Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NR3C1	43	1	44	26.66
#2	TCF7L2	42	8	50	5753.074
#3	MYT1L	38	5	43	89.299
#4	FOXD1	38	6	44	2286.721
#5	CUX2	37	4	41	211.997
#6	NR2F2	36	9	45	1808.758
#7	BCL3	36	4	40	1390.813
#8	GATA4	35	10	45	1425.075
#9	GATA2	34	3	37	133.522
#10	FEV	33	7	40	476.086
#11	SUPT6H	33	7	40	3683.535
#12	MSRB2	33	8	41	1106.145
#13	FOXC1	32	6	38	299.347
#14	PLSCR1	31	7	38	811.448
#15	FOSL1	31	12	43	8933.292
#16	WNT5A	31	5	36	1718.201
#17	PHOX2B	29	3	32	65.488
#18	SIX4	29	7	36	11019.793
#19	BCL6	29	7	36	406.851
#20	TRIM22	29	7	36	962.503
#21	SIX1	28	6	34	960.284
#22	TCF7L1	28	7	35	37533.937
#23	SOX11	28	6	34	658.796
#24	CREB3L1	28	10	38	787.382
#25	TWIST2	27	6	33	657.719
#26	HES6	27	12	39	1181.1
#27	SATB1	26	7	33	291.259
#28	ALX1	25	7	32	191.577
#29	ASCL1	25	13	38	1207.763
#30	DLX6	24	9	33	465.173
#31	ZFP36L1	24	12	36	1351.264
#32	RUNX2	24	10	34	363.731
#33	SOX9	24	9	33	7027.885
#34	RORB	23	10	33	518.788
#35	LEF1	23	8	31	1981.541
#36	REST	23	9	32	928.728
#37	GLIS3	23	7	30	425.975
#38	GATA3	23	7	30	235.011
#39	MEF2C	23	10	33	1454.595
#40	PEG3	22	10	32	373.38
#41	BHLHE40	22	12	34	833.877
#42	TFAP2B	22	10	32	1790.506
#43	CITED2	22	11	33	805.547
#44	HOXC10	22	7	29	179.914
#45	RUNX1	22	6	28	1659.748
#46	PROX1	22	9	31	1576.385
#47	ZFP36L2	21	8	29	773.942
#48	MGA	21	15	36	702.949
#49	POU3F2	21	14	35	1644.668
#50	BACH2	21	10	31	223.251
#51	CREBZF	21	12	33	4041.801
#52	TSHZ2	21	8	29	955.803
#53	FLI1	21	9	30	487.428
#54	TFEB	21	9	30	2093.21
#55	CDKN2A	20	11	31	402.942
#56	MYOG	20	11	31	3054.383
#57	FOXO3	20	7	27	12437.741
#58	POU3F1	20	11	31	1036.143
#59	ZBTB17	20	8	28	2614.751
#60	SMAD1	20	5	25	48216.54
#61	ESRRG	19	4	23	244.477
#62	EPAS1	19	10	29	813.445
#63	MECOM	19	12	31	3855.595
#64	TBX3	19	14	33	50118.827
#65	HOXB2	19	8	27	220.627
#66	RCOR1	19	16	35	1751.799
#67	MYCN	18	13	31	654.112
#68	MYT1	18	9	27	550.842
#69	SMAD3	18	9	27	354.694
#70	L3MBTL4	18	12	30	449.812
#71	PRRX1	18	8	26	290.702
#72	HOXD13	18	7	25	202.823
#73	MAFG	18	14	32	1935.027
#74	HOXD11	18	8	26	287.261
#75	MAFB	18	12	30	748.315
#76	RARB	18	12	30	32959.507
#77	BARX1	17	13	30	1646.685
#78	SREBF1	17	8	25	1174.278
#79	TCF19	17	7	24	393.206
#80	HOXA5	17	13	30	1538.879
#81	NFATC2	17	7	24	216.238
#82	BHLHE41	17	12	29	313.232
#83	MAFK	17	14	31	746.613
