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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF207	77	1	78	2879.99
#2	PHF1	58	4	62	1447.092
#3	EDF1	58	5	63	139.165
#4	YBX1	58	4	62	89.527
#5	CNOT8	51	5	56	6075.017
#6	SMAD4	50	3	53	70.814
#7	ZNF446	47	2	49	189.479
#8	ADNP	44	6	50	270.203
#9	FLI1	44	2	46	117.975
#10	TRIM22	42	9	51	1476.835
#11	ATF1	40	7	47	144.881
#12	MEF2A	38	9	47	984.839
#13	ZNF140	38	8	46	1307.746
#14	RXRA	38	8	46	1080.201
#15	E2F1	37	16	53	4455.374
#16	TFCP2	37	6	43	144.374
#17	DMTF1	37	12	49	355.604
#18	NFYB	36	3	39	32.788
#19	TAF12	36	7	43	329.156
#20	NR2C2	35	13	48	1859.401
#21	NFIX	35	5	40	176.344
#22	ENO1	34	5	39	69.058
#23	ZEB1	33	6	39	1677.324
#24	KLF16	33	5	38	2042.534
#25	ZNF444	32	6	38	707.863
#26	PURA	32	18	50	2600.5
#27	NFE2L2	32	12	44	1415.864
#28	KLF3	31	12	43	925.949
#29	GABPB1	31	15	46	10323.434
#30	TGIF1	30	15	45	1893.717
#31	NFIC	29	10	39	2708.013
#32	RAX2	29	6	35	11892.521
#33	HMGB2	29	14	43	1056.384
#34	CREBL2	29	12	41	984.787
#35	GAS7	28	10	38	5311.155
#36	SCAND1	28	10	38	390.688
#37	STAT5A	28	14	42	2797.747
#38	FOXF1	28	7	35	304.652
#39	KLF9	28	12	40	2172.33
#40	UBN1	28	10	38	832.041
#41	HES6	28	13	41	1627.622
#42	CNBP	28	10	38	1757.988
#43	ERF	28	5	33	2616.573
#44	SNAI2	28	13	41	1598.86
#45	EPAS1	28	14	42	4961.962
#46	FOXO3	27	6	33	64.902
#47	CBFB	27	10	37	1094.498
#48	REST	27	11	38	1059.82
#49	NR2C1	27	13	40	3123.631
#50	NR3C1	27	14	41	1392.425
#51	ETS1	27	5	32	2655.32
#52	ZNF277	27	12	39	6881.135
#53	SIN3A	27	11	38	1341.795
#54	SNAPC4	27	12	39	362.404
#55	JUND	27	9	36	1307.878
#56	EBF1	27	13	40	3138.319
#57	ELF1	26	12	38	1294.246
#58	CREBZF	26	12	38	1092.505
#59	MEF2C	26	6	32	857.035
#60	MYBL2	26	11	37	2722.578
#61	TSHZ1	26	11	37	700.952
#62	NFYC	26	4	30	33.028
#63	STRN3	26	7	33	2851.029
#64	REL	26	8	34	163.606
#65	NFKB1	26	9	35	9795.967
#66	FUBP1	25	14	39	2754.172
#67	HNRNPK	25	5	30	320.377
#68	PLSCR1	25	15	40	2690.53
#69	NFATC4	25	12	37	4244.086
#70	ZNF445	25	5	30	671.761
#71	IKZF1	24	6	30	2080.678
#72	NKX2-1	24	13	37	3437.292
#73	NFATC3	24	15	39	712.457
#74	C5orf41	24	12	36	2013.185
#75	PA2G4	24	11	35	550.176
#76	TCF4	24	14	38	3760.653
#77	STAT2	24	12	36	762.865
#78	FOXN3	23	13	36	825.952
#79	TCF7L2	23	14	37	1580.987
#80	TRPS1	23	11	34	4732.434
#81	FOS	22	10	32	507.475
#82	TSC22D4	22	9	31	402.572
