Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MEF2C	52	4	56	632.47
#2	MAF	52	4	56	702.744
#3	CEBPD	50	3	53	60.701
#4	MTA1	50	2	52	170.631
#5	ZFP36L1	47	1	48	28.713
#6	ADNP	43	3	46	1699.934
#7	NFYA	42	10	52	2570.341
#8	ELK3	41	6	47	1564.88
#9	SOX12	41	8	49	4218.202
#10	FLI1	39	0	39	0
#11	HDAC2	38	1	39	1160.663
#12	CREM	36	14	50	2526.103
#13	RCAN1	36	9	45	2128.67
#14	CREB3L4	36	9	45	2768.976
#15	ZSCAN16	35	6	41	292.397
#16	MYCN	35	15	50	2954.441
#17	ZNF133	35	4	39	5374.002
#18	HOXB7	34	3	37	33.612
#19	NR2F2	34	6	40	2469.887
#20	ZNF3	33	5	38	157.785
#21	STAT6	33	12	45	1923.12
#22	TCF3	33	8	41	175.415
#23	BHLHE40	33	7	40	1596.196
#24	ZNF193	32	5	37	570.104
#25	CREB3L2	32	7	39	2006.732
#26	ELF1	32	9	41	600.386
#27	SOX4	32	11	43	829.112
#28	TRIM28	32	5	37	306.034
#29	UHRF1	31	2	33	198.706
#30	IRF9	31	11	42	1863.57
#31	MLL	31	1	32	48.92
#32	PHOX2B	30	14	44	6256.914
#33	NFIA	30	10	40	337.073
#34	YY1	30	3	33	469.923
#35	MAFK	30	12	42	4861.931
#36	GATA3	30	9	39	3482.53
#37	SIX5	28	9	37	2164.51
#38	NFE2L2	28	5	33	865.917
#39	SPEN	27	3	30	95.809
#40	HCLS1	27	5	32	40.088
#41	FUBP1	27	9	36	1291.407
#42	TRIM22	26	7	33	105.885
#43	ZFPM2	26	12	38	4081.613
#44	HOXC4	26	14	40	6597.488
#45	CREBBP	26	10	36	1164.196
#46	ZSCAN2	26	11	37	2139.876
#47	HSF2	26	5	31	198.415
#48	SP4	26	10	36	548.514
#49	YEATS4	26	10	36	17949.874
#50	NR3C1	25	14	39	10123.123
#51	BCL6	25	11	36	2574.167
#52	MLLT10	25	4	29	413.441
#53	FOXM1	24	2	26	58.801
#54	TGIF1	24	14	38	1805.817
#55	ZNF140	24	10	34	1650.859
#56	TAF5	24	9	33	421.105
#57	AHR	24	10	34	314.828
#58	GATAD2B	24	10	34	726.205
#59	ZNF367	24	5	29	564.449
#60	ZBTB38	24	8	32	3161.731
#61	TAF4	24	10	34	917.674
#62	TBP	23	14	37	1380.337
#63	ETV4	23	9	32	2653.368
#64	FOXK2	23	14	37	861.279
#65	KLF9	23	12	35	4360.177
#66	ZNF24	23	15	38	1358.459
#67	TCF4	23	10	33	910.695
#68	PLAGL2	23	13	36	991.263
#69	NFE2L1	22	10	32	797.945
#70	RUNX2	22	10	32	1221.368
#71	GATA2	22	17	39	699.637
#72	ZKSCAN2	22	14	36	1250.743
#73	PPARD	22	12	34	3912.151
#74	MYT1	22	11	33	3803.92
#75	HMGB2	22	5	27	745.532
#76	TEAD2	22	11	33	2133.217
#77	NFYB	21	7	28	1801.672
#78	PRDM2	21	13	34	1269.373
#79	RCOR2	21	10	31	752.266
#80	HMG20B	21	19	40	3000.801
#81	BCL3	21	13	34	608.465
#82	ZNF167	21	6	27	760.435
#83	IRF8	21	6	27	175.211
#84	ISL1	21	13	34	1490.921
