Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HOXA5	47	8	55	992.795
#2	GATA6	46	5	51	6021.61
#3	CREBL2	40	9	49	1693.871
#4	FOXM1	35	1	36	1197.862
#5	MSX1	34	8	42	1096.415
#6	FOSL2	33	6	39	466.218
#7	PTTG1	33	1	34	18.458
#8	CREM	32	4	36	490.633
#9	TCF3	31	11	42	3163.324
#10	GTF2I	31	2	33	1121.222
#11	STAT5B	30	5	35	2322.832
#12	MTA3	30	5	35	1162.071
#13	HOXD10	30	11	41	6727.56
#14	HCLS1	28	5	33	1268.575
#15	BATF3	28	6	34	2499.319
#16	IKZF1	27	0	27	0
#17	YBX1	26	4	30	861.485
#18	ETS2	26	8	34	1368.528
#19	HMGB2	26	3	29	81.363
#20	CBFB	26	7	33	1295.956
#21	MITF	25	10	35	1715.286
#22	ZNF193	25	6	31	3707.133
#23	MEIS1	25	8	33	1366.232
#24	ZFP90	25	9	34	2564.94
#25	ZNF496	25	9	34	2299.765
#26	PPARA	25	10	35	3875.201
#27	IRF8	24	5	29	941.28
#28	KDM5B	24	11	35	2246.46
#29	ZIC2	24	9	33	2031.376
#30	TSC22D4	24	5	29	1969.719
#31	NFYA	24	7	31	2187.209
#32	TFCP2	24	9	33	1980.113
#33	NR2F1	23	7	30	883.992
#34	MEIS2	23	10	33	3543.903
#35	ZEB2	23	11	34	2150.298
#36	TRPS1	23	16	39	9559.202
#37	NR4A2	23	3	26	1471.731
#38	ZNF367	23	3	26	473.528
#39	STAT5A	23	4	27	931.337
#40	CSRNP1	22	6	28	785.487
#41	NR3C1	22	9	31	2283.72
#42	FOXN3	22	10	32	1420.878
#43	SP1	22	1	23	29.288
#44	ETV5	22	6	28	1609.307
#45	CREB3L1	22	6	28	4015.938
#46	TFE3	21	7	28	2225.13
#47	CREB1	21	7	28	480.302
#48	NFYC	21	5	26	451.958
#49	NR1H3	21	12	33	2172.357
#50	LCOR	21	9	30	871.64
#51	DLX1	20	9	29	1490.983
#52	ZHX2	20	5	25	523.647
#53	ZSCAN18	19	9	28	5027.934
#54	EPAS1	19	5	24	1573.917
#55	SATB1	19	14	33	3441.144
#56	NPAS2	19	13	32	2809.324
#57	GABPA	19	9	28	2056.72
#58	RXRB	19	4	23	421.48
#59	ZFHX4	19	8	27	3765.471
#60	ZNF207	19	8	27	1039.682
#61	TRIM22	19	8	27	1461.837
#62	UHRF1	19	6	25	209.614
#63	E2F1	18	4	22	418.216
#64	ZNF140	18	6	24	492.076
#65	SOX4	18	11	29	3091.829
#66	MLLT10	18	11	29	1508.216
#67	MAFF	18	7	25	486.327
#68	EBF1	18	10	28	1445.625
#69	TFEC	18	4	22	824.243
#70	BRD8	18	13	31	3840.756
#71	ATF1	18	6	24	610.429
#72	HOXC13	18	9	27	1450.684
#73	TWIST1	17	7	24	851.363
#74	ZNF263	17	3	20	282.742
#75	NR4A3	17	13	30	1776.649
#76	HMGA2	17	10	27	940.473
#77	GATA3	17	11	28	3609.393
#78	ZFPM2	17	10	27	1927.705
#79	NFATC4	17	10	27	3047.468
#80	SCML1	17	9	26	1950.206
#81	HLF	17	19	36	5501.268
#82	HOXD9	17	7	24	809.449
#83	ZC3H8	17	14	31	2419.507
