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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_top500tf - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodeRUNX1

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Upstream (Parents)
   (<<)    PITX2 → RUNX1
   (<<)    ASCL2 → RUNX1
   (<<)    ETV4 → RUNX1
   (<<)    NR3C2 → RUNX1
   (<<)    GRHL3 → RUNX1
   (<<)    MSX1 → RUNX1
   (<<)    NFE2L3 → RUNX1
   (<<)    TGIF2 → RUNX1
   (<<)    BHLHE40 → RUNX1
   (<<)    KLF3 → RUNX1
   (<<)    KLF7 → RUNX1
   (<<)    CBFB → RUNX1
   (<<)    GSC → RUNX1

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Downstream (Children)
   RUNX1 → NFE2    (>>)
   RUNX1 → ONECUT2    (>>)
   RUNX1 → LEF1    (>>)
   RUNX1 → ARNTL2    (>>)
   RUNX1 → SIM2    (>>)
   RUNX1 → TFCP2L1    (>>)
   RUNX1 → SOX4    (>>)
   RUNX1 → BATF    (>>)
   RUNX1 → FOXD2    (>>)
   RUNX1 → BATF3    (>>)
   RUNX1 → CITED2    (>>)
   RUNX1 → ZFP36L1    (>>)
   RUNX1 → E2F2    (>>)
   RUNX1 → MAFG    (>>)
   RUNX1 → KLF11    (>>)
   RUNX1 → THRB    (>>)
   RUNX1 → AHCTF1    (>>)
   RUNX1 → ZNF281    (>>)
   RUNX1 → CREB3    (>>)
   RUNX1 → GBX2    (>>)
   RUNX1 → TULP4    (>>)