#85	ZC3H8	21	11	32	1535.126
#86	ZNF639	20	11	31	560.01
#87	AEBP1	20	15	35	3692.421
#88	CREBZF	20	9	29	1062.934
#89	VAV1	20	7	27	1405.167
#90	NFIC	20	16	36	1947.184
#91	ETV6	20	9	29	1084.79
#92	MYBL2	20	4	24	265.408
#93	CNOT7	20	10	30	392.7
#94	PCGF2	20	10	30	811.21
#95	ZNF148	20	7	27	2592.135
#96	GLI3	20	9	29	2653.78
#97	FOXO3	19	9	28	700.511
#98	CREB1	19	5	24	1254.691
#99	PKNOX1	19	14	33	5444.029
#100	ETS1	19	12	31	456.932
#101	ONECUT2	19	14	33	1143.771
#102	KLF11	19	12	31	1818.216
#103	EGR2	18	9	27	3141.532
#104	ZNF92	18	10	28	1402.918
#105	MTA3	18	14	32	4807.598
#106	HNRNPAB	18	4	22	3645.041
#107	EPAS1	18	13	31	1705.873
#108	ELF4	18	15	33	3999.074
#109	TFAP2B	18	17	35	2334.669
#110	FOSL2	18	14	32	2157.444
#111	ZHX2	18	8	26	1073.06
#112	ZEB1	18	4	22	2592.638
#113	JUNB	18	3	21	22.622
#114	HHEX	18	7	25	5016.269
#115	KLF12	18	13	31	1658.205
#116	ZNF33A	18	5	23	446.51
#117	POU2F1	18	11	29	2001.328
#118	HEY1	18	16	34	2525.377
#119	MZF1	18	10	28	767.374
#120	TULP4	18	7	25	1111.365
#121	GATAD2A	18	10	28	2426.734
#122	ATF1	17	9	26	1111.806
#123	PLSCR1	17	10	27	190.34
#124	TCF12	17	11	28	1010.907
#125	HOXD4	17	8	25	1076.021
#126	ZNF498	17	13	30	957.262
#127	NR4A2	17	7	24	401.077
#128	GAS7	17	11	28	2128.564
#129	LMO4	17	16	33	3664.924
#130	KLF4	17	8	25	370.255
#131	NR3C2	17	7	24	626.811
#132	E2F3	17	10	27	344.213
#133	TEF	17	15	32	1909.387
#134	FOXO1	16	11	27	786.307
#135	ZNF274	16	12	28	596.94
#136	ETV1	16	20	36	4374.257
#137	ZXDC	16	9	25	329.368
#138	KDM5B	16	14	30	1321.055
#139	GCFC1	16	7	23	278.537
#140	LEF1	16	13	29	1175.977
#141	RORA	16	17	33	2376.958
#142	EGR1	16	13	29	1309.153
#143	MYT1L	16	14	30	1361.41
#144	ZNF207	16	12	28	592.052
#145	PRRX1	16	8	24	61.182
#146	HIC1	16	13	29	1487.791
#147	LCOR	16	15	31	1165.913
#148	GATAD1	15	12	27	1500.99
#149	CSDA	15	22	37	3997.038
#150	PTTG1	15	8	23	630.063
#151	NFAT5	15	6	21	495.719
#152	TBX2	15	19	34	2449.128
#153	FOXD3	15	4	19	191.346
#154	NFATC1	15	17	32	1572.193
#155	E2F8	15	8	23	1786.744
#156	NOTCH1	15	15	30	1331.781
#157	IKZF1	15	6	21	653.976
#158	MAFB	15	14	29	1896.197
#159	TCF7L1	15	12	27	700.788
#160	STAT3	15	14	29	629.875
#161	GABPB1	15	11	26	1190.163
#162	BTG2	15	13	28	532.09
#163	VAX2	15	10	25	861.291
#164	ZRANB2	15	5	20	96.112
#165	ECSIT	14	11	25	579.042
#166	CSRNP1	14	9	23	617.047