#84	TCF19	17	6	23	464.815
#85	TAF12	16	6	22	1573.577
#86	GTF2H2	16	9	25	1363.141
#87	LEF1	16	7	23	1386.384
#88	CUX1	16	8	24	1198.67
#89	RB1	16	8	24	2943.221
#90	TCF7L2	16	3	19	1067.346
#91	SUPT6H	16	9	25	908.379
#92	FOXO4	16	10	26	2185.267
#93	HOXB13	16	11	27	1981.332
#94	TCFL5	16	8	24	1143.611
#95	HDAC1	16	9	25	987.15
#96	FOXK2	16	7	23	1034.478
#97	MAF	16	13	29	4883.49
#98	MTF1	16	5	21	405.807
#99	SREBF1	16	9	25	1391.042
#100	HOXB6	16	9	25	1502.427
#101	TAF10	15	12	27	2098.527
#102	RARA	15	10	25	1203.781
#103	RUNX3	15	5	20	2051.697
#104	SOX12	15	11	26	1584.329
#105	NFXL1	15	8	23	832.576
#106	HMX2	15	11	26	2299.558
#107	RORA	15	13	28	5020.791
#108	SNAI2	15	11	26	2211.103
#109	RELA	14	7	21	557.878
#110	TSC22D3	14	12	26	1458.597
#111	NOLC1	14	6	20	1024.155
#112	PROX1	14	10	24	1701.959
#113	C5orf41	14	12	26	2131.387
#114	ZKSCAN4	14	6	20	593.304
#115	NR3C2	14	15	29	1555.227
#116	TCF12	14	9	23	2447.597
#117	HOXD11	14	9	23	1160.043
#118	AFF4	14	10	24	3015.931
#119	SCAND1	14	11	25	2066.755
#120	IRF6	14	8	22	3204.52
#121	NFIL3	14	3	17	30.763
#122	ZNF133	14	10	24	1476.508
#123	RERE	14	6	20	773.912
#124	FLI1	14	8	22	463.347
#125	PBX4	14	10	24	2582.778
#126	NR0B1	14	4	18	373.329
#127	EGR3	13	5	18	707.825
#128	JUNB	13	3	16	49.385
#129	CNOT8	13	7	20	1895.349
#130	MMP14	13	11	24	1251.509
#131	EN1	13	10	23	1512.534
#132	GCFC1	13	12	25	1379.107
#133	NR2F6	13	6	19	1235.795
#134	MYC	13	13	26	2390.237
#135	GATAD1	13	9	22	1124.026
#136	ETV1	13	11	24	2118.965
#137	RUNX2	13	8	21	756.659
#138	E2F2	13	7	20	380.563
#139	IRF7	13	6	19	3757.724
#140	XBP1	13	9	22	2413.249
#141	ZSCAN16	13	9	22	2002.358
#142	RXRA	13	14	27	1851.787
#143	TSC22D2	13	10	23	2320.833
#144	HOXC9	13	7	20	439.058
#145	CREBZF	13	11	24	2895.184
#146	PBX3	12	15	27	2036.405
#147	SMAD5	12	8	20	681.278
#148	ZNF277	12	5	17	372.807
#149	IRX3	12	11	23	2166.768
#150	THRB	12	9	21	663.826
#151	HOXA2	12	7	19	256.95
#152	ELF4	12	10	22	201.045
#153	EGR1	12	11	23	1643.702
#154	ZNF83	12	10	22	1200.098
#155	TGIF1	12	16	28	2734.904
#156	HOXA13	12	16	28	1391.812
#157	STAT1	12	10	22	3145.096
#158	CNOT7	12	7	19	550.655
#159	SIX1	12	10	22	1271.986
#160	NFIX	12	17	29	4844.569
#161	TCF4	12	11	23	3269.308
#162	TBX3	12	9	21	1218.504
#163	CBL	12	10	22	1680.412
#164	ZNF92	11	7	18	572.879
