
#120	ARNT2	12	7	19	3808.238
#121	PA2G4	11	14	25	3646.452
#122	HOXD3	11	6	17	422.763
#123	SIM1	11	6	17	497.459
#124	NFATC3	11	9	20	1441.376
#125	THRA	11	10	21	1355.781
#126	ZNF93	11	7	18	1256.512
#127	FOXM1	11	8	19	3527.322
#128	ZIC3	11	4	15	255.918
#129	STAT4	11	5	16	414.063
#130	IRF8	11	5	16	953.358
#131	PLSCR1	11	5	16	621.482
#132	SOX9	11	16	27	2834.018
#133	HLF	11	4	15	64.808
#134	PCGF2	11	9	20	2517.439
#135	HNF1B	11	9	20	1461.122
#136	GABPA	11	6	17	1150.133
#137	RB1	11	10	21	1394.146
#138	RUNX1	11	10	21	3579.766
#139	ELK1	11	12	23	2286.491
#140	MZF1	11	9	20	2700.536
#141	EHF	11	10	21	5493.416
#142	SNAI2	11	11	22	2840.006
#143	NFE2L3	11	8	19	1176.096
#144	ETV4	10	5	15	1226.381
#145	ELF2	10	9	19	1608.356
#146	IRX4	10	8	18	697.828
#147	ESRRA	10	9	19	1266.117
#148	ZFHX3	10	8	18	1843.875
#149	MSL3	10	8	18	513.646
#150	CITED2	10	12	22	1860.966
#151	SOX10	10	5	15	689.154
#152	HAND1	10	2	12	295.845
#153	POU2F3	10	7	17	326.429
#154	AHCTF1	10	8	18	1370.013
#155	SATB1	10	13	23	1841.308
#156	ADNP	10	10	20	1775.181
#157	HEY1	10	12	22	2253.634
#158	EGR3	10	15	25	3093.698
#159	TCF20	10	12	22	2738.844
#160	HR	10	11	21	1081.708
#161	LASS2	10	5	15	642.165
#162	PKNOX1	10	10	20	1516.342
#163	TFE3	10	8	18	1221.693
#164	GABPB1	10	11	21	2066.708
#165	ARNTL	9	9	18	1958.146
#166	NR1H3	9	7	16	933.991
#167	MEF2A	9	5	14	444.008
#168	ZNF217	9	11	20	1722.646
#169	AFF1	9	10	19	1004.505
#170	TEAD4	9	6	15	2145.04
#171	CLOCK	9	5	14	459.09
#172	YEATS4	9	13	22	2314.136
#173	SMAD4	9	10	19	675.185
#174	ZNF323	9	10	19	2827.43
#175	TFAP2C	9	11	20	972.664
#176	KLF6	9	11	20	3537.872
#177	GCFC1	9	8	17	1557.545
#178	KLF12	9	11	20	928.353
#179	SOX4	9	14	23	1909.28
#180	ZKSCAN1	9	11	20	1184.468
#181	TEAD1	9	5	14	1516.179
#182	ELF1	9	11	20	1666.526
#183	ZNF281	9	7	16	2054.209
#184	PKNOX2	9	7	16	637.411
#185	ZNF193	9	7	16	2373.368
#186	HIC1	9	4	13	355.079
#187	VDR	9	9	18	1162.41
#188	AHR	9	12	21	2851.649
#189	GATA3	9	7	16	143.454
#190	NPAT	9	6	15	2947.799
#191	HSF1	9	11	20	3143.334
#192	RFX3	9	9	18	1544.806
#193	SATB2	9	10	19	2525.341
#194	NR4A3	9	10	19	1319.221
#195	TRIM28	9	9	18	716.666
#196	NR1H2	9	7	16	2488.652
#197	AEBP1	9	10	19	3587.113
#198	FOXO4	9	3	12	1891.551
#199	SREBF2	8	11	19	1096.794
#200	SIX5	8	9	17	1002.452
#201	ZNF207	8	8	16	849.391
#202	DRAP1	8	7	15	1518.73
#203	CREB1	8	8	16	845.605
#204	NFAT5	8	6	14	2438.785
#205	NR4A2	8	15	23	2783.372
#206	ZNF75D	8	6	14	1682.153
#207	CREM	8	7	15	972.132
#208	ETV5	8	11	19	1867.605
#209	TSC22D1	8	11	19	2428.697
#210	ZNF3	8	7	15	1530.907
#211	RXRG	8	12	20	2945.317
#212	MTF1	8	8	16	886.371