#83	TFDP2	21	14	35	1550.36
#84	ZSCAN21	21	10	31	1367.857
#85	TBX5	21	10	31	2118.588
#86	RCOR1	21	13	34	1556.716
#87	KLF2	21	13	34	1482.313
#88	ELK3	21	13	34	1370.003
#89	STAT3	21	12	33	3089.277
#90	XBP1	21	12	33	1786.783
#91	EVX1	21	8	29	799.416
#92	FOXF2	21	5	26	175.344
#93	NCOR1	21	12	33	233.268
#94	ZNF367	21	7	28	1274.761
#95	RORC	21	13	34	3122.798
#96	RORA	21	13	34	964.856
#97	ZEB2	20	6	26	1590.536
#98	PEG3	20	8	28	1379.443
#99	BCL6	20	11	31	413.064
#100	TCF21	20	9	29	621.259
#101	RUNX2	20	17	37	2273.609
#102	GTF2H4	20	18	38	2400.447
#103	NOLC1	20	12	32	1672.769
#104	PRRX1	20	6	26	502.654
#105	E2F5	20	20	40	1942.956
#106	HOXB4	20	13	33	2114.788
#107	BHLHE41	20	13	33	1824.269
#108	C2orf3	20	15	35	6768.786
#109	CREB1	19	12	31	955.337
#110	TFAP2A	19	20	39	1944.48
#111	SOX4	19	16	35	917.923
#112	DDIT3	19	10	29	1157.138
#113	PRDM1	19	12	31	3639.472
#114	NFX1	19	12	31	639.485
#115	RUNX1	19	12	31	865.159
#116	MSRB2	19	13	32	1123.491
#117	ZNF434	19	11	30	347.195
#118	ETV6	19	9	28	900.451
#119	HNF1B	19	13	32	922.08
#120	TCF25	19	15	34	423.184
#121	PHTF1	18	9	27	1214.096
#122	HEYL	18	8	26	1631.434
#123	ZNF236	18	8	26	214.045
#124	HMG20A	18	7	25	1489.976
#125	ZFPM1	18	5	23	78.692
#126	MEF2D	18	10	28	1368.825
#127	ZNF131	18	17	35	1440.023
#128	TAF5	18	18	36	1006.874
#129	KDM5B	18	10	28	964.112
#130	PTTG1	18	11	29	609.529
#131	ESR1	18	18	36	6579.916
#132	BLZF1	17	10	27	927.124
#133	TCF15	17	8	25	414.078
#134	TGIF2	17	15	32	3113.36
#135	NR4A2	17	9	26	1547.321
#136	BACH1	17	14	31	1024.489
#137	E2F7	17	14	31	829.507
#138	GATAD1	17	8	25	233.815
#139	BHLHE40	17	12	29	1277.979
#140	ZNF148	17	8	25	608.97
#141	HOXC11	17	12	29	1997.63
#142	TAF4	17	8	25	1742.868
#143	TFEB	17	13	30	794.343
#144	FOXA2	17	18	35	2415.826
#145	NFE2L3	17	14	31	10535.043
#146	ETV1	17	16	33	1283.707
#147	NFIA	17	11	28	405.199
#148	CNOT7	16	12	28	2592.121
#149	GTF2H2	16	11	27	226.711
#150	FOXM1	16	11	27	800.689
#151	NFXL1	16	12	28	626.839
#152	ZNF33A	16	9	25	1029.68
#153	MAFB	16	7	23	2431.32
#154	GATA6	16	11	27	711.488
#155	HSF2	16	15	31	1754.24
#156	ARNTL2	16	13	29	1186.196
#157	RB1	16	9	25	818.678
#158	ATF7	16	11	27	480.211
#159	ATF3	16	5	21	97.755
#160	ZNF238	16	17	33	1650.823
#161	MEIS1	16	9	25	1219.659
#162	RCOR2	16	10	26	500.519
#163	BCL11B	16	24	40	2416.413
#164	TSHZ3	16	6	22	207.514
#165	SMAD1	16	9	25	2115.628
