Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MAF	43	3	46	1627.762
#2	SIX5	43	2	45	712.773
#3	POU3F2	42	6	48	439.968
#4	ZFP36L1	42	7	49	385.359
#5	LEF1	42	2	44	56.091
#6	MLL	40	3	43	1371.149
#7	NEUROD2	40	3	43	1035.601
#8	BARHL1	39	9	48	1786.664
#9	GLI2	38	5	43	1605.047
#10	MYT1L	38	4	42	4402.994
#11	PRRX1	36	2	38	66.74
#12	CITED1	35	8	43	3221.693
#13	PAX3	35	6	41	192.7
#14	LASS6	35	2	37	1017.149
#15	TGIF2	34	5	39	2090.969
#16	OTX2	34	4	38	3636.925
#17	RUNX2	32	2	34	34.071
#18	ESRRG	32	13	45	1094.444
#19	FOXG1	32	4	36	244.752
#20	ZBTB38	32	8	40	770.282
#21	AFF4	31	2	33	22.345
#22	ZEB1	31	10	41	4066.804
#23	ST18	31	6	37	4401.303
#24	MYT1	31	9	40	910.497
#25	RB1	30	6	36	248.851
#26	TCF7L1	30	11	41	2392.881
#27	GTF2I	29	2	31	61.558
#28	THRA	29	10	39	993.814
#29	ZNF192	28	4	32	5314.045
#30	ZNF238	27	8	35	773.043
#31	SOX2	27	9	36	540.594
#32	PKNOX1	26	7	33	479.54
#33	LHX1	26	10	36	905.683
#34	HESX1	25	9	34	574.49
#35	TBR1	25	11	36	616.877
#36	MYC	25	13	38	4209.915
#37	NEUROG1	25	8	33	1277.384
#38	STAT1	25	5	30	243.751
#39	ISL1	24	9	33	2418.155
#40	ZFHX3	24	8	32	3703.037
#41	PBX3	23	11	34	667.399
#42	SP1	23	5	28	157.432
#43	IRX1	23	10	33	250.912
#44	ZFPM2	23	12	35	2079.129
#45	CEBPB	22	8	30	1294.016
#46	MAFF	22	8	30	1268.193
#47	ZFP36L2	22	6	28	664.347
#48	SIX6	22	12	34	1203.352
#49	ZNF91	22	6	28	1497.299
#50	LMX1A	22	9	31	612.503
#51	VTN	22	9	31	901.175
#52	MYCL1	22	6	28	384.717
#53	HOXD8	21	4	25	191.441
#54	LASS5	21	10	31	1359.411
#55	TGIF1	20	10	30	549.324
#56	NRL	20	6	26	742.098
#57	TSHZ3	20	14	34	1900.793
#58	IRX5	20	11	31	946.407
#59	ZIC2	20	14	34	581.919
#60	MEIS1	20	15	35	1724.261
#61	CUX2	20	9	29	1086.577
#62	NFIC	20	8	28	2040.227
#63	TRPS1	20	8	28	1654.026
#64	E2F8	20	11	31	2575.304
#65	TWIST2	19	7	26	962.726
#66	ZSCAN23	19	12	31	929.33
#67	EOMES	19	16	35	1144.042
#68	NKX6-1	19	13	32	1652.622
#69	ETV5	19	9	28	2071.737
#70	KLF16	19	10	29	2745.78
#71	LHX6	19	8	27	223.238
#72	HOXD10	19	6	25	292.886
#73	HDAC1	18	6	24	469.69
#74	DLX4	18	8	26	486.66
#75	NFE2L2	18	12	30	585.5
#76	MEIS3	18	14	32	1278.559
#77	TBX21	18	8	26	3412.542
#78	FOXA1	18	9	27	618.283
#79	YY1	18	9	27	662.017
#80	PAX6	18	11	29	3745.611
#81	PEG3	18	13	31	2205.758
#82	TFAP2A	18	22	40	1430.747
#83	ZSCAN18	18	9	27	917.068
#84	HOXD9	18	6	24	349.761