#167	NFATC3	14	10	24	1064.35
#168	ZNF93	14	11	25	1429.506
#169	SMAD4	14	6	20	1620.536
#170	CEBPB	14	14	28	423.934
#171	TP53	14	17	31	3779.726
#172	NR4A3	14	12	26	1495.919
#173	PBX1	14	14	28	2849.756
#174	FOS	14	6	20	103.76
#175	E2F1	14	9	23	1422.014
#176	ENO1	14	11	25	470.657
#177	SOX13	14	9	23	2020.499
#178	MGA	14	10	24	409.882
#179	CBFA2T2	14	13	27	1255.023
#180	ZSCAN21	14	11	25	871.879
#181	TFEB	14	13	27	9445.462
#182	MAFF	13	14	27	1585.784
#183	ZEB2	13	12	25	362.664
#184	PHOX2A	13	9	22	460.892
#185	EBF1	13	12	25	1538.061
#186	ETV5	13	18	31	1119.705
#187	THRA	13	10	23	833.432
#188	C1orf85	13	16	29	1776.861
#189	KLF7	13	10	23	1057.529
#190	NFATC2	13	18	31	2497.527
#191	ZFP36L2	13	14	27	4948.668
#192	ZFP37	13	8	21	278.745
#193	TRERF1	13	8	21	212.622
#194	CBFB	13	9	22	824.134
#195	ATF2	13	8	21	248.125
#196	FOXN3	13	15	28	1440.276
#197	MYNN	13	10	23	343.278
#198	JDP2	13	8	21	423.383
#199	ZNF71	13	12	25	1977.651
#200	ZNF496	13	16	29	4265.405
#201	GTF2I	13	1	14	68.679
#202	RBPJ	13	11	24	411.194
#203	CNOT8	13	14	27	1337.28
#204	CNBP	13	17	30	2717.076
#205	IRF1	12	11	23	1958.526
#206	POU4F1	12	5	17	1035.362
#207	NR1H3	12	14	26	855.257
#208	TAF10	12	14	26	743.333
#209	SMAD2	12	9	21	277.59
#210	SOX2	12	5	17	189.573
#211	CREBL2	12	13	25	1384.868
#212	TFAM	12	10	22	339.609
#213	HOXD3	12	17	29	1845.65
#214	KLF6	12	12	24	430.282
#215	MAX	12	10	22	1159.459
#216	TSHZ2	12	18	30	1612.076
#217	POU2F2	12	9	21	237.307
#218	HMGB1	12	10	22	1290.197
#219	ZFHX2	12	14	26	863.919
#220	E2F2	11	9	20	3008.194
#221	CSRNP3	11	10	21	1261.216
#222	DDIT3	11	16	27	2296.773
#223	KLF3	11	23	34	5266.905
#224	C5orf41	11	19	30	2503.123
#225	ZSCAN12	11	15	26	701.623
#226	ARNT2	11	14	25	2110.608
#227	ZNF500	11	12	23	493.761
#228	TFE3	11	13	24	360.614
#229	SOX10	11	2	13	16.884
#230	FOXP2	11	8	19	980.871
#231	TARDBP	11	12	23	456.907
#232	ETS2	11	14	25	2057.574
#233	SRF	11	16	27	1654.454
#234	ARID4A	11	21	32	1758.856
#235	MSRB2	11	14	25	350.281
#236	HMX1	11	13	24	939.748
#237	EGR3	11	9	20	330.422
#238	SALL2	11	10	21	1266.447
#239	RUNX1	11	15	26	1455.703
#240	STAT5B	11	8	19	4678.352
#241	HOXA5	11	12	23	6412.856
#242	HMGA1	11	11	22	1768.445
#243	SATB1	11	17	28	1544.549
#244	RCOR1	11	12	23	766.739
#245	SREBF1	10	13	23	1747.043
#246	ZNF397	10	14	24	2969.135
#247	TCF19	10	14	24	2323.8
