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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE21029_top500tf - GSE21029 - SiGN-BN HC+Bootstrap
Network DescriptionThe lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia (CLL)
NodeSIX5

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Upstream (Parents)
   (<<)    HIF1A → SIX5
   (<<)    HOXB3 → SIX5
   (<<)    ETV5 → SIX5
   (<<)    SALL1 → SIX5
   (<<)    ETS1 → SIX5
   (<<)    FOXP2 → SIX5
   (<<)    ZRANB2 → SIX5
   (<<)    XBP1 → SIX5
   (<<)    SCML2 → SIX5
   (<<)    FOSL1 → SIX5

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Downstream (Children)
   SIX5 → IRF5    (>>)
   SIX5 → SMAD1    (>>)
   SIX5 → TRPS1    (>>)
   SIX5 → RUNX2    (>>)
   SIX5 → MSRB2    (>>)
   SIX5 → ZFP37    (>>)
   SIX5 → NR5A2    (>>)
   SIX5 → SOX13    (>>)
   SIX5 → MESP1    (>>)
   SIX5 → ONECUT2    (>>)
   SIX5 → KLF1    (>>)
   SIX5 → PHOX2B    (>>)
   SIX5 → SMAD4    (>>)
   SIX5 → PRDM1    (>>)
   SIX5 → ETV2    (>>)
   SIX5 → ZNF192    (>>)