#85	HOXD11	18	10	28	761.161
#86	RARB	18	12	30	738.891
#87	EMX1	18	10	28	1319.867
#88	THRB	18	9	27	4937.474
#89	SNAI2	18	8	26	1194.231
#90	HAND2	18	14	32	1131.549
#91	RXRG	17	8	25	630.642
#92	CITED2	17	12	29	1705.884
#93	TFEB	17	14	31	3788.47
#94	L3MBTL4	17	14	31	2133.019
#95	ATOH1	17	3	20	72.972
#96	SIX1	17	6	23	1178.532
#97	TCF3	17	11	28	1053.618
#98	TFE3	17	11	28	516.997
#99	ONECUT2	17	11	28	2733.748
#100	NFIX	17	6	23	1297.36
#101	SMAD3	17	12	29	4324.051
#102	TAF4B	17	12	29	1418.366
#103	SATB2	17	14	31	326
#104	TEAD2	17	11	28	2249.863
#105	FOXO1	17	14	31	5361.276
#106	ZFHX4	17	12	29	867.67
#107	HOXD13	16	9	25	551.126
#108	NR2F2	16	13	29	521.582
#109	PURB	16	9	25	406.932
#110	ETV1	16	11	27	2163.203
#111	IRX3	16	12	28	1193.97
#112	SUPT6H	16	9	25	159.29
#113	NR4A1	16	4	20	955.233
#114	ARX	15	9	24	2535.793
#115	ENO1	15	9	24	486.103
#116	RUNX3	15	14	29	4841.429
#117	CSRNP3	15	9	24	577.236
#118	BCL6	15	15	30	2077.145
#119	TEAD4	15	15	30	3641.554
#120	TP53	15	12	27	1872.728
#121	HES1	15	9	24	1709.249
#122	FOXL2	15	16	31	954.5
#123	GLI3	15	16	31	1542.62
#124	FOXQ1	15	9	24	837.906
#125	DLX3	15	7	22	462.456
#126	EBF1	15	12	27	1079.465
#127	PROX1	15	9	24	1207.448
#128	HOXC5	15	10	25	2653.145
#129	EN1	14	9	23	367.248
#130	DMRT2	14	10	24	956.804
#131	DLX6	14	11	25	869.286
#132	FOS	14	6	20	753.598
#133	BCL11B	14	15	29	2137.295
#134	GATA6	14	19	33	2862.474
#135	PBX1	14	12	26	749.961
#136	RARA	14	14	28	1271.616
#137	LHX2	14	10	24	569.629
#138	FOXS1	14	6	20	231.404
#139	NFATC1	14	11	25	2014.389
#140	HEY2	14	13	27	2519.69
#141	NKX3-2	14	10	24	1693.302
#142	ETV6	14	16	30	4686.029
#143	NFATC4	14	16	30	2554.488
#144	MSC	14	12	26	3300.471
#145	ELF1	14	12	26	4557.862
#146	ZEB2	14	10	24	1190.964
#147	ARNTL	14	14	28	1176.007
#148	HOXC4	14	10	24	1742.127
#149	FOXP2	13	11	24	1158.439
#150	NFYA	13	8	21	684.44
#151	ESX1	13	11	24	1216.305
#152	PITX2	13	12	25	1065.72
#153	TCF7	13	13	26	1848.721
#154	TBX1	13	15	28	1125.693
#155	NR2E3	13	6	19	760.031
#156	POU6F2	13	16	29	1733.118
#157	KLF4	13	9	22	1570.431
#158	TFDP2	13	11	24	278.386
#159	RORB	13	10	23	1650.434
#160	NANOG	13	10	23	983.201
#161	TCF7L2	13	19	32	886.784
#162	SP3	13	9	22	287.09
#163	ZNF154	13	12	25	817.101
#164	HOXC10	13	3	16	511.547
#165	ZIC1	13	12	25	4278.083
#166	NR2F1	13	11	24	341.992
#167	TSHZ2	13	21	34	2739.727
