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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_top500tf - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodeSTAT3

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Upstream (Parents)
   (<<)    CREB5 → STAT3
   (<<)    CEBPB → STAT3
   (<<)    KCNH8 → STAT3
   (<<)    CSRNP1 → STAT3
   (<<)    HOXB2 → STAT3
   (<<)    IRF1 → STAT3
   (<<)    FOSL2 → STAT3
   (<<)    E2F4 → STAT3
   (<<)    VAV1 → STAT3
   (<<)    STAT5A → STAT3
   (<<)    NFYA → STAT3

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Downstream (Children)
   STAT3 → SOX2    (>>)
   STAT3 → PAX8    (>>)
   STAT3 → BATF2    (>>)
   STAT3 → MECOM    (>>)
   STAT3 → CCRN4L    (>>)
   STAT3 → TLX2    (>>)
   STAT3 → MNX1    (>>)
   STAT3 → ZNF83    (>>)
   STAT3 → HNRNPAB    (>>)
   STAT3 → TCEAL1    (>>)
   STAT3 → IRF8    (>>)
   STAT3 → FOXO3    (>>)