#165	MEIS3P1	11	10	21	697.265
#166	CDKN2A	11	15	26	5388.831
#167	PBX1	11	7	18	920.079
#168	CSDA	11	12	23	2214.139
#169	FOXP1	11	12	23	1494.886
#170	ENO1	11	12	23	995.161
#171	E2F3	11	7	18	1364.402
#172	AHCTF1	11	13	24	3429.05
#173	RFX5	11	10	21	1976.994
#174	ZNF189	11	9	20	2424.317
#175	GATAD2B	11	10	21	1367.89
#176	HOXB3	11	5	16	452.952
#177	HSF4	11	9	20	451.237
#178	PHTF1	11	8	19	810.571
#179	ELK3	11	7	18	1069.737
#180	SMAD2	11	5	16	268.934
#181	SALL2	11	13	24	3832.995
#182	FOXD1	11	13	24	517.399
#183	WT1	10	8	18	918.278
#184	E2F7	10	5	15	2675.879
#185	FOSB	10	11	21	570.842
#186	NKX3-1	10	8	18	777.025
#187	MZF1	10	16	26	1847.526
#188	ZFP37	10	10	20	874.243
#189	ZFP36L2	10	13	23	576.655
#190	FOXO3	10	13	23	4344.73
#191	ONECUT2	10	10	20	1337.891
#192	CSRNP3	10	16	26	3836.431
#193	LZTS1	10	11	21	1844.121
#194	EGR2	10	7	17	2358.63
#195	HOXC10	10	10	20	1407.736
#196	SIM2	10	8	18	752.827
#197	GATA1	10	10	20	1283.246
#198	BTG2	10	8	18	717.84
#199	CBFA2T2	10	11	21	1081.573
#200	NFIB	10	6	16	609.6
#201	GTF2H3	10	5	15	660.804
#202	KLF2	10	12	22	653.586
#203	FUBP1	10	11	21	721.09
#204	ISL1	10	11	21	1494.949
#205	GLIS2	10	11	21	1304.04
#206	KLF9	9	14	23	3468.728
#207	NR4A1	9	6	15	402.38
#208	HOXA9	9	10	19	2324.609
#209	ATF3	9	8	17	250.803
#210	NR1H4	9	12	21	1769.467
#211	HOXA10	9	9	18	1404.228
#212	CEBPD	9	14	23	1618.635
#213	LHX2	9	10	19	1333.237
#214	STAT6	9	8	17	1230.499
#215	IRF1	9	14	23	1600.86
#216	MECOM	9	14	23	1691.653
#217	TBX2	9	16	25	3845.994
#218	ZNF215	9	10	19	2334.481
#219	GAS7	9	9	18	1437.333
#220	KLF15	9	10	19	1238.891
#221	ZNF85	9	11	20	2892.263
#222	TFEB	9	11	20	807.595
#223	RARB	9	14	23	3435.406
#224	SREBF2	9	12	21	976.665
#225	ZNF93	9	11	20	1691.142
#226	HOXC4	9	10	19	1319.128
#227	MSX2	9	10	19	1616.891
#228	TSHZ3	9	12	21	1678.616
#229	L3MBTL4	9	12	21	184.595
#230	ZFHX3	9	11	20	1305.66
#231	SOX7	9	10	19	2015.269
#232	NFIA	9	9	18	2731.737
#233	ZNF24	9	9	18	704.44
#234	MAX	9	12	21	1080.772
#235	ZNF131	9	6	15	724.89
#236	HSF2	9	4	13	594.596
#237	HMGB1	9	6	15	632.792
#238	SMAD4	9	9	18	483.797
#239	CSRNP2	9	7	16	166.168
#240	PCGF2	9	11	20	1339.308
#241	ZNF148	9	11	20	799.495
#242	ATF7	9	9	18	929.853
#243	DLX6	8	11	19	816.973
#244	MBD1	8	11	19	784.46
#245	HEY2	8	9	17	406.324
#246	ZNF274	8	7	15	984.342
