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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE21029_top500tf - GSE21029 - SiGN-BN HC+Bootstrap
Network DescriptionThe lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia (CLL)
NodeIRF1

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Upstream (Parents)
   (<<)    TFEC → IRF1
   (<<)    ELK3 → IRF1
   (<<)    KLF10 → IRF1
   (<<)    SATB1 → IRF1
   (<<)    STAT1 → IRF1
   (<<)    HIF1A → IRF1
   (<<)    ZNF117 → IRF1
   (<<)    TSC22D1 → IRF1
   (<<)    FOXP2 → IRF1
   (<<)    ASCL2 → IRF1
   (<<)    MEF2C → IRF1
   (<<)    NANOG → IRF1
   (<<)    HCFC1 → IRF1

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Downstream (Children)
   IRF1 → TSHZ2    (>>)
   IRF1 → FOXC1    (>>)
   IRF1 → CDKN2A    (>>)
   IRF1 → THRA    (>>)
   IRF1 → E2F2    (>>)
   IRF1 → LHX2    (>>)
   IRF1 → POU4F2    (>>)
   IRF1 → PPBPL2    (>>)