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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_egf1520 - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodePLK3

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Upstream (Parents)
   (<<)    ADAM8 → PLK3
   (<<)    AREG → PLK3
   (<<)    CDC42EP2 → PLK3
   (<<)    CYR61 → PLK3
   (<<)    DUSP2 → PLK3
   (<<)    EGR1 → PLK3
   (<<)    HBEGF → PLK3
   (<<)    IER3 → PLK3
   (<<)    PHLDA1 → PLK3
   (<<)    PPRC1 → PLK3
   (<<)    SOCS3 → PLK3
   (<<)    SPRY4 → PLK3
   (<<)    TNF → PLK3

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Downstream (Children)
   PLK3 → ARL4C    (>>)
   PLK3 → BCL3    (>>)
   PLK3 → CD83    (>>)
   PLK3 → CEBPD    (>>)
   PLK3 → CHSY1    (>>)
   PLK3 → CLCF1    (>>)
   PLK3 → CXCR7    (>>)
   PLK3 → DUSP1    (>>)
   PLK3 → DUSP5    (>>)
   PLK3 → EMP1    (>>)
   PLK3 → EPHA2    (>>)
   PLK3 → ERRFI1    (>>)
   PLK3 → FOS    (>>)
   PLK3 → IER2    (>>)
   PLK3 → KLF2    (>>)
   PLK3 → LDLR    (>>)
   PLK3 → MAFF    (>>)
   PLK3 → MMP19    (>>)
   PLK3 → N4BP3    (>>)
   PLK3 → PHLDA2    (>>)
   PLK3 → PIM1    (>>)
   PLK3 → PLAUR    (>>)
   PLK3 → THBS1    (>>)
   PLK3 → TMEM88    (>>)
   PLK3 → YRDC    (>>)
   PLK3 → ZFP36    (>>)