#247	LHX6	8	13	21	1340.555
#248	HMGA1	8	10	18	1002.993
#249	NR1D2	8	14	22	2038.933
#250	POU3F2	8	5	13	1158.446
#251	ZFPM1	8	13	21	1289.772
#252	TCF21	8	11	19	1076.583
#253	AEBP1	8	14	22	2047.555
#254	ZIC1	8	14	22	1515.945
#255	SLC2A4RG	8	9	17	955.253
#256	PRDM1	8	11	19	1368.426
#257	ZNF37A	8	9	17	1100.98
#258	HOXD13	8	9	17	788.12
#259	MESP1	8	16	24	1390.453
#260	SMAD9	8	9	17	1816.909
#261	TADA3	8	14	22	1689.039
#262	CTNNB1	8	11	19	875.603
#263	HOXD4	8	8	16	1365.959
#264	ZNF217	8	10	18	1902.394
#265	BATF2	8	8	16	597.523
#266	NR5A2	8	7	15	1487.303
#267	HOXB7	8	7	15	901.072
#268	MYT1	8	12	20	925.715
#269	TP53	8	11	19	1060.034
#270	SCAND3	7	11	18	1190.422
#271	MAFG	7	13	20	1039.702
#272	BHLHE41	7	12	19	2729.279
#273	CLOCK	7	9	16	2503.896
#274	ZNF91	7	11	18	1368.558
#275	CREB5	7	12	19	1534.1
#276	SPI1	7	7	14	1807.484
#277	GLI3	7	12	19	1251.481
#278	NR2F2	7	6	13	521.324
#279	VTN	7	11	18	1560.588
#280	ZNF397	7	12	19	718.872
#281	C11orf9	7	12	19	1258.007
#282	ETV6	7	9	16	1487.339
#283	REL	7	10	17	314.376
#284	SOX15	7	10	17	1471.805
#285	ZNF138	7	6	13	525.199
#286	ELF1	7	12	19	680.976
#287	TEAD2	7	14	21	1769.926
#288	FOS	7	7	14	325.177
#289	BATF	7	4	11	1401.722
#290	NKX3-2	7	12	19	562.714
#291	ETS1	7	9	16	1578.056
#292	YEATS4	7	10	17	928.63
#293	E2F8	7	7	14	101.596
#294	HES6	7	14	21	3912.974
#295	MEF2C	7	13	20	576.242
#296	RCAN1	7	10	17	1083.208
#297	SOX13	7	11	18	894.766
#298	ZKSCAN1	7	11	18	641.577
#299	JDP2	7	13	20	2117.986
#300	KLF6	7	10	17	943.006
#301	SIX2	7	8	15	1601.353
#302	HOXA7	7	10	17	1237.991
#303	TSC22D1	7	8	15	937.64
#304	MYBL2	7	8	15	1420.628
#305	TBX5	6	10	16	758.61
#306	KLF16	6	12	18	1603.746
#307	MNX1	6	9	15	1982.98
#308	FOXC1	6	9	15	501.651
#309	AHR	6	12	18	1010.55
#310	ZXDC	6	11	17	2096.702
#311	FOXA2	6	14	20	2255.782
#312	PEG3	6	9	15	1070.885
#313	RUNX1	6	13	19	1076.129
#314	RBCK1	6	12	18	783.769
#315	IRF5	6	9	15	349.765
#316	SMAD3	6	10	16	407.971
#317	ZNF394	6	11	17	1967.693
#318	SOX17	6	8	14	986.685
#319	WNT5A	6	14	20	875.1
#320	TFDP2	6	11	17	2400.178
#321	PAX8	6	10	16	627.813
#322	ARNTL	6	13	19	317.483
#323	KLF3	6	11	17	1528.721
#324	ZNF135	6	7	13	451.029
#325	BCL3	6	12	18	1331.719
#326	NFIC	6	11	17	1243.1
#327	ZFP36L1	6	15	21	2974.368
#328	THRA	6	10	16	714.131
#329	HIC1	6	12	18	631.036
