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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_egf1520 - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodeKLK8

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Upstream (Parents)
   (<<)    ADAM12 → KLK8
   (<<)    BMP2 → KLK8
   (<<)    CSF2 → KLK8
   (<<)    DUSP10 → KLK8
   (<<)    FOXQ1 → KLK8
   (<<)    FUT1 → KLK8
   (<<)    GAD1 → KLK8
   (<<)    IL23A → KLK8
   (<<)    KRT14 → KLK8
   (<<)    LEMD1 → KLK8
   (<<)    MMP7 → KLK8
   (<<)    MTSS1 → KLK8
   (<<)    S100A2 → KLK8
   (<<)    SERPINB2 → KLK8
   (<<)    SLC29A1 → KLK8
   (<<)    SLC7A5 → KLK8
   (<<)    STC2 → KLK8
   (<<)    SULT2B1 → KLK8

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Downstream (Children)
   KLK8 → CDK7    (>>)
   KLK8 → EIF2AK2    (>>)
   KLK8 → ELF5    (>>)
   KLK8 → FZD3    (>>)
   KLK8 → KLK10    (>>)
   KLK8 → KLK7    (>>)
   KLK8 → KREMEN2    (>>)
   KLK8 → KRT16    (>>)
   KLK8 → KRT6B    (>>)
   KLK8 → LGALS7    (>>)
   KLK8 → NMU    (>>)
   KLK8 → PGK1    (>>)
   KLK8 → PKIA    (>>)
   KLK8 → RPL22L1    (>>)
   KLK8 → RRAS2    (>>)
   KLK8 → SESN1    (>>)
   KLK8 → TCEB1    (>>)