#166	KLF6	15	13	28	587.401
#167	MITF	15	22	37	3022.66
#168	ZSCAN16	15	17	32	1456.588
#169	FOXO1	15	20	35	1833.95
#170	RBPJ	15	15	30	568.296
#171	ZHX1	15	18	33	1174.753
#172	TFDP1	15	14	29	758.537
#173	BTG2	15	13	28	1362.162
#174	BUD31	15	13	28	2308.268
#175	MYT1	15	7	22	410.904
#176	KLF4	15	20	35	2104.63
#177	MECOM	15	26	41	4792.989
#178	MYNN	15	10	25	1019.53
#179	LEF1	15	13	28	2034.059
#180	NR2F2	15	14	29	519.851
#181	IRF6	15	21	36	2421.251
#182	MLLT10	15	12	27	285.149
#183	GATAD2B	15	14	29	1469.433
#184	SIX3	14	10	24	1887.568
#185	SOX7	14	11	25	1373.63
#186	SMAD3	14	19	33	2497.467
#187	CSDA	14	10	24	1569.457
#188	SMAD2	14	11	25	423.12
#189	IRF8	14	6	20	299.295
#190	E2F8	14	19	33	975.528
#191	SMAD5	14	13	27	1509.375
#192	MYCL1	14	21	35	3007.49
#193	TSC22D2	14	15	29	981.437
#194	ZFPM2	14	13	27	1164.955
#195	CSRNP2	14	14	28	770.422
#196	HMGA2	14	8	22	340.677
#197	MTA3	14	12	26	2053.403
#198	ETV5	14	24	38	2439.642
#199	ZC3H8	14	15	29	1526.682
#200	CTBP1	13	15	28	1275.662
#201	HOPX	13	22	35	2580.886
#202	HEY2	13	9	22	680.166
#203	VDR	13	19	32	2181.117
#204	YEATS4	13	14	27	4765.951
#205	BNC1	13	7	20	1009.34
#206	PPARA	13	14	27	2807.097
#207	LMO4	13	15	28	894.324
#208	MESP2	13	10	23	2010.6
#209	ATF6	13	12	25	871.835
#210	FOXA1	13	16	29	4129.764
#211	CREM	13	17	30	14971.765
#212	ERG	13	11	24	865.861
#213	NR2F6	13	13	26	746.239
#214	EGR1	13	9	22	552.232
#215	POU5F1B	13	7	20	3573.83
#216	SP140	13	8	21	531.293
#217	JUN	13	15	28	956.718
#218	ZKSCAN1	13	13	26	214.634
#219	HOXD13	13	9	22	1277.308
#220	ATF5	13	18	31	1273.56
#221	ZGPAT	13	10	23	300.993
#222	IRF2	12	11	23	2047.265
#223	FOXD1	12	16	28	1754.104
#224	ZNF91	12	14	26	2707.077
#225	MYC	12	21	33	722.916
#226	HOXB2	12	17	29	3306.914
#227	RUNX3	12	20	32	2983.16
#228	FOSL1	12	16	28	1705.627
#229	SPDEF	12	17	29	1079.044
#230	HCLS1	12	14	26	1840.288
#231	GTF2H3	12	5	17	167.825
#232	TFAP2C	12	19	31	1835.78
#233	HOXC9	12	14	26	1217.42
#234	GATA3	12	15	27	1481.251
#235	UHRF1	12	10	22	851.503
#236	FOXO6	12	16	28	1001.374
#237	ZNF281	12	20	32	2536.241
#238	SPEN	12	9	21	251.278
#239	EGR4	12	7	19	728.279
#240	PPARD	12	12	24	381.541
#241	GTF2I	12	10	22	224.401
#242	SUPT4H1	12	13	25	506.47
#243	FOXC2	12	7	19	679.429
#244	GLI2	12	16	28	4871.246
#245	MYCN	11	13	24	2023.593
#246	TEAD4	11	12	23	1223.51
#247	VAV1	11	13	24	3093.703