#330	SLC30A9	6	12	18	1685.214
#331	NFATC1	6	11	17	534.394
#332	HOXB1	6	14	20	1171.677
#333	ESRRG	6	10	16	812.899
#334	KLF10	6	9	15	1238.802
#335	MEIS3	6	7	13	937.125
#336	TULP4	6	15	21	1947.438
#337	RORB	6	14	20	3117.168
#338	IKZF4	6	12	18	1899.762
#339	GABPB1	6	14	20	565.837
#340	DBP	6	9	15	636.263
#341	HOXA3	5	13	18	1678.215
#342	FOSL1	5	11	16	381.738
#343	FOXO1	5	14	19	781.263
#344	MKX	5	13	18	528.194
#345	TFAP2A	5	10	15	379.71
#346	POU3F1	5	11	16	684.002
#347	TEAD4	5	12	17	1315.506
#348	HOXD8	5	3	8	21.729
#349	MYCN	5	8	13	1633.664
#350	ETV4	5	12	17	437.896
#351	MAFB	5	13	18	3799.588
#352	NFATC2	5	11	16	588.71
#353	BARX1	5	10	15	613.736
#354	KLF12	5	7	12	222.676
#355	FBXW7	5	13	18	1615.281
#356	ZNF71	5	10	15	543.669
#357	MSC	5	15	20	1950.794
#358	ARNT	5	13	18	609.967
#359	DDIT3	5	12	17	587.105
#360	HAND1	5	11	16	1484.233
#361	BCL11B	5	12	17	711.534
#362	ZNF165	5	10	15	483.429
#363	ARNT2	5	16	21	1921.942
#364	MSRB2	5	16	21	563.818
#365	KLF11	5	10	15	855.245
#366	NFE2L2	5	9	14	1303.685
#367	MLXIPL	5	13	18	812.139
#368	FOXO6	5	13	18	1012.637
#369	NR2E1	5	10	15	1100.664
#370	UBN1	5	9	14	702.012
#371	HOXA11	5	11	16	968.297
#372	KLF4	5	10	15	180.819
#373	EOMES	5	7	12	479.175
#374	SIX5	5	12	17	571.755
#375	GLI2	4	17	21	891.845
#376	IRF9	4	7	11	491.319
#377	HOXA1	4	13	17	540.367
#378	JUND	4	14	18	496.218
#379	RORC	4	14	18	1729.14
#380	CITED2	4	9	13	223.532
#381	LASS6	4	10	14	565.237
#382	HOXB8	4	9	13	2007.107
#383	E2F5	4	10	14	2611.961
#384	ZNF500	4	7	11	283.283
#385	ZNF75D	4	17	21	1038.158
#386	HIF3A	4	10	14	1295.022
#387	TFDP1	4	12	16	822.75
#388	CREB3L2	4	11	15	926.419
#389	TCF15	4	12	16	402.489
#390	NFX1	4	7	11	393.173
#391	POU4F1	4	10	14	427.71
#392	HOXC11	4	6	10	294.04
#393	ZNF167	4	10	14	1043.979
#394	SOX1	4	5	9	164.417
#395	MAFK	4	19	23	1528.732
#396	STAT3	4	12	16	1076.429
#397	PGR	4	14	18	764.519
#398	NFAT5	4	14	18	819.133
#399	TWIST2	4	13	17	1553.599
#400	MLL	4	7	11	660.62
#401	EHF	4	13	17	703.619
#402	MYNN	4	4	8	111.936
#403	PURB	4	8	12	763.874
#404	ATF5	4	11	15	1341.042
#405	TAF5	4	8	12	75.14
#406	AR	4	12	16	1053.844
#407	TSHZ2	4	8	12	285.39
#408	GATA5	4	10	14	650.039
#409	GATA4	4	18	22	1048.244
#410	ESR1	4	12	16	713.473
#411	HSF1	4	12	16	992.442
#412	ZEB1	4	13	17	262.61
#413	PITX1	4	13	17	1145.369
#414	NKX2-1	3	4	7	107.692