#168	STAT5B	12	12	24	3762.918
#169	TFDP1	12	10	22	801.148
#170	ZNF71	12	10	22	1672.434
#171	NR2E1	12	10	22	1758.576
#172	EN2	12	9	21	645.283
#173	ZNF165	12	10	22	1092.481
#174	BNC1	12	14	26	569.935
#175	FOXP1	12	12	24	917.189
#176	ETV4	12	12	24	1821.074
#177	CEBPD	12	8	20	2299.011
#178	SOX10	12	15	27	1445.766
#179	CREB3L1	12	10	22	4454.015
#180	HOPX	12	9	21	1008.791
#181	SIM1	12	21	33	3798.846
#182	MAFK	12	8	20	956.662
#183	IRX2	12	11	23	1731.95
#184	KLF9	12	11	23	725.154
#185	HOXB8	12	14	26	1955.852
#186	SMAD9	12	14	26	1739.646
#187	ERG	12	10	22	617.085
#188	GRHL3	12	14	26	3043.915
#189	ZSCAN20	12	15	27	2851.944
#190	SPDEF	11	10	21	1930.148
#191	HLF	11	11	22	542.805
#192	NKX2-8	11	12	23	1978.244
#193	SOX13	11	11	22	859.609
#194	HOXD4	11	9	20	860.199
#195	EPAS1	11	9	20	1202.239
#196	SREBF1	11	14	25	3014.363
#197	CREB3L2	11	8	19	945.796
#198	SIX2	11	6	17	1632.225
#199	EGR2	11	7	18	720.285
#200	NR2F6	11	12	23	1857.692
#201	HIF3A	11	12	23	1768.048
#202	HES6	11	10	21	1051.754
#203	EHF	11	14	25	1131.033
#204	MYBL2	11	13	24	1066.576
#205	TAL1	11	11	22	1713.642
#206	MSX2	11	6	17	970.178
#207	AHR	11	8	19	306.307
#208	LHX4	11	16	27	702.68
#209	TFAP2C	11	12	23	1228.787
#210	MYCN	11	12	23	899.532
#211	KLF12	11	12	23	452.823
#212	CRX	11	8	19	791.021
#213	FOXO3	11	8	19	188.866
#214	ZSCAN12	10	12	22	861.152
#215	IKZF1	10	12	22	2231.55
#216	RUNX1	10	12	22	2375.663
#217	GAS7	10	14	24	1709.896
#218	PGR	10	13	23	861.396
#219	ZIC5	10	13	23	338.442
#220	NR4A2	10	9	19	1650.294
#221	FOXF1	10	16	26	3210.693
#222	BCL3	10	14	24	1764.039
#223	FOXP4	10	14	24	2143.421
#224	C11orf9	10	13	23	1393.995
#225	SIM2	10	11	21	996.515
#226	ZNF85	10	15	25	1030.16
#227	NPAS2	10	13	23	695.556
#228	NFIA	10	13	23	1136.699
#229	FOSB	10	2	12	148.741
#230	FOXO6	10	11	21	699.478
#231	ATF6B	10	10	20	998.767
#232	ATF3	10	9	19	741.813
#233	PPARD	10	11	21	1007.985
#234	NFKB2	10	10	20	1037.892
#235	TRERF1	10	12	22	1053.997
#236	HOXB7	10	11	21	1476.123
#237	MKX	10	14	24	686.549
#238	FOXE1	9	14	23	2779.148
#239	JUN	9	16	25	628.404
#240	ELF3	9	7	16	888.803
#241	HOXA10	9	7	16	846.122
#242	SOX9	9	10	19	548.279
#243	BHLHE41	9	17	26	1624.511
#244	POU2F2	9	13	22	1589.275
#245	SOX6	9	18	27	1790.94
#246	OLIG2	9	10	19	728.669
#247	PLAG1	9	11	20	2081.287
#248	HOXB3	9	11	20	1125.881
