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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HOPX	62	3	65	2882.674
#2	KLF4	56	4	60	474.758
#3	RORA	47	8	55	1065.245
#4	TRIM29	46	7	53	2483.138
#5	TCF4	45	2	47	155.088
#6	SATB1	43	6	49	1246.368
#7	PEG3	40	7	47	279.96
#8	MAF	37	2	39	47.805
#9	PITX1	36	8	44	2116.907
#10	OVOL1	36	6	42	3108.212
#11	MAFB	35	7	42	265.772
#12	PLSCR1	35	9	44	3264.981
#13	BCL6	34	5	39	706.661
#14	PRRX1	34	7	41	591.609
#15	E2F3	33	10	43	2563.383
#16	HCLS1	33	4	37	87.117
#17	FOXM1	33	1	34	46.739
#18	AEBP1	32	5	37	145.16
#19	PTTG1	32	4	36	763.828
#20	BCL11B	31	8	39	678.56
#21	ESR1	31	4	35	801.88
#22	CDKN2A	31	5	36	772.023
#23	TFAM	30	13	43	1860.874
#24	ZEB1	30	7	37	533.344
#25	KLF6	30	5	35	565.093
#26	MEF2C	30	4	34	543.903
#27	MECOM	29	9	38	1324.525
#28	GAS7	29	10	39	268.666
#29	MEIS1	28	13	41	930.805
#30	MGA	27	6	33	6751.898
#31	AR	27	6	33	912.483
#32	ENO1	26	8	34	825.43
#33	CITED2	26	11	37	2149.151
#34	PRDM1	26	6	32	282.166
#35	HOXB6	25	13	38	1727.152
#36	FUBP1	25	4	29	264.363
#37	FOSB	25	8	33	1358.177
#38	REXO4	25	11	36	1864.18
#39	E2F1	25	2	27	721.124
#40	EHF	24	10	34	2020.268
#41	NFYC	24	6	30	813.873
#42	NR2F6	23	11	34	2630.758
#43	CEBPA	23	16	39	5902.137
#44	CBFA2T3	23	12	35	3589.637
#45	KLF10	23	12	35	741.254
#46	FOXF1	23	13	36	831.688
#47	NFIC	23	11	34	1870.595
#48	MAX	23	5	28	3186.081
#49	ZEB2	23	6	29	292.568
#50	HOXD4	22	5	27	1539.718
#51	TFAP2C	22	9	31	3873.53
#52	FOSL2	22	12	34	1170.652
#53	RELA	22	6	28	838.139
#54	FOS	22	4	26	524.677
#55	MAFF	22	7	29	1429.72
#56	MXD1	22	12	34	1190.029
#57	IRF6	22	5	27	274.21
#58	HES1	22	11	33	1251.414
#59	JUND	21	7	28	510.794
#60	NR3C1	21	5	26	1169.782
#61	SALL1	21	10	31	2024.603
#62	ZFPM2	20	11	31	926.623
#63	IRF9	20	7	27	765.551
#64	ATF5	20	10	30	684.36
#65	NR2F2	20	6	26	208.096
#66	KLF2	20	8	28	520.706
#67	STAT1	20	10	30	952.772
#68	TARDBP	20	8	28	292.047
#69	NFATC4	20	7	27	1351.568
#70	BHLHE40	20	9	29	2103.664
#71	JUNB	20	7	27	1162.13
#72	SOX17	20	15	35	1622.078
#73	STAT5A	20	17	37	2699.636
#74	MYCL1	20	8	28	1087.816
#75	SUPT6H	19	10	29	1884.124
#76	TEAD4	19	9	28	321.684
#77	LEF1	19	12	31	1380.991
#78	NR2C1	19	9	28	344.503
#79	BATF	19	12	31	1453.342
#80	TP53	19	9	28	1378.36
#81	E2F8	19	9	28	698.577
#82	HOXA10	19	12	31	3185.273
#83	KLF5	19	16	35	1506.776
