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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_top500tf - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodeSIM2

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Upstream (Parents)
   (<<)    FOXQ1 → SIM2
   (<<)    PITX2 → SIM2
   (<<)    ETV4 → SIM2
   (<<)    SPIB → SIM2
   (<<)    NR3C2 → SIM2
   (<<)    KLF4 → SIM2
   (<<)    TRIM29 → SIM2
   (<<)    GRHL3 → SIM2
   (<<)    MSX1 → SIM2
   (<<)    NFE2L3 → SIM2
   (<<)    SIX1 → SIM2
   (<<)    OTX1 → SIM2
   (<<)    TGIF2 → SIM2
   (<<)    KLF7 → SIM2
   (<<)    RUNX1 → SIM2
   (<<)    ZNF397 → SIM2
   (<<)    NR5A2 → SIM2
   (<<)    DLX4 → SIM2

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Downstream (Children)
   SIM2 → HOXB8    (>>)
   SIM2 → TBX10    (>>)
   SIM2 → CREB3L3    (>>)
   SIM2 → ONECUT2    (>>)
   SIM2 → ARNTL2    (>>)
   SIM2 → ZIC5    (>>)
   SIM2 → MSX2    (>>)
   SIM2 → FOXO1    (>>)
   SIM2 → ZIC2    (>>)
   SIM2 → ELF5    (>>)
   SIM2 → E2F5    (>>)
   SIM2 → ZNF256    (>>)
   SIM2 → TBX3    (>>)
   SIM2 → GRHL2    (>>)
   SIM2 → TFAP2C    (>>)
   SIM2 → TCF20    (>>)
   SIM2 → FOXD4    (>>)
   SIM2 → GBX2    (>>)
   SIM2 → MYC    (>>)