#249	TFAP2B	9	14	23	835.59
#250	SOX5	9	16	25	2734.612
#251	SOX1	9	9	18	2704.925
#252	ESRRB	9	6	15	125.734
#253	HR	9	13	22	650.365
#254	MNX1	9	13	22	1072.006
#255	DLX2	9	10	19	588.604
#256	ETS2	9	15	24	1724.063
#257	LMO4	9	13	22	1230.55
#258	TLX2	9	12	21	2177.404
#259	NR1I3	9	6	15	1634.336
#260	ZNF24	9	17	26	1870.863
#261	GBX2	9	15	24	1447.008
#262	ZIC3	9	13	22	1872.48
#263	DLX1	9	12	21	2074.96
#264	ZSCAN1	9	12	21	1036.287
#265	SOX11	9	9	18	351.193
#266	TSC22D1	9	15	24	1861.464
#267	CBL	8	9	17	1802.843
#268	SOX17	8	10	18	1503.04
#269	DMRT1	8	11	19	632.214
#270	HOXA5	8	4	12	574.371
#271	NR5A1	8	8	16	382.333
#272	MLXIPL	8	10	18	978.719
#273	TFCP2	8	8	16	1168.04
#274	NFIB	8	15	23	2300.344
#275	HOXA1	8	7	15	433.659
#276	RUNX1T1	8	20	28	2376.349
#277	HOXC13	8	12	20	1065.135
#278	BLZF1	8	8	16	925.441
#279	HSF5	8	15	23	1261.941
#280	ONECUT1	8	16	24	2363.338
#281	ZNF219	8	10	18	1490.353
#282	TEAD1	8	13	21	1222.575
#283	HOXB2	8	15	23	972.881
#284	TEF	8	10	18	265.085
#285	ETV7	8	13	21	1088.784
#286	SLC2A4RG	8	13	21	2799.382
#287	SOX8	8	16	24	3121.202
#288	MMP14	8	10	18	359.677
#289	RCAN1	8	12	20	1577.391
#290	SLC26A3	8	13	21	3995.144
#291	ATF7	8	13	21	885.931
#292	DMBX1	8	9	17	745.894
#293	TBX3	8	10	18	709.112
#294	ASCL2	8	13	21	631.137
#295	PAX7	8	11	19	2146.765
#296	TCF20	8	12	20	903.105
#297	FOXN4	8	13	21	634.713
#298	MEF2C	8	17	25	1192.584
#299	FOSL2	8	10	18	904.411
#300	RARG	8	10	18	831.29
#301	VDR	8	13	21	1106.36
#302	ZNF483	7	13	20	2085.137
#303	LHX8	7	20	27	862.674
#304	NEUROD1	7	11	18	583.819
#305	NFATC2	7	13	20	525.923
#306	HNF4G	7	16	23	1127.037
#307	ESR1	7	10	17	1680.18
#308	KLF5	7	14	21	1672.449
#309	SALL1	7	15	22	1735.562
#310	PURA	7	12	19	1799.266
#311	SPIC	7	14	21	1556.952
#312	HIC1	7	10	17	246.38
#313	GCM1	7	13	20	2016.059
#314	SOX18	7	14	21	2255.846
#315	ZNF396	7	12	19	942.44
#316	FOXJ1	7	15	22	1336.689
#317	EGR3	7	2	9	320.414
#318	VSX1	7	14	21	1915.26
#319	MXD1	7	14	21	807.986
#320	NR5A2	7	14	21	871.967
#321	ISX	7	12	19	907.012
#322	SOX15	7	8	15	590.27
#323	IKZF3	7	11	18	963.895
#324	CREM	7	12	19	550.403
#325	ALX1	7	15	22	896.535
#326	BHLHE40	7	13	20	332.081
#327	TBX22	7	15	22	1003.841
#328	TSC22D2	7	8	15	1544.702
#329	PAX8	7	13	20	1269.55
#330	NPAS1	7	16	23	2269.216
#331	HOXC12	7	9	16	745.032
#332	STAT4	7	16	23	2170.702