#248	RARB	10	14	24	4491.984
#249	SOX17	10	12	22	856.273
#250	FOXK1	10	15	25	1066.516
#251	IRF7	10	13	23	550.118
#252	ZNF117	10	22	32	1645.631
#253	FOXS1	10	14	24	2280.389
#254	ZNF131	10	15	25	2074.06
#255	SLC2A4RG	10	12	22	1572.612
#256	ZIC2	10	6	16	1083.334
#257	NFKB1	10	13	23	1010.637
#258	MAFG	10	11	21	654.165
#259	KLF2	10	12	22	544.124
#260	C11orf9	10	16	26	707.996
#261	PRDM1	10	21	31	1782.421
#262	NFX1	10	11	21	1308.709
#263	SOX15	10	17	27	2277.431
#264	MEIS2	10	17	27	2734.028
#265	SOX11	10	22	32	2491.38
#266	MYC	10	20	30	953.082
#267	NFXL1	10	20	30	3716.492
#268	TFEC	10	13	23	1168.98
#269	E2F5	10	14	24	811.025
#270	ZKSCAN5	10	17	27	1596.244
#271	ZNF45	10	14	24	1206.202
#272	ZHX1	10	10	20	1060.528
#273	SP1	10	6	16	258.475
#274	KDM5A	10	12	22	1522.834
#275	EOMES	9	9	18	415.59
#276	SCAND3	9	16	25	2954.716
#277	TFAP2A	9	7	16	289.034
#278	ZKSCAN1	9	12	21	976.889
#279	SOX8	9	5	14	449.115
#280	BCL11B	9	21	30	609.433
#281	RUNX1T1	9	17	26	3035.71
#282	ERG	9	8	17	190.626
#283	HOXD8	9	13	22	682.025
#284	ZNF217	9	17	26	954.133
#285	ZNF281	9	18	27	2278.028
#286	ZNF187	9	9	18	275.419
#287	MITF	9	20	29	3340.302
#288	ZFHX3	9	15	24	1307.365
#289	CITED1	9	18	27	1396.342
#290	FOSB	9	7	16	239.007
#291	CUX1	9	12	21	787.546
#292	E2F7	9	13	22	3910.622
#293	ESRRG	9	21	30	2877.105
#294	PBX2	9	20	29	3431.745
#295	RXRA	9	12	21	2727.638
#296	CBL	9	12	21	1862.173
#297	SCML1	9	19	28	2078.921
#298	HES6	9	16	25	886.075
#299	TCFL5	9	10	19	587.192
#300	ATF5	9	24	33	2168.617
#301	KLF15	9	10	19	902.504
#302	ADNP2	9	15	24	2131.762
#303	HOPX	9	19	28	823.921
#304	LASS6	9	16	25	2095.221
#305	HES1	9	15	24	1286.333
#306	HOXA2	9	10	19	1593.092
#307	RXRG	9	7	16	2821.281
#308	SP3	9	12	21	769.475
#309	SP140	9	5	14	1519.438
#310	AFF4	9	6	15	750.915
#311	PPARA	9	12	21	1244.732
#312	HMX2	9	6	15	1247.123
#313	PURB	8	18	26	3586.612
#314	ZNF138	8	12	20	1842.564
#315	MEIS1	8	27	35	2016.1
#316	TCF25	8	13	21	1302.589
#317	HOXD9	8	14	22	2101.113
#318	SIX2	8	8	16	336.565
#319	AHCTF1	8	11	19	1277.813
#320	ZNF33B	8	14	22	955.044
#321	TFAP2D	8	4	12	412.999
#322	HAND1	8	19	27	2127.059
#323	BACH1	8	18	26	3474.616
#324	SOLH	8	11	19	629.249
#325	SLC30A9	8	11	19	11214.741
#326	ZNF83	8	17	25	2450.667
#327	TFDP1	8	18	26	1771.089
#328	TSC22D3	8	13	21	626.962
#329	SMAD9	8	19	27	2415.411