#415	SIX4	3	16	19	1128.317
#416	CREB3	3	11	14	317.14
#417	HMBOX1	3	17	20	390.677
#418	SPEN	3	11	14	700.73
#419	MXD1	3	13	16	711.376
#420	KLF5	3	8	11	258.217
#421	PHOX2B	3	8	11	1100.269
#422	HOXD3	3	10	13	159.048
#423	MEOX2	3	8	11	285.033
#424	PPARG	3	9	12	1163.454
#425	PAX6	3	10	13	891.9
#426	SPDEF	3	13	16	513.311
#427	MEF2D	3	9	12	280.509
#428	TFCP2L1	3	9	12	308.939
#429	SOX6	3	11	14	774.932
#430	ARX	3	13	16	843.44
#431	RUNX1T1	3	18	21	639.646
#432	BACH2	3	8	11	302.835
#433	PLSCR1	3	11	14	785.317
#434	EVX1	3	10	13	356.122
#435	C1orf85	3	10	13	374.937
#436	VDR	3	14	17	346.443
#437	HOXB4	3	8	11	395.683
#438	ZNF219	3	10	13	470.094
#439	IRX2	3	8	11	209.746
#440	ZBTB38	3	14	17	667.483
#441	SOX2	3	8	11	940.684
#442	CITED1	3	10	13	395.711
#443	FOXP2	3	12	15	1707.253
#444	TFAP2C	3	11	14	1195.73
#445	TAL1	3	7	10	397.861
#446	MGA	3	7	10	485.783
#447	NR5A1	3	11	14	523.272
#448	ZNF117	3	14	17	280.188
#449	SRY	2	7	9	774.755
#450	SMAD6	2	12	14	317.873
#451	GTF2IRD1	2	15	17	274.443
#452	HAND2	2	9	11	215.292
#453	HOXB2	2	13	15	1239.233
#454	HOXB9	2	14	16	4960.637
#455	HEY1	2	16	18	435.485
#456	HOPX	2	19	21	970.899
#457	RARG	2	12	14	943.265
#458	IRX4	2	6	8	161.75
#459	JUN	2	14	16	459.184
#460	TEF	2	9	11	351.371
#461	HMX1	2	3	5	471.351
#462	NFYB	2	11	13	490.249
#463	FOXC2	2	16	18	368.746
#464	BHLHE40	2	16	18	793.154
#465	STRN3	2	11	13	877.618
#466	SOX8	2	14	16	252.466
#467	PLAG1	2	9	11	210.135
#468	GLIS3	2	11	13	410.399
#469	TCF25	2	11	13	481.281
#470	FOXG1	2	6	8	873.17
#471	PKNOX2	2	9	11	264.89
#472	PRRX1	2	18	20	454.438
#473	HEYL	2	13	15	755.911
#474	ZBTB17	2	10	12	194.377
#475	FOXL2	2	14	16	283.649
#476	ZHX3	2	10	12	164.326
#477	CEBPA	1	15	16	637.933
#478	TRERF1	1	14	15	66.845
#479	SOX9	1	15	16	96.358
#480	TBX4	1	7	8	207.447
#481	MYOD1	1	10	11	74.394
#482	ZSCAN5A	1	9	10	582.232
#483	ERF	1	10	11	563.705
#484	CBFA2T3	1	10	11	379.783
#485	ZKSCAN2	1	10	11	168.687
#486	SCRT1	1	11	12	397.849
#487	HIRA	1	14	15	242.607
#488	BCL6	1	16	17	1005.161
#489	CTBP1	1	10	11	62.293
#490	HES1	1	15	16	272.842
#491	KLF7	1	16	17	213.36
#492	FOXK1	1	11	12	77.937
#493	ESRRA	1	11	12	135.659
#494	HHEX	1	10	11	861.224
#495	ASCL1	0	12	12	0
#496	TBX1	0	10	10	0
#497	GBX1	0	6	6	0
#498	TRIM25	0	15	15	0
#499	PRRX2	0	13	13	0
#500	ISL2	0	10	10	0