#84	TFEB	19	10	29	697.312
#85	NR1I3	18	11	29	4259.916
#86	ZNF277	18	7	25	359.236
#87	ZFHX4	18	7	25	1364.915
#88	SNAPC4	18	11	29	1945.612
#89	ASCL1	18	12	30	3905.587
#90	ZGPAT	18	11	29	2009.887
#91	RXRB	18	9	27	798.481
#92	ELF3	18	9	27	736.096
#93	HMGB2	18	9	27	1440.885
#94	AHR	18	7	25	2752.483
#95	E4F1	18	9	27	525.926
#96	TAF5	18	16	34	1255.455
#97	TP63	17	8	25	470.68
#98	ARNT	17	13	30	1908.9
#99	ZNF117	17	14	31	1139.112
#100	TAF12	17	13	30	2921.694
#101	MYC	17	17	34	2206.35
#102	BTG2	17	10	27	725.466
#103	MYBL2	17	8	25	403.741
#104	NRL	17	7	24	2994.398
#105	TRIM22	17	12	29	648.836
#106	HOXC4	17	10	27	744.867
#107	MITF	17	7	24	359.876
#108	BNC1	17	12	29	1373.664
#109	NR3C2	17	13	30	2116.199
#110	TBX3	16	12	28	766.057
#111	EGR1	16	2	18	32.135
#112	MEOX1	16	13	29	1219.278
#113	ZNF192	16	10	26	2831.449
#114	MMP14	16	15	31	1663.38
#115	TFAP2A	16	14	30	1256.74
#116	E2F4	16	14	30	1972.576
#117	HOXA7	16	16	32	2104.873
#118	MEIS2	16	11	27	1285.888
#119	TADA2A	15	11	26	1673.632
#120	DLX2	15	8	23	1836.03
#121	FOXF2	15	10	25	910.203
#122	ARNT2	15	9	24	1310.447
#123	SOX15	15	9	24	1321.029
#124	ELF5	15	13	28	1688.361
#125	NR2F1	15	13	28	1668.576
#126	GRHL2	15	6	21	1284.623
#127	RUNX1T1	15	15	30	1627.75
#128	TFE3	15	10	25	611.381
#129	ZXDC	15	10	25	407.356
#130	TCF7L2	15	10	25	419.66
#131	ZBTB38	14	13	27	462.68
#132	C11orf9	14	12	26	1474.695
#133	SMAD5	14	6	20	947.68
#134	MNX1	14	12	26	1474.379
#135	CBL	14	9	23	532.836
#136	ZFHX3	14	10	24	1150.816
#137	NFE2L3	14	11	25	648.004
#138	EPAS1	14	13	27	4822.001
#139	TEF	14	16	30	616.462
#140	SOX4	14	11	25	1190.717
#141	MZF1	14	13	27	2106.009
#142	ZNF446	14	7	21	388.612
#143	SP140	13	11	24	765.28
#144	HMGA1	13	12	25	673.081
#145	RARG	13	13	26	1187.823
#146	NKX3-2	13	7	20	1051.043
#147	IRF7	13	11	24	1032.016
#148	ATF6B	13	13	26	1304.19
#149	YY1	13	15	28	1058.088
#150	BARX1	13	6	19	1751.463
#151	ZNF165	13	12	25	1720.792
#152	HOXB2	13	9	22	1314.245
#153	ZHX2	13	8	21	2231.785
#154	ELK3	13	10	23	2029.429
#155	ST18	13	7	20	1607.134
#156	HOXB8	12	9	21	979.837
#157	CREM	12	12	24	1034.632
#158	ISL1	12	14	26	1092.324
#159	PROX1	12	13	25	2553.122
#160	SOX9	12	14	26	1842.457
#161	BACH1	12	8	20	409.324
#162	SNAI2	12	16	28	3218.734
#163	GATA6	12	14	26	1386.341
#164	ZNF131	12	8	20	1009.237
#165	ZFP36L1	12	15	27	2097.419