#84	STAT5A	17	9	26	363.542
#85	ELF5	17	9	26	831.128
#86	E2F7	17	10	27	1430.359
#87	CBFA2T3	17	6	23	1087.791
#88	KLF2	17	10	27	529.827
#89	TCF3	17	9	26	1660.415
#90	GATAD2B	17	10	27	378.587
#91	DLX3	17	15	32	6171.285
#92	ZSCAN18	16	9	25	331.427
#93	LMO4	16	11	27	321.839
#94	FUBP1	16	9	25	1671.836
#95	UHRF1	16	9	25	686.18
#96	NFYA	16	10	26	1896.762
#97	HLF	16	10	26	435.087
#98	KLF17	16	12	28	3596.057
#99	RUNX1T1	16	10	26	2211.866
#100	OVOL1	16	12	28	1083.008
#101	NFIB	16	11	27	287.747
#102	EBF1	16	12	28	929.88
#103	CITED1	15	6	21	127
#104	ZNF207	15	14	29	4290.492
#105	ATOH1	15	9	24	4748.729
#106	RARG	15	10	25	575.924
#107	EGR2	15	11	26	1344.638
#108	ETV3	15	11	26	1943.902
#109	TSHZ3	15	9	24	1612.641
#110	FOXL1	15	11	26	450.672
#111	ZNF3	15	10	25	675.39
#112	HAND1	15	9	24	1203.898
#113	CEBPD	15	11	26	1048.89
#114	TP73	14	7	21	761.32
#115	LHX8	14	10	24	1333.366
#116	CEBPA	14	10	24	313.998
#117	TFE3	14	10	24	2658.287
#118	HMGB2	14	12	26	5984.863
#119	TLX2	14	10	24	587.648
#120	FOXM1	14	4	18	65.452
#121	E2F2	14	11	25	598.693
#122	ELK1	14	12	26	1321.557
#123	NKX2-8	14	15	29	1973.642
#124	MYC	14	9	23	1001.804
#125	NR1I3	14	10	24	1379.614
#126	SP4	14	11	25	1317.535
#127	RXRG	14	11	25	3423.155
#128	MYBL2	14	8	22	229.441
#129	E2F1	14	8	22	244.834
#130	ZNF135	14	9	23	429.6
#131	EGR3	14	10	24	649.264
#132	CREB3L3	13	11	24	761.01
#133	HEY2	13	12	25	1902.895
#134	HMGA1	13	11	24	1129.273
#135	ARNTL2	13	12	25	694.191
#136	NEUROD1	13	8	21	411.834
#137	PAX5	13	11	24	590.715
#138	TFDP2	13	15	28	1248.838
#139	NANOGNB	13	9	22	761.856
#140	PPARG	13	10	23	341.31
#141	FOXF2	13	13	26	1420.948
#142	EGR4	13	16	29	728.434
#143	OTX1	13	12	25	1482.147
#144	GATA5	13	11	24	424.495
#145	FOS	13	13	26	470.11
#146	GBX2	13	10	23	113.623
#147	SCAND2	13	11	24	1192.865
#148	SIX6	13	10	23	372.424
#149	GSX1	13	17	30	2700.929
#150	ZFPM2	13	11	24	638.914
#151	KLF1	13	14	27	2070.897
#152	TGIF1	13	9	22	556.59
#153	NPAS2	13	13	26	353.542
#154	GLI3	13	8	21	784.93
#155	VTN	13	13	26	430.13
#156	ZNF71	13	9	22	470.184
#157	SOX21	13	10	23	4130.697
#158	ZFHX3	13	10	23	316.531
#159	SCRT1	12	8	20	170.943
#160	IRF1	12	8	20	212.587
#161	C12orf28	12	14	26	10767.561
#162	MSC	12	13	25	534.61
#163	ZIC2	12	17	29	5292.521
#164	TP63	12	15	27	1585.427
#165	CSRNP3	12	8	20	315.441
#166	TFAP4	12	10	22	1168.89