#330	SNAI2	8	14	22	430.212
#331	BATF3	8	11	19	2198.656
#332	NR4A1	8	9	17	341.144
#333	IKZF4	8	13	21	441.96
#334	NOLC1	8	11	19	1259.927
#335	XBP1	8	9	17	290.732
#336	RORC	8	10	18	2774.777
#337	RELA	8	14	22	3592.07
#338	HEYL	8	20	28	1345.001
#339	ARNTL2	8	15	23	782.365
#340	TLX2	8	18	26	2685.005
#341	FOXR1	7	7	14	4146.671
#342	HOXD13	7	7	14	3667.743
#343	NCOR1	7	11	18	1225.495
#344	TBX1	7	15	22	4546.015
#345	TEAD1	7	15	22	532.677
#346	SMAD5	7	17	24	1000.93
#347	C2orf3	7	17	24	752.907
#348	BHLHE41	7	23	30	706.16
#349	RFX5	7	16	23	383.849
#350	SNAPC4	7	13	20	499.983
#351	ZNF85	7	14	21	1133.004
#352	ARNT	7	15	22	1416.012
#353	WNT5A	7	10	17	2365.308
#354	ZNF70	7	14	21	727.986
#355	TSHZ3	7	17	24	1468.234
#356	ZSCAN18	7	16	23	511.756
#357	TWIST1	7	22	29	3077.305
#358	FOXC2	7	12	19	349.271
#359	TAF1B	7	15	22	1881.423
#360	SPIB	7	11	18	427.018
#361	GTF2H4	7	15	22	1593.247
#362	E2F6	7	13	20	913.315
#363	VDR	7	13	20	1245.768
#364	TCF7L2	6	12	18	354.169
#365	TEAD4	6	21	27	792.709
#366	TGIF2	6	20	26	1844.016
#367	HOXB3	6	16	22	1299.963
#368	NFIB	6	21	27	2923.186
#369	RUNX3	6	10	16	668.975
#370	HOXD11	6	8	14	1765.691
#371	CSRNP2	6	20	26	705.221
#372	GTF2H3	6	13	19	1467.856
#373	ZNF232	6	15	21	692.909
#374	FOXC1	6	14	20	979.939
#375	SOX9	6	18	24	528.29
#376	NR2F1	6	22	28	1795.275
#377	SIN3A	6	15	21	1357.662
#378	GTF2H2	6	17	23	2353.149
#379	MTF1	6	15	21	1095.466
#380	PKNOX2	6	10	16	134.174
#381	HOXC9	6	23	29	4998.291
#382	FOSL1	6	10	16	1609.369
#383	NFYC	6	14	20	620.101
#384	PITX2	6	7	13	3271.572
#385	STAT5A	6	16	22	884.825
#386	DLX6	6	10	16	520.772
#387	STAT1	6	12	18	288.867
#388	ST18	6	8	14	806.189
#389	MSX1	5	12	17	204.799
#390	ARNTL	5	16	21	786.418
#391	MYCL1	5	17	22	1490.322
#392	ZXDA	5	20	25	984.29
#393	ZNF202	5	10	15	79.526
#394	SUPT4H1	5	13	18	166.765
#395	NR1D2	5	13	18	542.086
#396	TCF21	5	7	12	75.193
#397	MXD1	5	14	19	2647.232
#398	TSC22D1	5	18	23	213.707
#399	SCAND1	5	12	17	234.178
#400	PPARG	5	12	17	2361.04
#401	SMAD1	5	18	23	2279.492
#402	IRX5	5	10	15	2171.145
#403	NFIL3	5	16	21	1165.252
#404	YBX1	5	13	18	605.346
#405	FOXR2	5	7	12	3646.481
#406	CREB5	5	16	21	610.447
#407	ZNF287	5	12	17	2311.143
#408	CUX2	5	24	29	493.78
#409	ZNF91	4	16	20	828.971
#410	VTN	4	13	17	1738.148
#411	FOXP1	4	19	23	935.084
#412	HIRA	4	10	14	491.468
#413	MEIS3	4	12	16	475.056