#166	CREB3L1	12	17	29	1870.246
#167	IKZF1	12	12	24	1190.22
#168	TSC22D1	12	16	28	1502.328
#169	SOX13	12	16	28	1620.103
#170	HOXC10	12	12	24	3857.679
#171	ATF3	12	8	20	281.484
#172	BUD31	12	11	23	1542.814
#173	LHX2	12	10	22	315.615
#174	FOSL1	12	10	22	551.957
#175	ONECUT2	12	15	27	2088.954
#176	WNT5A	12	12	24	737.763
#177	TBX2	12	16	28	1597.897
#178	PAX6	12	14	26	716.105
#179	HEY1	12	13	25	1741.157
#180	PAX4	12	12	24	1639.492
#181	TCF15	12	12	24	990.615
#182	LHX6	12	13	25	1521.114
#183	NEUROG1	12	16	28	2935.142
#184	ZNF202	12	15	27	1563.709
#185	ETS2	12	10	22	1929.608
#186	SOX5	12	7	19	1267.092
#187	BATF3	12	12	24	1805.277
#188	CBFA2T2	12	16	28	2788.7
#189	RUNX3	12	13	25	1046.629
#190	SIX2	11	10	21	863.503
#191	SATB2	11	10	21	1133.152
#192	RBPJL	11	10	21	1547.564
#193	CEBPD	11	6	17	725.381
#194	FOXO1	11	12	23	1241.924
#195	PPARD	11	13	24	1982.267
#196	TRPS1	11	11	22	684.628
#197	SMAD3	11	18	29	2654.155
#198	TFEC	11	12	23	927.079
#199	RUNX1	11	19	30	1592.093
#200	ZNF193	11	11	22	899.345
#201	HINFP	11	14	25	1668.475
#202	HOXA1	11	18	29	2105.765
#203	BCL3	11	15	26	1828.314
#204	ZFP36L2	11	14	25	1095.263
#205	ERF	11	10	21	979.032
#206	WT1	11	10	21	645.249
#207	ZNF45	11	11	22	1305.025
#208	JUN	11	12	23	598.52
#209	MLLT10	11	13	24	3369.525
#210	ZNF91	11	13	24	445.826
#211	ARNTL2	11	10	21	1298.176
#212	ETS1	10	17	27	2565.389
#213	ETV1	10	14	24	1022.184
#214	HR	10	13	23	1112.122
#215	GABPB1	10	15	25	1721.142
#216	MSRB2	10	9	19	463.446
#217	HMX1	10	14	24	1480.581
#218	ATOH1	10	16	26	2422.211
#219	RXRA	10	17	27	1594.393
#220	ETV5	10	8	18	1008.971
#221	CUX2	10	14	24	1620.83
#222	ZNF167	10	17	27	1568.543
#223	GABPA	10	9	19	1749.81
#224	HOXA5	10	7	17	189.858
#225	FOXO3	10	13	23	1243.781
#226	FOXD2	10	12	22	921.041
#227	LMO4	10	16	26	526.258
#228	TLX2	10	11	21	1614.387
#229	CREB3	10	12	22	933.995
#230	ATF6	10	16	26	3951.022
#231	ETV4	10	12	22	1940.407
#232	ESRRA	10	15	25	1729.751
#233	FEV	10	6	16	522.545
#234	HESX1	10	15	25	1447.13
#235	PLAG1	10	7	17	435.02
#236	ZNF238	10	12	22	1564.563
#237	FOXG1	9	8	17	1259.757
#238	TBX10	9	8	17	1474.351
#239	NPAT	9	15	24	2151.178
#240	BHLHE41	9	13	22	1010.724
#241	HOXB7	9	8	17	1160.154
#242	HEYL	9	8	17	923.691
#243	POU2F2	9	9	18	1127.933
#244	CREBBP	9	9	18	1063.278
#245	FOXA1	9	15	24	1234.128
#246	FLI1	9	9	18	492.528