#333	ATF2	7	14	21	1671.806
#334	PRDM1	7	17	24	969.436
#335	GATA1	7	9	16	567.098
#336	BRD8	7	15	22	862.933
#337	GSX2	7	9	16	408.504
#338	SCAND2	7	13	20	1775.983
#339	NR3C2	7	16	23	388.723
#340	HOXC11	7	11	18	1546.538
#341	GATA5	6	12	18	509.513
#342	ARNTL2	6	10	16	376.488
#343	TP63	6	7	13	896.251
#344	ZFP42	6	11	17	1187.639
#345	CDKN2A	6	14	20	1948.648
#346	RAX2	6	10	16	685.344
#347	TCF21	6	15	21	2077.707
#348	NKX2-3	6	9	15	806.628
#349	ZNF175	6	12	18	1011.929
#350	HOXA3	6	6	12	298.715
#351	RBPJL	6	11	17	1055.781
#352	MEIS2	6	14	20	1352.337
#353	ZNF215	6	18	24	1450.279
#354	PTH	6	14	20	638.757
#355	ARNT	6	11	17	1514.963
#356	HMBOX1	6	13	19	1076.027
#357	CREB5	6	9	15	435.659
#358	HOXA11	6	9	15	1179.481
#359	NANOGNB	6	10	16	766.813
#360	HOXA9	6	6	12	1173.013
#361	PITX1	6	9	15	479.031
#362	FOXC1	6	13	19	1455.378
#363	ANKRD30A	6	14	20	1097.502
#364	NCOR1	6	10	16	1291.384
#365	TWIST1	6	14	20	1042.179
#366	HNRNPAB	6	15	21	910.554
#367	FOXA2	6	14	20	666.984
#368	POU2F1	6	12	18	1091.831
#369	LHX5	6	16	22	543.243
#370	WNT5A	6	19	25	973.331
#371	HMX1	6	12	18	864.991
#372	HES5	6	15	21	1008.943
#373	ELK4	6	12	18	750.93
#374	IRF4	6	10	16	628.991
#375	PKNOX2	6	13	19	1010.349
#376	NPAT	6	13	19	1250.729
#377	AFF1	6	16	22	851.782
#378	FOXI1	6	15	21	1414.878
#379	TADA2A	6	13	19	994.509
#380	SOX21	6	11	17	421.27
#381	PPARA	6	12	18	1498.441
#382	HOXA13	6	14	20	1628.037
#383	FOXF2	6	9	15	405.807
#384	HOXA4	6	6	12	639.602
#385	SOX7	6	11	17	1249.226
#386	SOX30	6	14	20	1247.692
#387	TFEC	5	15	20	8041.515
#388	CREBBP	5	13	18	629.542
#389	EGR4	5	18	23	553.84
#390	STRN3	5	12	17	752.133
#391	HOXC9	5	15	20	363.234
#392	ZKSCAN3	5	10	15	794.835
#393	FOXB1	5	8	13	839.062
#394	MESP1	5	14	19	659.951
#395	POU5F2	5	13	18	944.63
#396	TBX6	5	15	20	856.183
#397	HOXB6	5	12	17	849.382
#398	NFYC	5	7	12	311.525
#399	GSX1	5	13	18	405.237
#400	PHOX2B	5	11	16	900.11
#401	FEV	5	14	19	204.259
#402	ZNF217	5	11	16	624.222
#403	SNAI3	5	11	16	1251.461
#404	TBX5	5	10	15	502.678
#405	JUND	5	11	16	549.168
#406	FOXE3	5	13	18	2347.464
#407	SIX4	5	16	21	1266.932
#408	HSF4	5	13	18	846.659
#409	SPIB	5	13	18	923.608
#410	HMGA2	5	15	20	2275.639
#411	TBX2	5	16	21	1177.409
#412	POU4F2	5	17	22	3150.579
#413	SMAD6	5	14	19	697.967
#414	TFAP2D	5	21	26	821.622
#415	POU4F1	5	16	21	1213.099
#416	GSC2	5	10	15	757.072