#167	ZSCAN12	12	13	25	728.414
#168	KCNH8	12	9	21	293.043
#169	IRX4	12	15	27	1500.217
#170	NPAS1	12	10	22	1173.228
#171	TBX1	12	14	26	1765.92
#172	HOXD3	12	6	18	13640.794
#173	TFCP2L1	12	16	28	1401.522
#174	THRA	12	11	23	1075.21
#175	TCF20	12	14	26	1146.861
#176	HMG20B	12	13	25	811.85
#177	TBR1	12	11	23	1736.283
#178	VAV1	12	12	24	1175.649
#179	POU6F2	12	14	26	1314.592
#180	NKX3-2	12	11	23	2077.754
#181	FOXN3	12	15	27	2065.884
#182	SIX2	12	15	27	33811.396
#183	HOXD4	12	8	20	12862.167
#184	HOXA4	12	8	20	797.183
#185	HES5	12	12	24	1686.706
#186	ZSCAN1	12	7	19	571.828
#187	IRF5	12	14	26	1277.624
#188	ZNF165	12	13	25	565.21
#189	FOXI1	12	11	23	842.858
#190	ZHX3	12	14	26	1540.675
#191	PTTG1	12	9	21	229.974
#192	SOX2	11	10	21	1295.856
#193	POU3F3	11	18	29	1559.257
#194	LHX9	11	12	23	1144.538
#195	ATF5	11	9	20	1037.714
#196	SOX10	11	10	21	1278.306
#197	AFF1	11	13	24	1656.168
#198	DLX4	11	15	26	3589.079
#199	LHX2	11	10	21	1334.656
#200	HMX1	11	12	23	557.31
#201	GRHL3	11	16	27	1940.606
#202	MLXIPL	11	10	21	1116.369
#203	MYNN	11	12	23	3837.856
#204	TSC22D3	11	18	29	2559.739
#205	NR4A2	11	9	20	176.402
#206	TBX21	11	11	22	798.786
#207	FOSL2	11	10	21	312.371
#208	TCF21	11	15	26	1868.839
#209	STAT6	11	13	24	1084.382
#210	TRIM29	11	12	23	1198.509
#211	TBX22	11	11	22	1056.935
#212	FOXD3	11	12	23	2119.726
#213	ONECUT2	11	11	22	308.987
#214	STRN3	11	10	21	929.818
#215	SOX13	11	13	24	599.921
#216	SP3	11	14	25	691.063
#217	NR2F6	11	13	24	2470.553
#218	NR0B1	11	11	22	730.91
#219	SIX3	11	14	25	1032.143
#220	TSC22D1	11	5	16	400.384
#221	TSC22D2	11	12	23	921.302
#222	ATF2	11	15	26	693.464
#223	BNC1	11	13	24	1469.296
#224	EMX1	11	9	20	1419.988
#225	SOX18	11	11	22	932.888
#226	HOXB1	11	9	20	790.624
#227	FOXC2	11	12	23	367.888
#228	ERG	11	15	26	652.41
#229	SMAD9	11	6	17	301.409
#230	MSX1	11	9	20	709.714
#231	TCF15	11	11	22	1688.064
#232	FOXA2	11	10	21	828.941
#233	ZNF367	10	9	19	199.664
#234	HOXB3	10	12	22	1372.729
#235	HR	10	14	24	888.736
#236	SOX30	10	9	19	1699.409
#237	ELK4	10	13	23	11351.412
#238	FOXO1	10	15	25	1186.597
#239	HMX2	10	9	19	845.146
#240	RXRB	10	15	25	1299.811
#241	IKZF1	10	11	21	291.231
#242	SIN3A	10	11	21	775.043
#243	IRX2	10	10	20	851.87
#244	PRDM1	10	14	24	554.794
#245	GLI2	10	9	19	1081.295
#246	STAT5B	10	13	23	423.302
#247	HOXB7	10	14	24	1682.29