#247	TAF13	9	16	25	1732.8
#248	ESRRB	9	13	22	1028.382
#249	SIM1	9	12	21	1618.837
#250	ZNF93	9	13	22	1650.085
#251	KLF1	9	8	17	485.121
#252	TBX1	9	16	25	1648.102
#253	TCF12	9	11	20	1017.323
#254	RUNX2	9	9	18	1067.515
#255	STRN3	9	13	22	617.398
#256	TGIF1	9	12	21	923.049
#257	HHEX	9	9	18	2021.256
#258	HNF4A	9	11	20	1242.985
#259	NR1I2	9	9	18	730.559
#260	GATA1	9	12	21	991.808
#261	SRF	9	17	26	2583.647
#262	KLF15	9	11	20	1056.745
#263	NR4A2	9	9	18	717.419
#264	BRD8	9	16	25	1091.51
#265	POU3F4	9	12	21	2638.043
#266	EGR3	9	12	21	718.63
#267	ARID3A	8	14	22	2019.373
#268	ZNF174	8	14	22	1467.866
#269	ERG	8	17	25	2441.387
#270	FOXE3	8	12	20	1919.349
#271	PKNOX1	8	10	18	938.137
#272	IRX4	8	12	20	780.337
#273	ZNF3	8	11	19	1434.214
#274	LHX1	8	16	24	1496.979
#275	SOX11	8	15	23	787.478
#276	MSX1	8	12	20	251.536
#277	NR4A3	8	13	21	1009.175
#278	HLF	8	13	21	688.383
#279	RFXAP	8	16	24	736.323
#280	NR1H4	8	14	22	1651.751
#281	ZFP37	8	8	16	1369.937
#282	ZNF155	8	11	19	690.909
#283	ZNF268	8	7	15	949.505
#284	IRX5	8	15	23	638.977
#285	ASCL2	8	9	17	1457.442
#286	ZIC1	8	6	14	947.281
#287	MTA2	8	8	16	266.792
#288	FOXC1	8	10	18	1388.336
#289	LZTS1	8	12	20	1648.111
#290	ALX3	8	14	22	1729.489
#291	ZSCAN18	8	11	19	294.702
#292	HEY2	8	18	26	1625.537
#293	FOXE1	8	16	24	465.288
#294	ZNF83	8	14	22	1519.94
#295	ZNF323	8	10	18	1163.436
#296	HNF1B	8	11	19	1435.282
#297	POU2F3	8	16	24	637.551
#298	EVX1	8	12	20	765.02
#299	NR4A1	8	13	21	1052.053
#300	SOX12	8	13	21	1944.531
#301	NFIB	8	14	22	2059.54
#302	TBX6	8	11	19	1514.646
#303	HIF3A	8	7	15	1087.1
#304	TADA3	8	14	22	1504.604
#305	FOXB1	8	11	19	1070.439
#306	EN2	8	11	19	1212.679
#307	ZIC3	8	11	19	1225.823
#308	SMAD1	8	14	22	1040.804
#309	ZSCAN2	7	13	20	481.673
#310	HOXA9	7	11	18	676.062
#311	FOXD1	7	17	24	548.258
#312	ZNF135	7	11	18	421.713
#313	ZNF287	7	12	19	937.384
#314	CREB5	7	16	23	1165.435
#315	NR0B1	7	20	27	864.929
#316	NR5A2	7	14	21	3079.709
#317	MSX2	7	15	22	1028.824
#318	ZNF444	7	13	20	703.622
#319	DMRT1	7	12	19	1137.131
#320	NFKB2	7	17	24	1210.256
#321	NKX2-1	7	15	22	1604.344
#322	KLF9	7	12	19	1066.486
#323	HOXC13	7	12	19	260.325
#324	REST	7	10	17	418.956
#325	TBX19	7	12	19	1474.556
#326	ZBTB48	7	11	18	296.652
#327	CREBZF	7	10	17	2662.82
#328	GCM1	7	11	18	1928.897
#329	HMGA2	7	12	19	1824.38
#330	FOXJ1	7	9	16	935.375