#414	MEOX2	4	13	17	519.334
#415	FOXO6	4	17	21	275.89
#416	HLF	4	17	21	691.343
#417	TCF7	4	18	22	1397.636
#418	PEG3	4	20	24	1149.85
#419	PCGF6	4	13	17	386.416
#420	CDKN2A	4	20	24	1004.611
#421	DLX1	4	7	11	281.817
#422	CEBPA	4	11	15	354.399
#423	SOX7	4	18	22	400.304
#424	REL	4	14	18	444.109
#425	CREB3L1	4	16	20	794.951
#426	JUND	4	18	22	753.279
#427	NFE2L3	4	12	16	1166.751
#428	ZNF238	4	16	20	183.396
#429	SMAD3	4	16	20	436.504
#430	LHX8	4	7	11	4108.173
#431	LZTS1	4	21	25	973.794
#432	HR	4	18	22	1268.226
#433	ASCL1	3	26	29	225.331
#434	ATF3	3	21	24	2056.986
#435	PURA	3	13	16	125.148
#436	MECOM	3	19	22	145.418
#437	HOXD10	3	17	20	1264.791
#438	GLIS2	3	18	21	269.038
#439	PROX1	3	12	15	219.041
#440	CITED2	3	15	18	1349.942
#441	ZFHX4	3	22	25	781.887
#442	HINFP	3	17	20	220.628
#443	IRF6	3	12	15	2862.9
#444	PBX3	3	17	20	564.853
#445	ARX	3	26	29	2801.86
#446	NR0B1	3	9	12	561.215
#447	ZNF277	3	15	18	272.483
#448	SIX3	3	24	27	3224.688
#449	KLF10	3	18	21	1319.555
#450	FOXI1	3	6	9	27.725
#451	BACH2	3	17	20	221.535
#452	NFIX	3	22	25	491.842
#453	SIX6	3	8	11	1630.995
#454	KLF16	3	15	18	1154.987
#455	HMBOX1	3	20	23	1384.974
#456	TSHZ1	3	12	15	722.934
#457	TFDP2	3	19	22	187.154
#458	IRF5	2	17	19	563.175
#459	HOXB2	2	17	19	159.041
#460	PAX8	2	13	15	67.913
#461	RARA	2	10	12	1430.944
#462	TRPS1	2	20	22	90.608
#463	PITX1	2	7	9	178.775
#464	HOXC10	2	27	29	355.021
#465	GATA6	2	25	27	274.103
#466	HEY2	2	16	18	1766.007
#467	ALX1	2	14	16	255.315
#468	JUN	2	14	16	952.655
#469	L3MBTL4	2	19	21	86.429
#470	FOXN2	2	17	19	57.723
#471	TAF4B	2	19	21	753.072
#472	GLIS3	2	13	15	649.836
#473	TBX3	2	26	28	1707.292
#474	SOX6	2	24	26	93.192
#475	SMAD6	2	14	16	201.849
#476	ZFP90	2	18	20	188.896
#477	POU6F1	2	19	21	1334.425
#478	ZIC1	2	5	7	57.446
#479	ZNF394	1	18	19	281.917
#480	TRIM25	1	17	18	26.954
#481	MEOX1	1	11	12	58.269
#482	MEIS3P1	1	18	19	113.402
#483	POU3F2	1	14	15	49.085
#484	ZNF268	1	14	15	43.703
#485	RORB	1	20	21	62.761
#486	FOXD1	1	15	16	522.589
#487	DLX2	1	6	7	34.102
#488	FOXP4	1	15	16	39.813
#489	TRIM29	1	14	15	106.259
#490	PHTF1	1	21	22	875.743
#491	HOXD1	1	17	18	98.319
#492	POU4F2	1	26	27	1068.088
#493	KLF5	1	10	11	198.318
#494	CTBP1	0	15	15	0
#495	CTNNB1	0	15	15	0
#496	STAT4	0	10	10	0
#497	KCNH8	0	20	20	0
#498	EN1	0	8	8	0
#499	IRX3	0	17	17	0
#500	FEV	0	27	27	0