#248	EN1	10	14	24	1301.087
#249	C2orf3	10	14	24	3407.168
#250	ZNF90	10	13	23	1186.303
#251	NRL	10	12	22	1166.32
#252	MTA2	10	14	24	905.798
#253	PKNOX2	10	17	27	1721.971
#254	ZNF154	10	17	27	1229.325
#255	GATAD1	10	14	24	811.242
#256	NFATC1	10	10	20	735.187
#257	TBX2	10	11	21	539.021
#258	POU4F3	10	16	26	1498.245
#259	ZNF397	10	14	24	1287.875
#260	NR6A1	10	11	21	677.183
#261	SIM1	10	15	25	832.669
#262	NANOG	10	11	21	639.933
#263	ZFHX4	10	12	22	645.027
#264	HOXC12	10	11	21	874.287
#265	NR2E1	10	11	21	255.47
#266	PURA	10	11	21	607.722
#267	POU1F1	10	13	23	21069.691
#268	HOXD10	10	10	20	339.705
#269	PDX1	10	11	21	700.579
#270	NEUROG1	10	14	24	2586.003
#271	ARX	10	14	24	1227.507
#272	PAX4	10	10	20	1792.31
#273	DMRT2	10	15	25	1669.842
#274	TFAP2D	10	6	16	1052.809
#275	CLOCK	10	9	19	1142.899
#276	HMGA2	10	6	16	71.879
#277	GATA1	10	13	23	2639.011
#278	GAS7	10	9	19	203.705
#279	PITX1	10	18	28	1859.775
#280	PCGF2	10	8	18	486.958
#281	PTH	10	16	26	1090.636
#282	NOTCH1	10	9	19	798.172
#283	ELF4	10	13	23	523.958
#284	WT1	10	10	20	217.923
#285	MLL	10	13	23	463.641
#286	MAF	10	13	23	1267.15
#287	MYCL1	10	9	19	940.944
#288	HNF1B	9	12	21	1809.107
#289	NR3C2	9	16	25	497.43
#290	LMX1A	9	17	26	1632.917
#291	E2F8	9	9	18	213.204
#292	ANKRD30A	9	14	23	2746.999
#293	ZHX2	9	15	24	674.058
#294	C11orf9	9	15	24	1526.519
#295	ASCL2	9	20	29	1547.22
#296	FOXS1	9	12	21	438.882
#297	ETV7	9	13	22	698.399
#298	HOXA7	9	9	18	468.903
#299	ZNF483	9	13	22	1358.383
#300	MMP14	9	8	17	592.97
#301	SLC2A4RG	9	12	21	943.185
#302	JUN	9	11	20	215.26
#303	ZIC3	9	11	20	467.287
#304	ZIC5	9	17	26	828.485
#305	TADA3	9	16	25	1312.914
#306	SOX17	9	12	21	1226.015
#307	LASS5	9	10	19	393.132
#308	SOLH	9	17	26	1002.26
#309	POU4F1	9	10	19	584.189
#310	HNF4A	9	15	24	1419.098
#311	FOXF1	9	14	23	1248.422
#312	HOXA13	9	17	26	1275.705
#313	TFAP2C	9	14	23	1138.103
#314	ALX4	9	14	23	972.883
#315	SOX6	9	12	21	855.766
#316	POU5F1B	9	9	18	1491.526
#317	HNF1A	9	12	21	699.821
#318	TBX6	9	11	20	1035.011
#319	TLX1	9	13	22	14173.419
#320	ZNF287	9	12	21	755.454
#321	LHX1	9	12	21	1450.842
#322	PURB	9	11	20	1590.631
#323	CSDA	9	14	23	1320.36
#324	ZSCAN10	9	9	18	560.088
#325	KLF4	9	12	21	294.625
#326	NR1I2	9	12	21	1456.103
#327	SPDEF	9	12	21	741.542
#328	PPBPL2	9	11	20	586.877
#329	MIXL1	9	13	22	802.113
#330	PLAG1	9	12	21	277.606