#331	HOXB1	7	11	18	3290.781
#332	PPARA	7	11	18	2362.466
#333	EMX1	7	12	19	1563.154
#334	PAX7	7	13	20	3666.702
#335	NR6A1	7	13	20	2201.68
#336	TWIST1	7	11	18	842.253
#337	FOXO4	7	13	20	1563.09
#338	ETV2	7	10	17	1298.384
#339	PKNOX2	7	5	12	122.492
#340	TP73	7	10	17	1132.736
#341	ZNF154	7	12	19	916.44
#342	HMG20B	7	12	19	2288.914
#343	POU5F1B	7	12	19	1534.761
#344	YEATS4	7	13	20	731.743
#345	HNF1A	6	12	18	1267.761
#346	NFE2L2	6	10	16	1031.001
#347	MAFK	6	12	18	1236.777
#348	NFE2	6	13	19	1804.831
#349	HOXA3	6	11	17	1108.747
#350	VDR	6	15	21	1906.208
#351	CTBP1	6	12	18	1482.07
#352	EGR2	6	7	13	161.493
#353	ZNF215	6	12	18	1073.144
#354	HOXA2	6	12	18	572.793
#355	E2F2	6	12	18	563.624
#356	ZNF41	6	17	23	1967.281
#357	C2orf3	6	11	17	812.468
#358	HOXC8	6	9	15	903.497
#359	ESR2	6	12	18	858.306
#360	SPI1	6	10	16	1071.621
#361	HAND2	6	13	19	1709.987
#362	RAX	6	12	18	686.735
#363	DLX6	6	12	18	1099.756
#364	NKX2-8	6	14	20	1155.164
#365	FOXA2	6	11	17	514.218
#366	HOXD1	6	15	21	867.503
#367	POU3F3	6	14	20	796.332
#368	MEF2D	6	11	17	1265.939
#369	SIX1	6	17	23	484.957
#370	PRRX2	6	12	18	1433.464
#371	MLL	6	13	19	600.842
#372	ELF4	6	15	21	272.7
#373	STAT6	6	14	20	787.578
#374	SOX2	6	18	24	629.027
#375	RORB	6	11	17	909.956
#376	RARA	6	11	17	338.591
#377	HOXB13	5	11	16	653.382
#378	PAX8	5	18	23	1324.651
#379	ESRRG	5	16	21	1148.256
#380	TCF3	5	18	23	589.129
#381	POU4F1	5	13	18	447.014
#382	CRX	5	14	19	517.448
#383	SPDEF	5	18	23	2297.86
#384	RARB	5	19	24	1531.347
#385	NANOG	5	11	16	460.083
#386	RB1	5	14	19	849.181
#387	MYCN	5	12	17	485.881
#388	POU3F1	5	13	18	1048.074
#389	ZSCAN16	5	14	19	740.915
#390	HIC1	5	12	17	473.147
#391	PPBPL2	5	15	20	570.282
#392	NR2E1	5	8	13	254.761
#393	GLI2	5	15	20	2398.314
#394	TCF7	5	11	16	434.349
#395	KDM5B	5	10	15	529.076
#396	FOXL2	5	17	22	705.186
#397	POU6F2	5	8	13	324.13
#398	SIX3	5	12	17	1332.579
#399	NKX2-5	5	13	18	1230.743
#400	HOXB3	5	16	21	2528.446
#401	SREBF1	5	15	20	591.931
#402	HOXD9	5	8	13	558.277
#403	PHTF1	5	11	16	178.629
#404	ZNF80	5	11	16	845.567
#405	HOXD11	5	11	16	406.295
#406	TFAP2B	5	17	22	1282.658
#407	VTN	5	14	19	679.741
#408	CEBPE	5	14	19	984.756
#409	GBX2	5	9	14	329.295
#410	MBD1	5	14	19	1354.921
#411	E2F5	5	16	21	1171.851
#412	PBX1	5	15	20	1034.69
#413	EGR4	5	15	20	395.258
#414	NEUROD1	5	13	18	862.843
#415	TSC22D2	4	10	14	806.566