#248	EGR3	11	16	27	646.884
#249	ZNF83	11	13	24	3123.406
#250	WNT5A	11	16	27	3392.91
#251	KLF11	11	17	28	2262.003
#252	CREB3L2	11	16	27	805.62
#253	ZHX2	11	15	26	1234.685
#254	ASCL1	11	22	33	2161.851
#255	ZNF45	11	11	22	481.579
#256	SIX1	11	15	26	1541.113
#257	HLF	11	18	29	1243.886
#258	ZNF639	11	12	23	963.045
#259	SIX4	11	15	26	2551.452
#260	MZF1	11	11	22	234.217
#261	CEBPD	11	16	27	609.717
#262	C1orf85	11	16	27	1495.811
#263	HOXB6	11	13	24	960.415
#264	E2F3	11	13	24	1123.302
#265	TFAP2D	11	15	26	1035.911
#266	STAT4	11	16	27	1125.782
#267	LASS6	11	21	32	926.264
#268	IKZF4	11	13	24	3072.402
#269	TP63	11	17	28	1358.5
#270	NPAS2	11	16	27	2817.427
#271	KLF12	11	15	26	962.453
#272	ZNF165	11	18	29	6421.294
#273	BATF2	11	10	21	616.364
#274	YY1	11	13	24	454.994
#275	TCF19	11	16	27	1453.504
#276	RCAN1	10	17	27	1462.656
#277	HMG20B	10	15	25	463.184
#278	GCFC1	10	14	24	1097.72
#279	HMGA1	10	14	24	299.713
#280	MLX	10	16	26	342.778
#281	IRF7	10	16	26	720.692
#282	UBP1	10	17	27	546.212
#283	ASCL2	10	15	25	2826.948
#284	ETS2	10	19	29	938.422
#285	EHF	10	20	30	3365.259
#286	PPARG	10	18	28	1152.127
#287	ZNF256	10	17	27	1727.033
#288	CSRNP1	10	18	28	1041.904
#289	DLX1	10	5	15	279.114
#290	BATF3	10	15	25	1120.699
#291	CSRNP3	10	12	22	1106.965
#292	NEUROD1	10	10	20	640.676
#293	NFATC1	10	19	29	1956.965
#294	FOXE1	9	21	30	1440.935
#295	SALL2	9	16	25	679.926
#296	CLOCK	9	12	21	1119.441
#297	TBX3	9	20	29	1743.132
#298	SREBF1	9	15	24	746.413
#299	ZNF138	9	15	24	639.84
#300	IRX2	9	23	32	1033.06
#301	FOXK1	9	15	24	1540.146
#302	ELF3	9	14	23	1542.693
#303	ARNT	9	19	28	2630.875
#304	SOX10	9	7	16	2305.75
#305	TCFL5	9	21	30	932.013
#306	PBX3	9	19	28	1575.787
#307	MEOX2	9	8	17	131.537
#308	FOXA3	9	14	23	670.599
#309	ZIC2	9	18	27	2196.267
#310	ESRRG	9	17	26	1100.095
#311	HHEX	9	16	25	305.681
#312	ETV4	9	16	25	1203.763
#313	TCF3	9	13	22	693.473
#314	BTAF1	9	13	22	369.276
#315	MESP1	9	11	20	126.14
#316	ZFP36L2	9	11	20	310.701
#317	NR4A3	8	6	14	822.536
#318	BARX1	8	16	24	909.149
#319	SMAD6	8	16	24	693.819
#320	NFIB	8	19	27	427.074
#321	ZNF628	8	16	24	295.533
#322	STAT1	8	22	30	1075.88
#323	EOMES	8	17	25	727.42
#324	MEIS2	8	19	27	2252.682
#325	JDP2	8	17	25	978.315
#326	SOX6	8	19	27	2401.224
#327	MMP14	8	17	25	1052.168
#328	STAT5B	8	9	17	120.167
#329	HOXB3	8	10	18	482.91
#330	DLX4	8	12	20	3319.783
