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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE21029_top500tf - GSE21029 - SiGN-BN HC+Bootstrap
Network DescriptionThe lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia (CLL)
NodeOTX1

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Upstream (Parents)
   (<<)    BCL11B → OTX1
   (<<)    ZNF117 → OTX1
   (<<)    PITX2 → OTX1
   (<<)    SPIC → OTX1
   (<<)    SPIB → OTX1
   (<<)    TEF → OTX1
   (<<)    TBX2 → OTX1
   (<<)    ZNF397 → OTX1
   (<<)    HAND2 → OTX1

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Downstream (Children)
   OTX1 → GATA3    (>>)
   OTX1 → POU2F3    (>>)
   OTX1 → NPAT    (>>)
   OTX1 → EN1    (>>)
   OTX1 → PRDM1    (>>)
   OTX1 → NR2E1    (>>)
   OTX1 → FOXD1    (>>)
   OTX1 → FOXB1    (>>)
   OTX1 → OLIG2    (>>)
   OTX1 → HOXD9    (>>)