#213	SOX12	8	8	16	1099.312
#214	CREBBP	8	9	17	4276.04
#215	TCFL5	8	11	19	1075.692
#216	MEF2D	8	4	12	120.677
#217	TSC22D3	8	7	15	700.996
#218	MEF2C	8	7	15	794.739
#219	MMP14	8	9	17	1440.308
#220	DDIT3	8	13	21	1583.363
#221	ZNF133	8	6	14	1741.458
#222	POU3F1	8	9	17	1291.649
#223	CREBL2	8	10	18	2272.321
#224	TADA3	8	4	12	576.322
#225	TFAM	8	9	17	970.073
#226	STAT5B	8	6	14	731.883
#227	HMGA1	8	6	14	1322.387
#228	TBP	8	7	15	556.414
#229	TCF7L2	8	7	15	1404.991
#230	HSF4	8	4	12	518.096
#231	STAT2	8	11	19	3184.267
#232	BUD31	8	12	20	2069.918
#233	OLIG2	8	7	15	1079.347
#234	TFDP2	8	14	22	1400.713
#235	CREB3L2	7	10	17	1973.319
#236	GTF2I	7	11	18	3583.379
#237	STAT6	7	9	16	1215.742
#238	HSF2	7	7	14	405.815
#239	MECOM	7	6	13	865.933
#240	FOSL1	7	7	14	907.804
#241	XBP1	7	11	18	2627.009
#242	EDF1	7	5	12	1182.081
#243	HIRA	7	12	19	1904.717
#244	TCF25	7	7	14	1288.43
#245	HOXA11	7	10	17	2137.984
#246	MAFG	7	5	12	431.19
#247	ARNTL2	7	6	13	436.922
#248	NR2F2	7	13	20	1402.222
#249	MSRB2	7	17	24	2980.836
#250	HOXD13	7	14	21	2637.201
#251	HIF3A	7	7	14	614.289
#252	HOXB7	7	10	17	3423.057
#253	SMAD2	7	4	11	253.286
#254	ZHX2	7	8	15	1638.96
#255	CNOT8	7	6	13	619.91
#256	IRX5	7	10	17	1695.177
#257	PTTG1	7	7	14	720.84
#258	ZSCAN12	7	5	12	397.48
#259	POU6F2	7	6	13	321.205
#260	LEF1	7	15	22	2257.814
#261	SP3	7	11	18	1160.67
#262	NR0B1	7	10	17	1449.126
#263	PHTF1	7	12	19	600.975
#264	REL	7	8	15	932.134
#265	SCAND1	7	12	19	1163.33
#266	NPAS2	7	10	17	1330.147
#267	TBX3	7	12	19	1719.704
#268	NOLC1	7	9	16	637.035
#269	MAX	7	9	16	1192.253
#270	HDAC2	7	7	14	765.153
#271	SOX2	7	10	17	1712.976
#272	HMGB2	6	12	18	2438.056
#273	HMGA2	6	15	21	1619.201
#274	ZSCAN18	6	14	20	1568.966
#275	PEG3	6	15	21	5489.604
#276	NFIB	6	8	14	776.23
#277	NR2F1	6	13	19	2825.926
#278	LZTS1	6	9	15	1991.157
#279	FOXF1	6	9	15	1044.614
#280	TBX2	6	10	16	1156.688
#281	ZNF83	6	8	14	1904.191
#282	HHEX	6	10	16	1065.249
#283	KLF9	6	11	17	1218.597
#284	MEIS3P1	6	9	15	825.528
#285	HOXA5	6	8	14	969.292
#286	ZNF91	6	8	14	647.049
#287	ZBTB38	6	9	15	977.477
#288	FOXO3	6	17	23	1058.975
#289	MEIS2	6	13	19	3731.307
#290	CBFB	6	8	14	1298.9
#291	TULP4	6	9	15	1847.719
#292	GATAD1	6	12	18	643.383
#293	FOXF2	6	10	16	4482.88
#294	E2F5	6	11	17	2068.506
#295	BACH2	6	11	17	898.789
#296	EN1	6	9	15	729.27
#297	GATA6	6	14	20	1294.281
#298	C11orf9	6	11	17	2137.465
#299	TFEC	6	9	15	1827.2
#300	STAT3	6	14	20	1289.668
#301	ZNF165	6	11	17	1199.561
#302	CEBPB	6	10	16	668.514
#303	CUX1	6	11	17	1447.724
#304	ATF5	6	6	12	147.472
#305	ADNP2	6	9	15	2225.293
#306	HMBOX1	6	11	17	826.958
#307	RERE	6	7	13	659.601