#331	TFEC	8	12	20	333.268
#332	TRIM29	8	20	28	2474.288
#333	HEY1	8	25	33	765.148
#334	TARDBP	8	14	22	806.533
#335	ZFP42	8	14	22	537.354
#336	HIC1	8	14	22	1468.158
#337	THRB	8	11	19	372.432
#338	HOXC4	8	12	20	748.549
#339	SATB1	8	17	25	1528.709
#340	TRERF1	8	12	20	485.863
#341	HOXA1	8	13	21	973.891
#342	KDM5A	8	14	22	231.211
#343	CITED2	8	20	28	10306.115
#344	PBX1	8	17	25	775.32
#345	SMAD9	8	25	33	1344.248
#346	CBL	8	17	25	296.955
#347	NR2F1	8	15	23	859.711
#348	AEBP1	7	17	24	712.228
#349	ZSCAN18	7	18	25	1076.595
#350	NFIL3	7	12	19	534.083
#351	ONECUT2	7	13	20	1664.569
#352	CREB3L4	7	18	25	1209.002
#353	HOXA5	7	13	20	2430.194
#354	HOXD10	7	21	28	2274.088
#355	FOXQ1	7	23	30	1038.564
#356	SATB2	7	19	26	1804.746
#357	HOXA2	7	13	20	1224.659
#358	MEIS3P1	7	19	26	3327.258
#359	TCF7	7	14	21	250.941
#360	NR4A1	7	7	14	205.221
#361	HNF4G	7	13	20	783.264
#362	MNX1	7	13	20	247.926
#363	PRRX2	7	17	24	1336.444
#364	NR5A2	7	9	16	379.944
#365	ZFHX3	7	15	22	787.414
#366	SOX13	7	15	22	3231.619
#367	NR1H3	7	12	19	405.068
#368	SOX11	7	16	23	1358.611
#369	PLAGL2	7	18	25	698.891
#370	MTA1	7	8	15	236.653
#371	LASS2	7	13	20	4178.874
#372	FOXP4	7	19	26	1381.757
#373	HOXD1	7	13	20	1206.018
#374	GRHL2	7	13	20	248.905
#375	HOXC10	7	18	25	1571.913
#376	ZNF133	7	11	18	471.809
#377	TFCP2L1	7	25	32	1088.712
#378	CDKN2A	7	25	32	2273.308
#379	SOX9	7	27	34	2213.101
#380	ZFP90	7	11	18	377.306
#381	HOXB5	6	12	18	334.447
#382	CBFA2T2	6	12	18	503.624
#383	RFX5	6	11	17	608.575
#384	ZBTB38	6	15	21	484.719
#385	TBX15	6	17	23	671.441
#386	MAF	6	19	25	997.681
#387	NR3C2	6	22	28	1328.675
#388	ZNF187	6	14	20	1032.015
#389	TWIST1	6	12	18	380.915
#390	MSX1	6	13	19	1054.567
#391	ZIC1	6	15	21	2778.635
#392	NFAT5	6	11	17	468.245
#393	KLF7	6	22	28	921.583
#394	IRF9	6	14	20	157.247
#395	GATA2	6	20	26	804.156
#396	PBX2	6	14	20	577.472
#397	TEAD2	6	13	19	5650.497
#398	TRIM25	6	15	21	735.261
#399	MAX	6	11	17	263.723
#400	IRX3	6	20	26	1050.977
#401	FOXJ1	6	11	17	581.692
#402	FOSB	6	9	15	219.378
#403	SLC2A4RG	6	19	25	784.895
#404	ZNF24	6	13	19	176.481
#405	HOXB9	6	12	18	912.697
#406	FOSL2	6	19	25	597.593
#407	MAFK	6	17	23	827.925
#408	NFYA	6	21	27	550.788
#409	EGR2	6	19	25	390.121
#410	JUNB	6	13	19	615.276
#411	CTNNB1	6	15	21	483.98
#412	GLI3	5	10	15	595.164
#413	ZNF92	5	11	16	1240.268
#414	MAFF	5	19	24	914.237