#416	ZNF157	4	12	16	606.494
#417	PRDM2	4	11	15	647.701
#418	ZNF132	4	11	15	510.743
#419	IRF4	4	7	11	730.202
#420	PTH	4	14	18	537.419
#421	TBR1	4	11	15	6165.901
#422	RFX5	4	14	18	402.516
#423	HOXD10	4	16	20	2252.702
#424	NFATC1	4	14	18	885.177
#425	NFIX	4	13	17	810.264
#426	PITX2	4	11	15	562.116
#427	ZNF643	4	12	16	1875.03
#428	TSC22D3	4	14	18	411.206
#429	THRA	4	11	15	696.775
#430	ZNF134	4	15	19	889.199
#431	DBP	4	11	15	479.962
#432	TFAP4	4	13	17	888.362
#433	SOX18	4	15	19	517.624
#434	ALX1	4	10	14	496.282
#435	CITED1	4	9	13	392.452
#436	SCRT1	4	7	11	109.436
#437	NFYA	4	17	21	519.192
#438	SRY	4	13	17	779.765
#439	PGR	4	12	16	335.428
#440	ZNF639	4	11	15	664.493
#441	PDX1	4	13	17	1186.728
#442	POU4F3	4	9	13	538.091
#443	GATA3	4	16	20	1512.816
#444	ZNF236	4	16	20	1657.876
#445	SNAPC5	4	13	17	590.744
#446	ZNF81	4	13	17	1153.304
#447	PHOX2B	4	13	17	405.553
#448	EN1	4	15	19	614.645
#449	SCAND2	4	12	16	381.167
#450	SIM2	4	15	19	651.709
#451	STAT2	4	6	10	326.16
#452	NPAS1	4	15	19	487.911
#453	TRIM25	4	14	18	579.391
#454	ARNTL	4	14	18	846.156
#455	CSRNP3	4	13	17	485.586
#456	PPARG	4	13	17	1062.023
#457	TAF1B	4	12	16	826.103
#458	FOXC2	4	9	13	629.967
#459	HNF4G	4	16	20	1733.109
#460	TFDP2	4	13	17	352.748
#461	ONECUT1	4	7	11	809.504
#462	FOXP3	4	14	18	1281.055
#463	TCF21	3	14	17	816.251
#464	GATA4	3	14	17	970.42
#465	ELK4	3	14	17	451.217
#466	MSC	3	17	20	736.488
#467	HOXD3	3	11	14	949.756
#468	FOXH1	3	12	15	506.723
#469	FOXI1	3	9	12	299.115
#470	IKZF3	3	13	16	420.22
#471	KLF12	3	10	13	635.462
#472	HOXA11	3	11	14	382.053
#473	MEOX2	3	10	13	88.256
#474	NR5A1	3	10	13	302.049
#475	RERE	3	14	17	388.527
#476	GSC2	3	21	24	2088.739
#477	SOX30	3	14	17	390.359
#478	ELK1	3	13	16	246.9
#479	HOXD13	3	13	16	447.017
#480	BLZF1	3	15	18	512.383
#481	RCAN1	3	14	17	296.989
#482	OLIG2	3	13	16	667.236
#483	NPAS2	3	13	16	1200.491
#484	TSHZ2	2	13	15	308.733
#485	MYT1L	2	13	15	240.136
#486	POU3F2	2	14	16	230.087
#487	PAX3	2	13	15	311.192
#488	POU6F1	2	13	15	336.14
#489	T	2	11	13	300.414
#490	MLXIPL	2	14	16	1094.342
#491	NFAT5	2	9	11	422.653
#492	SMAD6	2	17	19	282.119
#493	TAL1	1	11	12	612.722
#494	FOXD3	1	14	15	116.434
#495	ZHX3	1	16	17	210.159
#496	TLX3	1	8	9	62.288
#497	SLC26A3	1	10	11	617.661
#498	POU1F1	1	19	20	223.21
#499	TBX5	0	13	13	0
#500	MYF5	0	10	10	0