#417	SMAD2	5	13	18	459.085
#418	SPEN	5	7	12	224.453
#419	EGR1	5	6	11	66.718
#420	HCFC1	5	13	18	2422.648
#421	MYF6	5	10	15	493.711
#422	KDM5B	5	13	18	1110.545
#423	LZTS1	5	10	15	450.104
#424	HOXA7	5	11	16	956.536
#425	SCAND3	5	13	18	867.976
#426	RORA	5	13	18	854.118
#427	NR4A3	5	12	17	678.531
#428	FOXD2	5	11	16	586.321
#429	HIRA	4	10	14	528.679
#430	HOXA2	4	16	20	1148.753
#431	FOXD3	4	12	16	911.832
#432	MAX	4	10	14	456.354
#433	ISL2	4	19	23	432.709
#434	ZNF81	4	16	20	737.337
#435	PAX4	4	10	14	725.919
#436	TLX3	4	9	13	430.066
#437	IRF6	4	10	14	466.257
#438	ELK1	4	20	24	909.416
#439	MYF5	4	11	15	2147.301
#440	SNAPC5	4	12	16	179.071
#441	TULP4	4	6	10	229.564
#442	TBX20	4	16	20	838.465
#443	POU2F3	4	13	17	396.758
#444	PPARG	4	16	20	729.292
#445	MAFG	4	19	23	758.436
#446	CREB3L3	4	13	17	732.701
#447	TRIM29	4	10	14	1807.542
#448	TFCP2L1	4	13	17	508.758
#449	ZSCAN2	4	14	18	714.526
#450	MIXL1	4	12	16	726.16
#451	LHX9	4	19	23	996.823
#452	ZNF207	4	14	18	1402.611
#453	POU3F1	4	11	15	642.162
#454	HOXD3	4	8	12	67.604
#455	NFE2	4	14	18	1449.321
#456	AHCTF1	4	12	16	595.8
#457	HNF4A	4	13	17	743.922
#458	GLIS3	4	11	15	576.944
#459	ATF5	3	18	21	1166.045
#460	GATA4	3	10	13	440.15
#461	MECOM	3	12	15	571.293
#462	ASCL1	3	13	16	342.037
#463	ZNF287	3	14	17	879.831
#464	ZSCAN4	3	16	19	755.882
#465	TP73	3	14	17	238.924
#466	CSDA	3	16	19	935.637
#467	PLSCR1	3	12	15	1077.012
#468	MYNN	3	14	17	692.192
#469	FOXL1	3	15	18	1439.531
#470	PDX1	3	11	14	356.578
#471	MESP2	3	11	14	192.567
#472	MEOX2	3	13	16	469.394
#473	TFDP3	3	13	16	368.457
#474	CREBZF	3	16	19	461.731
#475	HOXD1	3	12	15	874.916
#476	REST	3	15	18	1024.578
#477	TAF13	3	13	16	681.851
#478	GATA3	3	13	16	342.553
#479	MITF	3	13	16	656.793
#480	NR1H4	3	16	19	885.048
#481	PRDM2	3	13	16	591.486
#482	SMAD4	3	14	17	713.442
#483	ETS1	3	16	19	919.556
#484	RERE	3	11	14	1469.063
#485	SP140	3	15	18	382.963
#486	NKX2-5	3	14	17	601.436
#487	FOXK1	3	14	17	733.666
#488	ESR2	3	14	17	778.761
#489	POU3F3	3	15	18	326.165
#490	RELA	2	11	13	151.258
#491	NKX2-1	2	12	14	648.378
#492	FLI1	2	13	15	794.553
#493	NR0B1	2	13	15	269.892
#494	NR6A1	2	12	14	2184.906
#495	SIN3A	2	12	14	669.618
#496	ZNF131	1	14	15	284.399
#497	POU1F1	1	18	19	763.709
#498	CTBP1	1	13	14	81.901
#499	SIX3	1	16	17	153.007
#500	ZNF80	1	15	16	104.321