#415	RBCK1	5	23	28	609.035
#416	MLL	5	10	15	91.743
#417	FBXW7	5	17	22	447.052
#418	IRX1	5	9	14	420.123
#419	HIRA	5	15	20	361.638
#420	SOX12	5	17	22	499.408
#421	AFF4	5	13	18	379.972
#422	MGA	5	18	23	2565.232
#423	OVOL1	5	17	22	1047.615
#424	TULP4	5	20	25	843.988
#425	TBX10	5	11	16	418.712
#426	RARB	5	21	26	1601.78
#427	SOX2	5	28	33	1219.051
#428	STAT6	5	14	19	307.428
#429	ZNF397	5	13	18	321.218
#430	POU2F3	5	16	21	1276.076
#431	AHR	5	16	21	274.081
#432	PROX1	5	17	22	932.482
#433	HOXB7	5	12	17	496.084
#434	PRDM2	5	16	21	1184.552
#435	IRX5	5	20	25	758.868
#436	TCF7L1	5	18	23	432.744
#437	CEBPA	5	16	21	287.467
#438	IRF4	4	12	16	380.89
#439	ZNF93	4	16	20	1045.37
#440	TAF4B	4	19	23	794.455
#441	HOXA10	4	16	20	370.897
#442	ZSCAN2	4	12	16	473.714
#443	TFAM	4	16	20	434.736
#444	POU3F2	4	14	18	269.627
#445	RUNX1T1	4	16	20	369.558
#446	ZNF33B	4	12	16	2063.311
#447	NR1H4	4	3	7	62.739
#448	TSC22D1	4	16	20	892.68
#449	ZNF232	4	15	19	1539.652
#450	LHX9	4	11	15	411.145
#451	ELF5	4	24	28	474.191
#452	TBX2	4	17	21	656.282
#453	FOXG1	4	12	16	453.478
#454	CREB3L1	4	22	26	800.258
#455	DMRT2	4	13	17	2061.505
#456	SLC30A9	4	13	17	2567.857
#457	PITX2	4	21	25	434.227
#458	NKX3-1	4	22	26	700.011
#459	HOXA3	4	13	17	1051.717
#460	TAF1B	4	15	19	684.469
#461	IRF1	3	17	20	412.207
#462	LCOR	3	16	19	1159.529
#463	IRF5	3	23	26	642.46
#464	HES1	3	26	29	1357.953
#465	PURB	3	15	18	204.593
#466	ZNF323	3	18	21	860.167
#467	ZFP36L1	3	18	21	810.609
#468	PLAG1	3	15	18	6699.886
#469	FOXP1	3	19	22	783.981
#470	ZNF217	3	21	24	168.357
#471	SPIB	3	10	13	140.389
#472	KLF5	3	26	29	955.954
#473	L3MBTL4	3	15	18	633.131
#474	WT1	3	14	17	382.147
#475	ZNF268	3	17	20	195.609
#476	ARNT2	3	17	20	640.826
#477	GLIS2	3	20	23	595.788
#478	PCGF2	3	13	16	53.472
#479	SIX2	3	20	23	1096.131
#480	PAX7	3	12	15	399.155
#481	HOXD8	3	17	20	1732.453
#482	TEF	3	21	24	2783.545
#483	HMBOX1	3	18	21	1246.402
#484	NR1D2	3	14	17	218.258
#485	TCF12	3	10	13	455.795
#486	HOXD4	2	9	11	81.793
#487	TP53	2	16	18	169.757
#488	HIF3A	2	16	18	159.906
#489	RARA	2	16	18	256.596
#490	SP1	2	17	19	69.784
#491	ZNF117	2	16	18	298.351
#492	MXD1	2	18	20	364.656
#493	TBX1	2	19	21	731.195
#494	GLIS3	2	18	20	510.528
#495	SOX15	1	21	22	88.539
#496	FOXC1	1	16	17	110.578
#497	C11orf9	1	21	22	830.569
#498	ISL1	1	16	17	171.035
#499	MKX	1	14	15	78.225
#500	FOXP2	1	23	24	115.485