#331	NKX6-2	9	15	24	760.549
#332	VDR	9	12	21	686.482
#333	HOXA10	9	15	24	1926.492
#334	BATF2	8	12	20	626.796
#335	DLX1	8	16	24	1087.589
#336	ALX3	8	11	19	332.193
#337	ZIC1	8	12	20	1154.612
#338	HNF4G	8	15	23	1103.307
#339	TBX15	8	12	20	1574.647
#340	NFKB2	8	9	17	2145.721
#341	TAF4	8	10	18	1195.399
#342	USF1	8	13	21	729.736
#343	NR5A1	8	12	20	665.476
#344	LHX6	8	10	18	228.545
#345	NKX2-5	8	14	22	1087.453
#346	NR4A3	8	9	17	194.836
#347	PAX8	8	18	26	1130.758
#348	PRDM2	8	13	21	546.038
#349	SOX15	8	12	20	512.976
#350	POU6F1	8	14	22	276.495
#351	HOXC11	8	11	19	699.583
#352	TBX20	8	14	22	881.828
#353	PITX2	8	16	24	1448.986
#354	PAX6	8	11	19	803.579
#355	MNX1	8	17	25	1363.708
#356	MEIS3	8	12	20	884.876
#357	FOXE1	8	14	22	614.165
#358	SPIB	8	17	25	3538.179
#359	ZBTB38	8	11	19	420.944
#360	GATA6	8	15	23	1129.757
#361	ZSCAN4	8	10	18	857.788
#362	CREM	8	9	17	3442.456
#363	POU2F1	8	15	23	1225.072
#364	KLF9	8	16	24	1632.377
#365	TEAD2	8	14	22	794.185
#366	ZNF219	8	12	20	597.025
#367	DLX2	8	15	23	787.402
#368	HIF3A	8	14	22	798.309
#369	AR	8	13	21	907.79
#370	HCFC1	8	11	19	466.162
#371	MEOX1	7	23	30	1045.766
#372	RORC	7	10	17	746.522
#373	DMRT1	7	14	21	1127.431
#374	NFATC4	7	12	19	602.503
#375	IRX1	7	11	18	1171.766
#376	KDM5B	7	15	22	1676.646
#377	SP140	7	17	24	1074.539
#378	FOXB1	7	12	19	667.589
#379	ZEB2	7	8	15	406.454
#380	FOXL2	7	12	19	689.39
#381	NR2E3	7	13	20	2277.404
#382	ESX1	7	16	23	1405.749
#383	RBPJL	7	12	19	481.795
#384	THRB	7	10	17	2061.653
#385	RORA	7	14	21	710.741
#386	NR5A2	7	19	26	1584.87
#387	NR1H4	7	17	24	1303.881
#388	HESX1	7	9	16	508.692
#389	FOXN4	7	14	21	278.827
#390	TAL1	7	11	18	796.407
#391	RERE	7	12	19	572.833
#392	VSX1	7	15	22	1435.427
#393	NFE2	7	14	21	905.272
#394	IKZF3	7	10	17	509.606
#395	ESR2	7	15	22	1023.733
#396	POU2F2	7	9	16	157.779
#397	SIM2	7	14	21	2726.446
#398	TEF	7	15	22	767.983
#399	TBX5	7	15	22	975.668
#400	FOXD4	7	12	19	1024.251
#401	MYF6	7	11	18	903.2
#402	HNRNPAB	7	16	23	788.338
#403	HOXA2	7	17	24	1434.3
#404	RUNX3	7	14	21	836.032
#405	NR4A1	7	14	21	432.682
#406	MSX2	7	9	16	628.134
#407	HOPX	7	12	19	535.22
#408	HOXD1	7	16	23	1000.209
#409	SOX1	7	11	18	648.675
#410	FOXK1	7	10	17	2327.321
#411	ZNF396	7	17	24	1584.53
#412	IRF6	7	9	16	165.52
#413	ZNF157	7	10	17	395.232
#414	NOBOX	7	15	22	1128.142
#415	BRD8	7	10	17	716.962