#308	ZNF268	6	11	17	1149.477
#309	ATF4	6	6	12	1015.035
#310	MYBL2	6	11	17	2548.596
#311	HDAC1	6	11	17	1315.968
#312	KLF11	6	10	16	698.593
#313	KLF3	6	6	12	1203.097
#314	HOXB5	6	9	15	1189.254
#315	ST18	6	5	11	310.755
#316	IRF3	6	7	13	2342.533
#317	TBR1	6	12	18	2756.372
#318	TGIF2	6	8	14	922.874
#319	ELF3	6	6	12	430.227
#320	HAND2	6	5	11	249.253
#321	ESR1	6	5	11	163.198
#322	ZNF81	6	8	14	811.92
#323	BATF	6	8	14	903.645
#324	SLC30A9	6	10	16	937.05
#325	TCF21	6	6	12	775.521
#326	SNAPC4	6	7	13	1063.362
#327	ZFPM2	5	12	17	2684.712
#328	NFX1	5	7	12	371.252
#329	E2F8	5	7	12	2016.761
#330	SOLH	5	10	15	1014.212
#331	TAF10	5	11	16	970.849
#332	BTG2	5	8	13	427.997
#333	STAT5A	5	9	14	831.279
#334	NFE2L2	5	12	17	2047.122
#335	JUND	5	10	15	1036.102
#336	HOXA1	5	9	14	1111.909
#337	ARID4A	5	12	17	778.024
#338	HOXD1	5	6	11	1664.819
#339	FOSL2	5	10	15	1380.325
#340	ATF6B	5	5	10	1151.01
#341	IRF2	5	16	21	2183.672
#342	LASS6	5	11	16	1023.846
#343	SCAND2	5	5	10	142.289
#344	JUNB	5	11	16	428.154
#345	SOX11	5	8	13	941.726
#346	LMO4	5	12	17	731.104
#347	ATF3	5	10	15	2265.002
#348	GATAD2A	5	8	13	883.313
#349	SOX18	5	6	11	372.411
#350	PHF1	5	7	12	2954.33
#351	FOSB	5	8	13	406.806
#352	NCOR1	5	5	10	860.059
#353	ARNT	5	9	14	1501.806
#354	PITX1	5	8	13	651.521
#355	MYCL1	5	7	12	274.122
#356	ZNF174	5	5	10	215.322
#357	RUNX3	5	19	24	1730.549
#358	TFAP2B	5	7	12	1452.743
#359	JUN	5	9	14	711.975
#360	WNT5A	5	14	19	2825.588
#361	ZEB2	5	12	17	1662.492
#362	PLAGL2	5	4	9	124.31
#363	SOX5	5	10	15	962.255
#364	HEYL	5	8	13	1582.688
#365	MEIS1	5	7	12	638.612
#366	TEAD3	5	10	15	340.693
#367	UBP1	5	12	17	813.331
#368	TCF3	5	12	17	1620.056
#369	NR2C1	5	7	12	2485.521
#370	TLX2	5	11	16	416.556
#371	ZBTB17	5	4	9	18.321
#372	ZNF187	5	7	12	291.793
#373	HIF1A	4	3	7	364.303
#374	GTF2IRD1	4	10	14	704.48
#375	E2F3	4	7	11	875.253
#376	TSC22D4	4	9	13	559.298
#377	SLC2A4RG	4	12	16	1124.475
#378	RARA	4	4	8	121.983
#379	IRF4	4	12	16	1215.807
#380	DMTF1	4	6	10	388.455
#381	TCF15	4	7	11	693.831
#382	GTF2H4	4	8	12	641.859
#383	ZNF131	4	8	12	760.797
#384	SREBF1	4	12	16	1388.513
#385	ZNF238	4	14	18	857.55
#386	BHLHE40	4	13	17	1000.535
#387	CREBZF	4	12	16	560.893
#388	NKX3-2	4	7	11	379.324
#389	LHX2	4	9	13	810.559
#390	HOXB6	4	11	15	873.589
#391	IKZF1	4	10	14	1048.876
#392	TCF12	4	15	19	2432.94
#393	ERF	4	4	8	1194.348
#394	HMG20B	4	11	15	1586.494
#395	FOS	4	16	20	1242.336
#396	FLI1	4	8	12	290.796
#397	HNF4A	4	6	10	250.172
#398	EN2	4	8	12	778.385
#399	POU3F2	4	8	12	1057.085
#400	IRF9	4	5	9	325.26
#401	NFE2L1	4	8	12	454.278
#402	NR2F6	4	5	9	616.83
#403	FOXK2	4	8	12	704.969
#404	TWIST1	4	16	20	1613.65
#405	POU4F1	4	12	16	784.365
#406	TFCP2	4	5	9	536.773
#407	SNAPC5	4	9	13	786.351
#408	MTA1	4	8	12	1362.446
#409	HOXC4	4	6	10	732.441
#410	CITED1	4	15	19	3968.155
#411	ZIC1	4	15	19	2621.862
#412	NFATC1	4	8	12	760.054
#413	UBN1	4	13	17	1588.07
#414	CTCF	4	12	16	893.905
#415	PITX2	4	9	13	1504.869
#416	HOXA10	3	12	15	1787.545
#417	MYCN	3	12	15	1024.245
#418	SMAD3	3	8	11	667.13
#419	TAF7	3	9	12	625.492
#420	CDKN2A	3	10	13	1244.579
#421	STAT1	3	13	16	1857.835
#422	GSC2	3	7	10	1241.982
#423	TARDBP	3	10	13	1092.898
#424	SCML1	3	9	12	540.015
#425	CTNNB1	3	11	14	274.073
#426	KDM5A	3	11	14	686.177
#427	NR1D2	3	11	14	686.717
#428	KDM5B	3	8	11	916.772
#429	CTBP1	3	13	16	1815.615
#430	MSX1	3	9	12	677.395
#431	MAFF	3	12	15	979.102
#432	TAF1B	3	11	14	430.407
#433	SCML2	3	5	8	420.765
#434	BRD8	3	8	11	648.26
#435	HOXC10	3	9	12	879.796
#436	MSX2	3	8	11	838.187
#437	CUX2	3	5	8	203.497
#438	BLZF1	3	12	15	492.652
#439	ZNF85	3	10	13	1296.911
#440	RARB	3	13	16	1209.116
#441	BHLHE41	3	12	15	442.453
#442	SUPT4H1	3	9	12	703.043
#443	FOXJ3	3	7	10	294.554
#444	TGIF1	3	8	11	1008.524
#445	POU4F3	3	6	9	931.786
#446	RELA	3	9	12	657.4
#447	AATF	3	9	12	673.138
#448	HES1	3	13	16	1028.934
#449	HEY2	3	6	9	2856.827
#450	EPAS1	3	9	12	209.234
#451	GLI3	3	11	14	643.619
#452	HNF1A	3	8	11	648.779
#453	IRF7	3	9	12	1546.675
#454	HOXD4	3	5	8	541.098
#455	CNBP	3	9	12	987.433
#456	ASCL1	3	5	8	1509.612
#457	CSRNP2	3	6	9	652.667
#458	HOXB13	3	10	13	1718.168
#459	ZNF394	3	6	9	417.475
#460	FOXD3	2	13	15	1171.148
#461	PRDM2	2	7	9	161.623
#462	SRY	2	9	11	562.385
#463	TP53	2	14	16	464.105
#464	TSC22D2	2	8	10	366.595
#465	POU1F1	2	7	9	306.6
#466	PRRX1	2	10	12	362.462
#467	SMAD5	2	8	10	476.299
#468	TAF13	2	4	6	186.169
#469	MSC	2	9	11	323.526
#470	FOXG1	2	7	9	283.407
#471	SUPT6H	2	4	6	265.502
#472	SP140	2	10	12	348.08
#473	ZNF167	2	13	15	1099.749
#474	LZTR1	2	6	8	199.187
#475	ZSCAN16	2	11	13	457.725
#476	RCAN1	2	14	16	815.611
#477	NFATC4	2	8	10	417.949
#478	CNOT7	2	9	11	536.434
#479	ZNF277	2	7	9	887.682
#480	EGR4	2	7	9	146.383
#481	ATF2	2	11	13	315.371
#482	SALL1	2	9	11	1214.42
#483	PPARA	2	8	10	1168.687
#484	PLAG1	2	8	10	488.685
#485	HOXA9	1	9	10	76.629
#486	NFIL3	1	12	13	443.33
#487	ZNF135	1	8	9	219.466
#488	FOXD1	1	10	11	205.75
#489	ZNF155	1	8	9	179.438
#490	RBCK1	1	6	7	319.051
#491	NFYA	1	10	11	645.629
#492	CSDA	1	13	14	216.408
#493	ASCL2	1	14	15	317.87
#494	HMGB1	1	10	11	214.133
#495	FOXN2	1	7	8	367.78
#496	NR4A1	1	14	15	590.025
#497	NR5A2	0	6	6	0
#498	CREB5	0	11	11	0
#499	MYC	0	14	14	0
#500	ZNF80	0	6	6	0