#416	RARA	7	12	19	330.126
#417	BCL11B	6	17	23	2920.785
#418	TFAP2A	6	17	23	958.921
#419	OLIG2	6	13	19	673.317
#420	PBX3	6	14	20	713.209
#421	CREBBP	6	13	19	1080.353
#422	JUND	6	12	18	604.345
#423	HIC1	6	15	21	315.366
#424	FOXD2	6	10	16	440.346
#425	NPAT	6	18	24	1143.42
#426	AFF4	6	15	21	732.129
#427	FOXA1	6	13	19	2293.029
#428	NFIX	6	9	15	198.638
#429	FOXP3	6	16	22	1115.419
#430	ZNF19	6	16	22	581.848
#431	HOXB6	6	17	23	861.283
#432	GSC2	6	15	21	607.706
#433	GCM1	6	10	16	557.225
#434	NCOR1	6	14	20	1048.541
#435	ZFPM1	6	11	17	827.773
#436	FOXJ1	6	16	22	916.529
#437	ZNF81	6	16	22	861.22
#438	EN2	6	20	26	1222.24
#439	MEOX2	6	13	19	814.933
#440	ESR1	6	20	26	2098.726
#441	ARNT	6	14	20	381.672
#442	NKX2-3	6	13	19	738.204
#443	HOXB8	6	13	19	448.899
#444	ELF3	6	15	21	1049.315
#445	IRF8	6	9	15	495.305
#446	RXRA	6	11	17	460.376
#447	MITF	6	14	20	857.64
#448	IRF4	6	16	22	1238.066
#449	LZTS1	6	12	18	428.115
#450	PGR	5	10	15	413.654
#451	POU2F3	5	11	16	1457.609
#452	HOXD9	5	14	19	486.903
#453	OTX2	5	17	22	589.821
#454	SOX5	5	12	17	389.343
#455	POU4F2	5	12	17	495.684
#456	RAX2	5	13	18	813.246
#457	KLF15	5	10	15	311.736
#458	NEUROD2	5	14	19	630.738
#459	GATAD2A	5	14	19	854.143
#460	NFE2L2	5	11	16	678.799
#461	SEBOX	5	14	19	578.712
#462	ERF	5	13	18	2155.759
#463	DMBX1	5	14	19	561.366
#464	ST18	5	17	22	1328.001
#465	TFEC	5	18	23	763.882
#466	ZNF131	5	17	22	891.502
#467	HOXA3	5	16	21	730.252
#468	CTBP1	5	9	14	136.976
#469	FOXP2	5	16	21	1194.141
#470	HOXA6	5	15	20	663.755
#471	MYF5	5	12	17	573.414
#472	HOXA9	5	13	18	453.343
#473	ESRRB	5	17	22	683.424
#474	HSF5	4	17	21	526.339
#475	ISX	4	13	17	2097.716
#476	MXD1	4	15	19	576.067
#477	AHR	4	15	19	580.446
#478	SLC26A3	4	10	14	307.584
#479	EHF	4	10	14	522.497
#480	PAX3	4	12	16	548.015
#481	SPIC	4	19	23	502.587
#482	FOXH1	4	14	18	619.076
#483	SMAD6	4	10	14	592.188
#484	NKX2-1	4	11	15	402.429
#485	SATB2	4	13	17	497.549
#486	HIRA	4	15	19	683.27
#487	PAX7	4	14	18	818.279
#488	ONECUT1	4	12	16	378.249
#489	SNAI3	4	18	22	416.796
#490	ZNF215	4	17	21	592.963
#491	PPARA	3	17	20	513.247
#492	MKX	3	22	25	755.312
#493	ETS2	3	14	17	220.983
#494	TADA2A	3	12	15	509.069
#495	POU5F2	3	17	20	480.435
#496	CEBPE	3	15	18	358.619
#497	RCAN1	2	14	16	187.289
#498	SALL1	2	14	16	163.229
#499	ZFP42	2	21	23	906.974
#500	ZNF80	0	18	18	0